Real Estate Investment Properties for Sale in Saint James, MO

Looking for investment property in Saint James, MO with high ROI ?

Explore a variety of short-term homes & houses in Saint James, MO. Invest wisely with VRBO & Saint James, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Saint James, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
701 Orchard St SAINT JAMES, MO 701 Orchard St, SAINT JAMES, MO 65401 \| Other	2 beds \| 1 baths \| 1,527 sq.ft.	$44,900	Airbnb cash on cash: 8.63% Traditional cash on cash: 6.44% Airbnb Rental Income: $924 Traditional Rental Income: $480 Airbnb ROI: 8.63% Traditional ROI: 6.44%
602 N Louise Ave SAINT JAMES, MO Cute 3 bedroom, 1.5 bath home with a 1 car garage with built-in storage. This ranch style...	3 beds \| 1 baths \| 1,252 sq.ft.	$169,900	Airbnb cash on cash: 2.69% Traditional cash on cash: 5% Airbnb Rental Income: $1155 Traditional Rental Income: $1148 Airbnb ROI: 2.69% Traditional ROI: 5%
484 Dunham Rd SAINT JAMES, MO Very nice 3 BD/2 BA ranch home with a full walk out basement that has an easy access to th...	3 beds \| 2 baths \| 1,932 sq.ft.	$445,900	Airbnb cash on cash: 0.35% Traditional cash on cash: 2.58% Airbnb Rental Income: $1155 Traditional Rental Income: $1705 Airbnb ROI: 0.35% Traditional ROI: 2.58%
18906 County Road 1140 SAINT JAMES, MO PRICE REDUCTION!! COUNTRY SETTING - 2.5 acres m/l with house consisting of 1332 square fee...	3 beds \| 1 baths \| 1,332 sq.ft.	$205,000	Airbnb cash on cash: 2.15% Traditional cash on cash: 5.3% Airbnb Rental Income: $1155 Traditional Rental Income: $1387 Airbnb ROI: 2.15% Traditional ROI: 5.3%
25625 State Route U SAINT JAMES, MO Adorable rustic ranch home sits on a beautiful piece of property. The long winding drivewa...	3 beds \| 2 baths \| 2,300 sq.ft.	$335,000	Airbnb cash on cash: 0.93% Traditional cash on cash: 2.6% Airbnb Rental Income: $1155 Traditional Rental Income: $1302 Airbnb ROI: 0.93% Traditional ROI: 2.6%
532 E James Blvd SAINT JAMES, MO Lovely 3 Bedroom, 2 Bath Tri-Level home. Living Room, kitchen and dining room on main leve...	4 beds \| 2 baths \| 1,618 sq.ft.	$269,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.51% Airbnb Rental Income: $null Traditional Rental Income: $1323 Airbnb ROI: N/A Traditional ROI: 3.51%
17351 County Road 1060 SAINT JAMES, MO Quiet rural setting, yet just minutes to shopping and highways. The 1.7 acre lot offers a...	3 beds \| 3 baths \| 2,346 sq.ft.	$295,000	Airbnb cash on cash: 0.94% Traditional cash on cash: 6.66% Airbnb Rental Income: $1155 Traditional Rental Income: $2363 Airbnb ROI: 0.94% Traditional ROI: 6.66%
14795 Private Drive 1122 SAINT JAMES, MO GORGEOUS 3 bed, 2 bath home with a 2 car garage situated on just nearly 3 acres! Walking i...	3 beds \| 2 baths \| 1,765 sq.ft.	$330,000	Airbnb cash on cash: 0.84% Traditional cash on cash: 2.55% Airbnb Rental Income: $1155 Traditional Rental Income: $1302 Airbnb ROI: 0.84% Traditional ROI: 2.55%
21670 County Road 3644 SAINT JAMES, MO HVAC/furnace 3 yrs old, water well 4yrs old, hardwood floors throughout and laminate in th...	3 beds \| 2 baths \| 1,392 sq.ft.	$214,000	Airbnb cash on cash: 1.99% Traditional cash on cash: 4.59% Airbnb Rental Income: $1155 Traditional Rental Income: $1302 Airbnb ROI: 1.99% Traditional ROI: 4.59%
