Real Estate Investment Properties for Sale in Poplar Bluff, MO

Looking for investment property in Poplar Bluff, MO with high ROI ?

Explore a variety of short-term homes & houses in Poplar Bluff, MO. Invest wisely with VRBO & Poplar Bluff, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Poplar Bluff, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
501 N 16th Street Poplar Bluff, MO Check out this recently remodeled 4 bed, 3 1/2 bath home! This home is conveniently locate...	4 beds \| 4 baths \| 2,520 sq.ft.	$215,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.96% Airbnb Rental Income: $null Traditional Rental Income: $2837 Airbnb ROI: N/A Traditional ROI: 11.96%
108 Mayson Lane Poplar Bluff, MO $199,900; 108 Mayson Ln, Poplar Bluff, MO 63901; Discover the perfect blend of comfort and...	3 beds \| 2 baths \| 1,527 sq.ft.	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.75% Airbnb Rental Income: $null Traditional Rental Income: $1867 Airbnb ROI: N/A Traditional ROI: 7.75%
2006 Holloway Drive Poplar Bluff, MO Beautifully renovated/ completely remodeled, 4-bedroom, 3-bath brick home on a corner lot ...	4 beds \| 3 baths \| 2,410 sq.ft.	$269,900	Airbnb cash on cash: N/A Traditional cash on cash: 8% Airbnb Rental Income: $null Traditional Rental Income: $2503 Airbnb ROI: N/A Traditional ROI: 8%
425 Davis Street Poplar Bluff, MO Step inside this fully remodeled 3-bedroom, 2-bath home designed with quality and comfort ...	3 beds \| 2 baths \| 1,196 sq.ft.	$124,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.53% Airbnb Rental Income: $null Traditional Rental Income: $1552 Airbnb ROI: N/A Traditional ROI: 10.53%
199 Edna Lane Poplar Bluff, MO Welcome to this spacious 2,428 sq ft +/- home offering 5 bedrooms and 3 bathrooms, perfect...	5 beds \| 3 baths \| 2,428 sq.ft.	$299,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.1% Airbnb Rental Income: $null Traditional Rental Income: $2469 Airbnb ROI: N/A Traditional ROI: 7.1%
1172 Hwy NN Poplar Bluff, MO BONUS OPPORTUNITY: An Additional adjacent acre with a second home is available for purchas...	4 beds \| 3 baths \| 2,770 sq.ft.	$378,999	Airbnb cash on cash: N/A Traditional cash on cash: 5.75% Airbnb Rental Income: $null Traditional Rental Income: $2636 Airbnb ROI: N/A Traditional ROI: 5.75%
716 Ethel Street Poplar Bluff, MO Move-in-ready home that will pass USDA, VA, and FHA loan requirements! This 3-bedroom (pos...	3 beds \| 2 baths \| 1,286 sq.ft.	$124,900	Airbnb cash on cash: N/A Traditional cash on cash: 11.77% Airbnb Rental Income: $null Traditional Rental Income: $1676 Airbnb ROI: N/A Traditional ROI: 11.77%
2700 Holly Trail Poplar Bluff, MO This impressive brick quadplex is situated just north of Poplar Bluff, conveniently positi...	N/A beds \| N/A baths \| N/A	$330,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.73% Airbnb Rental Income: $null Traditional Rental Income: $1405 Airbnb ROI: N/A Traditional ROI: 2.73%
42 County Road 5651 Poplar Bluff, MO Nicely remodeled 4-bed, 1.75 bath home on appx. .78 acre m/l, open floor plan, stainless a...	4 beds \| 2 baths \| 1,196 sq.ft.	$134,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.21% Airbnb Rental Income: $null Traditional Rental Income: $1322 Airbnb ROI: N/A Traditional ROI: 8.21%
2125 Barron Road Poplar Bluff, MO Stunning Remodeled Home on Almost an Acre â North Town Location! 4 Bed \| 2 Bath \| 2,626 ...	4 beds \| 2 baths \| 2,626 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.84% Airbnb Rental Income: $null Traditional Rental Income: $2345 Airbnb ROI: N/A Traditional ROI: 7.84%
109 Lanee Lane Poplar Bluff, MO Like new 4 bedroom, 2 bath home on nice 0.4 +/- acre lot adjoining large wooded tract. Gre...	4 beds \| 2 baths \| 1,979 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.95% Airbnb Rental Income: $null Traditional Rental Income: $2240 Airbnb ROI: N/A Traditional ROI: 5.95%
1824 Seifert Drive Poplar Bluff, MO Charming, Updated Home in the Heart of Poplar BluffWelcome to this inviting 2-bedroom, 1-b...	2 beds \| 1 baths \| 800 sq.ft.	$125,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.28% Airbnb Rental Income: $null Traditional Rental Income: $1012 Airbnb ROI: N/A Traditional ROI: 6.28%
