Real Estate Investment Properties for Sale in Clayton, MO

Looking for investment property in Clayton, MO with high ROI ?

Explore a variety of short-term homes & houses in Clayton, MO. Invest wisely with VRBO & Clayton, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Clayton, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
710 S Hanley Rd #10A Clayton, MO Ideally located in the well-managed Whitehall building, this elegant and spacious condo of...	3 beds \| 3 baths \| 2,766 sq.ft.	$849,500	Airbnb cash on cash: -3.04% Traditional cash on cash: -1.42% Airbnb Rental Income: $2283 Traditional Rental Income: $2996 Airbnb ROI: -3.04% Traditional ROI: -1.42%
710 S Hanley Rd #10B Clayton, MO Welcome to The Whitehall, one of Claytonâs premier high-rise condominium communities and...	2 beds \| 2 baths \| 1,697 sq.ft.	$499,900	Airbnb cash on cash: -3.55% Traditional cash on cash: -1.06% Airbnb Rental Income: $1309 Traditional Rental Income: $2067 Airbnb ROI: -3.55% Traditional ROI: -1.06%
7545 Wellington Way #1A Clayton, MO Welcome to this beautifully updated condo in the heart of Clayton, set in a well-maintaine...	2 beds \| 2 baths \| 1,417 sq.ft.	$365,000	Airbnb cash on cash: -0.95% Traditional cash on cash: 2.11% Airbnb Rental Income: $1309 Traditional Rental Income: $1953 Airbnb ROI: -0.95% Traditional ROI: 2.11%
923 S Hanley Rd #A Clayton, MO Location, Location, Location! Enjoy walking to shops and restaurants as well as all the e...	1 beds \| 1 baths \| 767 sq.ft.	$146,000	Airbnb cash on cash: -2.01% Traditional cash on cash: 0.32% Airbnb Rental Income: $1000 Traditional Rental Income: $970 Airbnb ROI: -2.01% Traditional ROI: 0.32%
7564 Wydown Blvd #1B Clayton, MO Luxurious 1st floor condo in a supreme Clayton location w/2 Bd 2 full Bth! Light-filled op...	2 beds \| 2 baths \| 1,432 sq.ft.	$440,000	Airbnb cash on cash: -1.44% Traditional cash on cash: 0.39% Airbnb Rental Income: $1309 Traditional Rental Income: $1657 Airbnb ROI: -1.44% Traditional ROI: 0.39%
7520 Oxford Dr #2W Clayton, MO Enjoy easy living in this elegant 2-bedroom, 2 bath, second floor condo with an abundance ...	2 beds \| 2 baths \| 1,612 sq.ft.	$417,900	Airbnb cash on cash: -0.84% Traditional cash on cash: 1.37% Airbnb Rental Income: $1309 Traditional Rental Income: $1769 Airbnb ROI: -0.84% Traditional ROI: 1.37%
900 S Hanley Rd #11B Clayton, MO Discover effortless condo living in this inviting 1-bedroom residence, conveniently locate...	1 beds \| 1 baths \| 1,110 sq.ft.	$139,900	Airbnb cash on cash: -9.36% Traditional cash on cash: -4.75% Airbnb Rental Income: $1000 Traditional Rental Income: $1263 Airbnb ROI: -9.36% Traditional ROI: -4.75%
900 S Hanley Rd #5C Clayton, MO Price improvement for a totally maintenance free, secure living experience in the heart of...	2 beds \| 2 baths \| 1,712 sq.ft.	$234,900	Airbnb cash on cash: -6.89% Traditional cash on cash: -2.07% Airbnb Rental Income: $1309 Traditional Rental Income: $1973 Airbnb ROI: -6.89% Traditional ROI: -2.07%
7570 Byron Pl #3W Clayton, MO PRICE REDUCED- Motivated Seller! Located in the highly sought-after Clayton School Distric...	2 beds \| 1 baths \| 1,074 sq.ft.	$229,900	Airbnb cash on cash: -0.75% Traditional cash on cash: 1.07% Airbnb Rental Income: $1309 Traditional Rental Income: $1298 Airbnb ROI: -0.75% Traditional ROI: 1.07%
