Real Estate Investment Properties for Sale in La Mesa, CA

Looking for investment property in La Mesa, CA with high ROI ?

Explore a variety of short-term homes & houses in La Mesa, CA. Invest wisely with VRBO & La Mesa, CA Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in La Mesa, CA

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
9360 Monona Drive La Mesa, CA An Edward H. Fickett Original. Built 1959-- Perched high in the Grossmont Hills of La Mesa...	4 beds \| 2 baths \| 1,825 sq.ft.	$1,390,000	Airbnb cash on cash: 0.46% Traditional cash on cash: 1.77% Airbnb Rental Income: $3765 Traditional Rental Income: $4646 Airbnb ROI: 0.46% Traditional ROI: 1.77%
5440 Baltimore Drive #178 La Mesa, CA Well established and maintained Strawberry Hills HOA in the heart of La Mesa....convenient...	3 beds \| 3 baths \| 1,394 sq.ft.	$720,000	Airbnb cash on cash: 0.93% Traditional cash on cash: 2.8% Airbnb Rental Income: $3070 Traditional Rental Income: $3626 Airbnb ROI: 0.93% Traditional ROI: 2.8%
7337 W Point Ave. La Mesa, CA CHARMING LA MESA GEM WITH GOURMET KITCHEN, SWEEPING VIEWS AND SOLAR!! This beautifully app...	4 beds \| 2 baths \| 1,887 sq.ft.	$989,700	Airbnb cash on cash: 1.35% Traditional cash on cash: 2.79% Airbnb Rental Income: $3765 Traditional Rental Income: $4278 Airbnb ROI: 1.35% Traditional ROI: 2.79%
10028 Resmar Pl La Mesa, CA Mt. Helix Awaits You! Beautiful Single-level 3BR/2BA Home Perched on a Cul-de-Sac. Sit Ato...	3 beds \| 2 baths \| 2,112 sq.ft.	$1,123,000	Airbnb cash on cash: 0.42% Traditional cash on cash: 2.43% Airbnb Rental Income: $3070 Traditional Rental Income: $4468 Airbnb ROI: 0.42% Traditional ROI: 2.43%
3918 Calavo Dr La Mesa, CA Live Off the Grid at the Base of Mt. Helix! Welcome to 3918 Calavo Dr-where sustainability...	3 beds \| 3 baths \| 1,772 sq.ft.	$985,000	Airbnb cash on cash: 0.73% Traditional cash on cash: 3.32% Airbnb Rental Income: $3070 Traditional Rental Income: $4746 Airbnb ROI: 0.73% Traditional ROI: 3.32%
4227 69Th Street La Mesa, CA Welcome to this spacious single-story 4-bedroom home in La Mesa, offering the perfect blen...	4 beds \| 3 baths \| 1,384 sq.ft.	$1,050,000	Airbnb cash on cash: 1.36% Traditional cash on cash: 2.7% Airbnb Rental Income: $3765 Traditional Rental Income: $4260 Airbnb ROI: 1.36% Traditional ROI: 2.7%
4333 Calavo Dr La Mesa, CA 2.25% ASSUMABLE MORTGAGE available to ANY BUYER (subject to lender approval). Live elevate...	4 beds \| 3 baths \| 2,872 sq.ft.	$1,195,000	Airbnb cash on cash: 1.11% Traditional cash on cash: 3.05% Airbnb Rental Income: $3765 Traditional Rental Income: $5098 Airbnb ROI: 1.11% Traditional ROI: 3.05%
6784 Alamo Way La Mesa, CA Over $400k in upgrades since 2020! The stunning, remodeled, 2,152 sqft main house features...	5 beds \| 3 baths \| 2,638 sq.ft.	$1,279,000	Airbnb cash on cash: 5.95% Traditional cash on cash: 2.76% Airbnb Rental Income: $11004 Traditional Rental Income: $5185 Airbnb ROI: 5.95% Traditional ROI: 2.76%
7940 University Avenue #34 La Mesa, CA Approved Short Sale! Opportunity to own your place within walking distance to downtown La...	2 beds \| 2 baths \| 990 sq.ft.	$400,000	Airbnb cash on cash: 4.49% Traditional cash on cash: 4.83% Airbnb Rental Income: $3554 Traditional Rental Income: $2898 Airbnb ROI: 4.49% Traditional ROI: 4.83%
