Real Estate Investment Properties for Sale in Tuscumbia, AL

Looking for investment property in Tuscumbia, AL with high ROI ?

Explore a variety of short-term homes & houses in Tuscumbia, AL. Invest wisely with VRBO & Tuscumbia, AL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Tuscumbia, AL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2055 KELLY Ln Tuscumbia, AL This home just feels right from the moment you walk in. The primary suite is on the main l...	5 beds \| 4 baths \| 4,200 sq.ft.	$475,000	Airbnb cash on cash: 3.07% Traditional cash on cash: 5.56% Airbnb Rental Income: $2726 Traditional Rental Income: $3188 Airbnb ROI: 3.07% Traditional ROI: 5.56%
280 New Bethel Rd Tuscumbia, AL New Listing â 280 New Bethel Road, Tuscumbia Welcome home to this beautifully remodeled...	3 beds \| 2 baths \| 1,436 sq.ft.	$259,500	Airbnb cash on cash: 3.34% Traditional cash on cash: 8.66% Airbnb Rental Income: $1688 Traditional Rental Income: $2520 Airbnb ROI: 3.34% Traditional ROI: 8.66%
275 Osborn Hill Rd Tuscumbia, AL Charming one bedroom, one bath garage apartment featuring an open concept living, dining a...	1 beds \| 1 baths \| 1,536 sq.ft.	$169,900	Airbnb cash on cash: 2.69% Traditional cash on cash: 8.01% Airbnb Rental Income: $1118 Traditional Rental Income: $1605 Airbnb ROI: 2.69% Traditional ROI: 8.01%
304 Maple St Tuscumbia, AL Charming 4-Bedroom Home on Expansive Lot! Welcome to 304 Maple St., a spacious 2,664 sq. f...	4 beds \| 2 baths \| 2,664 sq.ft.	$219,900	Airbnb cash on cash: 3.61% Traditional cash on cash: 10.39% Airbnb Rental Income: $1603 Traditional Rental Income: $2559 Airbnb ROI: 3.61% Traditional ROI: 10.39%
804 Volunteer Dr Tuscumbia, AL This spacious 3 bedroom 2 bath home has it all. Featuring updates throughout, a beautiful ...	3 beds \| 2 baths \| 2,094 sq.ft.	$259,000	Airbnb cash on cash: 3.09% Traditional cash on cash: 4.66% Airbnb Rental Income: $1688 Traditional Rental Income: $1601 Airbnb ROI: 3.09% Traditional ROI: 4.66%
105 Fieldwood Dr Tuscumbia, AL Where Summer Evenings Turn Into Forever Memories Imagine coming home to a timeless brick ...	4 beds \| 2 baths \| 2,193 sq.ft.	$479,900	Airbnb cash on cash: 0.95% Traditional cash on cash: 2.59% Airbnb Rental Income: $1603 Traditional Rental Income: $1881 Airbnb ROI: 0.95% Traditional ROI: 2.59%
202 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$430,000	Airbnb cash on cash: 1.33% Traditional cash on cash: 4.85% Airbnb Rental Income: $1688 Traditional Rental Income: $2638 Airbnb ROI: 1.33% Traditional ROI: 4.85%
608 Eastman Ave Tuscumbia, AL Take a look at this stunning and spacious home situated on a corner lot in Tuscumbia. Ther...	3 beds \| 3 baths \| 2,300 sq.ft.	$339,900	Airbnb cash on cash: 2.21% Traditional cash on cash: 6.76% Airbnb Rental Income: $1688 Traditional Rental Income: $2669 Airbnb ROI: 2.21% Traditional ROI: 6.76%
800 E 5th St Tuscumbia, AL Discover timeless charm in this stunning ranch-style home, perfectly situated just minutes...	4 beds \| 3 baths \| 2,903 sq.ft.	$299,900	Airbnb cash on cash: 2.47% Traditional cash on cash: 9.48% Airbnb Rental Income: $1603 Traditional Rental Income: $3124 Airbnb ROI: 2.47% Traditional ROI: 9.48%
