Real Estate Investment Properties for Sale in De Soto, MO

Looking for investment property in De Soto, MO with high ROI ?

Explore a variety of short-term homes & houses in De Soto, MO. Invest wisely with VRBO & De Soto, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in De Soto, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1491 Veterans Drive De Soto, MO (Seller is excepting back up offers) The seller is relocated out of state for work and is ...	3 beds \| 2 baths \| 1,592 sq.ft.	$185,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.32% Airbnb Rental Income: $null Traditional Rental Income: $1847 Airbnb ROI: N/A Traditional ROI: 8.32%
720 S 3rd Street De Soto, MO This growing family needs more rooms than even this spacious 3 bed 2 bath can offer. That ...	3 beds \| 2 baths \| 1,224 sq.ft.	$239,932	Airbnb cash on cash: N/A Traditional cash on cash: 5.84% Airbnb Rental Income: $null Traditional Rental Income: $1725 Airbnb ROI: N/A Traditional ROI: 5.84%
267 Maple Street De Soto, MO Looking for affordable living? Look no further than this charming home. This 1 bed/1 bath ...	1 beds \| 1 baths \| 768 sq.ft.	$80,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.9% Airbnb Rental Income: $null Traditional Rental Income: $924 Airbnb ROI: N/A Traditional ROI: 8.9%
3 Caroline Court De Soto, MO Life is better at the lake, I promise! You will fall in love with this 5 bedroom, 4 bathro...	5 beds \| 4 baths \| 3,922 sq.ft.	$424,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.31% Airbnb Rental Income: $null Traditional Rental Income: $3439 Airbnb ROI: N/A Traditional ROI: 6.31%
5319 Victory Farm Road De Soto, MO Welcome to your private retreat on 1.8 serene acres in De Soto! This spacious 4-bedroom, 2...	4 beds \| 2 baths \| 1,620 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 9.54% Airbnb Rental Income: $null Traditional Rental Income: $2132 Airbnb ROI: N/A Traditional ROI: 9.54%
3772 GOLDENROD LN De Soto, MO Invest with success and buy through Auction.com. This bank-owned investment property is a ...	2 beds \| 1 baths \| 768 sq.ft.	$130,000	Airbnb cash on cash: 1.6% Traditional cash on cash: 5.5% Airbnb Rental Income: $827 Traditional Rental Income: $989 Airbnb ROI: 1.6% Traditional ROI: 5.5%
3401 FLUCOM RD De Soto, MO Invest with success and buy through Auction.com. This bank-owned investment property is a ...	2 beds \| 1 baths \| 780 sq.ft.	$181,000	Airbnb cash on cash: 0.94% Traditional cash on cash: 4.66% Airbnb Rental Income: $827 Traditional Rental Income: $1141 Airbnb ROI: 0.94% Traditional ROI: 4.66%
221 W Miller Street De Soto, MO Needing a large 4 bed 2 bath home, this might be the one! At this price, seller is providi...	4 beds \| 2 baths \| 1,944 sq.ft.	$215,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.47% Airbnb Rental Income: $null Traditional Rental Income: $2108 Airbnb ROI: N/A Traditional ROI: 8.47%
1553 Hickory Landing De Soto, MO 2 Bedroom and 2 full Bathrooms, Welcome to the Villas at West Ridge. What a great opportu...	2 beds \| 2 baths \| 1,460 sq.ft.	$264,926	Airbnb cash on cash: -0.33% Traditional cash on cash: 4.46% Airbnb Rental Income: $827 Traditional Rental Income: $1698 Airbnb ROI: -0.33% Traditional ROI: 4.46%
1805 Greg Drive De Soto, MO Wonderful Ranch Home TO-BE-BUILT!! with split bedrooms on 4 acres!!! Home will have par...	3 beds \| 2 baths \| 1,500 sq.ft.	$434,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.13% Airbnb Rental Income: $null Traditional Rental Income: $1817 Airbnb ROI: N/A Traditional ROI: 3.13%
300 Valley Place De Soto, MO Nestled in a serene neighborhood, this charming split-level home offers the perfect blend ...	4 beds \| 2 baths \| 1,300 sq.ft.	$229,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.79% Airbnb Rental Income: $null Traditional Rental Income: $1921 Airbnb ROI: N/A Traditional ROI: 6.79%
12767 Deer Hollow De Soto, MO Nestled on 18 acres of breathtaking Missouri landscape, this inviting 3-bedroom, 3-bathroo...	3 beds \| 3 baths \| 1,377 sq.ft.	$434,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.45% Airbnb Rental Income: $null Traditional Rental Income: $2068 Airbnb ROI: N/A Traditional ROI: 3.45%
1561 Hickory Landing De Soto, MO This is a great opportunity to own a brand new villa. This villa already has a stacked f...	3 beds \| 3 baths \| 1,460 sq.ft.	$325,987	Airbnb cash on cash: N/A Traditional cash on cash: 4.33% Airbnb Rental Income: $null Traditional Rental Income: $1944 Airbnb ROI: N/A Traditional ROI: 4.33%
1022 S Second St De Soto, MO MOTIVATED SELLER, make offer! This charming 1 bedroom home features a detached, oversized ...	1 beds \| 1 baths \| 728 sq.ft.	$109,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.99% Airbnb Rental Income: $null Traditional Rental Income: $1107 Airbnb ROI: N/A Traditional ROI: 7.99%
517 N 11th De Soto, MO Wonderful 3 bed, 3 bath home is great neighborhood just waiting for you to move right in. ...	3 beds \| 3 baths \| 1,716 sq.ft.	$234,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.16% Airbnb Rental Income: $null Traditional Rental Income: $2009 Airbnb ROI: N/A Traditional ROI: 7.16%
623 Boyne Street De Soto, MO This is a MAN CAVE/GARAGE and a house that comes with it! It is not just a 2 car garage i...	2 beds \| 1 baths \| 1,210 sq.ft.	$249,000	Airbnb cash on cash: 0.28% Traditional cash on cash: 3.9% Airbnb Rental Income: $827 Traditional Rental Income: $1351 Airbnb ROI: 0.28% Traditional ROI: 3.9%
