Real Estate Investment Properties for Sale in Vermillion, SD

Looking for investment property in Vermillion, SD with high ROI ?

Explore a variety of short-term homes & houses in Vermillion, SD. Invest wisely with VRBO & Vermillion, SD Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Vermillion, SD

separator

PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
218 Center Vermillion, SD Welcome to an excellent opportunity for first-time homebuyers or investors alike! This cha...	2 beds \| 1 baths \| 736 sq.ft.	$149,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.1% Airbnb Rental Income: $null Traditional Rental Income: $1669 Airbnb ROI: N/A Traditional ROI: 8.1%
1810 Vonnie Vermillion, SD Start the new year off in this four bedroom, three bathroom home located in the northwest ...	4 beds \| 3 baths \| 2,076 sq.ft.	$329,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.25% Airbnb Rental Income: $null Traditional Rental Income: $2901 Airbnb ROI: N/A Traditional ROI: 6.25%
111 Church Vermillion, SD Charming, historic home in the heart of downtown Vermillion!! This unique 3~bedroom, 2~bat...	3 beds \| 2 baths \| 1,674 sq.ft.	$239,900	Airbnb cash on cash: 2.82% Traditional cash on cash: 6.07% Airbnb Rental Income: $1626 Traditional Rental Income: $1904 Airbnb ROI: 2.82% Traditional ROI: 6.07%
105/107 Dartmouth Vermillion, SD	N/A beds \| N/A baths \| 1,911 sq.ft.	$235,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.16% Airbnb Rental Income: $null Traditional Rental Income: $1821 Airbnb ROI: N/A Traditional ROI: 5.16%
2410 E Main Vermillion, SD This property boasts numerous features: a triple-car garage, and over 3,000+ square feet o...	4 beds \| 2 baths \| 3,012 sq.ft.	$295,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.67% Airbnb Rental Income: $null Traditional Rental Income: $2856 Airbnb ROI: N/A Traditional ROI: 6.67%
8 N Yale Vermillion, SD Welcome to this charming, renovated 1950's home located on the corner of Main Street and Y...	3 beds \| 2 baths \| 2,034 sq.ft.	$309,000	Airbnb cash on cash: 1.65% Traditional cash on cash: 6.92% Airbnb Rental Income: $1626 Traditional Rental Income: $2698 Airbnb ROI: 1.65% Traditional ROI: 6.92%
722 E Main Street Vermillion, SD Wonderful starter home located on the corner of Main Street and Plum Street!! This is a f...	4 beds \| 3 baths \| 1,629 sq.ft.	$212,500	Airbnb cash on cash: N/A Traditional cash on cash: 9.85% Airbnb Rental Income: $null Traditional Rental Income: $2521 Airbnb ROI: N/A Traditional ROI: 9.85%
46653 Walkers place #14 Vermillion, SD Rare opportunity to own your own home on the Vermillion River, located at Walker Landing.....	3 beds \| 1 baths \| 740 sq.ft.	$179,900	Airbnb cash on cash: 4.03% Traditional cash on cash: 7.82% Airbnb Rental Income: $1626 Traditional Rental Income: $1815 Airbnb ROI: 4.03% Traditional ROI: 7.82%
9 N Pine Vermillion, SD Charming single-family home located on the corner of Main Street and Pine Street. Beautif...	5 beds \| 3 baths \| 2,681 sq.ft.	$265,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.9% Airbnb Rental Income: $null Traditional Rental Income: $3448 Airbnb ROI: N/A Traditional ROI: 10.9%
4 W Clark Vermillion, SD There was no relaxing this past Holiday!! This fantastic duplex had some major upgrades c...	N/A beds \| N/A baths \| 2,496 sq.ft.	$350,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.9% Airbnb Rental Income: $null Traditional Rental Income: $1878 Airbnb ROI: N/A Traditional ROI: 2.9%
121 S University Vermillion, SD Nestled on a generous .59-acre lot in the heart of Vermillion, this historic home boasts 5...	5 beds \| 3 baths \| 2,700 sq.ft.	$314,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.63% Airbnb Rental Income: $null Traditional Rental Income: $3130 Airbnb ROI: N/A Traditional ROI: 7.63%
317 Zitkala-Sa Trl. Vermillion, SD Here's a stunning new construction ranch home by AMS Building Systems that you won't want ...	3 beds \| 2 baths \| 1,600 sq.ft.	$399,900	Airbnb cash on cash: 1.68% Traditional cash on cash: 5.28% Airbnb Rental Income: $1626 Traditional Rental Income: $2514 Airbnb ROI: 1.68% Traditional ROI: 5.28%
