Real Estate Investment Properties for Sale in Matlacha Isles, FL

Looking for investment property in Matlacha Isles, FL with high ROI ?

Explore a variety of short-term homes & houses in Matlacha Isles, FL. Invest wisely with VRBO & Matlacha Isles, FL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Matlacha Isles, FL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
8642 Whispering Pines Drive MATLACHA ISLES, FL Live the dream on a Southwest Florida island! Nestled on beautiful Pine Island-just 2 mile...	2 beds \| 3 baths \| 1,184 sq.ft.	$499,000	Airbnb cash on cash: -0.4% Traditional cash on cash: 3.33% Airbnb Rental Income: $814 Traditional Rental Income: $2230 Airbnb ROI: -0.4% Traditional ROI: 3.33%
2749 Bruce Street MATLACHA ISLES, FL WATERFRONT FISHERMAN'S DREAM HOME - DEEP CANAL ACCESS, 13,000 LB BOAT LIFT & NEW SALTWATER...	3 beds \| 3 baths \| 1,810 sq.ft.	$725,000	Airbnb cash on cash: -0.34% Traditional cash on cash: 2.99% Airbnb Rental Income: $1204 Traditional Rental Income: $3069 Airbnb ROI: -0.34% Traditional ROI: 2.99%
12304 Boat Shell Drive MATLACHA ISLES, FL Discover a true waterfront escape in unincorporated Matlacha Isles-where quiet island livi...	3 beds \| 3 baths \| 2,340 sq.ft.	$899,900	Airbnb cash on cash: -1.14% Traditional cash on cash: 1.59% Airbnb Rental Income: $1204 Traditional Rental Income: $3099 Airbnb ROI: -1.14% Traditional ROI: 1.59%
2504 Bayshore Drive MATLACHA ISLES, FL Rare MILLION DOLLAR VIEW Bay Front Gulf Access Home - Watch Dolphins from Your Backyard*...	2 beds \| 2 baths \| 1,544 sq.ft.	$650,000	Airbnb cash on cash: -0.82% Traditional cash on cash: 2.96% Airbnb Rental Income: $814 Traditional Rental Income: $2782 Airbnb ROI: -0.82% Traditional ROI: 2.96%
2743 Janet Street MATLACHA ISLES, FL Welcome to 2743 Janet Street, nestled in the sought-after Island Harbors community of Matl...	4 beds \| 3 baths \| 2,235 sq.ft.	$1,100,000	Airbnb cash on cash: -1.25% Traditional cash on cash: 1.32% Airbnb Rental Income: $1147 Traditional Rental Income: $3399 Airbnb ROI: -1.25% Traditional ROI: 1.32%
12234 Boat Shell Dr MATLACHA ISLES, FL This well maintained 2007 built home has everything you're looking for in a Gulf access po...	3 beds \| 2 baths \| 1,960 sq.ft.	$874,900	Airbnb cash on cash: -0.66% Traditional cash on cash: 2.38% Airbnb Rental Income: $1204 Traditional Rental Income: $3291 Airbnb ROI: -0.66% Traditional ROI: 2.38%
12235 Boat Shell Dr MATLACHA ISLES, FL Matlacha Isles Gem - Boater's Paradise - Dual Boat Lifts -No Bridges, Direct Gulf Access! ...	3 beds \| 2 baths \| 1,405 sq.ft.	$775,000	Airbnb cash on cash: -1.26% Traditional cash on cash: 0.89% Airbnb Rental Income: $1204 Traditional Rental Income: $2363 Airbnb ROI: -1.26% Traditional ROI: 0.89%
8500 Redwood Drive MATLACHA ISLES, FL Luxury Island Living!!! This gem includes a 1-year home warranty, $5,000 toward your first...	4 beds \| 3 baths \| 2,632 sq.ft.	$599,000	Airbnb cash on cash: 0.15% Traditional cash on cash: 5.27% Airbnb Rental Income: $1147 Traditional Rental Income: $3628 Airbnb ROI: 0.15% Traditional ROI: 5.27%
2606 Second St MATLACHA ISLES, FL Absolute Rarity Waterfront-Property, in the middle of one of the last places of true "OLD ...	5 beds \| 5 baths \| N/A	$1,175,000	Airbnb cash on cash: -0.76% Traditional cash on cash: 5.61% Airbnb Rental Income: $1147 Traditional Rental Income: $7728 Airbnb ROI: -0.76% Traditional ROI: 5.61%
