Real Estate Investment Properties for Sale in Picayune, MS

Looking for investment property in Picayune, MS with high ROI ?

Explore a variety of short-term homes & houses in Picayune, MS. Invest wisely with VRBO & Picayune, MS Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Picayune, MS

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
526 Country Club Drive Picayune, MS Move in ready! Cute as a button with plenty of space. Open living./ dining area, breakfast...	3 beds \| 2 baths \| 1,882 sq.ft.	$219,900	Airbnb cash on cash: 0.48% Traditional cash on cash: 7.96% Airbnb Rental Income: $887 Traditional Rental Income: $2107 Airbnb ROI: 0.48% Traditional ROI: 7.96%
8 Jennie Lane Picayune, MS This charming brick home is almost 2800 square feet heated/cooled on over 2 acres. Feature...	4 beds \| 3 baths \| 2,757 sq.ft.	$429,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.66% Airbnb Rental Income: $null Traditional Rental Income: $2691 Airbnb ROI: N/A Traditional ROI: 4.66%
435 Millbrook Parkway Picayune, MS Well maintained home fronting GOLF COURSE! Large walk-in closets and kitchen pantry. Tota...	3 beds \| 2 baths \| 2,036 sq.ft.	$254,000	Airbnb cash on cash: 0.4% Traditional cash on cash: 7.28% Airbnb Rental Income: $887 Traditional Rental Income: $2201 Airbnb ROI: 0.4% Traditional ROI: 7.28%
11 Rosewood Dr. Picayune, MS Showcasing a remarkable four-bedroom, two-bathroom brick residence, encompassing 1800 squa...	4 beds \| 2 baths \| 1,804 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.77% Airbnb Rental Income: $null Traditional Rental Income: $2196 Airbnb ROI: N/A Traditional ROI: 6.77%
319 Dozier St Picayune, MS Roomy 3 bed/ 2 bath home originally built in 1945 that is perfect for a young family or a ...	3 beds \| 2 baths \| 1,485 sq.ft.	$175,000	Airbnb cash on cash: 0.94% Traditional cash on cash: 8.54% Airbnb Rental Income: $887 Traditional Rental Income: $1816 Airbnb ROI: 0.94% Traditional ROI: 8.54%
820 Mitchell St. Picayune, MS If you are looking for a very well maintained 3 bedroom 2 bath home, this is the one! Very...	3 beds \| 2 baths \| N/A	$208,900	Airbnb cash on cash: 0.51% Traditional cash on cash: 7.14% Airbnb Rental Income: $887 Traditional Rental Income: $1864 Airbnb ROI: 0.51% Traditional ROI: 7.14%
1404 Neal Rd Picayune, MS This spacious ranch style home features a huge family room with a woodburning fireplace; b...	3 beds \| 3 baths \| 3,047 sq.ft.	$393,000	Airbnb cash on cash: -0.56% Traditional cash on cash: 5.06% Airbnb Rental Income: $887 Traditional Rental Income: $2621 Airbnb ROI: -0.56% Traditional ROI: 5.06%
628 Telly Rd Picayune, MS Beautiful remodeled 3 bed 2 bath sitting on .77 acres in the city limits of Picayune. Welc...	3 beds \| 2 baths \| 1,750 sq.ft.	$234,900	Airbnb cash on cash: 0.25% Traditional cash on cash: 6.38% Airbnb Rental Income: $887 Traditional Rental Income: $1911 Airbnb ROI: 0.25% Traditional ROI: 6.38%
54 Oak Point Rd Picayune, MS Escape to this picture-perfect 2-bedroom, 1-bathroom riverfront home, rebuilt from the sub...	2 beds \| 2 baths \| 1,010 sq.ft.	$149,500	Airbnb cash on cash: -2.93% Traditional cash on cash: 8.85% Airbnb Rental Income: $145 Traditional Rental Income: $1617 Airbnb ROI: -2.93% Traditional ROI: 8.85%
24327 Rester Road Picayune, MS 3br, 2 bath home with an office on 4.8 acres with vaulted ceiling in family room, wood bur...	3 beds \| 2 baths \| 1,797 sq.ft.	$383,950	Airbnb cash on cash: -0.12% Traditional cash on cash: 3.97% Airbnb Rental Income: $887 Traditional Rental Income: $2023 Airbnb ROI: -0.12% Traditional ROI: 3.97%
2107 Sheppard Blvd Picayune, MS MOVE IN READY!! This is a 3 bedroom 2 bathroom home with an extra room/office space, could...	3 beds \| 2 baths \| 1,895 sq.ft.	$245,000	Airbnb cash on cash: 0.17% Traditional cash on cash: 6.49% Airbnb Rental Income: $887 Traditional Rental Income: $2013 Airbnb ROI: 0.17% Traditional ROI: 6.49%
