Real Estate Investment Properties for Sale in Galena, MO

Looking for investment property in Galena, MO with high ROI ?

Explore a variety of short-term homes & houses in Galena, MO. Invest wisely with VRBO & Galena, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Galena, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1506 Meadowview Road Galena, MO Hold on tight! You are about to be BLOWN AWAY! Here is an amazing Lake Ready Package! This...	5 beds \| 3 baths \| 3,290 sq.ft.	$899,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.49% Airbnb Rental Income: $null Traditional Rental Income: $3136 Airbnb ROI: N/A Traditional ROI: 2.49%
1845 Sycamore Ranch Road Galena, MO Where luxury meets wide-open freedom.This isn't just a house-it's your own slice of Missou...	4 beds \| 4 baths \| 2,546 sq.ft.	$699,500	Airbnb cash on cash: N/A Traditional cash on cash: 2.62% Airbnb Rental Income: $null Traditional Rental Income: $2979 Airbnb ROI: N/A Traditional ROI: 2.62%
24880 State Hwy 413 Galena, MO Nestled on two peaceful acres in the heart of the Ozarks, this charming single-level home ...	2 beds \| 2 baths \| 1,148 sq.ft.	$250,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.84% Airbnb Rental Income: $null Traditional Rental Income: $1497 Airbnb ROI: N/A Traditional ROI: 4.84%
242 Weeping Willow Lane Galena, MO Discover the perfect blend of comfort & space in this stunning 5-bedroom, 3.5-bath home! E...	5 beds \| 4 baths \| 3,984 sq.ft.	$609,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.88% Airbnb Rental Income: $null Traditional Rental Income: $3103 Airbnb ROI: N/A Traditional ROI: 3.88%
251 Holly Lane Galena, MO This property business license for APT is now licensed in Stone county! This Surveyed 69.8...	3 beds \| 2 baths \| 1,990 sq.ft.	$999,900	Airbnb cash on cash: N/A Traditional cash on cash: 0.96% Airbnb Rental Income: $null Traditional Rental Income: $2077 Airbnb ROI: N/A Traditional ROI: 0.96%
251-A Holly Lane Galena, MO This property now has a 2025 business license for APT !! The Surveyed 69.8 acre property h...	3 beds \| 2 baths \| 1,990 sq.ft.	$999,900	Airbnb cash on cash: N/A Traditional cash on cash: 1.01% Airbnb Rental Income: $null Traditional Rental Income: $2122 Airbnb ROI: N/A Traditional ROI: 1.01%
251-B Holly Lane Galena, MO The business license for APT is now registered with Stone County. This Surveyed 69.8 acre ...	3 beds \| 2 baths \| 1,990 sq.ft.	$999,900	Airbnb cash on cash: N/A Traditional cash on cash: 1.01% Airbnb Rental Income: $null Traditional Rental Income: $2122 Airbnb ROI: N/A Traditional ROI: 1.01%
3030 Horsecreek Road Galena, MO Tucked away in the serene beauty of the Ozark mountains, this charming 2,800 sq ft home of...	4 beds \| 3 baths \| 2,800 sq.ft.	$499,995	Airbnb cash on cash: N/A Traditional cash on cash: 4.45% Airbnb Rental Income: $null Traditional Rental Income: $2646 Airbnb ROI: N/A Traditional ROI: 4.45%
60 Belle Haven Galena, MO Are you looking for your lake-community home or getaway. This property has everything you ...	3 beds \| 2 baths \| 1,800 sq.ft.	$229,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.13% Airbnb Rental Income: $null Traditional Rental Income: $1889 Airbnb ROI: N/A Traditional ROI: 7.13%
20 Hardin Hills Drive Galena, MO A New Year. A New Season. A Fresh Start @ 20 Hardin Hills Dr.Perched high above the pristi...	3 beds \| 3 baths \| 2,726 sq.ft.	$635,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.73% Airbnb Rental Income: $null Traditional Rental Income: $2461 Airbnb ROI: N/A Traditional ROI: 2.73%
460 Jackson Hollow Road Galena, MO A New Year. A New View. A Fresh Chapter Begins @ 460 Jackson Hollow Rd.Ring in new beginni...	5 beds \| 3 baths \| 3,005 sq.ft.	$535,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $2654 Airbnb ROI: N/A Traditional ROI: 3.86%
44 Centinnial Lane Galena, MO Are you looking for the perfect log-home? From the moment you drive up notice the welcomin...	3 beds \| 3 baths \| 3,538 sq.ft.	$549,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.51% Airbnb Rental Income: $null Traditional Rental Income: $2090 Airbnb ROI: N/A Traditional ROI: 2.51%
1035 State Highway Kk Galena, MO Welcome to your peaceful retreat nestled on 2.08 wooded acres in the Galena school distric...	3 beds \| 2 baths \| 1,372 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.29% Airbnb Rental Income: $null Traditional Rental Income: $1695 Airbnb ROI: N/A Traditional ROI: 6.29%
186 Carico Road Galena, MO * Price Improvement * Enjoy peaceful country living on 3.5 acres with this charming 3-...	3 beds \| 2 baths \| 1,064 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.56% Airbnb Rental Income: $null Traditional Rental Income: $1799 Airbnb ROI: N/A Traditional ROI: 5.56%
211 W 4th Street Galena, MO Welcome to 211 W 4th Street, a beautifully updated 4-bedroom, 2-bath home located just one...	4 beds \| 3 baths \| 1,559 sq.ft.	$170,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.75% Airbnb Rental Income: $null Traditional Rental Income: $2190 Airbnb ROI: N/A Traditional ROI: 11.75%
