Real Estate Investment Properties for Sale in Defiance, MO

Looking for investment property in Defiance, MO with high ROI ?

Explore a variety of short-term homes & houses in Defiance, MO. Invest wisely with VRBO & Defiance, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

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Investment Property for Sale in Defiance, MO

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Real Estate investment in Defiance, MO

There are 6 properties for sale in the city of Defiance . The median list price in Defiance is $189,000 and the average price per square foot is $148. In February 2026, the average monthly cash on cash return in Defiance is 2.00%. The average monthly rental income in Defiance is $3,046.

Defiance, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 6 investment properties available for sale in Defiance.

In 2026, the best neighborhood to buy investment property is Defiance.

The ROI for Short-Term is higher than the Long-Term in Defiance with average rental income of $N/A.