Real Estate Investment Properties for Sale in Tuscumbia, AL

Looking for investment property in Tuscumbia, AL with high ROI ?

Explore a variety of short-term homes & houses in Tuscumbia, AL. Invest wisely with VRBO & Tuscumbia, AL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Tuscumbia, AL

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
162 Valley Grove St Tuscumbia, AL Welcome to your dream home in the heart of Tuscumbia, Alabama! Built in 2020, this exquisi...	3 beds \| 3 baths \| 2,150 sq.ft.	$469,490	Airbnb cash on cash: 1.85% Traditional cash on cash: 4.19% Airbnb Rental Income: $1954 Traditional Rental Income: $2464 Airbnb ROI: 1.85% Traditional ROI: 4.19%
1455 Jackson Hwy Tuscumbia, AL Welcome home to this open concept 3 Bedroom 2 Bath rancher with lots of room to roam!! Loc...	3 beds \| 2 baths \| 2,200 sq.ft.	$240,000	Airbnb cash on cash: 4.61% Traditional cash on cash: 8.65% Airbnb Rental Income: $1954 Traditional Rental Income: $2355 Airbnb ROI: 4.61% Traditional ROI: 8.65%
165 Reid Ave Tuscumbia, AL Discover this beautifully remodeled 3-bedroom, 2-bath home, perfectly situated on a spacio...	3 beds \| 2 baths \| 1,660 sq.ft.	$242,000	Airbnb cash on cash: 4.74% Traditional cash on cash: 4.97% Airbnb Rental Income: $1954 Traditional Rental Income: $1491 Airbnb ROI: 4.74% Traditional ROI: 4.97%
208 Maclin Cir Tuscumbia, AL Custom built 3 bedroom, 2 full bath Florida style home with pool in convenient Tuscumbia n...	3 beds \| 2 baths \| 2,950 sq.ft.	$529,900	Airbnb cash on cash: 1.43% Traditional cash on cash: 2.91% Airbnb Rental Income: $1954 Traditional Rental Income: $2169 Airbnb ROI: 1.43% Traditional ROI: 2.91%
105 Fieldwood Dr Tuscumbia, AL This beautiful 3 bedroom 2 bath home in Tuscumbia city limits. House sits on two lots on a...	4 beds \| 2 baths \| 2,193 sq.ft.	$499,900	Airbnb cash on cash: 1.5% Traditional cash on cash: 2.45% Airbnb Rental Income: $1954 Traditional Rental Income: $1881 Airbnb ROI: 1.5% Traditional ROI: 2.45%
202 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$465,000	Airbnb cash on cash: 1.63% Traditional cash on cash: 4.39% Airbnb Rental Income: $1954 Traditional Rental Income: $2638 Airbnb ROI: 1.63% Traditional ROI: 4.39%
203 Fame Ave Tuscumbia, AL Welcome to your dream home! This stunning 3-bedroom, 2.5-bath residence boasts 1,822 sq ft...	3 beds \| 3 baths \| 1,822 sq.ft.	$374,000	Airbnb cash on cash: 2.36% Traditional cash on cash: 4.96% Airbnb Rental Income: $1954 Traditional Rental Income: $2353 Airbnb ROI: 2.36% Traditional ROI: 4.96%
101 N Cave St Tuscumbia, AL Old town charm meets classical elegance in this historical home near downtown Tuscumbia. ...	5 beds \| 3 baths \| 3,459 sq.ft.	$345,000	Airbnb cash on cash: 0.84% Traditional cash on cash: 9.43% Airbnb Rental Income: $1240 Traditional Rental Income: $3628 Airbnb ROI: 0.84% Traditional ROI: 9.43%
608 Eastman Ave Tuscumbia, AL Your going to fall in love with this spacious three bedroom, three bath home with large bo...	3 beds \| 3 baths \| 2,300 sq.ft.	$349,900	Airbnb cash on cash: 2.69% Traditional cash on cash: 6.43% Airbnb Rental Income: $1954 Traditional Rental Income: $2669 Airbnb ROI: 2.69% Traditional ROI: 6.43%
800 E 5th St Tuscumbia, AL This beautiful ranch style, main level, home is full of old world charm! Just a short dis...	4 beds \| 3 baths \| 2,903 sq.ft.	$329,900	Airbnb cash on cash: 3.11% Traditional cash on cash: 8.54% Airbnb Rental Income: $1954 Traditional Rental Income: $3124 Airbnb ROI: 3.11% Traditional ROI: 8.54%
409 N Jefferson St Tuscumbia, AL Great investment opportunity! Duplex in Tuscumbia, corner lot (409 Jefferson & 401 First S...	N/A beds \| N/A baths \| N/A	$156,900	Airbnb cash on cash: 7.37% Traditional cash on cash: 5.4% Airbnb Rental Income: $1954 Traditional Rental Income: $1144 Airbnb ROI: 7.37% Traditional ROI: 5.4%
