Real Estate Investment Properties for Sale in Clarksdale, MS

Looking for investment property in Clarksdale, MS with high ROI ?

Explore a variety of short-term homes & houses in Clarksdale, MS. Invest wisely with VRBO & Clarksdale, MS Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Clarksdale, MS

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
359 Florence Avenue Clarksdale, MS Welcome to this inviting 3 bedroom, 2 bathroom home full of charm and potential. Step insi...	3 beds \| 2 baths \| 2,075 sq.ft.	$165,000	Airbnb cash on cash: 5.54% Traditional cash on cash: 11.32% Airbnb Rental Income: $1735 Traditional Rental Income: $2168 Airbnb ROI: 5.54% Traditional ROI: 11.32%
249 Clark St. Clarksdale, MS Welcome to the prettiest house in Clarksdale, MS.! Birthplace of The Blues! Located...	3 beds \| 2 baths \| 2,300 sq.ft.	$219,000	Airbnb cash on cash: 3.51% Traditional cash on cash: 10.27% Airbnb Rental Income: $1735 Traditional Rental Income: $2659 Airbnb ROI: 3.51% Traditional ROI: 10.27%
333 WESTOVER Clarksdale, MS A true modern architectural masterpiece. E. Fay Jonesâfamous for dramatic residential cr...	4 beds \| 8 baths \| N/A	$649,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.56% Airbnb Rental Income: $null Traditional Rental Income: $5972 Airbnb ROI: N/A Traditional ROI: 6.56%
340 Porter Drive Clarksdale, MS Welcome to your dream home at 340 Porter Drive in Clarksdale, Coahoma County! This impress...	3 beds \| 3 baths \| 3,300 sq.ft.	$350,000	Airbnb cash on cash: 1.61% Traditional cash on cash: 6.1% Airbnb Rental Income: $1735 Traditional Rental Income: $2732 Airbnb ROI: 1.61% Traditional ROI: 6.1%
Investment Properties for Sale in Other Cities of Mississippi
1612 E Northside Dr Jackson , MS You have to see this one in person to appreciate the character. It's a 4-bedroom Tudor tha...	4 beds \| 3 baths \| 2,850 sq.ft.	$429,000	Airbnb cash on cash: 1.46% Traditional cash on cash: 3.93% Airbnb Rental Income: $2036 Traditional Rental Income: $2501 Airbnb ROI: 1.46% Traditional ROI: 3.93%
299 Wood Dale Drive Jackson , MS Rich in history and thoughtfully updated for modern living, this special Fondren home has ...	4 beds \| 3 baths \| 3,317 sq.ft.	$409,000	Airbnb cash on cash: 0.87% Traditional cash on cash: 5.27% Airbnb Rental Income: $1600 Traditional Rental Income: $2830 Airbnb ROI: 0.87% Traditional ROI: 5.27%
1831 Howard Street Jackson , MS This charming Belhaven bungalow presents a warm welcoming to you, your friends, and is a d...	3 beds \| 2 baths \| 1,705 sq.ft.	$244,000	Airbnb cash on cash: 3.22% Traditional cash on cash: 6.36% Airbnb Rental Income: $1682 Traditional Rental Income: $1938 Airbnb ROI: 3.22% Traditional ROI: 6.36%
1622 Poplar Boulevard Jackson , MS Classic Belhaven charm with room to live, work, and entertain! There is a lot of history i...	4 beds \| 4 baths \| 2,436 sq.ft.	$265,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.85% Airbnb Rental Income: $null Traditional Rental Income: $970 Airbnb ROI: N/A Traditional ROI: 0.85%
3325 University Ave Laurel , MS Welcome to this beautiful North Laurel home offering over 2,600 square feet of inviting li...	3 beds \| 3 baths \| 2,646 sq.ft.	$239,900	Airbnb cash on cash: 0.08% Traditional cash on cash: 6.84% Airbnb Rental Income: $850 Traditional Rental Income: $2052 Airbnb ROI: 0.08% Traditional ROI: 6.84%
2230 Ridgewood Drive Laurel , MS Nestled near the heart of charming downtown Laurel, MS, this exquisite 5-bedroom, 3-full b...	5 beds \| 6 baths \| 4,748 sq.ft.	$699,000	Airbnb cash on cash: 0.65% Traditional cash on cash: 7.02% Airbnb Rental Income: $2255 Traditional Rental Income: $5848 Airbnb ROI: 0.65% Traditional ROI: 7.02%
232 Cooper Lane Biloxi , MS Step into this beautifully designed home featuring a well-thought-out interior layout and ...	3 beds \| 3 baths \| 1,796 sq.ft.	$339,900	Airbnb cash on cash: 0.89% Traditional cash on cash: 4.69% Airbnb Rental Income: $1220 Traditional Rental Income: $2040 Airbnb ROI: 0.89% Traditional ROI: 4.69%
416 Beverly Drive Biloxi , MS Spacious and recently updated home situated on a desirable double lot, featuring a double ...	3 beds \| 2 baths \| 2,680 sq.ft.	$296,000	Airbnb cash on cash: 0.76% Traditional cash on cash: 5.65% Airbnb Rental Income: $1220 Traditional Rental Income: $2192 Airbnb ROI: 0.76% Traditional ROI: 5.65%
6401 Ascot Drive Biloxi , MS This stunning home offers the perfect blend of comfort, style, and outdoor living, with be...	3 beds \| 2 baths \| 2,268 sq.ft.	$470,000	Airbnb cash on cash: -0.09% Traditional cash on cash: 4.27% Airbnb Rental Income: $1220 Traditional Rental Income: $2746 Airbnb ROI: -0.09% Traditional ROI: 4.27%
1219 Zentwood Road Tupelo , MS Discover your dream home in Tupelo--this stunning 4-bedroom, 3-bathroom residence is situa...	4 beds \| 3 baths \| 2,605 sq.ft.	$299,900	Airbnb cash on cash: 2.05% Traditional cash on cash: 7.67% Airbnb Rental Income: $1520 Traditional Rental Income: $2664 Airbnb ROI: 2.05% Traditional ROI: 7.67%
387 Caroline Boulevard Madison , MS Golf course and lake views come together at 387 Caroline Blvd in the Lake Caroline communi...	4 beds \| 4 baths \| 3,578 sq.ft.	$645,000	Airbnb cash on cash: -0.5% Traditional cash on cash: 4.7% Airbnb Rental Income: $1155 Traditional Rental Income: $3901 Airbnb ROI: -0.5% Traditional ROI: 4.7%
12 Seminole Drive Picayune , MS Experience the perfect balance of peace and convenience in this meticulously maintained ho...	3 beds \| 2 baths \| 1,714 sq.ft.	$299,900	Airbnb cash on cash: -0.83% Traditional cash on cash: 4.45% Airbnb Rental Income: $606 Traditional Rental Income: $1808 Airbnb ROI: -0.83% Traditional ROI: 4.45%
2212 E Canal Street Picayune , MS Maximize your ROI with this rare dual-income opportunity! This versatile property features...	4 beds \| 2 baths \| 2,068 sq.ft.	$195,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.38% Airbnb Rental Income: $null Traditional Rental Income: $2177 Airbnb ROI: N/A Traditional ROI: 9.38%
2074 Trailwood Drive Biloxi , MS Calling all investors! Property is sold "AS IS". This 1700 sf 3 bedroom and 1.5 bathroom h...	3 beds \| 2 baths \| 1,700 sq.ft.	$189,900	Airbnb cash on cash: 2.31% Traditional cash on cash: 8.05% Airbnb Rental Income: $1220 Traditional Rental Income: $1864 Airbnb ROI: 2.31% Traditional ROI: 8.05%
100 Twin Gates Drive Oxford , MS This attractive Two -story Townhouse in Twin Gates is move in ready for the perfect family...	3 beds \| 3 baths \| 1,560 sq.ft.	$315,000	Airbnb cash on cash: 0.71% Traditional cash on cash: 4.33% Airbnb Rental Income: $1231 Traditional Rental Income: $1912 Airbnb ROI: 0.71% Traditional ROI: 4.33%

