Real Estate Investment Properties for Sale in Defiance, OH

Looking for investment property in Defiance, OH with high ROI ?

Explore a variety of short-term homes & houses in Defiance, OH. Invest wisely with VRBO & Defiance, OH Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Defiance, OH

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2851 N State Route 66 Defiance, OH Buy through Auction.com. This property is being offered for sale exclusively on Auction.co...	3 beds \| 2 baths \| 2,226 sq.ft.	$319,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.66% Airbnb Rental Income: $null Traditional Rental Income: $2219 Airbnb ROI: N/A Traditional ROI: 5.66%
823 Nicholas St Defiance, OH 823 Nicholas St, Defiance, OH 43512 \| Single Family Residential	2 beds \| 1 baths \| 912 sq.ft.	$122,000	Airbnb cash on cash: -0.12% Traditional cash on cash: 6.45% Airbnb Rental Income: $693 Traditional Rental Income: $1198 Airbnb ROI: -0.12% Traditional ROI: 6.45%
214 Union St Defiance, OH 214 Union St, Defiance, OH 43512 \| Single Family Residential	2 beds \| 1 baths \| 1,100 sq.ft.	$164,900	Airbnb cash on cash: -0.65% Traditional cash on cash: 6.4% Airbnb Rental Income: $693 Traditional Rental Income: $1497 Airbnb ROI: -0.65% Traditional ROI: 6.4%
218 Union St Defiance, OH 218 Union St, Defiance, OH 43512 \| Single Family Residential	2 beds \| 1 baths \| 1,100 sq.ft.	$164,900	Airbnb cash on cash: -0.65% Traditional cash on cash: 6.67% Airbnb Rental Income: $693 Traditional Rental Income: $1540 Airbnb ROI: -0.65% Traditional ROI: 6.67%
16407 St Rt 15 Defiance, OH 16407 St Rt 15, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 2,125 sq.ft.	$299,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.5% Airbnb Rental Income: $null Traditional Rental Income: $2363 Airbnb ROI: N/A Traditional ROI: 5.5%
13332 St Rt 15 Defiance, OH 13332 St Rt 15, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 1,741 sq.ft.	$359,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.45% Airbnb Rental Income: $null Traditional Rental Income: $2113 Airbnb ROI: N/A Traditional ROI: 3.45%
1481 Lee Ann Ave Defiance, OH 1481 Lee Ann Ave, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 2,072 sq.ft.	$319,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.98% Airbnb Rental Income: $null Traditional Rental Income: $2688 Airbnb ROI: N/A Traditional ROI: 5.98%
85 Cypress Hill Dr Defiance, OH 85 Cypress Hill Dr, Defiance, OH 43512 \| Townhouse	3 beds \| 2 baths \| 1,433 sq.ft.	$230,300	Airbnb cash on cash: N/A Traditional cash on cash: 7.53% Airbnb Rental Income: $null Traditional Rental Income: $2283 Airbnb ROI: N/A Traditional ROI: 7.53%
1506 Bristow Ct Defiance, OH 1506 Bristow Ct, Defiance, OH 43512 \| Condo/Coop	2 beds \| 2 baths \| 1,674 sq.ft.	$315,000	Airbnb cash on cash: -2.33% Traditional cash on cash: -0.09% Airbnb Rental Income: $693 Traditional Rental Income: $1053 Airbnb ROI: -2.33% Traditional ROI: -0.09%
905 Corwin St Defiance, OH 905 Corwin St, Defiance, OH 43512 \| Single Family Residential	4 beds \| 3 baths \| 2,720 sq.ft.	$314,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.76% Airbnb Rental Income: $null Traditional Rental Income: $3194 Airbnb ROI: N/A Traditional ROI: 7.76%
1017 Wayne Ave Defiance, OH 1017 Wayne Ave, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 1,248 sq.ft.	$160,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.23% Airbnb Rental Income: $null Traditional Rental Income: $1737 Airbnb ROI: N/A Traditional ROI: 8.23%
1398 Milwaukee Ave Defiance, OH	1 beds \| 1 baths \| 520 sq.ft.	$53,000	Airbnb cash on cash: -4.94% Traditional cash on cash: 11.16% Airbnb Rental Income: $180 Traditional Rental Income: $826 Airbnb ROI: -4.94% Traditional ROI: 11.16%
1765 S Jefferson Ave Defiance, OH 1765 S Jefferson Ave, Defiance, OH 43512 \| Other	N/A beds \| N/A baths \| N/A	$95,000	Airbnb cash on cash: 7.96% Traditional cash on cash: 6.06% Airbnb Rental Income: $1503 Traditional Rental Income: $888 Airbnb ROI: 7.96% Traditional ROI: 6.06%
207 Jefferson Ave Defiance, OH 207 Jefferson Ave, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 2,294 sq.ft.	$250,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.15% Airbnb Rental Income: $null Traditional Rental Income: $2381 Airbnb ROI: N/A Traditional ROI: 7.15%
8820 Ohio 15 Defiance, OH 8820 Ohio 15, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,568 sq.ft.	$186,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.37% Airbnb Rental Income: $null Traditional Rental Income: $1667 Airbnb ROI: N/A Traditional ROI: 6.37%
Chatham Plan Defiance, OH Chatham Plan, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 1,771 sq.ft.	$274,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.75% Airbnb Rental Income: $null Traditional Rental Income: $2242 Airbnb ROI: N/A Traditional ROI: 5.75%
Henley Plan Defiance, OH Henley Plan, Defiance, OH 43512 \| Single Family Residential	5 beds \| 3 baths \| 2,600 sq.ft.	$306,900	Airbnb cash on cash: -0.54% Traditional cash on cash: 7.24% Airbnb Rental Income: $1033 Traditional Rental Income: $2917 Airbnb ROI: -0.54% Traditional ROI: 7.24%
