Real Estate Investment Properties for Sale in Florence, MS

Looking for investment property in Florence, MS with high ROI ?

Explore a variety of short-term homes & houses in Florence, MS. Invest wisely with VRBO & Florence, MS Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Florence, MS

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
210 White Street Florence, MS PRICE REDUCED!!! Welcome to 210 White St., where luxury meets comfort in this stunning res...	4 beds \| 3 baths \| 3,706 sq.ft.	$599,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.06% Airbnb Rental Income: $null Traditional Rental Income: $2846 Airbnb ROI: N/A Traditional ROI: 3.06%
133 Monmouth Road Florence, MS Beautiful 3-bedroom, 2-bath home offering the perfect blend of southern charm and modern u...	3 beds \| 2 baths \| 1,924 sq.ft.	$274,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.65% Airbnb Rental Income: $null Traditional Rental Income: $2176 Airbnb ROI: N/A Traditional ROI: 6.65%
2244 Florence Byram Road Florence, MS Spacious and versatile, this 2,643 sq ft home built in 2004 sits on a beautiful 2-acre lot...	4 beds \| 2 baths \| 2,643 sq.ft.	$359,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.68% Airbnb Rental Income: $null Traditional Rental Income: $2467 Airbnb ROI: N/A Traditional ROI: 5.68%
118 Pine Ridge Road Florence, MS 100% Financing USDA Zone home in the Cleary Lake community of Florence, MS. Seller will co...	3 beds \| 2 baths \| 2,115 sq.ft.	$279,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.68% Airbnb Rental Income: $null Traditional Rental Income: $1707 Airbnb ROI: N/A Traditional ROI: 4.68%
2112 Cleary Road Florence, MS Well-maintained 3BR/2BA home in a desirable location close to shopping, dining, schools, a...	3 beds \| 2 baths \| 1,616 sq.ft.	$268,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.46% Airbnb Rental Income: $null Traditional Rental Income: $1797 Airbnb ROI: N/A Traditional ROI: 5.46%
1459 Monterey Road Florence, MS Stunning Remodeled Home with Spacious Addition on 11.9 Acres in Florence School District D...	5 beds \| 3 baths \| 3,316 sq.ft.	$499,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.77% Airbnb Rental Income: $null Traditional Rental Income: $2928 Airbnb ROI: N/A Traditional ROI: 4.77%
206 Lewis Street Florence, MS This amazing home features 4 bedroom/2.5 bathroom with beautiful updated floors, kitchen, ...	4 beds \| 3 baths \| 2,553 sq.ft.	$311,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.3% Airbnb Rental Income: $null Traditional Rental Income: $2802 Airbnb ROI: N/A Traditional ROI: 7.3%
297 Barnes Road Florence, MS The owners will sell 10 to 23 acre lakefront homesite tracts, if so desired, from $194,900...	5 beds \| 5 baths \| 4,474 sq.ft.	$1,590,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.07% Airbnb Rental Income: $null Traditional Rental Income: $5046 Airbnb ROI: N/A Traditional ROI: 2.07%
1511 S Hwy 469 Florence, MS Built in 2007 this Residence was featured in Mississippi Magazine's September/October 2010...	4 beds \| 5 baths \| 4,980 sq.ft.	$1,590,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.19% Airbnb Rental Income: $null Traditional Rental Income: $5129 Airbnb ROI: N/A Traditional ROI: 2.19%
1118 Gunter Road Florence, MS SIGNIFICANT PRICE REDUCTION!! This immaculate, well-maintained 3-bedroom home sits on just...	3 beds \| 2 baths \| 1,649 sq.ft.	$260,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.73% Airbnb Rental Income: $null Traditional Rental Income: $1801 Airbnb ROI: N/A Traditional ROI: 5.73%
306 Cedar Stone Court Florence, MS Welcome to 306 Cedar Stone Court, arguably the best spot on the cul-de-sac in the beautifu...	4 beds \| 3 baths \| 2,244 sq.ft.	$365,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.94% Airbnb Rental Income: $null Traditional Rental Income: $2390 Airbnb ROI: N/A Traditional ROI: 4.94%
528 Camellia Lane Florence, MS This is a cute 4 bedroom, 2 baths home in the famous Florence Gardens subdivision. It incl...	4 beds \| 2 baths \| 1,663 sq.ft.	$198,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.51% Airbnb Rental Income: $null Traditional Rental Income: $2097 Airbnb ROI: N/A Traditional ROI: 9.51%
146 Richmond Drive Florence, MS MOVE TO FLORENCE!! NEW PRICE This lovely 3 bedroom 2 bath home was custom built in 2006 ju...	3 beds \| 2 baths \| 2,044 sq.ft.	$335,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.89% Airbnb Rental Income: $null Traditional Rental Income: $2404 Airbnb ROI: N/A Traditional ROI: 5.89%