20602 County Road 1000 SAINT JAMES, MO FIXER UPPER OPPORTUNITY - "Mom didn't like to live fancy". Big clean out, then tear out, ...	N/A beds \| N/A baths \| 1,259 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.29% Airbnb Rental Income: $null Traditional Rental Income: $771 Airbnb ROI: N/A Traditional ROI: 3.29%
19090 State Route B SAINT JAMES, MO Be prepared to fall in love with this private little hidden gem, featuring a historic home...	3 beds \| 1 baths \| 1,266 sq.ft.	$259,000	Airbnb cash on cash: 1.66% Traditional cash on cash: 3.08% Airbnb Rental Income: $1155 Traditional Rental Income: $1122 Airbnb ROI: 1.66% Traditional ROI: 3.08%
528 Christine St SAINT JAMES, MO Calling all buyers looking to put their stamp on a priced right, cute little home in St Ja...	3 beds \| 1 baths \| 1,144 sq.ft.	$185,000	Airbnb cash on cash: 2.47% Traditional cash on cash: 4.36% Airbnb Rental Income: $1155 Traditional Rental Income: $1107 Airbnb ROI: 2.47% Traditional ROI: 4.36%
1202 Primrose Ct SAINT JAMES, MO Beautifull, spacious 1800 sq ft ranch home has 3 bedrooms, 2 bathrooms and it checks all t...	3 beds \| 2 baths \| 1,802 sq.ft.	$299,900	Airbnb cash on cash: 0.84% Traditional cash on cash: 5.74% Airbnb Rental Income: $1155 Traditional Rental Income: $2157 Airbnb ROI: 0.84% Traditional ROI: 5.74%
1 Marion Dr SAINT JAMES, MO Step into this beautifully updated 3-bedroom, 2-bathroom home featuring new laminate floor...	3 beds \| 2 baths \| 1,328 sq.ft.	$165,000	Airbnb cash on cash: 2.83% Traditional cash on cash: 8.58% Airbnb Rental Income: $1155 Traditional Rental Income: $1678 Airbnb ROI: 2.83% Traditional ROI: 8.58%
34 Kathryn Dr SAINT JAMES, MO Welcome to this spacious and beautifully updated 4 bedroom, 2.5 bath home situated on 4.22...	4 beds \| 2 baths \| 2,493 sq.ft.	$309,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.34% Airbnb Rental Income: $null Traditional Rental Income: $2650 Airbnb ROI: N/A Traditional ROI: 7.34%
15460 N Highway 68 SAINT JAMES, MO Tucked away on a picturesque knoll near the Meramec River in St. James, this beautiful ran...	6 beds \| 3 baths \| 4,850 sq.ft.	$695,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.54% Airbnb Rental Income: $null Traditional Rental Income: $2569 Airbnb ROI: N/A Traditional ROI: 2.54%
515 W James Blvd SAINT JAMES, MO Welcome home to this inviting 3 bedroom, 2.5 bath property offering comfort, space, and co...	3 beds \| 2 baths \| 2,175 sq.ft.	$249,900	Airbnb cash on cash: 1.3% Traditional cash on cash: 7.23% Airbnb Rental Income: $1155 Traditional Rental Income: $2174 Airbnb ROI: 1.3% Traditional ROI: 7.23%
419 E Hardy St SAINT JAMES, MO 419 E Hardy St, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 2 baths \| 1,752 sq.ft.	$289,000	Airbnb cash on cash: 0.54% Traditional cash on cash: 3.43% Airbnb Rental Income: $1155 Traditional Rental Income: $1561 Airbnb ROI: 0.54% Traditional ROI: 3.43%
12280 County Road 3450 SAINT JAMES, MO 12280 County Road 3450, SAINT JAMES, MO 65559 \| Single Family Residential	4 beds \| 3 baths \| 2,848 sq.ft.	$345,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.01% Airbnb Rental Income: $null Traditional Rental Income: $2351 Airbnb ROI: N/A Traditional ROI: 5.01%
