Real Estate Investment Properties for Sale in Matlacha Isles, FL

Looking for investment property in Matlacha Isles, FL with high ROI ?

Explore a variety of short-term homes & houses in Matlacha Isles, FL. Invest wisely with VRBO & Matlacha Isles, FL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Matlacha Isles, FL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2749 Bruce St MATLACHA ISLES, FL WATERFRONT FISHERMAN'S DREAM HOME - DEEP CANAL ACCESS, 13,000 LB BOAT LIFT & NEW SALTWATER...	3 beds \| 3 baths \| 1,810 sq.ft.	$725,000	Airbnb cash on cash: -0.34% Traditional cash on cash: 2.99% Airbnb Rental Income: $1204 Traditional Rental Income: $3069 Airbnb ROI: -0.34% Traditional ROI: 2.99%
12304 Boat Shell Dr MATLACHA ISLES, FL Discover a true waterfront escape in unincorporated Matlacha Isles-where quiet island livi...	3 beds \| 2 baths \| 1,538 sq.ft.	$869,000	Airbnb cash on cash: -1.14% Traditional cash on cash: 1.66% Airbnb Rental Income: $1204 Traditional Rental Income: $3099 Airbnb ROI: -1.14% Traditional ROI: 1.66%
2504 Bayshore Dr MATLACHA ISLES, FL Rare MILLION DOLLAR VIEW Bay Front Gulf Access Home - Watch Dolphins from Your Backyard*...	2 beds \| 2 baths \| 1,544 sq.ft.	$599,000	Airbnb cash on cash: -0.81% Traditional cash on cash: 3.12% Airbnb Rental Income: $814 Traditional Rental Income: $2782 Airbnb ROI: -0.81% Traditional ROI: 3.12%
11828 Island Ave MATLACHA ISLES, FL Waterfront living at its best in the heart of Matlacha! This fully turnkey, 2-bedroom, 2-b...	2 beds \| 2 baths \| 888 sq.ft.	$468,000	Airbnb cash on cash: -0.68% Traditional cash on cash: 2.61% Airbnb Rental Income: $814 Traditional Rental Income: $1932 Airbnb ROI: -0.68% Traditional ROI: 2.61%
12234 Boat Shell Dr MATLACHA ISLES, FL Calling all boaters and island lifestyle buyers. Welcome to a true waterfront island retre...	3 beds \| 2 baths \| 1,960 sq.ft.	$874,900	Airbnb cash on cash: -0.99% Traditional cash on cash: 2.05% Airbnb Rental Income: $1204 Traditional Rental Income: $3291 Airbnb ROI: -0.99% Traditional ROI: 2.05%
12235 Boat Shell Dr MATLACHA ISLES, FL Boater's Paradise \| No Bridges \| Direct Gulf Access \| Two Boat Lifts \| New 2026 Boat Canop...	3 beds \| 2 baths \| 1,405 sq.ft.	$775,000	Airbnb cash on cash: -1.26% Traditional cash on cash: 0.89% Airbnb Rental Income: $1204 Traditional Rental Income: $2363 Airbnb ROI: -1.26% Traditional ROI: 0.89%
12230 Matlacha Boulevard MATLACHA ISLES, FL DIRECT SAILBOAT ACCESS - NO LOCKS, NO MISERABLE MILE! Completed in July 2024, this brand-n...	3 beds \| 2 baths \| 1,830 sq.ft.	$606,250	Airbnb cash on cash: -0.53% Traditional cash on cash: 3.58% Airbnb Rental Income: $1204 Traditional Rental Income: $3141 Airbnb ROI: -0.53% Traditional ROI: 3.58%
12262 Boat Shell Dr MATLACHA ISLES, FL TURNKEY READY TO MOVE IN ISLAND HOME! Live your best island life in this beautiful fully f...	2 beds \| 2 baths \| 1,244 sq.ft.	$489,000	Airbnb cash on cash: -1.41% Traditional cash on cash: 2.54% Airbnb Rental Income: $814 Traditional Rental Income: $2296 Airbnb ROI: -1.41% Traditional ROI: 2.54%
2562 Bayshore Drive MATLACHA ISLES, FL Welcome to 2562 Bayshore Dr, Matlacha, FL 33993 Saltwater Gulf access - No bridges to open...	2 beds \| 1 baths \| 720 sq.ft.	$339,000	Airbnb cash on cash: -0.17% Traditional cash on cash: 2.85% Airbnb Rental Income: $814 Traditional Rental Income: $1450 Airbnb ROI: -0.17% Traditional ROI: 2.85%
