Real Estate Investment Properties for Sale in South San Francisco, CA

Looking for investment property in South San Francisco, CA with high ROI ?

Explore a variety of short-term homes & houses in South San Francisco, CA. Invest wisely with VRBO & South San Francisco, CA Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in South San Francisco, CA

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
322 Commercial Avenue South San Francisco, CA This 7,000 sq ft downtown property features an existing 3-bed, 1.5-bath home plus city-app...	3 beds \| 2 baths \| 1,010 sq.ft.	$1,200,000	Airbnb cash on cash: -0.43% Traditional cash on cash: 1.36% Airbnb Rental Income: $2110 Traditional Rental Income: $3565 Airbnb ROI: -0.43% Traditional ROI: 1.36%
247 Rainier Avenue South San Francisco, CA Modern comfort meets timeless charm in this beautifully updated 3-bedroom, 3-bath home wit...	3 beds \| 3 baths \| 1,722 sq.ft.	$1,638,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 1.18% Airbnb Rental Income: $2110 Traditional Rental Income: $4941 Airbnb ROI: -1.04% Traditional ROI: 1.18%
3550 Carter DR 30 South San Francisco, CA Welcome to this 2 story, townhome style condo offering 3 bedrooms, 2 bathrooms and spannin...	3 beds \| 2 baths \| 1,520 sq.ft.	$648,000	Airbnb cash on cash: -1.34% Traditional cash on cash: 2.84% Airbnb Rental Income: $2110 Traditional Rental Income: $4098 Airbnb ROI: -1.34% Traditional ROI: 2.84%
141 Gardiner Ave South San Francisco, CA 141 Gardiner Ave, South San Francisco, CA 94080 \| Multi Family	8 beds \| 4 baths \| 4,575 sq.ft.	$1,688,000	Airbnb cash on cash: -0.81% Traditional cash on cash: 2.43% Airbnb Rental Income: $2110 Traditional Rental Income: $6648 Airbnb ROI: -0.81% Traditional ROI: 2.43%
645 Baden Ave #4 South San Francisco, CA 645 Baden Ave #4, South San Francisco, CA 94080 \| Condo/Coop	4 beds \| 3 baths \| 1,611 sq.ft.	$1,298,000	Airbnb cash on cash: -0.66% Traditional cash on cash: 0.86% Airbnb Rental Income: $2531 Traditional Rental Income: $3758 Airbnb ROI: -0.66% Traditional ROI: 0.86%
210 7th Ln South San Francisco, CA 210 7th Ln, South San Francisco, CA 94080 \| Single Family Residential	5 beds \| 2 baths \| 1,200 sq.ft.	$1,298,000	Airbnb cash on cash: -0.02% Traditional cash on cash: 1.18% Airbnb Rental Income: $2852 Traditional Rental Income: $3638 Airbnb ROI: -0.02% Traditional ROI: 1.18%
346 Del Monte Ave South San Francisco, CA 346 Del Monte Ave, South San Francisco, CA 94080 \| Single Family Residential	4 beds \| 3 baths \| 2,116 sq.ft.	$1,495,000	Airbnb cash on cash: -0.44% Traditional cash on cash: 1.67% Airbnb Rental Income: $2531 Traditional Rental Income: $4854 Airbnb ROI: -0.44% Traditional ROI: 1.67%
2210 Gellert Blvd #5305 South San Francisco, CA 2210 Gellert Blvd #5305, South San Francisco, CA 94080 \| Condo/Coop	3 beds \| 2 baths \| 1,200 sq.ft.	$892,900	Airbnb cash on cash: -0.89% Traditional cash on cash: 0.96% Airbnb Rental Income: $2110 Traditional Rental Income: $3110 Airbnb ROI: -0.89% Traditional ROI: 0.96%
553 Diamond Ave South San Francisco, CA 553 Diamond Ave, South San Francisco, CA 94080 \| Single Family Residential	4 beds \| 3 baths \| 2,004 sq.ft.	$1,638,000	Airbnb cash on cash: -0.55% Traditional cash on cash: 1.35% Airbnb Rental Income: $2531 Traditional Rental Income: $4810 Airbnb ROI: -0.55% Traditional ROI: 1.35%
725 Palm Ave South San Francisco, CA 725 Palm Ave, South San Francisco, CA 94080 \| Single Family Residential	3 beds \| 2 baths \| 1,210 sq.ft.	$1,288,000	Airbnb cash on cash: -0.52% Traditional cash on cash: 1.11% Airbnb Rental Income: $2110 Traditional Rental Income: $3524 Airbnb ROI: -0.52% Traditional ROI: 1.11%
413 Ferndale AVE South San Francisco, CA Welcome to 413 Ferndale Ave, located in South San Franciscos charming Sunshine Gardens nei...	3 beds \| 1 baths \| 1,070 sq.ft.	$999,888	Airbnb cash on cash: -0.17% Traditional cash on cash: 1.88% Airbnb Rental Income: $2110 Traditional Rental Income: $3478 Airbnb ROI: -0.17% Traditional ROI: 1.88%