12230 Matlacha Boulevard MATLACHA ISLES, FL DIRECT SAILBOAT ACCESS - NO LOCKS, NO MISERABLE MILE! Completed in July 2024, this brand-n...	3 beds \| 2 baths \| 1,830 sq.ft.	$606,250	Airbnb cash on cash: -0.53% Traditional cash on cash: 3.58% Airbnb Rental Income: $1204 Traditional Rental Income: $3141 Airbnb ROI: -0.53% Traditional ROI: 3.58%
12262 Boat Shell Drive MATLACHA ISLES, FL HUGE PRICE REDUCTION!!!! Live your best island life in this beautiful fully furnished, TUR...	2 beds \| 2 baths \| 1,244 sq.ft.	$489,000	Airbnb cash on cash: -1.41% Traditional cash on cash: 2.54% Airbnb Rental Income: $814 Traditional Rental Income: $2296 Airbnb ROI: -1.41% Traditional ROI: 2.54%
2562 Bayshore Dr MATLACHA ISLES, FL	2 beds \| 1 baths \| 720 sq.ft.	$339,000	Airbnb cash on cash: -0.27% Traditional cash on cash: 2.75% Airbnb Rental Income: $814 Traditional Rental Income: $1450 Airbnb ROI: -0.27% Traditional ROI: 2.75%
2692 Clyde Street MATLACHA ISLES, FL 2 bedroom/3 bath pool home in Matlacha! This home has a great layout inside and out and th...	2 beds \| 3 baths \| 1,076 sq.ft.	$366,420	Airbnb cash on cash: -0.72% Traditional cash on cash: 5.5% Airbnb Rental Income: $814 Traditional Rental Income: $2630 Airbnb ROI: -0.72% Traditional ROI: 5.5%
2761 Geary Street MATLACHA ISLES, FL **CALL MATLACHA HOME OR USE AS A VACATION RENTAL WITH ABSOLUTELY NO WORRY ABOUT WATER INTR...	2 beds \| 2 baths \| 1,295 sq.ft.	$650,000	Airbnb cash on cash: -1.43% Traditional cash on cash: 1.79% Airbnb Rental Income: $814 Traditional Rental Income: $2441 Airbnb ROI: -1.43% Traditional ROI: 1.79%
4278 Pine Island Road NW MATLACHA ISLES, FL Sitting on the Dock of the Bay - the Best Seat in the House! Welcome to your slice of para...	2 beds \| 1 baths \| 587 sq.ft.	$495,000	Airbnb cash on cash: -0.37% Traditional cash on cash: 2.2% Airbnb Rental Income: $814 Traditional Rental Income: $1681 Airbnb ROI: -0.37% Traditional ROI: 2.2%
12101 Moon Shell Drive MATLACHA ISLES, FL DIRECT GULF ACCESS!!! Located on an oversized cul-de-sac lot with approximately 104 feet o...	2 beds \| 2 baths \| 1,312 sq.ft.	$499,900	Airbnb cash on cash: -1.22% Traditional cash on cash: 2.92% Airbnb Rental Income: $814 Traditional Rental Income: $2424 Airbnb ROI: -1.22% Traditional ROI: 2.92%
5166 Sitka Drive MATLACHA ISLES, FL POOL HOME ON OVER 1/2 AN ACRE CORNER LOT!!! This home was built in 2023 and is in "like ne...	3 beds \| 2 baths \| 1,440 sq.ft.	$422,900	Airbnb cash on cash: 0.63% Traditional cash on cash: 4.8% Airbnb Rental Income: $1204 Traditional Rental Income: $2466 Airbnb ROI: 0.63% Traditional ROI: 4.8%
12196 Matlacha Blvd MATLACHA ISLES, FL INVESTMENT OPPORTUNITY!!!! Matlacha Isles, a direct gulf access community is only minutes ...	3 beds \| 2 baths \| 1,935 sq.ft.	$625,000	Airbnb cash on cash: -1.49% Traditional cash on cash: 2% Airbnb Rental Income: $1204 Traditional Rental Income: $2851 Airbnb ROI: -1.49% Traditional ROI: 2%
2595 Pine Street MATLACHA ISLES, FL You have to see this unique opportunity! WITH TRANSFERABLE FLOOD INSURANCE!! This versatil...	2 beds \| 2 baths \| 824 sq.ft.	$277,000	Airbnb cash on cash: -0.55% Traditional cash on cash: 5.96% Airbnb Rental Income: $814 Traditional Rental Income: $2188 Airbnb ROI: -0.55% Traditional ROI: 5.96%
4760 Pine Island Road NW MATLACHA ISLES, FL Here is your chance to own a slice of waterfront paradise in the historic area of Matlacha...	4 beds \| 4 baths \| 1,284 sq.ft.	$568,000	Airbnb cash on cash: -0.93% Traditional cash on cash: 3.51% Airbnb Rental Income: $1147 Traditional Rental Income: $3121 Airbnb ROI: -0.93% Traditional ROI: 3.51%
