Real Estate Investment Properties for Sale in Galena, MO

Looking for investment property in Galena, MO with high ROI ?

Explore a variety of short-term homes & houses in Galena, MO. Invest wisely with VRBO & Galena, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Galena, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1506 Meadowview Road Galena, MO Rare Opportunity to own Lakefront Living on 5 flat, quiet & pristine acres with walk to th...	5 beds \| 3 baths \| 3,487 sq.ft.	$779,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.03% Airbnb Rental Income: $null Traditional Rental Income: $3136 Airbnb ROI: N/A Traditional ROI: 3.03%
341 Dockhouse Ln Galena, MO Close to Table Rock Lake! Take your Golf Cart or Side x Side down to the lake-You are th...	N/A beds \| 1 baths \| 1,685 sq.ft.	$370,000	Airbnb cash on cash: 0.17% Traditional cash on cash: 3.22% Airbnb Rental Income: $921 Traditional Rental Income: $1640 Airbnb ROI: 0.17% Traditional ROI: 3.22%
1548 State Highway Ff Galena, MO Whether you're searching for a full-time home in the Missouri Ozarks, weekend getaway, ret...	3 beds \| N/A baths \| N/A	$230,000	Airbnb cash on cash: 4.26% Traditional cash on cash: 4.92% Airbnb Rental Income: $1762 Traditional Rental Income: $1424 Airbnb ROI: 4.26% Traditional ROI: 4.92%
546 Buttermilk Spring Road Galena, MO TABLE ROCK LAKE VIEWS \| CUSTOM 2-STORY HOME \| 2.74+/- ACRES4 Bedrooms 2.5 Baths 2,756+/- S...	4 beds \| 3 baths \| 2,800 sq.ft.	$569,477	Airbnb cash on cash: N/A Traditional cash on cash: 2.47% Airbnb Rental Income: $null Traditional Rental Income: $2195 Airbnb ROI: N/A Traditional ROI: 2.47%
30 Camp Yocum Road Galena, MO :Prettiest yard in the neighborhood! Four bedroom home sitting on 4.6 manicured acres. Per...	4 beds \| 1 baths \| 1,593 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.75% Airbnb Rental Income: $null Traditional Rental Income: $1489 Airbnb ROI: N/A Traditional ROI: 3.75%
251 Holly Lane Galena, MO The hilltop view out back off the covered deck is incredible on the primary luxury built m...	3 beds \| 2 baths \| 1,990 sq.ft.	$999,900	Airbnb cash on cash: 0.11% Traditional cash on cash: 0.96% Airbnb Rental Income: $1762 Traditional Rental Income: $2077 Airbnb ROI: 0.11% Traditional ROI: 0.96%
514 Rose Hill Lane Galena, MO LAKE VIEW! 3.76 ACRES! BOAT SLIP AVAILABLE! This is the lake house setup you've been looki...	4 beds \| 4 baths \| 3,418 sq.ft.	$675,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.85% Airbnb Rental Income: $null Traditional Rental Income: $3318 Airbnb ROI: N/A Traditional ROI: 3.85%
251-A Holly Lane Galena, MO This property now has a 2025 business license for APT !! The Surveyed 69.8 acre property h...	4 beds \| 2 baths \| 2,520 sq.ft.	$999,900	Airbnb cash on cash: N/A Traditional cash on cash: 1.01% Airbnb Rental Income: $null Traditional Rental Income: $2122 Airbnb ROI: N/A Traditional ROI: 1.01%
251-B Holly Lane Galena, MO The business license for APT is now registered with Stone County. This Surveyed 69.8 acre ...	3 beds \| 2 baths \| 1,990 sq.ft.	$999,900	Airbnb cash on cash: 0.11% Traditional cash on cash: 1.01% Airbnb Rental Income: $1762 Traditional Rental Income: $2122 Airbnb ROI: 0.11% Traditional ROI: 1.01%
32103 State Highway 413 Galena, MO Charming 75-Acre Retreat Near James RiverNestled in a peaceful, convenient location just m...	3 beds \| 1 baths \| 2,192 sq.ft.	$599,900	Airbnb cash on cash: 0.82% Traditional cash on cash: 1.87% Airbnb Rental Income: $1762 Traditional Rental Income: $1870 Airbnb ROI: 0.82% Traditional ROI: 1.87%
74 Hunters Drive Galena, MO Enjoy the perfect blend of country privacy and city convenience with all paved roads leadi...	5 beds \| 3 baths \| 3,712 sq.ft.	$1,500,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.51% Airbnb Rental Income: $null Traditional Rental Income: $2708 Airbnb ROI: N/A Traditional ROI: 0.51%
103 S Main Street Galena, MO Historic Mercantile Store--- with residential penthouse living space located above the exi...	4 beds \| 2 baths \| 5,176 sq.ft.	$388,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.27% Airbnb Rental Income: $null Traditional Rental Income: $2059 Airbnb ROI: N/A Traditional ROI: 4.27%
