Real Estate Investment Properties for Sale in Fredericktown, MO

Looking for investment property in Fredericktown, MO with high ROI ?

Explore a variety of short-term homes & houses in Fredericktown, MO. Invest wisely with VRBO & Fredericktown, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Fredericktown, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1108 Madison 209 Fredericktown, MO Charming Home, County Living at its Finest. This home is a quiet, peaceful, tucked away ge...	4 beds \| 1 baths \| 1,260 sq.ft.	$194,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.86% Airbnb Rental Income: $null Traditional Rental Income: $1449 Airbnb ROI: N/A Traditional ROI: 5.86%
2424 MADISON 504 Fredericktown, MO Invest with success and buy through Auction.com. This bank-owned investment property is a ...	3 beds \| 2 baths \| 1,960 sq.ft.	$262,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.69% Airbnb Rental Income: $null Traditional Rental Income: $2065 Airbnb ROI: N/A Traditional ROI: 6.69%
1507 Highway OO Fredericktown, MO Located at 1507 Highway OO, Fredericktown, MO, this single-family residence presents a won...	5 beds \| 2 baths \| 2,825 sq.ft.	$375,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.97% Airbnb Rental Income: $null Traditional Rental Income: $3041 Airbnb ROI: N/A Traditional ROI: 6.97%
1470 Madison 208 Fredericktown, MO Add this one to your list. Sitting on 1.45 acre lot is where you will find this 3 bed/2 ba...	3 beds \| 2 baths \| 1,440 sq.ft.	$270,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.57% Airbnb Rental Income: $null Traditional Rental Income: $1866 Airbnb ROI: N/A Traditional ROI: 5.57%
311 Albert St Fredericktown, MO Great family home with 4 bedrooms, 2 baths, office space, kitchen, living room, dining roo...	4 beds \| 2 baths \| 1,431 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.06% Airbnb Rental Income: $null Traditional Rental Income: $1605 Airbnb ROI: N/A Traditional ROI: 7.06%
1121 Madison 92103 Fredericktown, MO This stunning and private 1.5 story house with 2874 sqft (3558 sqft total living space inc...	4 beds \| 3 baths \| 3,558 sq.ft.	$539,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.3% Airbnb Rental Income: $null Traditional Rental Income: $3449 Airbnb ROI: N/A Traditional ROI: 5.3%
1555 Madison 530 Fredericktown, MO Step back in time while enjoying modern-day luxury with this stunning 160-year-old log hom...	2 beds \| 3 baths \| 2,697 sq.ft.	$479,900	Airbnb cash on cash: 0.08% Traditional cash on cash: 4.06% Airbnb Rental Income: $986 Traditional Rental Income: $2422 Airbnb ROI: 0.08% Traditional ROI: 4.06%
100 Cool Breeze Ln Fredericktown, MO Live off the grid on this 20 acres of flat to rolling hills just a short gravel drive from...	1 beds \| 1 baths \| 240 sq.ft.	$385,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.92% Airbnb Rental Income: $null Traditional Rental Income: $1193 Airbnb ROI: N/A Traditional ROI: 1.92%
1433 Madison 9558 Fredericktown, MO Charming Riverfront Cabin on the St. Francois River. Beautifully furnished 2-bedroom, 1-ba...	2 beds \| 1 baths \| 903 sq.ft.	$219,900	Airbnb cash on cash: 1.31% Traditional cash on cash: 3.96% Airbnb Rental Income: $986 Traditional Rental Income: $1184 Airbnb ROI: 1.31% Traditional ROI: 3.96%
0 S Mine La Motte Ave Fredericktown, MO 0 S Mine La Motte Ave, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$900,000	Airbnb cash on cash: -2.05% Traditional cash on cash: -1.2% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.05% Traditional ROI: -1.2%
505 Villar St Fredericktown, MO 505 Villar St, Fredericktown, MO 63645 \| Single Family Residential	3 beds \| 2 baths \| 1,050 sq.ft.	$162,500	Airbnb cash on cash: N/A Traditional cash on cash: 5.74% Airbnb Rental Income: $null Traditional Rental Income: $1286 Airbnb ROI: N/A Traditional ROI: 5.74%
209 W College Fredericktown, MO 209 W College, Fredericktown, MO 63645 \| Single Family Residential	2 beds \| 2 baths \| 1,355 sq.ft.	$169,500	Airbnb cash on cash: 1.38% Traditional cash on cash: 3.14% Airbnb Rental Income: $986 Traditional Rental Income: $917 Airbnb ROI: 1.38% Traditional ROI: 3.14%
1126 South Deer Trl Fredericktown, MO 1126 South Deer Trl, Fredericktown, MO 63645 \| Single Family Residential	4 beds \| 2 baths \| 1,568 sq.ft.	$269,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.4% Airbnb Rental Income: $null Traditional Rental Income: $1533 Airbnb ROI: N/A Traditional ROI: 3.4%
129 Madison CR 410 Fredericktown, MO 129 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$49,900	Airbnb cash on cash: -3.4% Traditional cash on cash: 10.65% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.4% Traditional ROI: 10.65%
184 Madison CR 410 Fredericktown, MO 184 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$72,995	Airbnb cash on cash: -2.98% Traditional cash on cash: 6.91% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.98% Traditional ROI: 6.91%
183 Madison CR 410 Fredericktown, MO 183 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$78,995	Airbnb cash on cash: -2.91% Traditional cash on cash: 6.27% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.91% Traditional ROI: 6.27%
11834 Highway 67 Fredericktown, MO 11834 Highway 67, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$149,999	Airbnb cash on cash: -2.47% Traditional cash on cash: 2.5% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.47% Traditional ROI: 2.5%
