Real Estate Investment Properties for Sale in Brookline, MO

Looking for investment property in Brookline, MO with high ROI ?

Explore a variety of short-term homes & houses in Brookline, MO. Invest wisely with VRBO & Brookline, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Brookline, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2665 W Old Limey Road Brookline, MO Welcome to Your Private Missouri Countryside Estate! 2665 W Old Limey Road, Brookline, MOE...	5 beds \| 5 baths \| 3,903 sq.ft.	$898,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.73% Airbnb Rental Income: $null Traditional Rental Income: $3777 Airbnb ROI: N/A Traditional ROI: 2.73%
4074 E Ashwood Court Brookline, MO Introducing a 5-bed, 3-bath home with a walkout basement, making it a versatile haven span...	5 beds \| 3 baths \| 3,053 sq.ft.	$393,995	Airbnb cash on cash: N/A Traditional cash on cash: 6.07% Airbnb Rental Income: $null Traditional Rental Income: $3089 Airbnb ROI: N/A Traditional ROI: 6.07%
1755 N Boxwood Drive Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 2 baths \| 1,428 sq.ft.	$261,995	Airbnb cash on cash: 1.99% Traditional cash on cash: 10.41% Airbnb Rental Income: $1335 Traditional Rental Income: $3006 Airbnb ROI: 1.99% Traditional ROI: 10.41%
1763 N Boxwood Drive Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$302,995	Airbnb cash on cash: 1.53% Traditional cash on cash: 7.28% Airbnb Rental Income: $1328 Traditional Rental Income: $2559 Airbnb ROI: 1.53% Traditional ROI: 7.28%
1722 N Hawthorne Place Brookline, MO The Aspen floor plan offers four spacious bedrooms and a world of flexibility to fit your ...	4 beds \| 3 baths \| 2,120 sq.ft.	$336,995	Airbnb cash on cash: 0.56% Traditional cash on cash: 5.39% Airbnb Rental Income: $1328 Traditional Rental Income: $2449 Airbnb ROI: 0.56% Traditional ROI: 5.39%
1758 N Boxwood Drive Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 3 baths \| 1,951 sq.ft.	$297,995	Airbnb cash on cash: 0.88% Traditional cash on cash: 6.48% Airbnb Rental Income: $1328 Traditional Rental Income: $2490 Airbnb ROI: 0.88% Traditional ROI: 6.48%
1750 N Boxwood Drive Brookline, MO Welcome to The Dayton - a thoughtfully designed two-story home perfect for modern living. ...	4 beds \| 3 baths \| 1,746 sq.ft.	$286,995	Airbnb cash on cash: 0.99% Traditional cash on cash: 6.24% Airbnb Rental Income: $1328 Traditional Rental Income: $2338 Airbnb ROI: 0.99% Traditional ROI: 6.24%
1742 N Boxwood Drive Brookline, MO This stunning 3-bedroom, 2-bathroom home spanning 1,550 square feet features an open conce...	3 beds \| 2 baths \| 1,520 sq.ft.	$274,995	Airbnb cash on cash: 1.87% Traditional cash on cash: 7% Airbnb Rental Income: $1335 Traditional Rental Income: $2254 Airbnb ROI: 1.87% Traditional ROI: 7%
5218 S Morgan Avenue Brookline, MO This spacious 3-4 bedroom, 2-bathroom home offers 1,950 square feet of smart, stylish livi...	3 beds \| 2 baths \| 1,977 sq.ft.	$389,595	Airbnb cash on cash: 0.48% Traditional cash on cash: 4.34% Airbnb Rental Income: $1335 Traditional Rental Income: $2335 Airbnb ROI: 0.48% Traditional ROI: 4.34%
1754 N Poplar Way Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 3 baths \| 1,951 sq.ft.	$304,365	Airbnb cash on cash: 0.81% Traditional cash on cash: 6.37% Airbnb Rental Income: $1328 Traditional Rental Income: $2511 Airbnb ROI: 0.81% Traditional ROI: 6.37%
