Real Estate Investment Properties for Sale in Fredericktown, MO

Looking for investment property in Fredericktown, MO with high ROI ?

Explore a variety of short-term homes & houses in Fredericktown, MO. Invest wisely with VRBO & Fredericktown, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Fredericktown, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1507 Highway OO Fredericktown, MO Located at 1507 Highway OO, Fredericktown, MO, this single-family residence presents a won...	5 beds \| 3 baths \| 2,825 sq.ft.	$339,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.81% Airbnb Rental Income: $null Traditional Rental Income: $3041 Airbnb ROI: N/A Traditional ROI: 7.81%
1226 S Deer Trl Fredericktown, MO This spacious home is beautifully maintained, features a brand new roof and located right...	4 beds \| 3 baths \| 3,480 sq.ft.	$485,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.92% Airbnb Rental Income: $null Traditional Rental Income: $2058 Airbnb ROI: N/A Traditional ROI: 2.92%
1515 Madison 404 Fredericktown, MO Welcome to your dream home, remodeled in 2018 with new flooring added in 2024. This 3-bed,...	3 beds \| 3 baths \| 2,442 sq.ft.	$352,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.93% Airbnb Rental Income: $null Traditional Rental Income: $2544 Airbnb ROI: N/A Traditional ROI: 5.93%
8076 T Hwy Fredericktown, MO Discover the perfect blend of comfort and nature in this inviting 3-bedroom home set on a ...	3 beds \| 2 baths \| 1,288 sq.ft.	$375,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.59% Airbnb Rental Income: $null Traditional Rental Income: $1827 Airbnb ROI: N/A Traditional ROI: 3.59%
10 Lisa Drive Fredericktown, MO Move-in ready and tucked away on a dead-end street in the city limits of Fredericktown! Th...	3 beds \| 1 baths \| 1,008 sq.ft.	$164,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.86% Airbnb Rental Income: $null Traditional Rental Income: $1374 Airbnb ROI: N/A Traditional ROI: 6.86%
1433 Madison 9558 Fredericktown, MO Charming Riverfront Cabin on the St. Francois River. Beautifully furnished 2-bedroom, 1-ba...	2 beds \| 1 baths \| 903 sq.ft.	$219,900	Airbnb cash on cash: 6.21% Traditional cash on cash: 3.96% Airbnb Rental Income: $2210 Traditional Rental Income: $1184 Airbnb ROI: 6.21% Traditional ROI: 3.96%
7 Ivy Ln Fredericktown, MO 7 Ivy Ln, Fredericktown, MO 63645 \| Condo/Coop	N/A beds \| N/A baths \| 1,478 sq.ft.	$229,999	Airbnb cash on cash: -0.61% Traditional cash on cash: 4.86% Airbnb Rental Income: $850 Traditional Rental Income: $1710 Airbnb ROI: -0.61% Traditional ROI: 4.86%
1126 S Deer Trl Fredericktown, MO 1126 South Deer Trl, Fredericktown, MO 63645 \| Single Family Residential	4 beds \| 2 baths \| 1,068 sq.ft.	$254,888	Airbnb cash on cash: N/A Traditional cash on cash: 3.87% Airbnb Rental Income: $null Traditional Rental Income: $1533 Airbnb ROI: N/A Traditional ROI: 3.87%
129 Madison CR 410 Fredericktown, MO 129 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$44,995	Airbnb cash on cash: 7.28% Traditional cash on cash: 11.89% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 7.28% Traditional ROI: 11.89%
184 Madison CR 410 Fredericktown, MO 184 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$72,995	Airbnb cash on cash: 3.95% Traditional cash on cash: 6.91% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.95% Traditional ROI: 6.91%
183 Madison CR 410 Fredericktown, MO 183 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$78,995	Airbnb cash on cash: 3.53% Traditional cash on cash: 6.27% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.53% Traditional ROI: 6.27%
182 Madison CR 410 Fredericktown, MO 182 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$68,195	Airbnb cash on cash: 4.34% Traditional cash on cash: 7.58% Airbnb Rental Income: $850 Traditional Rental Income: $739 Airbnb ROI: 4.34% Traditional ROI: 7.58%
302 Madison CR 410 Fredericktown, MO 302 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$74,000	Airbnb cash on cash: 3.88% Traditional cash on cash: 6.79% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.88% Traditional ROI: 6.79%
181 Madison CR 410 Fredericktown, MO 181 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$71,695	Airbnb cash on cash: 4.05% Traditional cash on cash: 7.06% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 4.05% Traditional ROI: 7.06%
10535 Hwy 67 Fredericktown, MO 10535 Hwy 67, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$217,000	Airbnb cash on cash: 0.12% Traditional cash on cash: 1.16% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 0.12% Traditional ROI: 1.16%
176 Madison CR 410 Fredericktown, MO 176 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$46,495	Airbnb cash on cash: 6.99% Traditional cash on cash: 11.47% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 6.99% Traditional ROI: 11.47%
172 Madison CR 410 Fredericktown, MO 172 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$58,995	Airbnb cash on cash: 5.24% Traditional cash on cash: 8.85% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 5.24% Traditional ROI: 8.85%
173 Madison CR 410 Fredericktown, MO 173 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$58,995	Airbnb cash on cash: 5.24% Traditional cash on cash: 8.85% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 5.24% Traditional ROI: 8.85%
1261 W Main St Fredericktown, MO 1261 W Main St, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$100,000	Airbnb cash on cash: 2.43% Traditional cash on cash: 4.63% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 2.43% Traditional ROI: 4.63%