1546 Hideaway Road Galena, MO Gorgeous move-in-ready lake house, with slip/lift available! Beautiful open floorplan with...	2 beds \| 1 baths \| 974 sq.ft.	$275,000	Airbnb cash on cash: -0.38% Traditional cash on cash: 3.13% Airbnb Rental Income: $575 Traditional Rental Income: $1200 Airbnb ROI: -0.38% Traditional ROI: 3.13%
48 Hillsboro Drive Galena, MO Fall for panoramic lake & mountain views at 48 Hillsboro Dr! Set on over half an acre of o...	1 beds \| 1 baths \| 703 sq.ft.	$309,000	Airbnb cash on cash: 1.22% Traditional cash on cash: 3.15% Airbnb Rental Income: $1250 Traditional Rental Income: $1415 Airbnb ROI: 1.22% Traditional ROI: 3.15%
460 Sela Lane Galena, MO Hunting Oasis tucked away on 20 Wooded Acres with numerous deer and wild turkey. Close to ...	3 beds \| 3 baths \| 1,920 sq.ft.	$339,900	Airbnb cash on cash: 2.53% Traditional cash on cash: 3.47% Airbnb Rental Income: $1762 Traditional Rental Income: $1580 Airbnb ROI: 2.53% Traditional ROI: 3.47%
650 Dogwood Springs Road Galena, MO Discover exceptional country living in this stunning 4-bedroom, 2.5-bathroom home that red...	4 beds \| 3 baths \| 2,322 sq.ft.	$889,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.33% Airbnb Rental Income: $null Traditional Rental Income: $1990 Airbnb ROI: N/A Traditional ROI: 0.33%
174 Last Resort Rd Galena, MO 174 Last Resort Rd, Galena, MO 65656 \| Single Family Residential	4 beds \| 4 baths \| 3,000 sq.ft.	$995,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.27% Airbnb Rental Income: $null Traditional Rental Income: $4010 Airbnb ROI: N/A Traditional ROI: 2.27%
311 Cliffside Dr Galena, MO 311 Cliffside Dr, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$225,000	Airbnb cash on cash: 0.32% Traditional cash on cash: 1.7% Airbnb Rental Income: $921 Traditional Rental Income: $872 Airbnb ROI: 0.32% Traditional ROI: 1.7%
000 Regal Heights Ln Lot 29 Galena, MO 000 Regal Hts Lot 29, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$99,000	Airbnb cash on cash: 3.09% Traditional cash on cash: 4.47% Airbnb Rental Income: $921 Traditional Rental Income: $712 Airbnb ROI: 3.09% Traditional ROI: 4.47%
000 Regal Heights Ln Lot 44 Galena, MO 000 Regal Hts Lot 44, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$45,000	Airbnb cash on cash: 8.56% Traditional cash on cash: 5.73% Airbnb Rental Income: $921 Traditional Rental Income: $448 Airbnb ROI: 8.56% Traditional ROI: 5.73%
000 Regal Heights Ln Lot 27 Galena, MO 000 Regal Hts Lot 27, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$149,000	Airbnb cash on cash: 1.45% Traditional cash on cash: 2.39% Airbnb Rental Income: $921 Traditional Rental Income: $712 Airbnb ROI: 1.45% Traditional ROI: 2.39%
000 Regal Heights Ln Lot 30 Galena, MO 000 Regal Hts Lot 30, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$99,000	Airbnb cash on cash: 3.09% Traditional cash on cash: 4.47% Airbnb Rental Income: $921 Traditional Rental Income: $712 Airbnb ROI: 3.09% Traditional ROI: 4.47%
233 Cliffside Dr Galena, MO 233 Cliffside Dr, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$159,000	Airbnb cash on cash: 1.24% Traditional cash on cash: 0.47% Airbnb Rental Income: $921 Traditional Rental Income: $462 Airbnb ROI: 1.24% Traditional ROI: 0.47%
000 Regal Heights Ln Lot 32 Galena, MO 000 Regal Hts Lot 32, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$48,000	Airbnb cash on cash: 7.95% Traditional cash on cash: 5.28% Airbnb Rental Income: $921 Traditional Rental Income: $448 Airbnb ROI: 7.95% Traditional ROI: 5.28%
10 Acres Ice Box Cove Ln Galena, MO 10 Acres Ice Box Cove Ln, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 2,753 sq.ft.	$199,000	Airbnb cash on cash: 0.61% Traditional cash on cash: 2.86% Airbnb Rental Income: $921 Traditional Rental Income: $1004 Airbnb ROI: 0.61% Traditional ROI: 2.86%
Lot 2 Woodlands On The Lk Galena, MO Lot 2 Woodlands On The Lk, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$45,000	Airbnb cash on cash: 8.36% Traditional cash on cash: 5.84% Airbnb Rental Income: $921 Traditional Rental Income: $462 Airbnb ROI: 8.36% Traditional ROI: 5.84%
000 Lot 30 Jackson Hollow Rd Galena, MO 000 Lot 30 Jackson Hollow Rd, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$59,000	Airbnb cash on cash: 5.72% Traditional cash on cash: 3.95% Airbnb Rental Income: $921 Traditional Rental Income: $474 Airbnb ROI: 5.72% Traditional ROI: 3.95%
