Real Estate Investment Properties for Sale in Seneca, SC

Looking for investment property in Seneca, SC with high ROI ?

Explore a variety of short-term homes & houses in Seneca, SC. Invest wisely with VRBO & Seneca, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4306 Ashford Bluff Drive Seneca, SC MOVE IN READY. Welcome to 4306 Ashford Bluff Dr., Seneca, SC. A beautiful home nestled in ...	3 beds \| 3 baths \| 3,144 sq.ft.	$575,000	Airbnb cash on cash: 0.26% Traditional cash on cash: 2.69% Airbnb Rental Income: $1513 Traditional Rental Income: $2377 Airbnb ROI: 0.26% Traditional ROI: 2.69%
256 Terrace View Way Seneca, SC The spacious home offers three large bedrooms and two full baths on the main level, as wel...	3 beds \| 2 baths \| 1,927 sq.ft.	$340,000	Airbnb cash on cash: 1.82% Traditional cash on cash: 5.66% Airbnb Rental Income: $1513 Traditional Rental Income: $2300 Airbnb ROI: 1.82% Traditional ROI: 5.66%
208 Terrace View Way Seneca, SC Looking for a move-in-ready 3-bedroom home in Shadowood subdivision near Clemson Universit...	3 beds \| 2 baths \| N/A	$340,000	Airbnb cash on cash: 1.73% Traditional cash on cash: 4.68% Airbnb Rental Income: $1513 Traditional Rental Income: $2015 Airbnb ROI: 1.73% Traditional ROI: 4.68%
218 Thomas Heights Circle Seneca, SC Move-in ready and close to it all, this 3BR/1.5BA brick ranch offers easy living just minu...	3 beds \| 2 baths \| 962 sq.ft.	$228,500	Airbnb cash on cash: 3.07% Traditional cash on cash: 4.97% Airbnb Rental Income: $1513 Traditional Rental Income: $1482 Airbnb ROI: 3.07% Traditional ROI: 4.97%
216 Riverbank Court Seneca, SC Don't miss this rare opportunity to own a beautifully crafted, Troyer built home in the de...	3 beds \| 3 baths \| 3,300 sq.ft.	$419,900	Airbnb cash on cash: 0.9% Traditional cash on cash: 3.61% Airbnb Rental Income: $1513 Traditional Rental Income: $2136 Airbnb ROI: 0.9% Traditional ROI: 3.61%
29 Humbert Street Seneca, SC Full of character and move-in ready, this 2-bedroom, 1-bath home offers comfort, simplicit...	2 beds \| 1 baths \| N/A	$105,000	Airbnb cash on cash: 7.6% Traditional cash on cash: 9.57% Airbnb Rental Income: $1466 Traditional Rental Income: $1234 Airbnb ROI: 7.6% Traditional ROI: 9.57%
140 Westlake Drive Seneca, SC Welcome to the desirable Waterford Pointe community on Lake Keowee. This stunning communit...	4 beds \| 3 baths \| 3,095 sq.ft.	$1,200,000	Airbnb cash on cash: -0.22% Traditional cash on cash: 1.06% Airbnb Rental Income: $1713 Traditional Rental Income: $2666 Airbnb ROI: -0.22% Traditional ROI: 1.06%
715 Bellview Way Seneca, SC End-unit townhouse offering 3 bedrooms and 2.5 baths, conveniently located minutes from do...	3 beds \| 3 baths \| N/A	$194,900	Airbnb cash on cash: 3.67% Traditional cash on cash: 8.91% Airbnb Rental Income: $1513 Traditional Rental Income: $2041 Airbnb ROI: 3.67% Traditional ROI: 8.91%
1298 Carradine Road Seneca, SC LAKE COMMUNITY with LAKE ACCESS less than 5 miles to Clemson campus and Death Valley! 1298...	3 beds \| 3 baths \| 2,146 sq.ft.	$394,000	Airbnb cash on cash: 1.22% Traditional cash on cash: 4.06% Airbnb Rental Income: $1513 Traditional Rental Income: $2118 Airbnb ROI: 1.22% Traditional ROI: 4.06%
