Real Estate Investment Properties for Sale in East Prairie, MO

Looking for investment property in East Prairie, MO with high ROI ?

Explore a variety of short-term homes & houses in East Prairie, MO. Invest wisely with VRBO & East Prairie, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in East Prairie, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
412 Williams Street East Prairie, MO Fall in love with this charming 3 bed 2 bath ranch offers comfortable living on a quiet st...	3 beds \| 2 baths \| 1,852 sq.ft.	$199,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.51% Airbnb Rental Income: $null Traditional Rental Income: $2459 Airbnb ROI: N/A Traditional ROI: 11.51%
702 S 525th Rd East Prairie, MO New Price Reduction Look no further, if you are in the market for 4 bed 3.5 bath home, t...	4 beds \| 3 baths \| 2,108 sq.ft.	$360,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.05% Airbnb Rental Income: $null Traditional Rental Income: $2988 Airbnb ROI: N/A Traditional ROI: 7.05%
52 Michael Lane East Prairie, MO Location! Take a look at this Move in Ready Home. Sitting on 1.1 acres just outside city l...	3 beds \| 2 baths \| 1,776 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.81% Airbnb Rental Income: $null Traditional Rental Income: $1847 Airbnb ROI: N/A Traditional ROI: 4.81%
226 Sandy Ln East Prairie, MO 226 Sandy Ln, East Prairie, MO 63845 \| Single Family Residential	5 beds \| 3 baths \| 2,610 sq.ft.	$268,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.4% Airbnb Rental Income: $null Traditional Rental Income: $2712 Airbnb ROI: N/A Traditional ROI: 8.4%
49 Betty Sue Drive East Prairie, MO Great location for this 3 bedroom and 2.5 bath home. With just over 2 acres and plenty of...	3 beds \| 3 baths \| 2,192 sq.ft.	$264,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.43% Airbnb Rental Income: $null Traditional Rental Income: $2431 Airbnb ROI: N/A Traditional ROI: 7.43%
445 Margaret Dr East Prairie, MO 445 Margaret Dr, East Prairie, MO 63845 \| Single Family Residential	4 beds \| 2 baths \| 2,566 sq.ft.	$235,000	Airbnb cash on cash: N/A Traditional cash on cash: 8% Airbnb Rental Income: $null Traditional Rental Income: $2306 Airbnb ROI: N/A Traditional ROI: 8%
200 Margaret Dr East Prairie, MO 200 Margaret Dr, East Prairie, MO 63845 \| Single Family Residential	2 beds \| 2 baths \| 1,888 sq.ft.	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.54% Airbnb Rental Income: $null Traditional Rental Income: $948 Airbnb ROI: N/A Traditional ROI: 2.54%
20 & 30 Artic Ln East Prairie, MO 20 & 30 Artic Ln, East Prairie, MO 63845 \| Single Family Residential	3 beds \| 1 baths \| 1,158 sq.ft.	$175,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.89% Airbnb Rental Income: $null Traditional Rental Income: $1567 Airbnb ROI: N/A Traditional ROI: 6.89%
Hwy FF Hwy East Prairie, MO Hwy FF Hwy, East Prairie, MO 64628 \| Other	N/A beds \| N/A baths \| N/A	$696,800	Airbnb cash on cash: N/A Traditional cash on cash: -0.74% Airbnb Rental Income: $null Traditional Rental Income: $885 Airbnb ROI: N/A Traditional ROI: -0.74%
511W Main East Prairie, MO This beautiful ranch style home has been completely remodeled. Offering you a move in read...	4 beds \| 2 baths \| 1,740 sq.ft.	$185,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.88% Airbnb Rental Income: $null Traditional Rental Income: $2353 Airbnb ROI: N/A Traditional ROI: 10.88%
209 Williams East Prairie, MO Charm and character just begin to describe this 3 bedroom and 1 3/4 bath home. Custom kit...	3 beds \| 2 baths \| 1,704 sq.ft.	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.85% Airbnb Rental Income: $null Traditional Rental Income: $2334 Airbnb ROI: N/A Traditional ROI: 9.85%
305 Bill Pope Road East Prairie, MO !!New Price !! Welcome to this inviting 1056 sq ft 2 bedroom 2 full bath home tucked away ...	2 beds \| 2 baths \| 1,056 sq.ft.	$165,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.2% Airbnb Rental Income: $null Traditional Rental Income: $1691 Airbnb ROI: N/A Traditional ROI: 8.2%
310 Defield East Prairie, MO Beautifully completely Remodeled home situated on 2.31 acres. Tucked back from street and ...	3 beds \| 3 baths \| 2,035 sq.ft.	$385,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.09% Airbnb Rental Income: $null Traditional Rental Income: $2772 Airbnb ROI: N/A Traditional ROI: 6.09%
26 Betty Sue Drive East Prairie, MO Beautiful and well maintained home! Outdoor at it's finest from wraparound porch, bri...	4 beds \| 3 baths \| 2,062 sq.ft.	$295,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.93% Airbnb Rental Income: $null Traditional Rental Income: $2448 Airbnb ROI: N/A Traditional ROI: 6.93%
313 W Pine St East Prairie, MO 313 W Pine St, East Prairie, MO 63845 \| Single Family Residential	3 beds \| 2 baths \| 1,327 sq.ft.	$149,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.01% Airbnb Rental Income: $null Traditional Rental Income: $1799 Airbnb ROI: N/A Traditional ROI: 10.01%
209 E Pine St East Prairie, MO 209 E Pine St, East Prairie, MO 63845 \| Single Family Residential	3 beds \| 2 baths \| 1,608 sq.ft.	$180,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.91% Airbnb Rental Income: $null Traditional Rental Income: $2127 Airbnb ROI: N/A Traditional ROI: 9.91%