2692 Clyde Street MATLACHA ISLES, FL 2 bedroom/3 bath pool home in Matlacha! This home has a great layout inside and out and th...	2 beds \| 3 baths \| 1,076 sq.ft.	$356,420	Airbnb cash on cash: -0.71% Traditional cash on cash: 5.68% Airbnb Rental Income: $814 Traditional Rental Income: $2630 Airbnb ROI: -0.71% Traditional ROI: 5.68%
2761 Geary St MATLACHA ISLES, FL This is the kind of place people come to Matlacha for, and once they do, they never want t...	2 beds \| 2 baths \| 1,295 sq.ft.	$650,000	Airbnb cash on cash: -1.29% Traditional cash on cash: 1.93% Airbnb Rental Income: $814 Traditional Rental Income: $2441 Airbnb ROI: -1.29% Traditional ROI: 1.93%
12101 Moon Shell Drive MATLACHA ISLES, FL DIRECT GULF ACCESS!!! Located on an oversized cul-de-sac lot with approximately 104 feet o...	2 beds \| 2 baths \| 1,312 sq.ft.	$499,900	Airbnb cash on cash: -1.22% Traditional cash on cash: 2.92% Airbnb Rental Income: $814 Traditional Rental Income: $2424 Airbnb ROI: -1.22% Traditional ROI: 2.92%
5166 Sitka Drive MATLACHA ISLES, FL POOL HOME ON OVER 1/2 AN ACRE CORNER LOT!!! This home was built in 2023 and is in "like ne...	3 beds \| 2 baths \| 1,440 sq.ft.	$422,900	Airbnb cash on cash: 0.63% Traditional cash on cash: 4.8% Airbnb Rental Income: $1204 Traditional Rental Income: $2466 Airbnb ROI: 0.63% Traditional ROI: 4.8%
12196 Matlacha Blvd MATLACHA ISLES, FL Calling all boaters, investors and anyone who wants to live the island life! This is more ...	3 beds \| 2 baths \| 1,935 sq.ft.	$610,000	Airbnb cash on cash: -1.25% Traditional cash on cash: 2.24% Airbnb Rental Income: $1204 Traditional Rental Income: $2851 Airbnb ROI: -1.25% Traditional ROI: 2.24%
2595 Pine St MATLACHA ISLES, FL You have to see this unique opportunity! WITH TRANSFERABLE FLOOD INSURANCE!! This versatil...	2 beds \| 2 baths \| 824 sq.ft.	$266,000	Airbnb cash on cash: -0.53% Traditional cash on cash: 6.24% Airbnb Rental Income: $814 Traditional Rental Income: $2188 Airbnb ROI: -0.53% Traditional ROI: 6.24%
4760 Pine Island Rd NW MATLACHA ISLES, FL Here is your chance to own a slice of waterfront paradise in the historic area of Matlacha...	4 beds \| 4 baths \| 1,284 sq.ft.	$568,000	Airbnb cash on cash: -0.93% Traditional cash on cash: 3.51% Airbnb Rental Income: $1147 Traditional Rental Income: $3121 Airbnb ROI: -0.93% Traditional ROI: 3.51%
12201 Shoreview Dr MATLACHA ISLES, FL Stunning waterfront estate set on 2.24 acres in the heart of Matlacha-truly a boater's par...	4 beds \| 4 baths \| 4,021 sq.ft.	$2,598,000	Airbnb cash on cash: -1.26% Traditional cash on cash: 0.96% Airbnb Rental Income: $1123 Traditional Rental Income: $6302 Airbnb ROI: -1.26% Traditional ROI: 0.96%
2634 Coco Plum Dr MATLACHA ISLES, FL NO FLOODING from any previous hurricanes! OWNER financing available This ELEVATED Gulf...	2 beds \| 2 baths \| 864 sq.ft.	$324,900	Airbnb cash on cash: -0.49% Traditional cash on cash: 4.42% Airbnb Rental Income: $814 Traditional Rental Income: $1992 Airbnb ROI: -0.49% Traditional ROI: 4.42%
4819 Pine Island Rd NW MATLACHA ISLES, FL Wonderful seaside cottage with open water views! On any given day, take in the beautiful s...	2 beds \| 2 baths \| 1,056 sq.ft.	$650,000	Airbnb cash on cash: -0.89% Traditional cash on cash: 1.66% Airbnb Rental Income: $814 Traditional Rental Income: $2098 Airbnb ROI: -0.89% Traditional ROI: 1.66%