851 Louie Lane Seneca, SC Newer roof, windows, and appliances! Welcome to this charming, single-level residence in t...	4 beds \| 2 baths \| 1,282 sq.ft.	$275,000	Airbnb cash on cash: 2.85% Traditional cash on cash: 4.42% Airbnb Rental Income: $1713 Traditional Rental Income: $1646 Airbnb ROI: 2.85% Traditional ROI: 4.42%
129 Shadowood Court Seneca, SC Fantastic Seneca location- Shadowood Subdivision just off of Hwy 123 with easy access to C...	3 beds \| 2 baths \| 1,900 sq.ft.	$330,000	Airbnb cash on cash: 1.48% Traditional cash on cash: 4.51% Airbnb Rental Income: $1513 Traditional Rental Income: $2011 Airbnb ROI: 1.48% Traditional ROI: 4.51%
123 New Heritage Trail Seneca, SC Imagine coming home to this stunning brick beauty that's basically begging to become your ...	4 beds \| 4 baths \| 3,272 sq.ft.	$925,000	Airbnb cash on cash: -0.24% Traditional cash on cash: 2.09% Airbnb Rental Income: $1713 Traditional Rental Income: $3238 Airbnb ROI: -0.24% Traditional ROI: 2.09%
209 Amethyst Way Seneca, SC Lake Keowee Waterfront Perfection - Renovated Retreat with Private Dock & Shoreline Deck: ...	5 beds \| 4 baths \| N/A	$2,195,000	Airbnb cash on cash: -1.05% Traditional cash on cash: 0.03% Airbnb Rental Income: $1731 Traditional Rental Income: $3445 Airbnb ROI: -1.05% Traditional ROI: 0.03%
403 S Walnut Street Seneca, SC CHARMING! Take a look at this downtown bungalow in Seneca SC! Home has over 1300 square fe...	3 beds \| 2 baths \| 1,346 sq.ft.	$215,000	Airbnb cash on cash: 3.53% Traditional cash on cash: 7.38% Airbnb Rental Income: $1513 Traditional Rental Income: $1855 Airbnb ROI: 3.53% Traditional ROI: 7.38%
731 Harts Cove Way Seneca, SC Welcome to 731 Harts Cove Way, this is a well maintained and thoughtfully cared for 3 bed,...	3 beds \| 3 baths \| N/A	$265,000	Airbnb cash on cash: 1.09% Traditional cash on cash: 4.75% Airbnb Rental Income: $1513 Traditional Rental Income: $1986 Airbnb ROI: 1.09% Traditional ROI: 4.75%
12010 W Camelia Lane Seneca, SC This home sits on a quiet culd-a-sac, perfectly Situated home in the heart of Seneca, nest...	4 beds \| 3 baths \| N/A	$400,000	Airbnb cash on cash: 1.59% Traditional cash on cash: 5.33% Airbnb Rental Income: $1713 Traditional Rental Income: $2640 Airbnb ROI: 1.59% Traditional ROI: 5.33%
5060 Keowee School Road Seneca, SC Completely remodeled in beautiful location close to Lake Keowee access! This charming 2-be...	2 beds \| 1 baths \| N/A	$234,500	Airbnb cash on cash: 2.67% Traditional cash on cash: 3.3% Airbnb Rental Income: $1466 Traditional Rental Income: $1173 Airbnb ROI: 2.67% Traditional ROI: 3.3%
122 Fair Haven Court Seneca, SC Discover Fair Haven Farms, a truly rare approximately 4-acre lakefront sanctuary on the sh...	4 beds \| 4 baths \| 4,150 sq.ft.	$1,459,000	Airbnb cash on cash: -0.41% Traditional cash on cash: 1.13% Airbnb Rental Income: $1713 Traditional Rental Income: $3336 Airbnb ROI: -0.41% Traditional ROI: 1.13%
1104 Little River View Drive Seneca, SC This Craftsman-style home is nestled on a 1.66 acre interior lot in the prestigious gated ...	5 beds \| 3 baths \| N/A	$697,900	Airbnb cash on cash: -0.14% Traditional cash on cash: 1.44% Airbnb Rental Income: $1731 Traditional Rental Income: $2282 Airbnb ROI: -0.14% Traditional ROI: 1.44%