Pine Plan Defiance, OH Pine Plan, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 1,953 sq.ft.	$276,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.91% Airbnb Rental Income: $null Traditional Rental Income: $2298 Airbnb ROI: N/A Traditional ROI: 5.91%
Bellamy Plan Defiance, OH Bellamy Plan, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 2,053 sq.ft.	$283,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.85% Airbnb Rental Income: $null Traditional Rental Income: $2337 Airbnb ROI: N/A Traditional ROI: 5.85%
Elm Plan Defiance, OH Elm Plan, Defiance, OH 43512 \| Single Family Residential	5 beds \| 3 baths \| 2,415 sq.ft.	$296,900	Airbnb cash on cash: -0.47% Traditional cash on cash: 7.26% Airbnb Rental Income: $1033 Traditional Rental Income: $2832 Airbnb ROI: -0.47% Traditional ROI: 7.26%
Elder Plan Defiance, OH Elder Plan, Defiance, OH 43512 \| Single Family Residential	4 beds \| 2 baths \| 2,156 sq.ft.	$286,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.9% Airbnb Rental Income: $null Traditional Rental Income: $2374 Airbnb ROI: N/A Traditional ROI: 5.9%
Cabral Plan Defiance, OH Cabral Plan, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 1,657 sq.ft.	$266,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.48% Airbnb Rental Income: $null Traditional Rental Income: $2112 Airbnb ROI: N/A Traditional ROI: 5.48%
508 Ralston Ave Defiance, OH 508 Ralston Ave, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,582 sq.ft.	$199,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.79% Airbnb Rental Income: $null Traditional Rental Income: $1665 Airbnb ROI: N/A Traditional ROI: 5.79%
1929 Whispering Pines Dr Defiance, OH 1929 Whispering Pines Dr, Defiance, OH 43512 \| Townhouse	4 beds \| 2 baths \| 1,811 sq.ft.	$257,864	Airbnb cash on cash: N/A Traditional cash on cash: 7.98% Airbnb Rental Income: $null Traditional Rental Income: $2649 Airbnb ROI: N/A Traditional ROI: 7.98%
304 Hopkins St Defiance, OH 304 Hopkins St, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,062 sq.ft.	$105,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.22% Airbnb Rental Income: $null Traditional Rental Income: $1493 Airbnb ROI: N/A Traditional ROI: 11.22%
580 3 Rivers Ct Defiance, OH 580 3 Rivers Ct, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 1,760 sq.ft.	$292,500	Airbnb cash on cash: N/A Traditional cash on cash: 5.28% Airbnb Rental Income: $null Traditional Rental Income: $2155 Airbnb ROI: N/A Traditional ROI: 5.28%
614 Danforth St Defiance, OH 614 Danforth St, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 2,016 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.81% Airbnb Rental Income: $null Traditional Rental Income: $2258 Airbnb ROI: N/A Traditional ROI: 5.81%
28643 Standley Rd Defiance, OH 28643 Standley Rd, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,822 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.14% Airbnb Rental Income: $null Traditional Rental Income: $1624 Airbnb ROI: N/A Traditional ROI: 8.14%
1017 Washington Ave Defiance, OH 1017 Washington Ave, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,140 sq.ft.	$160,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.82% Airbnb Rental Income: $null Traditional Rental Income: $1521 Airbnb ROI: N/A Traditional ROI: 6.82%
24603 Watson Rd Defiance, OH 24603 Watson Rd, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,088 sq.ft.	$170,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.23% Airbnb Rental Income: $null Traditional Rental Income: $1512 Airbnb ROI: N/A Traditional ROI: 6.23%
827 Washington Ave Defiance, OH 827 Washington Ave, Defiance, OH 43512 \| Single Family Residential	3 beds \| 1 baths \| 1,224 sq.ft.	$179,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.02% Airbnb Rental Income: $null Traditional Rental Income: $1558 Airbnb ROI: N/A Traditional ROI: 6.02%
1220 Jackson Ave Defiance, OH 1220 Jackson Ave, Defiance, OH 43512 \| Single Family Residential	4 beds \| 1 baths \| 1,341 sq.ft.	$169,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.51% Airbnb Rental Income: $null Traditional Rental Income: $1720 Airbnb ROI: N/A Traditional ROI: 7.51%
19879 Switzer Rd Defiance, OH 19879 Switzer Rd, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 1,520 sq.ft.	$390,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.88% Airbnb Rental Income: $null Traditional Rental Income: $2078 Airbnb ROI: N/A Traditional ROI: 2.88%
1776 Arrowhead Ct Defiance, OH 1776 Arrowhead Ct, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 2,306 sq.ft.	$395,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.81% Airbnb Rental Income: $null Traditional Rental Income: $1337 Airbnb ROI: N/A Traditional ROI: 0.81%
705 Thurston St Defiance, OH	4 beds \| 1 baths \| 1,455 sq.ft.	$132,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.18% Airbnb Rental Income: $null Traditional Rental Income: $1716 Airbnb ROI: N/A Traditional ROI: 10.18%
Harmony Plan Defiance, OH Harmony Plan, Defiance, OH 43512 \| Single Family Residential	3 beds \| 2 baths \| 1,498 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.49% Airbnb Rental Income: $null Traditional Rental Income: $2063 Airbnb ROI: N/A Traditional ROI: 5.49%

