Real Estate Investment Properties for Sale in Brookline, MO

Looking for investment property in Brookline, MO with high ROI ?

Explore a variety of short-term homes & houses in Brookline, MO. Invest wisely with VRBO & Brookline, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Brookline, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1755 N Boxwood Dr Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 2 baths \| 1,454 sq.ft.	$261,995	Airbnb cash on cash: 1.7% Traditional cash on cash: 10.41% Airbnb Rental Income: $1250 Traditional Rental Income: $3006 Airbnb ROI: 1.7% Traditional ROI: 10.41%
1763 N Boxwood Dr Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 2 baths \| 2,059 sq.ft.	$302,995	Airbnb cash on cash: 3.68% Traditional cash on cash: 7.28% Airbnb Rental Income: $2065 Traditional Rental Income: $2559 Airbnb ROI: 3.68% Traditional ROI: 7.28%
Ashley Plan Brookline, MO Ashley Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 2,179 sq.ft.	$377,500	Airbnb cash on cash: 0.09% Traditional cash on cash: 3.65% Airbnb Rental Income: $1250 Traditional Rental Income: $2112 Airbnb ROI: 0.09% Traditional ROI: 3.65%
Shelby Basement Plan Brookline, MO Shelby Basement Plan, Brookline, MO 65619 \| Single Family Residential	5 beds \| 3 baths \| 3,625 sq.ft.	$482,500	Airbnb cash on cash: N/A Traditional cash on cash: 3.85% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 3.85%
Kylie Plan Brookline, MO Kylie Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,490 sq.ft.	$297,500	Airbnb cash on cash: 0.64% Traditional cash on cash: 4.44% Airbnb Rental Income: $1250 Traditional Rental Income: $1917 Airbnb ROI: 0.64% Traditional ROI: 4.44%
Meadow Basement Plan Brookline, MO Meadow Basement Plan, Brookline, MO 65619 \| Single Family Residential	5 beds \| 3 baths \| 3,554 sq.ft.	$462,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.1% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 4.1%
Meadow Plan Brookline, MO Meadow Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,667 sq.ft.	$322,500	Airbnb cash on cash: 0.44% Traditional cash on cash: 4.1% Airbnb Rental Income: $1250 Traditional Rental Income: $1965 Airbnb ROI: 0.44% Traditional ROI: 4.1%
Brody Plan Brookline, MO Brody Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 2,005 sq.ft.	$372,500	Airbnb cash on cash: 2.06% Traditional cash on cash: 3.73% Airbnb Rental Income: $2065 Traditional Rental Income: $2116 Airbnb ROI: 2.06% Traditional ROI: 3.73%
Emerson Plan Brookline, MO Emerson Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,469 sq.ft.	$292,500	Airbnb cash on cash: 0.68% Traditional cash on cash: 4.31% Airbnb Rental Income: $1250 Traditional Rental Income: $1851 Airbnb ROI: 0.68% Traditional ROI: 4.31%
Indigo Plan Brookline, MO Indigo Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 2,502 sq.ft.	$417,500	Airbnb cash on cash: -0.1% Traditional cash on cash: 3.14% Airbnb Rental Income: $1250 Traditional Rental Income: $2120 Airbnb ROI: -0.1% Traditional ROI: 3.14%
Skylar Basement Plan Brookline, MO Skylar Basement Plan, Brookline, MO 65619 \| Single Family Residential	5 beds \| 3 baths \| 3,090 sq.ft.	$417,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.75% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 4.75%
Shelby Plan Brookline, MO Shelby Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 1,845 sq.ft.	$352,500	Airbnb cash on cash: 2.29% Traditional cash on cash: 3.89% Airbnb Rental Income: $2065 Traditional Rental Income: $2064 Airbnb ROI: 2.29% Traditional ROI: 3.89%
Bonnie Plan Brookline, MO Bonnie Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,651 sq.ft.	$302,500	Airbnb cash on cash: 0.59% Traditional cash on cash: 4.52% Airbnb Rental Income: $1250 Traditional Rental Income: $1971 Airbnb ROI: 0.59% Traditional ROI: 4.52%