12201 Shoreview Drive MATLACHA ISLES, FL Stunning waterfront estate set on 2.24 acres in the heart of Matlacha-truly a boater's par...	5 beds \| 5 baths \| 4,021 sq.ft.	$2,700,000	Airbnb cash on cash: -1.83% Traditional cash on cash: 0.38% Airbnb Rental Income: $1123 Traditional Rental Income: $6302 Airbnb ROI: -1.83% Traditional ROI: 0.38%
2634 Coco Plum Drive MATLACHA ISLES, FL NO FLOODING from any previous hurricanes! OWNER financing available This ELEVATED Gulf...	2 beds \| 2 baths \| 864 sq.ft.	$324,900	Airbnb cash on cash: -0.49% Traditional cash on cash: 4.42% Airbnb Rental Income: $814 Traditional Rental Income: $1992 Airbnb ROI: -0.49% Traditional ROI: 4.42%
4828 FLAMINGO Drive MATLACHA ISLES, FL This is a very beautiful well kept custom built home; not a manufactured home. It has an o...	2 beds \| 2 baths \| 1,094 sq.ft.	$340,000	Airbnb cash on cash: -0.03% Traditional cash on cash: 4.42% Airbnb Rental Income: $814 Traditional Rental Income: $1912 Airbnb ROI: -0.03% Traditional ROI: 4.42%
5099 Flamingo Drive MATLACHA ISLES, FL Water access home that was damaged by the hurricanes. Possible repair or start fresh with ...	1 beds \| 3 baths \| 576 sq.ft.	$99,000	Airbnb cash on cash: -1.32% Traditional cash on cash: 11.86% Airbnb Rental Income: $409 Traditional Rental Income: $1422 Airbnb ROI: -1.32% Traditional ROI: 11.86%
4819 Pine Island Road NW MATLACHA ISLES, FL Wonderful seaside cottage with open water views! On any given day, take in the beautiful s...	2 beds \| 2 baths \| 1,056 sq.ft.	$675,000	Airbnb cash on cash: -0.89% Traditional cash on cash: 1.66% Airbnb Rental Income: $814 Traditional Rental Income: $2098 Airbnb ROI: -0.89% Traditional ROI: 1.66%
2610 Pine Street MATLACHA ISLES, FL Adorable Matlacha cottage on the water nestled just steps away from the heart of the islan...	1 beds \| 1 baths \| 708 sq.ft.	$249,697	Airbnb cash on cash: -1.09% Traditional cash on cash: 5.66% Airbnb Rental Income: $409 Traditional Rental Income: $1744 Airbnb ROI: -1.09% Traditional ROI: 5.66%
2822 Bruce St MATLACHA ISLES, FL Waterfront Island Paradise - Direct Gulf Access, No Bridges! Welcome to your "MOVE IN READ...	2 beds \| 1 baths \| 827 sq.ft.	$419,000	Airbnb cash on cash: -0.59% Traditional cash on cash: 3.03% Airbnb Rental Income: $814 Traditional Rental Income: $1910 Airbnb ROI: -0.59% Traditional ROI: 3.03%
12277 Boat Shell Dr MATLACHA ISLES, FL Direct Gulf-access waterfront home in desirable Matlacha Isles! This recently renovated, c...	3 beds \| 3 baths \| 2,802 sq.ft.	$999,999	Airbnb cash on cash: -0.68% Traditional cash on cash: 2.28% Airbnb Rental Income: $1204 Traditional Rental Income: $3567 Airbnb ROI: -0.68% Traditional ROI: 2.28%
2742 Bruce St MATLACHA ISLES, FL Big NW facing lot for stunning sunsets over the water. Large property with room for trail...	3 beds \| 2 baths \| 1,702 sq.ft.	$474,900	Airbnb cash on cash: -0.5% Traditional cash on cash: 4.18% Airbnb Rental Income: $1204 Traditional Rental Income: $2896 Airbnb ROI: -0.5% Traditional ROI: 4.18%
2631 Bayshore Drive MATLACHA ISLES, FL Welcome to 2631 Bayshore Drive, a classic Matlacha cottage that perfectly blends Old-Flori...	3 beds \| 2 baths \| 1,326 sq.ft.	$485,000	Airbnb cash on cash: -0.98% Traditional cash on cash: 3.37% Airbnb Rental Income: $1204 Traditional Rental Income: $2789 Airbnb ROI: -0.98% Traditional ROI: 3.37%
