Airbnb Properties for Sale in Panacea, FL

Looking for a vacation rental investment in Panacea, FL with high ROI ?

Explore a range of newly added short-term rental homes in Panacea, FL. Make a smart investment with newly available Airbnb properties and find the ideal high-ROI property for sale.

Airbnb For Sale in Panacea, FL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
38 Sunrise Lane Panacea, FL This beautiful beach house is being sold furnished, ready for you to bring your suitcases ...	3 beds \| 3 baths \| 1,508 sq.ft.	$699,900	Airbnb cash on cash: 5.53% Traditional cash on cash: 1.87% Airbnb Rental Income: $5991 Traditional Rental Income: $2419 Airbnb ROI: 5.53% Traditional ROI: 1.87%
40 POMPANO Drive Panacea, FL Welcome to your slice of Old Florida paradise in the heart of Panacea! This charming canal...	3 beds \| 2 baths \| 1,560 sq.ft.	$490,000	Airbnb cash on cash: 8.34% Traditional cash on cash: 2.29% Airbnb Rental Income: $5991 Traditional Rental Income: $2033 Airbnb ROI: 8.34% Traditional ROI: 2.29%
2519 Surf Road Panacea, FL Looking for a peaceful bay house with the deepest water and views that are protected? This...	3 beds \| 2 baths \| 1,952 sq.ft.	$689,900	Airbnb cash on cash: 5.73% Traditional cash on cash: 2.22% Airbnb Rental Income: $5991 Traditional Rental Income: $2548 Airbnb ROI: 5.73% Traditional ROI: 2.22%
1448 CYPRESS STREET Panacea, FL 1448 Cypress Street, Alligator Point, FL 32346 Offered at $625,000 3 Bedrooms \| 3 Bathro...	3 beds \| 4 baths \| 1,412 sq.ft.	$625,000	Airbnb cash on cash: 6.46% Traditional cash on cash: 2.51% Airbnb Rental Income: $5991 Traditional Rental Income: $2505 Airbnb ROI: 6.46% Traditional ROI: 2.51%
39 Aucilla Street Panacea, FL Incredible opportunity to own this "Must See" Property located on Florida's Forgotten Coas...	3 beds \| 2 baths \| 2,093 sq.ft.	$695,000	Airbnb cash on cash: 5.82% Traditional cash on cash: 2.05% Airbnb Rental Income: $5991 Traditional Rental Income: $2356 Airbnb ROI: 5.82% Traditional ROI: 2.05%
13 Aucilla Street Panacea, FL 2019 custom-built home with over 2,100 sq. ft. of conditioned space. This house sits upon ...	3 beds \| 3 baths \| 2,171 sq.ft.	$425,000	Airbnb cash on cash: 9.89% Traditional cash on cash: 4.42% Airbnb Rental Income: $5991 Traditional Rental Income: $2625 Airbnb ROI: 9.89% Traditional ROI: 4.42%
367 Mashes Sands Road Panacea, FL Find your way home to this Ochlockonee Bay waterfront home nestled high amongst the live o...	3 beds \| 3 baths \| 2,028 sq.ft.	$529,900	Airbnb cash on cash: 8.05% Traditional cash on cash: 5.28% Airbnb Rental Income: $5991 Traditional Rental Income: $3433 Airbnb ROI: 8.05% Traditional ROI: 5.28%
25 Mashes Sands Road unit: I #I Panacea, FL Welcome to your dream waterfront home! Nestled at Georges Lighthouse, this exquisite townh...	3 beds \| 3 baths \| 1,496 sq.ft.	$439,900	Airbnb cash on cash: 8.98% Traditional cash on cash: 2.56% Airbnb Rental Income: $5991 Traditional Rental Income: $2163 Airbnb ROI: 8.98% Traditional ROI: 2.56%
1667 Alligator Drive Panacea, FL Blending modern updates with timeless coastal charm, this home is truly move-in ready. A r...	3 beds \| 4 baths \| 3,146 sq.ft.	$1,945,000	Airbnb cash on cash: 1.19% Traditional cash on cash: 1.16% Airbnb Rental Income: $5991 Traditional Rental Income: $4740 Airbnb ROI: 1.19% Traditional ROI: 1.16%

Vacation Rentals in Panacea

There are 9 vacation rental properties available for sale in the city of Panacea . The median list price of Airbnb properties available for sale in Panacea is $454,500 and the average price per square foot is $264. The cash on cash return on vacation rentals in Panacea is 3.00%. The average monthly short term rental income in Panacea is $2,270.