2610 Pine Street MATLACHA ISLES, FL Adorable Matlacha cottage on the water nestled just steps away from the heart of the islan...	1 beds \| 1 baths \| 708 sq.ft.	$249,697	Airbnb cash on cash: -1.09% Traditional cash on cash: 5.66% Airbnb Rental Income: $409 Traditional Rental Income: $1744 Airbnb ROI: -1.09% Traditional ROI: 5.66%
2822 Bruce St MATLACHA ISLES, FL Waterfront Island Paradise - Direct Gulf Access, No Bridges! Welcome to your "MOVE IN READ...	2 beds \| 1 baths \| 827 sq.ft.	$419,000	Airbnb cash on cash: -0.59% Traditional cash on cash: 3.03% Airbnb Rental Income: $814 Traditional Rental Income: $1910 Airbnb ROI: -0.59% Traditional ROI: 3.03%
12277 Boat Shell Dr MATLACHA ISLES, FL Direct Gulf-access waterfront home in desirable Matlacha Isles! This recently renovated, c...	3 beds \| 3 baths \| 2,802 sq.ft.	$949,999	Airbnb cash on cash: -0.67% Traditional cash on cash: 2.45% Airbnb Rental Income: $1204 Traditional Rental Income: $3567 Airbnb ROI: -0.67% Traditional ROI: 2.45%
2742 Bruce St MATLACHA ISLES, FL YOUR MATLACHA WATERFRONT DREAM STARTS HERE - FULLY RENOVATED 3+DEN / 2 BATH - DIRECT GULF ...	3 beds \| 2 baths \| 1,702 sq.ft.	$474,900	Airbnb cash on cash: -0.56% Traditional cash on cash: 4.13% Airbnb Rental Income: $1204 Traditional Rental Income: $2896 Airbnb ROI: -0.56% Traditional ROI: 4.13%
2631 Bayshore Dr MATLACHA ISLES, FL Welcome to 2631 Bayshore Drive, a classic Matlacha cottage that perfectly blends Old-Flori...	3 beds \| 2 baths \| 1,326 sq.ft.	$475,000	Airbnb cash on cash: -0.98% Traditional cash on cash: 3.37% Airbnb Rental Income: $1204 Traditional Rental Income: $2789 Airbnb ROI: -0.98% Traditional ROI: 3.37%
2831 Janet Street MATLACHA ISLES, FL Janet St- Island Avenue - Matlacha Living at Its Finest. Experience the essence of Florida...	2 beds \| 2 baths \| 1,176 sq.ft.	$599,900	Airbnb cash on cash: -1.3% Traditional cash on cash: 1.96% Airbnb Rental Income: $814 Traditional Rental Income: $2314 Airbnb ROI: -1.3% Traditional ROI: 1.96%
4736 Pine Island Rd NW MATLACHA ISLES, FL Enjoy the breathtaking sunset views from this amazing Matlacha property. Its's all about l...	2 beds \| 2 baths \| 1,232 sq.ft.	$350,000	Airbnb cash on cash: 0.11% Traditional cash on cash: 6.32% Airbnb Rental Income: $814 Traditional Rental Income: $2532 Airbnb ROI: 0.11% Traditional ROI: 6.32%
8545 Redwood Drive MATLACHA ISLES, FL Motivated sellers-bring all offers! And as an added bonus, the seller's flood insurance po...	2 beds \| 3 baths \| 1,075 sq.ft.	$340,000	Airbnb cash on cash: -0.36% Traditional cash on cash: 4.92% Airbnb Rental Income: $814 Traditional Rental Income: $2176 Airbnb ROI: -0.36% Traditional ROI: 4.92%
11242 Matlacha Ave MATLACHA ISLES, FL This charming home in the picturesque town of Matlacha is just footsteps away from the his...	1 beds \| 1 baths \| 480 sq.ft.	$400,000	Airbnb cash on cash: -1.85% Traditional cash on cash: 1.81% Airbnb Rental Income: $409 Traditional Rental Income: $1526 Airbnb ROI: -1.85% Traditional ROI: 1.81%
2821 Bruce St MATLACHA ISLES, FL Offering direct Gulf access with no bridges or locks, deep water, and a 10,000 lb covered ...	3 beds \| 2 baths \| 1,698 sq.ft.	$530,000	Airbnb cash on cash: -0.04% Traditional cash on cash: 3.33% Airbnb Rental Income: $1204 Traditional Rental Income: $2533 Airbnb ROI: -0.04% Traditional ROI: 3.33%
11494 May St MATLACHA ISLES, FL Located in the heart of Matlacha, 11494 May Street is a designated historic cottage that c...	1 beds \| 1 baths \| 535 sq.ft.	$329,900	Airbnb cash on cash: -2.02% Traditional cash on cash: 2.5% Airbnb Rental Income: $409 Traditional Rental Income: $1554 Airbnb ROI: -2.02% Traditional ROI: 2.5%