302 N Church Street Florence, MS Charming home in the heart of Florence with a recently replaced roof. Inside you'll find s...	3 beds \| 2 baths \| 1,835 sq.ft.	$249,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.7% Airbnb Rental Income: $null Traditional Rental Income: $1526 Airbnb ROI: N/A Traditional ROI: 4.7%
922 Mullican Road Florence, MS Tucked away on a 2.55-acre wooded lot, this new construction home was just completed and o...	4 beds \| 3 baths \| 2,350 sq.ft.	$482,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.48% Airbnb Rental Income: $null Traditional Rental Income: $2606 Airbnb ROI: N/A Traditional ROI: 4.48%
322 Tremont Drive Florence, MS Great 4 Bedroom 3 Bathroom home in the Newest Neighborhood in Florence! This Open Concept ...	4 beds \| 3 baths \| 1,930 sq.ft.	$354,600	Airbnb cash on cash: N/A Traditional cash on cash: 4.24% Airbnb Rental Income: $null Traditional Rental Income: $2154 Airbnb ROI: N/A Traditional ROI: 4.24%
1460 Highway 469 Florence, MS I would live here! This one is a wonderful find! Set back off the road on at least an acre...	3 beds \| 3 baths \| 2,080 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.85% Airbnb Rental Income: $null Traditional Rental Income: $2480 Airbnb ROI: N/A Traditional ROI: 6.85%
939 Mullican Road Florence, MS Well-designed new construction on 3.71 acres in Mullican Place of Florence, this 4 bedroom...	4 beds \| 3 baths \| 2,120 sq.ft.	$445,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.4% Airbnb Rental Income: $null Traditional Rental Income: $2385 Airbnb ROI: N/A Traditional ROI: 4.4%
204 Magnolia Springs Boulevard Florence, MS Welcome to 204 Magnolia Springs in the Magnolia subdivision! This spacious home features 4...	4 beds \| 3 baths \| 2,546 sq.ft.	$464,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.67% Airbnb Rental Income: $null Traditional Rental Income: $2310 Airbnb ROI: N/A Traditional ROI: 3.67%
216 Cactus Court Florence, MS Nestled within an exclusive gated community, this exceptional 4-bedroom, 3.5-bath luxury p...	4 beds \| 4 baths \| 2,843 sq.ft.	$560,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.72% Airbnb Rental Income: $null Traditional Rental Income: $2897 Airbnb ROI: N/A Traditional ROI: 3.72%
2612 W Mountain Creek Road Florence, MS Charming home in the country! Relax on the deck as you look across your little slice of he...	2 beds \| 2 baths \| 1,100 sq.ft.	$125,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.31% Airbnb Rental Income: $null Traditional Rental Income: $1241 Airbnb ROI: N/A Traditional ROI: 8.31%
302 Tremont Drive Florence, MS Great 4 Bedroom 3 Bathroom home in the Newest Neighborhood in Florence! This Open Concept ...	4 beds \| 3 baths \| 1,944 sq.ft.	$355,800	Airbnb cash on cash: N/A Traditional cash on cash: 4.21% Airbnb Rental Income: $null Traditional Rental Income: $2150 Airbnb ROI: N/A Traditional ROI: 4.21%
304 Tremont Drive Florence, MS Great 4 Bedroom 3 Bathroom home in the Newest Neighborhood in Florence! This Open Concept ...	4 beds \| 3 baths \| 1,975 sq.ft.	$361,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.27% Airbnb Rental Income: $null Traditional Rental Income: $2202 Airbnb ROI: N/A Traditional ROI: 4.27%
185 W Neal Road Florence, MS Priced $48,000 under appraised value!!!! 100% USDA financing available to qualified buyers...	3 beds \| 4 baths \| 4,146 sq.ft.	$524,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.46% Airbnb Rental Income: $null Traditional Rental Income: $3523 Airbnb ROI: N/A Traditional ROI: 5.46%
2253 Cleary Road Florence, MS Welcome to your own slice of country comfort at 2253 Cleary Rd in Florence, MS! Sitting on...	3 beds \| 2 baths \| 1,687 sq.ft.	$239,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.74% Airbnb Rental Income: $null Traditional Rental Income: $1725 Airbnb ROI: N/A Traditional ROI: 5.74%
120 Monmouth Road Florence, MS NEW PRICE!!! Welcome to this adorable home in Florence MS with a breathtaking lake view.. ...	2 beds \| 2 baths \| 1,602 sq.ft.	$215,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.69% Airbnb Rental Income: $null Traditional Rental Income: $2148 Airbnb ROI: N/A Traditional ROI: 8.69%