603 W Springfield St SAINT JAMES, MO 603 W Springfield St, SAINT JAMES, MO 65559 \| Single Family Residential	2 beds \| 1 baths \| 840 sq.ft.	$64,900	Airbnb cash on cash: 5.6% Traditional cash on cash: 9.15% Airbnb Rental Income: $924 Traditional Rental Income: $811 Airbnb ROI: 5.6% Traditional ROI: 9.15%
207 Home Ave SAINT JAMES, MO Looking for a home that's ready from day one? This fully furnished 2-bedroom, 1-bath prope...	2 beds \| 1 baths \| 806 sq.ft.	$165,000	Airbnb cash on cash: 1.7% Traditional cash on cash: 6.24% Airbnb Rental Income: $924 Traditional Rental Income: $1297 Airbnb ROI: 1.7% Traditional ROI: 6.24%
13689 County Road 3590 SAINT JAMES, MO 13689 County Road 3590, SAINT JAMES, MO 65559 \| Single Family Residential	4 beds \| 2 baths \| 1,792 sq.ft.	$289,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.47% Airbnb Rental Income: $null Traditional Rental Income: $1845 Airbnb ROI: N/A Traditional ROI: 4.47%
200 Missouri Ave SAINT JAMES, MO 200 Missouri Ave, SAINT JAMES, MO 65559 \| Single Family Residential	2 beds \| 1 baths \| 806 sq.ft.	$164,900	Airbnb cash on cash: 1.15% Traditional cash on cash: 0.5% Airbnb Rental Income: $924 Traditional Rental Income: $480 Airbnb ROI: 1.15% Traditional ROI: 0.5%
121 Anna St SAINT JAMES, MO 121 Anna St, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 1 baths \| 1,443 sq.ft.	$159,900	Airbnb cash on cash: 2.5% Traditional cash on cash: 5.3% Airbnb Rental Income: $1155 Traditional Rental Income: $1201 Airbnb ROI: 2.5% Traditional ROI: 5.3%
34 Jana Ln SAINT JAMES, MO 34 Jana Ln, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 2 baths \| 1,392 sq.ft.	$95,000	Airbnb cash on cash: 5.39% Traditional cash on cash: 11.1% Airbnb Rental Income: $1155 Traditional Rental Income: $1302 Airbnb ROI: 5.39% Traditional ROI: 11.1%
15227 County Road 1110 SAINT JAMES, MO 15227 County Road 1110, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 2 baths \| 1,888 sq.ft.	$689,900	Airbnb cash on cash: -0.91% Traditional cash on cash: -0.08% Airbnb Rental Income: $1155 Traditional Rental Income: $1302 Airbnb ROI: -0.91% Traditional ROI: -0.08%
19353 County Road 1140 SAINT JAMES, MO 19353 County Road 1140, SAINT JAMES, MO 65559 \| Other	N/A beds \| N/A baths \| N/A	$300,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.61% Airbnb Rental Income: $null Traditional Rental Income: $820 Airbnb ROI: N/A Traditional ROI: 0.61%
1524 Lola Ln SAINT JAMES, MO 1524 Lola Ln, SAINT JAMES, MO 65559 \| Single Family Residential	4 beds \| 3 baths \| 2,365 sq.ft.	$330,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.63% Airbnb Rental Income: $null Traditional Rental Income: $2139 Airbnb ROI: N/A Traditional ROI: 4.63%
20262 Highway 8 SAINT JAMES, MO 20262 Highway 8, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 1 baths \| 1,247 sq.ft.	$390,000	Airbnb cash on cash: -0.1% Traditional cash on cash: 0.87% Airbnb Rental Income: $1155 Traditional Rental Income: $1128 Airbnb ROI: -0.1% Traditional ROI: 0.87%