816 S Hanley Rd #14B Clayton, MO The one bedroom Clayton condo is located in the prestigious Eight-One-Six South Hanley Bld...	1 beds \| 1 baths \| 1,316 sq.ft.	$399,000	Airbnb cash on cash: -3.81% Traditional cash on cash: -0.04% Airbnb Rental Income: $1000 Traditional Rental Income: $2053 Airbnb ROI: -3.81% Traditional ROI: -0.04%
7324 Northmoor Dr Clayton, MO Welcome.. This home is positively unique in so many great ways! The location itself is f...	4 beds \| 2 baths \| 2,134 sq.ft.	$629,900	Airbnb cash on cash: 0.66% Traditional cash on cash: 1.16% Airbnb Rental Income: $2292 Traditional Rental Income: $2012 Airbnb ROI: 0.66% Traditional ROI: 1.16%
7117 Northmoor Dr Clayton, MO Beautiful 2400sqt+ home in a desirable location with a gorgeous addition you do not want t...	3 beds \| 3 baths \| 2,408 sq.ft.	$699,000	Airbnb cash on cash: 0.48% Traditional cash on cash: 1.84% Airbnb Rental Income: $2283 Traditional Rental Income: $2598 Airbnb ROI: 0.48% Traditional ROI: 1.84%
7544 York Drive #B Clayton, MO An Art Deco exterior leads to a beautiful blend inside of a contemporary & sleek, recently...	2 beds \| 1 baths \| 1,290 sq.ft.	$195,000	Airbnb cash on cash: 0.81% Traditional cash on cash: 0.79% Airbnb Rental Income: $1309 Traditional Rental Income: $899 Airbnb ROI: 0.81% Traditional ROI: 0.79%
150 Carondelet Plz #204 Clayton, MO Luxury Unit with a View- Stunning 2 bedroom + 2.5 bath fully renovated front facing unit w...	2 beds \| 2 baths \| 1,657 sq.ft.	$1,195,000	Airbnb cash on cash: -2.5% Traditional cash on cash: -1.47% Airbnb Rental Income: $1309 Traditional Rental Income: $2041 Airbnb ROI: -2.5% Traditional ROI: -1.47%
900 S Hanley Rd #11D Clayton, MO Don't miss this great opportunity to purchase this updated 2000+ sq. ft, 2bedroom, 2.5 bat...	2 beds \| 2 baths \| 2,025 sq.ft.	$329,000	Airbnb cash on cash: -7.42% Traditional cash on cash: -2.4% Airbnb Rental Income: $1309 Traditional Rental Income: $2455 Airbnb ROI: -7.42% Traditional ROI: -2.4%
132 N Brentwood Blvd Clayton, MO This extraordinary 2024 Slavin Homes built residence offers a lifestyle of refined luxury ...	4 beds \| 4 baths \| 7,383 sq.ft.	$7,495,000	Airbnb cash on cash: -1.15% Traditional cash on cash: -0.45% Airbnb Rental Income: $2292 Traditional Rental Income: $6590 Airbnb ROI: -1.15% Traditional ROI: -0.45%
306 N Central Ave Clayton, MO 306 N Central Ave, Clayton, MO 63105 \| Single Family Residential	4 beds \| 4 baths \| 5,000 sq.ft.	$3,650,000	Airbnb cash on cash: -1.48% Traditional cash on cash: -1.18% Airbnb Rental Income: $2292 Traditional Rental Income: $2738 Airbnb ROI: -1.48% Traditional ROI: -1.18%
7571 Wellington Way #1A Clayton, MO Located in the desirable Moorlands neighborhood of Clayton. This 2bed/2 Full bath condo wa...	2 beds \| 2 baths \| 969 sq.ft.	$229,000	Airbnb cash on cash: 0.32% Traditional cash on cash: 2.87% Airbnb Rental Income: $1309 Traditional Rental Income: $1454 Airbnb ROI: 0.32% Traditional ROI: 2.87%
60 Brighton Way #3S Clayton, MO 60 Brighton Way #3S, Clayton, MO 63105 \| Condo/Coop	3 beds \| 3 baths \| 3,388 sq.ft.	$1,749,900	Airbnb cash on cash: -1.97% Traditional cash on cash: -1.93% Airbnb Rental Income: $2283 Traditional Rental Income: $1779 Airbnb ROI: -1.97% Traditional ROI: -1.93%
