Real Estate Investment Properties for Sale in Cape Girardeau, MO

Looking for investment property in Cape Girardeau, MO with high ROI ?

Explore a variety of short-term homes & houses in Cape Girardeau, MO. Invest wisely with VRBO & Cape Girardeau, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Cape Girardeau, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
715 Terrace Drive Cape Girardeau, MO Birds, bunnies, fireflies, oh my on this private 0.27 acre lot!! While grilling in the woo...	4 beds \| 2 baths \| 2,985 sq.ft.	$284,500	Airbnb cash on cash: 3.52% Traditional cash on cash: 4.66% Airbnb Rental Income: $1912 Traditional Rental Income: $1708 Airbnb ROI: 3.52% Traditional ROI: 4.66%
2325 Brister Hill Drive Cape Girardeau, MO Custom built craftsman house located in the rear of Walden Park that backs up to the Conse...	3 beds \| 3 baths \| 2,022 sq.ft.	$420,000	Airbnb cash on cash: 1.94% Traditional cash on cash: 3.4% Airbnb Rental Income: $2182 Traditional Rental Income: $2202 Airbnb ROI: 1.94% Traditional ROI: 3.4%
3027 Wisteria Drive Cape Girardeau, MO Charming 3 bedroom, 2 bath home with a 2 car garage, situated on a desirable corner lot. T...	3 beds \| 2 baths \| 1,392 sq.ft.	$230,000	Airbnb cash on cash: 5.48% Traditional cash on cash: 6.13% Airbnb Rental Income: $2182 Traditional Rental Income: $1771 Airbnb ROI: 5.48% Traditional ROI: 6.13%
1330 N Sprigg Street #1 Cape Girardeau, MO Spacious home offers 3 bedrooms, 2 baths, eat-in kitchen, huge living room with dining are...	3 beds \| 2 baths \| 1,840 sq.ft.	$149,900	Airbnb cash on cash: 8.46% Traditional cash on cash: 11.51% Airbnb Rental Income: $2182 Traditional Rental Income: $2067 Airbnb ROI: 8.46% Traditional ROI: 11.51%
1535 Rand Street Cape Girardeau, MO Adorable home close to downtown Cape Girardeau, hospital and Southeast Missouri University...	2 beds \| 1 baths \| 720 sq.ft.	$108,000	Airbnb cash on cash: 5.5% Traditional cash on cash: 8.2% Airbnb Rental Income: $1180 Traditional Rental Income: $1078 Airbnb ROI: 5.5% Traditional ROI: 8.2%
890 State Highway Z Cape Girardeau, MO Looking for charm and character in the heart of Gordonville? Look no further! This delight...	3 beds \| 2 baths \| 2,793 sq.ft.	$275,000	Airbnb cash on cash: 4.62% Traditional cash on cash: 6.07% Airbnb Rental Income: $2182 Traditional Rental Income: $2006 Airbnb ROI: 4.62% Traditional ROI: 6.07%
1599 Helmsdale Drive Cape Girardeau, MO Three year old meticulously maintained brick ranch in sought out Dalhousie Subdivision. Op...	3 beds \| 3 baths \| 1,804 sq.ft.	$439,000	Airbnb cash on cash: 2.02% Traditional cash on cash: 3.59% Airbnb Rental Income: $2182 Traditional Rental Income: $2274 Airbnb ROI: 2.02% Traditional ROI: 3.59%
835 Lochinvar Lane Cape Girardeau, MO Step into this well-maintained home offering a comfortable layout and clean, modern feel t...	4 beds \| 3 baths \| 2,252 sq.ft.	$409,900	Airbnb cash on cash: 1.46% Traditional cash on cash: 4.3% Airbnb Rental Income: $1912 Traditional Rental Income: $2498 Airbnb ROI: 1.46% Traditional ROI: 4.3%
2144 Big Bend Road Cape Girardeau, MO Split bedroom ranch on 1.37 acres just before Cape city limits end. Private backyard fenc...	3 beds \| 2 baths \| 1,389 sq.ft.	$289,000	Airbnb cash on cash: 4.11% Traditional cash on cash: 4.55% Airbnb Rental Income: $2182 Traditional Rental Income: $1751 Airbnb ROI: 4.11% Traditional ROI: 4.55%