902 Laird St. Picayune, MS Excellent starter home. Recently remodeled to include all new flooring, bathroom, and kitc...	3 beds \| 1 baths \| 1,221 sq.ft.	$175,000	Airbnb cash on cash: 0.94% Traditional cash on cash: 6.66% Airbnb Rental Income: $887 Traditional Rental Income: $1504 Airbnb ROI: 0.94% Traditional ROI: 6.66%
25541 Broadridge Drive Picayune, MS WOW, what a unique find! This diamond in the rough is one of a kind and filled with charac...	4 beds \| 2 baths \| 2,339 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.95% Airbnb Rental Income: $null Traditional Rental Income: $2213 Airbnb ROI: N/A Traditional ROI: 6.95%
7711 Cuevas Town Road Picayune, MS Price Improvement Country Living at Its Finest! This stunning 4-bedroom, 5-bathroom ...	4 beds \| 5 baths \| 3,566 sq.ft.	$579,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.59% Airbnb Rental Income: $null Traditional Rental Income: $3380 Airbnb ROI: N/A Traditional ROI: 4.59%
701 CARROLL ST Picayune, MS EXCELLENT RENTAL OPPORFTUNITY FOR INVESTOR-ALL UNITS ARE OCCUPIED-GREAT NEIGHBORHOOD-DOUBL...	5 beds \| 3 baths \| 2,288 sq.ft.	$265,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.84% Airbnb Rental Income: $null Traditional Rental Income: $2387 Airbnb ROI: N/A Traditional ROI: 6.84%
703 CARROLL ST Picayune, MS EXCELLENT RENTAL INVESTMENT - GREAT NEIGHBORHOOD - ELEMENTARY SCHOOL NEAR PROPERTY - PROPE...	5 beds \| 3 baths \| 2,288 sq.ft.	$265,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.84% Airbnb Rental Income: $null Traditional Rental Income: $2387 Airbnb ROI: N/A Traditional ROI: 6.84%
123 Tennyson Cove Picayune, MS Step into comfort and charm with this gorgeous 3-bedroom, 2-bath brick home surrounded by ...	3 beds \| 2 baths \| 1,487 sq.ft.	$189,000	Airbnb cash on cash: 0.99% Traditional cash on cash: 6.7% Airbnb Rental Income: $887 Traditional Rental Income: $1576 Airbnb ROI: 0.99% Traditional ROI: 6.7%
38 Wyatt Lane Picayune, MS Precious Acadian-style 3 bedroom, 2 bathroom home sitting on 2 beautiful acres in the coun...	3 beds \| 2 baths \| 1,572 sq.ft.	$247,900	Airbnb cash on cash: 0.08% Traditional cash on cash: 5.22% Airbnb Rental Income: $887 Traditional Rental Income: $1755 Airbnb ROI: 0.08% Traditional ROI: 5.22%
204 S Monroe Picayune, MS Beautiful 3 bedroom, 2 bath Home features a spacious kitchen with stainless steel Samsung ...	3 beds \| 2 baths \| 1,500 sq.ft.	$179,900	Airbnb cash on cash: 0.87% Traditional cash on cash: 7.33% Airbnb Rental Income: $887 Traditional Rental Income: $1656 Airbnb ROI: 0.87% Traditional ROI: 7.33%
552 Fairway Dr Picayune, MS Gorgeous 4 bedroom 2 bath home Custom home with breathtaking views of the golf course! The...	4 beds \| 2 baths \| 1,962 sq.ft.	$339,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.71% Airbnb Rental Income: $null Traditional Rental Income: $2167 Airbnb ROI: N/A Traditional ROI: 4.71%
3624 Highway 43 N Picayune, MS Cute country cottage set in the center of a large 2.5 acre lot with quick and easy access ...	3 beds \| 2 baths \| 1,167 sq.ft.	$230,000	Airbnb cash on cash: 0.3% Traditional cash on cash: 6.76% Airbnb Rental Income: $887 Traditional Rental Income: $1957 Airbnb ROI: 0.3% Traditional ROI: 6.76%
16 Dan Stewart Rd. Picayune, MS Better than new! This pristine 3-bedroom, 2-bath home is just over a year old and sits on ...	3 beds \| 2 baths \| 1,400 sq.ft.	$279,900	Airbnb cash on cash: -0.07% Traditional cash on cash: 5.3% Airbnb Rental Income: $887 Traditional Rental Income: $1967 Airbnb ROI: -0.07% Traditional ROI: 5.3%
560 Fairway Dr Picayune, MS This CUSTOM built modern New Orleans style shotgun house has 3 bedrooms and 2 full baths. ...	3 beds \| 2 baths \| 1,838 sq.ft.	$322,000	Airbnb cash on cash: -0.29% Traditional cash on cash: 4.49% Airbnb Rental Income: $887 Traditional Rental Income: $1997 Airbnb ROI: -0.29% Traditional ROI: 4.49%
3007 Fairway Drive Picayune, MS Don't miss out on this fantastic opportunity in the heart of Picayune! This custom-built 3...	3 beds \| 2 baths \| 1,778 sq.ft.	$321,000	Airbnb cash on cash: 0.35% Traditional cash on cash: 5.24% Airbnb Rental Income: $887 Traditional Rental Income: $2027 Airbnb ROI: 0.35% Traditional ROI: 5.24%
