Real Estate Investment Properties for Sale in De Soto, MO

Looking for investment property in De Soto, MO with high ROI ?

Explore a variety of short-term homes & houses in De Soto, MO. Invest wisely with VRBO & De Soto, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in De Soto, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4445 Cedar Tree Lane De Soto, MO Welcome to your dream retreat! This spectacular 5-bedroom, 5.1/2-bath estate offers more t...	5 beds \| 6 baths \| 5,073 sq.ft.	$580,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.21% Airbnb Rental Income: $null Traditional Rental Income: $6006 Airbnb ROI: N/A Traditional ROI: 9.21%
13963 Springdale Road De Soto, MO Welcome to 13963 Springdale Rd, a well-maintained 2 bed, 2 bath ranch on more than 5 beaut...	2 beds \| 2 baths \| 2,030 sq.ft.	$295,000	Airbnb cash on cash: 0.4% Traditional cash on cash: 5.94% Airbnb Rental Income: $1022 Traditional Rental Income: $2203 Airbnb ROI: 0.4% Traditional ROI: 5.94%
1571 Berry Dairy Road De Soto, MO Welcome to your new home! This 4-bedroom, 2-bath home that perfectly blends comfort, funct...	4 beds \| 2 baths \| 1,200 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.87% Airbnb Rental Income: $null Traditional Rental Income: $1671 Airbnb ROI: N/A Traditional ROI: 5.87%
330 Kronos Drive De Soto, MO Back on the market at NO fault of the seller! Sellers are motivatedâcome tour today! T...	3 beds \| 1 baths \| 2,080 sq.ft.	$220,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.36% Airbnb Rental Income: $null Traditional Rental Income: $1503 Airbnb ROI: N/A Traditional ROI: 5.36%
3772 GOLDENROD LN De Soto, MO Invest with success and buy through Auction.com. This bank-owned investment property is a ...	2 beds \| 1 baths \| 768 sq.ft.	$130,000	Airbnb cash on cash: 2.9% Traditional cash on cash: 5.5% Airbnb Rental Income: $1022 Traditional Rental Income: $989 Airbnb ROI: 2.9% Traditional ROI: 5.5%
3401 FLUCOM RD De Soto, MO Invest with success and buy through Auction.com. This bank-owned investment property is a ...	2 beds \| 1 baths \| 780 sq.ft.	$181,000	Airbnb cash on cash: 1.89% Traditional cash on cash: 4.66% Airbnb Rental Income: $1022 Traditional Rental Income: $1141 Airbnb ROI: 1.89% Traditional ROI: 4.66%
14147 Timberline Drive De Soto, MO Introducing a freshly spruced-up gem nestled in the tranquil Valle Lake neighborhood! This...	2 beds \| 1 baths \| 1,000 sq.ft.	$158,700	Airbnb cash on cash: 2.04% Traditional cash on cash: 4.08% Airbnb Rental Income: $1022 Traditional Rental Income: $973 Airbnb ROI: 2.04% Traditional ROI: 4.08%
221 W Miller Street De Soto, MO Price Improved! Needing a large 4 bed 2 bath home, this might be the one! Beautifully ren...	4 beds \| 2 baths \| 1,944 sq.ft.	$205,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.92% Airbnb Rental Income: $null Traditional Rental Income: $2108 Airbnb ROI: N/A Traditional ROI: 8.92%
1553 Hickory Landing De Soto, MO 2 Bedroom and 2 full Bathrooms, Welcome to the Villas at West Ridge. What a great opportu...	2 beds \| 2 baths \| 1,460 sq.ft.	$264,926	Airbnb cash on cash: 0.32% Traditional cash on cash: 4.46% Airbnb Rental Income: $1022 Traditional Rental Income: $1698 Airbnb ROI: 0.32% Traditional ROI: 4.46%
1208 Boyd Street De Soto, MO Recently updated home with a great blend of modern finishes with older style. This 3 bedro...	3 beds \| 2 baths \| 1,336 sq.ft.	$219,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.38% Airbnb Rental Income: $null Traditional Rental Income: $2146 Airbnb ROI: N/A Traditional ROI: 8.38%
12753 Hencher Road De Soto, MO	2 beds \| 1 baths \| 948 sq.ft.	$135,000	Airbnb cash on cash: 2.63% Traditional cash on cash: 6.43% Airbnb Rental Income: $1022 Traditional Rental Income: $1156 Airbnb ROI: 2.63% Traditional ROI: 6.43%
623 Boyne Street De Soto, MO This is a MAN CAVE/GARAGE and a house that comes with it! It is not just a 2 car garage i...	2 beds \| 1 baths \| 1,210 sq.ft.	$249,000	Airbnb cash on cash: 0.97% Traditional cash on cash: 3.9% Airbnb Rental Income: $1022 Traditional Rental Income: $1351 Airbnb ROI: 0.97% Traditional ROI: 3.9%
407 N 11th Street De Soto, MO Welcome to this beautifully maintained 3-bedroom, 2-bathroom home nestled right in the hea...	3 beds \| 2 baths \| 1,118 sq.ft.	$230,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.69% Airbnb Rental Income: $null Traditional Rental Income: $1894 Airbnb ROI: N/A Traditional ROI: 6.69%
176 Briarwood Terrace De Soto, MO Live the Lake & Golf Resort Life Every Day! Welcome to this charming 3-bedroom, 2-bathroom...	3 beds \| 2 baths \| 1,176 sq.ft.	$245,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.69% Airbnb Rental Income: $null Traditional Rental Income: $1578 Airbnb ROI: N/A Traditional ROI: 4.69%
614 W Saint Louis Street De Soto, MO Home owners/Investors - House close to town and restaurants. 3bd 1bath house that needs a ...	3 beds \| 1 baths \| 764 sq.ft.	$84,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.8% Airbnb Rental Income: $null Traditional Rental Income: $1156 Airbnb ROI: N/A Traditional ROI: 10.8%
