Real Estate Investment Properties for Sale in Matlacha Isles, FL

Looking for investment property in Matlacha Isles, FL with high ROI ?

Explore a variety of short-term homes & houses in Matlacha Isles, FL. Invest wisely with VRBO & Matlacha Isles, FL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Matlacha Isles, FL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
8642 Whispering Pines Drive MATLACHA ISLES, FL Live the dream on a Southwest Florida island! Nestled on beautiful Pine Island-just 2 mile...	2 beds \| 3 baths \| 1,184 sq.ft.	$499,000	Airbnb cash on cash: -0.4% Traditional cash on cash: 3.77% Airbnb Rental Income: $814 Traditional Rental Income: $2439 Airbnb ROI: -0.4% Traditional ROI: 3.77%
4767 Pine Island Road NW MATLACHA ISLES, FL Do not miss this one-of-a-kind Matlacha property! This 3-bedroom, 3-bath home sits on over...	3 beds \| 3 baths \| 1,915 sq.ft.	$1,250,000	Airbnb cash on cash: -0.8% Traditional cash on cash: 1.71% Airbnb Rental Income: $1204 Traditional Rental Income: $3732 Airbnb ROI: -0.8% Traditional ROI: 1.71%
12304 BOAT SHELL DRIVE MATLACHA ISLES, FL Discover a true waterfront escape in unincorporated Matlacha Isles where quiet island livi...	3 beds \| 3 baths \| 1,538 sq.ft.	$849,000	Airbnb cash on cash: -1.15% Traditional cash on cash: 1.75% Airbnb Rental Income: $1204 Traditional Rental Income: $3106 Airbnb ROI: -1.15% Traditional ROI: 1.75%
2504 Bayshore Drive MATLACHA ISLES, FL MAJOR PRICE REDUCTION!!!! Rare Bay front Opportunity: Move-In Ready with Unrivaled Views. ...	2 beds \| 2 baths \| 1,544 sq.ft.	$575,000	Airbnb cash on cash: -0.8% Traditional cash on cash: 4.29% Airbnb Rental Income: $814 Traditional Rental Income: $3220 Airbnb ROI: -0.8% Traditional ROI: 4.29%
2589 Bayshore Drive MATLACHA ISLES, FL Live Your Best Island Life in this Beautiful Direct Deep-Water Access Island Home! Surroun...	3 beds \| 2 baths \| 1,040 sq.ft.	$434,900	Airbnb cash on cash: 0.3% Traditional cash on cash: 3.74% Airbnb Rental Income: $1204 Traditional Rental Income: $2217 Airbnb ROI: 0.3% Traditional ROI: 3.74%
11828 Island Avenue MATLACHA ISLES, FL Waterfront living at its best in the heart of Matlacha! This fully turnkey, 2-bedroom, 2-b...	2 beds \| 2 baths \| 888 sq.ft.	$468,000	Airbnb cash on cash: -0.68% Traditional cash on cash: 3.92% Airbnb Rental Income: $814 Traditional Rental Income: $2506 Airbnb ROI: -0.68% Traditional ROI: 3.92%
2743 JANET STREET MATLACHA ISLES, FL Direct Gulf access with panoramic bay views and protected canal docking in the heart of Ma...	4 beds \| 3 baths \| 2,248 sq.ft.	$1,075,000	Airbnb cash on cash: -1.23% Traditional cash on cash: 1.79% Airbnb Rental Income: $1147 Traditional Rental Income: $3786 Airbnb ROI: -1.23% Traditional ROI: 1.79%
12234 Boat Shell Drive MATLACHA ISLES, FL Calling all boaters and island lifestyle buyers. Welcome to a true waterfront island retre...	3 beds \| 2 baths \| 1,960 sq.ft.	$874,900	Airbnb cash on cash: -0.99% Traditional cash on cash: 2.34% Airbnb Rental Income: $1204 Traditional Rental Income: $3526 Airbnb ROI: -0.99% Traditional ROI: 2.34%
2849 Triggerfish St MATLACHA ISLES, FL ATTENTION INVESTORS, BUILDERS AND SAVVY HOMEOWNERS! Old Florida Garden Style Duplex sited...	N/A beds \| N/A baths \| N/A	$599,900	Airbnb cash on cash: -1.31% Traditional cash on cash: 2.44% Airbnb Rental Income: $557 Traditional Rental Income: $2371 Airbnb ROI: -1.31% Traditional ROI: 2.44%