Real Estate investment in South-san-francisco, CA

There are 13 properties for sale in the city of South San Francisco . The median list price in South San Francisco is $1,288,000 and the average price per square foot is $769. In December 2025, the average monthly cash on cash return in South San Francisco is 2.00%. The average monthly rental income in South San Francisco is $3,730.

South-san-francisco, CA Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 13 investment properties available for sale in South-san-francisco.

In 2025, the best neighborhood to buy investment property is South San Francisco.

The ROI for Short-Term is higher than the Long-Term in South-san-francisco with average rental income of $2,110.

Your search for investment property begins and ends here

Investment Property for Sale in South San Francisco, CA

322 Commercial Avenue

South San Francisco, CA

3 beds | 2 baths | 1,010 sq.ft.

$1,200,000

Airbnb cash on cash: -0.43%

Traditional cash on cash: 1.36%

Airbnb Rental Income: $2110

Traditional Rental Income: $3565

Airbnb ROI: -0.43%

Traditional ROI: 1.36%

247 Rainier Avenue

South San Francisco, CA

3 beds | 3 baths | 1,722 sq.ft.

$1,638,000

Airbnb cash on cash: -1.04%

Traditional cash on cash: 1.18%

Airbnb Rental Income: $2110

Traditional Rental Income: $4941

Airbnb ROI: -1.04%

Traditional ROI: 1.18%

3550 Carter DR 30

South San Francisco, CA

3 beds | 2 baths | 1,520 sq.ft.

$648,000

Airbnb cash on cash: -1.34%

Traditional cash on cash: 2.84%

Airbnb Rental Income: $2110

Traditional Rental Income: $4098

Airbnb ROI: -1.34%

Traditional ROI: 2.84%

141 Gardiner Ave

South San Francisco, CA

8 beds | 4 baths | 4,575 sq.ft.

$1,688,000

Airbnb cash on cash: -0.81%

Traditional cash on cash: 2.43%

Airbnb Rental Income: $2110

Traditional Rental Income: $6648

Airbnb ROI: -0.81%

Traditional ROI: 2.43%

645 Baden Ave #4

South San Francisco, CA

4 beds | 3 baths | 1,611 sq.ft.

$1,298,000

Airbnb cash on cash: -0.66%

Traditional cash on cash: 0.86%

Airbnb Rental Income: $2531

Traditional Rental Income: $3758

Airbnb ROI: -0.66%

Traditional ROI: 0.86%

210 7th Ln

South San Francisco, CA

5 beds | 2 baths | 1,200 sq.ft.

$1,298,000

Airbnb cash on cash: -0.02%

Traditional cash on cash: 1.18%

Airbnb Rental Income: $2852

Traditional Rental Income: $3638

Airbnb ROI: -0.02%

Traditional ROI: 1.18%

346 Del Monte Ave

South San Francisco, CA

4 beds | 3 baths | 2,116 sq.ft.

$1,495,000

Airbnb cash on cash: -0.44%

Traditional cash on cash: 1.67%

Airbnb Rental Income: $2531

Traditional Rental Income: $4854

Airbnb ROI: -0.44%

Traditional ROI: 1.67%

2210 Gellert Blvd #5305

South San Francisco, CA

3 beds | 2 baths | 1,200 sq.ft.

$892,900

Airbnb cash on cash: -0.89%

Traditional cash on cash: 0.96%

Airbnb Rental Income: $2110

Traditional Rental Income: $3110

Airbnb ROI: -0.89%