Real Estate Investment Properties for Sale in Tuscumbia, AL

Looking for investment property in Tuscumbia, AL with high ROI ?

Explore a variety of short-term homes & houses in Tuscumbia, AL. Invest wisely with VRBO & Tuscumbia, AL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Tuscumbia, AL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
185 Valley Grove St Tuscumbia, AL Charming 3BR/2.5BA home in a prime Tuscumbia location, just minutes from Hwy 72 and Wilson...	3 beds \| 3 baths \| 1,825 sq.ft.	$429,900	Airbnb cash on cash: -0.02% Traditional cash on cash: 4.29% Airbnb Rental Income: $930 Traditional Rental Income: $2323 Airbnb ROI: -0.02% Traditional ROI: 4.29%
909 Irene Ave Tuscumbia, AL This updated 3 bedroom, 1 bath- home offers a fresh interior with modern touches throughou...	3 beds \| 1 baths \| 1,392 sq.ft.	$176,500	Airbnb cash on cash: 1.59% Traditional cash on cash: 7.97% Airbnb Rental Income: $930 Traditional Rental Income: $1658 Airbnb ROI: 1.59% Traditional ROI: 7.97%
720 Smith Ln Tuscumbia, AL Lovely four-bed home with a charming country appeal. Lots of updates, with a 5-year-old ro...	4 beds \| 2 baths \| 1,600 sq.ft.	$209,999	Airbnb cash on cash: 2.56% Traditional cash on cash: 3.97% Airbnb Rental Income: $1260 Traditional Rental Income: $1142 Airbnb ROI: 2.56% Traditional ROI: 3.97%
1446 Baker Ln Tuscumbia, AL Welcome to this beautifully crafted 5-bedroom, 2.5-bath brick home on almost a half acre l...	5 beds \| 3 baths \| 2,350 sq.ft.	$419,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.2% Airbnb Rental Income: $null Traditional Rental Income: $2637 Airbnb ROI: N/A Traditional ROI: 5.2%
1935 Ashton St Tuscumbia, AL This beautiful 4 bedroom, 3 bath home is located in the highly-desired Arrowhead Estates s...	4 beds \| 3 baths \| 2,993 sq.ft.	$480,000	Airbnb cash on cash: 0.46% Traditional cash on cash: 4.95% Airbnb Rental Income: $1260 Traditional Rental Income: $2878 Airbnb ROI: 0.46% Traditional ROI: 4.95%
1009 Hemlock St Tuscumbia, AL Take a look at this beautiful 4-bedroom, 3-bath home located in the desirable Tuscumbia sc...	4 beds \| 3 baths \| 2,003 sq.ft.	$246,900	Airbnb cash on cash: 1.78% Traditional cash on cash: 6.64% Airbnb Rental Income: $1260 Traditional Rental Income: $1994 Airbnb ROI: 1.78% Traditional ROI: 6.64%
208 Maclin Cir Tuscumbia, AL Custom built 3 bedroom, 2 full bath Florida style home with pool in convenient Tuscumbia n...	3 beds \| 2 baths \| 2,950 sq.ft.	$539,900	Airbnb cash on cash: -0.3% Traditional cash on cash: 2.84% Airbnb Rental Income: $930 Traditional Rental Income: $2169 Airbnb ROI: -0.3% Traditional ROI: 2.84%
608 Eastman Ave Tuscumbia, AL Take a look at this stunning and spacious home situated on a corner lot in Tuscumbia. Ther...	3 beds \| 3 baths \| 2,300 sq.ft.	$329,900	Airbnb cash on cash: 0.27% Traditional cash on cash: 6.99% Airbnb Rental Income: $930 Traditional Rental Income: $2669 Airbnb ROI: 0.27% Traditional ROI: 6.99%
304 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$387,000	Airbnb cash on cash: -0.11% Traditional cash on cash: 5.56% Airbnb Rental Income: $930 Traditional Rental Income: $2647 Airbnb ROI: -0.11% Traditional ROI: 5.56%
