Real Estate Investment Properties for Sale in Odessa, MO

Looking for investment property in Odessa, MO with high ROI ?

Explore a variety of short-term homes & houses in Odessa, MO. Invest wisely with VRBO & Odessa, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Odessa, MO

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
12321 U Hwy Odessa, MO 12321 U Hwy, Odessa, MO 64075 \| Single Family Residential	3 beds \| 3 baths \| 3,537 sq.ft.	$699,900	Airbnb cash on cash: -0.96% Traditional cash on cash: 1.66% Airbnb Rental Income: $1124 Traditional Rental Income: $2460 Airbnb ROI: -0.96% Traditional ROI: 1.66%
7169 Newton Rd Odessa, MO 7169 Newton Rd, Odessa, MO 64075 \| Other	3 beds \| N/A baths \| N/A	$70,000	Airbnb cash on cash: 7.47% Traditional cash on cash: 7.4% Airbnb Rental Income: $1124 Traditional Rental Income: $743 Airbnb ROI: 7.47% Traditional ROI: 7.4%
511 Quail Creek Dr Odessa, MO Beautiful split entry, in excellent condition! Hard to find true 4 bedroom, 3 full bathroo...	4 beds \| 3 baths \| 1,482 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.52% Airbnb Rental Income: $null Traditional Rental Income: $2444 Airbnb ROI: N/A Traditional ROI: 7.52%
309 E Phillips St Odessa, MO Great house in charming little Odessa! Enjoy your time in the fenced back yard, or ride yo...	3 beds \| 2 baths \| 1,300 sq.ft.	$292,000	Airbnb cash on cash: 0.82% Traditional cash on cash: 4.98% Airbnb Rental Income: $1124 Traditional Rental Income: $1891 Airbnb ROI: 0.82% Traditional ROI: 4.98%
803 Ozark Short Line N/A Odessa, MO Here it is! All brick ranch with covered deck and no backyard neighbors - backs to park w...	4 beds \| 3 baths \| 2,720 sq.ft.	$339,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.49% Airbnb Rental Income: $null Traditional Rental Income: $3016 Airbnb ROI: N/A Traditional ROI: 7.49%
306 S 4th St Odessa, MO One level home has functional floor plan and is conveniently located within walking distan...	2 beds \| 1 baths \| 1,032 sq.ft.	$185,000	Airbnb cash on cash: 1.57% Traditional cash on cash: 6.16% Airbnb Rental Income: $1004 Traditional Rental Income: $1455 Airbnb ROI: 1.57% Traditional ROI: 6.16%
981 Owl Creek Pkwy Odessa, MO This true ranch has an entry that leads to the great room with vaulted ceilings and a cozy...	3 beds \| 2 baths \| 2,006 sq.ft.	$375,000	Airbnb cash on cash: 0.16% Traditional cash on cash: 4.41% Airbnb Rental Income: $1124 Traditional Rental Income: $2240 Airbnb ROI: 0.16% Traditional ROI: 4.41%
981 S 9th St Odessa, MO Beautifully updated 3 bedroom 2.5 bath home that sits on just under 7 acres WITH an amazin...	3 beds \| 2 baths \| 2,452 sq.ft.	$550,000	Airbnb cash on cash: -0.69% Traditional cash on cash: 1.96% Airbnb Rental Income: $1124 Traditional Rental Income: $2111 Airbnb ROI: -0.69% Traditional ROI: 1.96%
305 E Orchard St Odessa, MO True one level living on nearly 1 acre!! This home has a great layout, spacious rooms, and...	3 beds \| 1 baths \| 1,329 sq.ft.	$200,000	Airbnb cash on cash: 1.49% Traditional cash on cash: 6.6% Airbnb Rental Income: $1124 Traditional Rental Income: $1718 Airbnb ROI: 1.49% Traditional ROI: 6.6%
623 W Mason St Odessa, MO 623 W Mason St, Odessa, MO 64076 \| Single Family Residential	3 beds \| 2 baths \| 2,004 sq.ft.	$274,900	Airbnb cash on cash: 0.57% Traditional cash on cash: 6.16% Airbnb Rental Income: $1124 Traditional Rental Income: $2198 Airbnb ROI: 0.57% Traditional ROI: 6.16%
510 Opera House Ln Odessa, MO 510 Opera House Ln, Odessa, MO 64076 \| Single Family Residential	4 beds \| 4 baths \| 3,476 sq.ft.	$595,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.75% Airbnb Rental Income: $null Traditional Rental Income: $3269 Airbnb ROI: N/A Traditional ROI: 3.75%
114 S Johnson Dr Odessa, MO 114 S Johnson Dr, Odessa, MO 64076 \| Single Family Residential	3 beds \| 2 baths \| 1,302 sq.ft.	$308,900	Airbnb cash on cash: 0.29% Traditional cash on cash: 4.04% Airbnb Rental Income: $1124 Traditional Rental Income: $1838 Airbnb ROI: 0.29% Traditional ROI: 4.04%
Tract 2 Highway OO Hwy Odessa, MO Tract 2 Highway OO Hwy, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$199,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.89% Airbnb Rental Income: $null Traditional Rental Income: $820 Airbnb ROI: N/A Traditional ROI: 1.89%
Tract 3 Highway OO Hwy Odessa, MO Tract 3 Highway OO Hwy, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$189,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.89% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 1.89%
Tract 1 Highway OO Hwy Odessa, MO Tract 1 Highway OO Hwy, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$199,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.7% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 1.7%
Tract 5 Highway OO Hwy Odessa, MO Tract 5 Highway OO Hwy, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$189,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.89% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 1.89%
Tract 6 Highway OO Hwy Odessa, MO Tract 6 Highway OO Hwy, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$189,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.89% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 1.89%
Tract 7 Highway OO Hwy Odessa, MO Tract 7 Highway OO Hwy, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$189,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.89% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 1.89%