4542 Toni Lane La Mesa, CA 3 bedrooms all with private bathroom. Fully paid off solar. Open floor plan. Detached gara...	3 beds \| 4 baths \| 1,806 sq.ft.	$1,150,000	Airbnb cash on cash: 0.37% Traditional cash on cash: 2.98% Airbnb Rental Income: $3070 Traditional Rental Income: $5155 Airbnb ROI: 0.37% Traditional ROI: 2.98%
5091 Guava Ave La Mesa, CA Great 3 bedroom 2 bath home with a downstairs oversized bonus room, not included in square...	3 beds \| 2 baths \| 1,080 sq.ft.	$849,000	Airbnb cash on cash: 1.53% Traditional cash on cash: 2.94% Airbnb Rental Income: $3070 Traditional Rental Income: $3483 Airbnb ROI: 1.53% Traditional ROI: 2.94%
10013 Pandora Drive La Mesa, CA Welcome to 10013 Pandora Drive, a hidden gem on MT HELIX that combines privacy, charm, and...	4 beds \| 3 baths \| 2,304 sq.ft.	$1,299,000	Airbnb cash on cash: 0.86% Traditional cash on cash: 1.69% Airbnb Rental Income: $3765 Traditional Rental Income: $3951 Airbnb ROI: 0.86% Traditional ROI: 1.69%
9586 Alto Dr La Mesa, CA Variance granted 2-4 Units - Discover this rare Mt. Helix retreat-a multi-generational oas...	6 beds \| 2 baths \| N/A	$1,675,000	Airbnb cash on cash: 4.13% Traditional cash on cash: 2.31% Airbnb Rental Income: $11004 Traditional Rental Income: $6152 Airbnb ROI: 4.13% Traditional ROI: 2.31%
4620 Panchoy Drive La Mesa, CA Gorgeous turn key remodeled home located in wonderful Mt. Helix- Situated on .5 acre flat ...	4 beds \| 3 baths \| 2,171 sq.ft.	$1,249,900	Airbnb cash on cash: 1.23% Traditional cash on cash: 1.87% Airbnb Rental Income: $3765 Traditional Rental Income: $3687 Airbnb ROI: 1.23% Traditional ROI: 1.87%
3834 Polaris Dr. La Mesa, CA Love the idea of a pool but not the upkeep or liability? This community offers the perfect...	4 beds \| 4 baths \| 2,714 sq.ft.	$999,900	Airbnb cash on cash: 1.49% Traditional cash on cash: 3.06% Airbnb Rental Income: $3765 Traditional Rental Income: $4413 Airbnb ROI: 1.49% Traditional ROI: 3.06%
4421 68Th St La Mesa, CA Beautiful 4 bedroom / 2 bath completely remodeled single story home in La Mesa! Kitchen fe...	4 beds \| 2 baths \| 1,757 sq.ft.	$998,000	Airbnb cash on cash: 1.32% Traditional cash on cash: 1.78% Airbnb Rental Income: $3765 Traditional Rental Income: $3372 Airbnb ROI: 1.32% Traditional ROI: 1.78%
10164 Vivera Dr La Mesa, CA Tucked away in one of Mount Helix's most coveted enclaves, this stunning contemporary resi...	4 beds \| 4 baths \| 3,095 sq.ft.	$1,395,000	Airbnb cash on cash: 0.45% Traditional cash on cash: 1.34% Airbnb Rental Income: $3765 Traditional Rental Income: $4103 Airbnb ROI: 0.45% Traditional ROI: 1.34%
4002 Violet La Mesa, CA Nestled in a coveted La Mesa neighborhood, this versatile property offers comfortable livi...	4 beds \| 2 baths \| 2,784 sq.ft.	$1,049,900	Airbnb cash on cash: 1.49% Traditional cash on cash: 4.08% Airbnb Rental Income: $3765 Traditional Rental Income: $5481 Airbnb ROI: 1.49% Traditional ROI: 4.08%
10549 Queen Avenue La Mesa, CA Must see this TROPICAL PARADISE!! The home is custom style, single family residence of 211...	4 beds \| 3 baths \| 2,117 sq.ft.	$1,439,000	Airbnb cash on cash: 0.99% Traditional cash on cash: 1.7% Airbnb Rental Income: $3765 Traditional Rental Income: $3900 Airbnb ROI: 0.99% Traditional ROI: 1.7%