1220 Zitkala-Sa Trl. Vermillion, SD Step into style and comfort with this stunning, brand~new construction twin home, featurin...	3 beds \| 2 baths \| 1,696 sq.ft.	$359,900	Airbnb cash on cash: 2.09% Traditional cash on cash: 6.32% Airbnb Rental Income: $1626 Traditional Rental Income: $2597 Airbnb ROI: 2.09% Traditional ROI: 6.32%
1222 Zitkala-Sa Trl. Vermillion, SD Step into style and comfort with this stunning, brand-new construction twin home, featurin...	3 beds \| 2 baths \| 1,696 sq.ft.	$359,900	Airbnb cash on cash: 2.09% Traditional cash on cash: 6.32% Airbnb Rental Income: $1626 Traditional Rental Income: $2597 Airbnb ROI: 2.09% Traditional ROI: 6.32%
2025 Augusta Dr Vermillion, SD A house to "GROW IN", lots of living space. Main floor living room, dining room, kitchen ...	3 beds \| 3 baths \| 2,416 sq.ft.	$444,900	Airbnb cash on cash: -0.28% Traditional cash on cash: 3.67% Airbnb Rental Income: $1626 Traditional Rental Income: $2811 Airbnb ROI: -0.28% Traditional ROI: 3.67%
1556 Crestview Dr. Vermillion, SD Welcome to this beautifully updated 5 bedroom, 3.75 bath home, thoughtfully updated from t...	5 beds \| 4 baths \| 3,024 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.55% Airbnb Rental Income: $null Traditional Rental Income: $3625 Airbnb ROI: N/A Traditional ROI: 4.55%
31802 458th Ave. Vermillion, SD This acreage is conveniently located a short drive off Timber Road, is easily accessible t...	5 beds \| 2 baths \| 2,386 sq.ft.	$329,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.47% Airbnb Rental Income: $null Traditional Rental Income: $2787 Airbnb ROI: N/A Traditional ROI: 6.47%
15 E Duke St. Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 3 baths \| 2,059 sq.ft.	$389,900	Airbnb cash on cash: 0.64% Traditional cash on cash: 5.43% Airbnb Rental Income: $1626 Traditional Rental Income: $2919 Airbnb ROI: 0.64% Traditional ROI: 5.43%
17 E Duke St. Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 3 baths \| 1,990 sq.ft.	$384,900	Airbnb cash on cash: 0.68% Traditional cash on cash: 5.46% Airbnb Rental Income: $1626 Traditional Rental Income: $2893 Airbnb ROI: 0.68% Traditional ROI: 5.46%
19 E Duke St. Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 3 baths \| 2,059 sq.ft.	$394,900	Airbnb cash on cash: 0.6% Traditional cash on cash: 5.32% Airbnb Rental Income: $1626 Traditional Rental Income: $2914 Airbnb ROI: 0.6% Traditional ROI: 5.32%
21 E Duke St. Vermillion, SD Welcome to North42! This beautiful townhome is part of Phase 1 of an exciting new developm...	3 beds \| 3 baths \| 1,990 sq.ft.	$384,900	Airbnb cash on cash: 0.68% Traditional cash on cash: 5.46% Airbnb Rental Income: $1626 Traditional Rental Income: $2893 Airbnb ROI: 0.68% Traditional ROI: 5.46%
23 E Duke St. Vermillion, SD Welcome to North42!! This beautiful townhome is part of Phase 1 of an exciting new develop...	3 beds \| 3 baths \| 2,026 sq.ft.	$389,900	Airbnb cash on cash: 0.64% Traditional cash on cash: 5.41% Airbnb Rental Income: $1626 Traditional Rental Income: $2911 Airbnb ROI: 0.64% Traditional ROI: 5.41%
302 S Plum Vermillion, SD This property presents a compelling investment opportunity as a side-by-side duplex with a...	N/A beds \| N/A baths \| 3,424 sq.ft.	$259,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.49% Airbnb Rental Income: $null Traditional Rental Income: $1654 Airbnb ROI: N/A Traditional ROI: 3.49%
1205 Rockwell Vermillion, SD To be Built, Triplex Townhouse â Customize It Your Way! Brand-new construction with qual...	3 beds \| 2 baths \| 1,672 sq.ft.	$344,500	Airbnb cash on cash: 2.14% Traditional cash on cash: 6.28% Airbnb Rental Income: $1626 Traditional Rental Income: $2504 Airbnb ROI: 2.14% Traditional ROI: 6.28%
120 Franklin Vermillion, SD 4 bdrms, 2 full baths ( one is new). Main floor has 2 bedrooms, second floor has 2 more, a...	4 beds \| 2 baths \| 1,488 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.23% Airbnb Rental Income: $null Traditional Rental Income: $2323 Airbnb ROI: N/A Traditional ROI: 10.23%
18 Walker Vermillion, SD This inviting ranch~style home features four bedrooms and two bathrooms, offering ample sp...	4 beds \| 2 baths \| 2,112 sq.ft.	$285,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.22% Airbnb Rental Income: $null Traditional Rental Income: $2609 Airbnb ROI: N/A Traditional ROI: 7.22%

