Real Estate Investment Properties for Sale in Matlacha Isles, FL

Looking for investment property in Matlacha Isles, FL with high ROI ?

Explore a variety of short-term homes & houses in Matlacha Isles, FL. Invest wisely with VRBO & Matlacha Isles, FL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Matlacha Isles, FL

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
8642 Whispering Pines Drive MATLACHA ISLES, FL Live the dream on a Southwest Florida island! Nestled on beautiful Pine Island-just 2 mile...	2 beds \| 3 baths \| 1,184 sq.ft.	$499,000	Airbnb cash on cash: 0.01% Traditional cash on cash: 3.77% Airbnb Rental Income: $1044 Traditional Rental Income: $2439 Airbnb ROI: 0.01% Traditional ROI: 3.77%
4767 Pine Island Rd NW MATLACHA ISLES, FL Do not miss this one-of-a-kind Matlacha property! This 3-bedroom, 3-bath home sits on over...	N/A beds \| N/A baths \| 1,915 sq.ft.	$899,900	Airbnb cash on cash: 0.34% Traditional cash on cash: 2.76% Airbnb Rental Income: $2276 Traditional Rental Income: $3732 Airbnb ROI: 0.34% Traditional ROI: 2.76%
12304 Boat Shell Dr MATLACHA ISLES, FL Discover a true waterfront escape in unincorporated Matlacha Isles where quiet island livi...	3 beds \| 2 baths \| 1,538 sq.ft.	$849,000	Airbnb cash on cash: -0.87% Traditional cash on cash: 1.75% Airbnb Rental Income: $1471 Traditional Rental Income: $3106 Airbnb ROI: -0.87% Traditional ROI: 1.75%
2504 Bayshore Dr MATLACHA ISLES, FL MAJOR PRICE REDUCTION!!!!!!! Rare Bay front Opportunity: Move-In Ready with Unrivaled View...	3 beds \| 2 baths \| 1,544 sq.ft.	$550,000	Airbnb cash on cash: 0.28% Traditional cash on cash: 4.53% Airbnb Rental Income: $1471 Traditional Rental Income: $3220 Airbnb ROI: 0.28% Traditional ROI: 4.53%
11859 Island Ave MATLACHA ISLES, FL This stunning custom-built home offers DIRECT ACCESS to the Gulf of Mexico and boasts expa...	5 beds \| 4 baths \| 3,615 sq.ft.	$2,000,000	Airbnb cash on cash: -0.76% Traditional cash on cash: 0.94% Airbnb Rental Income: $2549 Traditional Rental Income: $5083 Airbnb ROI: -0.76% Traditional ROI: 0.94%
2589 Bayshore Dr MATLACHA ISLES, FL Live Your Best Island Life in this Beautiful Direct Deep-Water Access Island Home! Surroun...	3 beds \| 2 baths \| 1,040 sq.ft.	$434,900	Airbnb cash on cash: 0.85% Traditional cash on cash: 3.74% Airbnb Rental Income: $1471 Traditional Rental Income: $2217 Airbnb ROI: 0.85% Traditional ROI: 3.74%
11828 Island Ave MATLACHA ISLES, FL Waterfront living at its best in the HISTORIC VILLAGE OF MATLACHA! This fully turnkey, 2-b...	2 beds \| 2 baths \| 888 sq.ft.	$399,999	Airbnb cash on cash: -0.12% Traditional cash on cash: 4.75% Airbnb Rental Income: $1044 Traditional Rental Income: $2506 Airbnb ROI: -0.12% Traditional ROI: 4.75%
2864 Triggerfish St MATLACHA ISLES, FL MATLACHA, One of the most charming waterfront communities in Florida. A very walkable town...	N/A beds \| N/A baths \| 1,205 sq.ft.	$530,000	Airbnb cash on cash: 1.5% Traditional cash on cash: 3.24% Airbnb Rental Income: $2276 Traditional Rental Income: $2568 Airbnb ROI: 1.5% Traditional ROI: 3.24%
2849 Triggerfish St MATLACHA ISLES, FL ATTENTION INVESTORS, BUILDERS AND SAVVY HOMEOWNERS! Old Florida Garden Style Duplex sited...	N/A beds \| N/A baths \| N/A	$604,900	Airbnb cash on cash: 1.23% Traditional cash on cash: 2.41% Airbnb Rental Income: $2276 Traditional Rental Income: $2371 Airbnb ROI: 1.23% Traditional ROI: 2.41%
