Real Estate Investment Properties for Sale in Salem, SC

Looking for investment property in Salem, SC with high ROI ?

Explore a variety of short-term homes & houses in Salem, SC. Invest wisely with VRBO & Salem, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Salem, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
21 Anchorage Lane Salem, SC Set within the premier gated community of Keowee Key, where lake living meets the foothill...	4 beds \| 3 baths \| N/A	$390,000	Airbnb cash on cash: -0.22% Traditional cash on cash: 4.56% Airbnb Rental Income: $1340 Traditional Rental Income: $2720 Airbnb ROI: -0.22% Traditional ROI: 4.56%
321 Coveview Court Salem, SC Start enjoying Lake Life from this MOSTLY FURNISHED KEOWEE KEY MARINA VILLAS CONDO located...	2 beds \| 3 baths \| 1,750 sq.ft.	$439,900	Airbnb cash on cash: 0.55% Traditional cash on cash: 2.09% Airbnb Rental Income: $1657 Traditional Rental Income: $1839 Airbnb ROI: 0.55% Traditional ROI: 2.09%
202 Hearthstone Way Salem, SC Welcome to 202 Hearthstone Way at The Cliffs at Keowee Falls. Magnificent mountain and lak...	4 beds \| 6 baths \| 4,900 sq.ft.	$2,599,000	Airbnb cash on cash: -0.91% Traditional cash on cash: 1.11% Airbnb Rental Income: $1340 Traditional Rental Income: $5807 Airbnb ROI: -0.91% Traditional ROI: 1.11%
11 Captain Lane Salem, SC Exceptional Price Per Square Foot in Keowee Key - Room to Renovate and Make It Your Own! W...	3 beds \| 2 baths \| N/A	$449,000	Airbnb cash on cash: -1.13% Traditional cash on cash: 2.71% Airbnb Rental Income: $1255 Traditional Rental Income: $2545 Airbnb ROI: -1.13% Traditional ROI: 2.71%
272 Jocassee Ridge Way Salem, SC MAGNIFICANT MOUNTAIN VIEWS from almost every room in the home. Located on a 1.55 acre lot ...	4 beds \| 5 baths \| 4,283 sq.ft.	$699,900	Airbnb cash on cash: -0.54% Traditional cash on cash: 3.64% Airbnb Rental Income: $1340 Traditional Rental Income: $3751 Airbnb ROI: -0.54% Traditional ROI: 3.64%
N-35A Meadow View Way Salem, SC Are you Searching for that perfect mountain view home surrounded by Mother Nature's gifts ...	4 beds \| 4 baths \| N/A	$1,095,077	Airbnb cash on cash: -0.8% Traditional cash on cash: 1.49% Airbnb Rental Income: $1340 Traditional Rental Income: $3261 Airbnb ROI: -0.8% Traditional ROI: 1.49%
605 River Birch Way Salem, SC Discover refined mountain-lake living in The Retreat enclave of The Cliffs at Keowee Falls...	4 beds \| 4 baths \| 2,421 sq.ft.	$1,179,000	Airbnb cash on cash: -0.8% Traditional cash on cash: 1.4% Airbnb Rental Income: $1340 Traditional Rental Income: $3339 Airbnb ROI: -0.8% Traditional ROI: 1.4%
491 Tall Ship Drive unit: 326 Salem, SC Welcome to Tall Ship Building 491 Unit 326, a beautifully updated corner condo with stunni...	2 beds \| 2 baths \| 1,460 sq.ft.	$424,900	Airbnb cash on cash: 0.2% Traditional cash on cash: 3% Airbnb Rental Income: $1657 Traditional Rental Income: $2305 Airbnb ROI: 0.2% Traditional ROI: 3%
259 W Main Street Salem, SC Experience peaceful country living with convenience and charm in this meticulously maintai...	3 beds \| 2 baths \| 2,176 sq.ft.	$295,000	Airbnb cash on cash: 1.63% Traditional cash on cash: 6.06% Airbnb Rental Income: $1255 Traditional Rental Income: $2086 Airbnb ROI: 1.63% Traditional ROI: 6.06%
30 Gulf Stream Lane Salem, SC Originally constructed in 2002 in Keowee Key as a small home on one site for a young famil...	4 beds \| 5 baths \| N/A	$1,080,000	Airbnb cash on cash: -0.54% Traditional cash on cash: 3.19% Airbnb Rental Income: $1340 Traditional Rental Income: $5016 Airbnb ROI: -0.54% Traditional ROI: 3.19%
213 Shipmaster Drive Salem, SC Welcome to 213 Shipmaster Drive, a beautifully maintained home nestled on a 1.6-acre estat...	4 beds \| 4 baths \| 3,130 sq.ft.	$739,000	Airbnb cash on cash: -0.03% Traditional cash on cash: 3.34% Airbnb Rental Income: $1340 Traditional Rental Income: $3284 Airbnb ROI: -0.03% Traditional ROI: 3.34%