2639 Bridgeview Street MATLACHA ISLES, FL Welcome to your dream waterfront escape in Matlacha, where tropical charm meets modern con...	2 beds \| 2 baths \| 1,076 sq.ft.	$649,500	Airbnb cash on cash: -0.96% Traditional cash on cash: 1.45% Airbnb Rental Income: $814 Traditional Rental Income: $1949 Airbnb ROI: -0.96% Traditional ROI: 1.45%
8500 REDWOOD DRIVE MATLACHA ISLES, FL Luxury Island Living!!! This gem includes a 1-year home warranty, $5,000 toward your firs...	4 beds \| 3 baths \| 2,632 sq.ft.	$599,000	Airbnb cash on cash: 0.15% Traditional cash on cash: 5.9% Airbnb Rental Income: $1147 Traditional Rental Income: $3986 Airbnb ROI: 0.15% Traditional ROI: 5.9%
12139 Matlacha Boulevard MATLACHA ISLES, FL This meticulously upgraded home has undergone a remarkable transformation since its purcha...	3 beds \| 4 baths \| 1,718 sq.ft.	$565,000	Airbnb cash on cash: -0.7% Traditional cash on cash: 4.69% Airbnb Rental Income: $1204 Traditional Rental Income: $3657 Airbnb ROI: -0.7% Traditional ROI: 4.69%
12230 Matlacha Boulevard MATLACHA ISLES, FL DIRECT SAILBOAT ACCESS - NO LOCKS, NO MISERABLE MILE! Completed in July 2024, this brand-n...	3 beds \| 2 baths \| 1,830 sq.ft.	$599,900	Airbnb cash on cash: -0.53% Traditional cash on cash: 5.19% Airbnb Rental Income: $1204 Traditional Rental Income: $4015 Airbnb ROI: -0.53% Traditional ROI: 5.19%
12262 Boat Shell Drive MATLACHA ISLES, FL HUGE PRICE REDUCTION!!!!! TURNKEY READY TO MOVE IN ISLAND HOME IN SOUTHWEST FLORIDA! Live ...	2 beds \| 2 baths \| 1,244 sq.ft.	$449,500	Airbnb cash on cash: -1.44% Traditional cash on cash: 4.14% Airbnb Rental Income: $814 Traditional Rental Income: $2840 Airbnb ROI: -1.44% Traditional ROI: 4.14%
2761 Geary Street MATLACHA ISLES, FL SELLER IS MOTIVATED AND YOU NEED TO MAKE THIS HOME YOURS! Make this established vacation r...	2 beds \| 2 baths \| 1,295 sq.ft.	$650,000	Airbnb cash on cash: -1.29% Traditional cash on cash: 2.19% Airbnb Rental Income: $814 Traditional Rental Income: $2602 Airbnb ROI: -1.29% Traditional ROI: 2.19%
4882 WOODSTOCK Road MATLACHA ISLES, FL *Exclusive Luxury Farm for Sale* Welcome to paradise and the property of your dreams. ...	3 beds \| 3 baths \| 1,816 sq.ft.	$980,000	Airbnb cash on cash: -0.57% Traditional cash on cash: 2.25% Airbnb Rental Income: $1204 Traditional Rental Income: $3385 Airbnb ROI: -0.57% Traditional ROI: 2.25%
9419 Treasure Lake Court MATLACHA ISLES, FL Lovely spacious pool home in gated community of Island Acres. Beautifully landscaped, and ...	3 beds \| 3 baths \| 2,270 sq.ft.	$535,000	Airbnb cash on cash: -0.85% Traditional cash on cash: 5.69% Airbnb Rental Income: $1204 Traditional Rental Income: $4089 Airbnb ROI: -0.85% Traditional ROI: 5.69%
11599 Island Avenue MATLACHA ISLES, FL Experience premier waterfront luxury in this impeccably renovated 2-bed, 2-bath coastal sa...	2 beds \| 2 baths \| 1,715 sq.ft.	$995,000	Airbnb cash on cash: -1.08% Traditional cash on cash: 2.41% Airbnb Rental Income: $814 Traditional Rental Income: $3723 Airbnb ROI: -1.08% Traditional ROI: 2.41%
12101 Moon Shell Drive MATLACHA ISLES, FL DIRECT GULF ACCESS!!! Located on an oversized cul-de-sac lot with approximately 104 feet o...	2 beds \| 2 baths \| 1,312 sq.ft.	$499,900	Airbnb cash on cash: -1.22% Traditional cash on cash: 3.78% Airbnb Rental Income: $814 Traditional Rental Income: $2827 Airbnb ROI: -1.22% Traditional ROI: 3.78%
