Real Estate Investment Properties for Sale in Clayton, MO

Looking for investment property in Clayton, MO with high ROI ?

Explore a variety of short-term homes & houses in Clayton, MO. Invest wisely with VRBO & Clayton, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Clayton, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
710 S Hanley Rd #10A Clayton, MO Ideally located in the well-managed Whitehall building, this elegant and spacious condo of...	3 beds \| 3 baths \| 2,766 sq.ft.	$849,500	Airbnb cash on cash: -2.8% Traditional cash on cash: -1.42% Airbnb Rental Income: $2508 Traditional Rental Income: $2996 Airbnb ROI: -2.8% Traditional ROI: -1.42%
710 S Hanley Rd #10B Clayton, MO Welcome to The Whitehall, one of Claytonâs premier high-rise condominium communities and...	2 beds \| 2 baths \| 1,697 sq.ft.	$499,900	Airbnb cash on cash: -3.16% Traditional cash on cash: -1.06% Airbnb Rental Income: $1529 Traditional Rental Income: $2067 Airbnb ROI: -3.16% Traditional ROI: -1.06%
7545 Wellington Way #1A Clayton, MO Welcome to this beautifully updated condo in the heart of Clayton, set in a well-maintaine...	2 beds \| 2 baths \| 1,417 sq.ft.	$365,000	Airbnb cash on cash: -0.42% Traditional cash on cash: 2.11% Airbnb Rental Income: $1529 Traditional Rental Income: $1953 Airbnb ROI: -0.42% Traditional ROI: 2.11%
923 S Hanley Rd #A Clayton, MO Location, Location, Location! Enjoy walking to shops and restaurants as well as all the e...	1 beds \| 1 baths \| 767 sq.ft.	$145,000	Airbnb cash on cash: -1.39% Traditional cash on cash: 0.33% Airbnb Rental Income: $1105 Traditional Rental Income: $970 Airbnb ROI: -1.39% Traditional ROI: 0.33%
8025 Maryland Ave #17C Clayton, MO Welcome home to this exceptional one of a kind Penthouse that is Urban sophistication at i...	3 beds \| 3 baths \| 3,685 sq.ft.	$4,450,000	Airbnb cash on cash: -1.78% Traditional cash on cash: -1.68% Airbnb Rental Income: $2508 Traditional Rental Income: $2298 Airbnb ROI: -1.78% Traditional ROI: -1.68%
7564 Wydown Blvd #1B Clayton, MO Luxurious 1st floor condo in a supreme Clayton location w/2 Bd 2 full Bth! Light-filled op...	2 beds \| 2 baths \| 1,432 sq.ft.	$440,000	Airbnb cash on cash: -1% Traditional cash on cash: 0.39% Airbnb Rental Income: $1529 Traditional Rental Income: $1657 Airbnb ROI: -1% Traditional ROI: 0.39%
7520 Oxford Dr #2W Clayton, MO Enjoy easy living in this elegant 2-bedroom, 2 bath, second floor condo with an abundance ...	2 beds \| 2 baths \| 1,612 sq.ft.	$399,000	Airbnb cash on cash: -0.34% Traditional cash on cash: 1.48% Airbnb Rental Income: $1529 Traditional Rental Income: $1769 Airbnb ROI: -0.34% Traditional ROI: 1.48%
900 S Hanley Rd #11B Clayton, MO Discover effortless condo living in this inviting 1-bedroom residence, conveniently locate...	1 beds \| 1 baths \| 1,110 sq.ft.	$139,900	Airbnb cash on cash: -8.71% Traditional cash on cash: -4.75% Airbnb Rental Income: $1105 Traditional Rental Income: $1263 Airbnb ROI: -8.71% Traditional ROI: -4.75%
925 S Hanley Rd #F Clayton, MO For Sale \| 1,080 Sq Ft \| Art Deco Masterpiece in the Heart of Clayton Own a piece of Clayt...	2 beds \| 1 baths \| 1,080 sq.ft.	$169,900	Airbnb cash on cash: -0.45% Traditional cash on cash: 1.05% Airbnb Rental Income: $1529 Traditional Rental Income: $1328 Airbnb ROI: -0.45% Traditional ROI: 1.05%