2639 Bridgeview St MATLACHA ISLES, FL Welcome to your dream waterfront escape in Matlacha, where tropical charm meets modern con...	2 beds \| 2 baths \| 1,076 sq.ft.	$629,000	Airbnb cash on cash: -0.64% Traditional cash on cash: 1.5% Airbnb Rental Income: $1044 Traditional Rental Income: $1949 Airbnb ROI: -0.64% Traditional ROI: 1.5%
8787 Kodiak Lane MATLACHA ISLES, FL Welcome to your own slice of paradise in the heart of St. James City! This beautifully fin...	2 beds \| 2 baths \| 1,224 sq.ft.	$599,000	Airbnb cash on cash: -0.71% Traditional cash on cash: 1.85% Airbnb Rental Income: $1044 Traditional Rental Income: $2113 Airbnb ROI: -0.71% Traditional ROI: 1.85%
8500 REDWOOD DRIVE MATLACHA ISLES, FL Luxury Island Living!!! This gem includes a 1-year home warranty, $5,000 toward your firs...	4 beds \| 3 baths \| 2,632 sq.ft.	$599,000	Airbnb cash on cash: 1.56% Traditional cash on cash: 5.9% Airbnb Rental Income: $2094 Traditional Rental Income: $3986 Airbnb ROI: 1.56% Traditional ROI: 5.9%
2761 Geary St MATLACHA ISLES, FL INCOME-PRODUCING ELEVATED WATERFRONT HOME IN MATLACHA - NO KNOWN FLOOD INTRUSION & READY F...	2 beds \| 2 baths \| 1,295 sq.ft.	$650,000	Airbnb cash on cash: -0.97% Traditional cash on cash: 2.19% Airbnb Rental Income: $1044 Traditional Rental Income: $2602 Airbnb ROI: -0.97% Traditional ROI: 2.19%
4882 WOODSTOCK Road MATLACHA ISLES, FL *Exclusive Luxury Farm for Sale* Welcome to paradise and the property of your dreams. ...	3 beds \| 3 baths \| 1,816 sq.ft.	$890,000	Airbnb cash on cash: -0.26% Traditional cash on cash: 2.57% Airbnb Rental Income: $1471 Traditional Rental Income: $3385 Airbnb ROI: -0.26% Traditional ROI: 2.57%
4931 Island Acres Court MATLACHA ISLES, FL Just over an Acre of Pure Island Serenity! Nestled at the end of the cul-da-sac for total ...	3 beds \| 3 baths \| 1,975 sq.ft.	$549,000	Airbnb cash on cash: -0.33% Traditional cash on cash: 5.24% Airbnb Rental Income: $1471 Traditional Rental Income: $3894 Airbnb ROI: -0.33% Traditional ROI: 5.24%
11306 Matlacha Ave MATLACHA ISLES, FL Just needs some love and a full rehab! **DIRECT SAILBOAT ACCESS* Deep water and less t...	N/A beds \| N/A baths \| 1,405 sq.ft.	$299,900	Airbnb cash on cash: 4.02% Traditional cash on cash: 7.51% Airbnb Rental Income: $2276 Traditional Rental Income: $2693 Airbnb ROI: 4.02% Traditional ROI: 7.51%
11599 Island Ave MATLACHA ISLES, FL Experience premier waterfront luxury in this impeccably renovated 2-bed, 2-bath coastal sa...	2 beds \| 2 baths \| 1,715 sq.ft.	$995,000	Airbnb cash on cash: -0.87% Traditional cash on cash: 2.41% Airbnb Rental Income: $1044 Traditional Rental Income: $3723 Airbnb ROI: -0.87% Traditional ROI: 2.41%
12279 Matlacha Blvd MATLACHA ISLES, FL Old Florida charm meets waterfront living in the heart of Matlacha Isles. Situated on a ra...	2 beds \| 2 baths \| 1,320 sq.ft.	$549,900	Airbnb cash on cash: -0.31% Traditional cash on cash: 3.17% Airbnb Rental Income: $1044 Traditional Rental Income: $2472 Airbnb ROI: -0.31% Traditional ROI: 3.17%
12065 Boat Shell Dr MATLACHA ISLES, FL AMAZING PRICE for this beautifully remodeled 3-bedroom, 2-bathroom home located in the des...	3 beds \| 2 baths \| 1,054 sq.ft.	$500,000	Airbnb cash on cash: -0.87% Traditional cash on cash: 3.02% Airbnb Rental Income: $1471 Traditional Rental Income: $2855 Airbnb ROI: -0.87% Traditional ROI: 3.02%