Panacea, FL Short Term Rentals FAQs for Buyers, Sellers and Investors

There are 9 Airbnb properties available for sale in Panacea.

In 2025, the best neighborhood to buy short term rental property is Panacea.

In September 2025, the average Airbnb occupancy rate in Panacea is 51%.

Airbnb data on vacation rentals in Panacea, FL is available at Mashvisor. You can access data such as listings, real-time pricing trends, Panacea, FL market insights, guest information and booking details, seasonality trends and historical Panacea, FL Airbnb performance data.

Your search for investment property begins and ends here

Airbnb For Sale in Panacea, FL

38 Sunrise Lane

Panacea, FL

3 beds | 3 baths | 1,508 sq.ft.

$699,900

Airbnb cash on cash: 5.53%

Traditional cash on cash: 1.87%

Airbnb Rental Income: $5991

Traditional Rental Income: $2419

Airbnb ROI: 5.53%

Traditional ROI: 1.87%

40 POMPANO Drive

Panacea, FL

3 beds | 2 baths | 1,560 sq.ft.

$490,000

Airbnb cash on cash: 8.34%

Traditional cash on cash: 2.29%

Airbnb Rental Income: $5991

Traditional Rental Income: $2033

Airbnb ROI: 8.34%

Traditional ROI: 2.29%

2519 Surf Road

Panacea, FL

3 beds | 2 baths | 1,952 sq.ft.

$689,900

Airbnb cash on cash: 5.73%

Traditional cash on cash: 2.22%

Airbnb Rental Income: $5991

Traditional Rental Income: $2548

Airbnb ROI: 5.73%

Traditional ROI: 2.22%

1448 CYPRESS STREET

Panacea, FL

3 beds | 4 baths | 1,412 sq.ft.

$625,000

Airbnb cash on cash: 6.46%

Traditional cash on cash: 2.51%

Airbnb Rental Income: $5991

Traditional Rental Income: $2505

Airbnb ROI: 6.46%

Traditional ROI: 2.51%

39 Aucilla Street

Panacea, FL

3 beds | 2 baths | 2,093 sq.ft.

$695,000

Airbnb cash on cash: 5.82%

Traditional cash on cash: 2.05%

Airbnb Rental Income: $5991

Traditional Rental Income: $2356

Airbnb ROI: 5.82%

Traditional ROI: 2.05%

13 Aucilla Street

Panacea, FL

3 beds | 3 baths | 2,171 sq.ft.

$425,000

Airbnb cash on cash: 9.89%

Traditional cash on cash: 4.42%

Airbnb Rental Income: $5991

Traditional Rental Income: $2625

Airbnb ROI: 9.89%

Traditional ROI: 4.42%

367 Mashes Sands Road

Panacea, FL

3 beds | 3 baths | 2,028 sq.ft.

$529,900

Airbnb cash on cash: 8.05%

Traditional cash on cash: 5.28%

Airbnb Rental Income: $5991

Traditional Rental Income: $3433

Airbnb ROI: 8.05%

Traditional ROI: 5.28%

25 Mashes Sands Road unit: I #I

Panacea, FL

3 beds | 3 baths | 1,496 sq.ft.

$439,900

Airbnb cash on cash: 8.98%

Traditional cash on cash: 2.56%

Airbnb Rental Income: $5991

Traditional Rental Income: $2163

Airbnb ROI: 8.98%