Real Estate Investment Properties for Sale in Depew, NY

Looking for investment property in Depew, NY with high ROI ?

Explore a variety of short-term homes & houses in Depew, NY. Invest wisely with VRBO & Depew, NY Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Depew, NY

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
79 Terrell St Depew, NY Come check out this move-in ready home priced to sell. 2 bedrooms with a potential third i...	3 beds \| 1 baths \| 1,200 sq.ft.	$249,900	Airbnb cash on cash: 1.65% Traditional cash on cash: 2.43% Airbnb Rental Income: $1558 Traditional Rental Income: $1294 Airbnb ROI: 1.65% Traditional ROI: 2.43%
60 Park Ave Depew, NY SUPER 4 BR, 2 FULL BATH UPDATED CAPE IN MOVE-IN CONDITION*SMARTLY UPDATED AND KEPT IN IMMA...	4 beds \| 2 baths \| 1,620 sq.ft.	$309,900	Airbnb cash on cash: 1.64% Traditional cash on cash: 3.77% Airbnb Rental Income: $1876 Traditional Rental Income: $1996 Airbnb ROI: 1.64% Traditional ROI: 3.77%
26 Caroline Ln Depew, NY Priced to sell!!! Come take a look at this well maintained Depew home. Seller already b...	3 beds \| 1 baths \| 1,025 sq.ft.	$239,000	Airbnb cash on cash: 1.6% Traditional cash on cash: 3.76% Airbnb Rental Income: $1558 Traditional Rental Income: $1597 Airbnb ROI: 1.6% Traditional ROI: 3.76%
76 Doehaven Cir Depew, NY SITUATED IN DEPEW WITH LANCASTER SCHOOL DISTRICT. RAISED RANCH WITH NEW ROOF. THREE BEDROM...	3 beds \| 2 baths \| 1,606 sq.ft.	$329,900	Airbnb cash on cash: 0.49% Traditional cash on cash: 2.49% Airbnb Rental Income: $1558 Traditional Rental Income: $1728 Airbnb ROI: 0.49% Traditional ROI: 2.49%
62 Joel Dr Depew, NY 3 bedroom 1.5 bath ranch with attached 2 car garage. Depew Schools! Beautiful open floor p...	3 beds \| 1 baths \| 1,248 sq.ft.	$275,000	Airbnb cash on cash: 0.46% Traditional cash on cash: 2.27% Airbnb Rental Income: $1558 Traditional Rental Income: $1577 Airbnb ROI: 0.46% Traditional ROI: 2.27%
19 Little Pl Depew, NY Conveniently located between Walden and Broadway in Depew-Lancaster, this 1,826 SF three b...	3 beds \| 2 baths \| 1,824 sq.ft.	$189,900	Airbnb cash on cash: 2.62% Traditional cash on cash: 6.06% Airbnb Rental Income: $1558 Traditional Rental Income: $1730 Airbnb ROI: 2.62% Traditional ROI: 6.06%
40 Sebring Dr Depew, NY UPDATED 3/2 DUPLEX IN MOVE-IN CONDITIONGREAT LOCATION-RENTS EASILY*WELL MAINTAINED UNITS...	5 beds \| 2 baths \| 2,440 sq.ft.	$369,000	Airbnb cash on cash: 1.2% Traditional cash on cash: 3.13% Airbnb Rental Income: $1965 Traditional Rental Income: $2115 Airbnb ROI: 1.2% Traditional ROI: 3.13%
141 Borden Rd Depew, NY Wonderfully situated in a park like setting are 2 very well cared for and nicely updated, ...	4 beds \| 2 baths \| 2,268 sq.ft.	$290,000	Airbnb cash on cash: 1.42% Traditional cash on cash: 4.22% Airbnb Rental Income: $1965 Traditional Rental Income: $2213 Airbnb ROI: 1.42% Traditional ROI: 4.22%
114 Chateau Court Depew, NY Welcome to 114 Chateau Court! This 1,796 sq. ft. 1969 split-level offers 3 bedrooms, 2 bat...	3 beds \| 2 baths \| 1,796 sq.ft.	$250,000	Airbnb cash on cash: 0.45% Traditional cash on cash: 5.01% Airbnb Rental Income: $1558 Traditional Rental Income: $2186 Airbnb ROI: 0.45% Traditional ROI: 5.01%
12 Honorine Dr Depew, NY Fall in love with this beautifully maintained split level home on a neighborhood street, w...	3 beds \| 1 baths \| 1,501 sq.ft.	$295,000	Airbnb cash on cash: 0.69% Traditional cash on cash: 1.69% Airbnb Rental Income: $1558 Traditional Rental Income: $1389 Airbnb ROI: 0.69% Traditional ROI: 1.69%
