Real Estate Investment Properties for Sale in Knoxville, MD

Looking for investment property in Knoxville, MD with high ROI ?

Explore a variety of short-term homes & houses in Knoxville, MD. Invest wisely with VRBO & Knoxville, MD Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Knoxville, MD

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
903 ISRAEL CREEK CT KNOXVILLE, MD Set against a backdrop of open skies and rolling views, this custom-built Colonial on over...	4 beds \| 4 baths \| N/A	$759,900	Airbnb cash on cash: 2.71% Traditional cash on cash: 3.07% Airbnb Rental Income: $4120 Traditional Rental Income: $3499 Airbnb ROI: 2.71% Traditional ROI: 3.07%
1411 Jefferson Pike KNOXVILLE, MD This exceptional home situated on over an acre of land in rural Frederick County blends ti...	5 beds \| 4 baths \| 3,400 sq.ft.	$925,000	Airbnb cash on cash: 1.15% Traditional cash on cash: 0.64% Airbnb Rental Income: $3585 Traditional Rental Income: $2342 Airbnb ROI: 1.15% Traditional ROI: 0.64%
608 Jefferson Pike KNOXVILLE, MD Welcome to 608 Jefferson Pike, a truly extraordinary historic estate where timeless elegan...	4 beds \| 2 baths \| 4,058 sq.ft.	$950,000	Airbnb cash on cash: 1.7% Traditional cash on cash: 1.75% Airbnb Rental Income: $4120 Traditional Rental Income: $3286 Airbnb ROI: 1.7% Traditional ROI: 1.75%
724 Jefferson Pike KNOXVILLE, MD This charming ranch-style home in the desirable Knoxville neighborhood offers a perfect bl...	3 beds \| 1 baths \| 1,800 sq.ft.	$390,000	Airbnb cash on cash: 1.22% Traditional cash on cash: 4.41% Airbnb Rental Income: $1678 Traditional Rental Income: $2379 Airbnb ROI: 1.22% Traditional ROI: 4.41%
230 KNOXVILLE Road KNOXVILLE, MD Back to Active! Don't miss this opportunity! Three bedroom, two bath single family home pr...	3 beds \| 2 baths \| 1,496 sq.ft.	$248,000	Airbnb cash on cash: 3.06% Traditional cash on cash: 7.45% Airbnb Rental Income: $1678 Traditional Rental Income: $2237 Airbnb ROI: 3.06% Traditional ROI: 7.45%
Harpers Ferry Rd KNOXVILLE, MD To Be Built Listing By Oliver Homes, Inc. The List Price includes: lot, site cost estimate...	3 beds \| 2 baths \| 1,870 sq.ft.	$577,500	Airbnb cash on cash: 0.84% Traditional cash on cash: 3.15% Airbnb Rental Income: $1678 Traditional Rental Income: $2469 Airbnb ROI: 0.84% Traditional ROI: 3.15%
325 E MOUNTAIN RD KNOXVILLE, MD Nestled on 2.5 picturesque acres with breathtaking South Mountain views, this spacious Vic...	4 beds \| 3 baths \| N/A	$585,000	Airbnb cash on cash: 3.64% Traditional cash on cash: 3.37% Airbnb Rental Income: $4120 Traditional Rental Income: $3099 Airbnb ROI: 3.64% Traditional ROI: 3.37%
18854 SANDY HOOK Road KNOXVILLE, MD Discover this charming, move-in-ready 1918 single-family home offering 2,835 square feet o...	3 beds \| 2 baths \| 2,835 sq.ft.	$370,000	Airbnb cash on cash: 1.52% Traditional cash on cash: 5.36% Airbnb Rental Income: $1678 Traditional Rental Income: $2541 Airbnb ROI: 1.52% Traditional ROI: 5.36%
1141 WEVERTON Road KNOXVILLE, MD Charming stone cottage set upon nearly 16 acres with beautiful views! Home would be perfec...	1 beds \| 1 baths \| 1,154 sq.ft.	$399,000	Airbnb cash on cash: -0.38% Traditional cash on cash: 2.65% Airbnb Rental Income: $864 Traditional Rental Income: $1666 Airbnb ROI: -0.38% Traditional ROI: 2.65%

Real Estate investment in Knoxville, MD

There are 9 properties for sale in the city of Knoxville . The median list price in Knoxville is $449,000 and the average price per square foot is $176. In August 2026, the average monthly cash on cash return in Knoxville is 3.00%. The average monthly rental income in Knoxville is $2,505.

Knoxville, MD Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 9 investment properties available for sale in Knoxville.

In 2026, the best neighborhood to buy investment property is KNOXVILLE.

The ROI for Long-Term is higher than the Short-Term in Knoxville with average rental income of $2,505.

Your search for investment property begins and ends here

Investment Property for Sale in Knoxville, MD

903 ISRAEL CREEK CT

KNOXVILLE, MD

4 beds | 4 baths | N/A

$759,900

Airbnb cash on cash: 2.71%

Traditional cash on cash: 3.07%

Airbnb Rental Income: $4120

Traditional Rental Income: $3499

Airbnb ROI: 2.71%

Traditional ROI: 3.07%

1411 Jefferson Pike

KNOXVILLE, MD

5 beds | 4 baths | 3,400 sq.ft.

$925,000

Airbnb cash on cash: 1.15%

Traditional cash on cash: 0.64%

Airbnb Rental Income: $3585

Traditional Rental Income: $2342

Airbnb ROI: 1.15%

Traditional ROI: 0.64%

608 Jefferson Pike

KNOXVILLE, MD

4 beds | 2 baths | 4,058 sq.ft.

$950,000

Airbnb cash on cash: 1.7%

Traditional cash on cash: 1.75%

Airbnb Rental Income: $4120

Traditional Rental Income: $3286

Airbnb ROI: 1.7%

Traditional ROI: 1.75%

724 Jefferson Pike

KNOXVILLE, MD

3 beds | 1 baths | 1,800 sq.ft.

$390,000

Airbnb cash on cash: 1.22%

Traditional cash on cash: 4.41%

Airbnb Rental Income: $1678

Traditional Rental Income: $2379

Airbnb ROI: 1.22%

Traditional ROI: 4.41%

230 KNOXVILLE Road

KNOXVILLE, MD

3 beds | 2 baths | 1,496 sq.ft.

$248,000

Airbnb cash on cash: 3.06%

Traditional cash on cash: 7.45%

Airbnb Rental Income: $1678

Traditional Rental Income: $2237

Airbnb ROI: 3.06%

Traditional ROI: 7.45%

Harpers Ferry Rd

KNOXVILLE, MD

3 beds | 2 baths | 1,870 sq.ft.

$577,500

Airbnb cash on cash: 0.84%

Traditional cash on cash: 3.15%

Airbnb Rental Income: $1678

Traditional Rental Income: $2469

Airbnb ROI: 0.84%

Traditional ROI: 3.15%

325 E MOUNTAIN RD

KNOXVILLE, MD

4 beds | 3 baths | N/A

$585,000

Airbnb cash on cash: 3.64%

Traditional cash on cash: 3.37%

Airbnb Rental Income: $4120

Traditional Rental Income: $3099

Airbnb ROI: 3.64%

Traditional ROI: 3.37%

18854 SANDY HOOK Road

KNOXVILLE, MD

3 beds | 2 baths | 2,835 sq.ft.

$370,000

Airbnb cash on cash: 1.52%

Traditional cash on cash: 5.36%

Airbnb Rental Income: $1678

Traditional Rental Income: $2541

Airbnb ROI: 1.52%