Real Estate Investment Properties for Sale in South San Francisco, CA

Looking for investment property in South San Francisco, CA with high ROI ?

Explore a variety of short-term homes & houses in South San Francisco, CA. Invest wisely with VRBO & South San Francisco, CA Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in South San Francisco, CA

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
322 Commercial Avenue South San Francisco, CA This 7,000 sq ft downtown property features an existing 3-bed, 1.5-bath home plus city-app...	3 beds \| 2 baths \| 1,010 sq.ft.	$1,200,000	Airbnb cash on cash: -0.43% Traditional cash on cash: 1.36% Airbnb Rental Income: $2110 Traditional Rental Income: $3565 Airbnb ROI: -0.43% Traditional ROI: 1.36%
247 Rainier Avenue South San Francisco, CA Modern comfort meets timeless charm in this beautifully updated 3-bedroom, 3-bath home wit...	3 beds \| 3 baths \| 1,722 sq.ft.	$1,638,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 1.18% Airbnb Rental Income: $2110 Traditional Rental Income: $4941 Airbnb ROI: -1.04% Traditional ROI: 1.18%
58 Arlington DR South San Francisco, CA Welcome to 58 Arlington Drive, a beautifully updated 3-bedroom, 1-bath home in South San F...	3 beds \| 1 baths \| 990 sq.ft.	$1,098,000	Airbnb cash on cash: 0.29% Traditional cash on cash: 1.99% Airbnb Rental Income: $2110 Traditional Rental Income: $3309 Airbnb ROI: 0.29% Traditional ROI: 1.99%
3550 Carter DR 30 South San Francisco, CA Welcome to this 2 story, townhome style condo offering 3 bedrooms, 2 bathrooms and spannin...	3 beds \| 2 baths \| 1,520 sq.ft.	$648,000	Airbnb cash on cash: -1.34% Traditional cash on cash: 2.84% Airbnb Rental Income: $2110 Traditional Rental Income: $4098 Airbnb ROI: -1.34% Traditional ROI: 2.84%
141 Gardiner Ave South San Francisco, CA 141 Gardiner Ave, South San Francisco, CA 94080 \| Multi Family	8 beds \| 4 baths \| 4,575 sq.ft.	$1,688,000	Airbnb cash on cash: -0.81% Traditional cash on cash: 2.43% Airbnb Rental Income: $2110 Traditional Rental Income: $6648 Airbnb ROI: -0.81% Traditional ROI: 2.43%
645 Baden Ave #4 South San Francisco, CA 645 Baden Ave #4, South San Francisco, CA 94080 \| Condo/Coop	4 beds \| 3 baths \| 1,611 sq.ft.	$1,298,000	Airbnb cash on cash: -0.66% Traditional cash on cash: 0.86% Airbnb Rental Income: $2531 Traditional Rental Income: $3758 Airbnb ROI: -0.66% Traditional ROI: 0.86%
210 7th Ln South San Francisco, CA 210 7th Ln, South San Francisco, CA 94080 \| Single Family Residential	5 beds \| 2 baths \| 1,200 sq.ft.	$1,398,000	Airbnb cash on cash: -0.14% Traditional cash on cash: 0.97% Airbnb Rental Income: $2852 Traditional Rental Income: $3638 Airbnb ROI: -0.14% Traditional ROI: 0.97%
1400 El Camino Real 125 South San Francisco, CA Welcome to 1400 El Camino Real #125 a spacious, light-filled, beautifully remodeled 2 bed...	2 beds \| 2 baths \| 1,257 sq.ft.	$799,000	Airbnb cash on cash: -0.71% Traditional cash on cash: 1.95% Airbnb Rental Income: $2094 Traditional Rental Income: $3533 Airbnb ROI: -0.71% Traditional ROI: 1.95%
346 Del Monte Ave South San Francisco, CA 346 Del Monte Ave, South San Francisco, CA 94080 \| Single Family Residential	4 beds \| 3 baths \| 2,116 sq.ft.	$1,495,000	Airbnb cash on cash: -0.44% Traditional cash on cash: 1.67% Airbnb Rental Income: $2531 Traditional Rental Income: $4854 Airbnb ROI: -0.44% Traditional ROI: 1.67%
532 Theresa Dr South San Francisco, CA 532 Theresa Dr, South San Francisco, CA 94080 \| Single Family Residential	3 beds \| 2 baths \| 1,140 sq.ft.	$1,250,000	Airbnb cash on cash: -0.48% Traditional cash on cash: 1.15% Airbnb Rental Income: $2110 Traditional Rental Income: $3465 Airbnb ROI: -0.48% Traditional ROI: 1.15%
2210 Gellert Blvd #5305 South San Francisco, CA 2210 Gellert Blvd #5305, South San Francisco, CA 94080 \| Condo/Coop	3 beds \| 2 baths \| 1,200 sq.ft.	$895,900	Airbnb cash on cash: -0.89% Traditional cash on cash: 0.95% Airbnb Rental Income: $2110 Traditional Rental Income: $3110 Airbnb ROI: -0.89% Traditional ROI: 0.95%
700 Southwood Drive South San Francisco, CA Welcome to 700 Southwood Drive Located in the highly desirable Southwood neighborhood, th...	3 beds \| 1 baths \| 1,010 sq.ft.	$1,048,888	Airbnb cash on cash: -0.24% Traditional cash on cash: 1.75% Airbnb Rental Income: $2110 Traditional Rental Income: $3509 Airbnb ROI: -0.24% Traditional ROI: 1.75%
553 Diamond Ave South San Francisco, CA 553 Diamond Ave, South San Francisco, CA 94080 \| Single Family Residential	4 beds \| 3 baths \| 2,004 sq.ft.	$1,648,000	Airbnb cash on cash: -0.56% Traditional cash on cash: 1.33% Airbnb Rental Income: $2531 Traditional Rental Income: $4810 Airbnb ROI: -0.56% Traditional ROI: 1.33%
276 Sequoia Ave South San Francisco, CA Come see this we maintained home in the Sunshine Gardens neighborhood, close to schools, f...	3 beds \| 2 baths \| 1,350 sq.ft.	$1,025,000	Airbnb cash on cash: 0.39% Traditional cash on cash: 2.88% Airbnb Rental Income: $2110 Traditional Rental Income: $3944 Airbnb ROI: 0.39% Traditional ROI: 2.88%
3878 Radburn Dr South San Francisco, CA 3878 Radburn Dr, South San Francisco, CA 94080 \| Townhouse	2 beds \| 1 baths \| 858 sq.ft.	$719,888	Airbnb cash on cash: -0.08% Traditional cash on cash: 1.29% Airbnb Rental Income: $2094 Traditional Rental Income: $2481 Airbnb ROI: -0.08% Traditional ROI: 1.29%
1 Mandalay Pl #1201 South San Francisco, CA 1 Mandalay Pl #1201, South San Francisco, CA 94080 \| Condo/Coop	2 beds \| 2 baths \| 1,246 sq.ft.	$999,000	Airbnb cash on cash: -1.07% Traditional cash on cash: 1.1% Airbnb Rental Income: $2094 Traditional Rental Income: $3576 Airbnb ROI: -1.07% Traditional ROI: 1.1%
725 Palm Ave South San Francisco, CA 725 Palm Ave, South San Francisco, CA 94080 \| Single Family Residential	3 beds \| 2 baths \| 1,210 sq.ft.	$1,288,000	Airbnb cash on cash: -0.52% Traditional cash on cash: 1.11% Airbnb Rental Income: $2110 Traditional Rental Income: $3524 Airbnb ROI: -0.52% Traditional ROI: 1.11%
321 Southcliff Ave South San Francisco, CA 321 Southcliff Ave, South San Francisco, CA 94080 \| Single Family Residential	3 beds \| 2 baths \| 1,330 sq.ft.	$1,169,800	Airbnb cash on cash: -0.4% Traditional cash on cash: 1.6% Airbnb Rental Income: $2110 Traditional Rental Income: $3744 Airbnb ROI: -0.4% Traditional ROI: 1.6%