134 Woodlawn Avenue Depew, NY Excellent opportunity for both investors and owner-occupants! Located in the highly desira...	5 beds \| 2 baths \| 2,146 sq.ft.	$289,900	Airbnb cash on cash: 1.62% Traditional cash on cash: 4.38% Airbnb Rental Income: $1965 Traditional Rental Income: $2203 Airbnb ROI: 1.62% Traditional ROI: 4.38%
5041 Broadway Depew, NY Bring your hammer and some ideas to this fixer upper in the heart of Depew! This house has...	3 beds \| 2 baths \| 1,120 sq.ft.	$179,900	Airbnb cash on cash: 3.9% Traditional cash on cash: 6.63% Airbnb Rental Income: $1558 Traditional Rental Income: $1576 Airbnb ROI: 3.9% Traditional ROI: 6.63%
272 Canton St Depew, NY Come take a look at this great investment property in a prime location. A quiet side stree...	4 beds \| 2 baths \| 1,752 sq.ft.	$199,900	Airbnb cash on cash: 2.96% Traditional cash on cash: 5.63% Airbnb Rental Income: $1876 Traditional Rental Income: $1881 Airbnb ROI: 2.96% Traditional ROI: 5.63%
41 Erie Street Depew, NY This 2 bedroom maintenance free house has an open feel from the fully applianced kitchen t...	2 beds \| 1 baths \| 798 sq.ft.	$199,900	Airbnb cash on cash: -0.31% Traditional cash on cash: 4.71% Airbnb Rental Income: $1084 Traditional Rental Income: $1667 Airbnb ROI: -0.31% Traditional ROI: 4.71%
79 Alys Drive E Depew, NY OPEN HOUSE Saturday 6/20, 12-2PM - Beautifully updated, sprawling 3-bedroom, 2 full bath r...	3 beds \| 2 baths \| 1,932 sq.ft.	$289,900	Airbnb cash on cash: 0.19% Traditional cash on cash: 3.47% Airbnb Rental Income: $1558 Traditional Rental Income: $2004 Airbnb ROI: 0.19% Traditional ROI: 3.47%
106 Olanta Street Depew, NY Welcome to 106 Olanta Street! A spacious 4 bedroom, 2 bath raised ranch home in the heart ...	4 beds \| 2 baths \| 2,592 sq.ft.	$299,900	Airbnb cash on cash: 1.04% Traditional cash on cash: 3.06% Airbnb Rental Income: $1876 Traditional Rental Income: $1946 Airbnb ROI: 1.04% Traditional ROI: 3.06%
23 Alys Drive E Depew, NY Welcome to this completely renovated 3-bedroom, 1-bath ranch offering modern updates and e...	3 beds \| 1 baths \| 1,440 sq.ft.	$199,000	Airbnb cash on cash: 2.34% Traditional cash on cash: 5.43% Airbnb Rental Income: $1558 Traditional Rental Income: $1693 Airbnb ROI: 2.34% Traditional ROI: 5.43%
25 Karen Ln Depew, NY Welcome to this fabulous home located in the Village of Depew! This beautifully updated 3-...	3 beds \| 2 baths \| 1,268 sq.ft.	$255,000	Airbnb cash on cash: 0.42% Traditional cash on cash: 4.07% Airbnb Rental Income: $1558 Traditional Rental Income: $1990 Airbnb ROI: 0.42% Traditional ROI: 4.07%
99 S Prince Drive Depew, NY WELCOME BACK TO 99 South Prince Dr! Better than ever and ready for your own personal touch...	5 beds \| 3 baths \| 2,800 sq.ft.	$389,900	Airbnb cash on cash: 0.3% Traditional cash on cash: 5.07% Airbnb Rental Income: $1965 Traditional Rental Income: $3192 Airbnb ROI: 0.3% Traditional ROI: 5.07%
1363 Losson Rd Depew, NY Nestled on almost two acres of serene landscape, this custom ranch built in 1994 has been ...	3 beds \| 1 baths \| 960 sq.ft.	$359,900	Airbnb cash on cash: 0.65% Traditional cash on cash: 2.14% Airbnb Rental Income: $1558 Traditional Rental Income: $1610 Airbnb ROI: 0.65% Traditional ROI: 2.14%
148 Parwood Trail Depew, NY Move-In Ready! Discover low-maintenance luxury living in this beautifully maintained Townh...	3 beds \| 2 baths \| 1,722 sq.ft.	$394,900	Airbnb cash on cash: -0.75% Traditional cash on cash: 2.33% Airbnb Rental Income: $1558 Traditional Rental Income: $2248 Airbnb ROI: -0.75% Traditional ROI: 2.33%
51 Laverack Ave Depew, NY *SELLER WILLING TO CONSIDER OFFERS BETWEEN $324,900 and $374,900* Welcome to 51 Lavera...	5 beds \| 3 baths \| 2,039 sq.ft.	$324,899	Airbnb cash on cash: 1.13% Traditional cash on cash: 7.55% Airbnb Rental Income: $1558 Traditional Rental Income: $3072 Airbnb ROI: 1.13% Traditional ROI: 7.55%
