Real Estate Investment Properties for Sale in Muscatine, IA

Looking for investment property in Muscatine, IA with high ROI ?

Explore a variety of short-term homes & houses in Muscatine, IA. Invest wisely with VRBO & Muscatine, IA Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Muscatine, IA

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
108 Middle Rd Muscatine, IA Charming 3-bedroom, 2-bath home with hardwood floors, butcher block counters, and open she...	3 beds \| 1 baths \| 1,688 sq.ft.	$255,000	Airbnb cash on cash: -0.91% Traditional cash on cash: 5.78% Airbnb Rental Income: $739 Traditional Rental Income: $2037 Airbnb ROI: -0.91% Traditional ROI: 5.78%
1507 Duncan Dr Muscatine, IA This quaint two-story cottage features four bedrooms and three bathrooms, offering over 1,...	4 beds \| 3 baths \| 1,553 sq.ft.	$295,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.33% Airbnb Rental Income: $null Traditional Rental Income: $2283 Airbnb ROI: N/A Traditional ROI: 5.33%
1416 Duncan Dr Muscatine, IA This split-foyer new construction single-family home features 4 bedrooms, 3 bathrooms, and...	4 beds \| 3 baths \| 2,293 sq.ft.	$325,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.87% Airbnb Rental Income: $null Traditional Rental Income: $2360 Airbnb ROI: N/A Traditional ROI: 4.87%
211 EAGLE RIDGE Road Muscatine, IA Beautifully Updated Home Inside and Out! Step into the welcoming foyer and immediately fee...	5 beds \| 3 baths \| 2,544 sq.ft.	$360,000	Airbnb cash on cash: -0.04% Traditional cash on cash: 6.35% Airbnb Rental Income: $1470 Traditional Rental Income: $3197 Airbnb ROI: -0.04% Traditional ROI: 6.35%
3103 Ginkgo Ln Muscatine, IA This split-foyer new construction single-family home features 4 bedrooms, 3 bathrooms, and...	4 beds \| 3 baths \| 2,293 sq.ft.	$319,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.18% Airbnb Rental Income: $null Traditional Rental Income: $2559 Airbnb ROI: N/A Traditional ROI: 7.18%
1421 Duncan Dr Muscatine, IA This newly constructed ranch-style home features a full basement, 4 bedrooms & 3 baths wit...	4 beds \| 3 baths \| 2,205 sq.ft.	$375,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.51% Airbnb Rental Income: $null Traditional Rental Income: $2391 Airbnb ROI: N/A Traditional ROI: 5.51%
1503 Duncan Dr Muscatine, IA This newly constructed ranch-style home features a full basement, 4 bedrooms & 3 baths wit...	4 beds \| 3 baths \| 2,205 sq.ft.	$375,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.51% Airbnb Rental Income: $null Traditional Rental Income: $2391 Airbnb ROI: N/A Traditional ROI: 5.51%
2143 Madison St Muscatine, IA 2143 Madison St, Muscatine, IA 52761 \| Single Family Residential	4 beds \| N/A baths \| 2,898 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.33% Airbnb Rental Income: $null Traditional Rental Income: $1652 Airbnb ROI: N/A Traditional ROI: 8.33%
1708 Schley Ave Muscatine, IA 1708 Schley Ave, Muscatine, IA 52761 \| Single Family Residential	3 beds \| N/A baths \| 1,360 sq.ft.	$172,900	Airbnb cash on cash: -0.51% Traditional cash on cash: 7.85% Airbnb Rental Income: $739 Traditional Rental Income: $1804 Airbnb ROI: -0.51% Traditional ROI: 7.85%
140 Sheridan St Muscatine, IA 140 Sheridan St, Muscatine, IA 52761 \| Single Family Residential	2 beds \| N/A baths \| 1,192 sq.ft.	$119,000	Airbnb cash on cash: 0% Traditional cash on cash: 7.71% Airbnb Rental Income: $687 Traditional Rental Income: $1269 Airbnb ROI: 0% Traditional ROI: 7.71%
2810 Musquota Dr Muscatine, IA 2810 Musquota Dr, Muscatine, IA 52761 \| Single Family Residential	5 beds \| N/A baths \| 3,610 sq.ft.	$340,000	Airbnb cash on cash: 0.4% Traditional cash on cash: 3.52% Airbnb Rental Income: $1470 Traditional Rental Income: $2032 Airbnb ROI: 0.4% Traditional ROI: 3.52%
2310 Forest Pkwy Muscatine, IA 2310 Forest Pkwy, Muscatine, IA 52761 \| Single Family Residential	3 beds \| N/A baths \| 2,688 sq.ft.	$234,900	Airbnb cash on cash: -1.04% Traditional cash on cash: 4.84% Airbnb Rental Income: $739 Traditional Rental Income: $1734 Airbnb ROI: -1.04% Traditional ROI: 4.84%
517 E 6th St Muscatine, IA 517 E 6th St, Muscatine, IA 52761 \| Single Family Residential	3 beds \| N/A baths \| 1,224 sq.ft.	$179,900	Airbnb cash on cash: -0.59% Traditional cash on cash: 5.92% Airbnb Rental Income: $739 Traditional Rental Income: $1541 Airbnb ROI: -0.59% Traditional ROI: 5.92%
615 Mulberry Ave Muscatine, IA 615 Mulberry Ave, Muscatine, IA 52761 \| Single Family Residential	3 beds \| N/A baths \| 1,738 sq.ft.	$189,900	Airbnb cash on cash: -0.69% Traditional cash on cash: 6.71% Airbnb Rental Income: $739 Traditional Rental Income: $1763 Airbnb ROI: -0.69% Traditional ROI: 6.71%