2911 Oak Grove Road Poplar Bluff, MO Location, location, location! This property offers endless possibilities with C-2 commerci...	4 beds \| 2 baths \| 1,792 sq.ft.	$449,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.4% Airbnb Rental Income: $null Traditional Rental Income: $2053 Airbnb ROI: N/A Traditional ROI: 3.4%
125 Lanee Lane Poplar Bluff, MO Built in 2022, this 4 bedroom, 2 bath home in Magnolia Lane Subdivision offers 2,036 sq ft...	4 beds \| 2 baths \| 2,000 sq.ft.	$299,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.04% Airbnb Rental Income: $null Traditional Rental Income: $1980 Airbnb ROI: N/A Traditional ROI: 5.04%
1816 W Maud Street Poplar Bluff, MO Well-designed 3-bedroom, 1-bath home featuring a functional layout that offers flexibility...	3 beds \| 1 baths \| 1,280 sq.ft.	$69,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.58% Airbnb Rental Income: $null Traditional Rental Income: $921 Airbnb ROI: N/A Traditional ROI: 10.58%
1021 Ivadene Drive Poplar Bluff, MO Check out this freshly remodeled 5 bedroom, 2 bath house in the heart of Poplar Bluff! Al...	5 beds \| 2 baths \| 2,222 sq.ft.	$186,700	Airbnb cash on cash: N/A Traditional cash on cash: 9.47% Airbnb Rental Income: $null Traditional Rental Income: $2007 Airbnb ROI: N/A Traditional ROI: 9.47%
696 Radcliff Lane Poplar Bluff, MO Stunning updated home on 5 scenic fenced acres with private lake access. Discover peaceful...	3 beds \| 3 baths \| 2,420 sq.ft.	$457,200	Airbnb cash on cash: N/A Traditional cash on cash: 1.47% Airbnb Rental Income: $null Traditional Rental Income: $1266 Airbnb ROI: N/A Traditional ROI: 1.47%
647 County Road 470 Poplar Bluff, MO Lot size to be 4 acres m/l from a larger tract. Great location for this 3 bedroom (could b...	3 beds \| 2 baths \| 2,063 sq.ft.	$299,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.34% Airbnb Rental Income: $null Traditional Rental Income: $2271 Airbnb ROI: N/A Traditional ROI: 6.34%
112 Mayson Lane Poplar Bluff, MO New construction 3 bedroom, 2.5 bath home. This subdivision is designed for people looking...	3 beds \| 3 baths \| 1,545 sq.ft.	$206,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.41% Airbnb Rental Income: $null Traditional Rental Income: $1864 Airbnb ROI: N/A Traditional ROI: 7.41%
2548 Stone Ridge Drive Poplar Bluff, MO Stately Brick Home in the north end of town, located on 1.11 Acres M/L. Timeless elegance ...	5 beds \| 5 baths \| 6,238 sq.ft.	$549,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.4% Airbnb Rental Income: $null Traditional Rental Income: $4297 Airbnb ROI: N/A Traditional ROI: 6.4%
547 County Road 448 Poplar Bluff, MO This is a one of a kind property. This can be a multi-family home, a single family home or...	4 beds \| 4 baths \| 4,364 sq.ft.	$440,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.88% Airbnb Rental Income: $null Traditional Rental Income: $3501 Airbnb ROI: N/A Traditional ROI: 6.88%
938 Poplar Street Poplar Bluff, MO Built in 1905 and beautifully restored, this three-bedroom home is a rare blend of histori...	3 beds \| 2 baths \| 2,031 sq.ft.	$250,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.19% Airbnb Rental Income: $null Traditional Rental Income: $1836 Airbnb ROI: N/A Traditional ROI: 6.19%
1301 Lurlyn Drive Poplar Bluff, MO Discover a refined country feeling right in the heart of town in this beautifully crafted ...	5 beds \| 4 baths \| 3,915 sq.ft.	$549,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.37% Airbnb Rental Income: $null Traditional Rental Income: $3192 Airbnb ROI: N/A Traditional ROI: 4.37%
5711 Cedar Valley Drive Poplar Bluff, MO This may be the one you've been looking for! Many upgrades to this 3 bedroom, 2 bath home ...	3 beds \| 2 baths \| 1,715 sq.ft.	$219,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.21% Airbnb Rental Income: $null Traditional Rental Income: $1693 Airbnb ROI: N/A Traditional ROI: 6.21%
2025 Wasson Drive Poplar Bluff, MO Spacious and well-maintained 5-bedroom, brick home, featuring 1.75 baths and a comfortable...	5 beds \| 2 baths \| 2,020 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.64% Airbnb Rental Income: $null Traditional Rental Income: $1937 Airbnb ROI: N/A Traditional ROI: 8.64%