1736 El Rio Drive Cape Girardeau, MO This beautiful two-story brick-front home greets you with a circle drive and plenty of cur...	4 beds \| 4 baths \| 3,847 sq.ft.	$520,000	Airbnb cash on cash: 1.12% Traditional cash on cash: 6.07% Airbnb Rental Income: $1912 Traditional Rental Income: $3809 Airbnb ROI: 1.12% Traditional ROI: 6.07%
1417 Mary Ann Street Cape Girardeau, MO Extra lot to the right of the home not really build-able. All brick ranch home with 3 bed...	3 beds \| 2 baths \| 1,423 sq.ft.	$175,000	Airbnb cash on cash: 7.74% Traditional cash on cash: 8.44% Airbnb Rental Income: $2182 Traditional Rental Income: $1746 Airbnb ROI: 7.74% Traditional ROI: 8.44%
3818 Eagle Ridge Drive Cape Girardeau, MO Welcome to this charming 4-bedroom, 3-bath home in the desirable Ashland Hills subdivision...	4 beds \| 3 baths \| 2,663 sq.ft.	$315,000	Airbnb cash on cash: 2.8% Traditional cash on cash: 7.06% Airbnb Rental Income: $1912 Traditional Rental Income: $2668 Airbnb ROI: 2.8% Traditional ROI: 7.06%
18 S Benton Street Cape Girardeau, MO This 4-bedroom, 2-bath home has already had some remodeling completed, giving you a solid ...	4 beds \| 2 baths \| 1,325 sq.ft.	$120,000	Airbnb cash on cash: 9.8% Traditional cash on cash: 11.18% Airbnb Rental Income: $1912 Traditional Rental Income: $1565 Airbnb ROI: 9.8% Traditional ROI: 11.18%
1070 Dorothy Street Cape Girardeau, MO Updated Ranch-Style Charmer! Welcome home to this beautifully updated 3-bed, 2-bath ranch...	3 beds \| 2 baths \| 1,580 sq.ft.	$205,900	Airbnb cash on cash: 6.49% Traditional cash on cash: 5.8% Airbnb Rental Income: $2182 Traditional Rental Income: $1494 Airbnb ROI: 6.49% Traditional ROI: 5.8%
2248 Heywood Meadows Cape Girardeau, MO Step inside the welcoming foyer that opens to a spacious living, dining, and kitchen area ...	3 beds \| 2 baths \| 1,515 sq.ft.	$390,000	Airbnb cash on cash: 2.21% Traditional cash on cash: 2.58% Airbnb Rental Income: $2182 Traditional Rental Income: $1767 Airbnb ROI: 2.21% Traditional ROI: 2.58%
290 N Main Street Cape Girardeau, MO Creativity is redefined in this stunning home w/panoramic views where you can absorb all t...	2 beds \| 5 baths \| 2,740 sq.ft.	$895,000	Airbnb cash on cash: -1.23% Traditional cash on cash: 2.21% Airbnb Rental Income: $1180 Traditional Rental Income: $3661 Airbnb ROI: -1.23% Traditional ROI: 2.21%
2001 Donna Street Cape Girardeau, MO Rustic Turnkey Cabin â Perfect for Airbnb or Your Own Mountain Getaway Escape to th...	2 beds \| 1 baths \| 896 sq.ft.	$169,900	Airbnb cash on cash: 2.95% Traditional cash on cash: 5.35% Airbnb Rental Income: $1180 Traditional Rental Income: $1183 Airbnb ROI: 2.95% Traditional ROI: 5.35%
1210 Perryville Road Cape Girardeau, MO You'll love the warmth of the original hardwood flooring and the convenience of a main-lev...	3 beds \| 3 baths \| 1,778 sq.ft.	$220,000	Airbnb cash on cash: 6.07% Traditional cash on cash: 8.54% Airbnb Rental Income: $2182 Traditional Rental Income: $2145 Airbnb ROI: 6.07% Traditional ROI: 8.54%
2640 Walden Boulevard Cape Girardeau, MO Inviting foyer opens to lv, din and kit area w/ 11â ceilings. Kitchen features white woo...	3 beds \| 2 baths \| 1,529 sq.ft.	$378,900	Airbnb cash on cash: 2.07% Traditional cash on cash: 2.87% Airbnb Rental Income: $2182 Traditional Rental Income: $1915 Airbnb ROI: 2.07% Traditional ROI: 2.87%