348 Saint Francis Ave SAINT JAMES, MO 348 Saint Francis Ave, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 1 baths \| 1,118 sq.ft.	$169,900	Airbnb cash on cash: 2.25% Traditional cash on cash: 4.47% Airbnb Rental Income: $1155 Traditional Rental Income: $1134 Airbnb ROI: 2.25% Traditional ROI: 4.47%
24701 County Road 434 SAINT JAMES, MO Discover the perfect blend of privacy, functionality, and rural charm with this unique 7.2...	3 beds \| 2 baths \| 2,784 sq.ft.	$449,500	Airbnb cash on cash: 0.18% Traditional cash on cash: 4.03% Airbnb Rental Income: $1155 Traditional Rental Income: $2394 Airbnb ROI: 0.18% Traditional ROI: 4.03%
343 Winter Dr SAINT JAMES, MO Some renovations refresh a home. This one rebuilt it. From the studs out â new drywall, ...	4 beds \| 2 baths \| 1,782 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.12% Airbnb Rental Income: $null Traditional Rental Income: $2045 Airbnb ROI: N/A Traditional ROI: 6.12%
14301 County Road 2480 SAINT JAMES, MO Ten acres of Ozark countryside, all-pavement access, and a covered deck with views that st...	3 beds \| 3 baths \| 2,220 sq.ft.	$369,800	Airbnb cash on cash: 0.77% Traditional cash on cash: 5.61% Airbnb Rental Income: $1155 Traditional Rental Income: $2453 Airbnb ROI: 0.77% Traditional ROI: 5.61%
14394 Dillon Outer Rd SAINT JAMES, MO	3 beds \| 2 baths \| 1,888 sq.ft.	$179,000	Airbnb cash on cash: 2.03% Traditional cash on cash: 5.14% Airbnb Rental Income: $1155 Traditional Rental Income: $1302 Airbnb ROI: 2.03% Traditional ROI: 5.14%
100 E Scioto St SAINT JAMES, MO 100 E Scioto St, SAINT JAMES, MO 65559 \| Single Family Residential	5 beds \| 2 baths \| 2,464 sq.ft.	$199,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.08% Airbnb Rental Income: $null Traditional Rental Income: $1990 Airbnb ROI: N/A Traditional ROI: 8.08%
433 E Scioto St SAINT JAMES, MO 433 E Scioto St, SAINT JAMES, MO 65559 \| Single Family Residential	4 beds \| 2 baths \| 1,560 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.81% Airbnb Rental Income: $null Traditional Rental Income: $1323 Airbnb ROI: N/A Traditional ROI: 3.81%
307 W Eldon St SAINT JAMES, MO 307 W Eldon St, SAINT JAMES, MO 65559 \| Single Family Residential	2 beds \| 1 baths \| 816 sq.ft.	$95,900	Airbnb cash on cash: 3.26% Traditional cash on cash: 2.18% Airbnb Rental Income: $924 Traditional Rental Income: $480 Airbnb ROI: 3.26% Traditional ROI: 2.18%
17015 County Road 1020 SAINT JAMES, MO 17015 County Road 1020, SAINT JAMES, MO 65559 \| Single Family Residential	5 beds \| 3 baths \| 4,742 sq.ft.	$649,900	Airbnb cash on cash: N/A Traditional cash on cash: 1.77% Airbnb Rental Income: $null Traditional Rental Income: $2357 Airbnb ROI: N/A Traditional ROI: 1.77%
224 W Scioto St SAINT JAMES, MO 224 W Scioto St, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 1 baths \| 1,566 sq.ft.	$229,900	Airbnb cash on cash: 1.17% Traditional cash on cash: 3.17% Airbnb Rental Income: $1155 Traditional Rental Income: $1210 Airbnb ROI: 1.17% Traditional ROI: 3.17%
19982 State Highway 8 SAINT JAMES, MO 19982 State Highway 8, SAINT JAMES, MO 65559 \| Single Family Residential	3 beds \| 2 baths \| 1,440 sq.ft.	$330,000	Airbnb cash on cash: 0.23% Traditional cash on cash: 2.28% Airbnb Rental Income: $1155 Traditional Rental Income: $1408 Airbnb ROI: 0.23% Traditional ROI: 2.28%