Real Estate investment in South-san-francisco, CA

There are 19 properties for sale in the city of South San Francisco . The median list price in South San Francisco is $1,169,800 and the average price per square foot is $776. In December 2025, the average monthly cash on cash return in South San Francisco is 2.00%. The average monthly rental income in South San Francisco is $3,638.

South-san-francisco, CA Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 19 investment properties available for sale in South-san-francisco.

In 2025, the best neighborhood to buy investment property is South San Francisco.

The ROI for Short-Term is higher than the Long-Term in South-san-francisco with average rental income of $2,110.

Your search for investment property begins and ends here

Investment Property for Sale in South San Francisco, CA

322 Commercial Avenue

South San Francisco, CA

3 beds | 2 baths | 1,010 sq.ft.

$1,200,000

Airbnb cash on cash: -0.43%

Traditional cash on cash: 1.36%

Airbnb Rental Income: $2110

Traditional Rental Income: $3565

Airbnb ROI: -0.43%

Traditional ROI: 1.36%

247 Rainier Avenue

South San Francisco, CA

3 beds | 3 baths | 1,722 sq.ft.

$1,638,000

Airbnb cash on cash: -1.04%

Traditional cash on cash: 1.18%

Airbnb Rental Income: $2110

Traditional Rental Income: $4941

Airbnb ROI: -1.04%

Traditional ROI: 1.18%

58 Arlington DR

South San Francisco, CA

3 beds | 1 baths | 990 sq.ft.

$1,098,000

Airbnb cash on cash: 0.29%

Traditional cash on cash: 1.99%

Airbnb Rental Income: $2110

Traditional Rental Income: $3309

Airbnb ROI: 0.29%

Traditional ROI: 1.99%

3550 Carter DR 30

South San Francisco, CA

3 beds | 2 baths | 1,520 sq.ft.

$648,000

Airbnb cash on cash: -1.34%

Traditional cash on cash: 2.84%

Airbnb Rental Income: $2110

Traditional Rental Income: $4098

Airbnb ROI: -1.34%

Traditional ROI: 2.84%

141 Gardiner Ave

South San Francisco, CA

8 beds | 4 baths | 4,575 sq.ft.

$1,688,000

Airbnb cash on cash: -0.81%

Traditional cash on cash: 2.43%

Airbnb Rental Income: $2110

Traditional Rental Income: $6648

Airbnb ROI: -0.81%

Traditional ROI: 2.43%

645 Baden Ave #4

South San Francisco, CA

4 beds | 3 baths | 1,611 sq.ft.

$1,298,000

Airbnb cash on cash: -0.66%

Traditional cash on cash: 0.86%

Airbnb Rental Income: $2531

Traditional Rental Income: $3758

Airbnb ROI: -0.66%

Traditional ROI: 0.86%

210 7th Ln

South San Francisco, CA

5 beds | 2 baths | 1,200 sq.ft.

$1,398,000

Airbnb cash on cash: -0.14%

Traditional cash on cash: 0.97%

Airbnb Rental Income: $2852

Traditional Rental Income: $3638

Airbnb ROI: -0.14%

Traditional ROI: 0.97%

1400 El Camino Real 125

South San Francisco, CA

2 beds | 2 baths | 1,257 sq.ft.

$799,000

Airbnb cash on cash: -0.71%

Traditional cash on cash: 1.95%

Airbnb Rental Income: $2094

Traditional Rental Income: $3533

Airbnb ROI: -0.71%