Real Estate Investment Properties for Sale in Seneca, SC

Looking for investment property in Seneca, SC with high ROI ?

Explore a variety of short-term homes & houses in Seneca, SC. Invest wisely with VRBO & Seneca, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1006 Kaye Street Seneca, SC Charming Brick Ranch on 1.55 Acres in Prime Seneca Location. The Seller is in the process ...	3 beds \| 3 baths \| 1,889 sq.ft.	$299,000	Airbnb cash on cash: 2.35% Traditional cash on cash: 6.54% Airbnb Rental Income: $1513 Traditional Rental Income: $2251 Airbnb ROI: 2.35% Traditional ROI: 6.54%
4306 Ashford Bluff Drive Seneca, SC Ready for a new family and move-in ready. Welcome to 4306 Ashford Bluff Dr., Seneca, SC. A...	3 beds \| 3 baths \| 3,144 sq.ft.	$590,000	Airbnb cash on cash: 0.21% Traditional cash on cash: 2.58% Airbnb Rental Income: $1513 Traditional Rental Income: $2377 Airbnb ROI: 0.21% Traditional ROI: 2.58%
256 Terrace View Way Seneca, SC The spacious home offers three large bedrooms and two full baths on the main level, as wel...	3 beds \| 2 baths \| 1,927 sq.ft.	$340,000	Airbnb cash on cash: 1.82% Traditional cash on cash: 5.66% Airbnb Rental Income: $1513 Traditional Rental Income: $2300 Airbnb ROI: 1.82% Traditional ROI: 5.66%
208 Terrace View Way Seneca, SC Looking for a move-in-ready 3-bedroom home in Shadowood subdivision near Clemson Universit...	3 beds \| 2 baths \| N/A	$340,000	Airbnb cash on cash: 1.73% Traditional cash on cash: 4.68% Airbnb Rental Income: $1513 Traditional Rental Income: $2015 Airbnb ROI: 1.73% Traditional ROI: 4.68%
216 Riverbank Court Seneca, SC Don't miss this rare opportunity to own a beautifully crafted, Troyer built home in the de...	3 beds \| 3 baths \| 3,300 sq.ft.	$419,900	Airbnb cash on cash: 0.9% Traditional cash on cash: 3.61% Airbnb Rental Income: $1513 Traditional Rental Income: $2136 Airbnb ROI: 0.9% Traditional ROI: 3.61%
1298 Carradine Road Seneca, SC 1298 Carradine Road is a treasure nestled in a serene, wooded, lake community of Lake Hart...	3 beds \| 3 baths \| 2,146 sq.ft.	$405,000	Airbnb cash on cash: 1.16% Traditional cash on cash: 3.92% Airbnb Rental Income: $1513 Traditional Rental Income: $2118 Airbnb ROI: 1.16% Traditional ROI: 3.92%
209 Amethyst Way Seneca, SC Lake Keowee Waterfront Perfection - Renovated Retreat with Private Dock & Shoreline Deck: ...	5 beds \| 4 baths \| N/A	$2,195,000	Airbnb cash on cash: -1.05% Traditional cash on cash: 0.03% Airbnb Rental Income: $1731 Traditional Rental Income: $3445 Airbnb ROI: -1.05% Traditional ROI: 0.03%
403 S Walnut Street Seneca, SC CHARMING! Take a look at this downtown bungalow in Seneca SC! Home has over 1300 square fe...	3 beds \| 2 baths \| 1,346 sq.ft.	$215,000	Airbnb cash on cash: 3.53% Traditional cash on cash: 7.38% Airbnb Rental Income: $1513 Traditional Rental Income: $1855 Airbnb ROI: 3.53% Traditional ROI: 7.38%
12010 W Camelia Lane Seneca, SC This home sits on a quiet culd-a-sac, perfectly Situated home in the heart of Seneca, nest...	4 beds \| 3 baths \| N/A	$400,000	Airbnb cash on cash: 1.59% Traditional cash on cash: 5.33% Airbnb Rental Income: $1713 Traditional Rental Income: $2640 Airbnb ROI: 1.59% Traditional ROI: 5.33%
5060 Keowee School Road Seneca, SC Completely remodeled in beautiful location close to Lake Keowee access! This charming 2-be...	2 beds \| 1 baths \| N/A	$246,500	Airbnb cash on cash: 2.47% Traditional cash on cash: 3.07% Airbnb Rental Income: $1466 Traditional Rental Income: $1173 Airbnb ROI: 2.47% Traditional ROI: 3.07%
127 Oak Ridge Circle Seneca, SC Beautifully updated and move-in ready! This 3-bedroom, 1.5-bath ranch in Seneca sits on a ...	3 beds \| 2 baths \| 1,008 sq.ft.	$199,990	Airbnb cash on cash: 3.59% Traditional cash on cash: 6.04% Airbnb Rental Income: $1513 Traditional Rental Income: $1538 Airbnb ROI: 3.59% Traditional ROI: 6.04%
