Real Estate Investment Properties for Sale in Seneca, PA

Looking for investment property in Seneca, PA with high ROI ?

Explore a variety of short-term homes & houses in Seneca, PA. Invest wisely with VRBO & Seneca, PA Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, PA

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2372 Cranberry Rockland Rd Seneca, PA 2372 Cranberry Rockland Rd, Seneca, PA 16319 \| Other	N/A beds \| N/A baths \| N/A	$469,000	Airbnb cash on cash: N/A Traditional cash on cash: -1.01% Airbnb Rental Income: $null Traditional Rental Income: $775 Airbnb ROI: N/A Traditional ROI: -1.01%
1097 Tarklin Rd Seneca, PA Embrace the country lifestyle on this beautiful 19.69-acre mini-farm in the Fertigs area. ...	4 beds \| 3 baths \| 2,616 sq.ft.	$525,000	Airbnb cash on cash: -0.38% Traditional cash on cash: 4.84% Airbnb Rental Income: $1148 Traditional Rental Income: $3330 Airbnb ROI: -0.38% Traditional ROI: 4.84%
245 Harvey Dr Seneca, PA Don't miss out on this nicely landscaped family home located in the desirable Cranberry Sc...	3 beds \| N/A baths \| 1,374 sq.ft.	$218,000	Airbnb cash on cash: 1.53% Traditional cash on cash: 7.91% Airbnb Rental Income: $1161 Traditional Rental Income: $2097 Airbnb ROI: 1.53% Traditional ROI: 7.91%
0 State Rte 257 Seneca, PA 0 State Route 257, Seneca, PA 16346 \| Other	N/A beds \| N/A baths \| N/A	$95,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.85% Airbnb Rental Income: $null Traditional Rental Income: $777 Airbnb ROI: N/A Traditional ROI: 4.85%
00 Osender Rd Seneca, PA 00 Osender Rd, Seneca, PA 16346 \| Other	N/A beds \| N/A baths \| N/A	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.21% Airbnb Rental Income: $null Traditional Rental Income: $775 Airbnb ROI: N/A Traditional ROI: 2.21%
527 Heckathorn Church Rd Seneca, PA 527 Heckathorn Church Rd, Seneca, PA 16346 \| Single Family Residential	3 beds \| N/A baths \| 1,308 sq.ft.	$149,000	Airbnb cash on cash: 2.26% Traditional cash on cash: 9.74% Airbnb Rental Income: $1161 Traditional Rental Income: $1845 Airbnb ROI: 2.26% Traditional ROI: 9.74%
539 Heckathorn Church Rd Seneca, PA This beautifully updated home on 2.53 acres offers abundant natural light throughout! You'...	4 beds \| 2 baths \| 2,580 sq.ft.	$349,900	Airbnb cash on cash: 0.31% Traditional cash on cash: 6.68% Airbnb Rental Income: $1148 Traditional Rental Income: $2861 Airbnb ROI: 0.31% Traditional ROI: 6.68%
122 S Main St Seneca, PA 122 S Main St, Seneca, PA 16346 \| Single Family Residential	1 beds \| N/A baths \| 2,700 sq.ft.	$139,900	Airbnb cash on cash: -2.24% Traditional cash on cash: 7.14% Airbnb Rental Income: $387 Traditional Rental Income: $1393 Airbnb ROI: -2.24% Traditional ROI: 7.14%
164 Fairfield Ave Seneca, PA 164 Fairfield Ave, Seneca, PA 16346 \| Single Family Residential	4 beds \| 1 baths \| 1,541 sq.ft.	$269,900	Airbnb cash on cash: 0.09% Traditional cash on cash: 4.37% Airbnb Rental Income: $1148 Traditional Rental Income: $1856 Airbnb ROI: 0.09% Traditional ROI: 4.37%
226 Brumbaugh Ln Seneca, PA 226 Brumbaugh Ln, Seneca, PA 16346 \| Other	N/A beds \| N/A baths \| N/A	$69,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.19% Airbnb Rental Income: $null Traditional Rental Income: $905 Airbnb ROI: N/A Traditional ROI: 9.19%
0 Horsecreek Rd Seneca, PA 0 Horsecreek Rd, Seneca, PA 16346 \| Other	N/A beds \| N/A baths \| N/A	$63,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.35% Airbnb Rental Income: $null Traditional Rental Income: $720 Airbnb ROI: N/A Traditional ROI: 3.35%
3588 State Rt. 257 Seneca, PA 3588 State Rt. 257, Seneca, PA 16346 \| Single Family Residential	3 beds \| 1 baths \| 1,500 sq.ft.	$185,000	Airbnb cash on cash: 1.34% Traditional cash on cash: 6.45% Airbnb Rental Income: $1161 Traditional Rental Income: $1678 Airbnb ROI: 1.34% Traditional ROI: 6.45%
250 HARVEY Drive Seneca, PA THREE BEDROOM, TWO FULL BATHROOM HOME WITH FENCED YARD AND SPACIOUS COVERED DECK. HARDWOOD...	3 beds \| 2 baths \| 2,200 sq.ft.	$315,000	Airbnb cash on cash: 0.66% Traditional cash on cash: 6.52% Airbnb Rental Income: $1161 Traditional Rental Income: $2516 Airbnb ROI: 0.66% Traditional ROI: 6.52%