140 Cloverleaf Ct #1 Depew, NY 140 Cloverleaf Ct #1, Depew, NY 14043 \| Townhouse	2 beds \| 2 baths \| 1,621 sq.ft.	$432,900	Airbnb cash on cash: -2.21% Traditional cash on cash: 0.71% Airbnb Rental Income: $1084 Traditional Rental Income: $1897 Airbnb ROI: -2.21% Traditional ROI: 0.71%
150 Cloverleaf Ct #1 Depew, NY 150 Cloverleaf Ct #1, Depew, NY 14043 \| Townhouse	2 beds \| 2 baths \| 1,621 sq.ft.	$432,900	Airbnb cash on cash: -2.21% Traditional cash on cash: 0.71% Airbnb Rental Income: $1084 Traditional Rental Income: $1897 Airbnb ROI: -2.21% Traditional ROI: 0.71%
182 Messer Ave Depew, NY 182 Messer Ave, Depew, NY 14043 \| Single Family Residential	3 beds \| 2 baths \| 2,195 sq.ft.	$449,900	Airbnb cash on cash: -0.29% Traditional cash on cash: 1.79% Airbnb Rental Income: $1558 Traditional Rental Income: $1986 Airbnb ROI: -0.29% Traditional ROI: 1.79%
4 Wendel St Depew, NY 4 Wendel St, Depew, NY 14043 \| Single Family Residential	3 beds \| 1 baths \| 1,137 sq.ft.	$198,000	Airbnb cash on cash: 2.72% Traditional cash on cash: 3.41% Airbnb Rental Income: $1558 Traditional Rental Income: $1240 Airbnb ROI: 2.72% Traditional ROI: 3.41%
1 Wendel St Depew, NY 1 Wendel St, Depew, NY 14043 \| Multi Family	6 beds \| 2 baths \| 2,080 sq.ft.	$285,000	Airbnb cash on cash: 1.08% Traditional cash on cash: 4.21% Airbnb Rental Income: $1558 Traditional Rental Income: $1948 Airbnb ROI: 1.08% Traditional ROI: 4.21%
7 Cloyes Ave Depew, NY 7 Cloyes Ave, Depew, NY 14043 \| Multi Family	2 beds \| 2 baths \| 1,588 sq.ft.	$210,000	Airbnb cash on cash: 2.41% Traditional cash on cash: 4.05% Airbnb Rental Income: $1558 Traditional Rental Income: $1436 Airbnb ROI: 2.41% Traditional ROI: 4.05%
4670 Broadway Depew, NY 4670 Broadway, Depew, NY 14043 \| Single Family Residential	4 beds \| 1 baths \| 1,671 sq.ft.	$144,900	Airbnb cash on cash: 6.55% Traditional cash on cash: 5.2% Airbnb Rental Income: $1876 Traditional Rental Income: $1187 Airbnb ROI: 6.55% Traditional ROI: 5.2%
5831 Transit Rd Depew, NY 5831 Transit Rd, Depew, NY 14043 \| Single Family Residential	2 beds \| N/A baths \| 3,158 sq.ft.	$349,000	Airbnb cash on cash: -0.8% Traditional cash on cash: 0.63% Airbnb Rental Income: $1084 Traditional Rental Income: $1186 Airbnb ROI: -0.8% Traditional ROI: 0.63%
160 Cloverleaf Ct #2 Depew, NY 160 Cloverleaf Ct #2, Depew, NY 14043 \| Townhouse	3 beds \| 2 baths \| 1,449 sq.ft.	$407,900	Airbnb cash on cash: -1.15% Traditional cash on cash: 0.64% Airbnb Rental Income: $1558 Traditional Rental Income: $1793 Airbnb ROI: -1.15% Traditional ROI: 0.64%
465 Rowley Rd Depew, NY Well-kept 3-bedroom, 2.5-bath Colonial in the desirable Marywood Farms neighborhood, offer...	3 beds \| 2 baths \| 1,651 sq.ft.	$351,000	Airbnb cash on cash: 0.26% Traditional cash on cash: 4.27% Airbnb Rental Income: $1558 Traditional Rental Income: $2430 Airbnb ROI: 0.26% Traditional ROI: 4.27%
500 Rowley Road Depew, NY Welcome to this spacious and versatile 5 bedroom home in the heart of Depew! This property...	5 beds \| 2 baths \| 1,937 sq.ft.	$324,900	Airbnb cash on cash: 1.52% Traditional cash on cash: 5.05% Airbnb Rental Income: $1965 Traditional Rental Income: $2527 Airbnb ROI: 1.52% Traditional ROI: 5.05%
31 Albert Street Depew, NY Welcome to 31 Albert Street - a spacious ranch with room to grow, located in the highly so...	3 beds \| 2 baths \| 1,150 sq.ft.	$174,900	Airbnb cash on cash: 0.89% Traditional cash on cash: 6.02% Airbnb Rental Income: $1558 Traditional Rental Income: $1964 Airbnb ROI: 0.89% Traditional ROI: 6.02%