219 Bass Road Florence, MS A Rare Opportunity on Five Acres! Once a thriving country nursing home, this unique sprawl...	12 beds \| 7 baths \| 7,401 sq.ft.	$945,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.79% Airbnb Rental Income: $null Traditional Rental Income: $5661 Airbnb ROI: N/A Traditional ROI: 4.79%
145 Margaret Lane Florence, MS NEW LISTING IN FLORENCE with over 3300 square feet! Discover your dream home with stunning...	4 beds \| 3 baths \| 3,335 sq.ft.	$374,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.25% Airbnb Rental Income: $null Traditional Rental Income: $2926 Airbnb ROI: N/A Traditional ROI: 6.25%
250 Lewis Road S Florence, MS Enjoy peaceful country living on a full acre with plenty of space to spread out. This 4 be...	4 beds \| 2 baths \| 1,825 sq.ft.	$185,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.1% Airbnb Rental Income: $null Traditional Rental Income: $2287 Airbnb ROI: N/A Traditional ROI: 11.1%
206 Barrington Cove Florence, MS Welcome to 206 Barrington Cove, a lovely 3-bedroom, 2-bath home located in a beautiful nei...	3 beds \| 2 baths \| 1,457 sq.ft.	$250,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.39% Airbnb Rental Income: $null Traditional Rental Income: $1509 Airbnb ROI: N/A Traditional ROI: 4.39%
499 Old Enochs Road Florence, MS Welcome to this 3 bedroom, 2 bathroom mobile home set on 5 acres in Florence, MS. If you'v...	3 beds \| 2 baths \| 1,920 sq.ft.	$250,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.12% Airbnb Rental Income: $null Traditional Rental Income: $1668 Airbnb ROI: N/A Traditional ROI: 5.12%
111 Colebrooke Cove Florence, MS Don't walk.. RUN to this one! This practically new home in Florence's sought-after Colebro...	3 beds \| 3 baths \| 2,221 sq.ft.	$385,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.49% Airbnb Rental Income: $null Traditional Rental Income: $2305 Airbnb ROI: N/A Traditional ROI: 4.49%
107 Copper Ridge Lane Florence, MS Located less than a mile from A-rated Steen's Creek Elementary School, this 3-bedroom, 2-b...	3 beds \| 2 baths \| 1,671 sq.ft.	$235,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.71% Airbnb Rental Income: $null Traditional Rental Income: $1547 Airbnb ROI: N/A Traditional ROI: 4.71%
105 Point Clear Florence, MS Come experience the peaceful charm and stunning panoramic lake views at 105 Point Clear. W...	3 beds \| 2 baths \| 1,926 sq.ft.	$255,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.24% Airbnb Rental Income: $null Traditional Rental Income: $2486 Airbnb ROI: N/A Traditional ROI: 8.24%
119 Copper Ridge Lane Florence, MS This 3-bedroom, 2-bath home offers spacious living areas. The living area includes a trey ...	3 beds \| 2 baths \| 1,694 sq.ft.	$229,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.86% Airbnb Rental Income: $null Traditional Rental Income: $1733 Airbnb ROI: N/A Traditional ROI: 5.86%
401 Roxbury Place Florence, MS 401 Roxbury Place - Florence Beautiful home featuring hardwood floorsthroughout the living...	3 beds \| 2 baths \| 1,502 sq.ft.	$249,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.88% Airbnb Rental Income: $null Traditional Rental Income: $1645 Airbnb ROI: N/A Traditional ROI: 4.88%
602 Madeline Cove Florence, MS Price Reduced! Seller offering $4,000 in Concessions/Closing Costs! Welcome to 602 Madelin...	3 beds \| 2 baths \| 1,480 sq.ft.	$229,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.21% Airbnb Rental Income: $null Traditional Rental Income: $1695 Airbnb ROI: N/A Traditional ROI: 5.21%
526 Brighton Trail Florence, MS Welcome to 526 Brighton Trail in Florence! This 4 bedroom, 2 bathroom home offers 1,555 sq...	4 beds \| 2 baths \| 1,555 sq.ft.	$260,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.19% Airbnb Rental Income: $null Traditional Rental Income: $1776 Airbnb ROI: N/A Traditional ROI: 5.19%
246 Ella Lane Florence, MS Charming 3-bedroom, 2-bath home situated on a spacious 0.61-acre lot! Updated just 2.5 yea...	3 beds \| 2 baths \| 1,350 sq.ft.	$219,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.53% Airbnb Rental Income: $null Traditional Rental Income: $1517 Airbnb ROI: N/A Traditional ROI: 5.53%
559 White Oak Road Florence, MS Located in a highly regarded school district in Florence, this property sits on 2 acres of...	4 beds \| 4 baths \| 4,450 sq.ft.	$539,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.53% Airbnb Rental Income: $null Traditional Rental Income: $3506 Airbnb ROI: N/A Traditional ROI: 4.53%