Real Estate investment in Seneca, PA

There are 14 properties for sale in the city of Seneca . The median list price in Seneca is $174,895 and the average price per square foot is $94. In August 2026, the average monthly cash on cash return in Seneca is 7.00%. The average monthly rental income in Seneca is $1,536.

Seneca, PA Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 14 investment properties available for sale in Seneca.

In 2026, the best neighborhood to buy investment property is Seneca.

The ROI for Long-Term is higher than the Short-Term in Seneca with average rental income of $1,536.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, PA

2372 Cranberry Rockland Rd

Seneca, PA

N/A beds | N/A baths | N/A

$469,000

Airbnb cash on cash: N/A

Traditional cash on cash: -1.01%

Airbnb Rental Income: $null

Traditional Rental Income: $775

Airbnb ROI: N/A

Traditional ROI: -1.01%

1097 Tarklin Rd

Seneca, PA

4 beds | 3 baths | 2,616 sq.ft.

$525,000

Airbnb cash on cash: -0.38%

Traditional cash on cash: 4.84%

Airbnb Rental Income: $1148

Traditional Rental Income: $3330

Airbnb ROI: -0.38%

Traditional ROI: 4.84%

245 Harvey Dr

Seneca, PA

3 beds | N/A baths | 1,374 sq.ft.

$218,000

Airbnb cash on cash: 1.53%

Traditional cash on cash: 7.91%

Airbnb Rental Income: $1161

Traditional Rental Income: $2097

Airbnb ROI: 1.53%

Traditional ROI: 7.91%

0 State Rte 257

Seneca, PA

N/A beds | N/A baths | N/A

$95,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.85%

Airbnb Rental Income: $null

Traditional Rental Income: $777

Airbnb ROI: N/A

Traditional ROI: 4.85%

00 Osender Rd

Seneca, PA

N/A beds | N/A baths | N/A

$149,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.21%

Airbnb Rental Income: $null

Traditional Rental Income: $775

Airbnb ROI: N/A

Traditional ROI: 2.21%

527 Heckathorn Church Rd

Seneca, PA

3 beds | N/A baths | 1,308 sq.ft.

$149,000

Airbnb cash on cash: 2.26%

Traditional cash on cash: 9.74%

Airbnb Rental Income: $1161

Traditional Rental Income: $1845

Airbnb ROI: 2.26%

Traditional ROI: 9.74%

539 Heckathorn Church Rd

Seneca, PA

4 beds | 2 baths | 2,580 sq.ft.

$349,900

Airbnb cash on cash: 0.31%

Traditional cash on cash: 6.68%

Airbnb Rental Income: $1148

Traditional Rental Income: $2861

Airbnb ROI: 0.31%

Traditional ROI: 6.68%

122 S Main St

Seneca, PA

1 beds | N/A baths | 2,700 sq.ft.

$139,900

Airbnb cash on cash: -2.24%

Traditional cash on cash: 7.14%

Airbnb Rental Income: $387

Traditional Rental Income: $1393

Airbnb ROI: -2.24%