Real Estate Investment Properties for Sale in Saint James, MO

Looking for investment property in Saint James, MO with high ROI ?

Explore a variety of short-term homes & houses in Saint James, MO. Invest wisely with VRBO & Saint James, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Saint James, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
20665 private drive 4361 SAINT JAMES, MO Discover 30 picturesque acres in the heart of Missouri wine country, just off Highway 68 a...	5 beds \| 3 baths \| 2,597 sq.ft.	$649,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.83% Airbnb Rental Income: $null Traditional Rental Income: $2573 Airbnb ROI: N/A Traditional ROI: 2.83%
610 Saint Michael Ave SAINT JAMES, MO Welcome home to this beautifully renovated 3-bedroom, 2-full-bath property that blends mod...	3 beds \| 2 baths \| 1,040 sq.ft.	$234,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.05% Airbnb Rental Income: $null Traditional Rental Income: $1313 Airbnb ROI: N/A Traditional ROI: 4.05%
515 W James Blvd SAINT JAMES, MO Price Improvement!!! This all-brick home offers 3 bedrooms and 2.5 bathrooms with recent u...	3 beds \| 2 baths \| 2,175 sq.ft.	$249,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.13% Airbnb Rental Income: $null Traditional Rental Income: $2174 Airbnb ROI: N/A Traditional ROI: 7.13%
16761 State Route B SAINT JAMES, MO The 1950 ranch house sits right on the state highway for easy year-round access. Itâs a ...	3 beds \| 2 baths \| 1,680 sq.ft.	$175,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.75% Airbnb Rental Income: $null Traditional Rental Income: $1950 Airbnb ROI: N/A Traditional ROI: 9.75%
29 Saint Ann Ave SAINT JAMES, MO Thereâs something special about this home the moment you pull up. The covered front porc...	3 beds \| 2 baths \| 1,532 sq.ft.	$230,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.7% Airbnb Rental Income: $null Traditional Rental Income: $1884 Airbnb ROI: N/A Traditional ROI: 6.7%
14501 County Road 2310 SAINT JAMES, MO This beautifully renovated 3-bedroom, 3.5-bath home sits on 11.52 acres (m/l) and offers p...	3 beds \| 3 baths \| 2,082 sq.ft.	$489,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.61% Airbnb Rental Income: $null Traditional Rental Income: $2758 Airbnb ROI: N/A Traditional ROI: 4.61%
402 N Louise Ave SAINT JAMES, MO Welcome to 402 N Louise Streetâan inviting 3-bedroom, 1-bath home offering comfort, valu...	3 beds \| 1 baths \| 1,096 sq.ft.	$145,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.3% Airbnb Rental Income: $null Traditional Rental Income: $1306 Airbnb ROI: N/A Traditional ROI: 7.3%

Real Estate investment in Saint-james, MO

There are 14 properties for sale in the city of Saint James . The median list price in Saint James is $452,400 and the average price per square foot is $174. In March 2026, the average monthly cash on cash return in Saint James is 5.00%. The average monthly rental income in Saint James is $2,374.

Saint-james, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 14 investment properties available for sale in Saint-james.

In 2026, the best neighborhood to buy investment property is SAINT JAMES.

The ROI for Short-Term is higher than the Long-Term in Saint-james with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Saint James, MO

20665 private drive 4361

SAINT JAMES, MO

5 beds | 3 baths | 2,597 sq.ft.

$649,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.83%

Airbnb Rental Income: $null

Traditional Rental Income: $2573

Airbnb ROI: N/A

Traditional ROI: 2.83%

610 Saint Michael Ave

SAINT JAMES, MO

3 beds | 2 baths | 1,040 sq.ft.

$234,900

Airbnb cash on cash: N/A

Traditional cash on cash: 4.05%

Airbnb Rental Income: $null

Traditional Rental Income: $1313

Airbnb ROI: N/A

Traditional ROI: 4.05%

515 W James Blvd

SAINT JAMES, MO

3 beds | 2 baths | 2,175 sq.ft.

$249,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.13%

Airbnb Rental Income: $null

Traditional Rental Income: $2174

Airbnb ROI: N/A

Traditional ROI: 7.13%

16761 State Route B

SAINT JAMES, MO

3 beds | 2 baths | 1,680 sq.ft.

$175,000

Airbnb cash on cash: N/A

Traditional cash on cash: 9.75%

Airbnb Rental Income: $null

Traditional Rental Income: $1950

Airbnb ROI: N/A

Traditional ROI: 9.75%

29 Saint Ann Ave

SAINT JAMES, MO

3 beds | 2 baths | 1,532 sq.ft.

$230,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.7%

Airbnb Rental Income: $null

Traditional Rental Income: $1884

Airbnb ROI: N/A

Traditional ROI: 6.7%

14501 County Road 2310

SAINT JAMES, MO

3 beds | 3 baths | 2,082 sq.ft.

$489,500

Airbnb cash on cash: N/A

Traditional cash on cash: 4.61%

Airbnb Rental Income: $null

Traditional Rental Income: $2758

Airbnb ROI: N/A

Traditional ROI: 4.61%

402 N Louise Ave

SAINT JAMES, MO

3 beds | 1 baths | 1,096 sq.ft.

$145,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.3%

Airbnb Rental Income: $null

Traditional Rental Income: $1306

Airbnb ROI: N/A

Traditional ROI: 7.3%

Real Estate investment in Saint-james, MO

Saint-james, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

How many investment properties are available for sale in Saint-james?

Which neighborhoods in Saint-james to invest in 2026?

Long-Term vs. Short-Term Rentals in Saint-james, Missouri: Which will earn the best returns?

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