Real Estate Investment Properties for Sale in Florence, SC

Looking for investment property in Florence, SC with high ROI ?

Explore a variety of short-term homes & houses in Florence, SC. Invest wisely with VRBO & Florence, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Florence, SC

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1914 Deerwood Place Florence, SC Welcome to 1914 Deerwood Place, a beautifully updated home tucked away on a quiet cul-de-s...	4 beds \| 3 baths \| 2,696 sq.ft.	$419,900	Airbnb cash on cash: 2.59% Traditional cash on cash: 5.8% Airbnb Rental Income: $2095 Traditional Rental Income: $2819 Airbnb ROI: 2.59% Traditional ROI: 5.8%
1671 Lake Wateree Drive Florence, SC Immaculate brick home located in the desirable West Lakes subdivision in Florence, SC, rea...	4 beds \| 3 baths \| 3,086 sq.ft.	$399,900	Airbnb cash on cash: 2.34% Traditional cash on cash: 5.29% Airbnb Rental Income: $2095 Traditional Rental Income: $2663 Airbnb ROI: 2.34% Traditional ROI: 5.29%
4178 Rodanthe Cir Florence, SC Welcome home to Rodanthe Circle! This is a bright and spacious 4-bedroom, 2-bathroom home ...	4 beds \| 2 baths \| 2,958 sq.ft.	$399,950	Airbnb cash on cash: 2.34% Traditional cash on cash: 4.59% Airbnb Rental Income: $2095 Traditional Rental Income: $2403 Airbnb ROI: 2.34% Traditional ROI: 4.59%
3241 Lakeshore Drive Florence, SC Discover your perfect 4000 sq-ft, lakefront sanctuary in this stunning four-bedroom, four-...	4 beds \| 5 baths \| 4,000 sq.ft.	$799,000	Airbnb cash on cash: 0.4% Traditional cash on cash: 5.43% Airbnb Rental Income: $2095 Traditional Rental Income: $5299 Airbnb ROI: 0.4% Traditional ROI: 5.43%
151 Harrell Street Florence, SC Three bedroom and one bathroom home with over 1,000 sq ft sitting on a corner lot within t...	3 beds \| 1 baths \| 1,170 sq.ft.	$170,000	Airbnb cash on cash: 4.04% Traditional cash on cash: 6.11% Airbnb Rental Income: $1429 Traditional Rental Income: $1338 Airbnb ROI: 4.04% Traditional ROI: 6.11%
1007 W Palmetto St Florence, SC Step back in time with this 1933 Tudor-style landmark. This architectural treasure feature...	4 beds \| 4 baths \| 4,336 sq.ft.	$310,000	Airbnb cash on cash: 3.45% Traditional cash on cash: 11.16% Airbnb Rental Income: $2095 Traditional Rental Income: $3806 Airbnb ROI: 3.45% Traditional ROI: 11.16%
1716 Furman Drive Florence, SC Welcome home to 1716 Furman Drive in College Park! Perfectly located in the heart of Flore...	3 beds \| 2 baths \| 1,658 sq.ft.	$249,900	Airbnb cash on cash: 2.28% Traditional cash on cash: 6.03% Airbnb Rental Income: $1429 Traditional Rental Income: $1886 Airbnb ROI: 2.28% Traditional ROI: 6.03%
1031 Royal Street Florence, SC Looking for a unique opportunity? This is it! Great investment property that is ideally lo...	3 beds \| 1 baths \| 925 sq.ft.	$110,000	Airbnb cash on cash: 6.97% Traditional cash on cash: 8.99% Airbnb Rental Income: $1429 Traditional Rental Income: $1218 Airbnb ROI: 6.97% Traditional ROI: 8.99%
900 Sanborn Street Florence, SC Looking for a Unique Opportunity? Well, this is it! Great investment property that is idea...	3 beds \| 1 baths \| 1,065 sq.ft.	$118,000	Airbnb cash on cash: 6.41% Traditional cash on cash: 9.27% Airbnb Rental Income: $1429 Traditional Rental Income: $1328 Airbnb ROI: 6.41% Traditional ROI: 9.27%
308 E Summit Circle Florence, SC Contact the listing agent to schedule all showings. The Property Manager coordinates all a...	3 beds \| 2 baths \| 1,025 sq.ft.	$139,000	Airbnb cash on cash: 5.25% Traditional cash on cash: 10.35% Airbnb Rental Income: $1429 Traditional Rental Income: $1683 Airbnb ROI: 5.25% Traditional ROI: 10.35%