302 Fame Ave Tuscumbia, AL This newly constructed 3-bedroom, 2.5-bathroom modern tudor home is designed with elegant ...	3 beds \| 3 baths \| 2,320 sq.ft.	$455,000	Airbnb cash on cash: 1.18% Traditional cash on cash: 4.47% Airbnb Rental Income: $1688 Traditional Rental Income: $2620 Airbnb ROI: 1.18% Traditional ROI: 4.47%
304 Fame Ave Tuscumbia, AL New Construction Home for Sale. Currently under construction in the new development Sound ...	3 beds \| 3 baths \| 2,282 sq.ft.	$447,000	Airbnb cash on cash: 1.22% Traditional cash on cash: 4.64% Airbnb Rental Income: $1688 Traditional Rental Income: $2647 Airbnb ROI: 1.22% Traditional ROI: 4.64%
1513 Joe Wheeler Dr Tuscumbia, AL Don't wait too long to see this charming house that has been updated inside as well as out...	2 beds \| 2 baths \| 1,600 sq.ft.	$159,900	Airbnb cash on cash: 4.89% Traditional cash on cash: 11.62% Airbnb Rental Income: $1472 Traditional Rental Income: $2065 Airbnb ROI: 4.89% Traditional ROI: 11.62%
121 Fame Ave Tuscumbia, AL Brand New Home Under Construction- Customize it Your Way! This stunning 3-bedroom 3-bathro...	3 beds \| 3 baths \| 2,282 sq.ft.	$479,900	Airbnb cash on cash: 1.05% Traditional cash on cash: 3.98% Airbnb Rental Income: $1688 Traditional Rental Income: $2534 Airbnb ROI: 1.05% Traditional ROI: 3.98%
306 Fame Ave Tuscumbia, AL New Construction Home in Sound Crossings- Muscle Shoals School District! Don?t miss this u...	5 beds \| 3 baths \| 2,889 sq.ft.	$652,000	Airbnb cash on cash: 1.82% Traditional cash on cash: 3.04% Airbnb Rental Income: $2726 Traditional Rental Income: $2823 Airbnb ROI: 1.82% Traditional ROI: 3.04%
205 Fame Ave Tuscumbia, AL Come be a part of Muscle Shoals' newest planned community, Sound Crossing. This home is fu...	3 beds \| 3 baths \| 2,320 sq.ft.	$455,600	Airbnb cash on cash: 1.23% Traditional cash on cash: 4.33% Airbnb Rental Income: $1688 Traditional Rental Income: $2539 Airbnb ROI: 1.23% Traditional ROI: 4.33%
311 E 6th Street Tuscumbia, AL Step into one of Tuscumbiaâs most iconic homes â the âHeflin House.â This nearly 4...	4 beds \| 3 baths \| 3,867 sq.ft.	$340,000	Airbnb cash on cash: 1.88% Traditional cash on cash: 8.25% Airbnb Rental Income: $1603 Traditional Rental Income: $3182 Airbnb ROI: 1.88% Traditional ROI: 8.25%
889 Blake Dr Tuscumbia, AL Welcome Home to this full brick beauty offering approximately 7200+/- square feet of the p...	5 beds \| 6 baths \| 7,202 sq.ft.	$825,000	Airbnb cash on cash: 1.36% Traditional cash on cash: 6.96% Airbnb Rental Income: $2726 Traditional Rental Income: $6385 Airbnb ROI: 1.36% Traditional ROI: 6.96%
425 Cedar Hill Ln Tuscumbia, AL Listing agent is related to seller. Contingent upon Medicaid approval. Home to be sold "AS...	3 beds \| 2 baths \| 2,066 sq.ft.	$325,000	Airbnb cash on cash: 2.41% Traditional cash on cash: 5.86% Airbnb Rental Income: $1688 Traditional Rental Income: $2271 Airbnb ROI: 2.41% Traditional ROI: 5.86%
1100 Raintree Dr Tuscumbia, AL PRICE ADJUSTMENT! You will love this beautiful home sitting on almost one acre in rural Tu...	4 beds \| 3 baths \| 3,876 sq.ft.	$419,000	Airbnb cash on cash: 1.42% Traditional cash on cash: 5.52% Airbnb Rental Income: $1603 Traditional Rental Income: $2758 Airbnb ROI: 1.42% Traditional ROI: 5.52%
1705 Keller Quarry Rd Tuscumbia, AL Charming 3 bedrooms, 2 bath home on 1 acre corner lot near Pickwick Lake. Freshly painted...	3 beds \| 2 baths \| 1,632 sq.ft.	$248,500	Airbnb cash on cash: 3.38% Traditional cash on cash: 6.64% Airbnb Rental Income: $1688 Traditional Rental Income: $1984 Airbnb ROI: 3.38% Traditional ROI: 6.64%