Erica Plan Brookline, MO Erica Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,622 sq.ft.	$322,500	Airbnb cash on cash: 0.44% Traditional cash on cash: 4% Airbnb Rental Income: $1250 Traditional Rental Income: $1934 Airbnb ROI: 0.44% Traditional ROI: 4%
Skylar Plan Brookline, MO Skylar Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 1,597 sq.ft.	$322,500	Airbnb cash on cash: 2.68% Traditional cash on cash: 4.21% Airbnb Rental Income: $2065 Traditional Rental Income: $1996 Airbnb ROI: 2.68% Traditional ROI: 4.21%
Ashland Plan Brookline, MO Ashland Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,480 sq.ft.	$292,500	Airbnb cash on cash: 0.68% Traditional cash on cash: 4.31% Airbnb Rental Income: $1250 Traditional Rental Income: $1851 Airbnb ROI: 0.68% Traditional ROI: 4.31%
1750 3-Car Plan Brookline, MO 1750 3-Car Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,752 sq.ft.	$347,087	Airbnb cash on cash: 0.37% Traditional cash on cash: 3.82% Airbnb Rental Income: $1250 Traditional Rental Income: $1979 Airbnb ROI: 0.37% Traditional ROI: 3.82%
1950 Plan Brookline, MO	3 beds \| 2 baths \| 1,950 sq.ft.	$368,188	Airbnb cash on cash: 0.25% Traditional cash on cash: 3.67% Airbnb Rental Income: $1250 Traditional Rental Income: $2028 Airbnb ROI: 0.25% Traditional ROI: 3.67%
Dayton Plan Brookline, MO	4 beds \| 2 baths \| 1,746 sq.ft.	$285,995	Airbnb cash on cash: 3.38% Traditional cash on cash: 5.51% Airbnb Rental Income: $2065 Traditional Rental Income: $2106 Airbnb ROI: 3.38% Traditional ROI: 5.51%
Mesa w/ Basement Plan Brookline, MO Mesa w/ Basement Plan, Brookline, MO 65619 \| Single Family Residential	5 beds \| 3 baths \| 3,294 sq.ft.	$382,995	Airbnb cash on cash: N/A Traditional cash on cash: 5.43% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 5.43%
Charleston w/ Basement Plan Brookline, MO	5 beds \| 3 baths \| 3,040 sq.ft.	$361,995	Airbnb cash on cash: N/A Traditional cash on cash: 6.01% Airbnb Rental Income: $null Traditional Rental Income: $2801 Airbnb ROI: N/A Traditional ROI: 6.01%
1758 N Boxwood Dr Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 2 baths \| 1,951 sq.ft.	$297,995	Airbnb cash on cash: 3.07% Traditional cash on cash: 6.48% Airbnb Rental Income: $2065 Traditional Rental Income: $2490 Airbnb ROI: 3.07% Traditional ROI: 6.48%
1750 N Boxwood Dr Brookline, MO Welcome to The Dayton - a thoughtfully designed two-story home perfect for modern living. ...	4 beds \| 2 baths \| 1,746 sq.ft.	$286,995	Airbnb cash on cash: 3.26% Traditional cash on cash: 6.24% Airbnb Rental Income: $2065 Traditional Rental Income: $2338 Airbnb ROI: 3.26% Traditional ROI: 6.24%
1742 N Boxwood Dr Brookline, MO This stunning 3-bedroom, 2-bathroom home spanning 1,550 square feet features an open conce...	3 beds \| 2 baths \| 1,520 sq.ft.	$274,995	Airbnb cash on cash: 1.6% Traditional cash on cash: 7% Airbnb Rental Income: $1250 Traditional Rental Income: $2254 Airbnb ROI: 1.6% Traditional ROI: 7%
Bonnie Basement Plan Brookline, MO Bonnie Basement Plan, Brookline, MO 65619 \| Single Family Residential	5 beds \| 3 baths \| 3,196 sq.ft.	$397,500	Airbnb cash on cash: N/A Traditional cash on cash: 5.25% Airbnb Rental Income: $null Traditional Rental Income: $2814 Airbnb ROI: N/A Traditional ROI: 5.25%
Charlotte Plan Brookline, MO Charlotte Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 2,465 sq.ft.	$397,500	Airbnb cash on cash: 1.81% Traditional cash on cash: 3.81% Airbnb Rental Income: $2065 Traditional Rental Income: $2278 Airbnb ROI: 1.81% Traditional ROI: 3.81%
Claire Plan Brookline, MO Claire Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 2,321 sq.ft.	$347,500	Airbnb cash on cash: 2.35% Traditional cash on cash: 4.57% Airbnb Rental Income: $2065 Traditional Rental Income: $2257 Airbnb ROI: 2.35% Traditional ROI: 4.57%
