Real Estate Investment Properties for Sale in Florence, MS

Looking for investment property in Florence, MS with high ROI ?

Explore a variety of short-term homes & houses in Florence, MS. Invest wisely with VRBO & Florence, MS Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Florence, MS

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
210 White Street Florence, MS HUGE PRICE REDUCTION!! Welcome to 210 White St., where luxury meets comfort in this stunni...	4 beds \| 3 baths \| 3,706 sq.ft.	$649,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.75% Airbnb Rental Income: $null Traditional Rental Income: $2846 Airbnb ROI: N/A Traditional ROI: 2.75%
266 Country Hills Drive Florence, MS Rare opportunity to find a home in the Country Hills Subdivision! This home is an absolute...	4 beds \| 3 baths \| 2,646 sq.ft.	$450,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.86% Airbnb Rental Income: $null Traditional Rental Income: $3236 Airbnb ROI: N/A Traditional ROI: 5.86%
1043 Spanish Oak Boulevard Florence, MS Price reduced! Welcome to 1043 Spanish Oaks Boulevard--an adorable 3-bedroom, 2-bath home ...	3 beds \| 2 baths \| 1,449 sq.ft.	$214,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.17% Airbnb Rental Income: $null Traditional Rental Income: $1764 Airbnb ROI: N/A Traditional ROI: 6.17%
600 Madeline Cove Florence, MS This 3-bedroom, 2-bath home in Florence, MS features a cozy living room with a fireplace, ...	3 beds \| 2 baths \| 1,391 sq.ft.	$194,500	Airbnb cash on cash: N/A Traditional cash on cash: 6.6% Airbnb Rental Income: $null Traditional Rental Income: $1738 Airbnb ROI: N/A Traditional ROI: 6.6%
729 N Church Street Florence, MS This charming home is move-in ready. New floors, countertops, fresh paint and so much more...	3 beds \| 1 baths \| 1,450 sq.ft.	$245,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.84% Airbnb Rental Income: $null Traditional Rental Income: $1545 Airbnb ROI: N/A Traditional ROI: 4.84%
203 Wethersfield Drive Florence, MS Seller says this one HAS TO GO! Notice the improved list price. This one is the BEST pri...	4 beds \| 3 baths \| 2,053 sq.ft.	$357,200	Airbnb cash on cash: N/A Traditional cash on cash: 4.9% Airbnb Rental Income: $null Traditional Rental Income: $2386 Airbnb ROI: N/A Traditional ROI: 4.9%
204 Wethersfield Drive Florence, MS Great 4 Bedroom 3 Bathroom home in the Newest Neighborhood in Florence! This Open Concept...	4 beds \| 3 baths \| 2,060 sq.ft.	$355,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.93% Airbnb Rental Income: $null Traditional Rental Income: $2386 Airbnb ROI: N/A Traditional ROI: 4.93%
208 Wethersfield Drive Florence, MS Great 4 Bedroom 3 Bathroom home in the Newest Neighborhood in Florence! This Open Concept ...	4 beds \| 3 baths \| 2,044 sq.ft.	$352,600	Airbnb cash on cash: N/A Traditional cash on cash: 4.95% Airbnb Rental Income: $null Traditional Rental Income: $2376 Airbnb ROI: N/A Traditional ROI: 4.95%
148 Stanton Hall Drive Florence, MS Welcome home to this stunning custom-built retreat, perfectly tucked away near the end of ...	3 beds \| 3 baths \| 2,818 sq.ft.	$397,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.7% Airbnb Rental Income: $null Traditional Rental Income: $2480 Airbnb ROI: N/A Traditional ROI: 4.7%
115 Lakeland Drive Florence, MS PRICE REDUCED!!!!Waterfront!!! Pool!! Welcome to your dream oasis at 115 Lakeland Dr., Flo...	3 beds \| 3 baths \| 2,600 sq.ft.	$399,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.92% Airbnb Rental Income: $null Traditional Rental Income: $2857 Airbnb ROI: N/A Traditional ROI: 5.92%
206 Lewis Street Florence, MS This amazing home features 4 bedroom/2.5 bathroom with beautiful updated floors, kitchen, ...	4 beds \| 3 baths \| 2,553 sq.ft.	$319,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.11% Airbnb Rental Income: $null Traditional Rental Income: $2802 Airbnb ROI: N/A Traditional ROI: 7.11%
559 White Oak Road Florence, MS This exceptional 4-bedroom, 4-bathroom home, built as a personal residence by a custom hom...	4 beds \| 4 baths \| 4,450 sq.ft.	$574,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.19% Airbnb Rental Income: $null Traditional Rental Income: $3506 Airbnb ROI: N/A Traditional ROI: 4.19%
448 Thomasville Road Florence, MS Do you dream of owning your own farmland in Rankin County without having to start from scr...	5 beds \| 3 baths \| 3,031 sq.ft.	$900,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.32% Airbnb Rental Income: $null Traditional Rental Income: $3172 Airbnb ROI: N/A Traditional ROI: 2.32%
500 E Dewey Camp Drive Florence, MS ALL BRICK CUSTOM HOME with lots of Detail at HOOVER LAKE! Boating and Fishing Enjoyed! 3/...	3 beds \| 2 baths \| 1,658 sq.ft.	$263,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.65% Airbnb Rental Income: $null Traditional Rental Income: $1886 Airbnb ROI: N/A Traditional ROI: 5.65%
130 Nevels Drive Florence, MS Beautiful 4-Bedroom Home on 6.5 Acres with small pond.Welcome to your ideal retreat in thi...	4 beds \| 4 baths \| 3,303 sq.ft.	$320,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.36% Airbnb Rental Income: $null Traditional Rental Income: $3326 Airbnb ROI: N/A Traditional ROI: 9.36%
297 Barnes Road Florence, MS Welcome to 297 Barnes Road -- a stunning modern gothic farmhouse set on nearly 57 secluded...	5 beds \| 5 baths \| 4,474 sq.ft.	$1,590,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.07% Airbnb Rental Income: $null Traditional Rental Income: $5046 Airbnb ROI: N/A Traditional ROI: 2.07%
1511 S Hwy 469 Florence, MS Built in 2007 this Residence was featured in Mississippi Magazine's September/October 2010...	4 beds \| 5 baths \| 4,980 sq.ft.	$1,790,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.83% Airbnb Rental Income: $null Traditional Rental Income: $5129 Airbnb ROI: N/A Traditional ROI: 1.83%
1118 Gunter Road Florence, MS Prime location for your RESIDENCE or BUSINESS or both! Conveniently located near the traff...	3 beds \| 2 baths \| 1,649 sq.ft.	$375,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.7% Airbnb Rental Income: $null Traditional Rental Income: $1801 Airbnb ROI: N/A Traditional ROI: 3.7%
353 Flinco Farms Road Florence, MS A Timeless Farmhouse Retreat on 36 Acres 🌿Welcome to your private sanctuary, where...	4 beds \| 4 baths \| 3,052 sq.ft.	$998,500	Airbnb cash on cash: N/A Traditional cash on cash: 2.68% Airbnb Rental Income: $null Traditional Rental Income: $3761 Airbnb ROI: N/A Traditional ROI: 2.68%
140 Dixie Road Florence, MS Must see! This beautiful home includes 3 bedrooms/1 bath of character and charm. Spacio...	3 beds \| 1 baths \| 1,220 sq.ft.	$184,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.05% Airbnb Rental Income: $null Traditional Rental Income: $1356 Airbnb ROI: N/A Traditional ROI: 6.05%
182 W Main Street Florence, MS Charming 3-Bedroom Home on 1.3 Acres in Florence! Enjoy peaceful country living with conve...	3 beds \| 2 baths \| 1,550 sq.ft.	$239,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.17% Airbnb Rental Income: $null Traditional Rental Income: $1733 Airbnb ROI: N/A Traditional ROI: 6.17%