107 Morgan Lake Road De Soto, MO Motivated Seller! This stunning 1.5-story brick home sits on +/-4.04 acres (additional acr...	4 beds \| 4 baths \| 4,260 sq.ft.	$749,999	Airbnb cash on cash: N/A Traditional cash on cash: 3.16% Airbnb Rental Income: $null Traditional Rental Income: $3546 Airbnb ROI: N/A Traditional ROI: 3.16%
1533 Hickory Landing De Soto, MO This is the newest development within city limits and it is a great opportunity to own a b...	3 beds \| 2 baths \| 1,604 sq.ft.	$273,850	Airbnb cash on cash: N/A Traditional cash on cash: 5.41% Airbnb Rental Income: $null Traditional Rental Income: $1965 Airbnb ROI: N/A Traditional ROI: 5.41%
1504 Essex Heights Drive De Soto, MO Are you looking for an adorable home move in ready in a great location? This 5 beds, 3 b...	5 beds \| 3 baths \| 1,400 sq.ft.	$284,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.03% Airbnb Rental Income: $null Traditional Rental Income: $1914 Airbnb ROI: N/A Traditional ROI: 5.03%
821 N 3rd Street De Soto, MO	2 beds \| 1 baths \| 928 sq.ft.	$139,900	Airbnb cash on cash: 2.82% Traditional cash on cash: 5.91% Airbnb Rental Income: $1022 Traditional Rental Income: $1077 Airbnb ROI: 2.82% Traditional ROI: 5.91%
1551 Hickory Landing De Soto, MO This is the newest development within city limits and it is a great opportunity to own a b...	3 beds \| 2 baths \| 1,604 sq.ft.	$287,270	Airbnb cash on cash: N/A Traditional cash on cash: 4.55% Airbnb Rental Income: $null Traditional Rental Income: $1812 Airbnb ROI: N/A Traditional ROI: 4.55%
6734 Breckenridge Farms Road De Soto, MO Welcome to this newly constructed Craftsman-style ranch, perfectly situated on approximate...	3 beds \| 3 baths \| 2,563 sq.ft.	$600,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.15% Airbnb Rental Income: $null Traditional Rental Income: $2731 Airbnb ROI: N/A Traditional ROI: 3.15%
1535 Hickory Landing De Soto, MO 2 Bedroom and 2 full Bathrooms, Welcome to the Villas at West Ridge. What a great opportu...	2 beds \| 2 baths \| 1,460 sq.ft.	$256,891	Airbnb cash on cash: 0.45% Traditional cash on cash: 5.36% Airbnb Rental Income: $1022 Traditional Rental Income: $1854 Airbnb ROI: 0.45% Traditional ROI: 5.36%
1029 S Lakeview Drive De Soto, MO Waterfront bliss with your own private dock â and some of the best fishing around! Welco...	4 beds \| 3 baths \| 1,945 sq.ft.	$379,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.18% Airbnb Rental Income: $null Traditional Rental Income: $2533 Airbnb ROI: N/A Traditional ROI: 5.18%
4211 Old Road De Soto, MO Charming Ranch on Wooded 3/4 Acre Lot â AS-IS Opportunity! Discover the potential in thi...	2 beds \| 1 baths \| 1,300 sq.ft.	$100,000	Airbnb cash on cash: 3.74% Traditional cash on cash: 11.36% Airbnb Rental Income: $1022 Traditional Rental Income: $1403 Airbnb ROI: 3.74% Traditional ROI: 11.36%
97 E Lakeview Drive De Soto, MO Rare investment opportunity in the gated lake community of Summer Set! Log cabin fixer-upp...	2 beds \| 3 baths \| 1,633 sq.ft.	$160,000	Airbnb cash on cash: 1.34% Traditional cash on cash: 9.36% Airbnb Rental Income: $1022 Traditional Rental Income: $1888 Airbnb ROI: 1.34% Traditional ROI: 9.36%
716 W Saint Louis Street De Soto, MO Property is back on the market not because of any inspections. Perfect opportunity to own ...	2 beds \| 1 baths \| 832 sq.ft.	$110,000	Airbnb cash on cash: 3.76% Traditional cash on cash: 8.93% Airbnb Rental Income: $1022 Traditional Rental Income: $1213 Airbnb ROI: 3.76% Traditional ROI: 8.93%
1650 Brandywine De Soto, MO Newly constructed 3 bedroom 2 bath home with many features! The 3 car garage is fully dryw...	3 beds \| 2 baths \| 1,600 sq.ft.	$389,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.92% Airbnb Rental Income: $null Traditional Rental Income: $1945 Airbnb ROI: N/A Traditional ROI: 3.92%
211 Easy Street De Soto, MO MOTIVATED SELLER USDA ELIGIBLELife really is easier on Easy Street. This brand-new...	3 beds \| 2 baths \| 1,600 sq.ft.	$320,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.97% Airbnb Rental Income: $null Traditional Rental Income: $1945 Airbnb ROI: N/A Traditional ROI: 4.97%
2714 Ganymedes De Soto, MO This awesome 3 bed 3 bath home sits on 2.21 acres. It is a 2 story with kitchen, dining r...	3 beds \| 3 baths \| 1,600 sq.ft.	$259,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.46% Airbnb Rental Income: $null Traditional Rental Income: $2039 Airbnb ROI: N/A Traditional ROI: 6.46%
5 Eva Drive De Soto, MO Welcome to 5 Eva Drive in the sought-after Summer Set Lake Community of DeSoto, MO! This c...	3 beds \| 2 baths \| 924 sq.ft.	$184,999	Airbnb cash on cash: N/A Traditional cash on cash: 5.28% Airbnb Rental Income: $null Traditional Rental Income: $1382 Airbnb ROI: N/A Traditional ROI: 5.28%

