Real Estate Investment Properties for Sale in Vermillion, SD

Looking for investment property in Vermillion, SD with high ROI ?

Explore a variety of short-term homes & houses in Vermillion, SD. Invest wisely with VRBO & Vermillion, SD Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Vermillion, SD

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
218 Center Vermillion, SD Welcome to an excellent opportunity for first-time homebuyers or investors alike!! This ch...	2 beds \| 1 baths \| 736 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.1% Airbnb Rental Income: $null Traditional Rental Income: $1669 Airbnb ROI: N/A Traditional ROI: 8.1%
218 Center St Vermillion, SD Updated and located walking distance to Downtown Vermillion or a few blocks from the Unive...	2 beds \| 1 baths \| 736 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.31% Airbnb Rental Income: $null Traditional Rental Income: $1394 Airbnb ROI: N/A Traditional ROI: 7.31%
216-216 1/2 High Vermillion, SD Lots of potential with this property. its on 2 lots , so there is room to expand if desire...	5 beds \| 3 baths \| 1,676 sq.ft.	$209,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.66% Airbnb Rental Income: $null Traditional Rental Income: $1846 Airbnb ROI: N/A Traditional ROI: 5.66%
216-218 W Cedar Vermillion, SD This up and down duplex is close to downtown, schools and park. Upper unit is a 2 bdrm , 1...	4 beds \| 2 baths \| 1,924 sq.ft.	$169,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.17% Airbnb Rental Income: $null Traditional Rental Income: $1749 Airbnb ROI: N/A Traditional ROI: 7.17%
103 N Pine St Vermillion, SD Fantastic spot near USD Campus, this 4 bedroom, 2 bathroom home features a detached single...	4 beds \| 2 baths \| 1,632 sq.ft.	$209,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.8% Airbnb Rental Income: $null Traditional Rental Income: $1700 Airbnb ROI: N/A Traditional ROI: 5.8%
105/107 Dartmouth St Vermillion, SD	4 beds \| 2 baths \| 1,911 sq.ft.	$235,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.16% Airbnb Rental Income: $null Traditional Rental Income: $1821 Airbnb ROI: N/A Traditional ROI: 5.16%
121 Kidder Street Vermillion, SD Great investment opportunity on commercial building in downtown Vermillion. 2 long term t...	N/A beds \| N/A baths \| 10,800 sq.ft.	$720,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.36% Airbnb Rental Income: $null Traditional Rental Income: $1747 Airbnb ROI: N/A Traditional ROI: 0.36%
310 W Cedar St Vermillion, SD This charming bungalow is ideally situated in a quiet neighborhood, offering a serene livi...	1 beds \| 1 baths \| 860 sq.ft.	$175,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.8% Airbnb Rental Income: $null Traditional Rental Income: $1387 Airbnb ROI: N/A Traditional ROI: 5.8%
46653 Walkers place #14 Vermillion, SD Rare opportunity to own your own home on the Vermillion River, located at Walker Landing.....	3 beds \| 1 baths \| 740 sq.ft.	$179,900	Airbnb cash on cash: 4.03% Traditional cash on cash: 7.82% Airbnb Rental Income: $1626 Traditional Rental Income: $1815 Airbnb ROI: 4.03% Traditional ROI: 7.82%
4 W Clark Vermillion, SD There was no relaxing this past Holiday!! This fantastic duplex had some major upgrades c...	6 beds \| 2 baths \| 2,496 sq.ft.	$279,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.87% Airbnb Rental Income: $null Traditional Rental Income: $1878 Airbnb ROI: N/A Traditional ROI: 3.87%
317 Zitkala-sa Trl Vermillion, SD Here's a stunning new construction ranch home by AMS Building Systems that you won't want ...	3 beds \| 2 baths \| 1,600 sq.ft.	$399,900	Airbnb cash on cash: 1.68% Traditional cash on cash: 5.28% Airbnb Rental Income: $1626 Traditional Rental Income: $2514 Airbnb ROI: 1.68% Traditional ROI: 5.28%
1220 Zitkala-sa Trl Vermillion, SD Step into style and comfort with this stunning, brand-new construction twin home, featurin...	3 beds \| 2 baths \| 1,696 sq.ft.	$359,900	Airbnb cash on cash: 2.09% Traditional cash on cash: 6.32% Airbnb Rental Income: $1626 Traditional Rental Income: $2597 Airbnb ROI: 2.09% Traditional ROI: 6.32%
1222 Zitkala-sa Trl Vermillion, SD Step into style and comfort with this stunning, brand-new construction twin home, featurin...	3 beds \| 2 baths \| 1,696 sq.ft.	$359,900	Airbnb cash on cash: 2.09% Traditional cash on cash: 6.32% Airbnb Rental Income: $1626 Traditional Rental Income: $2597 Airbnb ROI: 2.09% Traditional ROI: 6.32%
2025 Augusta Dr Vermillion, SD A house to "GROW IN", lots of living space. Main floor living room, dining room, kitchen ...	3 beds \| 3 baths \| 2,416 sq.ft.	$429,900	Airbnb cash on cash: -0.39% Traditional cash on cash: 3.7% Airbnb Rental Income: $1626 Traditional Rental Income: $2811 Airbnb ROI: -0.39% Traditional ROI: 3.7%
1556 Crestview Dr Vermillion, SD Welcome to this beautifully updated 5 bedroom, 3.75 bath home, thoughtfully updated from t...	5 beds \| 4 baths \| 3,024 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.55% Airbnb Rental Income: $null Traditional Rental Income: $3625 Airbnb ROI: N/A Traditional ROI: 4.55%
15 E Duke St Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 2 baths \| 2,059 sq.ft.	$389,900	Airbnb cash on cash: 0.64% Traditional cash on cash: 5.43% Airbnb Rental Income: $1626 Traditional Rental Income: $2919 Airbnb ROI: 0.64% Traditional ROI: 5.43%
17 E Duke St Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 2 baths \| 1,990 sq.ft.	$384,900	Airbnb cash on cash: 0.68% Traditional cash on cash: 5.46% Airbnb Rental Income: $1626 Traditional Rental Income: $2893 Airbnb ROI: 0.68% Traditional ROI: 5.46%