9945 Alto Dr La Mesa, CA 9945 Alto Drive is an architectural retreat nestled in the coveted hills of Mt. Helix, whe...	5 beds \| 5 baths \| 5,065 sq.ft.	$2,250,000	Airbnb cash on cash: 2.44% Traditional cash on cash: 2.78% Airbnb Rental Income: $11004 Traditional Rental Income: $9707 Airbnb ROI: 2.44% Traditional ROI: 2.78%
8007 Wetherly St La Mesa, CA BEAUTIFULLY UPGRADED LA MESA HOME \| 4 BEDROOMS + BONUS ROOM \| FIRST-FLOOR BEDROOM & BATH \|...	4 beds \| 2 baths \| 1,988 sq.ft.	$1,050,000	Airbnb cash on cash: 1.75% Traditional cash on cash: 3.25% Airbnb Rental Income: $3765 Traditional Rental Income: $4416 Airbnb ROI: 1.75% Traditional ROI: 3.25%
3443 Trophy Drive La Mesa, CA Welcome to 3443 Trophy Dr, a beautifully updated home in a quiet and friendly San Diego ne...	4 beds \| 2 baths \| 1,743 sq.ft.	$899,999	Airbnb cash on cash: 1.35% Traditional cash on cash: 2.97% Airbnb Rental Income: $3765 Traditional Rental Income: $4308 Airbnb ROI: 1.35% Traditional ROI: 2.97%
4791 73rd St La Mesa, CA Pending cancellation of current escrow. Big lot! Amazing opportunity for an ADU or off str...	4 beds \| 2 baths \| 1,847 sq.ft.	$850,000	Airbnb cash on cash: 2.35% Traditional cash on cash: 4.29% Airbnb Rental Income: $3765 Traditional Rental Income: $4480 Airbnb ROI: 2.35% Traditional ROI: 4.29%
4284 Panorama Dr La Mesa, CA PRICED TO SELL...Come and view this beautiful open concept Ranch style home featuring orig...	3 beds \| 2 baths \| 1,770 sq.ft.	$890,000	Airbnb cash on cash: 1.1% Traditional cash on cash: 3.43% Airbnb Rental Income: $3070 Traditional Rental Income: $4299 Airbnb ROI: 1.1% Traditional ROI: 3.43%
5030 Helix Ter La Mesa, CA Nestled on a serene 0.63 acre cul-de-sac lot in coveted Mount Helix, this exquisite single...	4 beds \| 2 baths \| 2,095 sq.ft.	$1,595,000	Airbnb cash on cash: 0.26% Traditional cash on cash: 1.35% Airbnb Rental Income: $3765 Traditional Rental Income: $4554 Airbnb ROI: 0.26% Traditional ROI: 1.35%
8195 Chaz Place La Mesa, CA Hereâs a fresh 750-character MLS property description with completely different lang...	5 beds \| 3 baths \| 2,147 sq.ft.	$1,149,999	Airbnb cash on cash: 6.48% Traditional cash on cash: 2.97% Airbnb Rental Income: $11004 Traditional Rental Income: $5231 Airbnb ROI: 6.48% Traditional ROI: 2.97%
4578 Shade Rd La Mesa, CA *Seller is offering a RATE BUYDOWN!* Stunning home RARELY AVAILABLE with luxury, priva...	4 beds \| 3 baths \| 2,320 sq.ft.	$1,387,000	Airbnb cash on cash: 0.64% Traditional cash on cash: 2.19% Airbnb Rental Income: $3765 Traditional Rental Income: $4944 Airbnb ROI: 0.64% Traditional ROI: 2.19%
5450 Kiowa Dr unit: 81 #81 La Mesa, CA Nestled in the desirable northwest corner of La Mesa, this immaculate 3-bedroom + loft , 2...	3 beds \| 3 baths \| 1,379 sq.ft.	$739,900	Airbnb cash on cash: 2.16% Traditional cash on cash: 4.04% Airbnb Rental Income: $3070 Traditional Rental Income: $3669 Airbnb ROI: 2.16% Traditional ROI: 4.04%
