Real Estate Investment Properties for Sale in Matlacha Isles, FL

Looking for investment property in Matlacha Isles, FL with high ROI ?

Explore a variety of short-term homes & houses in Matlacha Isles, FL. Invest wisely with VRBO & Matlacha Isles, FL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Matlacha Isles, FL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2816 Janet Street MATLACHA ISLES, FL Gulf Access Property in Matlacha with 4 Grandfathered Boat Lifts - A Boater's Dream! This ...	2 beds \| 1 baths \| 1,152 sq.ft.	$550,000	Airbnb cash on cash: -0.03% Traditional cash on cash: 0.89% Airbnb Rental Income: $2111 Traditional Rental Income: $2047 Airbnb ROI: -0.03% Traditional ROI: 0.89%
2749 Bruce Street MATLACHA ISLES, FL DREAM KITCHEN OVERLOOKING A SELF CLEANING POOL & ISLAND CANAL! Fully equipped with new wat...	3 beds \| 3 baths \| 1,524 sq.ft.	$725,000	Airbnb cash on cash: 1.77% Traditional cash on cash: 2.27% Airbnb Rental Income: $3506 Traditional Rental Income: $3069 Airbnb ROI: 1.77% Traditional ROI: 2.27%
8595 Redwood Drive MATLACHA ISLES, FL PRICED TO SELL!!! Motivated Seller, Price Reduced with an added bonus...Seller's Flood Ins...	3 beds \| 1 baths \| 1,040 sq.ft.	$341,500	Airbnb cash on cash: 6.18% Traditional cash on cash: 3.18% Airbnb Rental Income: $3506 Traditional Rental Income: $1769 Airbnb ROI: 6.18% Traditional ROI: 3.18%
2639 Bridgeview Street MATLACHA ISLES, FL Welcome to your dream waterfront escape in Matlacha, where tropical charm meets modern con...	2 beds \| 2 baths \| 1,076 sq.ft.	$457,000	Airbnb cash on cash: 1.1% Traditional cash on cash: 1.99% Airbnb Rental Income: $2111 Traditional Rental Income: $1949 Airbnb ROI: 1.1% Traditional ROI: 1.99%
8500 Redwood Drive MATLACHA ISLES, FL Paradise in paradise!!! Luxury Island living! A must see!!! Upper unit has 3 bedrooms and ...	4 beds \| 3 baths \| 2,632 sq.ft.	$599,000	Airbnb cash on cash: 4.82% Traditional cash on cash: 5.27% Airbnb Rental Income: $4278 Traditional Rental Income: $3628 Airbnb ROI: 4.82% Traditional ROI: 5.27%
2885 Triggerfish Street MATLACHA ISLES, FL Are you ready to own your own unique slice of Paradise on Matlacha? This unique home featu...	2 beds \| 2 baths \| 834 sq.ft.	$919,000	Airbnb cash on cash: -0.23% Traditional cash on cash: 1.36% Airbnb Rental Income: $2111 Traditional Rental Income: $2926 Airbnb ROI: -0.23% Traditional ROI: 1.36%
4581 Redfish Point Road MATLACHA ISLES, FL Investor-Friendly Waterfront Gem in Matlacha - Appraised at $1.1M (Sept 2024)! Welcome to ...	3 beds \| 4 baths \| 1,926 sq.ft.	$699,000	Airbnb cash on cash: 1.1% Traditional cash on cash: 1.98% Airbnb Rental Income: $3506 Traditional Rental Income: $3308 Airbnb ROI: 1.1% Traditional ROI: 1.98%
12230 Matlacha Boulevard MATLACHA ISLES, FL DIRECT SAILBOAT ACCESS - NO LOCKS, NO MISERABLE MILE! Completed in July 2024, this brand-n...	3 beds \| 2 baths \| 1,830 sq.ft.	$717,750	Airbnb cash on cash: 2.26% Traditional cash on cash: 2.87% Airbnb Rental Income: $3506 Traditional Rental Income: $3141 Airbnb ROI: 2.26% Traditional ROI: 2.87%
12262 Boat Shell Drive MATLACHA ISLES, FL Live your best island life in this beautiful fully furnished, TURNKEY direct deep-water ac...	2 beds \| 2 baths \| 1,244 sq.ft.	$549,900	Airbnb cash on cash: 0.74% Traditional cash on cash: 2.15% Airbnb Rental Income: $2111 Traditional Rental Income: $2296 Airbnb ROI: 0.74% Traditional ROI: 2.15%
