Real Estate Investment Properties for Sale in Harbor Island, SC

Looking for investment property in Harbor Island, SC with high ROI ?

Explore a variety of short-term homes & houses in Harbor Island, SC. Invest wisely with VRBO & Harbor Island, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Harbor Island, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
86 Harbour Key Drive Harbor Island, SC One of the cutest homes on Harbor Island and one of the original Harbour Key designs. This...	2 beds \| 2 baths \| 1,238 sq.ft.	$609,000	Airbnb cash on cash: 0.98% Traditional cash on cash: 1.3% Airbnb Rental Income: $2859 Traditional Rental Income: $2374 Airbnb ROI: 0.98% Traditional ROI: 1.3%
71 Harbour Key Drive Harbor Island, SC Best Value home on Harbor Island. Harbor Island is scenic, quaint and tropical. With over ...	3 beds \| 3 baths \| 1,800 sq.ft.	$629,000	Airbnb cash on cash: -1.46% Traditional cash on cash: 0.54% Airbnb Rental Income: $1687 Traditional Rental Income: $2391 Airbnb ROI: -1.46% Traditional ROI: 0.54%
2 Cedar Reef Drive #A207 Harbor Island, SC Escape to the beautiful beaches and numerous amenities on Harbor Island! This 2 bedroom, 2...	2 beds \| 3 baths \| 1,080 sq.ft.	$404,900	Airbnb cash on cash: 2.21% Traditional cash on cash: 0.72% Airbnb Rental Income: $2859 Traditional Rental Income: $1627 Airbnb ROI: 2.21% Traditional ROI: 0.72%
1 Cedar Reef Drive #F101 Harbor Island, SC One of the nicest one bedroom Cedar Reef Villas on Harbor Island and is a highly sought af...	1 beds \| 2 baths \| 794 sq.ft.	$339,500	Airbnb cash on cash: -1.27% Traditional cash on cash: 2.14% Airbnb Rental Income: $430 Traditional Rental Income: $1260 Airbnb ROI: -1.27% Traditional ROI: 2.14%
86 Harbor Drive N Harbor Island, SC ACTIVE SHORT-TERM RENTAL OPPORTUNITY - Directly on the sand in the gated beach community o...	3 beds \| 3 baths \| 2,493 sq.ft.	$1,050,000	Airbnb cash on cash: -1% Traditional cash on cash: 0.66% Airbnb Rental Income: $1687 Traditional Rental Income: $2830 Airbnb ROI: -1% Traditional ROI: 0.66%
370 Fripp Point Road Harbor Island, SC Experience the best of Lowcountry riverfront living at 370 Fripp Point Road on St. Helena ...	3 beds \| 3 baths \| 2,790 sq.ft.	$1,175,000	Airbnb cash on cash: -0.79% Traditional cash on cash: 0.38% Airbnb Rental Income: $1687 Traditional Rental Income: $2503 Airbnb ROI: -0.79% Traditional ROI: 0.38%
3 Cedar Reef Drive #E105 Harbor Island, SC Vacation at the beach! This renovated 1 bedroom condo backs up to the community pool with ...	1 beds \| 2 baths \| 794 sq.ft.	$285,000	Airbnb cash on cash: -4.12% Traditional cash on cash: -0.29% Airbnb Rental Income: $430 Traditional Rental Income: $1200 Airbnb ROI: -4.12% Traditional ROI: -0.29%
1 Cedar Reef Drive #F206 Harbor Island, SC Tucked away in the gated community of Harbor Island, experience coastal living at its fine...	2 beds \| 3 baths \| 1,080 sq.ft.	$355,000	Airbnb cash on cash: 1.78% Traditional cash on cash: 0.08% Airbnb Rental Income: $2859 Traditional Rental Income: $1627 Airbnb ROI: 1.78% Traditional ROI: 0.08%
8 Saltwind Drive Harbor Island, SC This treasured Coffin Point Plantation beachfront gem comes fully furnished and sits on a ...	3 beds \| 2 baths \| 2,053 sq.ft.	$1,190,000	Airbnb cash on cash: -1.21% Traditional cash on cash: -0.3% Airbnb Rental Income: $1687 Traditional Rental Income: $2216 Airbnb ROI: -1.21% Traditional ROI: -0.3%
9 Nautical Watch Way Harbor Island, SC Experience the ultimate coastal retreat on Harbor Island! This turnkey, fully furnished ge...	3 beds \| 2 baths \| 1,517 sq.ft.	$679,000	Airbnb cash on cash: -0.75% Traditional cash on cash: 1.3% Airbnb Rental Income: $1687 Traditional Rental Income: $2520 Airbnb ROI: -0.75% Traditional ROI: 1.3%