19 E Duke St Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 2 baths \| 2,059 sq.ft.	$394,900	Airbnb cash on cash: 0.6% Traditional cash on cash: 5.32% Airbnb Rental Income: $1626 Traditional Rental Income: $2914 Airbnb ROI: 0.6% Traditional ROI: 5.32%
21 E Duke St Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 2 baths \| 1,990 sq.ft.	$384,900	Airbnb cash on cash: 0.68% Traditional cash on cash: 5.46% Airbnb Rental Income: $1626 Traditional Rental Income: $2893 Airbnb ROI: 0.68% Traditional ROI: 5.46%
23 E Duke St Vermillion, SD Welcome to North42! This beautiful townhome is part of Phase 1 of an exciting new developm...	3 beds \| 2 baths \| 2,026 sq.ft.	$389,900	Airbnb cash on cash: 0.64% Traditional cash on cash: 5.41% Airbnb Rental Income: $1626 Traditional Rental Income: $2911 Airbnb ROI: 0.64% Traditional ROI: 5.41%
302 Elm St Vermillion, SD	2 beds \| 1 baths \| 1,162 sq.ft.	$159,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.7% Airbnb Rental Income: $null Traditional Rental Income: $1306 Airbnb ROI: N/A Traditional ROI: 5.7%
46031 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$295,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.15% Airbnb Rental Income: $null Traditional Rental Income: $1049 Airbnb ROI: N/A Traditional ROI: 1.15%
46039 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$269,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.37% Airbnb Rental Income: $null Traditional Rental Income: $769 Airbnb ROI: N/A Traditional ROI: 0.37%
46027 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$284,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.23% Airbnb Rental Income: $null Traditional Rental Income: $769 Airbnb ROI: N/A Traditional ROI: 0.23%
46023 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$279,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.27% Airbnb Rental Income: $null Traditional Rental Income: $769 Airbnb ROI: N/A Traditional ROI: 0.27%
46019 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$269,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.37% Airbnb Rental Income: $null Traditional Rental Income: $769 Airbnb ROI: N/A Traditional ROI: 0.37%
46043 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$272,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.43% Airbnb Rental Income: $null Traditional Rental Income: $1049 Airbnb ROI: N/A Traditional ROI: 1.43%
46047 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$279,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.34% Airbnb Rental Income: $null Traditional Rental Income: $1049 Airbnb ROI: N/A Traditional ROI: 1.34%
46035 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$279,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.34% Airbnb Rental Income: $null Traditional Rental Income: $1049 Airbnb ROI: N/A Traditional ROI: 1.34%
46055 Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| 0 sq.ft.	$315,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.93% Airbnb Rental Income: $null Traditional Rental Income: $1049 Airbnb ROI: N/A Traditional ROI: 0.93%
336 Purdue St St Vermillion, SD	3 beds \| 2 baths \| 1,665 sq.ft.	$450,000	Airbnb cash on cash: 0.25% Traditional cash on cash: 3.16% Airbnb Rental Income: $1626 Traditional Rental Income: $2392 Airbnb ROI: 0.25% Traditional ROI: 3.16%
459th St St Vermillion, SD	N/A beds \| N/A baths \| 1,680 sq.ft.	$869,860	Airbnb cash on cash: N/A Traditional cash on cash: 0.29% Airbnb Rental Income: $null Traditional Rental Income: $2195 Airbnb ROI: N/A Traditional ROI: 0.29%
00000 453rd Vermillion, SD	N/A beds \| N/A baths \| N/A	$150,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.42% Airbnb Rental Income: $null Traditional Rental Income: $769 Airbnb ROI: N/A Traditional ROI: 2.42%
120 Franklin St Vermillion, SD 4 bdrms, 2 full baths ( one is new). Main floor has 2 bedrooms, second floor has 2 more, a...	4 beds \| 2 baths \| 1,488 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.23% Airbnb Rental Income: $null Traditional Rental Income: $2323 Airbnb ROI: N/A Traditional ROI: 10.23%
122 N Yale St Vermillion, SD	5 beds \| 1 baths \| 4,529 sq.ft.	$475,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.73% Airbnb Rental Income: $null Traditional Rental Income: $1886 Airbnb ROI: N/A Traditional ROI: 1.73%
8 Anderson St Vermillion, SD	4 beds \| 2 baths \| 1,920 sq.ft.	$310,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.21% Airbnb Rental Income: $null Traditional Rental Income: $2282 Airbnb ROI: N/A Traditional ROI: 5.21%
TBD 460th Ave. And Daniel Pl Vermillion, SD	N/A beds \| N/A baths \| N/A	$320,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.04% Airbnb Rental Income: $null Traditional Rental Income: $797 Airbnb ROI: N/A Traditional ROI: 0.04%
1804 Augusta Dr Vermillion, SD	5 beds \| 3 baths \| 3,058 sq.ft.	$499,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.62% Airbnb Rental Income: $null Traditional Rental Income: $2856 Airbnb ROI: N/A Traditional ROI: 3.62%
46653 Walkers Place #15 Vermillion, SD Get a head start on enjoying the outdoors on completely custom built and year round home l...	2 beds \| 2 baths \| 900 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.5% Airbnb Rental Income: $null Traditional Rental Income: $1935 Airbnb ROI: N/A Traditional ROI: 8.5%
1826 Constance Dr Vermillion, SD	3 beds \| 2 baths \| 2,660 sq.ft.	$469,000	Airbnb cash on cash: 0.05% Traditional cash on cash: 2.56% Airbnb Rental Income: $1626 Traditional Rental Income: $2318 Airbnb ROI: 0.05% Traditional ROI: 2.56%