12065 Boat Shell Drive MATLACHA ISLES, FL AMAZING PRICE for this beautifully remodeled 3-bedroom, 2-bathroom home located in the des...	3 beds \| 2 baths \| 1,054 sq.ft.	$500,000	Airbnb cash on cash: -1.34% Traditional cash on cash: 3.02% Airbnb Rental Income: $1204 Traditional Rental Income: $2855 Airbnb ROI: -1.34% Traditional ROI: 3.02%
12196 Matlacha Boulevard MATLACHA ISLES, FL Calling all boaters, investors and anyone who wants to live the island life! This is more ...	3 beds \| 2 baths \| 1,935 sq.ft.	$595,000	Airbnb cash on cash: -1.26% Traditional cash on cash: 4.4% Airbnb Rental Income: $1204 Traditional Rental Income: $3959 Airbnb ROI: -1.26% Traditional ROI: 4.4%
2649 Coco Plum Drive MATLACHA ISLES, FL Welcome to your slice of paradise in the heart of Matlacha! This beautifully remodeled 2-b...	1 beds \| 1 baths \| 640 sq.ft.	$334,000	Airbnb cash on cash: -1.73% Traditional cash on cash: 4% Airbnb Rental Income: $409 Traditional Rental Income: $1950 Airbnb ROI: -1.73% Traditional ROI: 4%
2595 Pine Street MATLACHA ISLES, FL You have to see this unique opportunity! WITH TRANSFERABLE FLOOD INSURANCE!! This versatil...	2 beds \| 2 baths \| 824 sq.ft.	$266,000	Airbnb cash on cash: -0.53% Traditional cash on cash: 7.37% Airbnb Rental Income: $814 Traditional Rental Income: $2470 Airbnb ROI: -0.53% Traditional ROI: 7.37%
4760 Pine Island Road NW MATLACHA ISLES, FL Here is your chance to own a slice of waterfront paradise in the historic area of Matlacha...	4 beds \| 4 baths \| 1,284 sq.ft.	$568,000	Airbnb cash on cash: -0.93% Traditional cash on cash: 9.71% Airbnb Rental Income: $1147 Traditional Rental Income: $6407 Airbnb ROI: -0.93% Traditional ROI: 9.71%
12201 Shoreview Drive MATLACHA ISLES, FL Stunning waterfront estate set on 2.24 acres in the heart of Matlacha-truly a boater's par...	5 beds \| 5 baths \| 4,021 sq.ft.	$2,598,000	Airbnb cash on cash: -1.27% Traditional cash on cash: 2.78% Airbnb Rental Income: $1123 Traditional Rental Income: $10493 Airbnb ROI: -1.27% Traditional ROI: 2.78%
2823 Janet St MATLACHA ISLES, FL Calling all renovators and bargain hunters! This fixer-upper presents a golden opportunity...	3 beds \| 3 baths \| 1,800 sq.ft.	$734,900	Airbnb cash on cash: -0.41% Traditional cash on cash: 3.87% Airbnb Rental Income: $1204 Traditional Rental Income: $3746 Airbnb ROI: -0.41% Traditional ROI: 3.87%
2634 Coco Plum Drive MATLACHA ISLES, FL REDUCED $25K! NO FLOODING from any previous hurricanes! OWNER financing available This...	2 beds \| 2 baths \| 864 sq.ft.	$299,900	Airbnb cash on cash: -0.45% Traditional cash on cash: 5.81% Airbnb Rental Income: $814 Traditional Rental Income: $2257 Airbnb ROI: -0.45% Traditional ROI: 5.81%
4828 FLAMINGO Drive MATLACHA ISLES, FL Experience This Beautiful, Well-Kept 2 Bed, 2 Bath Home. This is NOT a Manufactured Home! ...	2 beds \| 2 baths \| 1,094 sq.ft.	$345,000	Airbnb cash on cash: -0.05% Traditional cash on cash: 5.48% Airbnb Rental Income: $814 Traditional Rental Income: $2279 Airbnb ROI: -0.05% Traditional ROI: 5.48%
4819 Pine Island Road NW MATLACHA ISLES, FL Wonderful seaside cottage with open water views! On any given day, take in the beautiful s...	2 beds \| 2 baths \| 1,056 sq.ft.	$650,000	Airbnb cash on cash: -0.89% Traditional cash on cash: 2.34% Airbnb Rental Income: $814 Traditional Rental Income: $2447 Airbnb ROI: -0.89% Traditional ROI: 2.34%
2822 Bruce St MATLACHA ISLES, FL Waterfront Island Paradise - Direct Gulf Access, No Bridges! Welcome to your "MOVE IN READ...	2 beds \| 1 baths \| 827 sq.ft.	$414,000	Airbnb cash on cash: -0.59% Traditional cash on cash: 4.14% Airbnb Rental Income: $814 Traditional Rental Income: $2324 Airbnb ROI: -0.59% Traditional ROI: 4.14%
