Real Estate Investment Properties for Sale in Clio, SC

Looking for investment property in Clio, SC with high ROI ?

Explore a variety of short-term homes & houses in Clio, SC. Invest wisely with VRBO & Clio, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Clio, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
403 N Main St Clio, SC Beautifully preserved 1916 Colonial Revival farmhouse with expansive wraparound porches an...	5 beds \| 3 baths \| 3,484 sq.ft.	$299,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.7% Airbnb Rental Income: $null Traditional Rental Income: $3546 Airbnb ROI: N/A Traditional ROI: 10.7%
Investment Properties for Sale in Other Cities of South-carolina
10 Derby Court Bluffton , SC Exceptional Bluffton estate located at 10 Derby Court in Rose Dhu Plantation, Bluffton, SC...	5 beds \| 5 baths \| 4,812 sq.ft.	$3,525,600	Airbnb cash on cash: -0.7% Traditional cash on cash: -0.23% Airbnb Rental Income: $3743 Traditional Rental Income: $4447 Airbnb ROI: -0.7% Traditional ROI: -0.23%
40 Folly Field Road #B114 Hilton Head Island , SC Experience coastal living at its finest in this prime 1-bed, 1-bath condo at the highly so...	1 beds \| 1 baths \| 540 sq.ft.	$318,900	Airbnb cash on cash: -0.91% Traditional cash on cash: 1.07% Airbnb Rental Income: $576 Traditional Rental Income: $883 Airbnb ROI: -0.91% Traditional ROI: 1.07%
48 Salt Marsh Drive #48 Hilton Head Island , SC Perfectly positioned at the gateway to Hilton Head Island yet firmly rooted in the heart o...	4 beds \| 3 baths \| 1,250 sq.ft.	$345,000	Airbnb cash on cash: 6.46% Traditional cash on cash: 4.24% Airbnb Rental Income: $3460 Traditional Rental Income: $1976 Airbnb ROI: 6.46% Traditional ROI: 4.24%
1866 Capri Drive Charleston , SC This waterfront tidal creek home is only minutes from Downtown Charleston!! Capri Isle is ...	4 beds \| 3 baths \| 3,980 sq.ft.	$870,000	Airbnb cash on cash: 0.92% Traditional cash on cash: 2.27% Airbnb Rental Income: $2751 Traditional Rental Income: $3199 Airbnb ROI: 0.92% Traditional ROI: 2.27%
1811 Manigault Place Charleston , SC Located inside 526 west of the Ashley, 1811 Manigault Place delivers the kind of comfortab...	4 beds \| 3 baths \| 2,095 sq.ft.	$545,000	Airbnb cash on cash: 2.17% Traditional cash on cash: 3.98% Airbnb Rental Income: $2620 Traditional Rental Income: $2917 Airbnb ROI: 2.17% Traditional ROI: 3.98%
6114 Fieldstone Cir Charleston , SC Located in the highly desirable Village Green community, this exceptional brick veneer ran...	3 beds \| 2 baths \| 2,188 sq.ft.	$549,000	Airbnb cash on cash: 1.87% Traditional cash on cash: 3.29% Airbnb Rental Income: $2323 Traditional Rental Income: $2474 Airbnb ROI: 1.87% Traditional ROI: 3.29%
1679 Seabago Drive Charleston , SC Located in desired Bolton's Landing, this 4BR/3.5BA where the updates go unnoticed deliver...	4 beds \| 4 baths \| 2,710 sq.ft.	$600,000	Airbnb cash on cash: 1.33% Traditional cash on cash: 4.01% Airbnb Rental Income: $2286 Traditional Rental Income: $3219 Airbnb ROI: 1.33% Traditional ROI: 4.01%
130 River Landing Drive #3306 Daniel Island , SC Perched on the top level in the heart of Daniel Island, this inviting condo pairs easy, lo...	1 beds \| 1 baths \| 638 sq.ft.	$310,000	Airbnb cash on cash: 2.5% Traditional cash on cash: 3.22% Airbnb Rental Income: $1760 Traditional Rental Income: $1490 Airbnb ROI: 2.5% Traditional ROI: 3.22%
500 Bucksley Lane #207 Charleston , SC Beautiful 3 bed 2 bath condo on Daniel Island! Gourmet kitchen with quartz countertops, gr...	3 beds \| 2 baths \| 1,353 sq.ft.	$480,000	Airbnb cash on cash: 1.69% Traditional cash on cash: 3.14% Airbnb Rental Income: $2096 Traditional Rental Income: $2207 Airbnb ROI: 1.69% Traditional ROI: 3.14%
1049 Island Court Summerton , SC Furnished waterfront gem, located in Goat Island, nestled in the gated community of The Po...	3 beds \| 4 baths \| 1,652 sq.ft.	$395,000	Airbnb cash on cash: 0.16% Traditional cash on cash: 5.04% Airbnb Rental Income: $1115 Traditional Rental Income: $2547 Airbnb ROI: 0.16% Traditional ROI: 5.04%
10 N Avondale Drive Greenville , SC For more info, contact John Schroder. Enjoy the historic charm and character that defines ...	3 beds \| 3 baths \| 2,375 sq.ft.	$774,900	Airbnb cash on cash: 0.38% Traditional cash on cash: 1.66% Airbnb Rental Income: $1794 Traditional Rental Income: $2229 Airbnb ROI: 0.38% Traditional ROI: 1.66%
9401 OLD WHITE HORSE Road Greenville , SC MOVE IN READY! New Roof on Home and Barn (2026) - New HVAC systems (2025) Welcome to Your ...	4 beds \| 3 baths \| 2,827 sq.ft.	$849,900	Airbnb cash on cash: 0.94% Traditional cash on cash: 2.12% Airbnb Rental Income: $2413 Traditional Rental Income: $2755 Airbnb ROI: 0.94% Traditional ROI: 2.12%