4 Harbor Drive N #K101 Harbor Island, SC A rare find! This OCEANFRONT first floor 1BR/ 1.5BA villa, a fully furnished end unit enjo...	1 beds \| 2 baths \| 806 sq.ft.	$349,900	Airbnb cash on cash: -1.76% Traditional cash on cash: 1.96% Airbnb Rental Income: $430 Traditional Rental Income: $1390 Airbnb ROI: -1.76% Traditional ROI: 1.96%
170 Harbor Drive N Harbor Island, SC Fabulous Ocean Front Home. One of a kind custom built Beach Front home on the exclusive No...	5 beds \| 3 baths \| 2,516 sq.ft.	$1,450,000	Airbnb cash on cash: -0.6% Traditional cash on cash: -0.3% Airbnb Rental Income: $3122 Traditional Rental Income: $2816 Airbnb ROI: -0.6% Traditional ROI: -0.3%
3 Cedar Reef Drive #E102 Harbor Island, SC Tucked inside the private, gated beach resort of Harbor Island, this beautifully updated 1...	1 beds \| 2 baths \| 806 sq.ft.	$295,000	Airbnb cash on cash: -1.9% Traditional cash on cash: 2.49% Airbnb Rental Income: $430 Traditional Rental Income: $1388 Airbnb ROI: -1.9% Traditional ROI: 2.49%
4 Cedar Reef Drive #B101 Harbor Island, SC Fully furnished 1st floor end 1BR/1.5B. Includes updated window treatments, kitchen applia...	1 beds \| 2 baths \| 806 sq.ft.	$314,900	Airbnb cash on cash: -2.36% Traditional cash on cash: 3.72% Airbnb Rental Income: $430 Traditional Rental Income: $1970 Airbnb ROI: -2.36% Traditional ROI: 3.72%
4 Harbor Drive N #K209 Harbor Island, SC Little Palm Villa is a beautiful Oceanfront fully furnished 2 bedroom, 2.5 bath condo at 4...	2 beds \| 3 baths \| 1,080 sq.ft.	$454,900	Airbnb cash on cash: 3.22% Traditional cash on cash: 2.04% Airbnb Rental Income: $2859 Traditional Rental Income: $1691 Airbnb ROI: 3.22% Traditional ROI: 2.04%
5 Cedar Reef Drive #D206 Harbor Island, SC Experience true coastal living in this beautifully updated and fully furnished 2-bedroom, ...	2 beds \| 3 baths \| 1,069 sq.ft.	$375,000	Airbnb cash on cash: 3.05% Traditional cash on cash: 3.09% Airbnb Rental Income: $2859 Traditional Rental Income: $2208 Airbnb ROI: 3.05% Traditional ROI: 3.09%
3 Cedar Reef Drive #E-108 Harbor Island, SC Experience the epitome of coastal living! This condo is nestled within the serene, gated c...	1 beds \| 2 baths \| 806 sq.ft.	$275,000	Airbnb cash on cash: -1.58% Traditional cash on cash: 6.65% Airbnb Rental Income: $430 Traditional Rental Income: $2303 Airbnb ROI: -1.58% Traditional ROI: 6.65%
6 W Marsh Drive Harbor Island, SC CONSTRUCTION STARTED! Angel by the Sea Beach Cottage! A Great location, water front with b...	3 beds \| 3 baths \| 1,400 sq.ft.	$725,000	Airbnb cash on cash: 0.1% Traditional cash on cash: 1.45% Airbnb Rental Income: $1687 Traditional Rental Income: $2132 Airbnb ROI: 0.1% Traditional ROI: 1.45%
7 Ocean Marsh Court Harbor Island, SC Wonderful opportunity to own this charming home in a very tranquil maritime setting overlo...	3 beds \| 2 baths \| 1,364 sq.ft.	$599,000	Airbnb cash on cash: -0.37% Traditional cash on cash: 1.57% Airbnb Rental Income: $1687 Traditional Rental Income: $2300 Airbnb ROI: -0.37% Traditional ROI: 1.57%
2 Cedar Reef Drive #F101 Harbor Island, SC One of the nicest one bedroom Cedar Reef Villas on Harbor Island and is a highly sought af...	1 beds \| 2 baths \| 806 sq.ft.	$339,500	Airbnb cash on cash: -1.33% Traditional cash on cash: 2.68% Airbnb Rental Income: $430 Traditional Rental Income: $1449 Airbnb ROI: -1.33% Traditional ROI: 2.68%
4 Cedar Reef Drive #B202 Harbor Island, SC Wake up to peaceful marsh views and the relaxed rhythm of Lowcountry living in this beauti...	2 beds \| 3 baths \| 1,080 sq.ft.	$375,000	Airbnb cash on cash: 3.39% Traditional cash on cash: 2.42% Airbnb Rental Income: $2859 Traditional Rental Income: $1855 Airbnb ROI: 3.39% Traditional ROI: 2.42%
71 Harbor Drive Harbor Island, SC Lovely 5 bedroom, 4 bath home with phenomenal ocean view from the front and breathtaking m...	5 beds \| 4 baths \| 2,500 sq.ft.	$1,150,000	Airbnb cash on cash: 0.1% Traditional cash on cash: 0.97% Airbnb Rental Income: $3122 Traditional Rental Income: $3342 Airbnb ROI: 0.1% Traditional ROI: 0.97%