12277 Boat Shell Dr MATLACHA ISLES, FL Direct Gulf-access waterfront home in desirable Matlacha Isles! This recently renovated, c...	3 beds \| 3 baths \| 2,802 sq.ft.	$949,999	Airbnb cash on cash: -0.67% Traditional cash on cash: 3.38% Airbnb Rental Income: $1204 Traditional Rental Income: $4389 Airbnb ROI: -0.67% Traditional ROI: 3.38%
2742 Bruce Street MATLACHA ISLES, FL YOUR MATLACHA WATERFRONT DREAM STARTS HERE - FULLY RENOVATED 3+DEN / 2 BATH - DIRECT GULF ...	3 beds \| 2 baths \| 1,702 sq.ft.	$464,900	Airbnb cash on cash: -0.55% Traditional cash on cash: 5.19% Airbnb Rental Income: $1204 Traditional Rental Income: $3312 Airbnb ROI: -0.55% Traditional ROI: 5.19%
2631 Bayshore Drive MATLACHA ISLES, FL Welcome to 2631 Bayshore Drive, a classic Matlacha cottage that perfectly blends Old-Flori...	3 beds \| 2 baths \| 1,326 sq.ft.	$439,000	Airbnb cash on cash: -0.98% Traditional cash on cash: 4.63% Airbnb Rental Income: $1204 Traditional Rental Income: $3120 Airbnb ROI: -0.98% Traditional ROI: 4.63%
2556 Cay Cove MATLACHA ISLES, FL Welcome to your own slice of paradise in the vibrant waterfront community of Matlacha on P...	2 beds \| 1 baths \| 884 sq.ft.	$459,000	Airbnb cash on cash: -1.07% Traditional cash on cash: 3.17% Airbnb Rental Income: $814 Traditional Rental Income: $2313 Airbnb ROI: -1.07% Traditional ROI: 3.17%
8721 Nome Court MATLACHA ISLES, FL This 7.07-acre AG-2 zoned property with no deed restrictions has lots of potential and pri...	2 beds \| 1 baths \| 784 sq.ft.	$599,000	Airbnb cash on cash: -0.35% Traditional cash on cash: 2.43% Airbnb Rental Income: $814 Traditional Rental Income: $2044 Airbnb ROI: -0.35% Traditional ROI: 2.43%
4736 Pine Island Road NW MATLACHA ISLES, FL Enjoy the breathtaking sunset views from this amazing Matlacha property. Its's all about l...	2 beds \| 2 baths \| 1,232 sq.ft.	$350,000	Airbnb cash on cash: 0.11% Traditional cash on cash: 9.74% Airbnb Rental Income: $814 Traditional Rental Income: $3655 Airbnb ROI: 0.11% Traditional ROI: 9.74%
11242 Matlacha Avenue MATLACHA ISLES, FL This charming home in the picturesque town of Matlacha is just footsteps away from the his...	1 beds \| 1 baths \| 480 sq.ft.	$400,000	Airbnb cash on cash: -1.85% Traditional cash on cash: 2.37% Airbnb Rental Income: $409 Traditional Rental Income: $1738 Airbnb ROI: -1.85% Traditional ROI: 2.37%
2629 Coco Plum Drive MATLACHA ISLES, FL Price Adjustment - Adjacent Lot Now Included! Island Living Starts Here - Waterfront Gem i...	1 beds \| 1 baths \| 558 sq.ft.	$299,000	Airbnb cash on cash: -1.37% Traditional cash on cash: 4.96% Airbnb Rental Income: $409 Traditional Rental Income: $1935 Airbnb ROI: -1.37% Traditional ROI: 4.96%
2821 Bruce Street MATLACHA ISLES, FL Offering sophisticated improvements that go beyond standard upgrades, here is the BEST hom...	3 beds \| 2 baths \| 1,698 sq.ft.	$530,000	Airbnb cash on cash: -0.02% Traditional cash on cash: 5.53% Airbnb Rental Income: $1204 Traditional Rental Income: $3564 Airbnb ROI: -0.02% Traditional ROI: 5.53%
2480 Bayshore Drive MATLACHA ISLES, FL Experience the best of the Southwest Florida lifestyle in this luxuriously upgraded waterf...	3 beds \| 2 baths \| 1,383 sq.ft.	$624,500	Airbnb cash on cash: -0.52% Traditional cash on cash: 3.66% Airbnb Rental Income: $1204 Traditional Rental Income: $3249 Airbnb ROI: -0.52% Traditional ROI: 3.66%