302 Fame Ave Tuscumbia, AL This newly constructed 3-bedroom, 2.5-bathroom modern tudor home is designed with elegant ...	3 beds \| 3 baths \| 2,320 sq.ft.	$519,000	Airbnb cash on cash: 1.32% Traditional cash on cash: 3.75% Airbnb Rental Income: $1954 Traditional Rental Income: $2620 Airbnb ROI: 1.32% Traditional ROI: 3.75%
304 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$467,900	Airbnb cash on cash: 1.61% Traditional cash on cash: 4.37% Airbnb Rental Income: $1954 Traditional Rental Income: $2647 Airbnb ROI: 1.61% Traditional ROI: 4.37%
1513 Joe Wheeler Dr Tuscumbia, AL Don't wait too long to see this charming house that has been updated inside as well as out...	2 beds \| 2 baths \| 1,600 sq.ft.	$159,900	Airbnb cash on cash: 4.39% Traditional cash on cash: 11.62% Airbnb Rental Income: $1380 Traditional Rental Income: $2065 Airbnb ROI: 4.39% Traditional ROI: 11.62%
2762 Old Hwy 20 Tuscumbia, AL Cornelius Landing! Muscle Shoals school district!! Don't miss this custom built 4 bedroom ...	4 beds \| 3 baths \| 2,280 sq.ft.	$449,900	Airbnb cash on cash: 1.85% Traditional cash on cash: 4.51% Airbnb Rental Income: $1954 Traditional Rental Income: $2563 Airbnb ROI: 1.85% Traditional ROI: 4.51%
1309 English Ln Tuscumbia, AL There is nothing missing in this nicely, updated brick house. Seller installed a sound pro...	3 beds \| 2 baths \| 1,479 sq.ft.	$219,999	Airbnb cash on cash: 5.11% Traditional cash on cash: 7.54% Airbnb Rental Income: $1954 Traditional Rental Income: $1945 Airbnb ROI: 5.11% Traditional ROI: 7.54%
1540 Woodmont Dr Tuscumbia, AL Cute & cozy home totally rebuilt with approximately 16 acres! This home was taken down to ...	3 beds \| 2 baths \| 1,132 sq.ft.	$239,900	Airbnb cash on cash: 4.71% Traditional cash on cash: 5.91% Airbnb Rental Income: $1954 Traditional Rental Income: $1713 Airbnb ROI: 4.71% Traditional ROI: 5.91%
121 Fame Ave Tuscumbia, AL Brand New Home Under Construction- Customize it Your Way! This stunning 3-bedroom 3-bathro...	3 beds \| 3 baths \| 2,282 sq.ft.	$479,900	Airbnb cash on cash: 1.54% Traditional cash on cash: 3.98% Airbnb Rental Income: $1954 Traditional Rental Income: $2534 Airbnb ROI: 1.54% Traditional ROI: 3.98%
306 Fame Ave Tuscumbia, AL New Construction Home in Sound Crossings- Muscle Shoals School District! Don?t miss this u...	5 beds \| 3 baths \| 2,889 sq.ft.	$652,000	Airbnb cash on cash: -0.21% Traditional cash on cash: 3.04% Airbnb Rental Income: $1240 Traditional Rental Income: $2823 Airbnb ROI: -0.21% Traditional ROI: 3.04%
1004 Hemlock St Tuscumbia, AL Three bedroom/2 bath home in the Belview Heights Subdivision in Tuscumbia. This split-lev...	3 beds \| 2 baths \| 2,347 sq.ft.	$239,000	Airbnb cash on cash: 4.63% Traditional cash on cash: 8.88% Airbnb Rental Income: $1954 Traditional Rental Income: $2398 Airbnb ROI: 4.63% Traditional ROI: 8.88%
205 Fame Ave Tuscumbia, AL Come be a part of Muscle Shoals' newest planned community, Sound Crossing. This home is fu...	3 beds \| 3 baths \| 2,320 sq.ft.	$475,600	Airbnb cash on cash: 1.62% Traditional cash on cash: 4.09% Airbnb Rental Income: $1954 Traditional Rental Income: $2539 Airbnb ROI: 1.62% Traditional ROI: 4.09%
82 Rockwood Dr Tuscumbia, AL Welcome to your dream home! This beautifully crafted 2,550 square foot residence, built in...	4 beds \| 4 baths \| 2,550 sq.ft.	$439,900	Airbnb cash on cash: 1.97% Traditional cash on cash: 5.36% Airbnb Rental Income: $1954 Traditional Rental Income: $2835 Airbnb ROI: 1.97% Traditional ROI: 5.36%
311 E 6th Street Tuscumbia, AL Step into one of Tuscumbiaâs most iconic homes â the âHeflin House.â This nearly 4...	4 beds \| 3 baths \| 3,867 sq.ft.	$345,000	Airbnb cash on cash: 2.74% Traditional cash on cash: 8.11% Airbnb Rental Income: $1954 Traditional Rental Income: $3182 Airbnb ROI: 2.74% Traditional ROI: 8.11%