325 N Main Street Cape Girardeau, MO LUXURY LIVING WITH A MIGHTY VIEW â Exclusive 3 Story Townhome commands a stunning view o...	4 beds \| 5 baths \| 3,578 sq.ft.	$575,000	Airbnb cash on cash: 1.43% Traditional cash on cash: 5.75% Airbnb Rental Income: $1912 Traditional Rental Income: $3723 Airbnb ROI: 1.43% Traditional ROI: 5.75%
239 N Middle Street Cape Girardeau, MO Looking for a promising investment property in a prime location? This apartment complex is...	N/A beds \| N/A baths \| 5,943 sq.ft.	$599,900	Airbnb cash on cash: 0.25% Traditional cash on cash: 0.03% Airbnb Rental Income: $1290 Traditional Rental Income: $758 Airbnb ROI: 0.25% Traditional ROI: 0.03%
5748 State Highway 25 Cape Girardeau, MO Check out this rare gem! Featuring 5 bedrooms on one level, this spacious 1.5 story home ...	5 beds \| 3 baths \| 3,100 sq.ft.	$284,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.72% Airbnb Rental Income: $null Traditional Rental Income: $3065 Airbnb ROI: N/A Traditional ROI: 9.72%
173 Tate Ridge Cape Girardeau, MO This Custom Designed Home is Energy Star Certified through the EPA Energy Star home progra...	4 beds \| 4 baths \| 3,270 sq.ft.	$1,125,000	Airbnb cash on cash: 0.25% Traditional cash on cash: 2.19% Airbnb Rental Income: $1912 Traditional Rental Income: $3443 Airbnb ROI: 0.25% Traditional ROI: 2.19%
292 N Main Street Cape Girardeau, MO Welcome to the River's Edge Townhomes - where luxurious finishes are shared with modern co...	2 beds \| 4 baths \| 2,740 sq.ft.	$895,000	Airbnb cash on cash: -0.38% Traditional cash on cash: 2.2% Airbnb Rental Income: $1180 Traditional Rental Income: $2944 Airbnb ROI: -0.38% Traditional ROI: 2.2%
1401 Bessie Street Cape Girardeau, MO Home features 3 bedrooms/1 bath, newly renovated with new flooring, fresh paint, brand new...	3 beds \| 1 baths \| 1,094 sq.ft.	$159,000	Airbnb cash on cash: 8.75% Traditional cash on cash: 6.6% Airbnb Rental Income: $2182 Traditional Rental Income: $1303 Airbnb ROI: 8.75% Traditional ROI: 6.6%
2153 Esker Trail Cape Girardeau, MO Inviting foyer opens to living, dining and kitchen area w/ 10â ceilings. Kitchen feature...	3 beds \| 2 baths \| 1,571 sq.ft.	$468,900	Airbnb cash on cash: 2.26% Traditional cash on cash: 2.84% Airbnb Rental Income: $2182 Traditional Rental Income: $1883 Airbnb ROI: 2.26% Traditional ROI: 2.84%
2224 Heywood Meadows Cape Girardeau, MO Inviting foyer opens to living, dining and kitchen area w/ 10â ceilings. Kitchen feature...	3 beds \| 2 baths \| 1,457 sq.ft.	$379,900	Airbnb cash on cash: 3.02% Traditional cash on cash: 3.52% Airbnb Rental Income: $2182 Traditional Rental Income: $1810 Airbnb ROI: 3.02% Traditional ROI: 3.52%
309 S Spanish Cape Girardeau, MO If only THIS beautiful home could tell a storyâ¦Imagine all of the stories this stunning,...	3 beds \| 3 baths \| 3,570 sq.ft.	$479,900	Airbnb cash on cash: 2.26% Traditional cash on cash: 3.34% Airbnb Rental Income: $2182 Traditional Rental Income: $2114 Airbnb ROI: 2.26% Traditional ROI: 3.34%
2026 Brink Avenue Cape Girardeau, MO Recent improvements to this 3 bedroom, 2 bath home with a mostly finished basement, includ...	3 beds \| 2 baths \| 1,872 sq.ft.	$170,000	Airbnb cash on cash: 8.03% Traditional cash on cash: 10.91% Airbnb Rental Income: $2182 Traditional Rental Income: $2097 Airbnb ROI: 8.03% Traditional ROI: 10.91%
2161 Esker Trail Cape Girardeau, MO Lot adjoins 6,235 sf common ground lot! Very desirable floor plan with designated entry fo...	3 beds \| 2 baths \| 1,662 sq.ft.	$496,150	Airbnb cash on cash: 2.09% Traditional cash on cash: 2.97% Airbnb Rental Income: $2182 Traditional Rental Income: $2039 Airbnb ROI: 2.09% Traditional ROI: 2.97%