8025 Maryland Ave #3F Clayton, MO Sophisticated Urban living in sought after downtown Clayton. Wonderful views welcome you i...	3 beds \| 2 baths \| 1,861 sq.ft.	$998,000	Airbnb cash on cash: -1.65% Traditional cash on cash: -1.2% Airbnb Rental Income: $2508 Traditional Rental Income: $2320 Airbnb ROI: -1.65% Traditional ROI: -1.2%
900 S Hanley Rd #5C Clayton, MO Price improvement for a totally maintenance free, secure living experience in the heart of...	2 beds \| 2 baths \| 1,712 sq.ft.	$234,900	Airbnb cash on cash: -6.07% Traditional cash on cash: -2.07% Airbnb Rental Income: $1529 Traditional Rental Income: $1973 Airbnb ROI: -6.07% Traditional ROI: -2.07%
7570 Byron Pl #3W Clayton, MO PRICE REDUCED- Motivated Seller! Located in the highly sought-after Clayton School Distric...	2 beds \| 1 baths \| 1,074 sq.ft.	$229,900	Airbnb cash on cash: 0.09% Traditional cash on cash: 1.07% Airbnb Rental Income: $1529 Traditional Rental Income: $1298 Airbnb ROI: 0.09% Traditional ROI: 1.07%
816 S Hanley Rd #14B Clayton, MO The one bedroom Clayton condo is located in the prestigious Eight-One-Six South Hanley Bld...	1 beds \| 1 baths \| 1,316 sq.ft.	$399,000	Airbnb cash on cash: -3.57% Traditional cash on cash: -0.04% Airbnb Rental Income: $1105 Traditional Rental Income: $2053 Airbnb ROI: -3.57% Traditional ROI: -0.04%
7035 Forsyth Blvd Clayton, MO Stunning 2-Sty in Forsyth Place neighborhood boasts 3 Bd, 2.5 Bth & 2300+ Sqft including L...	3 beds \| 2 baths \| 1,984 sq.ft.	$719,900	Airbnb cash on cash: 0.85% Traditional cash on cash: 1.04% Airbnb Rental Income: $2508 Traditional Rental Income: $2026 Airbnb ROI: 0.85% Traditional ROI: 1.04%
7324 Northmoor Dr Clayton, MO Welcome.. This home is positively unique in so many great ways! The location itself is f...	4 beds \| 2 baths \| 2,134 sq.ft.	$605,000	Airbnb cash on cash: 1% Traditional cash on cash: 1.24% Airbnb Rental Income: $2473 Traditional Rental Income: $2012 Airbnb ROI: 1% Traditional ROI: 1.24%
7061 Forsyth Blvd Clayton, MO Absolutely stunning 2-story in Forsyth Place neighborhood boasts 4 BR, 2.5 Baths & 3350+ S...	4 beds \| 2 baths \| 3,352 sq.ft.	$955,000	Airbnb cash on cash: 0.21% Traditional cash on cash: 0.62% Airbnb Rental Income: $2473 Traditional Rental Income: $2239 Airbnb ROI: 0.21% Traditional ROI: 0.62%
7536 York Dr #2B Clayton, MO	2 beds \| 1 baths \| 971 sq.ft.	$223,000	Airbnb cash on cash: 0.82% Traditional cash on cash: 1.52% Airbnb Rental Income: $1529 Traditional Rental Income: $1233 Airbnb ROI: 0.82% Traditional ROI: 1.52%
7509 Cromwell Dr Clayton, MO Wonderful 4 bed/2 bath condo in Clayton - must see! Great space and wonderful floor plan w...	4 beds \| 2 baths \| 2,041 sq.ft.	$500,000	Airbnb cash on cash: 0.51% Traditional cash on cash: 1.2% Airbnb Rental Income: $2473 Traditional Rental Income: $2193 Airbnb ROI: 0.51% Traditional ROI: 1.2%
7117 Northmoor Dr Clayton, MO Beautiful 2400sqt+ home in a desirable location with a gorgeous addition you do not want t...	3 beds \| 3 baths \| 2,408 sq.ft.	$699,000	Airbnb cash on cash: 0.77% Traditional cash on cash: 1.84% Airbnb Rental Income: $2508 Traditional Rental Income: $2598 Airbnb ROI: 0.77% Traditional ROI: 1.84%
7544 York Drive #B Clayton, MO An Art Deco exterior leads to a beautiful blend inside of a contemporary & sleek, recently...	2 beds \| 1 baths \| 1,290 sq.ft.	$195,000	Airbnb cash on cash: 1.8% Traditional cash on cash: 0.79% Airbnb Rental Income: $1529 Traditional Rental Income: $899 Airbnb ROI: 1.8% Traditional ROI: 0.79%
