Real Estate Investment Properties for Sale in Lower Matecumbe, FL

Looking for investment property in Lower Matecumbe, FL with high ROI ?

Explore a variety of short-term homes & houses in Lower Matecumbe, FL. Invest wisely with VRBO & Lower Matecumbe, FL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Lower Matecumbe, FL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
74450 Overseas Highway Lower Matecumbe, FL Rare Mixed-Use Opportunity with Spectacular Ocean Views in Islamorada MM 74.5. Endless pos...	3 beds \| 2 baths \| 1,980 sq.ft.	$1,680,000	Airbnb cash on cash: -0.91% Traditional cash on cash: 2.07% Airbnb Rental Income: $1324 Traditional Rental Income: $5567 Airbnb ROI: -0.91% Traditional ROI: 2.07%
75071 Overseas Highway Lower Matecumbe, FL Beautifully renovated oceanfront home in Islamorada offering 100 feet of direct ocean fron...	3 beds \| 2 baths \| 1,260 sq.ft.	$3,199,000	Airbnb cash on cash: -1.4% Traditional cash on cash: -0.5% Airbnb Rental Income: $1324 Traditional Rental Income: $3592 Airbnb ROI: -1.4% Traditional ROI: -0.5%
121 Venetian Drive Lower Matecumbe, FL Discover the ultimate waterfront retreat in the heart of Islamorada, in the highly sought ...	3 beds \| 2 baths \| 1,278 sq.ft.	$1,599,000	Airbnb cash on cash: -1.22% Traditional cash on cash: 0.91% Airbnb Rental Income: $1324 Traditional Rental Income: $4080 Airbnb ROI: -1.22% Traditional ROI: 0.91%
75751 Overseas Highway Lower Matecumbe, FL Extraordinary opportunity to own one of the Florida Keys' most spectacular oceanfront resi...	5 beds \| 5 baths \| 3,421 sq.ft.	$11,000,000	Airbnb cash on cash: N/A Traditional cash on cash: -0.92% Airbnb Rental Income: $null Traditional Rental Income: $6231 Airbnb ROI: N/A Traditional ROI: -0.92%
122 Court Contessa Lower Matecumbe, FL 'Turnkey Deepwater Boater's Retreat with Private Beach Access in the Heart of Islamorada' ...	3 beds \| 3 baths \| 2,374 sq.ft.	$2,740,000	Airbnb cash on cash: -1.2% Traditional cash on cash: 0.73% Airbnb Rental Income: $1324 Traditional Rental Income: $5820 Airbnb ROI: -1.2% Traditional ROI: 0.73%
88 W Plaza Del Lago Lower Matecumbe, FL Experience elevated coastal living in this elegant Port Antigua retreat. Thoughtfully desi...	5 beds \| 5 baths \| 4,064 sq.ft.	$4,750,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.23% Airbnb Rental Income: $null Traditional Rental Income: $8030 Airbnb ROI: N/A Traditional ROI: 0.23%
137 Sapodilla Drive Lower Matecumbe, FL Big, beautiful, and exceptionally solid, this waterfront Islamorada residence is perfectly...	5 beds \| 6 baths \| 5,456 sq.ft.	$5,999,999	Airbnb cash on cash: N/A Traditional cash on cash: 0.89% Airbnb Rental Income: $null Traditional Rental Income: $13688 Airbnb ROI: N/A Traditional ROI: 0.89%
110 Gulfview Drive Lower Matecumbe, FL A Keys compound built to enjoy now-grow into the future, or internally convert to a 3,524 ...	7 beds \| 4 baths \| 3,524 sq.ft.	$3,524,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.34% Airbnb Rental Income: $null Traditional Rental Income: $7715 Airbnb ROI: N/A Traditional ROI: 1.34%
101 Madeira Court Lower Matecumbe, FL Welcome to your coastal retreat in the highly sought-after Port Antigua neighborhood--wher...	3 beds \| 3 baths \| 1,947 sq.ft.	$2,890,000	Airbnb cash on cash: -1.19% Traditional cash on cash: 0.47% Airbnb Rental Income: $1324 Traditional Rental Income: $5368 Airbnb ROI: -1.19% Traditional ROI: 0.47%
75710 Overseas Highway #1 Lower Matecumbe, FL Fully furnished turn key townhome in Islamorada at Las Maravillas is available, one of onl...	2 beds \| 2 baths \| 1,124 sq.ft.	$749,999	Airbnb cash on cash: -0.71% Traditional cash on cash: 0.84% Airbnb Rental Income: $1991 Traditional Rental Income: $2548 Airbnb ROI: -0.71% Traditional ROI: 0.84%
74980 Overseas Highway #3 Lower Matecumbe, FL Experience the ultimate Florida Keys lifestyle in this stunning split-level waterfront lof...	5 beds \| 3 baths \| 2,845 sq.ft.	$1,890,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.22% Airbnb Rental Income: $null Traditional Rental Income: $5190 Airbnb ROI: N/A Traditional ROI: 1.22%
75090 Overseas Highway Lower Matecumbe, FL Villa Lago is an Italian-inspired waterfront estate positioned along 220 feet of pristine ...	4 beds \| 6 baths \| 8,194 sq.ft.	$29,000,000	Airbnb cash on cash: -1% Traditional cash on cash: -0.88% Airbnb Rental Income: $8621 Traditional Rental Income: $10426 Airbnb ROI: -1% Traditional ROI: -0.88%
100 Iroquois Drive #5 Lower Matecumbe, FL This waterfront townhome offers 36 feet of dockage and a beautifully renovated interior de...	3 beds \| 3 baths \| 1,710 sq.ft.	$999,999	Airbnb cash on cash: -0.72% Traditional cash on cash: 2.47% Airbnb Rental Income: $1324 Traditional Rental Income: $3888 Airbnb ROI: -0.72% Traditional ROI: 2.47%