889 Blake Dr Tuscumbia, AL This is truly a rare gem offering 7,200 square feet of elegant and functional living space...	5 beds \| 6 baths \| 7,202 sq.ft.	$895,000	Airbnb cash on cash: -0.3% Traditional cash on cash: 6.35% Airbnb Rental Income: $1240 Traditional Rental Income: $6385 Airbnb ROI: -0.3% Traditional ROI: 6.35%
425 Cedar Hill Ln Tuscumbia, AL Listing agent is related to seller. Contingent upon Medicaid approval. Home to be sold "AS...	3 beds \| 2 baths \| 2,066 sq.ft.	$325,000	Airbnb cash on cash: 3.14% Traditional cash on cash: 5.86% Airbnb Rental Income: $1954 Traditional Rental Income: $2271 Airbnb ROI: 3.14% Traditional ROI: 5.86%
1100 Raintree Dr Tuscumbia, AL You will love this beautiful home sitting on almost one acre in rural Tuscumbia!Â This 3,...	4 beds \| 3 baths \| 3,876 sq.ft.	$430,000	Airbnb cash on cash: 2.09% Traditional cash on cash: 5.36% Airbnb Rental Income: $1954 Traditional Rental Income: $2758 Airbnb ROI: 2.09% Traditional ROI: 5.36%
905 Old Lee Hwy Tuscumbia, AL Welcome to this fully remodeled 3-bedroom, 2-bathroom home is a must-see for anyone seekin...	3 beds \| 2 baths \| 1,010 sq.ft.	$169,900	Airbnb cash on cash: 6.94% Traditional cash on cash: 8.4% Airbnb Rental Income: $1954 Traditional Rental Income: $1675 Airbnb ROI: 6.94% Traditional ROI: 8.4%
804 E 7th St Tuscumbia, AL No stone unturned on this beautifully done remodel. Come see this charming 2 bedroom/1 bat...	2 beds \| 1 baths \| 1,088 sq.ft.	$169,000	Airbnb cash on cash: 4.1% Traditional cash on cash: 6.45% Airbnb Rental Income: $1380 Traditional Rental Income: $1339 Airbnb ROI: 4.1% Traditional ROI: 6.45%
311 E 4th Tuscumbia, AL Step into a beautifully preserved piece of history in the heart of Downtown Tuscumbia. Thi...	2 beds \| 2 baths \| 1,871 sq.ft.	$224,900	Airbnb cash on cash: 2.78% Traditional cash on cash: 8.41% Airbnb Rental Income: $1380 Traditional Rental Income: $2158 Airbnb ROI: 2.78% Traditional ROI: 8.41%
103 White City Dr Tuscumbia, AL Charming Home on a Large Corner Lot in a Sought-After Tuscumbia Neighborhood! This 3-bedro...	3 beds \| 2 baths \| 2,015 sq.ft.	$244,900	Airbnb cash on cash: 4.5% Traditional cash on cash: 8.45% Airbnb Rental Income: $1954 Traditional Rental Income: $2354 Airbnb ROI: 4.5% Traditional ROI: 8.45%
1705 Keller Quarry Rd Tuscumbia, AL Charming 3 bedrooms, 2 bath home on 1 acre corner lot near Pickwick Lake. Freshly painted...	3 beds \| 2 baths \| 1,632 sq.ft.	$269,900	Airbnb cash on cash: 3.88% Traditional cash on cash: 6.02% Airbnb Rental Income: $1954 Traditional Rental Income: $1984 Airbnb ROI: 3.88% Traditional ROI: 6.02%
1402 Vista Cir Tuscumbia, AL Here is your opportunity to be a part of this quiet neighborhood in beautiful Tuscumbia. T...	3 beds \| 2 baths \| 1,288 sq.ft.	$174,900	Airbnb cash on cash: 6.67% Traditional cash on cash: 8.19% Airbnb Rental Income: $1954 Traditional Rental Income: $1693 Airbnb ROI: 6.67% Traditional ROI: 8.19%
710 N High St Tuscumbia, AL Check out this well maintained home in the heart of Tuscumbia. This spacious 3 bed, 1.5 ba...	3 beds \| 2 baths \| 1,300 sq.ft.	$184,900	Airbnb cash on cash: 6.24% Traditional cash on cash: 8.07% Airbnb Rental Income: $1954 Traditional Rental Income: $1761 Airbnb ROI: 6.24% Traditional ROI: 8.07%
110 Emerald Dr Tuscumbia, AL Charming Updated Home on a Quiet Tuscumbia Street. Donât miss this beautifully updated h...	3 beds \| 2 baths \| 1,513 sq.ft.	$194,900	Airbnb cash on cash: 5.71% Traditional cash on cash: 8.75% Airbnb Rental Income: $1954 Traditional Rental Income: $2003 Airbnb ROI: 5.71% Traditional ROI: 8.75%

