Real Estate Investment Properties for Sale in Doniphan, MO

Looking for investment property in Doniphan, MO with high ROI ?

Explore a variety of short-term homes & houses in Doniphan, MO. Invest wisely with VRBO & Doniphan, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Doniphan, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4396 State Highway 21 Doniphan, MO PRICE IMPROVEMENT!! Remarkable Home within 5 minutes of Doniphan! This 3,(possibly 4) bedr...	3 beds \| 2 baths \| 2,064 sq.ft.	$254,900	Airbnb cash on cash: -0.84% Traditional cash on cash: 7.07% Airbnb Rental Income: $443 Traditional Rental Income: $2084 Airbnb ROI: -0.84% Traditional ROI: 7.07%
4795 Ripley K-1 Doniphan, MO MOTIVATED SELLER-----Built in 2024, this beautiful 4-bedroom, 2-bath home offers modern co...	4 beds \| 2 baths \| 1,800 sq.ft.	$268,000	Airbnb cash on cash: 5.12% Traditional cash on cash: 6.05% Airbnb Rental Income: $2319 Traditional Rental Income: $1978 Airbnb ROI: 5.12% Traditional ROI: 6.05%
1092 Ripley E1-A Doniphan, MO Nestled atop a scenic hillside and surrounded by 15 +/- surveyed acres, this stunning mode...	5 beds \| 5 baths \| 4,624 sq.ft.	$629,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.29% Airbnb Rental Income: $null Traditional Rental Income: $5163 Airbnb ROI: N/A Traditional ROI: 7.29%
1901 River Valley Road Doniphan, MO CURRENT RIVER CABIN - RIVERFRONT, 2 ACRES, MINUTES FROM DONIPHAN Experience the beauty of...	3 beds \| 3 baths \| 1,834 sq.ft.	$674,900	Airbnb cash on cash: -1.15% Traditional cash on cash: 2.6% Airbnb Rental Income: $443 Traditional Rental Income: $2540 Airbnb ROI: -1.15% Traditional ROI: 2.6%
6029 Ripley Rt V Doniphan, MO Breath-taking home on 6.5 acres (m/l) on top of the hill! You have to see this 3067 sq ft ...	3 beds \| 3 baths \| 3,067 sq.ft.	$399,000	Airbnb cash on cash: -1.1% Traditional cash on cash: 5.42% Airbnb Rental Income: $443 Traditional Rental Income: $2619 Airbnb ROI: -1.1% Traditional ROI: 5.42%
936 Crawdad Lane Doniphan, MO Private 75-Acre Estate with Lake, 3 Homes & borders Government Forest . A private Lakefro...	4 beds \| 2 baths \| 2,997 sq.ft.	$749,900	Airbnb cash on cash: 1.17% Traditional cash on cash: 2.51% Airbnb Rental Income: $2319 Traditional Rental Income: $2677 Airbnb ROI: 1.17% Traditional ROI: 2.51%
1300 River Valley Road Doniphan, MO Experience refined riverfront living in this exceptional 4 bedroom, 3 bath contemporary ca...	4 beds \| 3 baths \| 1,768 sq.ft.	$625,000	Airbnb cash on cash: 1.61% Traditional cash on cash: 3.3% Airbnb Rental Income: $2319 Traditional Rental Income: $2732 Airbnb ROI: 1.61% Traditional ROI: 3.3%
1457 Riverway Drive Doniphan, MO Escape to modern luxury in this Riverfront cabin retreat! Welcome to your dream getaway- a...	5 beds \| 2 baths \| 2,480 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $2605 Airbnb ROI: N/A Traditional ROI: 3.86%
113 Ripley 142E-17 Doniphan, MO Tucked away just east of Doniphan at the end of a quiet dead-end road, this charming 3-bed...	3 beds \| 2 baths \| 1,444 sq.ft.	$225,900	Airbnb cash on cash: -1% Traditional cash on cash: 6.66% Airbnb Rental Income: $443 Traditional Rental Income: $1817 Airbnb ROI: -1% Traditional ROI: 6.66%
2225 Us Highway 160 Doniphan, MO Very attractive well maintained 3 bed- 2 full bath home, new granite counter tops and new ...	3 beds \| 2 baths \| 1,280 sq.ft.	$179,000	Airbnb cash on cash: -0.59% Traditional cash on cash: 8.55% Airbnb Rental Income: $443 Traditional Rental Income: $1737 Airbnb ROI: -0.59% Traditional ROI: 8.55%