214 Fisherman Lane Seneca, SC Lakeside living with views and room to grow. 214 Fisherman Lane is a must-see lakeside pro...	2 beds \| 3 baths \| 2,526 sq.ft.	$715,000	Airbnb cash on cash: -0.01% Traditional cash on cash: 1.7% Airbnb Rental Income: $1466 Traditional Rental Income: $2172 Airbnb ROI: -0.01% Traditional ROI: 1.7%
302 Meadowlark Lane Seneca, SC Donald Gardner beautiful custom style home on 2.96 acres and just a short drive to Lake Ke...	4 beds \| 4 baths \| 2,960 sq.ft.	$599,000	Airbnb cash on cash: -0.22% Traditional cash on cash: 3.42% Airbnb Rental Income: $1713 Traditional Rental Income: $3272 Airbnb ROI: -0.22% Traditional ROI: 3.42%
401 Promontory Ridge Seneca, SC Welcome to 401 Promontory Ridge, where Southern charm meets modern living, wrapped up in a...	4 beds \| 3 baths \| 2,748 sq.ft.	$759,000	Airbnb cash on cash: -0.02% Traditional cash on cash: 1.79% Airbnb Rental Income: $1713 Traditional Rental Income: $2518 Airbnb ROI: -0.02% Traditional ROI: 1.79%
305 Wynswept Point Seneca, SC When the view matters more than anything else this is the home for you!With more than a mi...	4 beds \| 4 baths \| N/A	$2,450,000	Airbnb cash on cash: -0.68% Traditional cash on cash: -0.3% Airbnb Rental Income: $1713 Traditional Rental Income: $2119 Airbnb ROI: -0.68% Traditional ROI: -0.3%
103 Fair Haven Court Seneca, SC Welcome to 103 Fair Haven Ct in Seneca, SC. This 5-bedroom, 3.5-bath home has over 3,600 s...	5 beds \| 4 baths \| N/A	$750,000	Airbnb cash on cash: 0.09% Traditional cash on cash: 2.85% Airbnb Rental Income: $1731 Traditional Rental Income: $3181 Airbnb ROI: 0.09% Traditional ROI: 2.85%
1044 Fairfield Drive Seneca, SC Welcome to Fairfield Place, a Great Southern Homes community boasting larger floorplans wi...	3 beds \| 3 baths \| 2,100 sq.ft.	$332,000	Airbnb cash on cash: 1.37% Traditional cash on cash: 4.77% Airbnb Rental Income: $1513 Traditional Rental Income: $2132 Airbnb ROI: 1.37% Traditional ROI: 4.77%
506 Inlet Drive Seneca, SC Discover your perfect Lake Keowee getaway! This charming waterfront cottage comes with its...	4 beds \| 3 baths \| N/A	$1,650,000	Airbnb cash on cash: -0.52% Traditional cash on cash: 0.16% Airbnb Rental Income: $1713 Traditional Rental Income: $2268 Airbnb ROI: -0.52% Traditional ROI: 0.16%
213 Terrace View Way Seneca, SC At over 3400 square feet, this beautiful 4 bed, 3.5 bath home with a large recreation room...	4 beds \| 4 baths \| N/A	$500,000	Airbnb cash on cash: 0.8% Traditional cash on cash: 4.8% Airbnb Rental Income: $1713 Traditional Rental Income: $3110 Airbnb ROI: 0.8% Traditional ROI: 4.8%
1218 Friendship Road Seneca, SC With 24.21 acres and over 500 feet of road frontage on Friendship rd and another 60 feet o...	3 beds \| 1 baths \| 1,343 sq.ft.	$670,000	Airbnb cash on cash: 0% Traditional cash on cash: 0.21% Airbnb Rental Income: $1513 Traditional Rental Income: $1202 Airbnb ROI: 0% Traditional ROI: 0.21%
270 Meridian Way Seneca, SC Welcome to Preston Ridge. Oconee County's most desirable townhome development. Maintenance...	3 beds \| 2 baths \| N/A	$369,000	Airbnb cash on cash: 0.67% Traditional cash on cash: 2.86% Airbnb Rental Income: $1513 Traditional Rental Income: $1830 Airbnb ROI: 0.67% Traditional ROI: 2.86%