728 Haugwood Ranch Road Galena, MO NEW PRICE DROP!! Bring Offers!! Being Sold by Original Owners/Builders. Surveyed 39.7+/- a...	4 beds \| 3 baths \| 3,360 sq.ft.	$699,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.22% Airbnb Rental Income: $null Traditional Rental Income: $1713 Airbnb ROI: N/A Traditional ROI: 1.22%
728 Haugwood Ranch Rd Galena, MO 728 Haugwood Ranch Rd, Galena, MO 65656 \| Single Family Residential	4 beds \| 3 baths \| 3,360 sq.ft.	$699,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.41% Airbnb Rental Income: $null Traditional Rental Income: $1637 Airbnb ROI: N/A Traditional ROI: 0.41%
808 Coon Ridge Rd Galena, MO 808 Coon Ridge Rd, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| N/A	$1,950,000	Airbnb cash on cash: -1.7% Traditional cash on cash: -1.76% Airbnb Rental Income: $921 Traditional Rental Income: $462 Airbnb ROI: -1.7% Traditional ROI: -1.76%
79 Mulberry Drive Galena, MO Things just got a little sweeter this spring at Mulberry Drive.Ready to trade the noise of...	3 beds \| 2 baths \| 961 sq.ft.	$185,000	Airbnb cash on cash: 5.6% Traditional cash on cash: 6.02% Airbnb Rental Income: $1762 Traditional Rental Income: $1353 Airbnb ROI: 5.6% Traditional ROI: 6.02%
000 Long Bend Rd Galena, MO 000 Long Bend Rd, Galena, MO 65656 \| Other	N/A beds \| N/A baths \| N/A	$715,000	Airbnb cash on cash: -1.24% Traditional cash on cash: -1.31% Airbnb Rental Income: $921 Traditional Rental Income: $531 Airbnb ROI: -1.24% Traditional ROI: -1.31%
1715 Hideaway Road #G - 1 Galena, MO Your Lakefront escape awaits! Welcome to the Hideaway. Ever dreamed of a lake home that yo...	4 beds \| 2 baths \| 896 sq.ft.	$459,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.27% Airbnb Rental Income: $null Traditional Rental Income: $1581 Airbnb ROI: N/A Traditional ROI: 2.27%
1715 Hideaway Road #H -9 Galena, MO Your Lakefront escape awaits! Welcome to the Hideaway. Ever dreamed of a lake home that yo...	1 beds \| 1 baths \| 576 sq.ft.	$235,000	Airbnb cash on cash: 2.04% Traditional cash on cash: 3.33% Airbnb Rental Income: $1250 Traditional Rental Income: $1139 Airbnb ROI: 2.04% Traditional ROI: 3.33%
1715 Hideaway Road #C - 4 Galena, MO Your Lakefront escape awaits! Welcome to the Hideaway. Ever dreamed of a lake home that yo...	3 beds \| 2 baths \| 800 sq.ft.	$315,000	Airbnb cash on cash: 2.72% Traditional cash on cash: 3.11% Airbnb Rental Income: $1762 Traditional Rental Income: $1395 Airbnb ROI: 2.72% Traditional ROI: 3.11%
1715 Hideaway Road #A - 11 Galena, MO Boat Slip Included! Your Lakefront escape awaits! Welcome to the Hideaway. Ever dreamed of...	3 beds \| 2 baths \| 1,714 sq.ft.	$649,000	Airbnb cash on cash: 0.65% Traditional cash on cash: 2.25% Airbnb Rental Income: $1762 Traditional Rental Income: $2252 Airbnb ROI: 0.65% Traditional ROI: 2.25%
1715 Hideaway Road #B - 6 Galena, MO Your Lakefront escape awaits! Welcome to the Hideaway. Boat slip Included! Ever dreamed of...	3 beds \| 2 baths \| 800 sq.ft.	$345,000	Airbnb cash on cash: 0.14% Traditional cash on cash: 0.53% Airbnb Rental Income: $1762 Traditional Rental Income: $1405 Airbnb ROI: 0.14% Traditional ROI: 0.53%
1715 Hideaway Road #I-8 Galena, MO Your Lakefront escape awaits! Welcome to the Hideaway. Ever dreamed of a lake home that yo...	1 beds \| 1 baths \| 504 sq.ft.	$199,000	Airbnb cash on cash: 2.58% Traditional cash on cash: 3.95% Airbnb Rental Income: $1250 Traditional Rental Income: $1111 Airbnb ROI: 2.58% Traditional ROI: 3.95%
1715 Hideaway Road #D - 5 Galena, MO Your Lakefront escape awaits! Welcome to the Hideaway. Ever dreamed of a lake home that yo...	3 beds \| 2 baths \| 800 sq.ft.	$315,000	Airbnb cash on cash: 2.72% Traditional cash on cash: 3.68% Airbnb Rental Income: $1762 Traditional Rental Income: $1562 Airbnb ROI: 2.72% Traditional ROI: 3.68%
244 Skyline Drive Galena, MO Experience secluded, year-round lakefront living at its finest!Set on a rare 1.72-acre lak...	2 beds \| 1 baths \| 840 sq.ft.	$298,250	Airbnb cash on cash: -0.44% Traditional cash on cash: 3.13% Airbnb Rental Income: $575 Traditional Rental Income: $1292 Airbnb ROI: -0.44% Traditional ROI: 3.13%

