Real Estate Investment Properties for Sale in Vermillion, SD

Looking for investment property in Vermillion, SD with high ROI ?

Explore a variety of short-term homes & houses in Vermillion, SD. Invest wisely with VRBO & Vermillion, SD Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Vermillion, SD

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1204 Lincoln Vermillion, SD Here is a great opportunity to own and live in a two-story home with an income producing t...	N/A beds \| N/A baths \| 3,090 sq.ft.	$379,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.18% Airbnb Rental Income: $null Traditional Rental Income: $1066 Airbnb ROI: N/A Traditional ROI: 0.18%
2506 E Main St Vermillion, SD Charming Log Cabin Retreat Near Vermillion!! Nestled on nearly a half~acre just outside of...	3 beds \| 2 baths \| 1,647 sq.ft.	$379,499	Airbnb cash on cash: 0.17% Traditional cash on cash: 3.99% Airbnb Rental Income: $1619 Traditional Rental Income: $2518 Airbnb ROI: 0.17% Traditional ROI: 3.99%
103 N Pine Vermillion, SD Fantastic spot near USD Campus, this 4 bedroom, 2 bathroom home features a detached single...	4 beds \| 2 baths \| 1,632 sq.ft.	$209,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.88% Airbnb Rental Income: $null Traditional Rental Income: $1700 Airbnb ROI: N/A Traditional ROI: 5.88%
105/107 Dartmouth Vermillion, SD	N/A beds \| N/A baths \| 1,911 sq.ft.	$245,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.91% Airbnb Rental Income: $null Traditional Rental Income: $1821 Airbnb ROI: N/A Traditional ROI: 4.91%
2410 E Main Vermillion, SD This property boasts numerous features: a triple~car garage, and over 3,000+ square feet o...	4 beds \| 2 baths \| 3,012 sq.ft.	$309,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.59% Airbnb Rental Income: $null Traditional Rental Income: $2856 Airbnb ROI: N/A Traditional ROI: 6.59%
8 N Yale Vermillion, SD Welcome to this charming, renovated 1950's home located on the corner of Main Street and Y...	3 beds \| 2 baths \| 2,034 sq.ft.	$309,000	Airbnb cash on cash: 1.63% Traditional cash on cash: 6.92% Airbnb Rental Income: $1619 Traditional Rental Income: $2698 Airbnb ROI: 1.63% Traditional ROI: 6.92%
121 Kidder Street Vermillion, SD Great investment opportunity on commercial building in downtown Vermillion. 2 long term t...	N/A beds \| N/A baths \| 10,800 sq.ft.	$750,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.3% Airbnb Rental Income: $null Traditional Rental Income: $1747 Airbnb ROI: N/A Traditional ROI: 0.3%
722 E Main Street Vermillion, SD Wonderful starter home located on the corner of Main Street and Plum Street!! This is a f...	4 beds \| 3 baths \| 1,629 sq.ft.	$219,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.54% Airbnb Rental Income: $null Traditional Rental Income: $2521 Airbnb ROI: N/A Traditional ROI: 9.54%
30975 University Road Vermillion, SD This stunning country acreage is everything you have been looking for! Well known by guest...	3 beds \| 2 baths \| 2,088 sq.ft.	$489,900	Airbnb cash on cash: 0.7% Traditional cash on cash: 3.74% Airbnb Rental Income: $1619 Traditional Rental Income: $2556 Airbnb ROI: 0.7% Traditional ROI: 3.74%
46653 Walkers place #14 Vermillion, SD Rare opportunity to own your own home on the Vermillion River, located at Walker Landing.....	3 beds \| 1 baths \| 740 sq.ft.	$179,900	Airbnb cash on cash: 4% Traditional cash on cash: 7.82% Airbnb Rental Income: $1619 Traditional Rental Income: $1815 Airbnb ROI: 4% Traditional ROI: 7.82%
9 N Pine Vermillion, SD Charming single~family home located on the corner of Main Street and Pine Street. Beautif...	5 beds \| 3 baths \| 2,681 sq.ft.	$265,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.9% Airbnb Rental Income: $null Traditional Rental Income: $3448 Airbnb ROI: N/A Traditional ROI: 10.9%
4 W Clark Vermillion, SD Now, here's a great duplex, just 1 block west of the University of South Dakota campus! E...	N/A beds \| N/A baths \| 2,496 sq.ft.	$350,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.9% Airbnb Rental Income: $null Traditional Rental Income: $1878 Airbnb ROI: N/A Traditional ROI: 2.9%
121 S University Vermillion, SD Nestled on a generous .59-acre lot in the heart of Vermillion, this historic home boasts 5...	5 beds \| 3 baths \| 2,700 sq.ft.	$314,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.63% Airbnb Rental Income: $null Traditional Rental Income: $3130 Airbnb ROI: N/A Traditional ROI: 7.63%
46577 Missouri St. #80 Vermillion, SD Discover the perfect getaway along the Vermillion River! This cozy 1-bedroom, 1-bathroom c...	1 beds \| 1 baths \| 729 sq.ft.	$114,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.21% Airbnb Rental Income: $null Traditional Rental Income: $1397 Airbnb ROI: N/A Traditional ROI: 7.21%
803 W Main St. Vermillion, SD This is a great opportunity to own a property located within the city limits, totaling 2.6...	2 beds \| 1 baths \| 1,785 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.77% Airbnb Rental Income: $null Traditional Rental Income: $1759 Airbnb ROI: N/A Traditional ROI: 3.77%
317 Zitkala-Sa Trl. Vermillion, SD Here's a stunning new construction ranch home by AMS Building Systems that you won't want ...	3 beds \| 2 baths \| 1,600 sq.ft.	$399,900	Airbnb cash on cash: 1.67% Traditional cash on cash: 5.28% Airbnb Rental Income: $1619 Traditional Rental Income: $2514 Airbnb ROI: 1.67% Traditional ROI: 5.28%
1220 Zitkala-Sa Trl. Vermillion, SD Step into style and comfort with this stunning, brand-new construction twin home, featurin...	3 beds \| 2 baths \| 1,696 sq.ft.	$359,900	Airbnb cash on cash: 2.07% Traditional cash on cash: 6.32% Airbnb Rental Income: $1619 Traditional Rental Income: $2597 Airbnb ROI: 2.07% Traditional ROI: 6.32%
1222 Zitkala-Sa Trl. Vermillion, SD Step into style and comfort with this stunning, brand-new construction twin home, featurin...	3 beds \| 2 baths \| 1,696 sq.ft.	$359,900	Airbnb cash on cash: 2.07% Traditional cash on cash: 6.32% Airbnb Rental Income: $1619 Traditional Rental Income: $2597 Airbnb ROI: 2.07% Traditional ROI: 6.32%