Real Estate investment in Florence, MS

There are 46 properties for sale in the city of Florence . The median list price in Florence is $279,500 and the average price per square foot is $129. In May 2026, the average monthly cash on cash return in Florence is 5.00%. The average monthly rental income in Florence is $2,202.

Florence, MS Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 46 investment properties available for sale in Florence.

The ROI for Short-Term is higher than the Long-Term in Florence with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Florence, MS

210 White Street

Florence, MS

4 beds | 3 baths | 3,706 sq.ft.

$599,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.06%

Airbnb Rental Income: $null

Traditional Rental Income: $2846

Airbnb ROI: N/A

Traditional ROI: 3.06%

133 Monmouth Road

Florence, MS

3 beds | 2 baths | 1,924 sq.ft.

$274,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.65%

Airbnb Rental Income: $null

Traditional Rental Income: $2176

Airbnb ROI: N/A

Traditional ROI: 6.65%

2244 Florence Byram Road

Florence, MS

4 beds | 2 baths | 2,643 sq.ft.

$359,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.68%

Airbnb Rental Income: $null

Traditional Rental Income: $2467

Airbnb ROI: N/A

Traditional ROI: 5.68%

118 Pine Ridge Road

Florence, MS

3 beds | 2 baths | 2,115 sq.ft.

$279,900

Airbnb cash on cash: N/A

Traditional cash on cash: 4.68%

Airbnb Rental Income: $null

Traditional Rental Income: $1707

Airbnb ROI: N/A

Traditional ROI: 4.68%

2112 Cleary Road

Florence, MS

3 beds | 2 baths | 1,616 sq.ft.

$268,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.46%

Airbnb Rental Income: $null

Traditional Rental Income: $1797

Airbnb ROI: N/A

Traditional ROI: 5.46%

1459 Monterey Road

Florence, MS

5 beds | 3 baths | 3,316 sq.ft.

$499,900

Airbnb cash on cash: N/A

Traditional cash on cash: 4.77%

Airbnb Rental Income: $null

Traditional Rental Income: $2928

Airbnb ROI: N/A

Traditional ROI: 4.77%

206 Lewis Street

Florence, MS

4 beds | 3 baths | 2,553 sq.ft.

$311,500

Airbnb cash on cash: N/A

Traditional cash on cash: 7.3%

Airbnb Rental Income: $null

Traditional Rental Income: $2802

Airbnb ROI: N/A

Traditional ROI: 7.3%

297 Barnes Road

Florence, MS

5 beds | 5 baths | 4,474 sq.ft.

$1,590,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.07%

Airbnb Rental Income: $null

Traditional Rental Income: $5046

Airbnb ROI: N/A