Real Estate Investment Properties for Sale in Brookline, MO

Looking for investment property in Brookline, MO with high ROI ?

Explore a variety of short-term homes & houses in Brookline, MO. Invest wisely with VRBO & Brookline, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Brookline, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2665 W Old Limey Road Brookline, MO Welcome to Your Private Missouri Countryside Estate! 2665 W Old Limey Road, Brookline, MOE...	5 beds \| 5 baths \| 3,903 sq.ft.	$898,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.73% Airbnb Rental Income: $null Traditional Rental Income: $3777 Airbnb ROI: N/A Traditional ROI: 2.73%
4074 E Ashwood Court Brookline, MO Introducing a 5-bed, 3-bath home with a walkout basement, making it a versatile haven span...	5 beds \| 3 baths \| 3,053 sq.ft.	$393,995	Airbnb cash on cash: N/A Traditional cash on cash: 6.07% Airbnb Rental Income: $null Traditional Rental Income: $3089 Airbnb ROI: N/A Traditional ROI: 6.07%
1755 N Boxwood Drive Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 2 baths \| 1,428 sq.ft.	$254,995	Airbnb cash on cash: 2.07% Traditional cash on cash: 10.72% Airbnb Rental Income: $1335 Traditional Rental Income: $3006 Airbnb ROI: 2.07% Traditional ROI: 10.72%
1763 N Boxwood Drive Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$302,995	Airbnb cash on cash: 1.7% Traditional cash on cash: 7.28% Airbnb Rental Income: $1387 Traditional Rental Income: $2559 Airbnb ROI: 1.7% Traditional ROI: 7.28%
Ashley Plan Brookline, MO	3 beds \| 2 baths \| 2,179 sq.ft.	$385,000	Airbnb cash on cash: 0.25% Traditional cash on cash: 3.54% Airbnb Rental Income: $1335 Traditional Rental Income: $2112 Airbnb ROI: 0.25% Traditional ROI: 3.54%
Shelby Basement Plan Brookline, MO	5 beds \| 3 baths \| 3,750 sq.ft.	$480,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.88% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 3.88%
Kylie Plan Brookline, MO	3 beds \| 2 baths \| 1,490 sq.ft.	$315,000	Airbnb cash on cash: 0.73% Traditional cash on cash: 4.08% Airbnb Rental Income: $1335 Traditional Rental Income: $1917 Airbnb ROI: 0.73% Traditional ROI: 4.08%
Meadow Basement Plan Brookline, MO	5 beds \| 3 baths \| 3,554 sq.ft.	$475,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.94% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 3.94%
5241 S Morgan Ave Brookline, MO 5241 S Morgan Ave, Brookline, MO 65619 \| Single Family Residential	4 beds \| 3 baths \| 1,753 sq.ft.	$359,948	Airbnb cash on cash: 0.54% Traditional cash on cash: 4.46% Airbnb Rental Income: $1387 Traditional Rental Income: $2291 Airbnb ROI: 0.54% Traditional ROI: 4.46%
Meadow Plan Brookline, MO	3 beds \| 2 baths \| 1,667 sq.ft.	$335,000	Airbnb cash on cash: 0.57% Traditional cash on cash: 3.88% Airbnb Rental Income: $1335 Traditional Rental Income: $1965 Airbnb ROI: 0.57% Traditional ROI: 3.88%
Brody Plan Brookline, MO	4 beds \| 2 baths \| 2,005 sq.ft.	$375,000	Airbnb cash on cash: 0.43% Traditional cash on cash: 3.7% Airbnb Rental Income: $1387 Traditional Rental Income: $2116 Airbnb ROI: 0.43% Traditional ROI: 3.7%
Emerson Plan Brookline, MO	3 beds \| 2 baths \| 1,469 sq.ft.	$310,000	Airbnb cash on cash: 0.77% Traditional cash on cash: 3.95% Airbnb Rental Income: $1335 Traditional Rental Income: $1851 Airbnb ROI: 0.77% Traditional ROI: 3.95%
Indigo Plan Brookline, MO	3 beds \| 2 baths \| 2,502 sq.ft.	$430,000	Airbnb cash on cash: 0.02% Traditional cash on cash: 2.99% Airbnb Rental Income: $1335 Traditional Rental Income: $2120 Airbnb ROI: 0.02% Traditional ROI: 2.99%