400-1 Captains Walk Circle Salem, SC Live the Lake Keowee Resort Lifestyle here at 400 Captains Walk Circle, Unit 1 - Keowee Ke...	2 beds \| 1 baths \| 768 sq.ft.	$219,000	Airbnb cash on cash: 3.8% Traditional cash on cash: 4.41% Airbnb Rental Income: $1657 Traditional Rental Income: $1320 Airbnb ROI: 3.8% Traditional ROI: 4.41%
18 Mainsail Drive Salem, SC Welcome to the gated community of Keowee Key. Enjoy the 4 seasons with close proximity to ...	3 beds \| 3 baths \| N/A	$615,000	Airbnb cash on cash: 0.13% Traditional cash on cash: 2.98% Airbnb Rental Income: $1255 Traditional Rental Income: $2518 Airbnb ROI: 0.13% Traditional ROI: 2.98%
505 Long Reach Drive Salem, SC Welcome to 505 Long Reach Drive, a home that feels like it was made just for you, where cl...	4 beds \| 3 baths \| N/A	$650,000	Airbnb cash on cash: -0.27% Traditional cash on cash: 2.59% Airbnb Rental Income: $1340 Traditional Rental Income: $2765 Airbnb ROI: -0.27% Traditional ROI: 2.59%
338 Long Cove Trail Salem, SC Rare Find Built in 2023 Lake Keowee Waterfront Custom Home on the MAIN CHANNEL with a PRIV...	4 beds \| 4 baths \| 3,415 sq.ft.	$2,299,900	Airbnb cash on cash: -1.08% Traditional cash on cash: 0.03% Airbnb Rental Income: $1255 Traditional Rental Income: $3373 Airbnb ROI: -1.08% Traditional ROI: 0.03%
207 S Reach Lane Salem, SC Here is your opportunity to live on Lake Keowee. Home is located in the South Reach enclav...	2 beds \| 2 baths \| 3,192 sq.ft.	$999,000	Airbnb cash on cash: -0.16% Traditional cash on cash: 0.65% Airbnb Rental Income: $1657 Traditional Rental Income: $2076 Airbnb ROI: -0.16% Traditional ROI: 0.65%
487 Tall Ship Drive unit: 121 Salem, SC Start enjoying Lake Life from this FURNISHED KEOWEE KEY TALL SHIP CONDO located in the Cut...	2 beds \| 2 baths \| 1,462 sq.ft.	$349,900	Airbnb cash on cash: 1.12% Traditional cash on cash: 4.05% Airbnb Rental Income: $1657 Traditional Rental Income: $2197 Airbnb ROI: 1.12% Traditional ROI: 4.05%
48 Commodore Drive Salem, SC Welcome to 48 Commodore Drive in Salem, South Carolina, a well-appointed home offering fle...	3 beds \| 3 baths \| N/A	$449,999	Airbnb cash on cash: 0.36% Traditional cash on cash: 3.88% Airbnb Rental Income: $1255 Traditional Rental Income: $2392 Airbnb ROI: 0.36% Traditional ROI: 3.88%
320 Knollwood Drive Salem, SC Experience the pinnacle of waterfront living in this custom-built masterpiece, perfectly p...	5 beds \| 5 baths \| N/A	$3,800,000	Airbnb cash on cash: -1.45% Traditional cash on cash: -0.28% Airbnb Rental Income: $908 Traditional Rental Income: $4688 Airbnb ROI: -1.45% Traditional ROI: -0.28%
9 Anchorage Lane Salem, SC Completely updated and move-in ready, this stunning home is ideally located in the heart o...	3 beds \| 3 baths \| 2,557 sq.ft.	$725,000	Airbnb cash on cash: -0.13% Traditional cash on cash: 2.32% Airbnb Rental Income: $1255 Traditional Rental Income: $2513 Airbnb ROI: -0.13% Traditional ROI: 2.32%
102 Jocassee Falls Road Salem, SC Inviting Mountain Retreat Near Lake Jocassee - STR Friendly Discover privacy, comfort, and...	4 beds \| 2 baths \| 2,234 sq.ft.	$699,000	Airbnb cash on cash: -0.75% Traditional cash on cash: 1.45% Airbnb Rental Income: $1340 Traditional Rental Income: $2363 Airbnb ROI: -0.75% Traditional ROI: 1.45%
1 Pine Garden Circle Salem, SC Keowee Key Interior Home TO BE BUILT located near South Gate. The Bluebird Three Plan w/ B...	3 beds \| 3 baths \| 3,347 sq.ft.	$699,900	Airbnb cash on cash: -0.6% Traditional cash on cash: 1.56% Airbnb Rental Income: $1255 Traditional Rental Income: $2268 Airbnb ROI: -0.6% Traditional ROI: 1.56%

