Real Estate Investment Properties for Sale in Tuscumbia, AL

Looking for investment property in Tuscumbia, AL with high ROI ?

Explore a variety of short-term homes & houses in Tuscumbia, AL. Invest wisely with VRBO & Tuscumbia, AL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Tuscumbia, AL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2055 KELLY Ln Tuscumbia, AL This home just feels right from the moment you walk in. The primary suite is on the main l...	5 beds \| 4 baths \| 4,200 sq.ft.	$465,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.7% Airbnb Rental Income: $null Traditional Rental Income: $3188 Airbnb ROI: N/A Traditional ROI: 5.7%
1009 Hemlock St Tuscumbia, AL Take a look at this beautiful 4-bedroom, 3-bath home located in the desirable Tuscumbia sc...	4 beds \| 3 baths \| 2,003 sq.ft.	$249,900	Airbnb cash on cash: 1.04% Traditional cash on cash: 6.55% Airbnb Rental Income: $1058 Traditional Rental Income: $1994 Airbnb ROI: 1.04% Traditional ROI: 6.55%
202 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$379,000	Airbnb cash on cash: -0.9% Traditional cash on cash: 5.68% Airbnb Rental Income: $582 Traditional Rental Income: $2638 Airbnb ROI: -0.9% Traditional ROI: 5.68%
703 E 2nd St Tuscumbia, AL Charming 1950s brick home located in the heart of Tuscumbia! This 3 bedroom, 2 bath home b...	3 beds \| 2 baths \| 1,673 sq.ft.	$237,500	Airbnb cash on cash: -0.41% Traditional cash on cash: 7.79% Airbnb Rental Income: $582 Traditional Rental Income: $2138 Airbnb ROI: -0.41% Traditional ROI: 7.79%
608 Eastman Ave Tuscumbia, AL Take a look at this stunning and spacious home situated on a corner lot in Tuscumbia. Ther...	3 beds \| 3 baths \| 2,300 sq.ft.	$339,900	Airbnb cash on cash: -0.67% Traditional cash on cash: 6.76% Airbnb Rental Income: $582 Traditional Rental Income: $2669 Airbnb ROI: -0.67% Traditional ROI: 6.76%
302 Fame Ave Tuscumbia, AL This newly constructed 3-bedroom, 2.5-bathroom modern tudor home is designed with elegant ...	3 beds \| 3 baths \| 2,320 sq.ft.	$395,000	Airbnb cash on cash: -0.92% Traditional cash on cash: 5.35% Airbnb Rental Income: $582 Traditional Rental Income: $2620 Airbnb ROI: -0.92% Traditional ROI: 5.35%
304 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$387,000	Airbnb cash on cash: -0.91% Traditional cash on cash: 5.56% Airbnb Rental Income: $582 Traditional Rental Income: $2647 Airbnb ROI: -0.91% Traditional ROI: 5.56%
1513 Joe Wheeler Dr Tuscumbia, AL Don't wait too long to see this charming house that has been updated inside as well as out...	2 beds \| 2 baths \| 1,600 sq.ft.	$159,900	Airbnb cash on cash: 2.27% Traditional cash on cash: 11.62% Airbnb Rental Income: $991 Traditional Rental Income: $2065 Airbnb ROI: 2.27% Traditional ROI: 11.62%
121 Fame Ave Tuscumbia, AL Brand New Home Under Construction- Customize it Your Way! This stunning 3-bedroom 3-bathro...	3 beds \| 3 baths \| 2,282 sq.ft.	$419,900	Airbnb cash on cash: -0.95% Traditional cash on cash: 4.74% Airbnb Rental Income: $582 Traditional Rental Income: $2534 Airbnb ROI: -0.95% Traditional ROI: 4.74%
306 Fame Ave Tuscumbia, AL New Construction Home in Sound Crossings- Muscle Shoals School District! Don?t miss this u...	5 beds \| 3 baths \| 2,889 sq.ft.	$592,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.49% Airbnb Rental Income: $null Traditional Rental Income: $2823 Airbnb ROI: N/A Traditional ROI: 3.49%