710 S Hanley Rd #7B Clayton, MO . Stunning views form the 7th floor of the Whitehall, this northern exposure allows spect...	1 beds \| 1 baths \| 1,276 sq.ft.	$205,000	Airbnb cash on cash: -5.49% Traditional cash on cash: -1.81% Airbnb Rental Income: $1000 Traditional Rental Income: $1360 Airbnb ROI: -5.49% Traditional ROI: -1.81%
900 S Hanley Rd #6C Clayton, MO Welcome to unit 6C in the desirable Hanley Towers, ideally located in the heart of Clayton...	2 beds \| 2 baths \| 1,633 sq.ft.	$289,000	Airbnb cash on cash: -6.19% Traditional cash on cash: -2.36% Airbnb Rental Income: $1309 Traditional Rental Income: $1943 Airbnb ROI: -6.19% Traditional ROI: -2.36%
12 E Brentmoor Park Clayton, MO This architecturally significant Mid-Century Modern masterpiece has been thoughtfully and ...	4 beds \| 7 baths \| 5,900 sq.ft.	$3,950,000	Airbnb cash on cash: -1.26% Traditional cash on cash: 0.15% Airbnb Rental Income: $2292 Traditional Rental Income: $6854 Airbnb ROI: -1.26% Traditional ROI: 0.15%
8125 Halifax Dr Clayton, MO 8125 Halifax Dr, Clayton, MO 63105 \| Single Family Residential	3 beds \| 2 baths \| 2,124 sq.ft.	$449,000	Airbnb cash on cash: 1.89% Traditional cash on cash: 2.33% Airbnb Rental Income: $2283 Traditional Rental Income: $1897 Airbnb ROI: 1.89% Traditional ROI: 2.33%
7532 Cromwell Dr. #2N Clayton, MO Discover the charm of this highly sought after Moorlands condo, a well maintained second f...	2 beds \| 1 baths \| 1,120 sq.ft.	$232,400	Airbnb cash on cash: -0.64% Traditional cash on cash: 1.47% Airbnb Rental Income: $1309 Traditional Rental Income: $1365 Airbnb ROI: -0.64% Traditional ROI: 1.47%
150 Carondelet Plz #1301 Clayton, MO Experience elevated living at the most coveted address in town- The Plaza in Clayton. This...	2 beds \| 2 baths \| 3,744 sq.ft.	$2,395,000	Airbnb cash on cash: -3.26% Traditional cash on cash: -2.64% Airbnb Rental Income: $1309 Traditional Rental Income: $2275 Airbnb ROI: -3.26% Traditional ROI: -2.64%
7012 Forsyth Blvd #3W Clayton, MO Experience comfort and convenience in this charming 2-bedroom, 1-bath condo just steps fro...	2 beds \| 1 baths \| 840 sq.ft.	$195,000	Airbnb cash on cash: -0.19% Traditional cash on cash: 1.18% Airbnb Rental Income: $1309 Traditional Rental Income: $1175 Airbnb ROI: -0.19% Traditional ROI: 1.18%
7542 York Dr #3E Clayton, MO Step into timeless elegance with this fully updated 2-bedroom, 2-bath condo located in a s...	2 beds \| 2 baths \| 1,309 sq.ft.	$324,900	Airbnb cash on cash: -0.89% Traditional cash on cash: 1.89% Airbnb Rental Income: $1309 Traditional Rental Income: $1752 Airbnb ROI: -0.89% Traditional ROI: 1.89%
250 S Brentwood Blvd #1F Clayton, MO Rare opportunity to own an exceptionally spacious and affordable condo offering more than ...	3 beds \| 2 baths \| 2,249 sq.ft.	$325,000	Airbnb cash on cash: -0.8% Traditional cash on cash: 2.79% Airbnb Rental Income: $2283 Traditional Rental Income: $2811 Airbnb ROI: -0.8% Traditional ROI: 2.79%
31 Dartford Ave Clayton, MO 31 Dartford Ave, Clayton, MO 63105 \| Single Family Residential	4 beds \| 2 baths \| 3,619 sq.ft.	$1,150,000	Airbnb cash on cash: -0.46% Traditional cash on cash: -0.33% Airbnb Rental Income: $2292 Traditional Rental Income: $1856 Airbnb ROI: -0.46% Traditional ROI: -0.33%