Real Estate investment in Vermillion, SD

There are 26 properties for sale in the city of Vermillion . The median list price in Vermillion is $329,450 and the average price per square foot is $171. In January 2026, the average monthly cash on cash return in Vermillion is 6.00%. The average monthly rental income in Vermillion is $2,654.

Vermillion, SD Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 26 investment properties available for sale in Vermillion.

In 2026, the best neighborhood to buy investment property is Vermillion.

The ROI for Long-Term is higher than the Short-Term in Vermillion with average rental income of $2,654.

Your search for investment property begins and ends here

Investment Property for Sale in Vermillion, SD

218 Center

Vermillion, SD

2 beds | 1 baths | 736 sq.ft.

$149,900

Airbnb cash on cash: N/A

Traditional cash on cash: 8.1%

Airbnb Rental Income: $null

Traditional Rental Income: $1669

Airbnb ROI: N/A

Traditional ROI: 8.1%

1810 Vonnie

Vermillion, SD

4 beds | 3 baths | 2,076 sq.ft.

$329,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.25%

Airbnb Rental Income: $null

Traditional Rental Income: $2901

Airbnb ROI: N/A

Traditional ROI: 6.25%

111 Church

Vermillion, SD

3 beds | 2 baths | 1,674 sq.ft.

$239,900

Airbnb cash on cash: 2.82%

Traditional cash on cash: 6.07%

Airbnb Rental Income: $1626

Traditional Rental Income: $1904

Airbnb ROI: 2.82%

Traditional ROI: 6.07%

105/107 Dartmouth

Vermillion, SD

N/A beds | N/A baths | 1,911 sq.ft.

$235,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.16%

Airbnb Rental Income: $null

Traditional Rental Income: $1821

Airbnb ROI: N/A

Traditional ROI: 5.16%

2410 E Main

Vermillion, SD

4 beds | 2 baths | 3,012 sq.ft.

$295,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.67%

Airbnb Rental Income: $null

Traditional Rental Income: $2856

Airbnb ROI: N/A

Traditional ROI: 6.67%

8 N Yale

Vermillion, SD

3 beds | 2 baths | 2,034 sq.ft.

$309,000

Airbnb cash on cash: 1.65%

Traditional cash on cash: 6.92%

Airbnb Rental Income: $1626

Traditional Rental Income: $2698

Airbnb ROI: 1.65%

Traditional ROI: 6.92%

722 E Main Street

Vermillion, SD

4 beds | 3 baths | 1,629 sq.ft.

$212,500

Airbnb cash on cash: N/A

Traditional cash on cash: 9.85%

Airbnb Rental Income: $null

Traditional Rental Income: $2521

Airbnb ROI: N/A

Traditional ROI: 9.85%

46653 Walkers place #14

Vermillion, SD

3 beds | 1 baths | 740 sq.ft.

$179,900

Airbnb cash on cash: 4.03%

Traditional cash on cash: 7.82%

Airbnb Rental Income: $1626

Traditional Rental Income: $1815

Airbnb ROI: 4.03%