407 N 11th Street De Soto, MO Welcome to this beautifully maintained 3-bedroom, 2-bathroom home nestled right in the hea...	3 beds \| 2 baths \| 1,118 sq.ft.	$240,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.38% Airbnb Rental Income: $null Traditional Rental Income: $1894 Airbnb ROI: N/A Traditional ROI: 6.38%
176 Briarwood Terrace De Soto, MO Live the Lake & Golf Resort Life Every Day! Welcome to this charming 3-bedroom, 2-bathroom...	3 beds \| 2 baths \| 1,176 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.37% Airbnb Rental Income: $null Traditional Rental Income: $1578 Airbnb ROI: N/A Traditional ROI: 4.37%
13761 Klondike Road De Soto, MO Property is now active - Open house SATURDAY 11am to noon! Seller is contributing $6,000 t...	4 beds \| 1 baths \| 1,624 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.1% Airbnb Rental Income: $null Traditional Rental Income: $1505 Airbnb ROI: N/A Traditional ROI: 5.1%
31 Independence Avenue De Soto, MO BACK ON MARKET AT NO FAULT OF SELLER. BUYER FINANCING FELL APART! The lake life is callin...	3 beds \| 2 baths \| 1,800 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.48% Airbnb Rental Income: $null Traditional Rental Income: $1773 Airbnb ROI: N/A Traditional ROI: 4.48%
614 W Saint Louis Street De Soto, MO Home owners/Investors - House close to town and restaurants. 3bd 1bath house that needs a ...	3 beds \| 1 baths \| 764 sq.ft.	$84,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.8% Airbnb Rental Income: $null Traditional Rental Income: $1156 Airbnb ROI: N/A Traditional ROI: 10.8%
358 N Thomas Street De Soto, MO Beautifully upgraded 4-bed, 3-bath ranch at the end of a quiet cul-de-sac! This light-fill...	4 beds \| 3 baths \| 2,195 sq.ft.	$425,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.31% Airbnb Rental Income: $null Traditional Rental Income: $2461 Airbnb ROI: N/A Traditional ROI: 4.31%
107 Morgan Lake Road De Soto, MO This stunning 1.5-story brick home sits on +/-12 acres (3 lots & flat beautiful pasture wi...	4 beds \| 4 baths \| 4,260 sq.ft.	$879,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.55% Airbnb Rental Income: $null Traditional Rental Income: $3546 Airbnb ROI: N/A Traditional ROI: 2.55%
1533 Hickory Landing De Soto, MO This is the newest development within city limits and it is a great opportunity to own a b...	3 beds \| 2 baths \| 1,604 sq.ft.	$273,850	Airbnb cash on cash: N/A Traditional cash on cash: 5.41% Airbnb Rental Income: $null Traditional Rental Income: $1965 Airbnb ROI: N/A Traditional ROI: 5.41%
1504 Essex Heights Drive De Soto, MO Are you looking for an adorable home move in ready in a great location? This 5 beds, 3 b...	5 beds \| 3 baths \| 1,400 sq.ft.	$284,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.03% Airbnb Rental Income: $null Traditional Rental Income: $1914 Airbnb ROI: N/A Traditional ROI: 5.03%
3870 Wilkinson Road De Soto, MO Escape to peace and privacy on this beautiful 7.46-acre property in DeSoto, featuring a 3-...	3 beds \| 3 baths \| 1,625 sq.ft.	$375,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.79% Airbnb Rental Income: $null Traditional Rental Income: $1943 Airbnb ROI: N/A Traditional ROI: 3.79%
821 N 3rd Street De Soto, MO	2 beds \| 1 baths \| 928 sq.ft.	$139,900	Airbnb cash on cash: 1.61% Traditional cash on cash: 5.91% Airbnb Rental Income: $827 Traditional Rental Income: $1077 Airbnb ROI: 1.61% Traditional ROI: 5.91%
1551 Hickory Landing De Soto, MO This is the newest development within city limits and it is a great opportunity to own a b...	3 beds \| 2 baths \| 1,604 sq.ft.	$287,270	Airbnb cash on cash: N/A Traditional cash on cash: 4.55% Airbnb Rental Income: $null Traditional Rental Income: $1812 Airbnb ROI: N/A Traditional ROI: 4.55%
1037 Wild Raven Road De Soto, MO Great location in beautiful Wildwood Lake Subdivision in DeSoto School District. This home...	4 beds \| 2 baths \| 2,052 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.35% Airbnb Rental Income: $null Traditional Rental Income: $2347 Airbnb ROI: N/A Traditional ROI: 7.35%
13677 Klondike Road De Soto, MO If you are tired of living in a subdivision with HOA fees and would love room for your RV ...	3 beds \| 4 baths \| 2,742 sq.ft.	$530,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.14% Airbnb Rental Income: $null Traditional Rental Income: $2901 Airbnb ROI: N/A Traditional ROI: 4.14%
6734 Breckenridge Farms Road De Soto, MO Welcome to this newly constructed Craftsman-style ranch, perfectly situated on approximate...	3 beds \| 3 baths \| 2,563 sq.ft.	$620,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.02% Airbnb Rental Income: $null Traditional Rental Income: $2731 Airbnb ROI: N/A Traditional ROI: 3.02%
1535 Hickory Landing De Soto, MO 2 Bedroom and 2 full Bathrooms, Welcome to the Villas at West Ridge. What a great opportu...	2 beds \| 2 baths \| 1,460 sq.ft.	$256,891	Airbnb cash on cash: -0.22% Traditional cash on cash: 5.36% Airbnb Rental Income: $827 Traditional Rental Income: $1854 Airbnb ROI: -0.22% Traditional ROI: 5.36%
1029 S Lakeview Drive De Soto, MO Waterfront bliss with your own private dock â and some of the best fishing around! Welco...	4 beds \| 3 baths \| 1,945 sq.ft.	$409,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.73% Airbnb Rental Income: $null Traditional Rental Income: $2533 Airbnb ROI: N/A Traditional ROI: 4.73%