1754 N Poplar Way Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 2 baths \| 1,951 sq.ft.	$304,365	Airbnb cash on cash: 2.95% Traditional cash on cash: 6.37% Airbnb Rental Income: $2065 Traditional Rental Income: $2511 Airbnb ROI: 2.95% Traditional ROI: 6.37%
1739 N Knollwood Ave Brookline, MO Introducing a 5-bed, 3-bath home with a walkout basement, making it a versatile haven span...	5 beds \| 3 baths \| 3,053 sq.ft.	$397,315	Airbnb cash on cash: N/A Traditional cash on cash: 5.8% Airbnb Rental Income: $null Traditional Rental Income: $3015 Airbnb ROI: N/A Traditional ROI: 5.8%
1710 N Boxwood Dr Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 2 baths \| 2,059 sq.ft.	$309,570	Airbnb cash on cash: 3.04% Traditional cash on cash: 7.44% Airbnb Rental Income: $2065 Traditional Rental Income: $2812 Airbnb ROI: 3.04% Traditional ROI: 7.44%
1718 N Boxwood Dr Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 2 baths \| 1,428 sq.ft.	$270,390	Airbnb cash on cash: 0.95% Traditional cash on cash: 6.6% Airbnb Rental Income: $1250 Traditional Rental Income: $2294 Airbnb ROI: 0.95% Traditional ROI: 6.6%
1726 N Boxwood Dr Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 2 baths \| 2,059 sq.ft.	$310,995	Airbnb cash on cash: 3.02% Traditional cash on cash: 7.33% Airbnb Rental Income: $2065 Traditional Rental Income: $2793 Airbnb ROI: 3.02% Traditional ROI: 7.33%
Oakwood Plan Brookline, MO Oakwood Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,454 sq.ft.	$259,995	Airbnb cash on cash: 1.14% Traditional cash on cash: 5.39% Airbnb Rental Income: $1250 Traditional Rental Income: $1896 Airbnb ROI: 1.14% Traditional ROI: 5.39%
2200-3C Plan Brookline, MO 2200-3C Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 2,200 sq.ft.	$386,284	Airbnb cash on cash: 0.14% Traditional cash on cash: 3.85% Airbnb Rental Income: $1250 Traditional Rental Income: $2192 Airbnb ROI: 0.14% Traditional ROI: 3.85%
2000-3C Plan Brookline, MO 2000-3C Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 2,000 sq.ft.	$367,792	Airbnb cash on cash: 0.25% Traditional cash on cash: 4% Airbnb Rental Income: $1250 Traditional Rental Income: $2143 Airbnb ROI: 0.25% Traditional ROI: 4%
1800-3C Plan Brookline, MO 1800-3C Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,800 sq.ft.	$348,658	Airbnb cash on cash: 0.36% Traditional cash on cash: 4.07% Airbnb Rental Income: $1250 Traditional Rental Income: $2066 Airbnb ROI: 0.36% Traditional ROI: 4.07%
1783 N Knollwood Ave Brookline, MO This modern home boasts 5 bedrooms, 3 bathrooms, and spans 3040 sq ft. Its open concept la...	5 beds \| 3 baths \| 2,622 sq.ft.	$364,995	Airbnb cash on cash: N/A Traditional cash on cash: 6.45% Airbnb Rental Income: $null Traditional Rental Income: $2908 Airbnb ROI: N/A Traditional ROI: 6.45%
2833 N York Ave Brookline, MO Welcome home to 2833 N York Ave in Brookline! This beautifully remodeled 3-bedroom, 2-bath...	3 beds \| 2 baths \| 1,604 sq.ft.	$230,000	Airbnb cash on cash: 2.27% Traditional cash on cash: 8.39% Airbnb Rental Income: $1250 Traditional Rental Income: $2185 Airbnb ROI: 2.27% Traditional ROI: 8.39%
5725 S Farm Rd 131 Brookline, MO Welcome to your own private Ozarks retreat! Nestled on approximately 6.7 picturesque acres...	4 beds \| 3 baths \| 4,000 sq.ft.	$650,000	Airbnb cash on cash: 0.81% Traditional cash on cash: 3.98% Airbnb Rental Income: $2065 Traditional Rental Income: $3603 Airbnb ROI: 0.81% Traditional ROI: 3.98%
2665 W Old Limey Road Brookline, MO Welcome to Your Private Missouri Countryside Estate! 2665 W Old Limey Road, Brookline, MOE...	5 beds \| 5 baths \| 3,903 sq.ft.	$898,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.73% Airbnb Rental Income: $null Traditional Rental Income: $3777 Airbnb ROI: N/A Traditional ROI: 2.73%