4133 Enclave Drive Florence, SC What an amazing property-completely custom and move-in ready! This home features a desirab...	4 beds \| 3 baths \| 2,550 sq.ft.	$469,900	Airbnb cash on cash: 1.76% Traditional cash on cash: 3.31% Airbnb Rental Income: $2095 Traditional Rental Income: $2236 Airbnb ROI: 1.76% Traditional ROI: 3.31%
1431 Bourbon Drive Florence, SC Why wait for new construction when you can own this beautifully maintained, move-in ready ...	3 beds \| 2 baths \| 1,665 sq.ft.	$289,900	Airbnb cash on cash: 1.76% Traditional cash on cash: 4.87% Airbnb Rental Income: $1429 Traditional Rental Income: $1850 Airbnb ROI: 1.76% Traditional ROI: 4.87%
2109 Eaton Cir Florence, SC Renovated 2 years ago, 3 bedrooms, 1 /12 baths, all brick home, all new updated electric p...	3 beds \| 2 baths \| 1,154 sq.ft.	$209,900	Airbnb cash on cash: 3% Traditional cash on cash: 5.39% Airbnb Rental Income: $1429 Traditional Rental Income: $1479 Airbnb ROI: 3% Traditional ROI: 5.39%
3326 Lakeshore Drive Florence, SC Welcome to the charm and comfort of Forest Lake living in this beautiful 4 to 5 bedroom, 3...	5 beds \| 4 baths \| 3,798 sq.ft.	$569,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.09% Airbnb Rental Income: $null Traditional Rental Income: $2571 Airbnb ROI: N/A Traditional ROI: 3.09%
130 Mustang Rd Florence, SC 2 Brick Ranch Homes---1) Home 3/1 Super Nice inside & 1 - Brick Ranch Home 3/2 coming avai...	3 beds \| 1 baths \| 1,316 sq.ft.	$449,900	Airbnb cash on cash: 0.79% Traditional cash on cash: 1.63% Airbnb Rental Income: $1429 Traditional Rental Income: $1356 Airbnb ROI: 0.79% Traditional ROI: 1.63%
912 Camp Wiggins Rd. Florence, SC Enjoy the freedom of country living with NO HOA in this spaciously renovated brick home si...	3 beds \| 2 baths \| 2,028 sq.ft.	$285,000	Airbnb cash on cash: 1.82% Traditional cash on cash: 5.46% Airbnb Rental Income: $1429 Traditional Rental Income: $1979 Airbnb ROI: 1.82% Traditional ROI: 5.46%
1017 Alton Circle Florence, SC Located in one of Florence's established neighborhoods known for its walkability and bike-...	4 beds \| 3 baths \| 2,312 sq.ft.	$324,500	Airbnb cash on cash: 3.23% Traditional cash on cash: 5.71% Airbnb Rental Income: $2095 Traditional Rental Income: $2314 Airbnb ROI: 3.23% Traditional ROI: 5.71%
1819 Hazel Dr. Florence, SC Welcome to this beautifully remodeled open-concept home offering space, flexibility, and m...	4 beds \| 2 baths \| 2,232 sq.ft.	$415,000	Airbnb cash on cash: 2.01% Traditional cash on cash: 2.02% Airbnb Rental Income: $2095 Traditional Rental Income: $1561 Airbnb ROI: 2.01% Traditional ROI: 2.02%
313 S Gaillard St Florence, SC Three bedroom oand one bathroom home in Florence, SC is seconds from McLeod Hospital. With...	3 beds \| 1 baths \| 1,074 sq.ft.	$165,000	Airbnb cash on cash: 4.48% Traditional cash on cash: 6.99% Airbnb Rental Income: $1429 Traditional Rental Income: $1396 Airbnb ROI: 4.48% Traditional ROI: 6.99%
1454 Dorchester Road Florence, SC Stunning designer brick home situated on a premium, oversized corner lot! Every detail exu...	3 beds \| 3 baths \| 2,529 sq.ft.	$439,000	Airbnb cash on cash: 0.64% Traditional cash on cash: 3.8% Airbnb Rental Income: $1429 Traditional Rental Income: $2300 Airbnb ROI: 0.64% Traditional ROI: 3.8%
713 Bellemeade Circle Florence, SC Welcome to Wessex. This 4-bedroom, 3-bath home offers an open floor plan with functional s...	4 beds \| 3 baths \| 2,803 sq.ft.	$409,900	Airbnb cash on cash: 2.43% Traditional cash on cash: 5.2% Airbnb Rental Income: $2095 Traditional Rental Income: $2619 Airbnb ROI: 2.43% Traditional ROI: 5.2%