292 Golfers Lane Galena, MO Lake...Everyday at 292 Golfers Lane, Galena, MO, where every day begins and ends with the ...	3 beds \| 3 baths \| 1,904 sq.ft.	$349,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.82% Airbnb Rental Income: $null Traditional Rental Income: $2095 Airbnb ROI: N/A Traditional ROI: 4.82%
140 Libby Lane Galena, MO Put this on your ''Most Wanted'' List! Incredible lake front - lake view home in a very de...	4 beds \| 4 baths \| 3,752 sq.ft.	$750,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.31% Airbnb Rental Income: $null Traditional Rental Income: $4083 Airbnb ROI: N/A Traditional ROI: 4.31%
236 Riverside Drive Galena, MO Welcome to Riverside Retreat, a modern sanctuary tucked amid 17 acres of Ozarks tranquilit...	4 beds \| 4 baths \| 3,586 sq.ft.	$1,250,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.91% Airbnb Rental Income: $null Traditional Rental Income: $3941 Airbnb ROI: N/A Traditional ROI: 1.91%
74 Hunters Drive Galena, MO GREEN ACRES IS THE PLACE TO BE! Farm livin really is the life for you ---- only this isn't...	5 beds \| 3 baths \| 3,712 sq.ft.	$1,675,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.35% Airbnb Rental Income: $null Traditional Rental Income: $2708 Airbnb ROI: N/A Traditional ROI: 0.35%
103 S Main Street Galena, MO Historic Mercantile Store--- with residential penthouse living space located above the exi...	4 beds \| 2 baths \| 5,176 sq.ft.	$388,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.27% Airbnb Rental Income: $null Traditional Rental Income: $2059 Airbnb ROI: N/A Traditional ROI: 4.27%
1546 Hideaway Road Galena, MO This is the cutest lake house ever! Beautiful kitchen with granite countertops, gorgeous p...	2 beds \| 1 baths \| 864 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.13% Airbnb Rental Income: $null Traditional Rental Income: $1200 Airbnb ROI: N/A Traditional ROI: 3.13%
755 Everest Road Galena, MO Victorian Charm meets lake living! This 3 bedroom, 2.5 bath single-family home sits on app...	3 beds \| 3 baths \| 2,255 sq.ft.	$450,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.74% Airbnb Rental Income: $null Traditional Rental Income: $2604 Airbnb ROI: N/A Traditional ROI: 4.74%
79 Crystal Lane Galena, MO Welcome to quiet country living with the privacy you've been looking for, set on a little ...	2 beds \| 2 baths \| 1,275 sq.ft.	$249,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.29% Airbnb Rental Income: $null Traditional Rental Income: $1650 Airbnb ROI: N/A Traditional ROI: 5.29%
167 Overlook Road Galena, MO Spring is calling @ 167 Overlook...Welcome to a simply iconic waterfront & view lakeside c...	5 beds \| 3 baths \| 2,397 sq.ft.	$499,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.31% Airbnb Rental Income: $null Traditional Rental Income: $2660 Airbnb ROI: N/A Traditional ROI: 4.31%
1845 Sycamore Ranch Rd Galena, MO 1845 Sycamore Ranch Rd, Galena, MO 65656 \| Single Family Residential	4 beds \| 3 baths \| 2,546 sq.ft.	$699,500	Airbnb cash on cash: N/A Traditional cash on cash: 1.38% Airbnb Rental Income: $null Traditional Rental Income: $2274 Airbnb ROI: N/A Traditional ROI: 1.38%
000 State Highway Pp Galena, MO 000 State Highway Pp, Galena, MO 65656 \| Single Family Residential	N/A beds \| N/A baths \| N/A	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 0.45% Airbnb Rental Income: $null Traditional Rental Income: $438 Airbnb ROI: N/A Traditional ROI: 0.45%
11 Athens Lane Galena, MO Convenient and Complete for Country Life! Just 1.5 miles from the highway, nestled private...	5 beds \| 3 baths \| 2,880 sq.ft.	$385,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.51% Airbnb Rental Income: $null Traditional Rental Income: $2573 Airbnb ROI: N/A Traditional ROI: 5.51%
123 Half Circle Galena, MO This is it! Your one of a kind lake cabin with over 5 acres to spread out. If you like to ...	4 beds \| 3 baths \| 1,443 sq.ft.	$296,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.31% Airbnb Rental Income: $null Traditional Rental Income: $1905 Airbnb ROI: N/A Traditional ROI: 5.31%
332 Rivermeade Galena, MO Dreaming of living off the land? This 2-bedroom, 1-bath home offers the perfect start to y...	2 beds \| 1 baths \| 1,452 sq.ft.	$500,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.11% Airbnb Rental Income: $null Traditional Rental Income: $1724 Airbnb ROI: N/A Traditional ROI: 2.11%
368 Regal Hghts Lane Galena, MO Stunning 5-Bedroom Home on 10.3 Acres with Expansive Garage & Access to Golf Course and Ri...	5 beds \| 3 baths \| 3,518 sq.ft.	$599,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.05% Airbnb Rental Income: $null Traditional Rental Income: $2706 Airbnb ROI: N/A Traditional ROI: 3.05%
81 Jewell Circle Galena, MO Spring has revealed a true gem @ 81 Jewell Circle...A rare diamond on the water, this HGTV...	3 beds \| 2 baths \| 1,300 sq.ft.	$345,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.51% Airbnb Rental Income: $null Traditional Rental Income: $1904 Airbnb ROI: N/A Traditional ROI: 4.51%