1969 Longview Drive Cape Girardeau, MO ** Looking to start the BER MONTHS off, right?! Well then don't miss out on this beautiful...	4 beds \| 3 baths \| 2,150 sq.ft.	$531,500	Airbnb cash on cash: 0.56% Traditional cash on cash: 2.82% Airbnb Rental Income: $1912 Traditional Rental Income: $2530 Airbnb ROI: 0.56% Traditional ROI: 2.82%
1973 Longview Drive Cape Girardeau, MO * $10,000 in Buyer Incentives with Fall-time savings on select models* Welcome to the ...	4 beds \| 3 baths \| 2,500 sq.ft.	$549,900	Airbnb cash on cash: 0.47% Traditional cash on cash: 2.99% Airbnb Rental Income: $1912 Traditional Rental Income: $2698 Airbnb ROI: 0.47% Traditional ROI: 2.99%
2717 Jewel Drive Cape Girardeau, MO Iconic Design Meets Modern Comfort... If you are a fan of clean lines, open spaces, large...	3 beds \| 2 baths \| 1,929 sq.ft.	$329,900	Airbnb cash on cash: 3.57% Traditional cash on cash: 8.07% Airbnb Rental Income: $2182 Traditional Rental Income: $3024 Airbnb ROI: 3.57% Traditional ROI: 8.07%
1014 N Henderson Avenue Cape Girardeau, MO Welcome to this stunning stone and frame ranch located on a half-acre lot in the heart of ...	4 beds \| 4 baths \| 3,649 sq.ft.	$499,000	Airbnb cash on cash: 1.36% Traditional cash on cash: 6.64% Airbnb Rental Income: $1912 Traditional Rental Income: $3869 Airbnb ROI: 1.36% Traditional ROI: 6.64%
3103 Bloomfield Road Cape Girardeau, MO Looking for the perfect spot to call home? Check out this charming three bedroom, two bath...	3 beds \| 2 baths \| 2,082 sq.ft.	$240,000	Airbnb cash on cash: 5.23% Traditional cash on cash: 8.56% Airbnb Rental Income: $2182 Traditional Rental Income: $2383 Airbnb ROI: 5.23% Traditional ROI: 8.56%
3022 Wisteria Drive Cape Girardeau, MO Welcome to 3022 Wisteria Drive a beautifully remodeled home in Cape Girardeau offering fre...	3 beds \| 2 baths \| 1,827 sq.ft.	$245,000	Airbnb cash on cash: 5.12% Traditional cash on cash: 6.65% Airbnb Rental Income: $2182 Traditional Rental Income: $1983 Airbnb ROI: 5.12% Traditional ROI: 6.65%
3641 Tower Ridge Cape Girardeau, MO Modern elegance meets comfort in this stunning new construction home in the desirable Rock...	3 beds \| 2 baths \| 1,617 sq.ft.	$359,900	Airbnb cash on cash: 2.56% Traditional cash on cash: 3.39% Airbnb Rental Income: $2182 Traditional Rental Income: $1909 Airbnb ROI: 2.56% Traditional ROI: 3.39%
1553 Valley Forge Lane Cape Girardeau, MO Tri-level...EXECUTIVE 3 BEDROOM, 2.5 BATH HOME--UPDATED & MOVE-IN READY! Located on a quie...	3 beds \| 3 baths \| 3,264 sq.ft.	$299,900	Airbnb cash on cash: 3.84% Traditional cash on cash: 5.84% Airbnb Rental Income: $2182 Traditional Rental Income: $2192 Airbnb ROI: 3.84% Traditional ROI: 5.84%
1572 Lexington Avenue Cape Girardeau, MO Located in the Alma Schrader Elementary district, this four-bedroom, three-bath brick ranc...	4 beds \| 3 baths \| 2,264 sq.ft.	$282,900	Airbnb cash on cash: 3.37% Traditional cash on cash: 7.23% Airbnb Rental Income: $1912 Traditional Rental Income: $2433 Airbnb ROI: 3.37% Traditional ROI: 7.23%
1984 Longview Drive Cape Girardeau, MO In-ground SprinklersBacks to TREES!!**Looking at a September Finish!! The Mackenzie P...	4 beds \| 3 baths \| 2,150 sq.ft.	$531,900	Airbnb cash on cash: 0.55% Traditional cash on cash: 2.79% Airbnb Rental Income: $1912 Traditional Rental Income: $2517 Airbnb ROI: 0.55% Traditional ROI: 2.79%