2831 Janet Street MATLACHA ISLES, FL Janet St- Island Avenue - Matlacha Living at Its Finest. Experience the essence of Florida...	2 beds \| 2 baths \| 1,176 sq.ft.	$599,900	Airbnb cash on cash: -1.3% Traditional cash on cash: 1.96% Airbnb Rental Income: $814 Traditional Rental Income: $2314 Airbnb ROI: -1.3% Traditional ROI: 1.96%
2839 Janet Street MATLACHA ISLES, FL Step into a slice of Old Florida charm with this beautifully updated island cottage nestle...	2 beds \| 2 baths \| 1,001 sq.ft.	$449,900	Airbnb cash on cash: -0.72% Traditional cash on cash: 2.98% Airbnb Rental Income: $814 Traditional Rental Income: $2050 Airbnb ROI: -0.72% Traditional ROI: 2.98%
8721 Nome Court MATLACHA ISLES, FL This 7.07-acre AG-2 zoned property with no deed restrictions has lots of potential and pri...	2 beds \| 1 baths \| 784 sq.ft.	$599,000	Airbnb cash on cash: -0.35% Traditional cash on cash: 1.88% Airbnb Rental Income: $814 Traditional Rental Income: $1734 Airbnb ROI: -0.35% Traditional ROI: 1.88%
4736 Pine Island Road NW MATLACHA ISLES, FL Enjoy the breathtaking sunset views from this amazing Matlacha property. Its's all about l...	2 beds \| 2 baths \| 1,232 sq.ft.	$398,000	Airbnb cash on cash: -0.03% Traditional cash on cash: 5.45% Airbnb Rental Income: $814 Traditional Rental Income: $2532 Airbnb ROI: -0.03% Traditional ROI: 5.45%
8545 Redwood Drive MATLACHA ISLES, FL Motivated sellers-bring all offers! And as an added bonus, the seller's flood insurance po...	2 beds \| 3 baths \| 1,075 sq.ft.	$340,000	Airbnb cash on cash: -0.36% Traditional cash on cash: 4.92% Airbnb Rental Income: $814 Traditional Rental Income: $2176 Airbnb ROI: -0.36% Traditional ROI: 4.92%
4686 Sandpiper Drive MATLACHA ISLES, FL "Two Perfect" 2 BR, 2 Bath, 2 Sheds, 2 Space Carport. Neat, Clean & Cute. Impeccably maint...	2 beds \| 2 baths \| 852 sq.ft.	$189,000	Airbnb cash on cash: 0.79% Traditional cash on cash: 7.25% Airbnb Rental Income: $814 Traditional Rental Income: $1650 Airbnb ROI: 0.79% Traditional ROI: 7.25%
11242 Matlacha Avenue MATLACHA ISLES, FL This charming home in the picturesque town of Matlacha is just footsteps away from the his...	1 beds \| 1 baths \| 480 sq.ft.	$400,000	Airbnb cash on cash: -1.85% Traditional cash on cash: 1.81% Airbnb Rental Income: $409 Traditional Rental Income: $1526 Airbnb ROI: -1.85% Traditional ROI: 1.81%
4754 Woodstock Road MATLACHA ISLES, FL Lovely 3 bedroom 2 bath home on 1.25 acres and zoned AG-2. Home has all new luxury vinyl f...	3 beds \| 2 baths \| 1,420 sq.ft.	$365,000	Airbnb cash on cash: 0.69% Traditional cash on cash: 5.35% Airbnb Rental Income: $1204 Traditional Rental Income: $2409 Airbnb ROI: 0.69% Traditional ROI: 5.35%
11494 May Street MATLACHA ISLES, FL Located in the heart of Matlacha, 11494 May Street is a designated historic cottage that c...	1 beds \| 1 baths \| 535 sq.ft.	$329,900	Airbnb cash on cash: -2.02% Traditional cash on cash: 2.5% Airbnb Rental Income: $409 Traditional Rental Income: $1554 Airbnb ROI: -2.02% Traditional ROI: 2.5%
2480 Bayshore Drive MATLACHA ISLES, FL Motivated Seller needs to sell! Act now to own your own piece of Paradise. Watch the sunri...	3 beds \| 2 baths \| 1,383 sq.ft.	$656,500	Airbnb cash on cash: -0.54% Traditional cash on cash: 2.12% Airbnb Rental Income: $1204 Traditional Rental Income: $2448 Airbnb ROI: -0.54% Traditional ROI: 2.12%

