Real Estate Investment Properties for Sale in Florence, SC

Looking for investment property in Florence, SC with high ROI ?

Explore a variety of short-term homes & houses in Florence, SC. Invest wisely with VRBO & Florence, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Florence, SC

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
3016 Greystone Cir Florence, SC Looking for a home with plenty of room to grow? This spacious property could be exactly wh...	3 beds \| 2 baths \| 1,931 sq.ft.	$214,000	Airbnb cash on cash: 1.12% Traditional cash on cash: 7.88% Airbnb Rental Income: $1116 Traditional Rental Income: $2112 Airbnb ROI: 1.12% Traditional ROI: 7.88%
1225 Oakdale Dr Florence, SC Cute and cozy off the beaten path, you will find this gem that needs some polishing. 3 Be...	3 beds \| 2 baths \| 1,224 sq.ft.	$199,900	Airbnb cash on cash: 1.56% Traditional cash on cash: 4.74% Airbnb Rental Income: $1116 Traditional Rental Income: $1402 Airbnb ROI: 1.56% Traditional ROI: 4.74%
37 York St Florence, SC Buy through Auction.com. This property is being offered for sale exclusively on Auction.co...	7 beds \| 3 baths \| 4,174 sq.ft.	$449,999	Airbnb cash on cash: N/A Traditional cash on cash: 3.98% Airbnb Rental Income: $null Traditional Rental Income: $2431 Airbnb ROI: N/A Traditional ROI: 3.98%
1505 E Mciver Rd Florence, SC Charming Starter Home with Endless Potential! Welcome to your new adventure in homeown...	4 beds \| 2 baths \| 1,748 sq.ft.	$289,000	Airbnb cash on cash: 2.66% Traditional cash on cash: 4.67% Airbnb Rental Income: $1889 Traditional Rental Income: $1933 Airbnb ROI: 2.66% Traditional ROI: 4.67%
2151 Bonnie Dr Florence, SC Welcome to the great outdoors at 2151 Bonnie Dr. This new construction, 4 bedroom, 3.5 bat...	4 beds \| 3 baths \| 3,284 sq.ft.	$575,000	Airbnb cash on cash: 1.28% Traditional cash on cash: 4.71% Airbnb Rental Income: $1889 Traditional Rental Income: $3225 Airbnb ROI: 1.28% Traditional ROI: 4.71%
278 Timberlake Dr Florence, SC 278 Timberlake Dr, Florence, SC 29501 \| Other	N/A beds \| N/A baths \| N/A	$75,000	Airbnb cash on cash: -1.11% Traditional cash on cash: 3.13% Airbnb Rental Income: $382 Traditional Rental Income: $463 Airbnb ROI: -1.11% Traditional ROI: 3.13%
12 Bayswater Rd Florence, SC 12 Bayswater Rd, Florence, SC 29506 \| Single Family Residential	4 beds \| 2 baths \| 2,499 sq.ft.	$199,900	Airbnb cash on cash: 5.24% Traditional cash on cash: 7.39% Airbnb Rental Income: $1889 Traditional Rental Income: $1792 Airbnb ROI: 5.24% Traditional ROI: 7.39%
89 Kings Rd Florence, SC 89 Kings Rd, Florence, SC 29506 \| Single Family Residential	4 beds \| 3 baths \| 2,450 sq.ft.	$449,500	Airbnb cash on cash: 1.5% Traditional cash on cash: 3.36% Airbnb Rental Income: $1889 Traditional Rental Income: $2166 Airbnb ROI: 1.5% Traditional ROI: 3.36%
TBD Goose Pond Ln (tract 1) Florence, SC TBD Goose Pond Ln (tract 1), Florence, SC 29506 \| Other	N/A beds \| N/A baths \| 2,217 sq.ft.	$110,000	Airbnb cash on cash: -1.23% Traditional cash on cash: 1.9% Airbnb Rental Income: $382 Traditional Rental Income: $463 Airbnb ROI: -1.23% Traditional ROI: 1.9%
Nile Plan Florence, SC Nile Plan, Florence, SC 29501 \| Single Family Residential	4 beds \| 3 baths \| 2,829 sq.ft.	$374,900	Airbnb cash on cash: 2.11% Traditional cash on cash: 4.45% Airbnb Rental Income: $1889 Traditional Rental Income: $2211 Airbnb ROI: 2.11% Traditional ROI: 4.45%
Reedy Plan Florence, SC Reedy Plan, Florence, SC 29501 \| Single Family Residential	4 beds \| 3 baths \| 2,772 sq.ft.	$374,900	Airbnb cash on cash: 2.11% Traditional cash on cash: 4.45% Airbnb Rental Income: $1889 Traditional Rental Income: $2211 Airbnb ROI: 2.11% Traditional ROI: 4.45%
Saluda Plan Florence, SC Saluda Plan, Florence, SC 29501 \| Single Family Residential	5 beds \| 3 baths \| 2,916 sq.ft.	$379,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.6% Airbnb Rental Income: $null Traditional Rental Income: $2289 Airbnb ROI: N/A Traditional ROI: 4.6%
Riviera Plan Florence, SC Riviera Plan, Florence, SC 29501 \| Single Family Residential	4 beds \| 2 baths \| 2,205 sq.ft.	$339,900	Airbnb cash on cash: 2.48% Traditional cash on cash: 3.7% Airbnb Rental Income: $1889 Traditional Rental Income: $1776 Airbnb ROI: 2.48% Traditional ROI: 3.7%
3115 Crestview Dr Florence, SC Welcome to 3115 Crestview Dr in Florence, a very tastefully updated home that has been com...	3 beds \| 2 baths \| 1,043 sq.ft.	$175,000	Airbnb cash on cash: 2.32% Traditional cash on cash: 7.69% Airbnb Rental Income: $1116 Traditional Rental Income: $1636 Airbnb ROI: 2.32% Traditional ROI: 7.69%
3738 Bromfield St Florence, SC *2.25%* Fully Assumable VA mortgage. Custom built home, elegant trim work, 10ft ceilin...	3 beds \| 2 baths \| 1,530 sq.ft.	$262,000	Airbnb cash on cash: 0.93% Traditional cash on cash: 5.21% Airbnb Rental Income: $1116 Traditional Rental Income: $1853 Airbnb ROI: 0.93% Traditional ROI: 5.21%