Real Estate investment in Vermillion, SD

There are 19 properties for sale in the city of Vermillion . The median list price in Vermillion is $304,000 and the average price per square foot is $135. In October 2025, the average monthly cash on cash return in Vermillion is 6.00%. The average monthly rental income in Vermillion is $2,463.

Vermillion, SD Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 19 investment properties available for sale in Vermillion.

In 2025, the best neighborhood to buy investment property is Vermillion.

The ROI for Long-Term is higher than the Short-Term in Vermillion with average rental income of $2,463.

Your search for investment property begins and ends here

Investment Property for Sale in Vermillion, SD

1204 Lincoln

Vermillion, SD

N/A beds | N/A baths | 3,090 sq.ft.

$379,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.18%

Airbnb Rental Income: $null

Traditional Rental Income: $1066

Airbnb ROI: N/A

Traditional ROI: 0.18%

2506 E Main St

Vermillion, SD

3 beds | 2 baths | 1,647 sq.ft.

$379,499

Airbnb cash on cash: 0.17%

Traditional cash on cash: 3.99%

Airbnb Rental Income: $1619

Traditional Rental Income: $2518

Airbnb ROI: 0.17%

Traditional ROI: 3.99%

103 N Pine

Vermillion, SD

4 beds | 2 baths | 1,632 sq.ft.

$209,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.88%

Airbnb Rental Income: $null

Traditional Rental Income: $1700

Airbnb ROI: N/A

Traditional ROI: 5.88%

105/107 Dartmouth

Vermillion, SD

N/A beds | N/A baths | 1,911 sq.ft.

$245,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.91%

Airbnb Rental Income: $null

Traditional Rental Income: $1821

Airbnb ROI: N/A

Traditional ROI: 4.91%

2410 E Main

Vermillion, SD

4 beds | 2 baths | 3,012 sq.ft.

$309,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.59%

Airbnb Rental Income: $null

Traditional Rental Income: $2856

Airbnb ROI: N/A

Traditional ROI: 6.59%

8 N Yale

Vermillion, SD

3 beds | 2 baths | 2,034 sq.ft.

$309,000

Airbnb cash on cash: 1.63%

Traditional cash on cash: 6.92%

Airbnb Rental Income: $1619

Traditional Rental Income: $2698

Airbnb ROI: 1.63%

Traditional ROI: 6.92%

121 Kidder Street

Vermillion, SD

N/A beds | N/A baths | 10,800 sq.ft.

$750,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.3%

Airbnb Rental Income: $null

Traditional Rental Income: $1747

Airbnb ROI: N/A

Traditional ROI: 0.3%

722 E Main Street

Vermillion, SD

4 beds | 3 baths | 1,629 sq.ft.

$219,000

Airbnb cash on cash: N/A

Traditional cash on cash: 9.54%

Airbnb Rental Income: $null

Traditional Rental Income: $2521

Airbnb ROI: N/A