1540 Woodmont Dr Tuscumbia, AL You are going to fall in love with this completely remodeled farm house. Home features new...	3 beds \| 2 baths \| 1,150 sq.ft.	$189,500	Airbnb cash on cash: 1.64% Traditional cash on cash: 7.89% Airbnb Rental Income: $930 Traditional Rental Income: $1713 Airbnb ROI: 1.64% Traditional ROI: 7.89%
121 Fame Ave Tuscumbia, AL Brand New Home Under Construction- Customize it Your Way! This stunning 3-bedroom 3-bathro...	3 beds \| 3 baths \| 2,282 sq.ft.	$419,900	Airbnb cash on cash: -0.21% Traditional cash on cash: 4.74% Airbnb Rental Income: $930 Traditional Rental Income: $2534 Airbnb ROI: -0.21% Traditional ROI: 4.74%
306 Fame Ave Tuscumbia, AL New Construction Home in Sound Crossings- Muscle Shoals School District! Don?t miss this u...	5 beds \| 3 baths \| 2,889 sq.ft.	$592,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.49% Airbnb Rental Income: $null Traditional Rental Income: $2823 Airbnb ROI: N/A Traditional ROI: 3.49%
205 Fame Ave Tuscumbia, AL Come be a part of Muscle Shoals' newest planned community, Sound Crossing, located just 15...	3 beds \| 3 baths \| 2,320 sq.ft.	$395,500	Airbnb cash on cash: -0.08% Traditional cash on cash: 5.19% Airbnb Rental Income: $930 Traditional Rental Income: $2539 Airbnb ROI: -0.08% Traditional ROI: 5.19%
311 E 6th St Tuscumbia, AL This historic property, known as the "Heflin House," is located in Downtown Tuscumbia and ...	4 beds \| 3 baths \| 3,867 sq.ft.	$345,000	Airbnb cash on cash: 0.92% Traditional cash on cash: 8.08% Airbnb Rental Income: $1260 Traditional Rental Income: $3182 Airbnb ROI: 0.92% Traditional ROI: 8.08%
1705 Keller Quarry Rd Tuscumbia, AL Charming 3 bedrooms, 2 bath home on 1 acre corner lot near Pickwick Lake. Freshly painted ...	3 beds \| 2 baths \| 1,632 sq.ft.	$239,000	Airbnb cash on cash: 0.77% Traditional cash on cash: 6.96% Airbnb Rental Income: $930 Traditional Rental Income: $1984 Airbnb ROI: 0.77% Traditional ROI: 6.96%
120 River Dr Tuscumbia, AL NEW DRIVEWAY AND LANDSCAPING! NEW OUTSIDE PICS! Here is your opportunity to live in the ...	3 beds \| 2 baths \| 2,425 sq.ft.	$203,900	Airbnb cash on cash: 1.13% Traditional cash on cash: 10.25% Airbnb Rental Income: $930 Traditional Rental Income: $2349 Airbnb ROI: 1.13% Traditional ROI: 10.25%
1101 Catalpa St Tuscumbia, AL Welcome to this charming 4 bedroom, 2 bath home located on corner lot in a desirable neigh...	4 beds \| 2 baths \| 1,835 sq.ft.	$229,000	Airbnb cash on cash: 2.18% Traditional cash on cash: 9.06% Airbnb Rental Income: $1260 Traditional Rental Income: $2352 Airbnb ROI: 2.18% Traditional ROI: 9.06%
1008 E 6th St Tuscumbia, AL Step into timeless charm at 1008 E 6th St in Historic Tuscumbia, AL! This classic two-stor...	3 beds \| 2 baths \| 2,277 sq.ft.	$200,000	Airbnb cash on cash: 1.16% Traditional cash on cash: 11.09% Airbnb Rental Income: $930 Traditional Rental Income: $2471 Airbnb ROI: 1.16% Traditional ROI: 11.09%
1001 N Cave St Tuscumbia, AL This charming 3 bedroom, 1 bath home is situated on a spacious corner lot and offers plent...	3 beds \| 1 baths \| 1,186 sq.ft.	$163,900	Airbnb cash on cash: 1.9% Traditional cash on cash: 8.56% Airbnb Rental Income: $930 Traditional Rental Income: $1627 Airbnb ROI: 1.9% Traditional ROI: 8.56%