8025 Maryland Ave #7A Clayton, MO Sophisticated high-rise living in highly sought after Maryland Walk in the heart of Clayto...	3 beds \| 2 baths \| 1,810 sq.ft.	$1,369,000	Airbnb cash on cash: -1.57% Traditional cash on cash: -0.91% Airbnb Rental Income: $2508 Traditional Rental Income: $2734 Airbnb ROI: -1.57% Traditional ROI: -0.91%
7529 Wellington Way #3 Clayton, MO Imagine living in this light-filled, top-level condo in the heart of the Moorlands. Sophis...	3 beds \| 2 baths \| 1,770 sq.ft.	$395,000	Airbnb cash on cash: 1.27% Traditional cash on cash: 3.98% Airbnb Rental Income: $2508 Traditional Rental Income: $2903 Airbnb ROI: 1.27% Traditional ROI: 3.98%
150 Carondelet Plz #204 Clayton, MO Luxury Unit with a View- Stunning 2 bedroom + 2.5 bath fully renovated front facing unit w...	2 beds \| 2 baths \| 1,657 sq.ft.	$1,195,000	Airbnb cash on cash: -2.34% Traditional cash on cash: -1.47% Airbnb Rental Income: $1529 Traditional Rental Income: $2041 Airbnb ROI: -2.34% Traditional ROI: -1.47%
900 S Hanley Rd #11D Clayton, MO Don't miss this great opportunity to purchase this updated 2000+ sq. ft, 2bedroom, 2.5 bat...	3 beds \| 2 baths \| 2,025 sq.ft.	$329,000	Airbnb cash on cash: -4.19% Traditional cash on cash: -2.4% Airbnb Rental Income: $2508 Traditional Rental Income: $2455 Airbnb ROI: -4.19% Traditional ROI: -2.4%
31 Brighton Way #2B Clayton, MO Welcome home to this stunning two-bedroom, two-and-a-half-bath Clayton Condo which offers ...	2 beds \| 2 baths \| 1,880 sq.ft.	$1,095,000	Airbnb cash on cash: -1.87% Traditional cash on cash: -0.33% Airbnb Rental Income: $1529 Traditional Rental Income: $2649 Airbnb ROI: -1.87% Traditional ROI: -0.33%
132 N Brentwood Blvd Clayton, MO This extraordinary 2024 Slavin Homes built residence offers a lifestyle of refined luxury ...	4 beds \| 4 baths \| 7,383 sq.ft.	$7,495,000	Airbnb cash on cash: -1.13% Traditional cash on cash: -0.45% Airbnb Rental Income: $2473 Traditional Rental Income: $6590 Airbnb ROI: -1.13% Traditional ROI: -0.45%
306 N Central Ave Clayton, MO 306 N Central Ave, Clayton, MO 63105 \| Single Family Residential	4 beds \| 4 baths \| 5,000 sq.ft.	$3,650,000	Airbnb cash on cash: -1.44% Traditional cash on cash: -1.18% Airbnb Rental Income: $2473 Traditional Rental Income: $2738 Airbnb ROI: -1.44% Traditional ROI: -1.18%
7571 Wellington Way #1A Clayton, MO Located in the desirable Moorlands neighborhood of Clayton. This 2bed/2 Full bath condo wa...	2 beds \| 2 baths \| 969 sq.ft.	$229,000	Airbnb cash on cash: 1.17% Traditional cash on cash: 2.87% Airbnb Rental Income: $1529 Traditional Rental Income: $1454 Airbnb ROI: 1.17% Traditional ROI: 2.87%
60 Brighton Way #3S Clayton, MO 60 Brighton Way #3S, Clayton, MO 63105 \| Condo/Coop	3 beds \| 3 baths \| 3,388 sq.ft.	$1,674,900	Airbnb cash on cash: -1.85% Traditional cash on cash: -1.93% Airbnb Rental Income: $2508 Traditional Rental Income: $1779 Airbnb ROI: -1.85% Traditional ROI: -1.93%
710 S Hanley Rd #7B Clayton, MO . Stunning views form the 7th floor of the Whitehall, this northern exposure allows spect...	1 beds \| 1 baths \| 1,276 sq.ft.	$205,000	Airbnb cash on cash: -5.04% Traditional cash on cash: -1.81% Airbnb Rental Income: $1105 Traditional Rental Income: $1360 Airbnb ROI: -5.04% Traditional ROI: -1.81%