Real Estate investment in Saint-james, MO

There are 64 properties for sale in the city of Saint James . The median list price in Saint James is $254,450 and the average price per square foot is $148. In September 2026, the average monthly cash on cash return in Saint James is 4.00%. The average monthly rental income in Saint James is $1,302.

Saint-james, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 64 investment properties available for sale in Saint-james.

In 2026, the best neighborhood to buy investment property is SAINT JAMES.

The ROI for Long-Term is higher than the Short-Term in Saint-james with average rental income of $1,302.

Your search for investment property begins and ends here

Investment Property for Sale in Saint James, MO

701 Orchard St

SAINT JAMES, MO

2 beds | 1 baths | 1,527 sq.ft.

$44,900

Airbnb cash on cash: 8.63%

Traditional cash on cash: 6.44%

Airbnb Rental Income: $924

Traditional Rental Income: $480

Airbnb ROI: 8.63%

Traditional ROI: 6.44%

602 N Louise Ave

SAINT JAMES, MO

3 beds | 1 baths | 1,252 sq.ft.

$169,900

Airbnb cash on cash: 2.69%

Traditional cash on cash: 5%

Airbnb Rental Income: $1155

Traditional Rental Income: $1148

Airbnb ROI: 2.69%

Traditional ROI: 5%

484 Dunham Rd

SAINT JAMES, MO

3 beds | 2 baths | 1,932 sq.ft.

$445,900

Airbnb cash on cash: 0.35%

Traditional cash on cash: 2.58%

Airbnb Rental Income: $1155

Traditional Rental Income: $1705

Airbnb ROI: 0.35%

Traditional ROI: 2.58%

18906 County Road 1140

SAINT JAMES, MO

3 beds | 1 baths | 1,332 sq.ft.

$205,000

Airbnb cash on cash: 2.15%

Traditional cash on cash: 5.3%

Airbnb Rental Income: $1155

Traditional Rental Income: $1387

Airbnb ROI: 2.15%

Traditional ROI: 5.3%

25625 State Route U

SAINT JAMES, MO

3 beds | 2 baths | 2,300 sq.ft.

$335,000

Airbnb cash on cash: 0.93%

Traditional cash on cash: 2.6%

Airbnb Rental Income: $1155

Traditional Rental Income: $1302

Airbnb ROI: 0.93%

Traditional ROI: 2.6%

532 E James Blvd

SAINT JAMES, MO

4 beds | 2 baths | 1,618 sq.ft.

$269,900

Airbnb cash on cash: N/A

Traditional cash on cash: 3.51%

Airbnb Rental Income: $null

Traditional Rental Income: $1323

Airbnb ROI: N/A

Traditional ROI: 3.51%

17351 County Road 1060

SAINT JAMES, MO

3 beds | 3 baths | 2,346 sq.ft.

$295,000

Airbnb cash on cash: 0.94%

Traditional cash on cash: 6.66%

Airbnb Rental Income: $1155

Traditional Rental Income: $2363

Airbnb ROI: 0.94%

Traditional ROI: 6.66%

14795 Private Drive 1122

SAINT JAMES, MO

3 beds | 2 baths | 1,765 sq.ft.

$330,000

Airbnb cash on cash: 0.84%

Traditional cash on cash: 2.55%

Airbnb Rental Income: $1155

Traditional Rental Income: $1302

Airbnb ROI: 0.84%