2692 Clyde Street MATLACHA ISLES, FL 2 bedroom/3 bath pool home in Matlacha! The dusty work is done (drywall and tile!) and rea...	2 beds \| 3 baths \| 1,076 sq.ft.	$366,420	Airbnb cash on cash: 2.42% Traditional cash on cash: 5.5% Airbnb Rental Income: $2111 Traditional Rental Income: $2630 Airbnb ROI: 2.42% Traditional ROI: 5.5%
2761 Geary Street MATLACHA ISLES, FL BEST PRICED ELEVATED HOME ON THIS ISLAND AND IS A CURRENTLY INCOME-PRODUCING VACATION RENT...	2 beds \| 2 baths \| 1,295 sq.ft.	$650,000	Airbnb cash on cash: 0.36% Traditional cash on cash: 1.79% Airbnb Rental Income: $2111 Traditional Rental Income: $2441 Airbnb ROI: 0.36% Traditional ROI: 1.79%
5225 Anchorage Drive MATLACHA ISLES, FL Welcome to your private oasis on Pine Island! This beautifully maintained 3-bed, 2-bath CB...	3 beds \| 2 baths \| 1,621 sq.ft.	$450,000	Airbnb cash on cash: 4.31% Traditional cash on cash: 4.02% Airbnb Rental Income: $3506 Traditional Rental Income: $2610 Airbnb ROI: 4.31% Traditional ROI: 4.02%
12101 Moon Shell Drive MATLACHA ISLES, FL DIRECT GULF ACCESS!!! Located on an oversized cul-de-sac lot with approximately 104 feet o...	2 beds \| 2 baths \| 1,312 sq.ft.	$499,900	Airbnb cash on cash: 1.09% Traditional cash on cash: 2.92% Airbnb Rental Income: $2111 Traditional Rental Income: $2424 Airbnb ROI: 1.09% Traditional ROI: 2.92%
8625 Redwood Drive MATLACHA ISLES, FL Discover relaxed island living in this charming three-bedroom, two-bath stilt home in St. ...	3 beds \| 2 baths \| 1,377 sq.ft.	$425,000	Airbnb cash on cash: 5.36% Traditional cash on cash: 6.77% Airbnb Rental Income: $3506 Traditional Rental Income: $3295 Airbnb ROI: 5.36% Traditional ROI: 6.77%
5166 Sitka Drive MATLACHA ISLES, FL POOL HOME ON OVER 1/2 AN ACRE CORNER LOT!!! This home was built in 2023 and is in "like ne...	3 beds \| 2 baths \| 1,440 sq.ft.	$422,900	Airbnb cash on cash: 5.48% Traditional cash on cash: 4.8% Airbnb Rental Income: $3506 Traditional Rental Income: $2466 Airbnb ROI: 5.48% Traditional ROI: 4.8%
2595 Pine Street MATLACHA ISLES, FL You have to see this unique opportunity! WITH TRANSFERABLE FLOOD INSURANCE!! This versatil...	2 beds \| 2 baths \| 824 sq.ft.	$282,000	Airbnb cash on cash: 3.51% Traditional cash on cash: 5.84% Airbnb Rental Income: $2111 Traditional Rental Income: $2188 Airbnb ROI: 3.51% Traditional ROI: 5.84%
4760 Pine Island Road NW MATLACHA ISLES, FL Here is your chance to own a slice of waterfront paradise in the historic area of Matlacha...	4 beds \| 4 baths \| 1,284 sq.ft.	$700,000	Airbnb cash on cash: 3.06% Traditional cash on cash: 2.67% Airbnb Rental Income: $4278 Traditional Rental Income: $3121 Airbnb ROI: 3.06% Traditional ROI: 2.67%
12201 Shoreview Drive MATLACHA ISLES, FL This property sits high and never had any flood water damage from past 3 hurricanes so its...	5 beds \| 5 baths \| 4,021 sq.ft.	$2,900,000	Airbnb cash on cash: -0.16% Traditional cash on cash: 0.71% Airbnb Rental Income: $4973 Traditional Rental Income: $6302 Airbnb ROI: -0.16% Traditional ROI: 0.71%
4828 Flamingo Drive MATLACHA ISLES, FL This is a very beautiful well kept custom built home; not a manufactured home. It has an o...	2 beds \| 2 baths \| 1,094 sq.ft.	$340,000	Airbnb cash on cash: 2.94% Traditional cash on cash: 4.01% Airbnb Rental Income: $2111 Traditional Rental Income: $1912 Airbnb ROI: 2.94% Traditional ROI: 4.01%