205 Fame Ave Tuscumbia, AL Come be a part of Muscle Shoals' newest planned community, Sound Crossing, located just 15...	3 beds \| 3 baths \| 2,320 sq.ft.	$395,500	Airbnb cash on cash: -0.86% Traditional cash on cash: 5.19% Airbnb Rental Income: $582 Traditional Rental Income: $2539 Airbnb ROI: -0.86% Traditional ROI: 5.19%
311 E 6th Street Tuscumbia, AL Step into one of Tuscumbia's most iconic homes - the "Heflin House." This nearly 4,000 sq ...	4 beds \| 3 baths \| 3,867 sq.ft.	$335,000	Airbnb cash on cash: 0.48% Traditional cash on cash: 8.38% Airbnb Rental Income: $1058 Traditional Rental Income: $3182 Airbnb ROI: 0.48% Traditional ROI: 8.38%
425 Cedar Hill Ln Tuscumbia, AL Listing agent is related to seller. Contingent upon Medicaid approval. Home to be sold "AS...	3 beds \| 2 baths \| 2,066 sq.ft.	$325,000	Airbnb cash on cash: -0.6% Traditional cash on cash: 5.86% Airbnb Rental Income: $582 Traditional Rental Income: $2271 Airbnb ROI: -0.6% Traditional ROI: 5.86%
804 E 7th St Tuscumbia, AL COMPLETELY RENOVATED from top to bottom, inside & out! Come see this charming 2 bedroom/1 ...	2 beds \| 1 baths \| 1,088 sq.ft.	$159,900	Airbnb cash on cash: 2.26% Traditional cash on cash: 6.86% Airbnb Rental Income: $991 Traditional Rental Income: $1339 Airbnb ROI: 2.26% Traditional ROI: 6.86%
1705 Keller Quarry Rd Tuscumbia, AL Charming 3 bedrooms, 2 bath home on 1 acre corner lot near Pickwick Lake. Freshly painted...	3 beds \| 2 baths \| 1,632 sq.ft.	$248,250	Airbnb cash on cash: -0.55% Traditional cash on cash: 6.65% Airbnb Rental Income: $582 Traditional Rental Income: $1984 Airbnb ROI: -0.55% Traditional ROI: 6.65%
710 N High St Tuscumbia, AL Check out this well maintained home in the heart of Tuscumbia. This spacious 3 bed, 1.5 ba...	3 beds \| 2 baths \| 1,300 sq.ft.	$168,400	Airbnb cash on cash: -0.15% Traditional cash on cash: 8.97% Airbnb Rental Income: $582 Traditional Rental Income: $1761 Airbnb ROI: -0.15% Traditional ROI: 8.97%
110 Emerald Dr Tuscumbia, AL Charming & move-in ready, this beautiful home with 3 bedrooms (1 bedroom is smaller; perfe...	3 beds \| 2 baths \| 1,513 sq.ft.	$189,900	Airbnb cash on cash: -0.49% Traditional cash on cash: 8.97% Airbnb Rental Income: $582 Traditional Rental Income: $2003 Airbnb ROI: -0.49% Traditional ROI: 8.97%
120 River Dr Tuscumbia, AL NEW DRIVEWAY AND LANDSCAPING! NEW OUTSIDE PICS! Here is your opportunity to live in the ...	3 beds \| 2 baths \| 2,425 sq.ft.	$213,900	Airbnb cash on cash: -0.41% Traditional cash on cash: 9.72% Airbnb Rental Income: $582 Traditional Rental Income: $2349 Airbnb ROI: -0.41% Traditional ROI: 9.72%
1101 Catalpa St Tuscumbia, AL Lovely 4 bedroom 2 bath house which sits on a .34 acre corner lot in a desirable neighbor...	4 beds \| 2 baths \| 1,835 sq.ft.	$232,000	Airbnb cash on cash: 1.37% Traditional cash on cash: 8.93% Airbnb Rental Income: $1058 Traditional Rental Income: $2352 Airbnb ROI: 1.37% Traditional ROI: 8.93%
1008 E 6th St Tuscumbia, AL Step into timeless charm at 1008 E 6th St in Historic Tuscumbia, AL! This classic two-stor...	3 beds \| 2 baths \| 2,277 sq.ft.	$209,900	Airbnb cash on cash: -0.39% Traditional cash on cash: 10.54% Airbnb Rental Income: $582 Traditional Rental Income: $2471 Airbnb ROI: -0.39% Traditional ROI: 10.54%
