Real Estate Investment Properties for Sale in Murphysboro, IL

Looking for investment property in Murphysboro, IL with high ROI ?

Explore a variety of short-term homes & houses in Murphysboro, IL. Invest wisely with VRBO & Murphysboro, IL Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Murphysboro, IL

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
6952 W Pleasant Hill Rd Murphysboro, IL Move in ready 4 bedroom home in the country on almost 3 acres with a 40x22 pole building. ...	4 beds \| 1 baths \| 1,440 sq.ft.	$170,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.44% Airbnb Rental Income: $null Traditional Rental Income: $1786 Airbnb ROI: N/A Traditional ROI: 8.44%
2372 Logan St Murphysboro, IL This 4 bedroom, 3 full bath home is private with a serene location. This custom built home...	5 beds \| 3 baths \| 2,737 sq.ft.	$369,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.67% Airbnb Rental Income: $null Traditional Rental Income: $3110 Airbnb ROI: N/A Traditional ROI: 5.67%
2101 Walnut St Murphysboro, IL Welcome to 2101 Walnut Street, a beautifully maintained two-story home full of character a...	3 beds \| 2 baths \| 3,574 sq.ft.	$199,000	Airbnb cash on cash: -1.4% Traditional cash on cash: 10.81% Airbnb Rental Income: $997 Traditional Rental Income: $2947 Airbnb ROI: -1.4% Traditional ROI: 10.81%
267 Brian Ave Murphysboro, IL 267 Brian Ave, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 4 baths \| 5,543 sq.ft.	$695,000	Airbnb cash on cash: -2.41% Traditional cash on cash: 0.77% Airbnb Rental Income: $997 Traditional Rental Income: $2704 Airbnb ROI: -2.41% Traditional ROI: 0.77%
2479 New Era Rd Murphysboro, IL 2479 New Era Rd, Murphysboro, IL 62966 \| Single Family Residential	5 beds \| 5 baths \| 7,056 sq.ft.	$870,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.22% Airbnb Rental Income: $null Traditional Rental Income: $6152 Airbnb ROI: N/A Traditional ROI: 4.22%
15 Oakwood Ln Murphysboro, IL 15 Oakwood Ln, Murphysboro, IL 62966 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$75,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.75% Airbnb Rental Income: $null Traditional Rental Income: $1050 Airbnb ROI: N/A Traditional ROI: 9.75%
156 Hanover Ln Murphysboro, IL 156 Hanover Ln, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 1,828 sq.ft.	$329,000	Airbnb cash on cash: -1.49% Traditional cash on cash: 2.94% Airbnb Rental Income: $997 Traditional Rental Income: $2013 Airbnb ROI: -1.49% Traditional ROI: 2.94%
29 Ava Rd Murphysboro, IL 29 Ava Rd, Murphysboro, IL 62966 \| Single Family Residential	5 beds \| N/A baths \| 2,400 sq.ft.	$150,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.62% Airbnb Rental Income: $null Traditional Rental Income: $1792 Airbnb ROI: N/A Traditional ROI: 8.62%
0000 Highway 13 Murphysboro, IL 0000 Highway 13, Murphysboro, IL 62966 \| Other	N/A beds \| N/A baths \| N/A	$154,800	Airbnb cash on cash: N/A Traditional cash on cash: 1.57% Airbnb Rental Income: $null Traditional Rental Income: $802 Airbnb ROI: N/A Traditional ROI: 1.57%
8193 Old Highway 13 Hwy Murphysboro, IL 8193 Old Highway 13 Hwy, Murphysboro, IL 62966 \| Single Family Residential	4 beds \| 2 baths \| 1,800 sq.ft.	$347,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.01% Airbnb Rental Income: $null Traditional Rental Income: $2136 Airbnb ROI: N/A Traditional ROI: 3.01%
1914 Clarke St Murphysboro, IL 1914 Clarke St, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 1,177 sq.ft.	$150,000	Airbnb cash on cash: 0.61% Traditional cash on cash: 8.53% Airbnb Rental Income: $997 Traditional Rental Income: $1779 Airbnb ROI: 0.61% Traditional ROI: 8.53%
111 Devan Drive Murphysboro, IL This rare, income-producing mobile home park sits on 8.8 acres of versatile land with plen...	N/A beds \| N/A baths \| N/A	$849,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.72% Airbnb Rental Income: $null Traditional Rental Income: $1703 Airbnb ROI: N/A Traditional ROI: 0.72%
1925 Hamilton St Murphysboro, IL 1925 Hamilton St, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 1,248 sq.ft.	$155,000	Airbnb cash on cash: 0.49% Traditional cash on cash: 8.06% Airbnb Rental Income: $997 Traditional Rental Income: $1763 Airbnb ROI: 0.49% Traditional ROI: 8.06%
3 Brock Ln Murphysboro, IL 3 Brock Ln, Murphysboro, IL 62966 \| Single Family Residential	5 beds \| 3 baths \| 3,432 sq.ft.	$415,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.15% Airbnb Rental Income: $null Traditional Rental Income: $2971 Airbnb ROI: N/A Traditional ROI: 4.15%
916 Illinois Ave Murphysboro, IL This is a single family home. This home is located at 916 Illinois Ave, Murphysboro, IL 62...	4 beds \| 2 baths \| 2,672 sq.ft.	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.26% Airbnb Rental Income: $null Traditional Rental Income: $931 Airbnb ROI: N/A Traditional ROI: 2.26%
2368 Watt Hill Rd Murphysboro, IL 2368 Watt Hill Rd, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 2,800 sq.ft.	$695,000	Airbnb cash on cash: -2.41% Traditional cash on cash: -0.06% Airbnb Rental Income: $997 Traditional Rental Income: $2165 Airbnb ROI: -2.41% Traditional ROI: -0.06%