Real Estate investment in Matlacha-isles, FL

There are 61 properties for sale in the city of Matlacha Isles . The median list price in Matlacha Isles is $535,000 and the average price per square foot is $336. In April 2026, the average monthly cash on cash return in Matlacha Isles is 4.00%. The average monthly rental income in Matlacha Isles is $2,931.

Matlacha-isles, FL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 61 investment properties available for sale in Matlacha-isles.

In 2026, the best neighborhood to buy investment property is MATLACHA ISLES.

The ROI for Long-Term is higher than the Short-Term in Matlacha-isles with average rental income of $2,931.

Your search for investment property begins and ends here

Investment Property for Sale in Matlacha Isles, FL

8642 Whispering Pines Drive

MATLACHA ISLES, FL

2 beds | 3 baths | 1,184 sq.ft.

$499,000

Airbnb cash on cash: -0.4%

Traditional cash on cash: 3.77%

Airbnb Rental Income: $814

Traditional Rental Income: $2439

Airbnb ROI: -0.4%

Traditional ROI: 3.77%

4767 Pine Island Road NW

MATLACHA ISLES, FL

3 beds | 3 baths | 1,915 sq.ft.

$1,250,000

Airbnb cash on cash: -0.8%

Traditional cash on cash: 1.71%

Airbnb Rental Income: $1204

Traditional Rental Income: $3732

Airbnb ROI: -0.8%

Traditional ROI: 1.71%

12304 BOAT SHELL DRIVE

MATLACHA ISLES, FL

3 beds | 3 baths | 1,538 sq.ft.

$849,000

Airbnb cash on cash: -1.15%

Traditional cash on cash: 1.75%

Airbnb Rental Income: $1204

Traditional Rental Income: $3106

Airbnb ROI: -1.15%

Traditional ROI: 1.75%

2504 Bayshore Drive

MATLACHA ISLES, FL

2 beds | 2 baths | 1,544 sq.ft.

$575,000

Airbnb cash on cash: -0.8%

Traditional cash on cash: 4.29%

Airbnb Rental Income: $814

Traditional Rental Income: $3220

Airbnb ROI: -0.8%

Traditional ROI: 4.29%

2589 Bayshore Drive

MATLACHA ISLES, FL

3 beds | 2 baths | 1,040 sq.ft.

$434,900

Airbnb cash on cash: 0.3%

Traditional cash on cash: 3.74%

Airbnb Rental Income: $1204

Traditional Rental Income: $2217

Airbnb ROI: 0.3%

Traditional ROI: 3.74%

11828 Island Avenue

MATLACHA ISLES, FL

2 beds | 2 baths | 888 sq.ft.

$468,000

Airbnb cash on cash: -0.68%

Traditional cash on cash: 3.92%

Airbnb Rental Income: $814

Traditional Rental Income: $2506

Airbnb ROI: -0.68%

Traditional ROI: 3.92%

2743 JANET STREET

MATLACHA ISLES, FL

4 beds | 3 baths | 2,248 sq.ft.

$1,075,000

Airbnb cash on cash: -1.23%

Traditional cash on cash: 1.79%

Airbnb Rental Income: $1147

Traditional Rental Income: $3786

Airbnb ROI: -1.23%

Traditional ROI: 1.79%

12234 Boat Shell Drive

MATLACHA ISLES, FL

3 beds | 2 baths | 1,960 sq.ft.

$874,900

Airbnb cash on cash: -0.99%

Traditional cash on cash: 2.34%

Airbnb Rental Income: $1204

Traditional Rental Income: $3526

Airbnb ROI: -0.99%