Real Estate Investment Properties for Sale in Perryville, MO

Looking for investment property in Perryville, MO with high ROI ?

Explore a variety of short-term homes & houses in Perryville, MO. Invest wisely with VRBO & Perryville, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Perryville, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
138 Brookline Dr Perryville, MO New Listing! Located just south of Perryville in Tanglewood sits this secluded yet close t...	3 beds \| 2 baths \| 2,024 sq.ft.	$279,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.34% Airbnb Rental Income: $null Traditional Rental Income: $1908 Airbnb ROI: N/A Traditional ROI: 5.34%
520 Christopher Dr Perryville, MO This impressive lakefront home is located at Twin Lakes, a quaint, private lake community,...	3 beds \| 2 baths \| 2,413 sq.ft.	$369,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.7% Airbnb Rental Income: $null Traditional Rental Income: $2602 Airbnb ROI: N/A Traditional ROI: 5.7%
1841 N Main St Perryville, MO Are you searching for a stately all-Brick estate on 11.43 acres with luxurious amenities a...	4 beds \| 5 baths \| 5,886 sq.ft.	$1,395,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.42% Airbnb Rental Income: $null Traditional Rental Income: $6268 Airbnb ROI: N/A Traditional ROI: 3.42%
1002 Port Perry Dr Perryville, MO 1002 Port Perry Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$59,900	Airbnb cash on cash: -5.27% Traditional cash on cash: 7.14% Airbnb Rental Income: $201 Traditional Rental Income: $724 Airbnb ROI: -5.27% Traditional ROI: 7.14%
1 Perryville Blvd Perryville, MO 1 Perryville Blvd, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$607,464	Airbnb cash on cash: -2.16% Traditional cash on cash: -0.85% Airbnb Rental Income: $201 Traditional Rental Income: $724 Airbnb ROI: -2.16% Traditional ROI: -0.85%
221 W Saint Joseph St Perryville, MO 221 W Saint Joseph St, Perryville, MO 63775 \| Single Family Residential	6 beds \| 4 baths \| 3,143 sq.ft.	$560,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.67% Airbnb Rental Income: $null Traditional Rental Income: $3565 Airbnb ROI: N/A Traditional ROI: 4.67%
456 Pcr 740 Perryville, MO 456 Pcr 740, Perryville, MO 63775 \| Single Family Residential	1 beds \| N/A baths \| 0 sq.ft.	$179,999	Airbnb cash on cash: 0.76% Traditional cash on cash: 2.67% Airbnb Rental Income: $897 Traditional Rental Income: $886 Airbnb ROI: 0.76% Traditional ROI: 2.67%
10289 Highway J Perryville, MO 10289 Highway J, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,672 sq.ft.	$379,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.19% Airbnb Rental Income: $null Traditional Rental Income: $1572 Airbnb ROI: N/A Traditional ROI: 2.19%
Off of Woodridge Ln Perryville, MO Off of Woodridge Ln, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$70,000	Airbnb cash on cash: -3.8% Traditional cash on cash: 6.94% Airbnb Rental Income: $201 Traditional Rental Income: $724 Airbnb ROI: -3.8% Traditional ROI: 6.94%
1744 Pcr 710 Perryville, MO 1744 Pcr 710, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$220,000	Airbnb cash on cash: -2.51% Traditional cash on cash: 1.4% Airbnb Rental Income: $201 Traditional Rental Income: $793 Airbnb ROI: -2.51% Traditional ROI: 1.4%
2010 Port Perry Dr Perryville, MO 2010 Port Perry Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$255,000	Airbnb cash on cash: -2.83% Traditional cash on cash: 0.49% Airbnb Rental Income: $201 Traditional Rental Income: $778 Airbnb ROI: -2.83% Traditional ROI: 0.49%
5137 N View Dr Perryville, MO 5137 N View Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$190,000	Airbnb cash on cash: -3.12% Traditional cash on cash: 2.27% Airbnb Rental Income: $201 Traditional Rental Income: $951 Airbnb ROI: -3.12% Traditional ROI: 2.27%
1512 Old St Mary's Rd Perryville, MO 1512 Old St Mary's Rd, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,727 sq.ft.	$585,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.78% Airbnb Rental Income: $null Traditional Rental Income: $1593 Airbnb ROI: N/A Traditional ROI: 0.78%
1037 Tanglewood Trl Perryville, MO 1037 Tanglewood Trl, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$59,900	Airbnb cash on cash: -5.23% Traditional cash on cash: 6.42% Airbnb Rental Income: $201 Traditional Rental Income: $734 Airbnb ROI: -5.23% Traditional ROI: 6.42%
Off Pcr 210 Perryville, MO Off Pcr 210, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$2,432,500	Airbnb cash on cash: -2.02% Traditional cash on cash: -1.65% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -2.02% Traditional ROI: -1.65%
25 Tyler Br Perryville, MO 25 Tyler Br, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$50,000	Airbnb cash on cash: -4.73% Traditional cash on cash: 11.46% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -4.73% Traditional ROI: 11.46%
1 Cinque Hommes Dr Perryville, MO 1 Cinque Hommes Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$225,000	Airbnb cash on cash: -2.5% Traditional cash on cash: 1.37% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -2.5% Traditional ROI: 1.37%
0 Highway 51 Perryville, MO 0 Highway 51, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$540,330	Airbnb cash on cash: -2.19% Traditional cash on cash: -0.56% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -2.19% Traditional ROI: -0.56%
0 Lot 12 Redbud Ct Perryville, MO 0 Lot 12 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$54,000	Airbnb cash on cash: -4.05% Traditional cash on cash: 11.13% Airbnb Rental Income: $201 Traditional Rental Income: $808 Airbnb ROI: -4.05% Traditional ROI: 11.13%