Skylar Basement Plan Brookline, MO	5 beds \| 3 baths \| 3,194 sq.ft.	$430,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.55% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 4.55%
Shelby Plan Brookline, MO	4 beds \| 2 baths \| 1,845 sq.ft.	$365,000	Airbnb cash on cash: 0.49% Traditional cash on cash: 3.7% Airbnb Rental Income: $1387 Traditional Rental Income: $2064 Airbnb ROI: 0.49% Traditional ROI: 3.7%
Bonnie Plan Brookline, MO	3 beds \| 2 baths \| 1,651 sq.ft.	$320,000	Airbnb cash on cash: 0.69% Traditional cash on cash: 4.17% Airbnb Rental Income: $1335 Traditional Rental Income: $1971 Airbnb ROI: 0.69% Traditional ROI: 4.17%
Erica Plan Brookline, MO	3 beds \| 2 baths \| 1,622 sq.ft.	$335,000	Airbnb cash on cash: 0.57% Traditional cash on cash: 3.78% Airbnb Rental Income: $1335 Traditional Rental Income: $1934 Airbnb ROI: 0.57% Traditional ROI: 3.78%
Skylar Plan Brookline, MO	4 beds \| 2 baths \| 1,597 sq.ft.	$335,000	Airbnb cash on cash: 0.71% Traditional cash on cash: 3.98% Airbnb Rental Income: $1387 Traditional Rental Income: $1996 Airbnb ROI: 0.71% Traditional ROI: 3.98%
Ashland Plan Brookline, MO	3 beds \| 2 baths \| 1,480 sq.ft.	$305,000	Airbnb cash on cash: 0.82% Traditional cash on cash: 4.05% Airbnb Rental Income: $1335 Traditional Rental Income: $1851 Airbnb ROI: 0.82% Traditional ROI: 4.05%
1722 N Hawthorne Place Brookline, MO The Aspen floor plan offers four spacious bedrooms and a world of flexibility to fit your ...	4 beds \| 3 baths \| 2,120 sq.ft.	$336,995	Airbnb cash on cash: 0.71% Traditional cash on cash: 5.39% Airbnb Rental Income: $1387 Traditional Rental Income: $2449 Airbnb ROI: 0.71% Traditional ROI: 5.39%
1750 3-Car Plan Brookline, MO 1750 3-Car Plan, Brookline, MO 65619 \| Single Family Residential	3 beds \| 2 baths \| 1,752 sq.ft.	$347,087	Airbnb cash on cash: 0.58% Traditional cash on cash: 3.82% Airbnb Rental Income: $1335 Traditional Rental Income: $1979 Airbnb ROI: 0.58% Traditional ROI: 3.82%
1950 Plan Brookline, MO	3 beds \| 2 baths \| 1,950 sq.ft.	$366,170	Airbnb cash on cash: 0.45% Traditional cash on cash: 3.67% Airbnb Rental Income: $1335 Traditional Rental Income: $2028 Airbnb ROI: 0.45% Traditional ROI: 3.67%
Dayton Plan Brookline, MO	4 beds \| 2 baths \| 1,746 sq.ft.	$285,995	Airbnb cash on cash: 1.28% Traditional cash on cash: 5.51% Airbnb Rental Income: $1387 Traditional Rental Income: $2106 Airbnb ROI: 1.28% Traditional ROI: 5.51%
Mesa w/ Basement Plan Brookline, MO	5 beds \| 3 baths \| 3,416 sq.ft.	$382,995	Airbnb cash on cash: N/A Traditional cash on cash: 5.43% Airbnb Rental Income: $null Traditional Rental Income: $2750 Airbnb ROI: N/A Traditional ROI: 5.43%
Charleston w/ Basement Plan Brookline, MO	5 beds \| 3 baths \| 3,040 sq.ft.	$361,995	Airbnb cash on cash: N/A Traditional cash on cash: 6.01% Airbnb Rental Income: $null Traditional Rental Income: $2801 Airbnb ROI: N/A Traditional ROI: 6.01%
1758 N Boxwood Drive Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 3 baths \| 1,951 sq.ft.	$297,995	Airbnb cash on cash: 1.05% Traditional cash on cash: 6.48% Airbnb Rental Income: $1387 Traditional Rental Income: $2490 Airbnb ROI: 1.05% Traditional ROI: 6.48%
1750 N Boxwood Drive Brookline, MO Welcome to The Dayton - a thoughtfully designed two-story home perfect for modern living. ...	4 beds \| 3 baths \| 1,746 sq.ft.	$286,995	Airbnb cash on cash: 1.17% Traditional cash on cash: 6.24% Airbnb Rental Income: $1387 Traditional Rental Income: $2338 Airbnb ROI: 1.17% Traditional ROI: 6.24%