4145 Olive Avenue La Mesa, CA Charming 3 beds, 2 baths...Great starter home with potential for some sweat equity. Close ...	3 beds \| 2 baths \| 994 sq.ft.	$750,000	Airbnb cash on cash: 2.11% Traditional cash on cash: 3.72% Airbnb Rental Income: $3070 Traditional Rental Income: $3494 Airbnb ROI: 2.11% Traditional ROI: 3.72%
5700 Baltimore Dr unit: 215 #215 La Mesa, CA Welcome to 5700 Baltimore Dr #215 - your perfect slice of La Mesa living! This 2 bedroom/2...	2 beds \| 2 baths \| 1,038 sq.ft.	$499,000	Airbnb cash on cash: 3.51% Traditional cash on cash: 4.58% Airbnb Rental Income: $3554 Traditional Rental Income: $3272 Airbnb ROI: 3.51% Traditional ROI: 4.58%
4310 Resmar Rd. La Mesa, CA Mid-Century Gem in Mt Helix! This single level home is situated on a huge and level lot wi...	3 beds \| 4 baths \| 1,587 sq.ft.	$1,075,900	Airbnb cash on cash: 0.44% Traditional cash on cash: 2.97% Airbnb Rental Income: $3070 Traditional Rental Income: $4905 Airbnb ROI: 0.44% Traditional ROI: 2.97%
3464 Trophy La Mesa, CA BIG PRICE IMPROVEMENT ALONG WITH INTEREST RATE DROPS, BRING YOUR OFFERS! Don't miss this b...	3 beds \| 2 baths \| 1,047 sq.ft.	$749,000	Airbnb cash on cash: 1.24% Traditional cash on cash: 2.96% Airbnb Rental Income: $3070 Traditional Rental Income: $3571 Airbnb ROI: 1.24% Traditional ROI: 2.96%
7700 Parkway Dr unit: 17 #17 La Mesa, CA PRICE IMPROVEMENT! Rarely available end unit in Parkway Villas with open floor plan & vaul...	2 beds \| 2 baths \| 1,183 sq.ft.	$604,900	Airbnb cash on cash: 2.6% Traditional cash on cash: 3.43% Airbnb Rental Income: $3554 Traditional Rental Income: $3243 Airbnb ROI: 2.6% Traditional ROI: 3.43%
5654 Amaya Dr unit: 150 #150 La Mesa, CA Enjoy the open green space from your ground floor patio. This unit has a great location ne...	2 beds \| 2 baths \| 947 sq.ft.	$498,500	Airbnb cash on cash: 3.55% Traditional cash on cash: 4.21% Airbnb Rental Income: $3554 Traditional Rental Income: $3081 Airbnb ROI: 3.55% Traditional ROI: 4.21%
5350 Baltimore Dr unit: 20 #20 La Mesa, CA Welcome to the desirable garden community of La Miranda, known for its lush landscaping, t...	2 beds \| 2 baths \| 967 sq.ft.	$525,000	Airbnb cash on cash: 3.49% Traditional cash on cash: 4.18% Airbnb Rental Income: $3554 Traditional Rental Income: $3110 Airbnb ROI: 3.49% Traditional ROI: 4.18%
8294 High St La Mesa, CA New Construction - this is one of the last units available in the development! The brand n...	2 beds \| 2 baths \| 1,019 sq.ft.	$425,600	Airbnb cash on cash: 5.67% Traditional cash on cash: 8.45% Airbnb Rental Income: $3554 Traditional Rental Income: $3882 Airbnb ROI: 5.67% Traditional ROI: 8.45%
8296 High St La Mesa, CA New Construction - this is one of the last units available in the development! The brand n...	2 beds \| 2 baths \| 1,019 sq.ft.	$425,600	Airbnb cash on cash: 5.67% Traditional cash on cash: 8.45% Airbnb Rental Income: $3554 Traditional Rental Income: $3882 Airbnb ROI: 5.67% Traditional ROI: 8.45%
4029 CARPENTER LN La Mesa, CA The seller will entertain offers between $1,199,000 and $1,279,000. Welcome to this singl...	3 beds \| 2 baths \| 2,606 sq.ft.	$1,279,000	Airbnb cash on cash: 0.16% Traditional cash on cash: 1.84% Airbnb Rental Income: $3070 Traditional Rental Income: $4369 Airbnb ROI: 0.16% Traditional ROI: 1.84%