1001 N Cave St Tuscumbia, AL This charming 3 bedroom, 1 bath home is situated on a spacious corner lot and offers plent...	3 beds \| 1 baths \| 1,186 sq.ft.	$163,900	Airbnb cash on cash: 0.05% Traditional cash on cash: 8.56% Airbnb Rental Income: $582 Traditional Rental Income: $1627 Airbnb ROI: 0.05% Traditional ROI: 8.56%
1045 Carter Dr Tuscumbia, AL Looking For A Home With A Great Water View And Access? Your Search Is Over. Fish Or Swim ...	4 beds \| 4 baths \| 1,763 sq.ft.	$325,000	Airbnb cash on cash: 0.8% Traditional cash on cash: 6.13% Airbnb Rental Income: $1058 Traditional Rental Income: $2320 Airbnb ROI: 0.8% Traditional ROI: 6.13%
304 5th St Tuscumbia, AL Now is your chance to own your first rental property or add a cash flowing duplex to your ...	N/A beds \| N/A baths \| N/A	$199,900	Airbnb cash on cash: 1.31% Traditional cash on cash: 3.76% Airbnb Rental Income: $1058 Traditional Rental Income: $1157 Airbnb ROI: 1.31% Traditional ROI: 3.76%
406 N Commons St Tuscumbia, AL Located in a prime downtown Tuscumbia spot, this home sits on a corner lot with two parcel...	4 beds \| 3 baths \| 2,640 sq.ft.	$274,900	Airbnb cash on cash: 0.97% Traditional cash on cash: 11.09% Airbnb Rental Income: $1058 Traditional Rental Income: $3314 Airbnb ROI: 0.97% Traditional ROI: 11.09%
45 Sadie Lane Tuscumbia, AL Free Money up to 20,000 call for detail! Brand-new 1,528 sq ft cae 3-bed, 2-bath in Tuscum...	3 beds \| 2 baths \| 1,528 sq.ft.	$304,990	Airbnb cash on cash: -0.92% Traditional cash on cash: 5.42% Airbnb Rental Income: $582 Traditional Rental Income: $2117 Airbnb ROI: -0.92% Traditional ROI: 5.42%
85 Sadie Lane Tuscumbia, AL Up to 20K in savings call for details. Discover modern living in this new construction 1,4...	3 beds \| 2 baths \| 1,400 sq.ft.	$279,990	Airbnb cash on cash: -0.88% Traditional cash on cash: 5.6% Airbnb Rental Income: $582 Traditional Rental Income: $2006 Airbnb ROI: -0.88% Traditional ROI: 5.6%
125 Sadie Lane Tuscumbia, AL Up to 20K in savings/free money call for details! Discover this just-built 1,554 sq ft, 3-...	3 beds \| 2 baths \| 1,554 sq.ft.	$309,990	Airbnb cash on cash: -0.93% Traditional cash on cash: 5.29% Airbnb Rental Income: $582 Traditional Rental Income: $2109 Airbnb ROI: -0.93% Traditional ROI: 5.29%
160 Little Egypt Rd Tuscumbia, AL Charming mini farm with stocked pond, barn, and 4 large outbuildings. Country living at it...	3 beds \| 1 baths \| 1,465 sq.ft.	$213,000	Airbnb cash on cash: -0.1% Traditional cash on cash: 6.72% Airbnb Rental Income: $582 Traditional Rental Income: $1673 Airbnb ROI: -0.1% Traditional ROI: 6.72%
310 W 6th St Tuscumbia, AL 310 W. 6th St. in Tuscumbia is a charming 3-bedroom, 1-bath bungalow with pretty curb appe...	3 beds \| 1 baths \| 1,937 sq.ft.	$135,000	Airbnb cash on cash: -0.34% Traditional cash on cash: 11% Airbnb Rental Income: $582 Traditional Rental Income: $1766 Airbnb ROI: -0.34% Traditional ROI: 11%
1211 Anna Dr Tuscumbia, AL Welcome to Southern Elegance! A home that transcends the ordinaryâan exquisite 5-bedroom...	5 beds \| 5 baths \| 3,484 sq.ft.	$989,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $4921 Airbnb ROI: N/A Traditional ROI: 3.86%