22 Old Brick Rd Murphysboro, IL This property has 3 bedrooms and 2 bathrooms in the main level, with a half bath in the ba...	3 beds \| 2 baths \| 1,422 sq.ft.	$197,500	Airbnb cash on cash: 1.5% Traditional cash on cash: 9.32% Airbnb Rental Income: $997 Traditional Rental Income: $2109 Airbnb ROI: 1.5% Traditional ROI: 9.32%
18 Buena Vista Dr Murphysboro, IL 18 Buena Vista Dr, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 3,437 sq.ft.	$244,500	Airbnb cash on cash: -0.86% Traditional cash on cash: 4.77% Airbnb Rental Income: $997 Traditional Rental Income: $1942 Airbnb ROI: -0.86% Traditional ROI: 4.77%
1324 Turner St Murphysboro, IL 1324 Turner St, Murphysboro, IL 62966 \| Single Family Residential	2 beds \| 1 baths \| 994 sq.ft.	$104,900	Airbnb cash on cash: 0.71% Traditional cash on cash: 9.83% Airbnb Rental Income: $815 Traditional Rental Income: $1418 Airbnb ROI: 0.71% Traditional ROI: 9.83%
6414 Ava Rd Murphysboro, IL	4 beds \| 4 baths \| 3,468 sq.ft.	$1,295,000	Airbnb cash on cash: N/A Traditional cash on cash: -0.59% Airbnb Rental Income: $null Traditional Rental Income: $3308 Airbnb ROI: N/A Traditional ROI: -0.59%
1612 Shomaker Dr Murphysboro, IL 1612 Shomaker Dr, Murphysboro, IL 62966 \| Single Family Residential	5 beds \| 3 baths \| 2,566 sq.ft.	$239,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.2% Airbnb Rental Income: $null Traditional Rental Income: $2922 Airbnb ROI: N/A Traditional ROI: 9.2%
00 Shoemaker Dr Murphysboro, IL 00 Shoemaker Dr, Murphysboro, IL 62966 \| Other	N/A beds \| N/A baths \| N/A	$125,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.38% Airbnb Rental Income: $null Traditional Rental Income: $885 Airbnb ROI: N/A Traditional ROI: 3.38%
1302 &1306 Walnut St Murphysboro, IL 1302 &1306 Walnut St, Murphysboro, IL 62966 \| Single Family Residential	4 beds \| N/A baths \| 5,996 sq.ft.	$350,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.71% Airbnb Rental Income: $null Traditional Rental Income: $2050 Airbnb ROI: N/A Traditional ROI: 2.71%
1232 Dallas Rd Murphysboro, IL 1232 Dallas Rd, Murphysboro, IL 62966 \| Single Family Residential	4 beds \| 1 baths \| 1,210 sq.ft.	$119,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.46% Airbnb Rental Income: $null Traditional Rental Income: $1777 Airbnb ROI: N/A Traditional ROI: 11.46%
15 Pine Ln Murphysboro, IL 15 Pine Ln, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 1,500 sq.ft.	$209,900	Airbnb cash on cash: -0.47% Traditional cash on cash: 6.42% Airbnb Rental Income: $997 Traditional Rental Income: $2014 Airbnb ROI: -0.47% Traditional ROI: 6.42%
67 Scouts Rd Murphysboro, IL 67 Scouts Rd, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 1 baths \| 1,024 sq.ft.	$149,000	Airbnb cash on cash: 0.63% Traditional cash on cash: 7.09% Airbnb Rental Income: $997 Traditional Rental Income: $1562 Airbnb ROI: 0.63% Traditional ROI: 7.09%
215 S 20th St Murphysboro, IL 215 S 20th St, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 1 baths \| 1,756 sq.ft.	$179,900	Airbnb cash on cash: -0.02% Traditional cash on cash: 6.31% Airbnb Rental Income: $997 Traditional Rental Income: $1725 Airbnb ROI: -0.02% Traditional ROI: 6.31%
107 Jenkins Rd Murphysboro, IL 107 Jenkins Rd, Murphysboro, IL 62966 \| Single Family Residential	4 beds \| 3 baths \| 4,596 sq.ft.	$369,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.58% Airbnb Rental Income: $null Traditional Rental Income: $2809 Airbnb ROI: N/A Traditional ROI: 4.58%
804 N 22nd St Murphysboro, IL 804 N 22nd St, Murphysboro, IL 62966 \| Single Family Residential	4 beds \| 1 baths \| 1,739 sq.ft.	$329,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.21% Airbnb Rental Income: $null Traditional Rental Income: $1783 Airbnb ROI: N/A Traditional ROI: 2.21%
928 N 7th St Murphysboro, IL	2 beds \| 1 baths \| 840 sq.ft.	$89,500	Airbnb cash on cash: 1.36% Traditional cash on cash: 11.17% Airbnb Rental Income: $815 Traditional Rental Income: $1349 Airbnb ROI: 1.36% Traditional ROI: 11.17%
89 Dogwood Rd Murphysboro, IL 89 Dogwood Rd, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 1,680 sq.ft.	$219,000	Airbnb cash on cash: -0.58% Traditional cash on cash: 6.61% Airbnb Rental Income: $997 Traditional Rental Income: $2133 Airbnb ROI: -0.58% Traditional ROI: 6.61%
1457 W Lake Dr Murphysboro, IL 1457 W Lake Dr, Murphysboro, IL 62966 \| Multi Family	8 beds \| 4 baths \| N/A	$235,000	Airbnb cash on cash: -0.77% Traditional cash on cash: 10.97% Airbnb Rental Income: $997 Traditional Rental Income: $3250 Airbnb ROI: -0.77% Traditional ROI: 10.97%
68 Lost Ranch Rd Murphysboro, IL 68 Lost Ranch Rd, Murphysboro, IL 62966 \| Other	N/A beds \| N/A baths \| N/A	$140,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.68% Airbnb Rental Income: $null Traditional Rental Income: $885 Airbnb ROI: N/A Traditional ROI: 2.68%
3419 W Grange Hall Rd Murphysboro, IL 3419 W Grange Hall Rd, Murphysboro, IL 62966 \| Single Family Residential	3 beds \| 2 baths \| 1,864 sq.ft.	$249,000	Airbnb cash on cash: -0.9% Traditional cash on cash: 5.63% Airbnb Rental Income: $997 Traditional Rental Income: $2179 Airbnb ROI: -0.9% Traditional ROI: 5.63%