Real Estate investment in East-prairie, MO

There are 16 properties for sale in the city of East Prairie . The median list price in East Prairie is $180,000 and the average price per square foot is $107. In May 2026, the average monthly cash on cash return in East Prairie is 10.00%. The average monthly rental income in East Prairie is $1,799.

East-prairie, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 16 investment properties available for sale in East-prairie.

The ROI for Short-Term is higher than the Long-Term in East-prairie with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in East Prairie, MO

412 Williams Street

East Prairie, MO

3 beds | 2 baths | 1,852 sq.ft.

$199,000

Airbnb cash on cash: N/A

Traditional cash on cash: 11.51%

Airbnb Rental Income: $null

Traditional Rental Income: $2459

Airbnb ROI: N/A

Traditional ROI: 11.51%

702 S 525th Rd

East Prairie, MO

4 beds | 3 baths | 2,108 sq.ft.

$360,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.05%

Airbnb Rental Income: $null

Traditional Rental Income: $2988

Airbnb ROI: N/A

Traditional ROI: 7.05%

52 Michael Lane

East Prairie, MO

3 beds | 2 baths | 1,776 sq.ft.

$275,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.81%

Airbnb Rental Income: $null

Traditional Rental Income: $1847

Airbnb ROI: N/A

Traditional ROI: 4.81%

226 Sandy Ln

East Prairie, MO

5 beds | 3 baths | 2,610 sq.ft.

$268,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.4%

Airbnb Rental Income: $null

Traditional Rental Income: $2712

Airbnb ROI: N/A

Traditional ROI: 8.4%

49 Betty Sue Drive

East Prairie, MO

3 beds | 3 baths | 2,192 sq.ft.

$264,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.43%

Airbnb Rental Income: $null

Traditional Rental Income: $2431

Airbnb ROI: N/A

Traditional ROI: 7.43%

445 Margaret Dr

East Prairie, MO

4 beds | 2 baths | 2,566 sq.ft.

$235,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8%

Airbnb Rental Income: $null

Traditional Rental Income: $2306

Airbnb ROI: N/A

Traditional ROI: 8%

200 Margaret Dr

East Prairie, MO

2 beds | 2 baths | 1,888 sq.ft.

$199,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.54%

Airbnb Rental Income: $null

Traditional Rental Income: $948

Airbnb ROI: N/A

Traditional ROI: 2.54%

20 & 30 Artic Ln

East Prairie, MO

3 beds | 1 baths | 1,158 sq.ft.

$175,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.89%

Airbnb Rental Income: $null

Traditional Rental Income: $1567

Airbnb ROI: N/A