14001 Rhine Court Seneca, SC This gem of a home is nestled at the top of the hill in the lovely neighborhood of Saxony ...	5 beds \| 4 baths \| 3,600 sq.ft.	$549,000	Airbnb cash on cash: 1.07% Traditional cash on cash: 5.2% Airbnb Rental Income: $1731 Traditional Rental Income: $3368 Airbnb ROI: 1.07% Traditional ROI: 5.2%
1555 Fort Hill Drive Seneca, SC Spacious, Private, and Just Minutes from Clemson - A Hidden Gem with Quality Construction....	3 beds \| 3 baths \| N/A	$334,900	Airbnb cash on cash: 1.9% Traditional cash on cash: 5.03% Airbnb Rental Income: $1513 Traditional Rental Income: $2057 Airbnb ROI: 1.9% Traditional ROI: 5.03%
613 Aqua View Drive Seneca, SC An architectural masterpieces set on 2.69 private acres, in the sought after lakefront com...	4 beds \| 3 baths \| 2,530 sq.ft.	$929,999	Airbnb cash on cash: 0.01% Traditional cash on cash: 1.85% Airbnb Rental Income: $1713 Traditional Rental Income: $2829 Airbnb ROI: 0.01% Traditional ROI: 1.85%
150 Cedar Hill Drive Seneca, SC Great home built by a builder for a builder! Tucked away and private. This brick Ranch sty...	2 beds \| 2 baths \| 1,334 sq.ft.	$375,000	Airbnb cash on cash: 1.19% Traditional cash on cash: 2.87% Airbnb Rental Income: $1466 Traditional Rental Income: $1623 Airbnb ROI: 1.19% Traditional ROI: 2.87%
726 Bellview Way Seneca, SC Great townhome with three bedrooms and two and half baths. Great rental history. All new a...	3 beds \| 3 baths \| N/A	$195,500	Airbnb cash on cash: 3.49% Traditional cash on cash: 6.68% Airbnb Rental Income: $1513 Traditional Rental Income: $1663 Airbnb ROI: 3.49% Traditional ROI: 6.68%
303 Meadow Drive Seneca, SC A hard to find property in today's market within minutes to Clemson or Seneca SC. Home was...	3 beds \| 2 baths \| 1,171 sq.ft.	$275,000	Airbnb cash on cash: 2.62% Traditional cash on cash: 5.34% Airbnb Rental Income: $1513 Traditional Rental Income: $1778 Airbnb ROI: 2.62% Traditional ROI: 5.34%
307 Hunter Street Seneca, SC New Construction! Located in the heart of downtown Seneca, SC, this beautiful residence fe...	3 beds \| 2 baths \| 992 sq.ft.	$189,900	Airbnb cash on cash: 3.86% Traditional cash on cash: 8.16% Airbnb Rental Income: $1513 Traditional Rental Income: $1849 Airbnb ROI: 3.86% Traditional ROI: 8.16%
121 Sunset Bay Boulevard Seneca, SC Welcome to 121 Sunset Bay Blvd, where comfort meets convenience in this beautiful 4-bedroo...	4 beds \| 3 baths \| N/A	$569,900	Airbnb cash on cash: 0.58% Traditional cash on cash: 2.95% Airbnb Rental Income: $1713 Traditional Rental Income: $2500 Airbnb ROI: 0.58% Traditional ROI: 2.95%
536 E South 5th Street Seneca, SC Back on the market at no fault of the seller! Welcome to 536 E South 5th Street - a beauti...	2 beds \| 2 baths \| 864 sq.ft.	$199,900	Airbnb cash on cash: 3.81% Traditional cash on cash: 8.12% Airbnb Rental Income: $1466 Traditional Rental Income: $1850 Airbnb ROI: 3.81% Traditional ROI: 8.12%
221 Lakeside Drive Seneca, SC Renovated lake-house will make the perfect full time home, weekend getaway or short-term R...	3 beds \| 3 baths \| N/A	$1,199,000	Airbnb cash on cash: -0.69% Traditional cash on cash: 0.72% Airbnb Rental Income: $1513 Traditional Rental Income: $2640 Airbnb ROI: -0.69% Traditional ROI: 0.72%