2 Ebb Tide Court Harbor Island, SC OCEAN VIEWS! Welcome to 2 Ebb Tide Court - ''The Crown of the Coast'' gated resort beach c...	4 beds \| 3 baths \| 2,492 sq.ft.	$1,200,000	Airbnb cash on cash: -0.71% Traditional cash on cash: -0.2% Airbnb Rental Income: $2899 Traditional Rental Income: $2799 Airbnb ROI: -0.71% Traditional ROI: -0.2%
4 Harbor Drive N #K207 Harbor Island, SC Wake up to beautiful sunrises from this 2 bedroom oceanfront villa. A short stroll down a ...	2 beds \| 3 baths \| 1,069 sq.ft.	$375,000	Airbnb cash on cash: 1.35% Traditional cash on cash: -0.38% Airbnb Rental Income: $2859 Traditional Rental Income: $1584 Airbnb ROI: 1.35% Traditional ROI: -0.38%
16 Lakeview Lane Harbor Island, SC Ready for island living in a lush and private area on Harbor Island? Ocean Marsh is a golf...	3 beds \| 3 baths \| 1,626 sq.ft.	$748,000	Airbnb cash on cash: -0.18% Traditional cash on cash: 0.97% Airbnb Rental Income: $1687 Traditional Rental Income: $2020 Airbnb ROI: -0.18% Traditional ROI: 0.97%
5 Cedar Reef Drive #D213 Harbor Island, SC This bright and airy ocean front villa will be perfect for your next family vacation. It o...	2 beds \| 3 baths \| 1,069 sq.ft.	$399,000	Airbnb cash on cash: 1.32% Traditional cash on cash: -0.31% Airbnb Rental Income: $2859 Traditional Rental Income: $1584 Airbnb ROI: 1.32% Traditional ROI: -0.31%
2 Harbor Drive #L308 Harbor Island, SC Welcome to this beautifully updated 1 bedroom, 1.5 bath (with walk in shower) on Harbor Is...	1 beds \| 2 baths \| N/A	$259,000	Airbnb cash on cash: -2.11% Traditional cash on cash: 2.29% Airbnb Rental Income: $430 Traditional Rental Income: $1246 Airbnb ROI: -2.11% Traditional ROI: 2.29%
6 N Harbor Drive #M116 Harbor Island, SC Find your place in the sun on beautiful Harbor Island! This 2 BR/2 bath villa offers a sim...	2 beds \| 2 baths \| 1,150 sq.ft.	$379,900	Airbnb cash on cash: 1.05% Traditional cash on cash: -0.86% Airbnb Rental Income: $2859 Traditional Rental Income: $1512 Airbnb ROI: 1.05% Traditional ROI: -0.86%
11 Nautical Watch Way Harbor Island, SC Welcome to ''Rise and Shine'' on beautiful Harbor Island, SC. This 4 BR 3 BA home has unob...	4 beds \| 3 baths \| 2,022 sq.ft.	$849,000	Airbnb cash on cash: 1.1% Traditional cash on cash: 1.39% Airbnb Rental Income: $2899 Traditional Rental Income: $2458 Airbnb ROI: 1.1% Traditional ROI: 1.39%
50 Sea Pines Drive Harbor Island, SC Experience a private Lowcountry retreat at 50 Sea Pines Drive, set beneath a canopy of mat...	3 beds \| 2 baths \| 1,344 sq.ft.	$395,000	Airbnb cash on cash: 0.87% Traditional cash on cash: 2.56% Airbnb Rental Income: $1687 Traditional Rental Income: $1845 Airbnb ROI: 0.87% Traditional ROI: 2.56%
2 Harbor Drive #L205 Harbor Island, SC Breathe in the salt air and slow down to the rhythm of the tides. This fully furnished, oc...	1 beds \| 2 baths \| 714 sq.ft.	$255,000	Airbnb cash on cash: -6.4% Traditional cash on cash: -1.39% Airbnb Rental Income: $430 Traditional Rental Income: $1374 Airbnb ROI: -6.4% Traditional ROI: -1.39%
1 Cedar Reef Drive #F204 Harbor Island, SC BEST DEAL on Harbor Island. This two-bedroom villa is listed for less than the price of a ...	2 beds \| 3 baths \| 1,069 sq.ft.	$289,000	Airbnb cash on cash: 5.63% Traditional cash on cash: 3.59% Airbnb Rental Income: $2859 Traditional Rental Income: $1638 Airbnb ROI: 5.63% Traditional ROI: 3.59%
151 Tom And Mike Road Harbor Island, SC Luxury Live Auction! Bidding to start from $700,000.00! Enjoy your privacy with this tidal...	3 beds \| 3 baths \| 3,504 sq.ft.	$700,000	Airbnb cash on cash: 0.15% Traditional cash on cash: 1.09% Airbnb Rental Income: $1687 Traditional Rental Income: $1827 Airbnb ROI: 0.15% Traditional ROI: 1.09%