8858 State Hwy 142W Doniphan, MO Welcome to your private escape, tucked away at the end of a beautiful, wooded driveway. S...	3 beds \| 2 baths \| 1,282 sq.ft.	$250,000	Airbnb cash on cash: -0.92% Traditional cash on cash: 5.28% Airbnb Rental Income: $443 Traditional Rental Income: $1645 Airbnb ROI: -0.92% Traditional ROI: 5.28%
607 Wanda Road Doniphan, MO This beautifully remodeled 3 bedroom, 2 bath home offers a perfect blend of modern comfort...	3 beds \| 2 baths \| 1,444 sq.ft.	$189,500	Airbnb cash on cash: -0.78% Traditional cash on cash: 6.19% Airbnb Rental Income: $443 Traditional Rental Income: $1436 Airbnb ROI: -0.78% Traditional ROI: 6.19%
4375 State Highway 142 east Doniphan, MO Charming 3 Bedroom Brick Home Near Current River! Looking for peaceful country living j...	3 beds \| 2 baths \| 1,956 sq.ft.	$205,500	Airbnb cash on cash: -0.9% Traditional cash on cash: 9.24% Airbnb Rental Income: $443 Traditional Rental Income: $2156 Airbnb ROI: -0.9% Traditional ROI: 9.24%
1008 Barton Road Doniphan, MO Take a look at this newly remodeled home on the edge of city limits just outside of Doniph...	3 beds \| 3 baths \| 2,324 sq.ft.	$259,500	Airbnb cash on cash: -0.93% Traditional cash on cash: 9.2% Airbnb Rental Income: $443 Traditional Rental Income: $2662 Airbnb ROI: -0.93% Traditional ROI: 9.2%
13 Walleye Lane Doniphan, MO Turn-Key 3BR Log Cabin on the Current River - No Flood Risk - Fully FurnishedBeautifully m...	3 beds \| 1 baths \| 1,200 sq.ft.	$444,900	Airbnb cash on cash: -0.87% Traditional cash on cash: 0.88% Airbnb Rental Income: $443 Traditional Rental Income: $910 Airbnb ROI: -0.87% Traditional ROI: 0.88%
408 4th Street Doniphan, MO Check out this beautifully updated 3-bedroom, 1-bath home located on a spacious corner lot...	3 beds \| 1 baths \| 990 sq.ft.	$110,000	Airbnb cash on cash: -1.14% Traditional cash on cash: 6.03% Airbnb Rental Income: $443 Traditional Rental Income: $943 Airbnb ROI: -1.14% Traditional ROI: 6.03%
243 Big Pine Road Doniphan, MO Escape to the peace and privacy of country living on 3.49 +/- acres surrounded by woods an...	3 beds \| 2 baths \| 1,860 sq.ft.	$339,900	Airbnb cash on cash: -1.05% Traditional cash on cash: 4.07% Airbnb Rental Income: $443 Traditional Rental Income: $1815 Airbnb ROI: -1.05% Traditional ROI: 4.07%
394 Violet Ln Doniphan, MO Welcome to your FULLY FURNISHED, private riverfront paradise on the beautiful Current Rive...	4 beds \| 4 baths \| 3,599 sq.ft.	$1,349,900	Airbnb cash on cash: 0.07% Traditional cash on cash: 1.82% Airbnb Rental Income: $2319 Traditional Rental Income: $3943 Airbnb ROI: 0.07% Traditional ROI: 1.82%
2977 Ripley Route A Doniphan, MO Price Improvement! Very attractive 1,800 sq. ft. modular home, with metal roof, built in 2...	3 beds \| 2 baths \| 1,800 sq.ft.	$219,900	Airbnb cash on cash: -0.8% Traditional cash on cash: 7.9% Airbnb Rental Income: $443 Traditional Rental Income: $1992 Airbnb ROI: -0.8% Traditional ROI: 7.9%
1004 Barton Road Doniphan, MO Check out this really nice affordable home just outside the city limits of Doniphan! This ...	3 beds \| 2 baths \| 2,016 sq.ft.	$189,500	Airbnb cash on cash: -0.92% Traditional cash on cash: 9.56% Airbnb Rental Income: $443 Traditional Rental Income: $2068 Airbnb ROI: -0.92% Traditional ROI: 9.56%
38 Ripley E #U4-B Doniphan, MO Set within a gated community along the famed Current River in Doniphan, The Riverbend Cott...	3 beds \| 2 baths \| 1,456 sq.ft.	$409,000	Airbnb cash on cash: -1.07% Traditional cash on cash: 2.23% Airbnb Rental Income: $443 Traditional Rental Income: $1444 Airbnb ROI: -1.07% Traditional ROI: 2.23%