Real Estate investment in Galena, MO

There are 31 properties for sale in the city of Galena . The median list price in Galena is $224,950 and the average price per square foot is $149. In February 2026, the average monthly cash on cash return in Galena is 4.00%. The average monthly rental income in Galena is $2,190.

Galena, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 31 investment properties available for sale in Galena.

In 2026, the best neighborhood to buy investment property is Galena.

The ROI for Short-Term is higher than the Long-Term in Galena with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Galena, MO

1506 Meadowview Road

Galena, MO

5 beds | 3 baths | 3,290 sq.ft.

$899,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.49%

Airbnb Rental Income: $null

Traditional Rental Income: $3136

Airbnb ROI: N/A

Traditional ROI: 2.49%

1845 Sycamore Ranch Road

Galena, MO

4 beds | 4 baths | 2,546 sq.ft.

$699,500

Airbnb cash on cash: N/A

Traditional cash on cash: 2.62%

Airbnb Rental Income: $null

Traditional Rental Income: $2979

Airbnb ROI: N/A

Traditional ROI: 2.62%

24880 State Hwy 413

Galena, MO

2 beds | 2 baths | 1,148 sq.ft.

$250,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.84%

Airbnb Rental Income: $null

Traditional Rental Income: $1497

Airbnb ROI: N/A

Traditional ROI: 4.84%

242 Weeping Willow Lane

Galena, MO

5 beds | 4 baths | 3,984 sq.ft.

$609,900

Airbnb cash on cash: N/A

Traditional cash on cash: 3.88%

Airbnb Rental Income: $null

Traditional Rental Income: $3103

Airbnb ROI: N/A

Traditional ROI: 3.88%

251 Holly Lane

Galena, MO

3 beds | 2 baths | 1,990 sq.ft.

$999,900

Airbnb cash on cash: N/A

Traditional cash on cash: 0.96%

Airbnb Rental Income: $null

Traditional Rental Income: $2077

Airbnb ROI: N/A

Traditional ROI: 0.96%

251-A Holly Lane

Galena, MO

3 beds | 2 baths | 1,990 sq.ft.

$999,900

Airbnb cash on cash: N/A

Traditional cash on cash: 1.01%

Airbnb Rental Income: $null

Traditional Rental Income: $2122

Airbnb ROI: N/A

Traditional ROI: 1.01%

251-B Holly Lane

Galena, MO

3 beds | 2 baths | 1,990 sq.ft.

$999,900

Airbnb cash on cash: N/A

Traditional cash on cash: 1.01%

Airbnb Rental Income: $null

Traditional Rental Income: $2122

Airbnb ROI: N/A

Traditional ROI: 1.01%

3030 Horsecreek Road

Galena, MO

4 beds | 3 baths | 2,800 sq.ft.

$499,995

Airbnb cash on cash: N/A

Traditional cash on cash: 4.45%

Airbnb Rental Income: $null

Traditional Rental Income: $2646

Airbnb ROI: N/A