Real Estate investment in Vermillion, SD

There are 47 properties for sale in the city of Vermillion . The median list price in Vermillion is $235,000 and the average price per square foot is $144. In March 2026, the average monthly cash on cash return in Vermillion is 6.00%. The average monthly rental income in Vermillion is $1,685.

Vermillion, SD Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 47 investment properties available for sale in Vermillion.

In 2026, the best neighborhood to buy investment property is Vermillion.

The ROI for Long-Term is higher than the Short-Term in Vermillion with average rental income of $1,685.

Your search for investment property begins and ends here

Investment Property for Sale in Vermillion, SD

218 Center

Vermillion, SD

2 beds | 1 baths | 736 sq.ft.

$149,900

Airbnb cash on cash: N/A

Traditional cash on cash: 8.1%

Airbnb Rental Income: $null

Traditional Rental Income: $1669

Airbnb ROI: N/A

Traditional ROI: 8.1%

218 Center St

Vermillion, SD

2 beds | 1 baths | 736 sq.ft.

$149,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.31%

Airbnb Rental Income: $null

Traditional Rental Income: $1394

Airbnb ROI: N/A

Traditional ROI: 7.31%

216-216 1/2 High

Vermillion, SD

5 beds | 3 baths | 1,676 sq.ft.

$209,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.66%

Airbnb Rental Income: $null

Traditional Rental Income: $1846

Airbnb ROI: N/A

Traditional ROI: 5.66%

216-218 W Cedar

Vermillion, SD

4 beds | 2 baths | 1,924 sq.ft.

$169,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.17%

Airbnb Rental Income: $null

Traditional Rental Income: $1749

Airbnb ROI: N/A

Traditional ROI: 7.17%

103 N Pine St

Vermillion, SD

4 beds | 2 baths | 1,632 sq.ft.

$209,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.8%

Airbnb Rental Income: $null

Traditional Rental Income: $1700

Airbnb ROI: N/A

Traditional ROI: 5.8%

105/107 Dartmouth St

Vermillion, SD

4 beds | 2 baths | 1,911 sq.ft.

$235,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.16%

Airbnb Rental Income: $null

Traditional Rental Income: $1821

Airbnb ROI: N/A

Traditional ROI: 5.16%

121 Kidder Street

Vermillion, SD

N/A beds | N/A baths | 10,800 sq.ft.

$720,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.36%

Airbnb Rental Income: $null

Traditional Rental Income: $1747

Airbnb ROI: N/A

Traditional ROI: 0.36%

310 W Cedar St

Vermillion, SD

1 beds | 1 baths | 860 sq.ft.

$175,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.8%

Airbnb Rental Income: $null

Traditional Rental Income: $1387

Airbnb ROI: N/A