Real Estate investment in Muscatine, IA

There are 68 properties for sale in the city of Muscatine . The median list price in Muscatine is $189,900 and the average price per square foot is $156. In February 2026, the average monthly cash on cash return in Muscatine is 6.00%. The average monthly rental income in Muscatine is $2,160.

Muscatine, IA Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 68 investment properties available for sale in Muscatine.

In 2026, the best neighborhood to buy investment property is Muscatine.

The ROI for Short-Term is higher than the Long-Term in Muscatine with average rental income of $739.

Your search for investment property begins and ends here

Investment Property for Sale in Muscatine, IA

108 Middle Rd

Muscatine, IA

3 beds | 1 baths | 1,688 sq.ft.

$255,000

Airbnb cash on cash: -0.91%

Traditional cash on cash: 5.78%

Airbnb Rental Income: $739

Traditional Rental Income: $2037

Airbnb ROI: -0.91%

Traditional ROI: 5.78%

1507 Duncan Dr

Muscatine, IA

4 beds | 3 baths | 1,553 sq.ft.

$295,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.33%

Airbnb Rental Income: $null

Traditional Rental Income: $2283

Airbnb ROI: N/A

Traditional ROI: 5.33%

1416 Duncan Dr

Muscatine, IA

4 beds | 3 baths | 2,293 sq.ft.

$325,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.87%

Airbnb Rental Income: $null

Traditional Rental Income: $2360

Airbnb ROI: N/A

Traditional ROI: 4.87%

211 EAGLE RIDGE Road

Muscatine, IA

5 beds | 3 baths | 2,544 sq.ft.

$360,000

Airbnb cash on cash: -0.04%

Traditional cash on cash: 6.35%

Airbnb Rental Income: $1470

Traditional Rental Income: $3197

Airbnb ROI: -0.04%

Traditional ROI: 6.35%

3103 Ginkgo Ln

Muscatine, IA

4 beds | 3 baths | 2,293 sq.ft.

$319,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.18%

Airbnb Rental Income: $null

Traditional Rental Income: $2559

Airbnb ROI: N/A

Traditional ROI: 7.18%

1421 Duncan Dr

Muscatine, IA

4 beds | 3 baths | 2,205 sq.ft.

$375,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.51%

Airbnb Rental Income: $null

Traditional Rental Income: $2391

Airbnb ROI: N/A

Traditional ROI: 5.51%

1503 Duncan Dr

Muscatine, IA

4 beds | 3 baths | 2,205 sq.ft.

$375,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.51%

Airbnb Rental Income: $null

Traditional Rental Income: $2391

Airbnb ROI: N/A

Traditional ROI: 5.51%

2143 Madison St

Muscatine, IA

4 beds | N/A baths | 2,898 sq.ft.

$149,900

Airbnb cash on cash: N/A

Traditional cash on cash: 8.33%

Airbnb Rental Income: $null

Traditional Rental Income: $1652

Airbnb ROI: N/A