Real Estate investment in Harbor-island, SC

There are 49 properties for sale in the city of Harbor Island . The median list price in Harbor Island is $774,600 and the average price per square foot is $499. In June 2026, the average monthly cash on cash return in Harbor Island is 1.00%. The average monthly rental income in Harbor Island is $1,852.

Harbor-island, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 49 investment properties available for sale in Harbor-island.

In 2026, the best neighborhood to buy investment property is Harbor Island.

The ROI for Short-Term is higher than the Long-Term in Harbor-island with average rental income of $1,687.

Your search for investment property begins and ends here

Investment Property for Sale in Harbor Island, SC

86 Harbour Key Drive

Harbor Island, SC

2 beds | 2 baths | 1,238 sq.ft.

$609,000

Airbnb cash on cash: 0.98%

Traditional cash on cash: 1.3%

Airbnb Rental Income: $2859

Traditional Rental Income: $2374

Airbnb ROI: 0.98%

Traditional ROI: 1.3%

71 Harbour Key Drive

Harbor Island, SC

3 beds | 3 baths | 1,800 sq.ft.

$629,000

Airbnb cash on cash: -1.46%

Traditional cash on cash: 0.54%

Airbnb Rental Income: $1687

Traditional Rental Income: $2391

Airbnb ROI: -1.46%

Traditional ROI: 0.54%

2 Cedar Reef Drive #A207

Harbor Island, SC

2 beds | 3 baths | 1,080 sq.ft.

$404,900

Airbnb cash on cash: 2.21%

Traditional cash on cash: 0.72%

Airbnb Rental Income: $2859

Traditional Rental Income: $1627

Airbnb ROI: 2.21%

Traditional ROI: 0.72%

1 Cedar Reef Drive #F101

Harbor Island, SC

1 beds | 2 baths | 794 sq.ft.

$339,500

Airbnb cash on cash: -1.27%

Traditional cash on cash: 2.14%

Airbnb Rental Income: $430

Traditional Rental Income: $1260

Airbnb ROI: -1.27%

Traditional ROI: 2.14%

86 Harbor Drive N

Harbor Island, SC

3 beds | 3 baths | 2,493 sq.ft.

$1,050,000

Airbnb cash on cash: -1%

Traditional cash on cash: 0.66%

Airbnb Rental Income: $1687

Traditional Rental Income: $2830

Airbnb ROI: -1%

Traditional ROI: 0.66%

370 Fripp Point Road

Harbor Island, SC

3 beds | 3 baths | 2,790 sq.ft.

$1,175,000

Airbnb cash on cash: -0.79%

Traditional cash on cash: 0.38%

Airbnb Rental Income: $1687

Traditional Rental Income: $2503

Airbnb ROI: -0.79%

Traditional ROI: 0.38%

3 Cedar Reef Drive #E105

Harbor Island, SC

1 beds | 2 baths | 794 sq.ft.

$285,000

Airbnb cash on cash: -4.12%

Traditional cash on cash: -0.29%

Airbnb Rental Income: $430

Traditional Rental Income: $1200

Airbnb ROI: -4.12%

Traditional ROI: -0.29%

1 Cedar Reef Drive #F206

Harbor Island, SC

2 beds | 3 baths | 1,080 sq.ft.

$355,000

Airbnb cash on cash: 1.78%

Traditional cash on cash: 0.08%

Airbnb Rental Income: $2859

Traditional Rental Income: $1627

Airbnb ROI: 1.78%