Real Estate investment in Clarksdale, MS

There are 4 properties for sale in the city of Clarksdale . The median list price in Clarksdale is $127,350 and the average price per square foot is $56. In May 2026, the average monthly cash on cash return in Clarksdale is 19.00%. The average monthly rental income in Clarksdale is $2,263.

Clarksdale, MS Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 4 investment properties available for sale in Clarksdale.

In 2026, the best neighborhood to buy investment property is Clarksdale.

The ROI for Short-Term is higher than the Long-Term in Clarksdale with average rental income of $1,735.

Your search for investment property begins and ends here

Investment Property for Sale in Clarksdale, MS

359 Florence Avenue

Clarksdale, MS

3 beds | 2 baths | 2,075 sq.ft.

$165,000

Airbnb cash on cash: 5.54%

Traditional cash on cash: 11.32%

Airbnb Rental Income: $1735

Traditional Rental Income: $2168

Airbnb ROI: 5.54%

Traditional ROI: 11.32%

249 Clark St.

Clarksdale, MS

3 beds | 2 baths | 2,300 sq.ft.

$219,000

Airbnb cash on cash: 3.51%

Traditional cash on cash: 10.27%

Airbnb Rental Income: $1735

Traditional Rental Income: $2659

Airbnb ROI: 3.51%

Traditional ROI: 10.27%

333 WESTOVER

Clarksdale, MS

4 beds | 8 baths | N/A

$649,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.56%

Airbnb Rental Income: $null

Traditional Rental Income: $5972

Airbnb ROI: N/A

Traditional ROI: 6.56%

340 Porter Drive

Clarksdale, MS

3 beds | 3 baths | 3,300 sq.ft.

$350,000

Airbnb cash on cash: 1.61%

Traditional cash on cash: 6.1%

Airbnb Rental Income: $1735

Traditional Rental Income: $2732

Airbnb ROI: 1.61%

Traditional ROI: 6.1%

Investment Properties for Sale in Other Cities of Mississippi

Jackson , MS

4 beds | 3 baths | 2,850 sq.ft.

$429,000

Airbnb cash on cash: 1.46%

Traditional cash on cash: 3.93%

Airbnb Rental Income: $2036

Traditional Rental Income: $2501

Airbnb ROI: 1.46%

Traditional ROI: 3.93%

Jackson , MS

4 beds | 3 baths | 3,317 sq.ft.

$409,000

Airbnb cash on cash: 0.87%

Traditional cash on cash: 5.27%

Airbnb Rental Income: $1600

Traditional Rental Income: $2830

Airbnb ROI: 0.87%

Traditional ROI: 5.27%

Jackson , MS

3 beds | 2 baths | 1,705 sq.ft.

$244,000

Airbnb cash on cash: 3.22%

Traditional cash on cash: 6.36%

Airbnb Rental Income: $1682

Traditional Rental Income: $1938

Airbnb ROI: 3.22%

Traditional ROI: 6.36%

Jackson , MS

4 beds | 4 baths | 2,436 sq.ft.

$265,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.85%

Airbnb Rental Income: $null

Traditional Rental Income: $970

Airbnb ROI: N/A

Traditional ROI: 0.85%

Laurel , MS

3 beds | 3 baths | 2,646 sq.ft.