Real Estate Investment Properties for Sale in Doniphan, MO

Looking for investment property in Doniphan, MO with high ROI ?

Explore a variety of short-term homes & houses in Doniphan, MO. Invest wisely with VRBO & Doniphan, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Doniphan, MO

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4396 State Highway 21 Doniphan, MO Remarkable Home within 5 minutes of Doniphan! This 3,(possibly 4) bedroom, 2 bath home on ...	3 beds \| 2 baths \| 2,064 sq.ft.	$269,900	Airbnb cash on cash: -0.74% Traditional cash on cash: 6.63% Airbnb Rental Income: $477 Traditional Rental Income: $2084 Airbnb ROI: -0.74% Traditional ROI: 6.63%
4795 Ripley K-1 Doniphan, MO MOTIVATED SELLER-----Built in 2024, this beautiful 4-bedroom, 2-bath home offers modern co...	4 beds \| 2 baths \| 1,800 sq.ft.	$274,999	Airbnb cash on cash: 3.83% Traditional cash on cash: 5.87% Airbnb Rental Income: $1965 Traditional Rental Income: $1978 Airbnb ROI: 3.83% Traditional ROI: 5.87%
1901 River Valley Road Doniphan, MO CURRENT RIVER CABIN - RIVERFRONT, 2 ACRES, MINUTES FROM DONIPHAN Experience the beauty of...	3 beds \| 3 baths \| 1,834 sq.ft.	$674,900	Airbnb cash on cash: -1.11% Traditional cash on cash: 2.6% Airbnb Rental Income: $477 Traditional Rental Income: $2540 Airbnb ROI: -1.11% Traditional ROI: 2.6%
81 Southern Comfort Doniphan, MO $575,000; 81 Southern Comfort, Doniphan, MO 63935; Beautiful 3 bedroom 2 bathroom river ca...	3 beds \| 2 baths \| 1,440 sq.ft.	$595,000	Airbnb cash on cash: -0.97% Traditional cash on cash: 1.81% Airbnb Rental Income: $477 Traditional Rental Income: $1750 Airbnb ROI: -0.97% Traditional ROI: 1.81%
249 Trails End Way Doniphan, MO Custom built in 2017 this 2 bedroom 1 bath home has a finished loft bonus room and is buil...	3 beds \| 1 baths \| 1,388 sq.ft.	$219,000	Airbnb cash on cash: -0.81% Traditional cash on cash: 7.03% Airbnb Rental Income: $477 Traditional Rental Income: $1835 Airbnb ROI: -0.81% Traditional ROI: 7.03%
6029 Ripley Rt V Doniphan, MO Breath-taking home on 6.5 acres (m/l) on top of the hill! You have to see this 3067 sq ft ...	3 beds \| 3 baths \| 3,067 sq.ft.	$399,000	Airbnb cash on cash: -1.02% Traditional cash on cash: 5.42% Airbnb Rental Income: $477 Traditional Rental Income: $2619 Airbnb ROI: -1.02% Traditional ROI: 5.42%
64 Trails End Ln Doniphan, MO The Octagon Lodge is a one-of-a-kind retreat located in a gated community on the Current R...	3 beds \| 3 baths \| 2,801 sq.ft.	$425,000	Airbnb cash on cash: -0.95% Traditional cash on cash: 6.9% Airbnb Rental Income: $477 Traditional Rental Income: $3331 Airbnb ROI: -0.95% Traditional ROI: 6.9%
936 Crawdad Lane Doniphan, MO Private 75-Acre Estate with Lake, 3 Homes & borders Government Forest . A private Lakefro...	4 beds \| 2 baths \| 2,997 sq.ft.	$749,900	Airbnb cash on cash: 0.75% Traditional cash on cash: 2.51% Airbnb Rental Income: $1965 Traditional Rental Income: $2677 Airbnb ROI: 0.75% Traditional ROI: 2.51%
1103 Cherry St Doniphan, MO This is the listing that everyone will be talking about. It's a Doniphan landmark. Sitting...	4 beds \| 3 baths \| 6,280 sq.ft.	$349,000	Airbnb cash on cash: 2.56% Traditional cash on cash: 6.56% Airbnb Rental Income: $1965 Traditional Rental Income: $2757 Airbnb ROI: 2.56% Traditional ROI: 6.56%