1742 N Boxwood Drive Brookline, MO This stunning 3-bedroom, 2-bathroom home spanning 1,550 square feet features an open conce...	3 beds \| 2 baths \| 1,520 sq.ft.	$274,995	Airbnb cash on cash: 1.87% Traditional cash on cash: 7% Airbnb Rental Income: $1335 Traditional Rental Income: $2254 Airbnb ROI: 1.87% Traditional ROI: 7%
Bonnie Basement Plan Brookline, MO Bonnie Basement Plan, Brookline, MO 65619 \| Single Family Residential	5 beds \| 3 baths \| 3,296 sq.ft.	$395,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.3% Airbnb Rental Income: $null Traditional Rental Income: $2814 Airbnb ROI: N/A Traditional ROI: 5.3%
Charlotte Plan Brookline, MO Charlotte Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 2,565 sq.ft.	$385,000	Airbnb cash on cash: 0.37% Traditional cash on cash: 4% Airbnb Rental Income: $1387 Traditional Rental Income: $2278 Airbnb ROI: 0.37% Traditional ROI: 4%
Claire Plan Brookline, MO Claire Plan, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 2,421 sq.ft.	$345,000	Airbnb cash on cash: 0.63% Traditional cash on cash: 4.62% Airbnb Rental Income: $1387 Traditional Rental Income: $2257 Airbnb ROI: 0.63% Traditional ROI: 4.62%
1754 N Poplar Way Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 3 baths \| 1,951 sq.ft.	$304,365	Airbnb cash on cash: 0.98% Traditional cash on cash: 6.37% Airbnb Rental Income: $1387 Traditional Rental Income: $2511 Airbnb ROI: 0.98% Traditional ROI: 6.37%
5727 S State Highway FF Brookline, MO 5727 S State Highway FF, Brookline, MO 65619 \| Single Family Residential	4 beds \| 2 baths \| 1,830 sq.ft.	$389,900	Airbnb cash on cash: 0.43% Traditional cash on cash: 3.68% Airbnb Rental Income: $1387 Traditional Rental Income: $2156 Airbnb ROI: 0.43% Traditional ROI: 3.68%
1739 N Knollwood Avenue Brookline, MO Introducing a 5-bed, 3-bath home with a walkout basement, making it a versatile haven span...	5 beds \| 3 baths \| 3,053 sq.ft.	$397,315	Airbnb cash on cash: N/A Traditional cash on cash: 5.8% Airbnb Rental Income: $null Traditional Rental Income: $3015 Airbnb ROI: N/A Traditional ROI: 5.8%
1710 N Boxwood Drive Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$309,570	Airbnb cash on cash: 1.1% Traditional cash on cash: 7.44% Airbnb Rental Income: $1387 Traditional Rental Income: $2812 Airbnb ROI: 1.1% Traditional ROI: 7.44%
1718 N Boxwood Drive Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 3 baths \| 1,428 sq.ft.	$266,390	Airbnb cash on cash: 1.26% Traditional cash on cash: 6.72% Airbnb Rental Income: $1335 Traditional Rental Income: $2294 Airbnb ROI: 1.26% Traditional ROI: 6.72%
1726 N Boxwood Drive Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$310,995	Airbnb cash on cash: 1.09% Traditional cash on cash: 7.33% Airbnb Rental Income: $1387 Traditional Rental Income: $2793 Airbnb ROI: 1.09% Traditional ROI: 7.33%
5877 S Farm Road 115 Brookline, MO Welcome to 5877 South Farm Road 115--your ideal country retreat! This charming home offers...	3 beds \| 1 baths \| 1,176 sq.ft.	$229,900	Airbnb cash on cash: 2.22% Traditional cash on cash: 6.1% Airbnb Rental Income: $1335 Traditional Rental Income: $1767 Airbnb ROI: 2.22% Traditional ROI: 6.1%
3942 E Fieldcrest Court Brookline, MO Welcome to the Savannah! This stunning 2-story home boasts 4 bedrooms, 2.5 baths, and a sp...	4 beds \| 3 baths \| 2,350 sq.ft.	$339,995	Airbnb cash on cash: 1.47% Traditional cash on cash: 7.95% Airbnb Rental Income: $1387 Traditional Rental Income: $3037 Airbnb ROI: 1.47% Traditional ROI: 7.95%
1746 N Poplar Way Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$327,017	Airbnb cash on cash: 0.73% Traditional cash on cash: 5.99% Airbnb Rental Income: $1387 Traditional Rental Income: $2583 Airbnb ROI: 0.73% Traditional ROI: 5.99%