221 S Curran Avenue Picayune, MS Recently Renovated to bring up to current features including adding a primary bedroom and ...	3 beds \| 2 baths \| 1,554 sq.ft.	$199,000	Airbnb cash on cash: 0.77% Traditional cash on cash: 8.1% Airbnb Rental Income: $887 Traditional Rental Income: $1936 Airbnb ROI: 0.77% Traditional ROI: 8.1%
1312 N Beech St Picayune, MS Well maintained older home 3 bedrooms 1 bath-large living room and dining room combined-ni...	3 beds \| 1 baths \| 1,246 sq.ft.	$165,000	Airbnb cash on cash: 1.44% Traditional cash on cash: 7.69% Airbnb Rental Income: $887 Traditional Rental Income: $1534 Airbnb ROI: 1.44% Traditional ROI: 7.69%
1705 Audubon Drive Picayune, MS BACK ON THE MARKET AT NO FAULT OF THE SELLERS! PRICE REDUCED BELOW APPRAISAL! NEW UPDATES ...	3 beds \| 2 baths \| 1,210 sq.ft.	$179,900	Airbnb cash on cash: 1.34% Traditional cash on cash: 6.94% Airbnb Rental Income: $887 Traditional Rental Income: $1508 Airbnb ROI: 1.34% Traditional ROI: 6.94%
501 Pemberton Place Picayune, MS Our brand new "Preston" is now complete in Heritage Oaks. Experience modern living in a co...	3 beds \| 2 baths \| 1,900 sq.ft.	$372,900	Airbnb cash on cash: 0.17% Traditional cash on cash: 4.84% Airbnb Rental Income: $887 Traditional Rental Income: $2183 Airbnb ROI: 0.17% Traditional ROI: 4.84%
11192 Willie Lee Road Picayune, MS Charming 3 Bedroom home on 7.5 acres with heated pool & handicap accessible features.Welco...	3 beds \| 2 baths \| 2,000 sq.ft.	$370,000	Airbnb cash on cash: -0.05% Traditional cash on cash: 3.14% Airbnb Rental Income: $887 Traditional Rental Income: $1658 Airbnb ROI: -0.05% Traditional ROI: 3.14%
202 N. Boley Dr. Picayune, MS Spacious home with a good sized fenced yard inside City Limits. This home offers a BRAND N...	4 beds \| 3 baths \| 2,787 sq.ft.	$305,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.49% Airbnb Rental Income: $null Traditional Rental Income: $2890 Airbnb ROI: N/A Traditional ROI: 8.49%
138 Essex Court Picayune, MS If you've been waiting for space, charm, and something that doesn't look like every other ...	4 beds \| 2 baths \| 2,008 sq.ft.	$245,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.1% Airbnb Rental Income: $null Traditional Rental Income: $2291 Airbnb ROI: N/A Traditional ROI: 8.1%
39 Cambridge Circle Picayune, MS *REDUCED TO $218,100*** Welcome to this charming 3 bedroom, 2 bath home nestled on 1 c...	3 beds \| 2 baths \| 1,246 sq.ft.	$218,100	Airbnb cash on cash: 1.1% Traditional cash on cash: 7.12% Airbnb Rental Income: $887 Traditional Rental Income: $1792 Airbnb ROI: 1.1% Traditional ROI: 7.12%
11080 Road 231 Picayune, MS This stunning residence, situated on 3 APPX acres, has been newly listed. Property boasts ...	3 beds \| 2 baths \| 2,402 sq.ft.	$499,000	Airbnb cash on cash: -0.21% Traditional cash on cash: 3.46% Airbnb Rental Income: $887 Traditional Rental Income: $2262 Airbnb ROI: -0.21% Traditional ROI: 3.46%
200 N Steele Avenue Picayune, MS Located at 200 N Steele Ave, this charming, totally renovated home (2021) is perfect for f...	3 beds \| 2 baths \| 1,850 sq.ft.	$216,900	Airbnb cash on cash: 0.49% Traditional cash on cash: 9.24% Airbnb Rental Income: $887 Traditional Rental Income: $2347 Airbnb ROI: 0.49% Traditional ROI: 9.24%
307 S. STEELE AVE Picayune, MS Charming 4-Bedroom Home Close to Town! Welcome to this well-maintained 4-bedroom, 2-bath h...	4 beds \| 2 baths \| 1,542 sq.ft.	$199,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.09% Airbnb Rental Income: $null Traditional Rental Income: $1900 Airbnb ROI: N/A Traditional ROI: 8.09%
116 Monk Mitchell Road Picayune, MS Spacious 3-bedroom, 3-bath home nestled on 21.75 beautiful acres featuring a mix of mature...	3 beds \| 4 baths \| 3,681 sq.ft.	$500,000	Airbnb cash on cash: -0.58% Traditional cash on cash: 4.37% Airbnb Rental Income: $887 Traditional Rental Income: $2863 Airbnb ROI: -0.58% Traditional ROI: 4.37%