1300 River Valley Road Doniphan, MO Experience refined riverfront living in this exceptional 4 bedroom, 3 bath contemporary ca...	4 beds \| 3 baths \| 1,768 sq.ft.	$625,000	Airbnb cash on cash: 1.1% Traditional cash on cash: 3.3% Airbnb Rental Income: $1965 Traditional Rental Income: $2732 Airbnb ROI: 1.1% Traditional ROI: 3.3%
1457 Riverway Dr Doniphan, MO Escape to modern luxury in this Riverfront cabin retreat! Welcome to your dream getaway- a...	5 beds \| 2 baths \| 2,480 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $2605 Airbnb ROI: N/A Traditional ROI: 3.86%
607 Wanda Rd Doniphan, MO This beautifully remodeled 3 bedroom, 2 bath home offers a perfect blend of modern comfort...	3 beds \| 2 baths \| 1,444 sq.ft.	$189,500	Airbnb cash on cash: -0.63% Traditional cash on cash: 6.19% Airbnb Rental Income: $477 Traditional Rental Income: $1436 Airbnb ROI: -0.63% Traditional ROI: 6.19%
4375 State Highway 142 east Doniphan, MO Charming 3 Bedroom Brick Home Near Current River! Looking for peaceful country living j...	3 beds \| 2 baths \| 1,956 sq.ft.	$205,500	Airbnb cash on cash: -0.76% Traditional cash on cash: 9.24% Airbnb Rental Income: $477 Traditional Rental Income: $2156 Airbnb ROI: -0.76% Traditional ROI: 9.24%
1008 Barton Rd Doniphan, MO Take a look at this newly remodeled home on the edge of city limits just outside of Doniph...	3 beds \| 2 baths \| 2,324 sq.ft.	$259,500	Airbnb cash on cash: -0.82% Traditional cash on cash: 9.2% Airbnb Rental Income: $477 Traditional Rental Income: $2662 Airbnb ROI: -0.82% Traditional ROI: 9.2%
285 Ripley Z-4 Doniphan, MO Check out this awesome 84 acre +/- property with a home, barn, shop, pond and extra well o...	3 beds \| 1 baths \| 1,160 sq.ft.	$349,500	Airbnb cash on cash: -0.77% Traditional cash on cash: 3.32% Airbnb Rental Income: $477 Traditional Rental Income: $1551 Airbnb ROI: -0.77% Traditional ROI: 3.32%
489 Pumpkin Patch Rd Doniphan, MO Escape to your dream country life! This stunning barndominium on 13 +/- acres just outside...	2 beds \| 1 baths \| 3,600 sq.ft.	$550,000	Airbnb cash on cash: -1.47% Traditional cash on cash: 1.86% Airbnb Rental Income: $241 Traditional Rental Income: $1726 Airbnb ROI: -1.47% Traditional ROI: 1.86%
53 Snapping Turtle Ln Doniphan, MO Freshly remodeled three bed, two bath home just east of Doniphan off Brooks Lane. Sitting ...	3 beds \| 2 baths \| 1,374 sq.ft.	$179,000	Airbnb cash on cash: -0.73% Traditional cash on cash: 7.8% Airbnb Rental Income: $477 Traditional Rental Income: $1662 Airbnb ROI: -0.73% Traditional ROI: 7.8%
39 Oxen Pasture Rd Doniphan, MO HOME FOR SALE IN DONIPHAN, MISSOURI WITH DETACHED SHOP Featuring a very modern and...	4 beds \| 3 baths \| 1,700 sq.ft.	$329,000	Airbnb cash on cash: 2.42% Traditional cash on cash: 3.15% Airbnb Rental Income: $1965 Traditional Rental Income: $1673 Airbnb ROI: 2.42% Traditional ROI: 3.15%
2756 Ripley 142e-20 Doniphan, MO Newly remodeled home comes with kitchen appliances, a partially fenced back yard on a leve...	3 beds \| 1 baths \| 1,034 sq.ft.	$129,900	Airbnb cash on cash: -0.34% Traditional cash on cash: 8.22% Airbnb Rental Income: $477 Traditional Rental Income: $1277 Airbnb ROI: -0.34% Traditional ROI: 8.22%