710 W Mason St Odessa, MO 710 W Mason St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$69,500	Airbnb cash on cash: N/A Traditional cash on cash: 8.07% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 8.07%
Lot 3 E Park Ln Odessa, MO Lot 3 E Park Ln, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$50,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.75% Airbnb Rental Income: $null Traditional Rental Income: $790 Airbnb ROI: N/A Traditional ROI: 11.75%
24 Marlow St Odessa, MO 24 Marlow St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$72,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.57% Airbnb Rental Income: $null Traditional Rental Income: $791 Airbnb ROI: N/A Traditional ROI: 7.57%
7 Cobb Cir Odessa, MO 7 Cobb Cir, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$68,500	Airbnb cash on cash: N/A Traditional cash on cash: 8% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 8%
Lot 5 E Park Ln Odessa, MO Lot 5 E Park Ln, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$70,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.08% Airbnb Rental Income: $null Traditional Rental Income: $790 Airbnb ROI: N/A Traditional ROI: 8.08%
60.26AC Reich Rd Odessa, MO 60.26AC Reich Rd, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$2,624,925	Airbnb cash on cash: N/A Traditional cash on cash: -1.68% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: -1.68%
Lot 14 E Spring Cir Odessa, MO Lot 14 E Spring Cir, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$65,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.8% Airbnb Rental Income: $null Traditional Rental Income: $790 Airbnb ROI: N/A Traditional ROI: 8.8%
Lot 13 E Spring Cir Odessa, MO Lot 13 E Spring Cir, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$65,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.7% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 8.7%
Lot 12 E Spring Cir Odessa, MO Lot 12 E Spring Cir, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$65,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.7% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 8.7%
Lot 11 E Spring Cir Odessa, MO Lot 11 E Spring Cir, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$65,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.7% Airbnb Rental Income: $null Traditional Rental Income: $784 Airbnb ROI: N/A Traditional ROI: 8.7%
Lot 6 E Park Ln Odessa, MO Lot 6 E Park Ln, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$70,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.08% Airbnb Rental Income: $null Traditional Rental Income: $790 Airbnb ROI: N/A Traditional ROI: 8.08%
Lot 2 Wells St Odessa, MO Lot 2 Wells St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$95,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.63% Airbnb Rental Income: $null Traditional Rental Income: $888 Airbnb ROI: N/A Traditional ROI: 6.63%
25 Lake View Rd Odessa, MO 25 Lake View Rd, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$80,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.2% Airbnb Rental Income: $null Traditional Rental Income: $828 Airbnb ROI: N/A Traditional ROI: 7.2%
23 Marlow St Odessa, MO 23 Marlow St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$72,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.57% Airbnb Rental Income: $null Traditional Rental Income: $791 Airbnb ROI: N/A Traditional ROI: 7.57%
22 Marlow St Odessa, MO 22 Marlow St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$72,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.57% Airbnb Rental Income: $null Traditional Rental Income: $791 Airbnb ROI: N/A Traditional ROI: 7.57%
21 Marlow St Odessa, MO 21 Marlow St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$73,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.47% Airbnb Rental Income: $null Traditional Rental Income: $792 Airbnb ROI: N/A Traditional ROI: 7.47%
20 Marlow St Odessa, MO 20 Marlow St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$75,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.28% Airbnb Rental Income: $null Traditional Rental Income: $792 Airbnb ROI: N/A Traditional ROI: 7.28%
19 Marlow St Odessa, MO 19 Marlow St, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$75,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.53% Airbnb Rental Income: $null Traditional Rental Income: $884 Airbnb ROI: N/A Traditional ROI: 8.53%
17 Lake View Rd Odessa, MO 17 Lake View Rd, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$75,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.23% Airbnb Rental Income: $null Traditional Rental Income: $792 Airbnb ROI: N/A Traditional ROI: 7.23%
16 Lake View Rd Odessa, MO 16 Lake View Rd, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$73,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.46% Airbnb Rental Income: $null Traditional Rental Income: $791 Airbnb ROI: N/A Traditional ROI: 7.46%
15 Lake View Rd Odessa, MO 15 Lake View Rd, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$73,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.46% Airbnb Rental Income: $null Traditional Rental Income: $791 Airbnb ROI: N/A Traditional ROI: 7.46%
14 Lake View Rd Odessa, MO 14 Lake View Rd, Odessa, MO 64076 \| Other	N/A beds \| N/A baths \| N/A	$75,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.28% Airbnb Rental Income: $null Traditional Rental Income: $792 Airbnb ROI: N/A Traditional ROI: 7.28%