Real Estate investment in Galena, MO

There are 90 properties for sale in the city of Galena . The median list price in Galena is $189,910 and the average price per square foot is $132. In November 2026, the average monthly cash on cash return in Galena is 3.00%. The average monthly rental income in Galena is $1,200.

Galena, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 90 investment properties available for sale in Galena.

In 2026, the best neighborhood to buy investment property is Galena.

The ROI for Long-Term is higher than the Short-Term in Galena with average rental income of $1,200.

Your search for investment property begins and ends here

Investment Property for Sale in Galena, MO

1506 Meadowview Road

Galena, MO

5 beds | 3 baths | 3,487 sq.ft.

$779,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.03%

Airbnb Rental Income: $null

Traditional Rental Income: $3136

Airbnb ROI: N/A

Traditional ROI: 3.03%

341 Dockhouse Ln

Galena, MO

N/A beds | 1 baths | 1,685 sq.ft.

$370,000

Airbnb cash on cash: 0.17%

Traditional cash on cash: 3.22%

Airbnb Rental Income: $921

Traditional Rental Income: $1640

Airbnb ROI: 0.17%

Traditional ROI: 3.22%

1548 State Highway Ff

Galena, MO

3 beds | N/A baths | N/A

$230,000

Airbnb cash on cash: 4.26%

Traditional cash on cash: 4.92%

Airbnb Rental Income: $1762

Traditional Rental Income: $1424

Airbnb ROI: 4.26%

Traditional ROI: 4.92%

546 Buttermilk Spring Road

Galena, MO

4 beds | 3 baths | 2,800 sq.ft.

$569,477

Airbnb cash on cash: N/A

Traditional cash on cash: 2.47%

Airbnb Rental Income: $null

Traditional Rental Income: $2195

Airbnb ROI: N/A

Traditional ROI: 2.47%

30 Camp Yocum Road

Galena, MO

4 beds | 1 baths | 1,593 sq.ft.

$299,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.75%

Airbnb Rental Income: $null

Traditional Rental Income: $1489

Airbnb ROI: N/A

Traditional ROI: 3.75%

251 Holly Lane

Galena, MO

3 beds | 2 baths | 1,990 sq.ft.

$999,900

Airbnb cash on cash: 0.11%

Traditional cash on cash: 0.96%

Airbnb Rental Income: $1762

Traditional Rental Income: $2077

Airbnb ROI: 0.11%

Traditional ROI: 0.96%

514 Rose Hill Lane

Galena, MO

4 beds | 4 baths | 3,418 sq.ft.

$675,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.85%

Airbnb Rental Income: $null

Traditional Rental Income: $3318

Airbnb ROI: N/A

Traditional ROI: 3.85%

251-A Holly Lane

Galena, MO

4 beds | 2 baths | 2,520 sq.ft.

$999,900

Airbnb cash on cash: N/A

Traditional cash on cash: 1.01%

Airbnb Rental Income: $null

Traditional Rental Income: $2122

Airbnb ROI: N/A