45 Sadie Lane Tuscumbia, AL Smart buyer alert. Score $20,000 in free money plus a 4.5% interest rate with our preferre...	3 beds \| 2 baths \| 1,528 sq.ft.	$299,990	Airbnb cash on cash: 0.12% Traditional cash on cash: 5.54% Airbnb Rental Income: $930 Traditional Rental Income: $2117 Airbnb ROI: 0.12% Traditional ROI: 5.54%
85 Sadie Lane Tuscumbia, AL First and second time buyers, this is your moment. $20,000 in free money plus a 4.5% inter...	3 beds \| 2 baths \| 1,400 sq.ft.	$272,990	Airbnb cash on cash: 0.26% Traditional cash on cash: 5.78% Airbnb Rental Income: $930 Traditional Rental Income: $2006 Airbnb ROI: 0.26% Traditional ROI: 5.78%
1306 Calhoun St Tuscumbia, AL Welcome home to this beautifully updated brick ranch featuring an open and inviting floor ...	3 beds \| 2 baths \| 1,589 sq.ft.	$217,500	Airbnb cash on cash: 1.07% Traditional cash on cash: 8.41% Airbnb Rental Income: $930 Traditional Rental Income: $2098 Airbnb ROI: 1.07% Traditional ROI: 8.41%
505 Osborn Hill Rd Tuscumbia, AL Priced $33,000 under tax appraisal! Experience country living with modern touches in this ...	3 beds \| 2 baths \| 3,118 sq.ft.	$339,990	Airbnb cash on cash: 0.13% Traditional cash on cash: 6.49% Airbnb Rental Income: $930 Traditional Rental Income: $2617 Airbnb ROI: 0.13% Traditional ROI: 6.49%
2675 E 6th St Tuscumbia, AL Renovated 3 bedroom, 2 bath painted brick home situated on a spacious 1-acre lot in Muscle...	3 beds \| 2 baths \| 1,439 sq.ft.	$230,900	Airbnb cash on cash: 1.1% Traditional cash on cash: 7.18% Airbnb Rental Income: $930 Traditional Rental Income: $1915 Airbnb ROI: 1.1% Traditional ROI: 7.18%
105 Studio Dr Tuscumbia, AL 105 Studio Dr, Tuscumbia, AL 35674 \| Other	N/A beds \| N/A baths \| N/A	$89,000	Airbnb cash on cash: 1.46% Traditional cash on cash: 5.16% Airbnb Rental Income: $667 Traditional Rental Income: $689 Airbnb ROI: 1.46% Traditional ROI: 5.16%
103 Studio Dr Tuscumbia, AL 103 Studio Dr, Tuscumbia, AL 35674 \| Other	N/A beds \| N/A baths \| N/A	$89,000	Airbnb cash on cash: 1.46% Traditional cash on cash: 6.26% Airbnb Rental Income: $667 Traditional Rental Income: $785 Airbnb ROI: 1.46% Traditional ROI: 6.26%
107 Studio Dr Tuscumbia, AL 107 Studio Dr, Tuscumbia, AL 35674 \| Other	N/A beds \| N/A baths \| N/A	$89,000	Airbnb cash on cash: 1.46% Traditional cash on cash: 5.14% Airbnb Rental Income: $667 Traditional Rental Income: $687 Airbnb ROI: 1.46% Traditional ROI: 5.14%
121 Walker Ave Tuscumbia, AL MOTIVATED SELLERS!! ALL REASONABLE OFFERS WILL BE CONSIDERED!! A touch of vintage with a m...	4 beds \| 2 baths \| 1,898 sq.ft.	$234,900	Airbnb cash on cash: 2.26% Traditional cash on cash: 9.55% Airbnb Rental Income: $1260 Traditional Rental Income: $2480 Airbnb ROI: 2.26% Traditional ROI: 9.55%
108 W Jackson St Tuscumbia, AL New roof coming soon !!!! Great Remodeled 3 bed 1 bath Cottage in the Heart of Tuscumbia o...	3 beds \| 1 baths \| 1,100 sq.ft.	$154,900	Airbnb cash on cash: 1.69% Traditional cash on cash: 6.25% Airbnb Rental Income: $930 Traditional Rental Income: $1262 Airbnb ROI: 1.69% Traditional ROI: 6.25%
435 Carter Dr Tuscumbia, AL Wake up to open views of the Tennessee River in a home where the water does most of the ta...	4 beds \| 3 baths \| 2,643 sq.ft.	$649,999	Airbnb cash on cash: 0.12% Traditional cash on cash: 3.11% Airbnb Rental Income: $1260 Traditional Rental Income: $2669 Airbnb ROI: 0.12% Traditional ROI: 3.11%