710 N High St Tuscumbia, AL Check out this well maintained home in the heart of Tuscumbia. This spacious 3 bed, 1.5 ba...	3 beds \| 2 baths \| 1,300 sq.ft.	$169,900	Airbnb cash on cash: 5.53% Traditional cash on cash: 8.89% Airbnb Rental Income: $1688 Traditional Rental Income: $1761 Airbnb ROI: 5.53% Traditional ROI: 8.89%
120 River Dr Tuscumbia, AL NEW DRIVEWAY AND LANDSCAPING! NEW OUTSIDE PICS! Here is your opportunity to live in the ...	3 beds \| 2 baths \| 2,425 sq.ft.	$223,900	Airbnb cash on cash: 3.9% Traditional cash on cash: 9.23% Airbnb Rental Income: $1688 Traditional Rental Income: $2349 Airbnb ROI: 3.9% Traditional ROI: 9.23%
1101 Catalpa St Tuscumbia, AL Lovely 4 bedroom 2 bath house which sits on a .34 acre corner lot in a desirable neighbor...	4 beds \| 2 baths \| 1,835 sq.ft.	$232,000	Airbnb cash on cash: 3.44% Traditional cash on cash: 8.93% Airbnb Rental Income: $1603 Traditional Rental Income: $2352 Airbnb ROI: 3.44% Traditional ROI: 8.93%
1008 E 6th St Tuscumbia, AL Step into timeless charm at 1008 E 6th St in Historic Tuscumbia, AL! This classic two-stor...	3 beds \| 2 baths \| 2,277 sq.ft.	$219,900	Airbnb cash on cash: 4.01% Traditional cash on cash: 10.02% Airbnb Rental Income: $1688 Traditional Rental Income: $2471 Airbnb ROI: 4.01% Traditional ROI: 10.02%
709 Joe Wheeler Dr Tuscumbia, AL Welcome to this charming cottage located in Tuscumbia ! This pristine 3-bedroom, 2-bathro...	3 beds \| 2 baths \| 1,104 sq.ft.	$210,900	Airbnb cash on cash: 4.55% Traditional cash on cash: 8.84% Airbnb Rental Income: $1688 Traditional Rental Income: $2074 Airbnb ROI: 4.55% Traditional ROI: 8.84%
1001 N Cave St Tuscumbia, AL This charming 3 bedroom, 1 bath home is situated on a spacious corner lot and offers plent...	3 beds \| 1 baths \| 1,186 sq.ft.	$164,900	Airbnb cash on cash: 5.91% Traditional cash on cash: 8.51% Airbnb Rental Income: $1688 Traditional Rental Income: $1627 Airbnb ROI: 5.91% Traditional ROI: 8.51%
807 Rebel Dr Tuscumbia, AL Charming 3-bedroom, 2-bath home in Tuscumbia city limits! This home features a spacious ki...	3 beds \| 2 baths \| 2,500 sq.ft.	$289,000	Airbnb cash on cash: 2.75% Traditional cash on cash: 7.19% Airbnb Rental Income: $1688 Traditional Rental Income: $2426 Airbnb ROI: 2.75% Traditional ROI: 7.19%
1229 Huntington Ln Tuscumbia, AL Gorgeous home with outstanding finishes and a recent update. 3 beds, 2.5 baths, office, bo...	3 beds \| 3 baths \| 2,500 sq.ft.	$429,000	Airbnb cash on cash: 1.43% Traditional cash on cash: 4.81% Airbnb Rental Income: $1688 Traditional Rental Income: $2574 Airbnb ROI: 1.43% Traditional ROI: 4.81%
304 5th St Tuscumbia, AL Now is your chance to own your first rental property or add a cash flowing duplex to your ...	N/A beds \| N/A baths \| N/A	$209,999	Airbnb cash on cash: 3.84% Traditional cash on cash: 3.53% Airbnb Rental Income: $1688 Traditional Rental Income: $1157 Airbnb ROI: 3.84% Traditional ROI: 3.53%
406 N Commons St Tuscumbia, AL Located in a prime downtown Tuscumbia spot, this home sits on a corner lot with two parcel...	4 beds \| 3 baths \| 2,640 sq.ft.	$304,900	Airbnb cash on cash: 2.36% Traditional cash on cash: 9.92% Airbnb Rental Income: $1603 Traditional Rental Income: $3314 Airbnb ROI: 2.36% Traditional ROI: 9.92%