Real Estate investment in Florence, SC

There are 18 properties for sale in the city of Florence . The median list price in Florence is $280,335 and the average price per square foot is $135. In March 2026, the average monthly cash on cash return in Florence is 6.00%. The average monthly rental income in Florence is $2,065.

Florence, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 18 investment properties available for sale in Florence.

In 2026, the best neighborhood to buy investment property is Florence.

The ROI for Long-Term is higher than the Short-Term in Florence with average rental income of $2,065.

Your search for investment property begins and ends here

Investment Property for Sale in Florence, SC

3016 Greystone Cir

Florence, SC

3 beds | 2 baths | 1,931 sq.ft.

$214,000

Airbnb cash on cash: 1.12%

Traditional cash on cash: 7.88%

Airbnb Rental Income: $1116

Traditional Rental Income: $2112

Airbnb ROI: 1.12%

Traditional ROI: 7.88%

1225 Oakdale Dr

Florence, SC

3 beds | 2 baths | 1,224 sq.ft.

$199,900

Airbnb cash on cash: 1.56%

Traditional cash on cash: 4.74%

Airbnb Rental Income: $1116

Traditional Rental Income: $1402

Airbnb ROI: 1.56%

Traditional ROI: 4.74%

37 York St

Florence, SC

7 beds | 3 baths | 4,174 sq.ft.

$449,999

Airbnb cash on cash: N/A

Traditional cash on cash: 3.98%

Airbnb Rental Income: $null

Traditional Rental Income: $2431

Airbnb ROI: N/A

Traditional ROI: 3.98%

1505 E Mciver Rd

Florence, SC

4 beds | 2 baths | 1,748 sq.ft.

$289,000

Airbnb cash on cash: 2.66%

Traditional cash on cash: 4.67%

Airbnb Rental Income: $1889

Traditional Rental Income: $1933

Airbnb ROI: 2.66%

Traditional ROI: 4.67%

2151 Bonnie Dr

Florence, SC

4 beds | 3 baths | 3,284 sq.ft.

$575,000

Airbnb cash on cash: 1.28%

Traditional cash on cash: 4.71%

Airbnb Rental Income: $1889

Traditional Rental Income: $3225

Airbnb ROI: 1.28%

Traditional ROI: 4.71%

278 Timberlake Dr

Florence, SC

N/A beds | N/A baths | N/A

$75,000

Airbnb cash on cash: -1.11%

Traditional cash on cash: 3.13%

Airbnb Rental Income: $382

Traditional Rental Income: $463

Airbnb ROI: -1.11%

Traditional ROI: 3.13%

12 Bayswater Rd

Florence, SC

4 beds | 2 baths | 2,499 sq.ft.

$199,900

Airbnb cash on cash: 5.24%

Traditional cash on cash: 7.39%

Airbnb Rental Income: $1889

Traditional Rental Income: $1792

Airbnb ROI: 5.24%

Traditional ROI: 7.39%

89 Kings Rd

Florence, SC

4 beds | 3 baths | 2,450 sq.ft.

$449,500

Airbnb cash on cash: 1.5%

Traditional cash on cash: 3.36%

Airbnb Rental Income: $1889

Traditional Rental Income: $2166

Airbnb ROI: 1.5%