Real Estate investment in La-mesa, CA

There are 58 properties for sale in the city of La Mesa . The median list price in La Mesa is $998,950 and the average price per square foot is $557. In October 2025, the average monthly cash on cash return in La Mesa is 3.00%. The average monthly rental income in La Mesa is $4,103.

La-mesa, CA Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 58 investment properties available for sale in La-mesa.

In 2025, the best neighborhood to buy investment property is La Mesa.

The ROI for Long-Term is higher than the Short-Term in La-mesa with average rental income of $4,103.

Your search for investment property begins and ends here

Investment Property for Sale in La Mesa, CA

9360 Monona Drive

La Mesa, CA

4 beds | 2 baths | 1,825 sq.ft.

$1,390,000

Airbnb cash on cash: 0.46%

Traditional cash on cash: 1.77%

Airbnb Rental Income: $3765

Traditional Rental Income: $4646

Airbnb ROI: 0.46%

Traditional ROI: 1.77%

5440 Baltimore Drive #178

La Mesa, CA

3 beds | 3 baths | 1,394 sq.ft.

$720,000

Airbnb cash on cash: 0.93%

Traditional cash on cash: 2.8%

Airbnb Rental Income: $3070

Traditional Rental Income: $3626

Airbnb ROI: 0.93%

Traditional ROI: 2.8%

7337 W Point Ave.

La Mesa, CA

4 beds | 2 baths | 1,887 sq.ft.

$989,700

Airbnb cash on cash: 1.35%

Traditional cash on cash: 2.79%

Airbnb Rental Income: $3765

Traditional Rental Income: $4278

Airbnb ROI: 1.35%

Traditional ROI: 2.79%

10028 Resmar Pl

La Mesa, CA

3 beds | 2 baths | 2,112 sq.ft.

$1,123,000

Airbnb cash on cash: 0.42%

Traditional cash on cash: 2.43%

Airbnb Rental Income: $3070

Traditional Rental Income: $4468

Airbnb ROI: 0.42%

Traditional ROI: 2.43%

3918 Calavo Dr

La Mesa, CA

3 beds | 3 baths | 1,772 sq.ft.

$985,000

Airbnb cash on cash: 0.73%

Traditional cash on cash: 3.32%

Airbnb Rental Income: $3070

Traditional Rental Income: $4746

Airbnb ROI: 0.73%

Traditional ROI: 3.32%

4227 69Th Street

La Mesa, CA

4 beds | 3 baths | 1,384 sq.ft.

$1,050,000

Airbnb cash on cash: 1.36%

Traditional cash on cash: 2.7%

Airbnb Rental Income: $3765

Traditional Rental Income: $4260

Airbnb ROI: 1.36%

Traditional ROI: 2.7%

4333 Calavo Dr

La Mesa, CA

4 beds | 3 baths | 2,872 sq.ft.

$1,195,000

Airbnb cash on cash: 1.11%

Traditional cash on cash: 3.05%

Airbnb Rental Income: $3765

Traditional Rental Income: $5098

Airbnb ROI: 1.11%

Traditional ROI: 3.05%

6784 Alamo Way

La Mesa, CA

5 beds | 3 baths | 2,638 sq.ft.

$1,279,000

Airbnb cash on cash: 5.95%

Traditional cash on cash: 2.76%

Airbnb Rental Income: $11004

Traditional Rental Income: $5185

Airbnb ROI: 5.95%