Real Estate Investment Properties for Sale in Mesa, CO

Looking for investment property in Mesa, CO with high ROI ?

Explore a variety of short-term homes & houses in Mesa, CO. Invest wisely with VRBO & Mesa, CO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Mesa, CO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
10479 50 Road Mesa, CO WATER WATER WATER- Welcome to your dream ranch! Nestled on the western slope of Colorado, ...	3 beds \| 2 baths \| 2,560 sq.ft.	$819,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.47% Airbnb Rental Income: $null Traditional Rental Income: $2066 Airbnb ROI: N/A Traditional ROI: 1.47%
49594 KE Road Mesa, CO Quality throughout this custom-built house on 75 acres with spectacular views in all direc...	3 beds \| 3 baths \| 2,514 sq.ft.	$1,595,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.8% Airbnb Rental Income: $null Traditional Rental Income: $2848 Airbnb ROI: N/A Traditional ROI: 0.8%
53315 Bull Basin Road Mesa, CO Colorado acreage with a luxury, fully furnished home offering breathtaking, on-top-of-the-...	3 beds \| 4 baths \| 2,242 sq.ft.	$749,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.65% Airbnb Rental Income: $null Traditional Rental Income: $2148 Airbnb ROI: N/A Traditional ROI: 1.65%
49067 KE Road Mesa, CO Great residential opportunity with spacious open floor living space, large open kitchen/is...	2 beds \| 2 baths \| 2,236 sq.ft.	$419,000	Airbnb cash on cash: 2.9% Traditional cash on cash: 3.66% Airbnb Rental Income: $2259 Traditional Rental Income: $1993 Airbnb ROI: 2.9% Traditional ROI: 3.66%
11055 Highway 65 Mesa, CO Property currently used as a residence, with a two bedroom, one bathroom unit in the bath,...	2 beds \| 1 baths \| 2,032 sq.ft.	$379,000	Airbnb cash on cash: 3.19% Traditional cash on cash: 3.9% Airbnb Rental Income: $2259 Traditional Rental Income: $1947 Airbnb ROI: 3.19% Traditional ROI: 3.9%
15078 45 1/2 Road Mesa, CO Looking for space, views and quality? Here it is. Located just 30 mins from Grand Junction...	3 beds \| 2 baths \| 1,440 sq.ft.	$599,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.57% Airbnb Rental Income: $null Traditional Rental Income: $2179 Airbnb ROI: N/A Traditional ROI: 2.57%
48751 Cool Creek Drive Mesa, CO Experience modern comfort and mountain living in this 2018-built, energy-efficient home lo...	2 beds \| 1 baths \| 1,665 sq.ft.	$595,000	Airbnb cash on cash: 1.45% Traditional cash on cash: 1.75% Airbnb Rental Income: $2259 Traditional Rental Income: $1860 Airbnb ROI: 1.45% Traditional ROI: 1.75%
12471 54 7/10 (2 Parcels) Rd Mesa, CO 12471 54 7/10 (2 Parcels) Rd, Mesa, CO 81643 \| Single Family Residential	4 beds \| 3 baths \| 2,429 sq.ft.	$1,800,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.2% Airbnb Rental Income: $null Traditional Rental Income: $2938 Airbnb ROI: N/A Traditional ROI: 0.2%
420 Powder Ridge Cir Mesa, CO 420 Powder Ridge Cir, Mesa, CO 81643 \| Other	N/A beds \| N/A baths \| N/A	$107,500	Airbnb cash on cash: N/A Traditional cash on cash: 5.01% Airbnb Rental Income: $null Traditional Rental Income: $788 Airbnb ROI: N/A Traditional ROI: 5.01%
(Parcel 6) TBD Highway 65 Mesa, CO (Parcel 6) TBD Highway 65, Mesa, CO 81643 \| Other	N/A beds \| N/A baths \| N/A	$425,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.24% Airbnb Rental Income: $null Traditional Rental Income: $788 Airbnb ROI: N/A Traditional ROI: 0.24%
48933 Gaia Dr Mesa, CO 48933 Gaia Dr, Mesa, CO 81643 \| Other	N/A beds \| N/A baths \| N/A	$156,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.63% Airbnb Rental Income: $null Traditional Rental Income: $887 Airbnb ROI: N/A Traditional ROI: 3.63%
(Parcel 8) TBD Highway 65 Mesa, CO (Parcel 8) TBD Highway 65, Mesa, CO 81643 \| Other	N/A beds \| N/A baths \| N/A	$395,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.37% Airbnb Rental Income: $null Traditional Rental Income: $788 Airbnb ROI: N/A Traditional ROI: 0.37%
(Parcel 7) TBD Highway 65 Mesa, CO (Parcel 7) TBD Highway 65, Mesa, CO 81643 \| Other	N/A beds \| N/A baths \| N/A	$395,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.64% Airbnb Rental Income: $null Traditional Rental Income: $887 Airbnb ROI: N/A Traditional ROI: 0.64%
48989 Gaia Dr Mesa, CO 48989 Gaia Dr, Mesa, CO 81643 \| Other	N/A beds \| N/A baths \| N/A	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.01% Airbnb Rental Income: $null Traditional Rental Income: $788 Airbnb ROI: N/A Traditional ROI: 2.01%