1104 Little River View Drive Seneca, SC A beautiful crafted custom Craftsman-style home, nestled in the prestigious gated communit...	4 beds \| 3 baths \| 1,824 sq.ft.	$697,900	Airbnb cash on cash: -0.17% Traditional cash on cash: 1.44% Airbnb Rental Income: $1713 Traditional Rental Income: $2282 Airbnb ROI: -0.17% Traditional ROI: 1.44%
318 Weeping Willow Drive Seneca, SC Single-level living marries an exceptional outdoor setting in this charming three-bedroom,...	3 beds \| 3 baths \| 1,250 sq.ft.	$265,000	Airbnb cash on cash: 2.35% Traditional cash on cash: 6.49% Airbnb Rental Income: $1513 Traditional Rental Income: $2108 Airbnb ROI: 2.35% Traditional ROI: 6.49%
116 Elliott Drive Seneca, SC Welcome home to this 3 bedroom, 2 bath retreat nestled on 0.65 acres. A spacious 2-car det...	3 beds \| 2 baths \| N/A	$340,000	Airbnb cash on cash: 1.5% Traditional cash on cash: 4.06% Airbnb Rental Income: $1513 Traditional Rental Income: $1891 Airbnb ROI: 1.5% Traditional ROI: 4.06%
217 Singing Pines Road Seneca, SC 2022 built 3 bed 2 bath FULLY FURNISHED Craftsman home with 1546 square feet of living spa...	3 beds \| 2 baths \| 1,546 sq.ft.	$339,000	Airbnb cash on cash: 1.51% Traditional cash on cash: 3.52% Airbnb Rental Income: $1513 Traditional Rental Income: $1713 Airbnb ROI: 1.51% Traditional ROI: 3.52%
213 Singing Pines Road Seneca, SC Fully furnished 3 bed 2 bath built in 2022. Seller is currently running as an Airbnb. Over...	3 beds \| 2 baths \| 1,546 sq.ft.	$329,000	Airbnb cash on cash: 1.6% Traditional cash on cash: 3.67% Airbnb Rental Income: $1513 Traditional Rental Income: $1713 Airbnb ROI: 1.6% Traditional ROI: 3.67%
2024 Corinth Drive Seneca, SC Great 4 bedroom 2 full bath ranch home is centrally located between Seneca and Clemson. It...	4 beds \| 2 baths \| 1,630 sq.ft.	$259,000	Airbnb cash on cash: 3.43% Traditional cash on cash: 6.5% Airbnb Rental Income: $1713 Traditional Rental Income: $1989 Airbnb ROI: 3.43% Traditional ROI: 6.5%
302 Meadowlark Lane Seneca, SC Donald Gardner beautiful custom style home on 2.96 acres and just a short drive to Lake Ke...	4 beds \| 4 baths \| 2,960 sq.ft.	$599,000	Airbnb cash on cash: -0.22% Traditional cash on cash: 3.42% Airbnb Rental Income: $1713 Traditional Rental Income: $3272 Airbnb ROI: -0.22% Traditional ROI: 3.42%
401 Promontory Ridge Seneca, SC Welcome to 401 Promontory Ridge, where Southern charm meets modern living, wrapped up in a...	4 beds \| 3 baths \| 2,748 sq.ft.	$759,000	Airbnb cash on cash: -0.02% Traditional cash on cash: 1.79% Airbnb Rental Income: $1713 Traditional Rental Income: $2518 Airbnb ROI: -0.02% Traditional ROI: 1.79%
505 Dalton Road Seneca, SC Discover this meticulous 3 bedroom, 2.5 bath Cape Cod home in Seneca, offering the perfect...	3 beds \| 3 baths \| 2,400 sq.ft.	$529,900	Airbnb cash on cash: 0.86% Traditional cash on cash: 2.36% Airbnb Rental Income: $1513 Traditional Rental Income: $1816 Airbnb ROI: 0.86% Traditional ROI: 2.36%
305 Wynswept Point Seneca, SC When the view matters more than anything else this is the home for you!With more than a mi...	4 beds \| 4 baths \| N/A	$2,450,000	Airbnb cash on cash: -0.68% Traditional cash on cash: -0.3% Airbnb Rental Income: $1713 Traditional Rental Income: $2119 Airbnb ROI: -0.68% Traditional ROI: -0.3%
103 Fair Haven Court Seneca, SC Welcome to 103 Fair Haven Ct in Seneca, SCâa private lakefront retreat nestled on nearly...	5 beds \| 4 baths \| N/A	$775,000	Airbnb cash on cash: 0.04% Traditional cash on cash: 2.71% Airbnb Rental Income: $1731 Traditional Rental Income: $3181 Airbnb ROI: 0.04% Traditional ROI: 2.71%
1044 Fairfield Drive Seneca, SC Welcome to Fairfield Place, a Great Southern Homes community boasting larger floorplans wi...	3 beds \| 3 baths \| 2,100 sq.ft.	$332,000	Airbnb cash on cash: 1.37% Traditional cash on cash: 4.77% Airbnb Rental Income: $1513 Traditional Rental Income: $2132 Airbnb ROI: 1.37% Traditional ROI: 4.77%
506 Inlet Drive Seneca, SC Discover your perfect Lake Keowee getaway! This charming waterfront cottage comes with its...	4 beds \| 3 baths \| N/A	$1,650,000	Airbnb cash on cash: -0.52% Traditional cash on cash: 0.16% Airbnb Rental Income: $1713 Traditional Rental Income: $2268 Airbnb ROI: -0.52% Traditional ROI: 0.16%