13 Walleye Ln Doniphan, MO Turn-Key 3BR Log Cabin on the Current River - No Flood Risk - Fully FurnishedBeautifully m...	3 beds \| 1 baths \| 1,200 sq.ft.	$449,000	Airbnb cash on cash: -0.8% Traditional cash on cash: 0.88% Airbnb Rental Income: $477 Traditional Rental Income: $910 Airbnb ROI: -0.8% Traditional ROI: 0.88%
000 Ff-1 Doniphan, MO 000 Ff-1, Doniphan, MO 63935 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$49,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.54% Airbnb Rental Income: $null Traditional Rental Income: $727 Airbnb ROI: N/A Traditional ROI: 10.54%
1585 River Valley Rd Doniphan, MO 1585 River Valley Rd, Doniphan, MO 63935 \| Single Family Residential	4 beds \| 2 baths \| 1,800 sq.ft.	$900,000	Airbnb cash on cash: -0.35% Traditional cash on cash: -0.04% Airbnb Rental Income: $1965 Traditional Rental Income: $1706 Airbnb ROI: -0.35% Traditional ROI: -0.04%
1901 River Valley Rd Doniphan, MO 1901 River Valley Rd, Doniphan, MO 63935 \| Single Family Residential	3 beds \| 2 baths \| 1,834 sq.ft.	$674,900	Airbnb cash on cash: -1.78% Traditional cash on cash: 0.81% Airbnb Rental Income: $477 Traditional Rental Income: $1840 Airbnb ROI: -1.78% Traditional ROI: 0.81%
1300 River Valley Rd Doniphan, MO	4 beds \| 3 baths \| 1,768 sq.ft.	$625,000	Airbnb cash on cash: 0.36% Traditional cash on cash: 0.8% Airbnb Rental Income: $1965 Traditional Rental Income: $1706 Airbnb ROI: 0.36% Traditional ROI: 0.8%
563 Bridge St Doniphan, MO 563 Bridge St, Doniphan, MO 63935 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$65,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.82% Airbnb Rental Income: $null Traditional Rental Income: $727 Airbnb ROI: N/A Traditional ROI: 7.82%
0 142e-2a Doniphan, MO 0 142e-2a, Doniphan, MO 63935 \| Single Family Residential	3 beds \| 1 baths \| 1,434 sq.ft.	$849,000	Airbnb cash on cash: -1.82% Traditional cash on cash: -0.56% Airbnb Rental Income: $477 Traditional Rental Income: $1202 Airbnb ROI: -1.82% Traditional ROI: -0.56%
227 Walleye LN Doniphan, MO 227 Walleye LN, Doniphan, MO 63935 \| Single Family Residential	2 beds \| N/A baths \| 1,432 sq.ft.	$299,990	Airbnb cash on cash: -2.25% Traditional cash on cash: 1.86% Airbnb Rental Income: $241 Traditional Rental Income: $1171 Airbnb ROI: -2.25% Traditional ROI: 1.86%
243 Big Pine Rd Doniphan, MO Escape to the peace and privacy of country living on 3.49 +/- acres surrounded by woods an...	3 beds \| 2 baths \| 1,860 sq.ft.	$339,900	Airbnb cash on cash: -0.96% Traditional cash on cash: 4.07% Airbnb Rental Income: $477 Traditional Rental Income: $1815 Airbnb ROI: -0.96% Traditional ROI: 4.07%
1067 Forest Road 4811 Doniphan, MO 1067 Forest Road 4811, Doniphan, MO 63935 \| Single Family Residential	4 beds \| 3 baths \| 2,150 sq.ft.	$769,500	Airbnb cash on cash: -0.07% Traditional cash on cash: 0.88% Airbnb Rental Income: $1965 Traditional Rental Income: $2132 Airbnb ROI: -0.07% Traditional ROI: 0.88%