Real Estate investment in Murphysboro, IL

There are 35 properties for sale in the city of Murphysboro . The median list price in Murphysboro is $94,943 and the average price per square foot is $46. In August 2026, the average monthly cash on cash return in Murphysboro is 10.00%. The average monthly rental income in Murphysboro is $1,723.

Murphysboro, IL Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 35 investment properties available for sale in Murphysboro.

In 2026, the best neighborhood to buy investment property is Murphysboro.

The ROI for Short-Term is higher than the Long-Term in Murphysboro with average rental income of $997.

Your search for investment property begins and ends here

Investment Property for Sale in Murphysboro, IL

6952 W Pleasant Hill Rd

Murphysboro, IL

4 beds | 1 baths | 1,440 sq.ft.

$170,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.44%

Airbnb Rental Income: $null

Traditional Rental Income: $1786

Airbnb ROI: N/A

Traditional ROI: 8.44%

2372 Logan St

Murphysboro, IL

5 beds | 3 baths | 2,737 sq.ft.

$369,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.67%

Airbnb Rental Income: $null

Traditional Rental Income: $3110

Airbnb ROI: N/A

Traditional ROI: 5.67%

2101 Walnut St

Murphysboro, IL

3 beds | 2 baths | 3,574 sq.ft.

$199,000

Airbnb cash on cash: -1.4%

Traditional cash on cash: 10.81%

Airbnb Rental Income: $997

Traditional Rental Income: $2947

Airbnb ROI: -1.4%

Traditional ROI: 10.81%

267 Brian Ave

Murphysboro, IL

3 beds | 4 baths | 5,543 sq.ft.

$695,000

Airbnb cash on cash: -2.41%

Traditional cash on cash: 0.77%

Airbnb Rental Income: $997

Traditional Rental Income: $2704

Airbnb ROI: -2.41%

Traditional ROI: 0.77%

2479 New Era Rd

Murphysboro, IL

5 beds | 5 baths | 7,056 sq.ft.

$870,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.22%

Airbnb Rental Income: $null

Traditional Rental Income: $6152

Airbnb ROI: N/A

Traditional ROI: 4.22%

15 Oakwood Ln

Murphysboro, IL

N/A beds | N/A baths | 0 sq.ft.

$75,000

Airbnb cash on cash: N/A

Traditional cash on cash: 9.75%

Airbnb Rental Income: $null

Traditional Rental Income: $1050

Airbnb ROI: N/A

Traditional ROI: 9.75%

156 Hanover Ln

Murphysboro, IL

3 beds | 2 baths | 1,828 sq.ft.

$329,000

Airbnb cash on cash: -1.49%

Traditional cash on cash: 2.94%

Airbnb Rental Income: $997

Traditional Rental Income: $2013

Airbnb ROI: -1.49%

Traditional ROI: 2.94%

29 Ava Rd

Murphysboro, IL

5 beds | N/A baths | 2,400 sq.ft.

$150,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.62%

Airbnb Rental Income: $null

Traditional Rental Income: $1792

Airbnb ROI: N/A