Real Estate investment in Florence, MS

There are 29 properties for sale in the city of Florence . The median list price in Florence is $354,050 and the average price per square foot is $149. In October 2025, the average monthly cash on cash return in Florence is 5.00%. The average monthly rental income in Florence is $2,370.

Florence, MS Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 29 investment properties available for sale in Florence.

The ROI for Short-Term is higher than the Long-Term in Florence with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Florence, MS

210 White Street

Florence, MS

4 beds | 3 baths | 3,706 sq.ft.

$649,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.75%

Airbnb Rental Income: $null

Traditional Rental Income: $2846

Airbnb ROI: N/A

Traditional ROI: 2.75%

266 Country Hills Drive

Florence, MS

4 beds | 3 baths | 2,646 sq.ft.

$450,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.86%

Airbnb Rental Income: $null

Traditional Rental Income: $3236

Airbnb ROI: N/A

Traditional ROI: 5.86%

1043 Spanish Oak Boulevard

Florence, MS

3 beds | 2 baths | 1,449 sq.ft.

$214,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.17%

Airbnb Rental Income: $null

Traditional Rental Income: $1764

Airbnb ROI: N/A

Traditional ROI: 6.17%

600 Madeline Cove

Florence, MS

3 beds | 2 baths | 1,391 sq.ft.

$194,500

Airbnb cash on cash: N/A

Traditional cash on cash: 6.6%

Airbnb Rental Income: $null

Traditional Rental Income: $1738

Airbnb ROI: N/A

Traditional ROI: 6.6%

729 N Church Street

Florence, MS

3 beds | 1 baths | 1,450 sq.ft.

$245,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.84%

Airbnb Rental Income: $null

Traditional Rental Income: $1545

Airbnb ROI: N/A

Traditional ROI: 4.84%

203 Wethersfield Drive

Florence, MS

4 beds | 3 baths | 2,053 sq.ft.

$357,200

Airbnb cash on cash: N/A

Traditional cash on cash: 4.9%

Airbnb Rental Income: $null

Traditional Rental Income: $2386

Airbnb ROI: N/A

Traditional ROI: 4.9%

204 Wethersfield Drive

Florence, MS

4 beds | 3 baths | 2,060 sq.ft.

$355,500

Airbnb cash on cash: N/A

Traditional cash on cash: 4.93%

Airbnb Rental Income: $null

Traditional Rental Income: $2386

Airbnb ROI: N/A

Traditional ROI: 4.93%

208 Wethersfield Drive

Florence, MS

4 beds | 3 baths | 2,044 sq.ft.

$352,600

Airbnb cash on cash: N/A

Traditional cash on cash: 4.95%

Airbnb Rental Income: $null

Traditional Rental Income: $2376

Airbnb ROI: N/A