213 Terrace View Way Seneca, SC At over 3400 square feet, this beautiful 4 bed, 3.5 bath home with a large recreation room...	4 beds \| 4 baths \| N/A	$515,000	Airbnb cash on cash: 0.73% Traditional cash on cash: 4.62% Airbnb Rental Income: $1713 Traditional Rental Income: $3110 Airbnb ROI: 0.73% Traditional ROI: 4.62%
270 Meridian Way Seneca, SC Welcome to Preston Ridge. Oconee County's most desirable townhome development. Maintenance...	3 beds \| 2 baths \| N/A	$369,000	Airbnb cash on cash: 0.67% Traditional cash on cash: 2.86% Airbnb Rental Income: $1513 Traditional Rental Income: $1830 Airbnb ROI: 0.67% Traditional ROI: 2.86%
260 Meridian Way Seneca, SC Welcome to Preston Ridge. Oconee County's most desirable townhome development. Maintenance...	3 beds \| 2 baths \| N/A	$369,000	Airbnb cash on cash: 0.67% Traditional cash on cash: 2.86% Airbnb Rental Income: $1513 Traditional Rental Income: $1830 Airbnb ROI: 0.67% Traditional ROI: 2.86%
14001 Rhine Court Seneca, SC This gem of a home is nestled into the lovely neighborhood of Saxony Forest. This communit...	5 beds \| 4 baths \| 2,600 sq.ft.	$549,000	Airbnb cash on cash: 1.07% Traditional cash on cash: 5.2% Airbnb Rental Income: $1731 Traditional Rental Income: $3368 Airbnb ROI: 1.07% Traditional ROI: 5.2%
003 Harbin Acres Road Seneca, SC This Beautiful 3 Bedroom 2 Full Bath sits on more than 1 1/2 acres, and is an Amazing Oppo...	3 beds \| 2 baths \| N/A	$289,900	Airbnb cash on cash: 2.02% Traditional cash on cash: 5.26% Airbnb Rental Income: $1513 Traditional Rental Income: $1958 Airbnb ROI: 2.02% Traditional ROI: 5.26%
101 Lakeview Drive Seneca, SC BRICK RANCH on a beautiful corner lot in the city limits of Seneca. Older home that has be...	3 beds \| 2 baths \| 1,958 sq.ft.	$299,900	Airbnb cash on cash: 2.25% Traditional cash on cash: 4.94% Airbnb Rental Income: $1513 Traditional Rental Income: $1832 Airbnb ROI: 2.25% Traditional ROI: 4.94%
726 Bellview Way Seneca, SC Great townhome with three bedrooms and two and half baths. Great rental history. All new a...	3 beds \| 3 baths \| N/A	$198,700	Airbnb cash on cash: 3.42% Traditional cash on cash: 6.56% Airbnb Rental Income: $1513 Traditional Rental Income: $1663 Airbnb ROI: 3.42% Traditional ROI: 6.56%
303 Meadow Drive Seneca, SC A hard to find property in today's market within minutes to Clemson or Seneca SC. Home was...	3 beds \| 2 baths \| 1,171 sq.ft.	$275,000	Airbnb cash on cash: 2.62% Traditional cash on cash: 5.34% Airbnb Rental Income: $1513 Traditional Rental Income: $1778 Airbnb ROI: 2.62% Traditional ROI: 5.34%
307 Hunter Street Seneca, SC New Construction! Located in the heart of downtown Seneca, SC, this beautiful residence fe...	3 beds \| 2 baths \| 992 sq.ft.	$194,900	Airbnb cash on cash: 3.72% Traditional cash on cash: 7.91% Airbnb Rental Income: $1513 Traditional Rental Income: $1849 Airbnb ROI: 3.72% Traditional ROI: 7.91%
931 Harts Cove Way, Seneca, SC 29678 Seneca, SC Come tour the condo that offers a lot of possibilities. This condo has shuttle transportat...	3 beds \| 3 baths \| 1,231 sq.ft.	$255,000	Airbnb cash on cash: 2.39% Traditional cash on cash: 5.43% Airbnb Rental Income: $1513 Traditional Rental Income: $1803 Airbnb ROI: 2.39% Traditional ROI: 5.43%
528 Rosedale Way Seneca, SC Welcome to 528 Rosedale Way, where luxury and comfort blend seamlessly in this stunning ne...	3 beds \| 4 baths \| 2,635 sq.ft.	$799,900	Airbnb cash on cash: -0.77% Traditional cash on cash: 1.68% Airbnb Rental Income: $1513 Traditional Rental Income: $2899 Airbnb ROI: -0.77% Traditional ROI: 1.68%
121 Sunset Bay Boulevard Seneca, SC Welcome to 121 Sunset Bay Blvd, where comfort meets convenience in this beautiful 4-bedroo...	4 beds \| 3 baths \| N/A	$569,900	Airbnb cash on cash: 0.58% Traditional cash on cash: 2.95% Airbnb Rental Income: $1713 Traditional Rental Income: $2500 Airbnb ROI: 0.58% Traditional ROI: 2.95%