5099 Flamingo Drive MATLACHA ISLES, FL Water access home that was damaged by the hurricanes. Possible repair or start fresh with ...	1 beds \| 3 baths \| 576 sq.ft.	$99,000	Airbnb cash on cash: 9.48% Traditional cash on cash: 11.86% Airbnb Rental Income: $1657 Traditional Rental Income: $1422 Airbnb ROI: 9.48% Traditional ROI: 11.86%
4998 Curlew Drive MATLACHA ISLES, FL POSSIBLE SELLER FINANCE NO HURRICAN DAMAGE NEVER FLOODED {{Enjoy watching osprey, eagles, ...	2 beds \| 2 baths \| 920 sq.ft.	$187,000	Airbnb cash on cash: 6.4% Traditional cash on cash: 7.72% Airbnb Rental Income: $2111 Traditional Rental Income: $1806 Airbnb ROI: 6.4% Traditional ROI: 7.72%
4819 Pine Island Road NW MATLACHA ISLES, FL Wonderful seaside cottage with open water views! On any given day, take in the beautiful s...	2 beds \| 2 baths \| 1,056 sq.ft.	$675,000	Airbnb cash on cash: 0.83% Traditional cash on cash: 1.66% Airbnb Rental Income: $2111 Traditional Rental Income: $2098 Airbnb ROI: 0.83% Traditional ROI: 1.66%
2610 Pine Street MATLACHA ISLES, FL Adorable Matlacha cottage on the water nestled just steps away from the heart of the islan...	1 beds \| 1 baths \| 708 sq.ft.	$249,698	Airbnb cash on cash: 3.32% Traditional cash on cash: 5.66% Airbnb Rental Income: $1657 Traditional Rental Income: $1744 Airbnb ROI: 3.32% Traditional ROI: 5.66%
2631 Bayshore Drive MATLACHA ISLES, FL Charming Waterfront Home in Matlacha. Seize the chance to own a breathtaking corner waterf...	3 beds \| 2 baths \| 1,326 sq.ft.	$485,000	Airbnb cash on cash: 3.19% Traditional cash on cash: 3.32% Airbnb Rental Income: $3506 Traditional Rental Income: $2789 Airbnb ROI: 3.19% Traditional ROI: 3.32%
2839 Janet Street MATLACHA ISLES, FL Step into a slice of Old Florida charm with this beautifully updated island cottage nestle...	2 beds \| 2 baths \| 1,001 sq.ft.	$449,900	Airbnb cash on cash: 1.84% Traditional cash on cash: 2.98% Airbnb Rental Income: $2111 Traditional Rental Income: $2050 Airbnb ROI: 1.84% Traditional ROI: 2.98%
8721 Nome Court MATLACHA ISLES, FL This 7.07-acre AG-2 zoned property with no deed restrictions has lots of potential and pri...	2 beds \| 1 baths \| 784 sq.ft.	$599,000	Airbnb cash on cash: 1.59% Traditional cash on cash: 1.88% Airbnb Rental Income: $2111 Traditional Rental Income: $1734 Airbnb ROI: 1.59% Traditional ROI: 1.88%
8545 Redwood Drive MATLACHA ISLES, FL Back on the market, don't miss this second chance to make it yours! Motivated Seller, Pric...	2 beds \| 3 baths \| 1,075 sq.ft.	$359,500	Airbnb cash on cash: 2.77% Traditional cash on cash: 4.53% Airbnb Rental Income: $2111 Traditional Rental Income: $2176 Airbnb ROI: 2.77% Traditional ROI: 4.53%
2821 Bruce Street MATLACHA ISLES, FL Completely Renovated 3/2 Deep Water Access with Pool in Matlacha! Move right in, NO work n...	3 beds \| 2 baths \| 1,368 sq.ft.	$545,000	Airbnb cash on cash: 3.25% Traditional cash on cash: 2.85% Airbnb Rental Income: $3506 Traditional Rental Income: $2533 Airbnb ROI: 3.25% Traditional ROI: 2.85%
4706 Pine Island Road NW MATLACHA ISLES, FL Waterfront Paradise in Historic Matlacha Nestled in the heart of historic Matlacha, this c...	2 beds \| 2 baths \| 938 sq.ft.	$975,000	Airbnb cash on cash: 0.44% Traditional cash on cash: 0.81% Airbnb Rental Income: $2111 Traditional Rental Income: $1906 Airbnb ROI: 0.44% Traditional ROI: 0.81%
4741/4743 Pine Island Road NW MATLACHA ISLES, FL An incredible waterfront investment opportunity awaits in the heart of historic Matlacha -...	3 beds \| 4 baths \| 2,896 sq.ft.	$599,999	Airbnb cash on cash: 2.68% Traditional cash on cash: 5.83% Airbnb Rental Income: $3506 Traditional Rental Income: $4498 Airbnb ROI: 2.68% Traditional ROI: 5.83%