302 W 6th St Tuscumbia, AL TWO HOUSES!! The welcoming front porch sets the tone for this homeâs southern charm-perf...	4 beds \| 2 baths \| 2,097 sq.ft.	$285,900	Airbnb cash on cash: 2.45% Traditional cash on cash: 8.7% Airbnb Rental Income: $1603 Traditional Rental Income: $2829 Airbnb ROI: 2.45% Traditional ROI: 8.7%
15 Sadie Lane Tuscumbia, AL Welcome to your stunning new 1,400 sq ft, 3-bed, 2-bath masterpiece in Tuscumbia, ALâwhe...	3 beds \| 2 baths \| 1,400 sq.ft.	$279,990	Airbnb cash on cash: 2.61% Traditional cash on cash: 5.6% Airbnb Rental Income: $1688 Traditional Rental Income: $2006 Airbnb ROI: 2.61% Traditional ROI: 5.6%
45 Sadie Lane Tuscumbia, AL Brand-new 1,528 sq ft cae 3-bed, 2-bath in Tuscumbia, AL. Open-concept with vaulted ceilin...	3 beds \| 2 baths \| 1,528 sq.ft.	$304,990	Airbnb cash on cash: 2.29% Traditional cash on cash: 5.42% Airbnb Rental Income: $1688 Traditional Rental Income: $2117 Airbnb ROI: 2.29% Traditional ROI: 5.42%
85 Sadie Lane Tuscumbia, AL Discover modern living in this new construction 1,400 sq ft, 3-bed, 2-bath home in the hea...	3 beds \| 2 baths \| 1,400 sq.ft.	$279,990	Airbnb cash on cash: 2.61% Traditional cash on cash: 5.6% Airbnb Rental Income: $1688 Traditional Rental Income: $2006 Airbnb ROI: 2.61% Traditional ROI: 5.6%
125 Sadie Lane Tuscumbia, AL Discover this just-built 1,554 sq ft, 3-bed, 2-bath gem on a huge 0.31-acre lot in a brand...	3 beds \| 2 baths \| 1,554 sq.ft.	$309,990	Airbnb cash on cash: 2.23% Traditional cash on cash: 5.29% Airbnb Rental Income: $1688 Traditional Rental Income: $2109 Airbnb ROI: 2.23% Traditional ROI: 5.29%
3365 Hickerson Ave Tuscumbia, AL PROBATE SELL. BEAUTIFUL BRICK RANCH STYLE HOME. 1648 SQ FT. 3 BED, 2 BATH. NEW HVAC SYSTEM...	3 beds \| 2 baths \| 1,648 sq.ft.	$248,000	Airbnb cash on cash: 3.39% Traditional cash on cash: 6.97% Airbnb Rental Income: $1688 Traditional Rental Income: $2057 Airbnb ROI: 3.39% Traditional ROI: 6.97%
160 Little Egypt Rd Tuscumbia, AL Charming mini farm with stocked pond, barn, and 4 large outbuildings. Country living at it...	3 beds \| 1 baths \| 1,465 sq.ft.	$213,000	Airbnb cash on cash: 4.47% Traditional cash on cash: 6.72% Airbnb Rental Income: $1688 Traditional Rental Income: $1673 Airbnb ROI: 4.47% Traditional ROI: 6.72%
209 2nd Avenue Tuscumbia, AL Attention Investors! This property is part of a 4-home investment portfolio, all currently...	3 beds \| 1 baths \| 1,050 sq.ft.	$350,000	Airbnb cash on cash: 2.34% Traditional cash on cash: 3.55% Airbnb Rental Income: $1688 Traditional Rental Income: $1616 Airbnb ROI: 2.34% Traditional ROI: 3.55%
1110 Shirley Dr Tuscumbia, AL SELLERS WILL PAY BUYER'S CLOSING COSTS! Nice remodeled house that is ready for a new owner...	3 beds \| 1 baths \| 1,000 sq.ft.	$109,999	Airbnb cash on cash: 9.07% Traditional cash on cash: 11.61% Airbnb Rental Income: $1688 Traditional Rental Income: $1489 Airbnb ROI: 9.07% Traditional ROI: 11.61%
1211 Anna Dr Tuscumbia, AL Welcome to Southern Elegance! A home that transcends the ordinaryâan exquisite 5-bedroom...	5 beds \| 5 baths \| 3,484 sq.ft.	$995,500	Airbnb cash on cash: 0.77% Traditional cash on cash: 3.84% Airbnb Rental Income: $2726 Traditional Rental Income: $4921 Airbnb ROI: 0.77% Traditional ROI: 3.84%