Real Estate investment in Seneca, SC

There are 99 properties for sale in the city of Seneca . The median list price in Seneca is $394,000 and the average price per square foot is $171. In January 2026, the average monthly cash on cash return in Seneca is 3.00%. The average monthly rental income in Seneca is $2,006.

Seneca, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 99 investment properties available for sale in Seneca.

In 2026, the best neighborhood to buy investment property is Seneca.

The ROI for Long-Term is higher than the Short-Term in Seneca with average rental income of $2,006.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, SC

4306 Ashford Bluff Drive

Seneca, SC

3 beds | 3 baths | 3,144 sq.ft.

$575,000

Airbnb cash on cash: 0.26%

Traditional cash on cash: 2.69%

Airbnb Rental Income: $1513

Traditional Rental Income: $2377

Airbnb ROI: 0.26%

Traditional ROI: 2.69%

256 Terrace View Way

Seneca, SC

3 beds | 2 baths | 1,927 sq.ft.

$340,000

Airbnb cash on cash: 1.82%

Traditional cash on cash: 5.66%

Airbnb Rental Income: $1513

Traditional Rental Income: $2300

Airbnb ROI: 1.82%

Traditional ROI: 5.66%

208 Terrace View Way

Seneca, SC

3 beds | 2 baths | N/A

$340,000

Airbnb cash on cash: 1.73%

Traditional cash on cash: 4.68%

Airbnb Rental Income: $1513

Traditional Rental Income: $2015

Airbnb ROI: 1.73%

Traditional ROI: 4.68%

218 Thomas Heights Circle

Seneca, SC

3 beds | 2 baths | 962 sq.ft.

$228,500

Airbnb cash on cash: 3.07%

Traditional cash on cash: 4.97%

Airbnb Rental Income: $1513

Traditional Rental Income: $1482

Airbnb ROI: 3.07%

Traditional ROI: 4.97%

216 Riverbank Court

Seneca, SC

3 beds | 3 baths | 3,300 sq.ft.

$419,900

Airbnb cash on cash: 0.9%

Traditional cash on cash: 3.61%

Airbnb Rental Income: $1513

Traditional Rental Income: $2136

Airbnb ROI: 0.9%

Traditional ROI: 3.61%

29 Humbert Street

Seneca, SC

2 beds | 1 baths | N/A

$105,000

Airbnb cash on cash: 7.6%

Traditional cash on cash: 9.57%

Airbnb Rental Income: $1466

Traditional Rental Income: $1234

Airbnb ROI: 7.6%

Traditional ROI: 9.57%

140 Westlake Drive

Seneca, SC

4 beds | 3 baths | 3,095 sq.ft.

$1,200,000

Airbnb cash on cash: -0.22%

Traditional cash on cash: 1.06%

Airbnb Rental Income: $1713

Traditional Rental Income: $2666

Airbnb ROI: -0.22%

Traditional ROI: 1.06%

715 Bellview Way

Seneca, SC

3 beds | 3 baths | N/A

$194,900

Airbnb cash on cash: 3.67%

Traditional cash on cash: 8.91%

Airbnb Rental Income: $1513

Traditional Rental Income: $2041

Airbnb ROI: 3.67%