2686 Clyde St MATLACHA ISLES, FL This 2 br, 1 bth home located in a small quaint community of gulf access waterfront homes ...	2 beds \| 1 baths \| 855 sq.ft.	$362,500	Airbnb cash on cash: -1.1% Traditional cash on cash: 2.78% Airbnb Rental Income: $814 Traditional Rental Income: $1811 Airbnb ROI: -1.1% Traditional ROI: 2.78%
4874 Pine Island Road NW MATLACHA ISLES, FL TRIPLEX already making money! Welcome to your dream waterfront escape in Matlacha, a uniqu...	4 beds \| 3 baths \| N/A	$549,999	Airbnb cash on cash: -0.36% Traditional cash on cash: 6.92% Airbnb Rental Income: $1147 Traditional Rental Income: $4507 Airbnb ROI: -0.36% Traditional ROI: 6.92%
2669 Coco Plum Dr MATLACHA ISLES, FL Island living with unforgettable sunsets! Completely remodeled with marvelous style, this ...	3 beds \| 2 baths \| 1,533 sq.ft.	$495,000	Airbnb cash on cash: -0.18% Traditional cash on cash: 4.12% Airbnb Rental Income: $1204 Traditional Rental Income: $2803 Airbnb ROI: -0.18% Traditional ROI: 4.12%
2647 Pine St MATLACHA ISLES, FL Discover your slice of paradise in the quiet fishing town of Matlacha Island. This charmin...	2 beds \| 1 baths \| 1,008 sq.ft.	$304,999	Airbnb cash on cash: -0.16% Traditional cash on cash: 4.72% Airbnb Rental Income: $814 Traditional Rental Income: $1936 Airbnb ROI: -0.16% Traditional ROI: 4.72%
11476 May St MATLACHA ISLES, FL Welcome to this opportunity in the charming and colorful fishing village of Matlacha! This...	2 beds \| 2 baths \| 951 sq.ft.	$355,000	Airbnb cash on cash: -0.79% Traditional cash on cash: 3.68% Airbnb Rental Income: $814 Traditional Rental Income: $1979 Airbnb ROI: -0.79% Traditional ROI: 3.68%
4658 Gulf Shore Rd MATLACHA ISLES, FL PRICED TO SELL Flood insurance is transferable to buyer. Policy is paid until January 2026...	3 beds \| 2 baths \| 1,332 sq.ft.	$329,000	Airbnb cash on cash: 0.78% Traditional cash on cash: 5.11% Airbnb Rental Income: $1204 Traditional Rental Income: $2235 Airbnb ROI: 0.78% Traditional ROI: 5.11%
2607 Bayshore Dr MATLACHA ISLES, FL This island home is a boater's dream, offering direct access to the Gulf of Mexico right f...	2 beds \| 2 baths \| 1,500 sq.ft.	$439,000	Airbnb cash on cash: -0.74% Traditional cash on cash: 4.72% Airbnb Rental Income: $814 Traditional Rental Income: $2789 Airbnb ROI: -0.74% Traditional ROI: 4.72%
12206 Boat Shell Drive MATLACHA ISLES, FL Welcome to the largest double lot in Matlacha-an incredibly rare opportunity to live on th...	2 beds \| 1 baths \| 1,352 sq.ft.	$499,999	Airbnb cash on cash: -0.65% Traditional cash on cash: 3% Airbnb Rental Income: $814 Traditional Rental Income: $2198 Airbnb ROI: -0.65% Traditional ROI: 3%
2701 Bruce St MATLACHA ISLES, FL Perfect Opportunity to Customize a Well Built Matlacha Home! This home sits on 100ft of de...	3 beds \| 2 baths \| 1,596 sq.ft.	$679,000	Airbnb cash on cash: -0.6% Traditional cash on cash: 2.85% Airbnb Rental Income: $1204 Traditional Rental Income: $3001 Airbnb ROI: -0.6% Traditional ROI: 2.85%
2809 Cheryl Street MATLACHA ISLES, FL Move In Ready Island Home on Over 100 ft of Deep-Water Access! Located 2 lots from the end...	2 beds \| 2 baths \| 980 sq.ft.	$489,900	Airbnb cash on cash: -1.62% Traditional cash on cash: 1.62% Airbnb Rental Income: $814 Traditional Rental Income: $1976 Airbnb ROI: -1.62% Traditional ROI: 1.62%