Real Estate investment in Tuscumbia, AL

There are 70 properties for sale in the city of Tuscumbia . The median list price in Tuscumbia is $259,250 and the average price per square foot is $124. In February 2026, the average monthly cash on cash return in Tuscumbia is 7.00%. The average monthly rental income in Tuscumbia is $2,117.

Tuscumbia, AL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 70 investment properties available for sale in Tuscumbia.

In 2026, the best neighborhood to buy investment property is Tuscumbia.

The ROI for Long-Term is higher than the Short-Term in Tuscumbia with average rental income of $2,117.

Your search for investment property begins and ends here

Investment Property for Sale in Tuscumbia, AL

2055 KELLY Ln

Tuscumbia, AL

5 beds | 4 baths | 4,200 sq.ft.

$475,000

Airbnb cash on cash: 3.07%

Traditional cash on cash: 5.56%

Airbnb Rental Income: $2726

Traditional Rental Income: $3188

Airbnb ROI: 3.07%

Traditional ROI: 5.56%

280 New Bethel Rd

Tuscumbia, AL

3 beds | 2 baths | 1,436 sq.ft.

$259,500

Airbnb cash on cash: 3.34%

Traditional cash on cash: 8.66%

Airbnb Rental Income: $1688

Traditional Rental Income: $2520

Airbnb ROI: 3.34%

Traditional ROI: 8.66%

275 Osborn Hill Rd

Tuscumbia, AL

1 beds | 1 baths | 1,536 sq.ft.

$169,900

Airbnb cash on cash: 2.69%

Traditional cash on cash: 8.01%

Airbnb Rental Income: $1118

Traditional Rental Income: $1605

Airbnb ROI: 2.69%

Traditional ROI: 8.01%

304 Maple St

Tuscumbia, AL

4 beds | 2 baths | 2,664 sq.ft.

$219,900

Airbnb cash on cash: 3.61%

Traditional cash on cash: 10.39%

Airbnb Rental Income: $1603

Traditional Rental Income: $2559

Airbnb ROI: 3.61%

Traditional ROI: 10.39%

804 Volunteer Dr

Tuscumbia, AL

3 beds | 2 baths | 2,094 sq.ft.

$259,000

Airbnb cash on cash: 3.09%

Traditional cash on cash: 4.66%

Airbnb Rental Income: $1688

Traditional Rental Income: $1601

Airbnb ROI: 3.09%

Traditional ROI: 4.66%

105 Fieldwood Dr

Tuscumbia, AL

4 beds | 2 baths | 2,193 sq.ft.

$479,900

Airbnb cash on cash: 0.95%

Traditional cash on cash: 2.59%

Airbnb Rental Income: $1603

Traditional Rental Income: $1881

Airbnb ROI: 0.95%

Traditional ROI: 2.59%

202 Fame Ave

Tuscumbia, AL

3 beds | 3 baths | 2,282 sq.ft.

$430,000

Airbnb cash on cash: 1.33%

Traditional cash on cash: 4.85%

Airbnb Rental Income: $1688

Traditional Rental Income: $2638

Airbnb ROI: 1.33%

Traditional ROI: 4.85%

608 Eastman Ave

Tuscumbia, AL

3 beds | 3 baths | 2,300 sq.ft.

$339,900

Airbnb cash on cash: 2.21%

Traditional cash on cash: 6.76%

Airbnb Rental Income: $1688

Traditional Rental Income: $2669

Airbnb ROI: 2.21%