Real Estate investment in De-soto, MO

There are 47 properties for sale in the city of De Soto . The median list price in De Soto is $227,500 and the average price per square foot is $140. In December 2025, the average monthly cash on cash return in De Soto is 5.00%. The average monthly rental income in De Soto is $1,804.

De-soto, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 47 investment properties available for sale in De-soto.

In 2025, the best neighborhood to buy investment property is De Soto.

The ROI for Long-Term is higher than the Short-Term in De-soto with average rental income of $1,804.

Your search for investment property begins and ends here

Investment Property for Sale in De Soto, MO

4445 Cedar Tree Lane

De Soto, MO

5 beds | 6 baths | 5,073 sq.ft.

$580,000

Airbnb cash on cash: N/A

Traditional cash on cash: 9.21%

Airbnb Rental Income: $null

Traditional Rental Income: $6006

Airbnb ROI: N/A

Traditional ROI: 9.21%

13963 Springdale Road

De Soto, MO

2 beds | 2 baths | 2,030 sq.ft.

$295,000

Airbnb cash on cash: 0.4%

Traditional cash on cash: 5.94%

Airbnb Rental Income: $1022

Traditional Rental Income: $2203

Airbnb ROI: 0.4%

Traditional ROI: 5.94%

1571 Berry Dairy Road

De Soto, MO

4 beds | 2 baths | 1,200 sq.ft.

$225,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.87%

Airbnb Rental Income: $null

Traditional Rental Income: $1671

Airbnb ROI: N/A

Traditional ROI: 5.87%

330 Kronos Drive

De Soto, MO

3 beds | 1 baths | 2,080 sq.ft.

$220,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.36%

Airbnb Rental Income: $null

Traditional Rental Income: $1503

Airbnb ROI: N/A

Traditional ROI: 5.36%

3772 GOLDENROD LN

De Soto, MO

2 beds | 1 baths | 768 sq.ft.

$130,000

Airbnb cash on cash: 2.9%

Traditional cash on cash: 5.5%

Airbnb Rental Income: $1022

Traditional Rental Income: $989

Airbnb ROI: 2.9%

Traditional ROI: 5.5%

3401 FLUCOM RD

De Soto, MO

2 beds | 1 baths | 780 sq.ft.

$181,000

Airbnb cash on cash: 1.89%

Traditional cash on cash: 4.66%

Airbnb Rental Income: $1022

Traditional Rental Income: $1141

Airbnb ROI: 1.89%

Traditional ROI: 4.66%

14147 Timberline Drive

De Soto, MO

2 beds | 1 baths | 1,000 sq.ft.

$158,700

Airbnb cash on cash: 2.04%

Traditional cash on cash: 4.08%

Airbnb Rental Income: $1022

Traditional Rental Income: $973

Airbnb ROI: 2.04%

Traditional ROI: 4.08%

221 W Miller Street

De Soto, MO

4 beds | 2 baths | 1,944 sq.ft.

$205,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.92%

Airbnb Rental Income: $null

Traditional Rental Income: $2108

Airbnb ROI: N/A