11940 Island Avenue MATLACHA ISLES, FL Welcome to this beautifully updated stilt home in the charming coastal community of Matlac...	3 beds \| 3 baths \| 2,313 sq.ft.	$1,199,000	Airbnb cash on cash: 0.43% Traditional cash on cash: 0.86% Airbnb Rental Income: $3506 Traditional Rental Income: $3209 Airbnb ROI: 0.43% Traditional ROI: 0.86%
8677 WHISPERING PINES DRIVE MATLACHA ISLES, FL Embrace the laid-back island lifestyle with this charming two-story home, perfectly situat...	3 beds \| 3 baths \| 2,544 sq.ft.	$499,000	Airbnb cash on cash: 3.86% Traditional cash on cash: 6.07% Airbnb Rental Income: $3506 Traditional Rental Income: $3765 Airbnb ROI: 3.86% Traditional ROI: 6.07%
2686 Clyde Street MATLACHA ISLES, FL This 2 br, 1 bth home located in a small quaint community of gulf access waterfront homes ...	2 beds \| 1 baths \| 855 sq.ft.	$372,000	Airbnb cash on cash: 2% Traditional cash on cash: 2.68% Airbnb Rental Income: $2111 Traditional Rental Income: $1811 Airbnb ROI: 2% Traditional ROI: 2.68%
4874 Pine Island Road NW MATLACHA ISLES, FL THE LIST PRICE REPRESENTS THE OPENING OFFER AMOUNT. AGENTS - PLEASE VIEW REALTOR REMARKS I...	4 beds \| 3 baths \| N/A	$450,000	Airbnb cash on cash: 5.97% Traditional cash on cash: 8.66% Airbnb Rental Income: $4278 Traditional Rental Income: $4507 Airbnb ROI: 5.97% Traditional ROI: 8.66%
2591 Cay Cove MATLACHA ISLES, FL Your Dream Oasis Awaits on Matlacha Island!** Less than a lot on the island and it has a $...	2 beds \| 2 baths \| 800 sq.ft.	$369,713	Airbnb cash on cash: 2.24% Traditional cash on cash: 3.15% Airbnb Rental Income: $2111 Traditional Rental Income: $1886 Airbnb ROI: 2.24% Traditional ROI: 3.15%
2669 Coco Plum Drive MATLACHA ISLES, FL Island living with unforgettable sunsets! Completely remodeled with marvelous style, this ...	2 beds \| 2 baths \| 1,533 sq.ft.	$520,000	Airbnb cash on cash: 1.34% Traditional cash on cash: 3.88% Airbnb Rental Income: $2111 Traditional Rental Income: $2803 Airbnb ROI: 1.34% Traditional ROI: 3.88%
2859 Cheryl Street MATLACHA ISLES, FL WHETHER YOU'RE LOOKING FOR A SAVVY INVESTMENT PROPERTY OR A PERSONAL WATERFRONT RETREAT, T...	3 beds \| 2 baths \| N/A	$664,900	Airbnb cash on cash: 3.15% Traditional cash on cash: 3.11% Airbnb Rental Income: $3506 Traditional Rental Income: $2703 Airbnb ROI: 3.15% Traditional ROI: 3.11%
2602 Pine Street MATLACHA ISLES, FL Seller financing available with 30% down 12% interest, with a balloon in 12 months!!! Char...	1 beds \| 1 baths \| 828 sq.ft.	$189,900	Airbnb cash on cash: 2.89% Traditional cash on cash: 5.21% Airbnb Rental Income: $1657 Traditional Rental Income: $1610 Airbnb ROI: 2.89% Traditional ROI: 5.21%
11915 Island Avenue MATLACHA ISLES, FL Searching for a stunning bay view with a forever-protected, unobstructed 146' panorama vie...	3 beds \| 2 baths \| 2,218 sq.ft.	$970,000	Airbnb cash on cash: 1.25% Traditional cash on cash: 1.94% Airbnb Rental Income: $3506 Traditional Rental Income: $3351 Airbnb ROI: 1.25% Traditional ROI: 1.94%
17638 Corallina Drive MATLACHA ISLES, FL Discover island charm and waterfront luxury in this boater's paradise, perfectly located j...	3 beds \| 3 baths \| 1,496 sq.ft.	$530,000	Airbnb cash on cash: 3.7% Traditional cash on cash: 3.87% Airbnb Rental Income: $3506 Traditional Rental Income: $2816 Airbnb ROI: 3.7% Traditional ROI: 3.87%