Real Estate investment in Salem, SC

There are 35 properties for sale in the city of Salem . The median list price in Salem is $276,030 and the average price per square foot is $186. In March 2026, the average monthly cash on cash return in Salem is 2.00%. The average monthly rental income in Salem is $1,949.

Salem, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 35 investment properties available for sale in Salem.

In 2026, the best neighborhood to buy investment property is Salem.

The ROI for Short-Term is higher than the Long-Term in Salem with average rental income of $1,340.

Your search for investment property begins and ends here

Investment Property for Sale in Salem, SC

21 Anchorage Lane

Salem, SC

4 beds | 3 baths | N/A

$390,000

Airbnb cash on cash: -0.22%

Traditional cash on cash: 4.56%

Airbnb Rental Income: $1340

Traditional Rental Income: $2720

Airbnb ROI: -0.22%

Traditional ROI: 4.56%

321 Coveview Court

Salem, SC

2 beds | 3 baths | 1,750 sq.ft.

$439,900

Airbnb cash on cash: 0.55%

Traditional cash on cash: 2.09%

Airbnb Rental Income: $1657

Traditional Rental Income: $1839

Airbnb ROI: 0.55%

Traditional ROI: 2.09%

202 Hearthstone Way

Salem, SC

4 beds | 6 baths | 4,900 sq.ft.

$2,599,000

Airbnb cash on cash: -0.91%

Traditional cash on cash: 1.11%

Airbnb Rental Income: $1340

Traditional Rental Income: $5807

Airbnb ROI: -0.91%

Traditional ROI: 1.11%

11 Captain Lane

Salem, SC

3 beds | 2 baths | N/A

$449,000

Airbnb cash on cash: -1.13%

Traditional cash on cash: 2.71%

Airbnb Rental Income: $1255

Traditional Rental Income: $2545

Airbnb ROI: -1.13%

Traditional ROI: 2.71%

272 Jocassee Ridge Way

Salem, SC

4 beds | 5 baths | 4,283 sq.ft.

$699,900

Airbnb cash on cash: -0.54%

Traditional cash on cash: 3.64%

Airbnb Rental Income: $1340

Traditional Rental Income: $3751

Airbnb ROI: -0.54%

Traditional ROI: 3.64%

N-35A Meadow View Way

Salem, SC

4 beds | 4 baths | N/A

$1,095,077

Airbnb cash on cash: -0.8%

Traditional cash on cash: 1.49%

Airbnb Rental Income: $1340

Traditional Rental Income: $3261

Airbnb ROI: -0.8%

Traditional ROI: 1.49%

605 River Birch Way

Salem, SC

4 beds | 4 baths | 2,421 sq.ft.

$1,179,000

Airbnb cash on cash: -0.8%

Traditional cash on cash: 1.4%

Airbnb Rental Income: $1340

Traditional Rental Income: $3339

Airbnb ROI: -0.8%

Traditional ROI: 1.4%

491 Tall Ship Drive unit: 326

Salem, SC

2 beds | 2 baths | 1,460 sq.ft.

$424,900

Airbnb cash on cash: 0.2%

Traditional cash on cash: 3%

Airbnb Rental Income: $1657

Traditional Rental Income: $2305

Airbnb ROI: 0.2%