900 S Hanley Rd #6C Clayton, MO Welcome to unit 6C in the desirable Hanley Towers, ideally located in the heart of Clayton...	2 beds \| 2 baths \| 1,633 sq.ft.	$289,000	Airbnb cash on cash: -5.51% Traditional cash on cash: -2.36% Airbnb Rental Income: $1529 Traditional Rental Income: $1943 Airbnb ROI: -5.51% Traditional ROI: -2.36%
12 E Brentmoor Park Clayton, MO This architecturally significant Mid-Century Modern masterpiece has been thoughtfully and ...	4 beds \| 7 baths \| 5,900 sq.ft.	$3,950,000	Airbnb cash on cash: -1.21% Traditional cash on cash: 0.15% Airbnb Rental Income: $2473 Traditional Rental Income: $6854 Airbnb ROI: -1.21% Traditional ROI: 0.15%
8125 Halifax Dr Clayton, MO 8125 Halifax Dr, Clayton, MO 63105 \| Single Family Residential	3 beds \| 2 baths \| 2,124 sq.ft.	$449,000	Airbnb cash on cash: 2.34% Traditional cash on cash: 2.33% Airbnb Rental Income: $2508 Traditional Rental Income: $1897 Airbnb ROI: 2.34% Traditional ROI: 2.33%
7532 Cromwell Dr #2N Clayton, MO Discover the charm of this highly sought after Moorlands condo, a well maintained second f...	2 beds \| 1 baths \| 1,120 sq.ft.	$209,900	Airbnb cash on cash: 0.32% Traditional cash on cash: 1.73% Airbnb Rental Income: $1529 Traditional Rental Income: $1365 Airbnb ROI: 0.32% Traditional ROI: 1.73%
150 Carondelet Plz #1301 Clayton, MO Experience elevated living at the most coveted address in town- The Plaza in Clayton. This...	2 beds \| 2 baths \| 3,744 sq.ft.	$2,195,000	Airbnb cash on cash: -3.38% Traditional cash on cash: -2.79% Airbnb Rental Income: $1529 Traditional Rental Income: $2275 Airbnb ROI: -3.38% Traditional ROI: -2.79%
7012 Forsyth Blvd #3W Clayton, MO Experience comfort and convenience in this charming 2-bedroom, 1-bath condo just steps fro...	2 beds \| 1 baths \| 840 sq.ft.	$195,000	Airbnb cash on cash: 0.86% Traditional cash on cash: 1.34% Airbnb Rental Income: $1529 Traditional Rental Income: $1175 Airbnb ROI: 0.86% Traditional ROI: 1.34%
7542 York Dr #3E Clayton, MO Step into timeless elegance with this fully updated 2-bedroom, 2-bath condo located in a s...	2 beds \| 2 baths \| 1,309 sq.ft.	$324,900	Airbnb cash on cash: -0.29% Traditional cash on cash: 1.89% Airbnb Rental Income: $1529 Traditional Rental Income: $1752 Airbnb ROI: -0.29% Traditional ROI: 1.89%
250 S Brentwood Blvd #1F Clayton, MO Rare opportunity to own an exceptionally spacious and affordable condo offering more than ...	3 beds \| 2 baths \| 2,249 sq.ft.	$325,000	Airbnb cash on cash: -0.19% Traditional cash on cash: 2.79% Airbnb Rental Income: $2508 Traditional Rental Income: $2811 Airbnb ROI: -0.19% Traditional ROI: 2.79%
31 Dartford Ave Clayton, MO 31 Dartford Ave, Clayton, MO 63105 \| Single Family Residential	4 beds \| 2 baths \| 3,619 sq.ft.	$1,150,000	Airbnb cash on cash: -0.32% Traditional cash on cash: -0.33% Airbnb Rental Income: $2473 Traditional Rental Income: $1856 Airbnb ROI: -0.32% Traditional ROI: -0.33%
250 S Brentwood Blvd #1J Clayton, MO 250 S Brentwood Blvd #1J, Clayton, MO 63105 \| Condo/Coop	2 beds \| 2 baths \| 2,082 sq.ft.	$319,900	Airbnb cash on cash: -2.38% Traditional cash on cash: -0.12% Airbnb Rental Income: $1529 Traditional Rental Income: $1763 Airbnb ROI: -2.38% Traditional ROI: -0.12%