300 Fame Ave Tuscumbia, AL Muscle Shoals' newest planned community, Sound Crossing, has a home waiting for you and it...	3 beds \| 3 baths \| 2,976 sq.ft.	$525,500	Airbnb cash on cash: -0.41% Traditional cash on cash: 3.73% Airbnb Rental Income: $930 Traditional Rental Income: $2618 Airbnb ROI: -0.41% Traditional ROI: 3.73%
1227 Twin Pines Cir Tuscumbia, AL Welcome home to this beautiful custom built brick estate constructed on a spacious half-ac...	4 beds \| 3 baths \| 2,438 sq.ft.	$450,000	Airbnb cash on cash: 0.43% Traditional cash on cash: 4.61% Airbnb Rental Income: $1260 Traditional Rental Income: $2624 Airbnb ROI: 0.43% Traditional ROI: 4.61%
811 Rebel Dr Tuscumbia, AL Spacious 3 bedroom, 2 bath brick ranch offering approximately 1,800 sq ft of one-level liv...	3 beds \| 2 baths \| 1,800 sq.ft.	$204,900	Airbnb cash on cash: 1.12% Traditional cash on cash: 9.18% Airbnb Rental Income: $930 Traditional Rental Income: $2152 Airbnb ROI: 1.12% Traditional ROI: 9.18%
904 E 1st St Tuscumbia, AL Charming 2 bedroom, 1 bath cottage located in Tuscumbia! This cozy home features low-maint...	2 beds \| 1 baths \| 1,191 sq.ft.	$124,500	Airbnb cash on cash: 4.25% Traditional cash on cash: 11.92% Airbnb Rental Income: $1187 Traditional Rental Income: $1719 Airbnb ROI: 4.25% Traditional ROI: 11.92%
1012 1st St Tuscumbia, AL Charming home in Tuscumbia remodeled and move in ready! This adorable home offers new roof...	2 beds \| 1 baths \| 1,130 sq.ft.	$189,900	Airbnb cash on cash: 2.68% Traditional cash on cash: 7.06% Airbnb Rental Income: $1187 Traditional Rental Income: $1591 Airbnb ROI: 2.68% Traditional ROI: 7.06%
190 Scogin Drive Tuscumbia, AL Welcome home to this beautifully updated 4-bedroom, 2-bath gem, perfectly situated on a ni...	4 beds \| 2 baths \| 2,321 sq.ft.	$315,000	Airbnb cash on cash: 1.18% Traditional cash on cash: 5.98% Airbnb Rental Income: $1260 Traditional Rental Income: $2284 Airbnb ROI: 1.18% Traditional ROI: 5.98%
217 Carron Ln Tuscumbia, AL This stunning contemporary home blends modern design with everyday comfort. Featuring 4 sp...	4 beds \| 4 baths \| 3,336 sq.ft.	$709,900	Airbnb cash on cash: -0.28% Traditional cash on cash: 3.06% Airbnb Rental Income: $1260 Traditional Rental Income: $3072 Airbnb ROI: -0.28% Traditional ROI: 3.06%
771 River Ln Tuscumbia, AL Up to 20K in savings/free money call for details. Breathtaking river views without the has...	3 beds \| 2 baths \| 1,200 sq.ft.	$239,990	Airbnb cash on cash: 0.76% Traditional cash on cash: 5.84% Airbnb Rental Income: $930 Traditional Rental Income: $1737 Airbnb ROI: 0.76% Traditional ROI: 5.84%
904 Irene St Tuscumbia, AL Looking for an affordable home in a great location? This charming 3 bedroom, 1 Bath home i...	2 beds \| 1 baths \| 1,050 sq.ft.	$132,500	Airbnb cash on cash: 4.14% Traditional cash on cash: 7.96% Airbnb Rental Income: $1187 Traditional Rental Income: $1287 Airbnb ROI: 4.14% Traditional ROI: 7.96%
304 W 3rd St Tuscumbia, AL Cashing Flowing Investment Alert! This 5-unit building is an excellent investment for any ...	N/A beds \| N/A baths \| N/A	$340,000	Airbnb cash on cash: -0.42% Traditional cash on cash: 3.06% Airbnb Rental Income: $667 Traditional Rental Income: $1477 Airbnb ROI: -0.42% Traditional ROI: 3.06%