Real Estate investment in Tuscumbia, AL

There are 57 properties for sale in the city of Tuscumbia . The median list price in Tuscumbia is $249,900 and the average price per square foot is $118. In September 2025, the average monthly cash on cash return in Tuscumbia is 8.00%. The average monthly rental income in Tuscumbia is $2,351.

Tuscumbia, AL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 57 investment properties available for sale in Tuscumbia.

In 2025, the best neighborhood to buy investment property is Tuscumbia.

The ROI for Long-Term is higher than the Short-Term in Tuscumbia with average rental income of $2,351.

Your search for investment property begins and ends here

Investment Property for Sale in Tuscumbia, AL

162 Valley Grove St

Tuscumbia, AL

3 beds | 3 baths | 2,150 sq.ft.

$469,490

Airbnb cash on cash: 1.85%

Traditional cash on cash: 4.19%

Airbnb Rental Income: $1954

Traditional Rental Income: $2464

Airbnb ROI: 1.85%

Traditional ROI: 4.19%

1455 Jackson Hwy

Tuscumbia, AL

3 beds | 2 baths | 2,200 sq.ft.

$240,000

Airbnb cash on cash: 4.61%

Traditional cash on cash: 8.65%

Airbnb Rental Income: $1954

Traditional Rental Income: $2355

Airbnb ROI: 4.61%

Traditional ROI: 8.65%

165 Reid Ave

Tuscumbia, AL

3 beds | 2 baths | 1,660 sq.ft.

$242,000

Airbnb cash on cash: 4.74%

Traditional cash on cash: 4.97%

Airbnb Rental Income: $1954

Traditional Rental Income: $1491

Airbnb ROI: 4.74%

Traditional ROI: 4.97%

208 Maclin Cir

Tuscumbia, AL

3 beds | 2 baths | 2,950 sq.ft.

$529,900

Airbnb cash on cash: 1.43%

Traditional cash on cash: 2.91%

Airbnb Rental Income: $1954

Traditional Rental Income: $2169

Airbnb ROI: 1.43%

Traditional ROI: 2.91%

105 Fieldwood Dr

Tuscumbia, AL

4 beds | 2 baths | 2,193 sq.ft.

$499,900

Airbnb cash on cash: 1.5%

Traditional cash on cash: 2.45%

Airbnb Rental Income: $1954

Traditional Rental Income: $1881

Airbnb ROI: 1.5%

Traditional ROI: 2.45%

202 Fame Ave

Tuscumbia, AL

3 beds | 3 baths | 2,282 sq.ft.

$465,000

Airbnb cash on cash: 1.63%

Traditional cash on cash: 4.39%

Airbnb Rental Income: $1954

Traditional Rental Income: $2638

Airbnb ROI: 1.63%

Traditional ROI: 4.39%

203 Fame Ave

Tuscumbia, AL

3 beds | 3 baths | 1,822 sq.ft.

$374,000

Airbnb cash on cash: 2.36%

Traditional cash on cash: 4.96%

Airbnb Rental Income: $1954

Traditional Rental Income: $2353

Airbnb ROI: 2.36%

Traditional ROI: 4.96%

101 N Cave St

Tuscumbia, AL

5 beds | 3 baths | 3,459 sq.ft.

$345,000

Airbnb cash on cash: 0.84%

Traditional cash on cash: 9.43%

Airbnb Rental Income: $1240

Traditional Rental Income: $3628

Airbnb ROI: 0.84%