Real Estate investment in Brookline, MO

There are 48 properties for sale in the city of Brookline . The median list price in Brookline is $1,332,000 and the average price per square foot is $410. In August 2026, the average monthly cash on cash return in Brookline is 5.00%. The average monthly rental income in Brookline is $2,297.

Brookline, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 48 investment properties available for sale in Brookline.

In 2026, the best neighborhood to buy investment property is Brookline.

The ROI for Long-Term is higher than the Short-Term in Brookline with average rental income of $2,297.

Your search for investment property begins and ends here

Investment Property for Sale in Brookline, MO

1755 N Boxwood Dr

Brookline, MO

3 beds | 2 baths | 1,454 sq.ft.

$261,995

Airbnb cash on cash: 1.7%

Traditional cash on cash: 10.41%

Airbnb Rental Income: $1250

Traditional Rental Income: $3006

Airbnb ROI: 1.7%

Traditional ROI: 10.41%

1763 N Boxwood Dr

Brookline, MO

4 beds | 2 baths | 2,059 sq.ft.

$302,995

Airbnb cash on cash: 3.68%

Traditional cash on cash: 7.28%

Airbnb Rental Income: $2065

Traditional Rental Income: $2559

Airbnb ROI: 3.68%

Traditional ROI: 7.28%

Ashley Plan

Brookline, MO

3 beds | 2 baths | 2,179 sq.ft.

$377,500

Airbnb cash on cash: 0.09%

Traditional cash on cash: 3.65%

Airbnb Rental Income: $1250

Traditional Rental Income: $2112

Airbnb ROI: 0.09%

Traditional ROI: 3.65%

Shelby Basement Plan

Brookline, MO

5 beds | 3 baths | 3,625 sq.ft.

$482,500

Airbnb cash on cash: N/A

Traditional cash on cash: 3.85%

Airbnb Rental Income: $null

Traditional Rental Income: $2750

Airbnb ROI: N/A

Traditional ROI: 3.85%

Kylie Plan

Brookline, MO

3 beds | 2 baths | 1,490 sq.ft.

$297,500

Airbnb cash on cash: 0.64%

Traditional cash on cash: 4.44%

Airbnb Rental Income: $1250

Traditional Rental Income: $1917

Airbnb ROI: 0.64%

Traditional ROI: 4.44%

Meadow Basement Plan

Brookline, MO

5 beds | 3 baths | 3,554 sq.ft.

$462,500

Airbnb cash on cash: N/A

Traditional cash on cash: 4.1%

Airbnb Rental Income: $null

Traditional Rental Income: $2750

Airbnb ROI: N/A

Traditional ROI: 4.1%

Meadow Plan

Brookline, MO

3 beds | 2 baths | 1,667 sq.ft.

$322,500

Airbnb cash on cash: 0.44%

Traditional cash on cash: 4.1%

Airbnb Rental Income: $1250

Traditional Rental Income: $1965

Airbnb ROI: 0.44%

Traditional ROI: 4.1%

Brody Plan

Brookline, MO

4 beds | 2 baths | 2,005 sq.ft.

$372,500

Airbnb cash on cash: 2.06%

Traditional cash on cash: 3.73%

Airbnb Rental Income: $2065

Traditional Rental Income: $2116

Airbnb ROI: 2.06%