Real Estate investment in Defiance, OH

There are 57 properties for sale in the city of Defiance . The median list price in Defiance is $244,900 and the average price per square foot is $145. In May 2026, the average monthly cash on cash return in Defiance is 6.00%. The average monthly rental income in Defiance is $2,113.

Defiance, OH Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 57 investment properties available for sale in Defiance.

In 2026, the best neighborhood to buy investment property is Defiance.

The ROI for Long-Term is higher than the Short-Term in Defiance with average rental income of $2,113.

Your search for investment property begins and ends here

Investment Property for Sale in Defiance, OH

2851 N State Route 66

Defiance, OH

3 beds | 2 baths | 2,226 sq.ft.

$319,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.66%

Airbnb Rental Income: $null

Traditional Rental Income: $2219

Airbnb ROI: N/A

Traditional ROI: 5.66%

823 Nicholas St

Defiance, OH

2 beds | 1 baths | 912 sq.ft.

$122,000

Airbnb cash on cash: -0.12%

Traditional cash on cash: 6.45%

Airbnb Rental Income: $693

Traditional Rental Income: $1198

Airbnb ROI: -0.12%

Traditional ROI: 6.45%

214 Union St

Defiance, OH

2 beds | 1 baths | 1,100 sq.ft.

$164,900

Airbnb cash on cash: -0.65%

Traditional cash on cash: 6.4%

Airbnb Rental Income: $693

Traditional Rental Income: $1497

Airbnb ROI: -0.65%

Traditional ROI: 6.4%

218 Union St

Defiance, OH

2 beds | 1 baths | 1,100 sq.ft.

$164,900

Airbnb cash on cash: -0.65%

Traditional cash on cash: 6.67%

Airbnb Rental Income: $693

Traditional Rental Income: $1540

Airbnb ROI: -0.65%

Traditional ROI: 6.67%

16407 St Rt 15

Defiance, OH

4 beds | 2 baths | 2,125 sq.ft.

$299,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.5%

Airbnb Rental Income: $null

Traditional Rental Income: $2363

Airbnb ROI: N/A

Traditional ROI: 5.5%

13332 St Rt 15

Defiance, OH

3 beds | 2 baths | 1,741 sq.ft.

$359,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.45%

Airbnb Rental Income: $null

Traditional Rental Income: $2113

Airbnb ROI: N/A

Traditional ROI: 3.45%

1481 Lee Ann Ave

Defiance, OH

4 beds | 2 baths | 2,072 sq.ft.

$319,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.98%

Airbnb Rental Income: $null

Traditional Rental Income: $2688

Airbnb ROI: N/A

Traditional ROI: 5.98%

85 Cypress Hill Dr

Defiance, OH

3 beds | 2 baths | 1,433 sq.ft.

$230,300

Airbnb cash on cash: N/A

Traditional cash on cash: 7.53%

Airbnb Rental Income: $null

Traditional Rental Income: $2283

Airbnb ROI: N/A