182 Madison CR 410 Fredericktown, MO 182 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$68,195	Airbnb cash on cash: -3.05% Traditional cash on cash: 7.58% Airbnb Rental Income: $249 Traditional Rental Income: $739 Airbnb ROI: -3.05% Traditional ROI: 7.58%
302 Madison CR 410 Fredericktown, MO 302 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$74,000	Airbnb cash on cash: -2.97% Traditional cash on cash: 6.79% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.97% Traditional ROI: 6.79%
181 Madison CR 410 Fredericktown, MO 181 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$71,695	Airbnb cash on cash: -3% Traditional cash on cash: 7.06% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3% Traditional ROI: 7.06%
10535 Hwy 67 Fredericktown, MO 10535 Hwy 67, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$239,999	Airbnb cash on cash: -2.29% Traditional cash on cash: 0.86% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.29% Traditional ROI: 0.86%
176 Madison CR 410 Fredericktown, MO 176 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$46,495	Airbnb cash on cash: -3.51% Traditional cash on cash: 11.47% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.51% Traditional ROI: 11.47%
172 Madison CR 410 Fredericktown, MO 172 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$61,995	Airbnb cash on cash: -3.15% Traditional cash on cash: 8.37% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.15% Traditional ROI: 8.37%
173 Madison CR 410 Fredericktown, MO 173 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$61,995	Airbnb cash on cash: -3.15% Traditional cash on cash: 8.37% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.15% Traditional ROI: 8.37%
6 Mo-72 Fredericktown, MO 6 Mo-72, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| 756 sq.ft.	$71,500	Airbnb cash on cash: -3% Traditional cash on cash: 7.08% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3% Traditional ROI: 7.08%
2 Mo-72 Fredericktown, MO 2 Mo-72, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$49,900	Airbnb cash on cash: -3.4% Traditional cash on cash: 10.65% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.4% Traditional ROI: 10.65%
1261 W Main St Fredericktown, MO 1261 W Main St, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$100,000	Airbnb cash on cash: -2.72% Traditional cash on cash: 4.63% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.72% Traditional ROI: 4.63%
2 Cr 528 Fredericktown, MO 2 Cr 528, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$49,900	Airbnb cash on cash: -3.4% Traditional cash on cash: 10.65% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.4% Traditional ROI: 10.65%
5 Cr 528 Fredericktown, MO 5 Cr 528, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$50,000	Airbnb cash on cash: -3.4% Traditional cash on cash: 10.63% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.4% Traditional ROI: 10.63%
7 CR 528 Fredericktown, MO 7 CR 528, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$60,000	Airbnb cash on cash: -3.19% Traditional cash on cash: 8.68% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.19% Traditional ROI: 8.68%
5 Mo-72 Fredericktown, MO 5 Mo-72, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$78,500	Airbnb cash on cash: -2.91% Traditional cash on cash: 6.33% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.91% Traditional ROI: 6.33%
1 Mo-72 Fredericktown, MO 1 Mo-72, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$64,900	Airbnb cash on cash: -3.09% Traditional cash on cash: 8.97% Airbnb Rental Income: $249 Traditional Rental Income: $799 Airbnb ROI: -3.09% Traditional ROI: 8.97%
175 Madison CR 410 Fredericktown, MO 175 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$67,595	Airbnb cash on cash: -3.06% Traditional cash on cash: 7.56% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.06% Traditional ROI: 7.56%
6 Cr 528 Fredericktown, MO 6 Cr 528, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$50,000	Airbnb cash on cash: -3.4% Traditional cash on cash: 10.63% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -3.4% Traditional ROI: 10.63%
304 Madison CR 410 Fredericktown, MO 304 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$74,000	Airbnb cash on cash: -2.97% Traditional cash on cash: 6.79% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.97% Traditional ROI: 6.79%
185 Madison CR 410 Fredericktown, MO 185 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$82,995	Airbnb cash on cash: -2.86% Traditional cash on cash: 5.9% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.86% Traditional ROI: 5.9%
186 Madison CR 410 Fredericktown, MO 186 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$72,995	Airbnb cash on cash: -2.98% Traditional cash on cash: 6.91% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.98% Traditional ROI: 6.91%
189 Madison CR 410 Fredericktown, MO 189 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$84,995	Airbnb cash on cash: -2.85% Traditional cash on cash: 5.72% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.85% Traditional ROI: 5.72%
188 Madison CR 410 Fredericktown, MO 188 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$80,995	Airbnb cash on cash: -2.88% Traditional cash on cash: 6.09% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.88% Traditional ROI: 6.09%
303 Madison CR 410 Fredericktown, MO 303 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$97,995	Airbnb cash on cash: -2.73% Traditional cash on cash: 4.76% Airbnb Rental Income: $249 Traditional Rental Income: $733 Airbnb ROI: -2.73% Traditional ROI: 4.76%