1648 Redbud Ct Perryville, MO 1648 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$54,000	Airbnb cash on cash: -4.05% Traditional cash on cash: 11.13% Airbnb Rental Income: $201 Traditional Rental Income: $808 Airbnb ROI: -4.05% Traditional ROI: 11.13%
1654 Redbud Ct Perryville, MO 1654 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$51,300	Airbnb cash on cash: -4.13% Traditional cash on cash: 11.78% Airbnb Rental Income: $201 Traditional Rental Income: $808 Airbnb ROI: -4.13% Traditional ROI: 11.78%
1662 Redbud Ct Perryville, MO 1662 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$56,700	Airbnb cash on cash: -3.95% Traditional cash on cash: 10.48% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -3.95% Traditional ROI: 10.48%
1660 Redbud Ct Perryville, MO 1660 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$54,000	Airbnb cash on cash: -4.05% Traditional cash on cash: 9.87% Airbnb Rental Income: $201 Traditional Rental Income: $739 Airbnb ROI: -4.05% Traditional ROI: 9.87%
1656 Redbud Ct Perryville, MO 1656 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$51,300	Airbnb cash on cash: -4.13% Traditional cash on cash: 11.78% Airbnb Rental Income: $201 Traditional Rental Income: $808 Airbnb ROI: -4.13% Traditional ROI: 11.78%
1650 Redbud Ct Perryville, MO 1650 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$49,950	Airbnb cash on cash: -4.19% Traditional cash on cash: 10.78% Airbnb Rental Income: $201 Traditional Rental Income: $740 Airbnb ROI: -4.19% Traditional ROI: 10.78%
1645 Redbud Ct Perryville, MO 1645 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$51,300	Airbnb cash on cash: -4.13% Traditional cash on cash: 11.78% Airbnb Rental Income: $201 Traditional Rental Income: $808 Airbnb ROI: -4.13% Traditional ROI: 11.78%
1655 Redbud Ct Perryville, MO 1655 Redbud Ct, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$45,450	Airbnb cash on cash: -4.4% Traditional cash on cash: 11.9% Airbnb Rental Income: $201 Traditional Rental Income: $740 Airbnb ROI: -4.4% Traditional ROI: 11.9%
34 Missouri Ln Perryville, MO Located just outside the city limits of Perryville, this all-brick 3 bedroom, 2 bath home ...	3 beds \| 2 baths \| 2,290 sq.ft.	$449,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.59% Airbnb Rental Income: $null Traditional Rental Income: $2198 Airbnb ROI: N/A Traditional ROI: 3.59%
5031 Port Perry Dr Perryville, MO 5031 Port Perry Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$52,000	Airbnb cash on cash: -5.73% Traditional cash on cash: 9.89% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -5.73% Traditional ROI: 9.89%
Lot #6 Pcr 910 Perryville, MO Lot #6 Pcr 910, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$140,250	Airbnb cash on cash: -2.81% Traditional cash on cash: 3.32% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -2.81% Traditional ROI: 3.32%
7633 Highway F Perryville, MO Beautiful all-brick home situated on 9 acres in Perry County, offering the perfect blend o...	3 beds \| 3 baths \| 1,632 sq.ft.	$780,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.43% Airbnb Rental Income: $null Traditional Rental Income: $2118 Airbnb ROI: N/A Traditional ROI: 1.43%
24 S Walnut St Perryville, MO Step into timeless charm with this stunning story-and-half Victorian home located in the h...	4 beds \| 2 baths \| 2,180 sq.ft.	$179,500	Airbnb cash on cash: N/A Traditional cash on cash: 11.28% Airbnb Rental Income: $null Traditional Rental Income: $2313 Airbnb ROI: N/A Traditional ROI: 11.28%
97 Pcr 522 Perryville, MO 97 Pcr 522, Perryville, MO 63775 \| Single Family Residential	5 beds \| 3 baths \| 3,090 sq.ft.	$825,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.94% Airbnb Rental Income: $null Traditional Rental Income: $2324 Airbnb ROI: N/A Traditional ROI: 0.94%
2898 Pcr 856 Perryville, MO 4 Major Highlights: â¢ 4.44 Acre Lot in Lake Perry Farms and part of the Lake Perry Comm...	4 beds \| 2 baths \| 2,828 sq.ft.	$274,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.99% Airbnb Rental Income: $null Traditional Rental Income: $2598 Airbnb ROI: N/A Traditional ROI: 6.99%
697 Parkers Lake Dr Perryville, MO 697 Parkers Lake Dr, Perryville, MO 63775 \| Single Family Residential	2 beds \| 1 baths \| 900 sq.ft.	$140,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.35% Airbnb Rental Income: $null Traditional Rental Income: $805 Airbnb ROI: N/A Traditional ROI: 3.35%
1036 Erie Trail Dr Perryville, MO 1036 Erie Trail Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$89,000	Airbnb cash on cash: -4.35% Traditional cash on cash: 5.44% Airbnb Rental Income: $201 Traditional Rental Income: $831 Airbnb ROI: -4.35% Traditional ROI: 5.44%
Lot 6 Dreamz Estate Dr Perryville, MO	N/A beds \| N/A baths \| N/A	$73,000	Airbnb cash on cash: -3.92% Traditional cash on cash: 7.49% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -3.92% Traditional ROI: 7.49%
Lot #7 Pcr 910 Perryville, MO Lot #7 Pcr 910, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$136,000	Airbnb cash on cash: -2.83% Traditional cash on cash: 3.48% Airbnb Rental Income: $201 Traditional Rental Income: $803 Airbnb ROI: -2.83% Traditional ROI: 3.48%
16482 Highway T Perryville, MO 16482 Highway T, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,848 sq.ft.	$282,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.81% Airbnb Rental Income: $null Traditional Rental Income: $1627 Airbnb ROI: N/A Traditional ROI: 3.81%
Off Pcr 914 Perryville, MO Off Pcr 914, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$144,960	Airbnb cash on cash: -2.78% Traditional cash on cash: 3.36% Airbnb Rental Income: $201 Traditional Rental Income: $831 Airbnb ROI: -2.78% Traditional ROI: 3.36%