Real Estate investment in De-soto, MO

There are 57 properties for sale in the city of De Soto . The median list price in De Soto is $252,946 and the average price per square foot is $157. In October 2025, the average monthly cash on cash return in De Soto is 6.00%. The average monthly rental income in De Soto is $1,851.

De-soto, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 57 investment properties available for sale in De-soto.

In 2025, the best neighborhood to buy investment property is De Soto.

The ROI for Long-Term is higher than the Short-Term in De-soto with average rental income of $1,851.

Your search for investment property begins and ends here

Investment Property for Sale in De Soto, MO

1491 Veterans Drive

De Soto, MO

3 beds | 2 baths | 1,592 sq.ft.

$185,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.32%

Airbnb Rental Income: $null

Traditional Rental Income: $1847

Airbnb ROI: N/A

Traditional ROI: 8.32%

720 S 3rd Street

De Soto, MO

3 beds | 2 baths | 1,224 sq.ft.

$239,932

Airbnb cash on cash: N/A

Traditional cash on cash: 5.84%

Airbnb Rental Income: $null

Traditional Rental Income: $1725

Airbnb ROI: N/A

Traditional ROI: 5.84%

267 Maple Street

De Soto, MO

1 beds | 1 baths | 768 sq.ft.

$80,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.9%

Airbnb Rental Income: $null

Traditional Rental Income: $924

Airbnb ROI: N/A

Traditional ROI: 8.9%

3 Caroline Court

De Soto, MO

5 beds | 4 baths | 3,922 sq.ft.

$424,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.31%

Airbnb Rental Income: $null

Traditional Rental Income: $3439

Airbnb ROI: N/A

Traditional ROI: 6.31%

5319 Victory Farm Road

De Soto, MO

4 beds | 2 baths | 1,620 sq.ft.

$189,900

Airbnb cash on cash: N/A

Traditional cash on cash: 9.54%

Airbnb Rental Income: $null

Traditional Rental Income: $2132

Airbnb ROI: N/A

Traditional ROI: 9.54%

3772 GOLDENROD LN

De Soto, MO

2 beds | 1 baths | 768 sq.ft.

$130,000

Airbnb cash on cash: 1.6%

Traditional cash on cash: 5.5%

Airbnb Rental Income: $827

Traditional Rental Income: $989

Airbnb ROI: 1.6%

Traditional ROI: 5.5%

3401 FLUCOM RD

De Soto, MO

2 beds | 1 baths | 780 sq.ft.

$181,000

Airbnb cash on cash: 0.94%

Traditional cash on cash: 4.66%

Airbnb Rental Income: $827

Traditional Rental Income: $1141

Airbnb ROI: 0.94%

Traditional ROI: 4.66%

221 W Miller Street

De Soto, MO

4 beds | 2 baths | 1,944 sq.ft.

$215,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.47%

Airbnb Rental Income: $null

Traditional Rental Income: $2108

Airbnb ROI: N/A