0 10.189 Acres Off Madison 534 Fredericktown, MO 0 10.189 Acres Off Madison 534, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$84,900	Airbnb cash on cash: 3.17% Traditional cash on cash: 5.73% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.17% Traditional ROI: 5.73%
5 Cr 528 Fredericktown, MO 5 Cr 528, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$50,000	Airbnb cash on cash: 6.44% Traditional cash on cash: 10.63% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 6.44% Traditional ROI: 10.63%
7 CR 528 Fredericktown, MO 7 CR 528, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$60,000	Airbnb cash on cash: 5.13% Traditional cash on cash: 8.68% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 5.13% Traditional ROI: 8.68%
175 Madison CR 410 Fredericktown, MO 175 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$67,595	Airbnb cash on cash: 4.39% Traditional cash on cash: 7.56% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 4.39% Traditional ROI: 7.56%
185 Madison CR 410 Fredericktown, MO 185 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$82,995	Airbnb cash on cash: 3.28% Traditional cash on cash: 5.9% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.28% Traditional ROI: 5.9%
186 Madison CR 410 Fredericktown, MO 186 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$72,995	Airbnb cash on cash: 3.95% Traditional cash on cash: 6.91% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.95% Traditional ROI: 6.91%
189 Madison CR 410 Fredericktown, MO 189 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$84,995	Airbnb cash on cash: 3.16% Traditional cash on cash: 5.72% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.16% Traditional ROI: 5.72%
188 Madison CR 410 Fredericktown, MO 188 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$80,995	Airbnb cash on cash: 3.41% Traditional cash on cash: 6.09% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.41% Traditional ROI: 6.09%
303 Madison CR 410 Fredericktown, MO 303 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$97,995	Airbnb cash on cash: 2.52% Traditional cash on cash: 4.76% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 2.52% Traditional ROI: 4.76%
187 Madison CR 410 Fredericktown, MO 187 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$78,995	Airbnb cash on cash: 3.53% Traditional cash on cash: 6.27% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.53% Traditional ROI: 6.27%
13907 #2 Highway T Fredericktown, MO 13907 Highway T, Fredericktown, MO 63645 \| Single Family Residential	5 beds \| 4 baths \| 3,980 sq.ft.	$484,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.46% Airbnb Rental Income: $null Traditional Rental Income: $3007 Airbnb ROI: N/A Traditional ROI: 4.46%
197 Madison CR 410 Fredericktown, MO 197 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$75,000	Airbnb cash on cash: 3.8% Traditional cash on cash: 6.68% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.8% Traditional ROI: 6.68%
198 Madison CR 410 Fredericktown, MO 198 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$85,995	Airbnb cash on cash: 3.1% Traditional cash on cash: 5.64% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 3.1% Traditional ROI: 5.64%
0 Bidwell Creek Rd Fredericktown, MO 0 Bidwell Creek Rd, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$114,900	Airbnb cash on cash: 1.88% Traditional cash on cash: 3.81% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 1.88% Traditional ROI: 3.81%
199 Madison CR 410 Fredericktown, MO 199 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$46,995	Airbnb cash on cash: 6.91% Traditional cash on cash: 11.35% Airbnb Rental Income: $850 Traditional Rental Income: $733 Airbnb ROI: 6.91% Traditional ROI: 11.35%
200 Madison CR 410 Fredericktown, MO 200 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$74,395	Airbnb cash on cash: 3.85% Traditional cash on cash: 6.84% Airbnb Rental Income: $850 Traditional Rental Income: $739 Airbnb ROI: 3.85% Traditional ROI: 6.84%
204 Madison CR 410 Fredericktown, MO 204 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$67,500	Airbnb cash on cash: 4.4% Traditional cash on cash: 7.67% Airbnb Rental Income: $850 Traditional Rental Income: $739 Airbnb ROI: 4.4% Traditional ROI: 7.67%
208 Madison CR 410 Fredericktown, MO 208 Madison CR 410, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$54,845	Airbnb cash on cash: 5.76% Traditional cash on cash: 9.72% Airbnb Rental Income: $850 Traditional Rental Income: $739 Airbnb ROI: 5.76% Traditional ROI: 9.72%
2049 Madison 208 Fredericktown, MO BRAND NEW ROOF (2026), NEW HVAC (2026), Welcome to your private slice of Missouri paradise...	3 beds \| 2 baths \| 2,518 sq.ft.	$415,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.71% Airbnb Rental Income: $null Traditional Rental Income: $2429 Airbnb ROI: N/A Traditional ROI: 4.71%
707 Buford Blvd Fredericktown, MO 707 Buford Blvd, Fredericktown, MO 63645 \| Single Family Residential	4 beds \| 1 baths \| 1,936 sq.ft.	$220,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.17% Airbnb Rental Income: $null Traditional Rental Income: $1162 Airbnb ROI: N/A Traditional ROI: 3.17%
0 County Rd 229 Fredericktown, MO 0 County Rd 229, Fredericktown, MO 63645 \| Other	N/A beds \| N/A baths \| N/A	$78,000	Airbnb cash on cash: 3.6% Traditional cash on cash: 7.29% Airbnb Rental Income: $850 Traditional Rental Income: $803 Airbnb ROI: 3.6% Traditional ROI: 7.29%