Real Estate investment in Clayton, MO

There are 94 properties for sale in the city of Clayton . The median list price in Clayton is $734,311 and the average price per square foot is $329. In October 2026, the average monthly cash on cash return in Clayton is N/A%. The average monthly rental income in Clayton is $1,973.

Clayton, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 94 investment properties available for sale in Clayton.

In 2026, the best neighborhood to buy investment property is Clayton.

The ROI for Short-Term is higher than the Long-Term in Clayton with average rental income of $2,473.

Your search for investment property begins and ends here

Investment Property for Sale in Clayton, MO

710 S Hanley Rd #10A

Clayton, MO

3 beds | 3 baths | 2,766 sq.ft.

$849,500

Airbnb cash on cash: -2.8%

Traditional cash on cash: -1.42%

Airbnb Rental Income: $2508

Traditional Rental Income: $2996

Airbnb ROI: -2.8%

Traditional ROI: -1.42%

710 S Hanley Rd #10B

Clayton, MO

2 beds | 2 baths | 1,697 sq.ft.

$499,900

Airbnb cash on cash: -3.16%

Traditional cash on cash: -1.06%

Airbnb Rental Income: $1529

Traditional Rental Income: $2067

Airbnb ROI: -3.16%

Traditional ROI: -1.06%

7545 Wellington Way #1A

Clayton, MO

2 beds | 2 baths | 1,417 sq.ft.

$365,000

Airbnb cash on cash: -0.42%

Traditional cash on cash: 2.11%

Airbnb Rental Income: $1529

Traditional Rental Income: $1953

Airbnb ROI: -0.42%

Traditional ROI: 2.11%

923 S Hanley Rd #A

Clayton, MO

1 beds | 1 baths | 767 sq.ft.

$145,000

Airbnb cash on cash: -1.39%

Traditional cash on cash: 0.33%

Airbnb Rental Income: $1105

Traditional Rental Income: $970

Airbnb ROI: -1.39%

Traditional ROI: 0.33%

8025 Maryland Ave #17C

Clayton, MO

3 beds | 3 baths | 3,685 sq.ft.

$4,450,000

Airbnb cash on cash: -1.78%

Traditional cash on cash: -1.68%

Airbnb Rental Income: $2508

Traditional Rental Income: $2298

Airbnb ROI: -1.78%

Traditional ROI: -1.68%

7564 Wydown Blvd #1B

Clayton, MO

2 beds | 2 baths | 1,432 sq.ft.

$440,000

Airbnb cash on cash: -1%

Traditional cash on cash: 0.39%

Airbnb Rental Income: $1529

Traditional Rental Income: $1657

Airbnb ROI: -1%

Traditional ROI: 0.39%

7520 Oxford Dr #2W

Clayton, MO

2 beds | 2 baths | 1,612 sq.ft.

$399,000

Airbnb cash on cash: -0.34%

Traditional cash on cash: 1.48%

Airbnb Rental Income: $1529

Traditional Rental Income: $1769

Airbnb ROI: -0.34%

Traditional ROI: 1.48%

900 S Hanley Rd #11B

Clayton, MO

1 beds | 1 baths | 1,110 sq.ft.

$139,900

Airbnb cash on cash: -8.71%

Traditional cash on cash: -4.75%

Airbnb Rental Income: $1105

Traditional Rental Income: $1263

Airbnb ROI: -8.71%