5230 S Morgan Avenue Brookline, MO This floor plan is a 3 bedroom, 2 bathroom 1750 square feet home featuring 10-foot ceiling...	3 beds \| 2 baths \| 1,752 sq.ft.	$356,668	Airbnb cash on cash: 0.62% Traditional cash on cash: 4.53% Airbnb Rental Income: $1335 Traditional Rental Income: $2234 Airbnb ROI: 0.62% Traditional ROI: 4.53%
5224 S Morgan Avenue Brookline, MO This 1950 square foot 4 bedroom, 2 bathroom home features a spacious and open floor plan. ...	4 beds \| 2 baths \| 1,950 sq.ft.	$387,839	Airbnb cash on cash: 0.47% Traditional cash on cash: 4.44% Airbnb Rental Income: $1328 Traditional Rental Income: $2363 Airbnb ROI: 0.47% Traditional ROI: 4.44%
1739 N Knollwood Avenue Brookline, MO Introducing a 5-bed, 3-bath home with a walkout basement, making it a versatile haven span...	5 beds \| 3 baths \| 3,053 sq.ft.	$397,315	Airbnb cash on cash: N/A Traditional cash on cash: 5.8% Airbnb Rental Income: $null Traditional Rental Income: $3015 Airbnb ROI: N/A Traditional ROI: 5.8%
1710 N Boxwood Drive Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$309,570	Airbnb cash on cash: 0.93% Traditional cash on cash: 7.44% Airbnb Rental Income: $1328 Traditional Rental Income: $2812 Airbnb ROI: 0.93% Traditional ROI: 7.44%
1718 N Boxwood Drive Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 3 baths \| 1,428 sq.ft.	$270,390	Airbnb cash on cash: 1.23% Traditional cash on cash: 6.6% Airbnb Rental Income: $1335 Traditional Rental Income: $2294 Airbnb ROI: 1.23% Traditional ROI: 6.6%
1726 N Boxwood Drive Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$310,995	Airbnb cash on cash: 0.92% Traditional cash on cash: 7.33% Airbnb Rental Income: $1328 Traditional Rental Income: $2793 Airbnb ROI: 0.92% Traditional ROI: 7.33%
5242 S Morgan Avenue Brookline, MO	4 beds \| 2 baths \| 1,950 sq.ft.	$385,289	Airbnb cash on cash: 0.49% Traditional cash on cash: 4.41% Airbnb Rental Income: $1328 Traditional Rental Income: $2335 Airbnb ROI: 0.49% Traditional ROI: 4.41%
5877 S Farm Road 115 Brookline, MO Welcome to 5877 South Farm Road 115--your ideal country retreat! This charming home offers...	3 beds \| 1 baths \| 1,176 sq.ft.	$229,900	Airbnb cash on cash: 2.22% Traditional cash on cash: 6.1% Airbnb Rental Income: $1335 Traditional Rental Income: $1767 Airbnb ROI: 2.22% Traditional ROI: 6.1%
6070 S Farm Rd 131 Brookline, MO 6070 Farm Rd 131, Brookline, MO -- offering over 1,400 sqft of living space, this 2 bedroo...	2 beds \| 2 baths \| 1,442 sq.ft.	$250,000	Airbnb cash on cash: -0.1% Traditional cash on cash: 7.25% Airbnb Rental Income: $753 Traditional Rental Income: $2175 Airbnb ROI: -0.1% Traditional ROI: 7.25%
1746 N Poplar Way Brookline, MO The Manhattan design is a study in versatility. For the cook who wants to remain connected...	4 beds \| 3 baths \| 2,059 sq.ft.	$327,017	Airbnb cash on cash: 0.57% Traditional cash on cash: 5.99% Airbnb Rental Income: $1328 Traditional Rental Income: $2583 Airbnb ROI: 0.57% Traditional ROI: 5.99%
1702 N Boxwood Drive Brookline, MO Welcome to The Edgewood, a beautifully designed four-bedroom, 2.5-bath home that offers mo...	4 beds \| 3 baths \| 1,951 sq.ft.	$324,188	Airbnb cash on cash: 1.08% Traditional cash on cash: 6.3% Airbnb Rental Income: $1328 Traditional Rental Income: $2509 Airbnb ROI: 1.08% Traditional ROI: 6.3%
1730 N Poplar Way Brookline, MO Discover the Oakwood floor plan--a spacious two-story, 3-bedroom, 2-bath home thoughtfully...	3 beds \| 2 baths \| 1,428 sq.ft.	$259,995	Airbnb cash on cash: 1.43% Traditional cash on cash: 6.01% Airbnb Rental Income: $1335 Traditional Rental Income: $2048 Airbnb ROI: 1.43% Traditional ROI: 6.01%