Real Estate investment in Cape-girardeau, MO

There are 103 properties for sale in the city of Cape Girardeau . The median list price in Cape Girardeau is $277,500 and the average price per square foot is $129. In December 2025, the average monthly cash on cash return in Cape Girardeau is 7.00%. The average monthly rental income in Cape Girardeau is $2,145.

Cape-girardeau, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 103 investment properties available for sale in Cape-girardeau.

In 2025, the best neighborhood to buy investment property is Cape Girardeau.

The ROI for Long-Term is higher than the Short-Term in Cape-girardeau with average rental income of $2,145.

Your search for investment property begins and ends here

Investment Property for Sale in Cape Girardeau, MO

715 Terrace Drive

Cape Girardeau, MO

4 beds | 2 baths | 2,985 sq.ft.

$284,500

Airbnb cash on cash: 3.52%

Traditional cash on cash: 4.66%

Airbnb Rental Income: $1912

Traditional Rental Income: $1708

Airbnb ROI: 3.52%

Traditional ROI: 4.66%

2325 Brister Hill Drive

Cape Girardeau, MO

3 beds | 3 baths | 2,022 sq.ft.

$420,000

Airbnb cash on cash: 1.94%

Traditional cash on cash: 3.4%

Airbnb Rental Income: $2182

Traditional Rental Income: $2202

Airbnb ROI: 1.94%

Traditional ROI: 3.4%

3027 Wisteria Drive

Cape Girardeau, MO

3 beds | 2 baths | 1,392 sq.ft.

$230,000

Airbnb cash on cash: 5.48%

Traditional cash on cash: 6.13%

Airbnb Rental Income: $2182

Traditional Rental Income: $1771

Airbnb ROI: 5.48%

Traditional ROI: 6.13%

1330 N Sprigg Street #1

Cape Girardeau, MO

3 beds | 2 baths | 1,840 sq.ft.

$149,900

Airbnb cash on cash: 8.46%

Traditional cash on cash: 11.51%

Airbnb Rental Income: $2182

Traditional Rental Income: $2067

Airbnb ROI: 8.46%

Traditional ROI: 11.51%

1535 Rand Street

Cape Girardeau, MO

2 beds | 1 baths | 720 sq.ft.

$108,000

Airbnb cash on cash: 5.5%

Traditional cash on cash: 8.2%

Airbnb Rental Income: $1180

Traditional Rental Income: $1078

Airbnb ROI: 5.5%

Traditional ROI: 8.2%

890 State Highway Z

Cape Girardeau, MO

3 beds | 2 baths | 2,793 sq.ft.

$275,000

Airbnb cash on cash: 4.62%

Traditional cash on cash: 6.07%

Airbnb Rental Income: $2182

Traditional Rental Income: $2006

Airbnb ROI: 4.62%

Traditional ROI: 6.07%

1599 Helmsdale Drive

Cape Girardeau, MO

3 beds | 3 baths | 1,804 sq.ft.

$439,000

Airbnb cash on cash: 2.02%

Traditional cash on cash: 3.59%

Airbnb Rental Income: $2182

Traditional Rental Income: $2274

Airbnb ROI: 2.02%

Traditional ROI: 3.59%

835 Lochinvar Lane

Cape Girardeau, MO

4 beds | 3 baths | 2,252 sq.ft.

$409,900

Airbnb cash on cash: 1.46%

Traditional cash on cash: 4.3%

Airbnb Rental Income: $1912

Traditional Rental Income: $2498

Airbnb ROI: 1.46%