250 S Brentwood Blvd #1J Clayton, MO 250 S Brentwood Blvd #1J, Clayton, MO 63105 \| Condo/Coop	2 beds \| 2 baths \| 2,082 sq.ft.	$339,900	Airbnb cash on cash: -2.93% Traditional cash on cash: -0.23% Airbnb Rental Income: $1309 Traditional Rental Income: $1763 Airbnb ROI: -2.93% Traditional ROI: -0.23%
61 Topton Way #404 Clayton, MO 61 Topton Way #404, Clayton, MO 63105 \| Condo/Coop	3 beds \| 3 baths \| 2,640 sq.ft.	$1,871,760	Airbnb cash on cash: -1.7% Traditional cash on cash: -1.05% Airbnb Rental Income: $2283 Traditional Rental Income: $2839 Airbnb ROI: -1.7% Traditional ROI: -1.05%
61 Topton Way #301 Clayton, MO 61 Topton Way #301, Clayton, MO 63105 \| Condo/Coop	3 beds \| 2 baths \| 2,464 sq.ft.	$1,722,336	Airbnb cash on cash: -1.68% Traditional cash on cash: -1.26% Airbnb Rental Income: $2283 Traditional Rental Income: $2377 Airbnb ROI: -1.68% Traditional ROI: -1.26%
61 Topton Way #203 Clayton, MO 61 Topton Way #203, Clayton, MO 63105 \| Condo/Coop	2 beds \| 2 baths \| 2,623 sq.ft.	$1,833,477	Airbnb cash on cash: -2.17% Traditional cash on cash: -1.3% Airbnb Rental Income: $1309 Traditional Rental Income: $2394 Airbnb ROI: -2.17% Traditional ROI: -1.3%
7110 Forsyth Blvd Clayton, MO 7110 Forsyth Blvd, Clayton, MO 63105 \| Multi Family	12 beds \| N/A baths \| 5,510 sq.ft.	$1,945,000	Airbnb cash on cash: -1.52% Traditional cash on cash: -1.23% Airbnb Rental Income: $1309 Traditional Rental Income: $1413 Airbnb ROI: -1.52% Traditional ROI: -1.23%
900 S Hanley Rd #3D Clayton, MO Welcome to 900 S. Hanley Road, Unit 3D, ideally located in the heart of Clayton with easy ...	3 beds \| 3 baths \| 2,025 sq.ft.	$299,000	Airbnb cash on cash: -4.71% Traditional cash on cash: -2.32% Airbnb Rental Income: $2283 Traditional Rental Income: $2386 Airbnb ROI: -4.71% Traditional ROI: -2.32%
31 Brighton Way #3 Clayton, MO The entire third floor is yours. This extraordinary 4,000-square-foot residence redefines ...	3 beds \| 3 baths \| 4,087 sq.ft.	$2,500,000	Airbnb cash on cash: -1.71% Traditional cash on cash: -1.69% Airbnb Rental Income: $2283 Traditional Rental Income: $1759 Airbnb ROI: -1.71% Traditional ROI: -1.69%
200 S Brentwood Blvd #13F Clayton, MO Welcome to the 13th floor of the highly sought-after Park Tower, where luxury, privacy, an...	2 beds \| 2 baths \| 1,204 sq.ft.	$225,000	Airbnb cash on cash: -5.48% Traditional cash on cash: -4.26% Airbnb Rental Income: $1309 Traditional Rental Income: $1162 Airbnb ROI: -5.48% Traditional ROI: -4.26%
44 Broadview Dr Clayton, MO 44 Broadview Dr, Clayton, MO 63105 \| Single Family Residential	5 beds \| 4 baths \| 6,006 sq.ft.	$2,580,000	Airbnb cash on cash: -0.76% Traditional cash on cash: -0.53% Airbnb Rental Income: $3810 Traditional Rental Income: $3543 Airbnb ROI: -0.76% Traditional ROI: -0.53%
8015 Davis Dr Clayton, MO	5 beds \| 2 baths \| 2,850 sq.ft.	$1,075,000	Airbnb cash on cash: 0.93% Traditional cash on cash: 0.16% Airbnb Rental Income: $3810 Traditional Rental Income: $2217 Airbnb ROI: 0.93% Traditional ROI: 0.16%
7430 Byron Pl Clayton, MO 7430 Byron Pl, Clayton, MO 63105 \| Single Family Residential	3 beds \| 2 baths \| 2,364 sq.ft.	$799,000	Airbnb cash on cash: 0.21% Traditional cash on cash: 0.58% Airbnb Rental Income: $2283 Traditional Rental Income: $1987 Airbnb ROI: 0.21% Traditional ROI: 0.58%