Real Estate investment in Picayune, MS

There are 77 properties for sale in the city of Picayune . The median list price in Picayune is $245,000 and the average price per square foot is $119. In December 2025, the average monthly cash on cash return in Picayune is 7.00%. The average monthly rental income in Picayune is $2,025.

Picayune, MS Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 77 investment properties available for sale in Picayune.

In 2025, the best neighborhood to buy investment property is Picayune.

The ROI for Short-Term is higher than the Long-Term in Picayune with average rental income of $887.

Your search for investment property begins and ends here

Investment Property for Sale in Picayune, MS

526 Country Club Drive

Picayune, MS

3 beds | 2 baths | 1,882 sq.ft.

$219,900

Airbnb cash on cash: 0.48%

Traditional cash on cash: 7.96%

Airbnb Rental Income: $887

Traditional Rental Income: $2107

Airbnb ROI: 0.48%

Traditional ROI: 7.96%

8 Jennie Lane

Picayune, MS

4 beds | 3 baths | 2,757 sq.ft.

$429,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.66%

Airbnb Rental Income: $null

Traditional Rental Income: $2691

Airbnb ROI: N/A

Traditional ROI: 4.66%

435 Millbrook Parkway

Picayune, MS

3 beds | 2 baths | 2,036 sq.ft.

$254,000

Airbnb cash on cash: 0.4%

Traditional cash on cash: 7.28%

Airbnb Rental Income: $887

Traditional Rental Income: $2201

Airbnb ROI: 0.4%

Traditional ROI: 7.28%

11 Rosewood Dr.

Picayune, MS

4 beds | 2 baths | 1,804 sq.ft.

$259,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.77%

Airbnb Rental Income: $null

Traditional Rental Income: $2196

Airbnb ROI: N/A

Traditional ROI: 6.77%

319 Dozier St

Picayune, MS

3 beds | 2 baths | 1,485 sq.ft.

$175,000

Airbnb cash on cash: 0.94%

Traditional cash on cash: 8.54%

Airbnb Rental Income: $887

Traditional Rental Income: $1816

Airbnb ROI: 0.94%

Traditional ROI: 8.54%

820 Mitchell St.

Picayune, MS

3 beds | 2 baths | N/A

$208,900

Airbnb cash on cash: 0.51%

Traditional cash on cash: 7.14%

Airbnb Rental Income: $887

Traditional Rental Income: $1864

Airbnb ROI: 0.51%

Traditional ROI: 7.14%

1404 Neal Rd

Picayune, MS

3 beds | 3 baths | 3,047 sq.ft.

$393,000

Airbnb cash on cash: -0.56%

Traditional cash on cash: 5.06%

Airbnb Rental Income: $887

Traditional Rental Income: $2621

Airbnb ROI: -0.56%

Traditional ROI: 5.06%

628 Telly Rd

Picayune, MS

3 beds | 2 baths | 1,750 sq.ft.

$234,900

Airbnb cash on cash: 0.25%

Traditional cash on cash: 6.38%

Airbnb Rental Income: $887

Traditional Rental Income: $1911

Airbnb ROI: 0.25%