Real Estate investment in Matlacha-isles, FL

There are 70 properties for sale in the city of Matlacha Isles . The median list price in Matlacha Isles is $489,450 and the average price per square foot is $355. In January 2026, the average monthly cash on cash return in Matlacha Isles is 3.00%. The average monthly rental income in Matlacha Isles is $2,363.

Matlacha-isles, FL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 70 investment properties available for sale in Matlacha-isles.

In 2026, the best neighborhood to buy investment property is MATLACHA ISLES.

The ROI for Long-Term is higher than the Short-Term in Matlacha-isles with average rental income of $2,363.

Your search for investment property begins and ends here

Investment Property for Sale in Matlacha Isles, FL

8642 Whispering Pines Drive

MATLACHA ISLES, FL

2 beds | 3 baths | 1,184 sq.ft.

$499,000

Airbnb cash on cash: -0.4%

Traditional cash on cash: 3.33%

Airbnb Rental Income: $814

Traditional Rental Income: $2230

Airbnb ROI: -0.4%

Traditional ROI: 3.33%

2749 Bruce Street

MATLACHA ISLES, FL

3 beds | 3 baths | 1,810 sq.ft.

$725,000

Airbnb cash on cash: -0.34%

Traditional cash on cash: 2.99%

Airbnb Rental Income: $1204

Traditional Rental Income: $3069

Airbnb ROI: -0.34%

Traditional ROI: 2.99%

12304 Boat Shell Drive

MATLACHA ISLES, FL

3 beds | 3 baths | 2,340 sq.ft.

$899,900

Airbnb cash on cash: -1.14%

Traditional cash on cash: 1.59%

Airbnb Rental Income: $1204

Traditional Rental Income: $3099

Airbnb ROI: -1.14%

Traditional ROI: 1.59%

2504 Bayshore Drive

MATLACHA ISLES, FL

2 beds | 2 baths | 1,544 sq.ft.

$650,000

Airbnb cash on cash: -0.82%

Traditional cash on cash: 2.96%

Airbnb Rental Income: $814

Traditional Rental Income: $2782

Airbnb ROI: -0.82%

Traditional ROI: 2.96%

2743 Janet Street

MATLACHA ISLES, FL

4 beds | 3 baths | 2,235 sq.ft.

$1,100,000

Airbnb cash on cash: -1.25%

Traditional cash on cash: 1.32%

Airbnb Rental Income: $1147

Traditional Rental Income: $3399

Airbnb ROI: -1.25%

Traditional ROI: 1.32%

12234 Boat Shell Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,960 sq.ft.

$874,900

Airbnb cash on cash: -0.66%

Traditional cash on cash: 2.38%

Airbnb Rental Income: $1204

Traditional Rental Income: $3291

Airbnb ROI: -0.66%

Traditional ROI: 2.38%

12235 Boat Shell Dr

MATLACHA ISLES, FL

3 beds | 2 baths | 1,405 sq.ft.

$775,000

Airbnb cash on cash: -1.26%

Traditional cash on cash: 0.89%

Airbnb Rental Income: $1204

Traditional Rental Income: $2363

Airbnb ROI: -1.26%

Traditional ROI: 0.89%

8500 Redwood Drive

MATLACHA ISLES, FL

4 beds | 3 baths | 2,632 sq.ft.

$599,000

Airbnb cash on cash: 0.15%

Traditional cash on cash: 5.27%

Airbnb Rental Income: $1147

Traditional Rental Income: $3628

Airbnb ROI: 0.15%