1043 Hwy AA Poplar Bluff, MO Looking for a great investment! Nice brick home with 4 income producing rentals on this pr...	3 beds \| 2 baths \| 1,388 sq.ft.	$239,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.14% Airbnb Rental Income: $null Traditional Rental Income: $1704 Airbnb ROI: N/A Traditional ROI: 5.14%
3031 Saddlebrook Trail Poplar Bluff, MO Welcome to this lovely 3 bedroom, 2 bath home in the Still Creek Crossing Subdivision! Loc...	3 beds \| 2 baths \| 1,780 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.84% Airbnb Rental Income: $null Traditional Rental Income: $2174 Airbnb ROI: N/A Traditional ROI: 6.84%
816 Kendall Avenue Poplar Bluff, MO Super Cute 2-bedroom, 1-bath home with a carport and a shed, which sits on a double lot.	2 beds \| 1 baths \| 1,065 sq.ft.	$127,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.28% Airbnb Rental Income: $null Traditional Rental Income: $1262 Airbnb ROI: N/A Traditional ROI: 8.28%
225 S 6th Street Poplar Bluff, MO Built in 1917, the Corrigan House is a distinguished Neocolonial-style home listed on the ...	5 beds \| 4 baths \| 6,749 sq.ft.	$425,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.6% Airbnb Rental Income: $null Traditional Rental Income: $4055 Airbnb ROI: N/A Traditional ROI: 8.6%
542 County Road 323 Poplar Bluff, MO Discover the perfect blend of comfort and country living with this stunning 4-bedroom, 3.5...	4 beds \| 4 baths \| 2,312 sq.ft.	$269,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.74% Airbnb Rental Income: $null Traditional Rental Income: $2807 Airbnb ROI: N/A Traditional ROI: 8.74%
46 Red Cedar Boulevard Poplar Bluff, MO Adorable house with charm and character! This delightful 3-bedroom, 2-bath home blends tim...	3 beds \| 2 baths \| 1,560 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.64% Airbnb Rental Income: $null Traditional Rental Income: $1835 Airbnb ROI: N/A Traditional ROI: 10.64%
2011 Woodland Road Poplar Bluff, MO $155,000 - 2011 Woodland Rd, Poplar Bluff, MO 63901. 3 bedroom, 1 bath, family room, 2 car...	3 beds \| 1 baths \| 1,497 sq.ft.	$155,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.91% Airbnb Rental Income: $null Traditional Rental Income: $1494 Airbnb ROI: N/A Traditional ROI: 7.91%
269 Berkshire Drive Poplar Bluff, MO This new construction 4 bedroom 2.5 bath home located in Legacy Estates will feature custo...	4 beds \| 3 baths \| 2,280 sq.ft.	$369,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.58% Airbnb Rental Income: $null Traditional Rental Income: $2746 Airbnb ROI: N/A Traditional ROI: 6.58%
61 County Road 4705 Poplar Bluff, MO $199,900. 61 County Road 4705, Poplar Bluff, MO 63901. Located on a quiet, dead-end street...	3 beds \| 2 baths \| 1,512 sq.ft.	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.21% Airbnb Rental Income: $null Traditional Rental Income: $2138 Airbnb ROI: N/A Traditional ROI: 9.21%
2420 Channon Poplar Bluff, MO $129,900. 2420 Channon, Poplar Bluff, MO 63901. Remodeled, 3 bedroom house off of Barron R...	3 beds \| 1 baths \| 1,290 sq.ft.	$129,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.56% Airbnb Rental Income: $null Traditional Rental Income: $1454 Airbnb ROI: N/A Traditional ROI: 9.56%
2727 Barron Road Poplar Bluff, MO $269,900; 2727 Barron Rd Poplar Bluff, MO; Former church recently converted to residential...	3 beds \| 4 baths \| 4,308 sq.ft.	$269,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.62% Airbnb Rental Income: $null Traditional Rental Income: $2374 Airbnb ROI: N/A Traditional ROI: 7.62%
10576 Highway PP Poplar Bluff, MO Back on the market due to Buyer's financing falling through. Welcome to your charming new ...	3 beds \| 1 baths \| 1,614 sq.ft.	$110,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.7% Airbnb Rental Income: $null Traditional Rental Income: $1481 Airbnb ROI: N/A Traditional ROI: 11.7%
3603 McLane Drive Poplar Bluff, MO Step into timeless elegance with this stunning 3 bedroom, 3 bath home nestled in a desirab...	3 beds \| 3 baths \| 2,735 sq.ft.	$437,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.46% Airbnb Rental Income: $null Traditional Rental Income: $2492 Airbnb ROI: N/A Traditional ROI: 4.46%