Real Estate investment in Depew, NY

There are 117 properties for sale in the city of Depew . The median list price in Depew is $277,834 and the average price per square foot is $173. In August 2026, the average monthly cash on cash return in Depew is 3.00%. The average monthly rental income in Depew is $1,776.

Depew, NY Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 117 investment properties available for sale in Depew.

In 2026, the best neighborhood to buy investment property is Depew.

The ROI for Long-Term is higher than the Short-Term in Depew with average rental income of $1,776.

Your search for investment property begins and ends here

Investment Property for Sale in Depew, NY

79 Terrell St

Depew, NY

3 beds | 1 baths | 1,200 sq.ft.

$249,900

Airbnb cash on cash: 1.65%

Traditional cash on cash: 2.43%

Airbnb Rental Income: $1558

Traditional Rental Income: $1294

Airbnb ROI: 1.65%

Traditional ROI: 2.43%

60 Park Ave

Depew, NY

4 beds | 2 baths | 1,620 sq.ft.

$309,900

Airbnb cash on cash: 1.64%

Traditional cash on cash: 3.77%

Airbnb Rental Income: $1876

Traditional Rental Income: $1996

Airbnb ROI: 1.64%

Traditional ROI: 3.77%

26 Caroline Ln

Depew, NY

3 beds | 1 baths | 1,025 sq.ft.

$239,000

Airbnb cash on cash: 1.6%

Traditional cash on cash: 3.76%

Airbnb Rental Income: $1558

Traditional Rental Income: $1597

Airbnb ROI: 1.6%

Traditional ROI: 3.76%

76 Doehaven Cir

Depew, NY

3 beds | 2 baths | 1,606 sq.ft.

$329,900

Airbnb cash on cash: 0.49%

Traditional cash on cash: 2.49%

Airbnb Rental Income: $1558

Traditional Rental Income: $1728

Airbnb ROI: 0.49%

Traditional ROI: 2.49%

62 Joel Dr

Depew, NY

3 beds | 1 baths | 1,248 sq.ft.

$275,000

Airbnb cash on cash: 0.46%

Traditional cash on cash: 2.27%

Airbnb Rental Income: $1558

Traditional Rental Income: $1577

Airbnb ROI: 0.46%

Traditional ROI: 2.27%

19 Little Pl

Depew, NY

3 beds | 2 baths | 1,824 sq.ft.

$189,900

Airbnb cash on cash: 2.62%

Traditional cash on cash: 6.06%

Airbnb Rental Income: $1558

Traditional Rental Income: $1730

Airbnb ROI: 2.62%

Traditional ROI: 6.06%

40 Sebring Dr

Depew, NY

5 beds | 2 baths | 2,440 sq.ft.

$369,000

Airbnb cash on cash: 1.2%

Traditional cash on cash: 3.13%

Airbnb Rental Income: $1965

Traditional Rental Income: $2115

Airbnb ROI: 1.2%

Traditional ROI: 3.13%

141 Borden Rd

Depew, NY

4 beds | 2 baths | 2,268 sq.ft.

$290,000

Airbnb cash on cash: 1.42%

Traditional cash on cash: 4.22%

Airbnb Rental Income: $1965

Traditional Rental Income: $2213

Airbnb ROI: 1.42%