Real Estate investment in Clio, SC

There are 1 properties for sale in the city of Clio . The median list price in Clio is $279,900 and the average price per square foot is $163. In June 2026, the average monthly cash on cash return in Clio is 43.00%. The average monthly rental income in Clio is $965.

Clio, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 1 investment properties available for sale in Clio.

In 2026, the best neighborhood to buy investment property is Clio.

The ROI for Long-Term is higher than the Short-Term in Clio with average rental income of $965.

Your search for investment property begins and ends here

Investment Property for Sale in Clio, SC

403 N Main St

Clio, SC

5 beds | 3 baths | 3,484 sq.ft.

$299,900

Airbnb cash on cash: N/A

Traditional cash on cash: 10.7%

Airbnb Rental Income: $null

Traditional Rental Income: $3546

Airbnb ROI: N/A

Traditional ROI: 10.7%

Investment Properties for Sale in Other Cities of South-carolina

Bluffton , SC

5 beds | 5 baths | 4,812 sq.ft.

$3,525,600

Airbnb cash on cash: -0.7%

Traditional cash on cash: -0.23%

Airbnb Rental Income: $3743

Traditional Rental Income: $4447

Airbnb ROI: -0.7%

Traditional ROI: -0.23%

Hilton Head Island , SC

1 beds | 1 baths | 540 sq.ft.

$318,900

Airbnb cash on cash: -0.91%

Traditional cash on cash: 1.07%

Airbnb Rental Income: $576

Traditional Rental Income: $883

Airbnb ROI: -0.91%

Traditional ROI: 1.07%

Hilton Head Island , SC

4 beds | 3 baths | 1,250 sq.ft.

$345,000

Airbnb cash on cash: 6.46%

Traditional cash on cash: 4.24%

Airbnb Rental Income: $3460

Traditional Rental Income: $1976

Airbnb ROI: 6.46%

Traditional ROI: 4.24%

Charleston , SC

4 beds | 3 baths | 3,980 sq.ft.

$870,000

Airbnb cash on cash: 0.92%

Traditional cash on cash: 2.27%

Airbnb Rental Income: $2751

Traditional Rental Income: $3199

Airbnb ROI: 0.92%

Traditional ROI: 2.27%

Charleston , SC

4 beds | 3 baths | 2,095 sq.ft.

$545,000

Airbnb cash on cash: 2.17%

Traditional cash on cash: 3.98%

Airbnb Rental Income: $2620

Traditional Rental Income: $2917

Airbnb ROI: 2.17%

Traditional ROI: 3.98%

Charleston , SC

3 beds | 2 baths | 2,188 sq.ft.

$549,000

Airbnb cash on cash: 1.87%

Traditional cash on cash: 3.29%

Airbnb Rental Income: $2323

Traditional Rental Income: $2474

Airbnb ROI: 1.87%

Traditional ROI: 3.29%

Charleston , SC

4 beds | 4 baths | 2,710 sq.ft.

$600,000

Airbnb cash on cash: 1.33%

Traditional cash on cash: 4.01%

Airbnb Rental Income: $2286

Traditional Rental Income: $3219

Airbnb ROI: 1.33%

Traditional ROI: 4.01%

Daniel Island , SC

1 beds | 1 baths | 638 sq.ft.

$310,000

Airbnb cash on cash: 2.5%

Traditional cash on cash: 3.22%