Real Estate investment in Poplar-bluff, MO

There are 92 properties for sale in the city of Poplar Bluff . The median list price in Poplar Bluff is $188,900 and the average price per square foot is $99. In February 2026, the average monthly cash on cash return in Poplar Bluff is 8.00%. The average monthly rental income in Poplar Bluff is $1,775.

Poplar-bluff, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 92 investment properties available for sale in Poplar-bluff.

In 2026, the best neighborhood to buy investment property is Poplar Bluff.

The ROI for Short-Term is higher than the Long-Term in Poplar-bluff with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Poplar Bluff, MO

501 N 16th Street

Poplar Bluff, MO

4 beds | 4 baths | 2,520 sq.ft.

$215,000

Airbnb cash on cash: N/A

Traditional cash on cash: 11.96%

Airbnb Rental Income: $null

Traditional Rental Income: $2837

Airbnb ROI: N/A

Traditional ROI: 11.96%

108 Mayson Lane

Poplar Bluff, MO

3 beds | 2 baths | 1,527 sq.ft.

$199,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.75%

Airbnb Rental Income: $null

Traditional Rental Income: $1867

Airbnb ROI: N/A

Traditional ROI: 7.75%

2006 Holloway Drive

Poplar Bluff, MO

4 beds | 3 baths | 2,410 sq.ft.

$269,900

Airbnb cash on cash: N/A

Traditional cash on cash: 8%

Airbnb Rental Income: $null

Traditional Rental Income: $2503

Airbnb ROI: N/A

Traditional ROI: 8%

425 Davis Street

Poplar Bluff, MO

3 beds | 2 baths | 1,196 sq.ft.

$124,900

Airbnb cash on cash: N/A

Traditional cash on cash: 10.53%

Airbnb Rental Income: $null

Traditional Rental Income: $1552

Airbnb ROI: N/A

Traditional ROI: 10.53%

199 Edna Lane

Poplar Bluff, MO

5 beds | 3 baths | 2,428 sq.ft.

$299,500

Airbnb cash on cash: N/A

Traditional cash on cash: 7.1%

Airbnb Rental Income: $null

Traditional Rental Income: $2469

Airbnb ROI: N/A

Traditional ROI: 7.1%

1172 Hwy NN

Poplar Bluff, MO

4 beds | 3 baths | 2,770 sq.ft.

$378,999

Airbnb cash on cash: N/A

Traditional cash on cash: 5.75%

Airbnb Rental Income: $null

Traditional Rental Income: $2636

Airbnb ROI: N/A

Traditional ROI: 5.75%

716 Ethel Street

Poplar Bluff, MO

3 beds | 2 baths | 1,286 sq.ft.

$124,900

Airbnb cash on cash: N/A

Traditional cash on cash: 11.77%

Airbnb Rental Income: $null

Traditional Rental Income: $1676

Airbnb ROI: N/A

Traditional ROI: 11.77%

2700 Holly Trail

Poplar Bluff, MO

N/A beds | N/A baths | N/A

$330,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.73%

Airbnb Rental Income: $null

Traditional Rental Income: $1405

Airbnb ROI: N/A