1306 Calhoun St Tuscumbia, AL You will love this home located in Tuscumbia with the school options of Deshler or Colbert...	3 beds \| 2 baths \| 1,589 sq.ft.	$220,000	Airbnb cash on cash: -0.32% Traditional cash on cash: 8.33% Airbnb Rental Income: $582 Traditional Rental Income: $2098 Airbnb ROI: -0.32% Traditional ROI: 8.33%
911 Madison St Tuscumbia, AL Charming 2-bedroom, 1-bath home in the heart of Tuscumbia, AL! This inviting residence fea...	2 beds \| 2 baths \| 1,632 sq.ft.	$149,900	Airbnb cash on cash: 2.34% Traditional cash on cash: 8.17% Airbnb Rental Income: $991 Traditional Rental Income: $1473 Airbnb ROI: 2.34% Traditional ROI: 8.17%
2675 E 6th St Tuscumbia, AL Renovated 3 bedroom, 2 bath painted brick home situated on a spacious 1-acre lot in Muscle...	3 beds \| 2 baths \| 1,439 sq.ft.	$230,900	Airbnb cash on cash: -0.23% Traditional cash on cash: 7.18% Airbnb Rental Income: $582 Traditional Rental Income: $1915 Airbnb ROI: -0.23% Traditional ROI: 7.18%
304 W 1st Street Tuscumbia, AL Welcome home to this beautifully remodeled gem in the heart of downtown Tuscumbia. Taken d...	4 beds \| 2 baths \| 1,965 sq.ft.	$249,000	Airbnb cash on cash: 1.49% Traditional cash on cash: 8.97% Airbnb Rental Income: $1058 Traditional Rental Income: $2453 Airbnb ROI: 1.49% Traditional ROI: 8.97%
152 Harmony Dr Tuscumbia, AL Chic and move-in ready 4BR/2BA home, featuring an open-concept layout, tile floors through...	4 beds \| 2 baths \| 1,685 sq.ft.	$269,900	Airbnb cash on cash: 0.36% Traditional cash on cash: 6.03% Airbnb Rental Income: $1058 Traditional Rental Income: $2136 Airbnb ROI: 0.36% Traditional ROI: 6.03%
121 Walker Ave Tuscumbia, AL A touch of vintage with a modern vibe describes this beauty located in the quiet neighborh...	4 beds \| 2 baths \| 1,898 sq.ft.	$248,000	Airbnb cash on cash: 1.37% Traditional cash on cash: 9% Airbnb Rental Income: $1058 Traditional Rental Income: $2480 Airbnb ROI: 1.37% Traditional ROI: 9%
108 W Jackson St Tuscumbia, AL New roof coming soon !!!! Great Remodeled 3 bed 1 bath Cottage in the Heart of Tuscumbia ...	3 beds \| 1 baths \| 1,100 sq.ft.	$159,900	Airbnb cash on cash: -0.29% Traditional cash on cash: 6.03% Airbnb Rental Income: $582 Traditional Rental Income: $1262 Airbnb ROI: -0.29% Traditional ROI: 6.03%
435 Carter Dr Tuscumbia, AL Wake up to open views of the Tennessee River in a home where the water does most of the ta...	4 beds \| 3 baths \| 2,643 sq.ft.	$749,900	Airbnb cash on cash: -0.26% Traditional cash on cash: 2.56% Airbnb Rental Income: $1058 Traditional Rental Income: $2669 Airbnb ROI: -0.26% Traditional ROI: 2.56%
300 Fame Ave Tuscumbia, AL Muscle Shoals' newest planned community, Sound Crossing, has a home waiting for you and it...	3 beds \| 3 baths \| 2,976 sq.ft.	$525,500	Airbnb cash on cash: -1% Traditional cash on cash: 3.73% Airbnb Rental Income: $582 Traditional Rental Income: $2618 Airbnb ROI: -1% Traditional ROI: 3.73%
930 Twin Pines Cir Tuscumbia, AL Welcome to golf course living at its finest. This beautifully designed 4 bedroom, 2.5 bath...	4 beds \| 2 baths \| 2,800 sq.ft.	$389,900	Airbnb cash on cash: 0.27% Traditional cash on cash: 2.43% Airbnb Rental Income: $1058 Traditional Rental Income: $1484 Airbnb ROI: 0.27% Traditional ROI: 2.43%

