Real Estate Investment Properties for Sale in Chamberlain, SD

Looking for investment property in Chamberlain, SD with high ROI ?

Explore a variety of short-term homes & houses in Chamberlain, SD. Invest wisely with VRBO & Chamberlain, SD Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Chamberlain, SD

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
209 S Merrill Chamberlain, SD	4 beds \| 2 baths \| 2,178 sq.ft.	$194,900	Airbnb cash on cash: 7.35% Traditional cash on cash: 11.56% Airbnb Rental Income: $2481 Traditional Rental Income: $2657 Airbnb ROI: 7.35% Traditional ROI: 11.56%
301 S Main Street Chamberlain, SD Beautifully kept and with each room, the 1900's period brings back yesteryear. Solid inte...	3 beds \| N/A baths \| 1,804 sq.ft.	$224,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.62% Airbnb Rental Income: $null Traditional Rental Income: $2122 Airbnb ROI: N/A Traditional ROI: 7.62%
24269 State 50 Hwy Chamberlain, SD Nestled just outside of Chamberlain, this rustic log cabin offers the perfect blend of pea...	3 beds \| 2 baths \| 2,015 sq.ft.	$590,000	Airbnb cash on cash: N/A Traditional cash on cash: 3% Airbnb Rental Income: $null Traditional Rental Income: $2557 Airbnb ROI: N/A Traditional ROI: 3%
300 E Stearns Ave Chamberlain, SD This stunning Tudor-style home stands out with its steep rooflines, brick-and-stucco exter...	3 beds \| 2 baths \| 2,135 sq.ft.	$289,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.21% Airbnb Rental Income: $null Traditional Rental Income: $2570 Airbnb ROI: N/A Traditional ROI: 7.21%
627 Byron Blvd Chamberlain, SD Welcome to this stunning 5-bedroom, 3-bath home located in the desirable Smokey Groves add...	5 beds \| 3 baths \| 2,033 sq.ft.	$439,900	Airbnb cash on cash: 1.97% Traditional cash on cash: 5.12% Airbnb Rental Income: $2360 Traditional Rental Income: $3075 Airbnb ROI: 1.97% Traditional ROI: 5.12%
24889 343rd St Chamberlain, SD Only minutes away from city limits and located immediately off County oil 343rd Ave. At t...	3 beds \| 2 baths \| 1,568 sq.ft.	$388,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.53% Airbnb Rental Income: $null Traditional Rental Income: $2293 Airbnb ROI: N/A Traditional ROI: 4.53%
904 S Sanborn St Chamberlain, SD This house is a beautiful ranch home with a connected two-stall garage. The home was recen...	4 beds \| 2 baths \| 2,820 sq.ft.	$314,900	Airbnb cash on cash: 4.21% Traditional cash on cash: 7.54% Airbnb Rental Income: $2481 Traditional Rental Income: $2865 Airbnb ROI: 4.21% Traditional ROI: 7.54%
208 Lakeview Ave Chamberlain, SD This home offers a very homey feeling with an easy traffic flow from room to room. Three ...	5 beds \| 2 baths \| 2,106 sq.ft.	$369,000	Airbnb cash on cash: 2.74% Traditional cash on cash: 5.5% Airbnb Rental Income: $2360 Traditional Rental Income: $2734 Airbnb ROI: 2.74% Traditional ROI: 5.5%
219 N Grace St Chamberlain, SD Charming 4-Bedroom Home in the Heart of Chamberlain Discover character and potential in th...	4 beds \| 2 baths \| 2,120 sq.ft.	$239,900	Airbnb cash on cash: 5.96% Traditional cash on cash: 9.44% Airbnb Rental Income: $2481 Traditional Rental Income: $2668 Airbnb ROI: 5.96% Traditional ROI: 9.44%

Real Estate investment in Chamberlain, SD

There are 9 properties for sale in the city of Chamberlain . The median list price in Chamberlain is $314,900 and the average price per square foot is $151. In December 2025, the average monthly cash on cash return in Chamberlain is 7.00%. The average monthly rental income in Chamberlain is $2,570.

Chamberlain, SD Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 9 investment properties available for sale in Chamberlain.

In 2025, the best neighborhood to buy investment property is Chamberlain.

The ROI for Long-Term is higher than the Short-Term in Chamberlain with average rental income of $2,570.

Your search for investment property begins and ends here

Investment Property for Sale in Chamberlain, SD

209 S Merrill

Chamberlain, SD

4 beds | 2 baths | 2,178 sq.ft.

$194,900

Airbnb cash on cash: 7.35%

Traditional cash on cash: 11.56%

Airbnb Rental Income: $2481

Traditional Rental Income: $2657

Airbnb ROI: 7.35%

Traditional ROI: 11.56%

301 S Main Street

Chamberlain, SD

3 beds | N/A baths | 1,804 sq.ft.

$224,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.62%

Airbnb Rental Income: $null

Traditional Rental Income: $2122

Airbnb ROI: N/A

Traditional ROI: 7.62%

24269 State 50 Hwy

Chamberlain, SD

3 beds | 2 baths | 2,015 sq.ft.

$590,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3%

Airbnb Rental Income: $null

Traditional Rental Income: $2557

Airbnb ROI: N/A

Traditional ROI: 3%

300 E Stearns Ave

Chamberlain, SD

3 beds | 2 baths | 2,135 sq.ft.

$289,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.21%

Airbnb Rental Income: $null

Traditional Rental Income: $2570

Airbnb ROI: N/A

Traditional ROI: 7.21%

627 Byron Blvd

Chamberlain, SD

5 beds | 3 baths | 2,033 sq.ft.

$439,900

Airbnb cash on cash: 1.97%

Traditional cash on cash: 5.12%

Airbnb Rental Income: $2360

Traditional Rental Income: $3075

Airbnb ROI: 1.97%

Traditional ROI: 5.12%

24889 343rd St

Chamberlain, SD

3 beds | 2 baths | 1,568 sq.ft.

$388,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.53%

Airbnb Rental Income: $null

Traditional Rental Income: $2293

Airbnb ROI: N/A

Traditional ROI: 4.53%

904 S Sanborn St

Chamberlain, SD

4 beds | 2 baths | 2,820 sq.ft.

$314,900

Airbnb cash on cash: 4.21%

Traditional cash on cash: 7.54%

Airbnb Rental Income: $2481

Traditional Rental Income: $2865

Airbnb ROI: 4.21%

Traditional ROI: 7.54%

208 Lakeview Ave

Chamberlain, SD

5 beds | 2 baths | 2,106 sq.ft.

$369,000

Airbnb cash on cash: 2.74%

Traditional cash on cash: 5.5%

Airbnb Rental Income: $2360

Traditional Rental Income: $2734

Airbnb ROI: 2.74%