12196 Matlacha Blvd MATLACHA ISLES, FL Calling all boaters, investors and anyone who wants to live the island life! This is more ...	3 beds \| 2 baths \| 1,935 sq.ft.	$595,000	Airbnb cash on cash: -0.86% Traditional cash on cash: 4.4% Airbnb Rental Income: $1471 Traditional Rental Income: $3959 Airbnb ROI: -0.86% Traditional ROI: 4.4%
2691 Geary St MATLACHA ISLES, FL WELCOME TO YOUR MATLACHA FISHING PARADISE! Just four homes from the channel, this DIRECT G...	2 beds \| 1 baths \| 1,040 sq.ft.	$519,000	Airbnb cash on cash: -0.55% Traditional cash on cash: 5.76% Airbnb Rental Income: $1044 Traditional Rental Income: $3743 Airbnb ROI: -0.55% Traditional ROI: 5.76%
4760 Pine Island Rd NW MATLACHA ISLES, FL ACCEPTING BACK-UP OFFERSHere is your chance to own a slice of waterfront paradise in t...	4 beds \| 4 baths \| 1,284 sq.ft.	$568,000	Airbnb cash on cash: 0.56% Traditional cash on cash: 9.71% Airbnb Rental Income: $2094 Traditional Rental Income: $6407 Airbnb ROI: 0.56% Traditional ROI: 9.71%
12201 Shoreview Dr MATLACHA ISLES, FL Stunning waterfront estate set on 2.24 acres in the heart of Matlacha-truly a boater's par...	4 beds \| 4 baths \| 4,021 sq.ft.	$2,598,000	Airbnb cash on cash: -0.77% Traditional cash on cash: 2.78% Airbnb Rental Income: $2549 Traditional Rental Income: $10493 Airbnb ROI: -0.77% Traditional ROI: 2.78%
2823 Janet St MATLACHA ISLES, FL Calling all renovators and bargain hunters! This fixer-upper presents a golden opportunity...	3 beds \| 3 baths \| 1,800 sq.ft.	$709,900	Airbnb cash on cash: -0.05% Traditional cash on cash: 4.04% Airbnb Rental Income: $1471 Traditional Rental Income: $3746 Airbnb ROI: -0.05% Traditional ROI: 4.04%
2652 Bridgeview St MATLACHA ISLES, FL Experience waterfront living at its finest in this charming 2-bedroom, 2-bathroom canal fr...	N/A beds \| N/A baths \| 1,158 sq.ft.	$299,900	Airbnb cash on cash: 4% Traditional cash on cash: 6.38% Airbnb Rental Income: $2276 Traditional Rental Income: $2379 Airbnb ROI: 4% Traditional ROI: 6.38%
4828 FLAMINGO Drive MATLACHA ISLES, FL Experience This Beautiful, Well-Kept 2 Bed, 2 Bath Home. This is NOT a Manufactured Home! ...	2 beds \| 2 baths \| 1,094 sq.ft.	$345,000	Airbnb cash on cash: 0.54% Traditional cash on cash: 5.48% Airbnb Rental Income: $1044 Traditional Rental Income: $2279 Airbnb ROI: 0.54% Traditional ROI: 5.48%
4819 Pine Island Rd NW MATLACHA ISLES, FL Wonderful seaside cottage with open water views! On any given day, take in the beautiful s...	2 beds \| 2 baths \| 1,056 sq.ft.	$650,000	Airbnb cash on cash: -0.57% Traditional cash on cash: 2.34% Airbnb Rental Income: $1044 Traditional Rental Income: $2447 Airbnb ROI: -0.57% Traditional ROI: 2.34%
12277 Boat Shell Dr MATLACHA ISLES, FL Discover the ultimate Gulf-access lifestyle in this beautifully renovated Key West-style w...	3 beds \| 3 baths \| 2,802 sq.ft.	$869,999	Airbnb cash on cash: -0.36% Traditional cash on cash: 3.78% Airbnb Rental Income: $1471 Traditional Rental Income: $4389 Airbnb ROI: -0.36% Traditional ROI: 3.78%
2742 Bruce St MATLACHA ISLES, FL YOUR MATLACHA WATERFRONT DREAM STARTS HERE - FULLY RENOVATED 3+DEN / 2 BATH - DIRECT GULF ...	3 beds \| 2 baths \| 1,702 sq.ft.	$464,900	Airbnb cash on cash: -0.04% Traditional cash on cash: 5.19% Airbnb Rental Income: $1471 Traditional Rental Income: $3312 Airbnb ROI: -0.04% Traditional ROI: 5.19%
2631 Bayshore Dr MATLACHA ISLES, FL Welcome to 2631 Bayshore Drive, a classic Matlacha cottage that perfectly blends Old-Flori...	3 beds \| 2 baths \| 1,326 sq.ft.	$439,000	Airbnb cash on cash: -0.44% Traditional cash on cash: 4.63% Airbnb Rental Income: $1471 Traditional Rental Income: $3120 Airbnb ROI: -0.44% Traditional ROI: 4.63%