Real Estate investment in Matlacha-isles, FL

There are 59 properties for sale in the city of Matlacha Isles . The median list price in Matlacha Isles is $499,900 and the average price per square foot is $364. In September 2025, the average monthly cash on cash return in Matlacha Isles is 3.00%. The average monthly rental income in Matlacha Isles is $2,483.

Matlacha-isles, FL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 59 investment properties available for sale in Matlacha-isles.

In 2025, the best neighborhood to buy investment property is MATLACHA ISLES.

The ROI for Long-Term is higher than the Short-Term in Matlacha-isles with average rental income of $2,483.

Your search for investment property begins and ends here

Investment Property for Sale in Matlacha Isles, FL

2816 Janet Street

MATLACHA ISLES, FL

2 beds | 1 baths | 1,152 sq.ft.

$550,000

Airbnb cash on cash: -0.03%

Traditional cash on cash: 0.89%

Airbnb Rental Income: $2111

Traditional Rental Income: $2047

Airbnb ROI: -0.03%

Traditional ROI: 0.89%

2749 Bruce Street

MATLACHA ISLES, FL

3 beds | 3 baths | 1,524 sq.ft.

$725,000

Airbnb cash on cash: 1.77%

Traditional cash on cash: 2.27%

Airbnb Rental Income: $3506

Traditional Rental Income: $3069

Airbnb ROI: 1.77%

Traditional ROI: 2.27%

8595 Redwood Drive

MATLACHA ISLES, FL

3 beds | 1 baths | 1,040 sq.ft.

$341,500

Airbnb cash on cash: 6.18%

Traditional cash on cash: 3.18%

Airbnb Rental Income: $3506

Traditional Rental Income: $1769

Airbnb ROI: 6.18%

Traditional ROI: 3.18%

2639 Bridgeview Street

MATLACHA ISLES, FL

2 beds | 2 baths | 1,076 sq.ft.

$457,000

Airbnb cash on cash: 1.1%

Traditional cash on cash: 1.99%

Airbnb Rental Income: $2111

Traditional Rental Income: $1949

Airbnb ROI: 1.1%

Traditional ROI: 1.99%

8500 Redwood Drive

MATLACHA ISLES, FL

4 beds | 3 baths | 2,632 sq.ft.

$599,000

Airbnb cash on cash: 4.82%

Traditional cash on cash: 5.27%

Airbnb Rental Income: $4278

Traditional Rental Income: $3628

Airbnb ROI: 4.82%

Traditional ROI: 5.27%

2885 Triggerfish Street

MATLACHA ISLES, FL

2 beds | 2 baths | 834 sq.ft.

$919,000

Airbnb cash on cash: -0.23%

Traditional cash on cash: 1.36%

Airbnb Rental Income: $2111

Traditional Rental Income: $2926

Airbnb ROI: -0.23%

Traditional ROI: 1.36%

4581 Redfish Point Road

MATLACHA ISLES, FL

3 beds | 4 baths | 1,926 sq.ft.

$699,000

Airbnb cash on cash: 1.1%

Traditional cash on cash: 1.98%

Airbnb Rental Income: $3506

Traditional Rental Income: $3308

Airbnb ROI: 1.1%

Traditional ROI: 1.98%

12230 Matlacha Boulevard

MATLACHA ISLES, FL

3 beds | 2 baths | 1,830 sq.ft.

$717,750

Airbnb cash on cash: 2.26%

Traditional cash on cash: 2.87%

Airbnb Rental Income: $3506

Traditional Rental Income: $3141

Airbnb ROI: 2.26%