Real Estate investment in Fredericktown, MO

There are 79 properties for sale in the city of Fredericktown . The median list price in Fredericktown is $76,700 and the average price per square foot is $40. In May 2026, the average monthly cash on cash return in Fredericktown is 7.00%. The average monthly rental income in Fredericktown is $756.

Fredericktown, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 79 investment properties available for sale in Fredericktown.

In 2026, the best neighborhood to buy investment property is Fredericktown.

The ROI for Long-Term is higher than the Short-Term in Fredericktown with average rental income of $756.

Your search for investment property begins and ends here

Investment Property for Sale in Fredericktown, MO

1108 Madison 209

Fredericktown, MO

4 beds | 1 baths | 1,260 sq.ft.

$194,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.86%

Airbnb Rental Income: $null

Traditional Rental Income: $1449

Airbnb ROI: N/A

Traditional ROI: 5.86%

2424 MADISON 504

Fredericktown, MO

3 beds | 2 baths | 1,960 sq.ft.

$262,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.69%

Airbnb Rental Income: $null

Traditional Rental Income: $2065

Airbnb ROI: N/A

Traditional ROI: 6.69%

1507 Highway OO

Fredericktown, MO

5 beds | 2 baths | 2,825 sq.ft.

$375,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.97%

Airbnb Rental Income: $null

Traditional Rental Income: $3041

Airbnb ROI: N/A

Traditional ROI: 6.97%

1470 Madison 208

Fredericktown, MO

3 beds | 2 baths | 1,440 sq.ft.

$270,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.57%

Airbnb Rental Income: $null

Traditional Rental Income: $1866

Airbnb ROI: N/A

Traditional ROI: 5.57%

311 Albert St

Fredericktown, MO

4 beds | 2 baths | 1,431 sq.ft.

$189,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.06%

Airbnb Rental Income: $null

Traditional Rental Income: $1605

Airbnb ROI: N/A

Traditional ROI: 7.06%

1121 Madison 92103

Fredericktown, MO

4 beds | 3 baths | 3,558 sq.ft.

$539,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.3%

Airbnb Rental Income: $null

Traditional Rental Income: $3449

Airbnb ROI: N/A

Traditional ROI: 5.3%

1555 Madison 530

Fredericktown, MO

2 beds | 3 baths | 2,697 sq.ft.

$479,900

Airbnb cash on cash: 0.08%

Traditional cash on cash: 4.06%

Airbnb Rental Income: $986

Traditional Rental Income: $2422

Airbnb ROI: 0.08%

Traditional ROI: 4.06%

100 Cool Breeze Ln

Fredericktown, MO

1 beds | 1 baths | 240 sq.ft.

$385,000

Airbnb cash on cash: N/A

Traditional cash on cash: 1.92%

Airbnb Rental Income: $null

Traditional Rental Income: $1193

Airbnb ROI: N/A