Real Estate investment in Brookline, MO

There are 42 properties for sale in the city of Brookline . The median list price in Brookline is $1,400,000 and the average price per square foot is $424. In May 2026, the average monthly cash on cash return in Brookline is 5.00%. The average monthly rental income in Brookline is $2,293.

Brookline, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 42 investment properties available for sale in Brookline.

In 2026, the best neighborhood to buy investment property is Brookline.

The ROI for Long-Term is higher than the Short-Term in Brookline with average rental income of $2,293.

Your search for investment property begins and ends here

Investment Property for Sale in Brookline, MO

2665 W Old Limey Road

Brookline, MO

5 beds | 5 baths | 3,903 sq.ft.

$898,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.73%

Airbnb Rental Income: $null

Traditional Rental Income: $3777

Airbnb ROI: N/A

Traditional ROI: 2.73%

4074 E Ashwood Court

Brookline, MO

5 beds | 3 baths | 3,053 sq.ft.

$393,995

Airbnb cash on cash: N/A

Traditional cash on cash: 6.07%

Airbnb Rental Income: $null

Traditional Rental Income: $3089

Airbnb ROI: N/A

Traditional ROI: 6.07%

1755 N Boxwood Drive

Brookline, MO

3 beds | 2 baths | 1,428 sq.ft.

$254,995

Airbnb cash on cash: 2.07%

Traditional cash on cash: 10.72%

Airbnb Rental Income: $1335

Traditional Rental Income: $3006

Airbnb ROI: 2.07%

Traditional ROI: 10.72%

1763 N Boxwood Drive

Brookline, MO

4 beds | 3 baths | 2,059 sq.ft.

$302,995

Airbnb cash on cash: 1.7%

Traditional cash on cash: 7.28%

Airbnb Rental Income: $1387

Traditional Rental Income: $2559

Airbnb ROI: 1.7%

Traditional ROI: 7.28%

Ashley Plan

Brookline, MO

3 beds | 2 baths | 2,179 sq.ft.

$385,000

Airbnb cash on cash: 0.25%

Traditional cash on cash: 3.54%

Airbnb Rental Income: $1335

Traditional Rental Income: $2112

Airbnb ROI: 0.25%

Traditional ROI: 3.54%

Shelby Basement Plan

Brookline, MO

5 beds | 3 baths | 3,750 sq.ft.

$480,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.88%

Airbnb Rental Income: $null

Traditional Rental Income: $2750

Airbnb ROI: N/A

Traditional ROI: 3.88%

Kylie Plan

Brookline, MO

3 beds | 2 baths | 1,490 sq.ft.

$315,000

Airbnb cash on cash: 0.73%

Traditional cash on cash: 4.08%

Airbnb Rental Income: $1335

Traditional Rental Income: $1917

Airbnb ROI: 0.73%

Traditional ROI: 4.08%

Meadow Basement Plan

Brookline, MO

5 beds | 3 baths | 3,554 sq.ft.

$475,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.94%

Airbnb Rental Income: $null

Traditional Rental Income: $2750

Airbnb ROI: N/A