Real Estate investment in Fredericktown, MO

There are 101 properties for sale in the city of Fredericktown . The median list price in Fredericktown is $158,375 and the average price per square foot is $95. In November 2026, the average monthly cash on cash return in Fredericktown is 9.00%. The average monthly rental income in Fredericktown is $831.

Fredericktown, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 101 investment properties available for sale in Fredericktown.

In 2026, the best neighborhood to buy investment property is Fredericktown.

The ROI for Long-Term is higher than the Short-Term in Fredericktown with average rental income of $831.

Your search for investment property begins and ends here

Investment Property for Sale in Fredericktown, MO

1507 Highway OO

Fredericktown, MO

5 beds | 3 baths | 2,825 sq.ft.

$339,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.81%

Airbnb Rental Income: $null

Traditional Rental Income: $3041

Airbnb ROI: N/A

Traditional ROI: 7.81%

1226 S Deer Trl

Fredericktown, MO

4 beds | 3 baths | 3,480 sq.ft.

$485,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.92%

Airbnb Rental Income: $null

Traditional Rental Income: $2058

Airbnb ROI: N/A

Traditional ROI: 2.92%

1515 Madison 404

Fredericktown, MO

3 beds | 3 baths | 2,442 sq.ft.

$352,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.93%

Airbnb Rental Income: $null

Traditional Rental Income: $2544

Airbnb ROI: N/A

Traditional ROI: 5.93%

8076 T Hwy

Fredericktown, MO

3 beds | 2 baths | 1,288 sq.ft.

$375,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.59%

Airbnb Rental Income: $null

Traditional Rental Income: $1827

Airbnb ROI: N/A

Traditional ROI: 3.59%

10 Lisa Drive

Fredericktown, MO

3 beds | 1 baths | 1,008 sq.ft.

$164,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.86%

Airbnb Rental Income: $null

Traditional Rental Income: $1374

Airbnb ROI: N/A

Traditional ROI: 6.86%

1433 Madison 9558

Fredericktown, MO

2 beds | 1 baths | 903 sq.ft.

$219,900

Airbnb cash on cash: 6.21%

Traditional cash on cash: 3.96%

Airbnb Rental Income: $2210

Traditional Rental Income: $1184

Airbnb ROI: 6.21%

Traditional ROI: 3.96%

7 Ivy Ln

Fredericktown, MO

N/A beds | N/A baths | 1,478 sq.ft.

$229,999

Airbnb cash on cash: -0.61%

Traditional cash on cash: 4.86%

Airbnb Rental Income: $850

Traditional Rental Income: $1710

Airbnb ROI: -0.61%

Traditional ROI: 4.86%

1126 S Deer Trl

Fredericktown, MO

4 beds | 2 baths | 1,068 sq.ft.

$254,888

Airbnb cash on cash: N/A

Traditional cash on cash: 3.87%

Airbnb Rental Income: $null

Traditional Rental Income: $1533

Airbnb ROI: N/A