Real Estate investment in Lower-matecumbe, FL

There are 15 properties for sale in the city of Lower Matecumbe . The median list price in Lower Matecumbe is $3,044,500 and the average price per square foot is $1,005. In September 2026, the average monthly cash on cash return in Lower Matecumbe is N/A%. The average monthly rental income in Lower Matecumbe is $5,190.

Lower-matecumbe, FL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 15 investment properties available for sale in Lower-matecumbe.

In 2026, the best neighborhood to buy investment property is Lower Matecumbe.

The ROI for Long-Term is higher than the Short-Term in Lower-matecumbe with average rental income of $5,190.

Your search for investment property begins and ends here

Investment Property for Sale in Lower Matecumbe, FL

74450 Overseas Highway

Lower Matecumbe, FL

3 beds | 2 baths | 1,980 sq.ft.

$1,680,000

Airbnb cash on cash: -0.91%

Traditional cash on cash: 2.07%

Airbnb Rental Income: $1324

Traditional Rental Income: $5567

Airbnb ROI: -0.91%

Traditional ROI: 2.07%

75071 Overseas Highway

Lower Matecumbe, FL

3 beds | 2 baths | 1,260 sq.ft.

$3,199,000

Airbnb cash on cash: -1.4%

Traditional cash on cash: -0.5%

Airbnb Rental Income: $1324

Traditional Rental Income: $3592

Airbnb ROI: -1.4%

Traditional ROI: -0.5%

121 Venetian Drive

Lower Matecumbe, FL

3 beds | 2 baths | 1,278 sq.ft.

$1,599,000

Airbnb cash on cash: -1.22%

Traditional cash on cash: 0.91%

Airbnb Rental Income: $1324

Traditional Rental Income: $4080

Airbnb ROI: -1.22%

Traditional ROI: 0.91%

75751 Overseas Highway

Lower Matecumbe, FL

5 beds | 5 baths | 3,421 sq.ft.

$11,000,000

Airbnb cash on cash: N/A

Traditional cash on cash: -0.92%

Airbnb Rental Income: $null

Traditional Rental Income: $6231

Airbnb ROI: N/A

Traditional ROI: -0.92%

122 Court Contessa

Lower Matecumbe, FL

3 beds | 3 baths | 2,374 sq.ft.

$2,740,000

Airbnb cash on cash: -1.2%

Traditional cash on cash: 0.73%

Airbnb Rental Income: $1324

Traditional Rental Income: $5820

Airbnb ROI: -1.2%

Traditional ROI: 0.73%

88 W Plaza Del Lago

Lower Matecumbe, FL

5 beds | 5 baths | 4,064 sq.ft.

$4,750,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.23%

Airbnb Rental Income: $null

Traditional Rental Income: $8030

Airbnb ROI: N/A

Traditional ROI: 0.23%

137 Sapodilla Drive

Lower Matecumbe, FL

5 beds | 6 baths | 5,456 sq.ft.

$5,999,999

Airbnb cash on cash: N/A

Traditional cash on cash: 0.89%

Airbnb Rental Income: $null

Traditional Rental Income: $13688

Airbnb ROI: N/A

Traditional ROI: 0.89%

110 Gulfview Drive

Lower Matecumbe, FL

7 beds | 4 baths | 3,524 sq.ft.

$3,524,000

Airbnb cash on cash: N/A

Traditional cash on cash: 1.34%

Airbnb Rental Income: $null

Traditional Rental Income: $7715

Airbnb ROI: N/A