Real Estate Investment Properties for Sale in Seneca, PA

Looking for investment property in Seneca, PA with high ROI ?

Explore a variety of short-term homes & houses in Seneca, PA. Invest wisely with VRBO & Seneca, PA Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, PA

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
7201 Us Rt. 322 Seneca, PA This amazing house is a must see! It features 4 large bedrooms, laundry located on the upp...	4 beds \| 1 baths \| N/A	$290,000	Airbnb cash on cash: 1.26% Traditional cash on cash: 6.72% Airbnb Rental Income: $1324 Traditional Rental Income: $2406 Airbnb ROI: 1.26% Traditional ROI: 6.72%
6608 US 322 Seneca, PA Are you looking for a unique opportunity to own a spacious home on 5.47 acres in Cranberry...	3 beds \| 1 baths \| 2,688 sq.ft.	$190,000	Airbnb cash on cash: 0.88% Traditional cash on cash: 8.66% Airbnb Rental Income: $1121 Traditional Rental Income: $2149 Airbnb ROI: 0.88% Traditional ROI: 8.66%
2372 Cranberry Rockland Rd Seneca, PA 2372 Cranberry Rockland Rd, Seneca, PA 16319 \| Other	N/A beds \| N/A baths \| N/A	$469,000	Airbnb cash on cash: N/A Traditional cash on cash: -1.01% Airbnb Rental Income: $null Traditional Rental Income: $775 Airbnb ROI: N/A Traditional ROI: -1.01%
161 Autumn Haze Lane Seneca, PA Don't let the one bedroom listing fool you! The perfect blend of privacy and functionality...	1 beds \| 1 baths \| 1,120 sq.ft.	$300,000	Airbnb cash on cash: -0.27% Traditional cash on cash: 4.54% Airbnb Rental Income: $853 Traditional Rental Income: $1879 Airbnb ROI: -0.27% Traditional ROI: 4.54%
0 State Route 257 Seneca, PA 0 State Route 257, Seneca, PA 16346 \| Other	N/A beds \| N/A baths \| N/A	$70,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.51% Airbnb Rental Income: $null Traditional Rental Income: $720 Airbnb ROI: N/A Traditional ROI: 6.51%
191 East State Rd Seneca, PA 191 East State Rd, Seneca, PA 16346 \| Single Family Residential	3 beds \| 1 baths \| 1,252 sq.ft.	$189,000	Airbnb cash on cash: 1.08% Traditional cash on cash: 5.85% Airbnb Rental Income: $1121 Traditional Rental Income: $1602 Airbnb ROI: 1.08% Traditional ROI: 5.85%
176 N Main St Seneca, PA 176 N Main St, Seneca, PA 16346 \| Single Family Residential	4 beds \| 1 baths \| 1,970 sq.ft.	$184,900	Airbnb cash on cash: 2.12% Traditional cash on cash: 6.28% Airbnb Rental Income: $1324 Traditional Rental Income: $1645 Airbnb ROI: 2.12% Traditional ROI: 6.28%
00 Osender Rd Seneca, PA 00 Osender Rd, Seneca, PA 16346 \| Other	N/A beds \| N/A baths \| N/A	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.21% Airbnb Rental Income: $null Traditional Rental Income: $775 Airbnb ROI: N/A Traditional ROI: 2.21%

Real Estate investment in Seneca, PA

There are 8 properties for sale in the city of Seneca . The median list price in Seneca is $380,000 and the average price per square foot is $221. In January 2026, the average monthly cash on cash return in Seneca is 6.00%. The average monthly rental income in Seneca is $1,602.

Seneca, PA Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 8 investment properties available for sale in Seneca.

In 2026, the best neighborhood to buy investment property is Seneca.

The ROI for Long-Term is higher than the Short-Term in Seneca with average rental income of $1,602.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, PA

7201 Us Rt. 322

Seneca, PA

4 beds | 1 baths | N/A

$290,000

Airbnb cash on cash: 1.26%

Traditional cash on cash: 6.72%

Airbnb Rental Income: $1324

Traditional Rental Income: $2406

Airbnb ROI: 1.26%

Traditional ROI: 6.72%

6608 US 322

Seneca, PA

3 beds | 1 baths | 2,688 sq.ft.

$190,000

Airbnb cash on cash: 0.88%

Traditional cash on cash: 8.66%

Airbnb Rental Income: $1121

Traditional Rental Income: $2149

Airbnb ROI: 0.88%

Traditional ROI: 8.66%

2372 Cranberry Rockland Rd

Seneca, PA

N/A beds | N/A baths | N/A

$469,000

Airbnb cash on cash: N/A

Traditional cash on cash: -1.01%

Airbnb Rental Income: $null

Traditional Rental Income: $775

Airbnb ROI: N/A

Traditional ROI: -1.01%

161 Autumn Haze Lane

Seneca, PA

1 beds | 1 baths | 1,120 sq.ft.

$300,000

Airbnb cash on cash: -0.27%

Traditional cash on cash: 4.54%

Airbnb Rental Income: $853

Traditional Rental Income: $1879

Airbnb ROI: -0.27%

Traditional ROI: 4.54%

0 State Route 257

Seneca, PA

N/A beds | N/A baths | N/A

$70,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.51%

Airbnb Rental Income: $null

Traditional Rental Income: $720

Airbnb ROI: N/A

Traditional ROI: 6.51%

191 East State Rd

Seneca, PA

3 beds | 1 baths | 1,252 sq.ft.

$189,000

Airbnb cash on cash: 1.08%

Traditional cash on cash: 5.85%

Airbnb Rental Income: $1121

Traditional Rental Income: $1602

Airbnb ROI: 1.08%

Traditional ROI: 5.85%

176 N Main St

Seneca, PA

4 beds | 1 baths | 1,970 sq.ft.

$184,900

Airbnb cash on cash: 2.12%

Traditional cash on cash: 6.28%

Airbnb Rental Income: $1324

Traditional Rental Income: $1645

Airbnb ROI: 2.12%

Traditional ROI: 6.28%

00 Osender Rd

Seneca, PA

N/A beds | N/A baths | N/A

$149,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.21%

Airbnb Rental Income: $null

Traditional Rental Income: $775

Airbnb ROI: N/A