Real Estate investment in Perryville, MO

There are 43 properties for sale in the city of Perryville . The median list price in Perryville is $138,000 and the average price per square foot is $87. In May 2026, the average monthly cash on cash return in Perryville is 7.00%. The average monthly rental income in Perryville is $831.

Perryville, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 43 investment properties available for sale in Perryville.

In 2026, the best neighborhood to buy investment property is Perryville.

The ROI for Long-Term is higher than the Short-Term in Perryville with average rental income of $831.

Your search for investment property begins and ends here

Investment Property for Sale in Perryville, MO

138 Brookline Dr

Perryville, MO

3 beds | 2 baths | 2,024 sq.ft.

$279,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.34%

Airbnb Rental Income: $null

Traditional Rental Income: $1908

Airbnb ROI: N/A

Traditional ROI: 5.34%

520 Christopher Dr

Perryville, MO

3 beds | 2 baths | 2,413 sq.ft.

$369,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.7%

Airbnb Rental Income: $null

Traditional Rental Income: $2602

Airbnb ROI: N/A

Traditional ROI: 5.7%

1841 N Main St

Perryville, MO

4 beds | 5 baths | 5,886 sq.ft.

$1,395,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.42%

Airbnb Rental Income: $null

Traditional Rental Income: $6268

Airbnb ROI: N/A

Traditional ROI: 3.42%

1002 Port Perry Dr

Perryville, MO

N/A beds | N/A baths | 0 sq.ft.

$59,900

Airbnb cash on cash: -5.27%

Traditional cash on cash: 7.14%

Airbnb Rental Income: $201

Traditional Rental Income: $724

Airbnb ROI: -5.27%

Traditional ROI: 7.14%

1 Perryville Blvd

Perryville, MO

N/A beds | N/A baths | 0 sq.ft.

$607,464

Airbnb cash on cash: -2.16%

Traditional cash on cash: -0.85%

Airbnb Rental Income: $201

Traditional Rental Income: $724

Airbnb ROI: -2.16%

Traditional ROI: -0.85%

221 W Saint Joseph St

Perryville, MO

6 beds | 4 baths | 3,143 sq.ft.

$560,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.67%

Airbnb Rental Income: $null

Traditional Rental Income: $3565

Airbnb ROI: N/A

Traditional ROI: 4.67%

456 Pcr 740

Perryville, MO

1 beds | N/A baths | 0 sq.ft.

$179,999

Airbnb cash on cash: 0.76%

Traditional cash on cash: 2.67%

Airbnb Rental Income: $897

Traditional Rental Income: $886

Airbnb ROI: 0.76%

Traditional ROI: 2.67%

10289 Highway J

Perryville, MO

3 beds | 2 baths | 1,672 sq.ft.

$379,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.19%

Airbnb Rental Income: $null

Traditional Rental Income: $1572

Airbnb ROI: N/A