Real Estate investment in Mesa, CO

There are 14 properties for sale in the city of Mesa . The median list price in Mesa is $475,000 and the average price per square foot is $234. In January 2026, the average monthly cash on cash return in Mesa is 2.00%. The average monthly rental income in Mesa is $1,904.

Mesa, CO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 14 investment properties available for sale in Mesa.

In 2026, the best neighborhood to buy investment property is Mesa.

The ROI for Short-Term is higher than the Long-Term in Mesa with average rental income of $2,259.

Your search for investment property begins and ends here

Investment Property for Sale in Mesa, CO

10479 50 Road

Mesa, CO

3 beds | 2 baths | 2,560 sq.ft.

$819,000

Airbnb cash on cash: N/A

Traditional cash on cash: 1.47%

Airbnb Rental Income: $null

Traditional Rental Income: $2066

Airbnb ROI: N/A

Traditional ROI: 1.47%

49594 KE Road

Mesa, CO

3 beds | 3 baths | 2,514 sq.ft.

$1,595,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.8%

Airbnb Rental Income: $null

Traditional Rental Income: $2848

Airbnb ROI: N/A

Traditional ROI: 0.8%

53315 Bull Basin Road

Mesa, CO

3 beds | 4 baths | 2,242 sq.ft.

$749,000

Airbnb cash on cash: N/A

Traditional cash on cash: 1.65%

Airbnb Rental Income: $null

Traditional Rental Income: $2148

Airbnb ROI: N/A

Traditional ROI: 1.65%

49067 KE Road

Mesa, CO

2 beds | 2 baths | 2,236 sq.ft.

$419,000

Airbnb cash on cash: 2.9%

Traditional cash on cash: 3.66%

Airbnb Rental Income: $2259

Traditional Rental Income: $1993

Airbnb ROI: 2.9%

Traditional ROI: 3.66%

11055 Highway 65

Mesa, CO

2 beds | 1 baths | 2,032 sq.ft.

$379,000

Airbnb cash on cash: 3.19%

Traditional cash on cash: 3.9%

Airbnb Rental Income: $2259

Traditional Rental Income: $1947

Airbnb ROI: 3.19%

Traditional ROI: 3.9%

15078 45 1/2 Road

Mesa, CO

3 beds | 2 baths | 1,440 sq.ft.

$599,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.57%

Airbnb Rental Income: $null

Traditional Rental Income: $2179

Airbnb ROI: N/A

Traditional ROI: 2.57%

48751 Cool Creek Drive

Mesa, CO

2 beds | 1 baths | 1,665 sq.ft.

$595,000

Airbnb cash on cash: 1.45%

Traditional cash on cash: 1.75%

Airbnb Rental Income: $2259

Traditional Rental Income: $1860

Airbnb ROI: 1.45%

Traditional ROI: 1.75%

12471 54 7/10 (2 Parcels) Rd

Mesa, CO

4 beds | 3 baths | 2,429 sq.ft.

$1,800,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.2%

Airbnb Rental Income: $null

Traditional Rental Income: $2938

Airbnb ROI: N/A