Real Estate investment in Florence, SC

There are 281 properties for sale in the city of Florence . The median list price in Florence is $290,441 and the average price per square foot is $141. In October 2026, the average monthly cash on cash return in Florence is 6.00%. The average monthly rental income in Florence is $2,088.

Florence, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 281 investment properties available for sale in Florence.

In 2026, the best neighborhood to buy investment property is Florence.

The ROI for Long-Term is higher than the Short-Term in Florence with average rental income of $2,088.

Your search for investment property begins and ends here

Investment Property for Sale in Florence, SC

1914 Deerwood Place

Florence, SC

4 beds | 3 baths | 2,696 sq.ft.

$419,900

Airbnb cash on cash: 2.59%

Traditional cash on cash: 5.8%

Airbnb Rental Income: $2095

Traditional Rental Income: $2819

Airbnb ROI: 2.59%

Traditional ROI: 5.8%

1671 Lake Wateree Drive

Florence, SC

4 beds | 3 baths | 3,086 sq.ft.

$399,900

Airbnb cash on cash: 2.34%

Traditional cash on cash: 5.29%

Airbnb Rental Income: $2095

Traditional Rental Income: $2663

Airbnb ROI: 2.34%

Traditional ROI: 5.29%

4178 Rodanthe Cir

Florence, SC

4 beds | 2 baths | 2,958 sq.ft.

$399,950

Airbnb cash on cash: 2.34%

Traditional cash on cash: 4.59%

Airbnb Rental Income: $2095

Traditional Rental Income: $2403

Airbnb ROI: 2.34%

Traditional ROI: 4.59%

3241 Lakeshore Drive

Florence, SC

4 beds | 5 baths | 4,000 sq.ft.

$799,000

Airbnb cash on cash: 0.4%

Traditional cash on cash: 5.43%

Airbnb Rental Income: $2095

Traditional Rental Income: $5299

Airbnb ROI: 0.4%

Traditional ROI: 5.43%

151 Harrell Street

Florence, SC

3 beds | 1 baths | 1,170 sq.ft.

$170,000

Airbnb cash on cash: 4.04%

Traditional cash on cash: 6.11%

Airbnb Rental Income: $1429

Traditional Rental Income: $1338

Airbnb ROI: 4.04%

Traditional ROI: 6.11%

1007 W Palmetto St

Florence, SC

4 beds | 4 baths | 4,336 sq.ft.

$310,000

Airbnb cash on cash: 3.45%

Traditional cash on cash: 11.16%

Airbnb Rental Income: $2095

Traditional Rental Income: $3806

Airbnb ROI: 3.45%

Traditional ROI: 11.16%

1716 Furman Drive

Florence, SC

3 beds | 2 baths | 1,658 sq.ft.

$249,900

Airbnb cash on cash: 2.28%

Traditional cash on cash: 6.03%

Airbnb Rental Income: $1429

Traditional Rental Income: $1886

Airbnb ROI: 2.28%

Traditional ROI: 6.03%

1031 Royal Street

Florence, SC

3 beds | 1 baths | 925 sq.ft.

$110,000

Airbnb cash on cash: 6.97%

Traditional cash on cash: 8.99%

Airbnb Rental Income: $1429

Traditional Rental Income: $1218

Airbnb ROI: 6.97%