Real Estate investment in Odessa, MO

There are 115 properties for sale in the city of Odessa . The median list price in Odessa is $292,825 and the average price per square foot is $135. In October 2026, the average monthly cash on cash return in Odessa is 6.00%. The average monthly rental income in Odessa is $1,481.

Odessa, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 115 investment properties available for sale in Odessa.

In 2026, the best neighborhood to buy investment property is Odessa.

The ROI for Short-Term is higher than the Long-Term in Odessa with average rental income of $1,124.

Your search for investment property begins and ends here

Investment Property for Sale in Odessa, MO

12321 U Hwy

Odessa, MO

3 beds | 3 baths | 3,537 sq.ft.

$699,900

Airbnb cash on cash: -0.96%

Traditional cash on cash: 1.66%

Airbnb Rental Income: $1124

Traditional Rental Income: $2460

Airbnb ROI: -0.96%

Traditional ROI: 1.66%

7169 Newton Rd

Odessa, MO

3 beds | N/A baths | N/A

$70,000

Airbnb cash on cash: 7.47%

Traditional cash on cash: 7.4%

Airbnb Rental Income: $1124

Traditional Rental Income: $743

Airbnb ROI: 7.47%

Traditional ROI: 7.4%

511 Quail Creek Dr

Odessa, MO

4 beds | 3 baths | 1,482 sq.ft.

$275,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.52%

Airbnb Rental Income: $null

Traditional Rental Income: $2444

Airbnb ROI: N/A

Traditional ROI: 7.52%

309 E Phillips St

Odessa, MO

3 beds | 2 baths | 1,300 sq.ft.

$292,000

Airbnb cash on cash: 0.82%

Traditional cash on cash: 4.98%

Airbnb Rental Income: $1124

Traditional Rental Income: $1891

Airbnb ROI: 0.82%

Traditional ROI: 4.98%

803 Ozark Short Line N/A

Odessa, MO

4 beds | 3 baths | 2,720 sq.ft.

$339,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.49%

Airbnb Rental Income: $null

Traditional Rental Income: $3016

Airbnb ROI: N/A

Traditional ROI: 7.49%

306 S 4th St

Odessa, MO

2 beds | 1 baths | 1,032 sq.ft.

$185,000

Airbnb cash on cash: 1.57%

Traditional cash on cash: 6.16%

Airbnb Rental Income: $1004

Traditional Rental Income: $1455

Airbnb ROI: 1.57%

Traditional ROI: 6.16%

981 Owl Creek Pkwy

Odessa, MO

3 beds | 2 baths | 2,006 sq.ft.

$375,000

Airbnb cash on cash: 0.16%

Traditional cash on cash: 4.41%

Airbnb Rental Income: $1124

Traditional Rental Income: $2240

Airbnb ROI: 0.16%

Traditional ROI: 4.41%

981 S 9th St

Odessa, MO

3 beds | 2 baths | 2,452 sq.ft.

$550,000

Airbnb cash on cash: -0.69%

Traditional cash on cash: 1.96%

Airbnb Rental Income: $1124

Traditional Rental Income: $2111

Airbnb ROI: -0.69%