8721 Nome Court MATLACHA ISLES, FL This 7.07-acre AG-2 zoned property with no deed restrictions has lots of potential and pri...	2 beds \| 1 baths \| 784 sq.ft.	$625,000	Airbnb cash on cash: -0.04% Traditional cash on cash: 2.29% Airbnb Rental Income: $1044 Traditional Rental Income: $2044 Airbnb ROI: -0.04% Traditional ROI: 2.29%
8677 Whispering Pines Drive MATLACHA ISLES, FL Private and peaceful 3 bed/3 bath two-story home on 1.37 acres in St. James City with a fl...	3 beds \| 3 baths \| 1,424 sq.ft.	$449,000	Airbnb cash on cash: 0.32% Traditional cash on cash: 4.29% Airbnb Rental Income: $1471 Traditional Rental Income: $2706 Airbnb ROI: 0.32% Traditional ROI: 4.29%
2686 Clyde St MATLACHA ISLES, FL This 2 br, 1 bth home located in a small quaint community of gulf access waterfront homes ...	2 beds \| 1 baths \| 855 sq.ft.	$349,000	Airbnb cash on cash: -0.52% Traditional cash on cash: 4.35% Airbnb Rental Income: $1044 Traditional Rental Income: $2278 Airbnb ROI: -0.52% Traditional ROI: 4.35%
4874 Pine Island Rd NW MATLACHA ISLES, FL TRIPLEX already generating income! Welcome to your dream waterfront escape in Matlacha, a ...	4 beds \| 3 baths \| 1,202 sq.ft.	$529,000	Airbnb cash on cash: 1.26% Traditional cash on cash: 9.04% Airbnb Rental Income: $2094 Traditional Rental Income: $5401 Airbnb ROI: 1.26% Traditional ROI: 9.04%
2859 Cheryl St MATLACHA ISLES, FL Rare waterfront opportunity in the heart of iconic Matlacha, offering a true multi-generat...	3 beds \| 2 baths \| 1,575 sq.ft.	$599,000	Airbnb cash on cash: 0.56% Traditional cash on cash: 5.33% Airbnb Rental Income: $1471 Traditional Rental Income: $3702 Airbnb ROI: 0.56% Traditional ROI: 5.33%
2647 Pine St MATLACHA ISLES, FL Discover your slice of paradise in the quiet fishing town of Matlacha Island. This charmin...	2 beds \| 1 baths \| 1,008 sq.ft.	$299,000	Airbnb cash on cash: 0.56% Traditional cash on cash: 7.12% Airbnb Rental Income: $1044 Traditional Rental Income: $2527 Airbnb ROI: 0.56% Traditional ROI: 7.12%
11476 May St MATLACHA ISLES, FL Welcome to this opportunity in the charming and colorful fishing village of Matlacha! This...	2 beds \| 2 baths \| 951 sq.ft.	$355,000	Airbnb cash on cash: -0.21% Traditional cash on cash: 5.38% Airbnb Rental Income: $1044 Traditional Rental Income: $2544 Airbnb ROI: -0.21% Traditional ROI: 5.38%
12206 Boat Shell Dr MATLACHA ISLES, FL SAILBOAT ACCESS -125' of SWFL WATERFRONT LIVING WITH A POOL Direct Gulf Access to enjoy So...	2 beds \| 1 baths \| 1,352 sq.ft.	$479,000	Airbnb cash on cash: -0.21% Traditional cash on cash: 5.04% Airbnb Rental Income: $1044 Traditional Rental Income: $3036 Airbnb ROI: -0.21% Traditional ROI: 5.04%
2701 Bruce St MATLACHA ISLES, FL Perfect Opportunity to Customize a Well Built Matlacha Home! This home sits on 100ft of de...	3 beds \| 2 baths \| 1,596 sq.ft.	$679,000	Airbnb cash on cash: -0.25% Traditional cash on cash: 4% Airbnb Rental Income: $1471 Traditional Rental Income: $3727 Airbnb ROI: -0.25% Traditional ROI: 4%
2500 Harbor View Dr MATLACHA ISLES, FL Own a Piece of Waterfront Paradise on Matlacha Island! This is a fisherman's dream just mi...	2 beds \| 1 baths \| 1,128 sq.ft.	$474,900	Airbnb cash on cash: -0.73% Traditional cash on cash: 4.25% Airbnb Rental Income: $1044 Traditional Rental Income: $2895 Airbnb ROI: -0.73% Traditional ROI: 4.25%