Real Estate investment in Seneca, SC

There are 103 properties for sale in the city of Seneca . The median list price in Seneca is $340,000 and the average price per square foot is $158. In December 2025, the average monthly cash on cash return in Seneca is 5.00%. The average monthly rental income in Seneca is $2,071.

Seneca, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 103 investment properties available for sale in Seneca.

In 2025, the best neighborhood to buy investment property is Seneca.

The ROI for Long-Term is higher than the Short-Term in Seneca with average rental income of $2,071.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, SC

1006 Kaye Street

Seneca, SC

3 beds | 3 baths | 1,889 sq.ft.

$299,000

Airbnb cash on cash: 2.35%

Traditional cash on cash: 6.54%

Airbnb Rental Income: $1513

Traditional Rental Income: $2251

Airbnb ROI: 2.35%

Traditional ROI: 6.54%

4306 Ashford Bluff Drive

Seneca, SC

3 beds | 3 baths | 3,144 sq.ft.

$590,000

Airbnb cash on cash: 0.21%

Traditional cash on cash: 2.58%

Airbnb Rental Income: $1513

Traditional Rental Income: $2377

Airbnb ROI: 0.21%

Traditional ROI: 2.58%

256 Terrace View Way

Seneca, SC

3 beds | 2 baths | 1,927 sq.ft.

$340,000

Airbnb cash on cash: 1.82%

Traditional cash on cash: 5.66%

Airbnb Rental Income: $1513

Traditional Rental Income: $2300

Airbnb ROI: 1.82%

Traditional ROI: 5.66%

208 Terrace View Way

Seneca, SC

3 beds | 2 baths | N/A

$340,000

Airbnb cash on cash: 1.73%

Traditional cash on cash: 4.68%

Airbnb Rental Income: $1513

Traditional Rental Income: $2015

Airbnb ROI: 1.73%

Traditional ROI: 4.68%

216 Riverbank Court

Seneca, SC

3 beds | 3 baths | 3,300 sq.ft.

$419,900

Airbnb cash on cash: 0.9%

Traditional cash on cash: 3.61%

Airbnb Rental Income: $1513

Traditional Rental Income: $2136

Airbnb ROI: 0.9%

Traditional ROI: 3.61%

1298 Carradine Road

Seneca, SC

3 beds | 3 baths | 2,146 sq.ft.

$405,000

Airbnb cash on cash: 1.16%

Traditional cash on cash: 3.92%

Airbnb Rental Income: $1513

Traditional Rental Income: $2118

Airbnb ROI: 1.16%

Traditional ROI: 3.92%

209 Amethyst Way

Seneca, SC

5 beds | 4 baths | N/A

$2,195,000

Airbnb cash on cash: -1.05%

Traditional cash on cash: 0.03%

Airbnb Rental Income: $1731

Traditional Rental Income: $3445

Airbnb ROI: -1.05%

Traditional ROI: 0.03%

403 S Walnut Street

Seneca, SC

3 beds | 2 baths | 1,346 sq.ft.

$215,000

Airbnb cash on cash: 3.53%

Traditional cash on cash: 7.38%

Airbnb Rental Income: $1513

Traditional Rental Income: $1855

Airbnb ROI: 3.53%