0 Corner 160 And 21 S Doniphan, MO 0 Corner 160 And 21 S, Doniphan, MO 63935 \| Other	N/A beds \| N/A baths \| N/A	$45,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.95% Airbnb Rental Income: $null Traditional Rental Income: $736 Airbnb ROI: N/A Traditional ROI: 11.95%
21 Hwy 21 N Doniphan, MO 21 Hwy 21 N, Doniphan, MO 63935 \| Other	N/A beds \| N/A baths \| N/A	$100,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.51% Airbnb Rental Income: $null Traditional Rental Income: $722 Airbnb ROI: N/A Traditional ROI: 4.51%
394 Violet Ln Doniphan, MO Welcome to your FULLY FURNISHED, private riverfront paradise on the beautiful Current Rive...	4 beds \| 4 baths \| 3,599 sq.ft.	$1,399,900	Airbnb cash on cash: -0.2% Traditional cash on cash: 1.72% Airbnb Rental Income: $1965 Traditional Rental Income: $3943 Airbnb ROI: -0.2% Traditional ROI: 1.72%
2977 Ripley Route A Doniphan, MO Very attractive 1,800 sq. ft. modular home, with metal roof, built in 2006. This 3 bedroom...	3 beds \| 2 baths \| 1,800 sq.ft.	$224,000	Airbnb cash on cash: -0.67% Traditional cash on cash: 7.75% Airbnb Rental Income: $477 Traditional Rental Income: $1992 Airbnb ROI: -0.67% Traditional ROI: 7.75%
1004 Barton Rd Doniphan, MO Check out this really nice affordable home just outside the city limits of Doniphan! This ...	3 beds \| 2 baths \| 2,016 sq.ft.	$189,500	Airbnb cash on cash: -0.77% Traditional cash on cash: 9.56% Airbnb Rental Income: $477 Traditional Rental Income: $2068 Airbnb ROI: -0.77% Traditional ROI: 9.56%
15 Icehouse Ln Doniphan, MO	N/A beds \| N/A baths \| N/A	$125,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.97% Airbnb Rental Income: $null Traditional Rental Income: $806 Airbnb ROI: N/A Traditional ROI: 3.97%
38 Ripley E #U4-B Doniphan, MO 38 Ripley E #U4-B, Doniphan, MO 63935 \| Single Family Residential	3 beds \| 2 baths \| 1,456 sq.ft.	$409,000	Airbnb cash on cash: -1.66% Traditional cash on cash: 1.56% Airbnb Rental Income: $477 Traditional Rental Income: $1444 Airbnb ROI: -1.66% Traditional ROI: 1.56%
207 Jackson St Doniphan, MO Quaint two-bedroom, one-bath home located just minutes from Current River and in city limi...	2 beds \| 1 baths \| 928 sq.ft.	$125,000	Airbnb cash on cash: -1.91% Traditional cash on cash: 7.49% Airbnb Rental Income: $241 Traditional Rental Income: $1144 Airbnb ROI: -1.91% Traditional ROI: 7.49%
201 Ripley E-4 Doniphan, MO This home has been completely renovated from top to bottom-giving you the charm of a river...	3 beds \| 2 baths \| 1,900 sq.ft.	$219,000	Airbnb cash on cash: -0.9% Traditional cash on cash: 8.28% Airbnb Rental Income: $477 Traditional Rental Income: $2113 Airbnb ROI: -0.9% Traditional ROI: 8.28%
220 Ripley 160e-8 Doniphan, MO Welcome home to this charming 3-bedroom, 2.5-bath gem featuring a super cute open floor pl...	3 beds \| 2 baths \| 2,000 sq.ft.	$225,000	Airbnb cash on cash: -0.75% Traditional cash on cash: 8.09% Airbnb Rental Income: $477 Traditional Rental Income: $2092 Airbnb ROI: -0.75% Traditional ROI: 8.09%
3 Oxen Pasture Rd Doniphan, MO 3 Oxen Pasture Rd, Doniphan, MO 63935 \| Other	N/A beds \| N/A baths \| N/A	$70,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.71% Airbnb Rental Income: $null Traditional Rental Income: $834 Airbnb ROI: N/A Traditional ROI: 8.71%