Clayton, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 61 investment properties available for sale in Clayton.

In 2026, the best neighborhood to buy investment property is Clayton.

The ROI for Short-Term is higher than the Long-Term in Clayton with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Clayton, MO

710 S Hanley Rd #10A

Clayton, MO

3 beds | 3 baths | 2,766 sq.ft.

$849,500

Airbnb cash on cash: -3.04%

Traditional cash on cash: -1.42%

Airbnb Rental Income: $2283

Traditional Rental Income: $2996

Airbnb ROI: -3.04%

Traditional ROI: -1.42%

710 S Hanley Rd #10B

Clayton, MO

2 beds | 2 baths | 1,697 sq.ft.

$499,900

Airbnb cash on cash: -3.55%

Traditional cash on cash: -1.06%

Airbnb Rental Income: $1309

Traditional Rental Income: $2067

Airbnb ROI: -3.55%

Traditional ROI: -1.06%

7545 Wellington Way #1A

Clayton, MO

2 beds | 2 baths | 1,417 sq.ft.

$365,000

Airbnb cash on cash: -0.95%

Traditional cash on cash: 2.11%

Airbnb Rental Income: $1309

Traditional Rental Income: $1953

Airbnb ROI: -0.95%

Traditional ROI: 2.11%

923 S Hanley Rd #A

Clayton, MO

1 beds | 1 baths | 767 sq.ft.

$146,000

Airbnb cash on cash: -2.01%

Traditional cash on cash: 0.32%

Airbnb Rental Income: $1000

Traditional Rental Income: $970

Airbnb ROI: -2.01%

Traditional ROI: 0.32%

7564 Wydown Blvd #1B

Clayton, MO

2 beds | 2 baths | 1,432 sq.ft.

$440,000

Airbnb cash on cash: -1.44%

Traditional cash on cash: 0.39%

Airbnb Rental Income: $1309

Traditional Rental Income: $1657

Airbnb ROI: -1.44%

Traditional ROI: 0.39%

7520 Oxford Dr #2W

Clayton, MO

2 beds | 2 baths | 1,612 sq.ft.

$417,900

Airbnb cash on cash: -0.84%

Traditional cash on cash: 1.37%

Airbnb Rental Income: $1309

Traditional Rental Income: $1769

Airbnb ROI: -0.84%

Traditional ROI: 1.37%

900 S Hanley Rd #11B

Clayton, MO

1 beds | 1 baths | 1,110 sq.ft.

$139,900

Airbnb cash on cash: -9.36%

Traditional cash on cash: -4.75%

Airbnb Rental Income: $1000

Traditional Rental Income: $1263

Airbnb ROI: -9.36%

Traditional ROI: -4.75%

900 S Hanley Rd #5C

Clayton, MO

2 beds | 2 baths | 1,712 sq.ft.

$234,900

Airbnb cash on cash: -6.89%

Traditional cash on cash: -2.07%

Airbnb Rental Income: $1309

Traditional Rental Income: $1973

Airbnb ROI: -6.89%