Real Estate investment in Brookline, MO

There are 22 properties for sale in the city of Brookline . The median list price in Brookline is $1,725,000 and the average price per square foot is $505. In May 2026, the average monthly cash on cash return in Brookline is 6.00%. The average monthly rental income in Brookline is $2,360.

Brookline, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 22 investment properties available for sale in Brookline.

In 2026, the best neighborhood to buy investment property is Brookline.

The ROI for Long-Term is higher than the Short-Term in Brookline with average rental income of $2,360.

Your search for investment property begins and ends here

Investment Property for Sale in Brookline, MO

2665 W Old Limey Road

Brookline, MO

5 beds | 5 baths | 3,903 sq.ft.

$898,900

Airbnb cash on cash: N/A

Traditional cash on cash: 2.73%

Airbnb Rental Income: $null

Traditional Rental Income: $3777

Airbnb ROI: N/A

Traditional ROI: 2.73%

4074 E Ashwood Court

Brookline, MO

5 beds | 3 baths | 3,053 sq.ft.

$393,995

Airbnb cash on cash: N/A

Traditional cash on cash: 6.07%

Airbnb Rental Income: $null

Traditional Rental Income: $3089

Airbnb ROI: N/A

Traditional ROI: 6.07%

1755 N Boxwood Drive

Brookline, MO

3 beds | 2 baths | 1,428 sq.ft.

$261,995

Airbnb cash on cash: 1.99%

Traditional cash on cash: 10.41%

Airbnb Rental Income: $1335

Traditional Rental Income: $3006

Airbnb ROI: 1.99%

Traditional ROI: 10.41%

1763 N Boxwood Drive

Brookline, MO

4 beds | 3 baths | 2,059 sq.ft.

$302,995

Airbnb cash on cash: 1.53%

Traditional cash on cash: 7.28%

Airbnb Rental Income: $1328

Traditional Rental Income: $2559

Airbnb ROI: 1.53%

Traditional ROI: 7.28%

1722 N Hawthorne Place

Brookline, MO

4 beds | 3 baths | 2,120 sq.ft.

$336,995

Airbnb cash on cash: 0.56%

Traditional cash on cash: 5.39%

Airbnb Rental Income: $1328

Traditional Rental Income: $2449

Airbnb ROI: 0.56%

Traditional ROI: 5.39%

1758 N Boxwood Drive

Brookline, MO

4 beds | 3 baths | 1,951 sq.ft.

$297,995

Airbnb cash on cash: 0.88%

Traditional cash on cash: 6.48%

Airbnb Rental Income: $1328

Traditional Rental Income: $2490

Airbnb ROI: 0.88%

Traditional ROI: 6.48%

1750 N Boxwood Drive

Brookline, MO

4 beds | 3 baths | 1,746 sq.ft.

$286,995

Airbnb cash on cash: 0.99%

Traditional cash on cash: 6.24%

Airbnb Rental Income: $1328

Traditional Rental Income: $2338

Airbnb ROI: 0.99%

Traditional ROI: 6.24%

1742 N Boxwood Drive

Brookline, MO

3 beds | 2 baths | 1,520 sq.ft.

$274,995

Airbnb cash on cash: 1.87%

Traditional cash on cash: 7%

Airbnb Rental Income: $1335

Traditional Rental Income: $2254

Airbnb ROI: 1.87%