Real Estate investment in Doniphan, MO

There are 63 properties for sale in the city of Doniphan . The median list price in Doniphan is $235,000 and the average price per square foot is $116. In May 2026, the average monthly cash on cash return in Doniphan is 7.00%. The average monthly rental income in Doniphan is $1,802.

Doniphan, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 63 investment properties available for sale in Doniphan.

In 2026, the best neighborhood to buy investment property is Doniphan.

The ROI for Long-Term is higher than the Short-Term in Doniphan with average rental income of $1,802.

Your search for investment property begins and ends here

Investment Property for Sale in Doniphan, MO

4396 State Highway 21

Doniphan, MO

3 beds | 2 baths | 2,064 sq.ft.

$269,900

Airbnb cash on cash: -0.74%

Traditional cash on cash: 6.63%

Airbnb Rental Income: $477

Traditional Rental Income: $2084

Airbnb ROI: -0.74%

Traditional ROI: 6.63%

4795 Ripley K-1

Doniphan, MO

4 beds | 2 baths | 1,800 sq.ft.

$274,999

Airbnb cash on cash: 3.83%

Traditional cash on cash: 5.87%

Airbnb Rental Income: $1965

Traditional Rental Income: $1978

Airbnb ROI: 3.83%

Traditional ROI: 5.87%

1901 River Valley Road

Doniphan, MO

3 beds | 3 baths | 1,834 sq.ft.

$674,900

Airbnb cash on cash: -1.11%

Traditional cash on cash: 2.6%

Airbnb Rental Income: $477

Traditional Rental Income: $2540

Airbnb ROI: -1.11%

Traditional ROI: 2.6%

81 Southern Comfort

Doniphan, MO

3 beds | 2 baths | 1,440 sq.ft.

$595,000

Airbnb cash on cash: -0.97%

Traditional cash on cash: 1.81%

Airbnb Rental Income: $477

Traditional Rental Income: $1750

Airbnb ROI: -0.97%

Traditional ROI: 1.81%

249 Trails End Way

Doniphan, MO

3 beds | 1 baths | 1,388 sq.ft.

$219,000

Airbnb cash on cash: -0.81%

Traditional cash on cash: 7.03%

Airbnb Rental Income: $477

Traditional Rental Income: $1835

Airbnb ROI: -0.81%

Traditional ROI: 7.03%

6029 Ripley Rt V

Doniphan, MO

3 beds | 3 baths | 3,067 sq.ft.

$399,000

Airbnb cash on cash: -1.02%

Traditional cash on cash: 5.42%

Airbnb Rental Income: $477

Traditional Rental Income: $2619

Airbnb ROI: -1.02%

Traditional ROI: 5.42%

64 Trails End Ln

Doniphan, MO

3 beds | 3 baths | 2,801 sq.ft.

$425,000

Airbnb cash on cash: -0.95%

Traditional cash on cash: 6.9%

Airbnb Rental Income: $477

Traditional Rental Income: $3331

Airbnb ROI: -0.95%

Traditional ROI: 6.9%

936 Crawdad Lane

Doniphan, MO

4 beds | 2 baths | 2,997 sq.ft.

$749,900

Airbnb cash on cash: 0.75%

Traditional cash on cash: 2.51%

Airbnb Rental Income: $1965

Traditional Rental Income: $2677

Airbnb ROI: 0.75%