Matlacha-isles, FL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 61 investment properties available for sale in Matlacha-isles.

In 2026, the best neighborhood to buy investment property is MATLACHA ISLES.

The ROI for Short-Term is higher than the Long-Term in Matlacha-isles with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Matlacha Isles, FL

8642 Whispering Pines Drive

MATLACHA ISLES, FL

2 beds | 3 baths | 1,184 sq.ft.

$499,000

Airbnb cash on cash: 0.01%

Traditional cash on cash: 3.77%

Airbnb Rental Income: $1044

Traditional Rental Income: $2439

Airbnb ROI: 0.01%

Traditional ROI: 3.77%

4767 Pine Island Rd NW

MATLACHA ISLES, FL

N/A beds | N/A baths | 1,915 sq.ft.

$899,900

Airbnb cash on cash: 0.34%

Traditional cash on cash: 2.76%

Airbnb Rental Income: $2276

Traditional Rental Income: $3732

Airbnb ROI: 0.34%

Traditional ROI: 2.76%

12304 Boat Shell Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,538 sq.ft.

$849,000

Airbnb cash on cash: -0.87%

Traditional cash on cash: 1.75%

Airbnb Rental Income: $1471

Traditional Rental Income: $3106

Airbnb ROI: -0.87%

Traditional ROI: 1.75%

2504 Bayshore Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,544 sq.ft.

$550,000

Airbnb cash on cash: 0.28%

Traditional cash on cash: 4.53%

Airbnb Rental Income: $1471

Traditional Rental Income: $3220

Airbnb ROI: 0.28%

Traditional ROI: 4.53%

11859 Island Ave

MATLACHA ISLES, FL

5 beds | 4 baths | 3,615 sq.ft.

$2,000,000

Airbnb cash on cash: -0.76%

Traditional cash on cash: 0.94%

Airbnb Rental Income: $2549

Traditional Rental Income: $5083

Airbnb ROI: -0.76%

Traditional ROI: 0.94%

2589 Bayshore Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,040 sq.ft.

$434,900

Airbnb cash on cash: 0.85%

Traditional cash on cash: 3.74%

Airbnb Rental Income: $1471

Traditional Rental Income: $2217

Airbnb ROI: 0.85%

Traditional ROI: 3.74%

11828 Island Ave

MATLACHA ISLES, FL

2 beds | 2 baths | 888 sq.ft.

$399,999

Airbnb cash on cash: -0.12%

Traditional cash on cash: 4.75%

Airbnb Rental Income: $1044

Traditional Rental Income: $2506

Airbnb ROI: -0.12%

Traditional ROI: 4.75%

2864 Triggerfish St

MATLACHA ISLES, FL

N/A beds | N/A baths | 1,205 sq.ft.

$530,000

Airbnb cash on cash: 1.5%

Traditional cash on cash: 3.24%

Airbnb Rental Income: $2276

Traditional Rental Income: $2568

Airbnb ROI: 1.5%