Real Estate investment in Tuscumbia, AL

There are 75 properties for sale in the city of Tuscumbia . The median list price in Tuscumbia is $224,884 and the average price per square foot is $116. In June 2026, the average monthly cash on cash return in Tuscumbia is 6.00%. The average monthly rental income in Tuscumbia is $2,137.

Tuscumbia, AL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 75 investment properties available for sale in Tuscumbia.

In 2026, the best neighborhood to buy investment property is Tuscumbia.

The ROI for Long-Term is higher than the Short-Term in Tuscumbia with average rental income of $2,137.

Your search for investment property begins and ends here

Investment Property for Sale in Tuscumbia, AL

185 Valley Grove St

Tuscumbia, AL

3 beds | 3 baths | 1,825 sq.ft.

$429,900

Airbnb cash on cash: -0.02%

Traditional cash on cash: 4.29%

Airbnb Rental Income: $930

Traditional Rental Income: $2323

Airbnb ROI: -0.02%

Traditional ROI: 4.29%

909 Irene Ave

Tuscumbia, AL

3 beds | 1 baths | 1,392 sq.ft.

$176,500

Airbnb cash on cash: 1.59%

Traditional cash on cash: 7.97%

Airbnb Rental Income: $930

Traditional Rental Income: $1658

Airbnb ROI: 1.59%

Traditional ROI: 7.97%

720 Smith Ln

Tuscumbia, AL

4 beds | 2 baths | 1,600 sq.ft.

$209,999

Airbnb cash on cash: 2.56%

Traditional cash on cash: 3.97%

Airbnb Rental Income: $1260

Traditional Rental Income: $1142

Airbnb ROI: 2.56%

Traditional ROI: 3.97%

1446 Baker Ln

Tuscumbia, AL

5 beds | 3 baths | 2,350 sq.ft.

$419,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.2%

Airbnb Rental Income: $null

Traditional Rental Income: $2637

Airbnb ROI: N/A

Traditional ROI: 5.2%

1935 Ashton St

Tuscumbia, AL

4 beds | 3 baths | 2,993 sq.ft.

$480,000

Airbnb cash on cash: 0.46%

Traditional cash on cash: 4.95%

Airbnb Rental Income: $1260

Traditional Rental Income: $2878

Airbnb ROI: 0.46%

Traditional ROI: 4.95%

1009 Hemlock St

Tuscumbia, AL

4 beds | 3 baths | 2,003 sq.ft.

$246,900

Airbnb cash on cash: 1.78%

Traditional cash on cash: 6.64%

Airbnb Rental Income: $1260

Traditional Rental Income: $1994

Airbnb ROI: 1.78%

Traditional ROI: 6.64%

208 Maclin Cir

Tuscumbia, AL

3 beds | 2 baths | 2,950 sq.ft.

$539,900

Airbnb cash on cash: -0.3%

Traditional cash on cash: 2.84%

Airbnb Rental Income: $930

Traditional Rental Income: $2169

Airbnb ROI: -0.3%

Traditional ROI: 2.84%

608 Eastman Ave

Tuscumbia, AL

3 beds | 3 baths | 2,300 sq.ft.

$329,900

Airbnb cash on cash: 0.27%

Traditional cash on cash: 6.99%

Airbnb Rental Income: $930

Traditional Rental Income: $2669

Airbnb ROI: 0.27%