Real Estate investment in Matlacha-isles, FL

There are 63 properties for sale in the city of Matlacha Isles . The median list price in Matlacha Isles is $489,900 and the average price per square foot is $338. In March 2026, the average monthly cash on cash return in Matlacha Isles is 3.00%. The average monthly rental income in Matlacha Isles is $2,369.

Matlacha-isles, FL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 63 investment properties available for sale in Matlacha-isles.

In 2026, the best neighborhood to buy investment property is MATLACHA ISLES.

The ROI for Long-Term is higher than the Short-Term in Matlacha-isles with average rental income of $2,369.

Your search for investment property begins and ends here

Investment Property for Sale in Matlacha Isles, FL

2749 Bruce St

MATLACHA ISLES, FL

3 beds | 3 baths | 1,810 sq.ft.

$725,000

Airbnb cash on cash: -0.34%

Traditional cash on cash: 2.99%

Airbnb Rental Income: $1204

Traditional Rental Income: $3069

Airbnb ROI: -0.34%

Traditional ROI: 2.99%

12304 Boat Shell Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,538 sq.ft.

$869,000

Airbnb cash on cash: -1.14%

Traditional cash on cash: 1.66%

Airbnb Rental Income: $1204

Traditional Rental Income: $3099

Airbnb ROI: -1.14%

Traditional ROI: 1.66%

2504 Bayshore Dr

MATLACHA ISLES, FL

2 beds | 2 baths | 1,544 sq.ft.

$599,000

Airbnb cash on cash: -0.81%

Traditional cash on cash: 3.12%

Airbnb Rental Income: $814

Traditional Rental Income: $2782

Airbnb ROI: -0.81%

Traditional ROI: 3.12%

11828 Island Ave

MATLACHA ISLES, FL

2 beds | 2 baths | 888 sq.ft.

$468,000

Airbnb cash on cash: -0.68%

Traditional cash on cash: 2.61%

Airbnb Rental Income: $814

Traditional Rental Income: $1932

Airbnb ROI: -0.68%

Traditional ROI: 2.61%

12234 Boat Shell Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,960 sq.ft.

$874,900

Airbnb cash on cash: -0.99%

Traditional cash on cash: 2.05%

Airbnb Rental Income: $1204

Traditional Rental Income: $3291

Airbnb ROI: -0.99%

Traditional ROI: 2.05%

12235 Boat Shell Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,405 sq.ft.

$775,000

Airbnb cash on cash: -1.26%

Traditional cash on cash: 0.89%

Airbnb Rental Income: $1204

Traditional Rental Income: $2363

Airbnb ROI: -1.26%

Traditional ROI: 0.89%

12230 Matlacha Boulevard

MATLACHA ISLES, FL

3 beds | 2 baths | 1,830 sq.ft.

$606,250

Airbnb cash on cash: -0.53%

Traditional cash on cash: 3.58%

Airbnb Rental Income: $1204

Traditional Rental Income: $3141

Airbnb ROI: -0.53%

Traditional ROI: 3.58%

12262 Boat Shell Dr

MATLACHA ISLES, FL

2 beds | 2 baths | 1,244 sq.ft.

$489,000

Airbnb cash on cash: -1.41%

Traditional cash on cash: 2.54%

Airbnb Rental Income: $814

Traditional Rental Income: $2296

Airbnb ROI: -1.41%