Real Estate investment in Tuscumbia, AL

There are 58 properties for sale in the city of Tuscumbia . The median list price in Tuscumbia is $249,900 and the average price per square foot is $127. In April 2026, the average monthly cash on cash return in Tuscumbia is 7.00%. The average monthly rental income in Tuscumbia is $2,136.

Tuscumbia, AL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 58 investment properties available for sale in Tuscumbia.

In 2026, the best neighborhood to buy investment property is Tuscumbia.

The ROI for Short-Term is higher than the Long-Term in Tuscumbia with average rental income of $582.

Your search for investment property begins and ends here

Investment Property for Sale in Tuscumbia, AL

2055 KELLY Ln

Tuscumbia, AL

5 beds | 4 baths | 4,200 sq.ft.

$465,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.7%

Airbnb Rental Income: $null

Traditional Rental Income: $3188

Airbnb ROI: N/A

Traditional ROI: 5.7%

1009 Hemlock St

Tuscumbia, AL

4 beds | 3 baths | 2,003 sq.ft.

$249,900

Airbnb cash on cash: 1.04%

Traditional cash on cash: 6.55%

Airbnb Rental Income: $1058

Traditional Rental Income: $1994

Airbnb ROI: 1.04%

Traditional ROI: 6.55%

202 Fame Ave

Tuscumbia, AL

3 beds | 3 baths | 2,282 sq.ft.

$379,000

Airbnb cash on cash: -0.9%

Traditional cash on cash: 5.68%

Airbnb Rental Income: $582

Traditional Rental Income: $2638

Airbnb ROI: -0.9%

Traditional ROI: 5.68%

703 E 2nd St

Tuscumbia, AL

3 beds | 2 baths | 1,673 sq.ft.

$237,500

Airbnb cash on cash: -0.41%

Traditional cash on cash: 7.79%

Airbnb Rental Income: $582

Traditional Rental Income: $2138

Airbnb ROI: -0.41%

Traditional ROI: 7.79%

608 Eastman Ave

Tuscumbia, AL

3 beds | 3 baths | 2,300 sq.ft.

$339,900

Airbnb cash on cash: -0.67%

Traditional cash on cash: 6.76%

Airbnb Rental Income: $582

Traditional Rental Income: $2669

Airbnb ROI: -0.67%

Traditional ROI: 6.76%

302 Fame Ave

Tuscumbia, AL

3 beds | 3 baths | 2,320 sq.ft.

$395,000

Airbnb cash on cash: -0.92%

Traditional cash on cash: 5.35%

Airbnb Rental Income: $582

Traditional Rental Income: $2620

Airbnb ROI: -0.92%

Traditional ROI: 5.35%

304 Fame Ave

Tuscumbia, AL

3 beds | 3 baths | 2,282 sq.ft.

$387,000

Airbnb cash on cash: -0.91%

Traditional cash on cash: 5.56%

Airbnb Rental Income: $582

Traditional Rental Income: $2647

Airbnb ROI: -0.91%

Traditional ROI: 5.56%

1513 Joe Wheeler Dr

Tuscumbia, AL

2 beds | 2 baths | 1,600 sq.ft.

$159,900

Airbnb cash on cash: 2.27%

Traditional cash on cash: 11.62%

Airbnb Rental Income: $991

Traditional Rental Income: $2065

Airbnb ROI: 2.27%