207 Jackson Street Doniphan, MO Quaint two-bedroom, one-bath home located just minutes from Current River and in city limi...	2 beds \| 1 baths \| 928 sq.ft.	$125,000	Airbnb cash on cash: -0.93% Traditional cash on cash: 7.49% Airbnb Rental Income: $382 Traditional Rental Income: $1144 Airbnb ROI: -0.93% Traditional ROI: 7.49%
201 Ripley E-4 Doniphan, MO This home has been completely renovated from top to bottom-giving you the charm of a river...	3 beds \| 2 baths \| 1,900 sq.ft.	$209,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 8.72% Airbnb Rental Income: $443 Traditional Rental Income: $2113 Airbnb ROI: -1.04% Traditional ROI: 8.72%
220 Ripley 160E-8 Doniphan, MO Welcome home to this charming 3-bedroom, 2.5-bath gem featuring a super cute open floor pl...	3 beds \| 3 baths \| 2,000 sq.ft.	$209,900	Airbnb cash on cash: -0.88% Traditional cash on cash: 8.73% Airbnb Rental Income: $443 Traditional Rental Income: $2092 Airbnb ROI: -0.88% Traditional ROI: 8.73%
286 Ripley O-3 Doniphan, MO Completely remodeled four bedroom 2 bath home on 5 acres m/l with beautiful pond views. Th...	4 beds \| 2 baths \| 1,728 sq.ft.	$299,900	Airbnb cash on cash: 4.67% Traditional cash on cash: 5.59% Airbnb Rental Income: $2319 Traditional Rental Income: $2001 Airbnb ROI: 4.67% Traditional ROI: 5.59%
1137 Riverlawn Drive Doniphan, MO Welcome to Patriots Pointâyour private slice of paradise on the Current River. With over...	4 beds \| 2 baths \| 1,560 sq.ft.	$699,900	Airbnb cash on cash: 1.38% Traditional cash on cash: 1.86% Airbnb Rental Income: $2319 Traditional Rental Income: $2056 Airbnb ROI: 1.38% Traditional ROI: 1.86%
509 Plum Street Doniphan, MO Looking for an investment property or a first time home? Freshly remodeled, this is a 1 be...	1 beds \| 1 baths \| 936 sq.ft.	$79,900	Airbnb cash on cash: 9.37% Traditional cash on cash: 10.54% Airbnb Rental Income: $1342 Traditional Rental Income: $1021 Airbnb ROI: 9.37% Traditional ROI: 10.54%
7687 Ripley Route A Doniphan, MO Country Living With Multi-Generational Potential on 6 Acres Bring your horses, start your ...	4 beds \| 2 baths \| 1,828 sq.ft.	$179,900	Airbnb cash on cash: 8.32% Traditional cash on cash: 10.07% Airbnb Rental Income: $2319 Traditional Rental Income: $2043 Airbnb ROI: 8.32% Traditional ROI: 10.07%
19 Fox Dr. Doniphan, MO Check out this remarkable home on the edge of city limits in Doniphan on the desirable Fox...	5 beds \| 4 baths \| 3,460 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.95% Airbnb Rental Income: $null Traditional Rental Income: $3691 Airbnb ROI: N/A Traditional ROI: 5.95%
4286 Ripley A-2 Doniphan, MO Check out this beautiful home on 12.5 +/- acres outside of Doniphan, MO!! This larger home...	3 beds \| 2 baths \| 1,598 sq.ft.	$360,000	Airbnb cash on cash: -0.96% Traditional cash on cash: 3.13% Airbnb Rental Income: $443 Traditional Rental Income: $1562 Airbnb ROI: -0.96% Traditional ROI: 3.13%
157 Lily Lane Doniphan, MO Stunning 4 bed, 2 bath home with a view of gorgeous Current River but well above the 2017 ...	4 beds \| 2 baths \| 1,891 sq.ft.	$349,900	Airbnb cash on cash: 3.82% Traditional cash on cash: 3.94% Airbnb Rental Income: $2319 Traditional Rental Income: $1783 Airbnb ROI: 3.82% Traditional ROI: 3.94%
82 Ripley 142E-32C Doniphan, MO Just remodeled and super sharp! This 4 bed, 2 bath home (plus an office!) looks brand new ...	4 beds \| 2 baths \| 1,860 sq.ft.	$249,000	Airbnb cash on cash: 5.66% Traditional cash on cash: 6.98% Airbnb Rental Income: $2319 Traditional Rental Income: $2054 Airbnb ROI: 5.66% Traditional ROI: 6.98%
3061 Ripley Route K Doniphan, MO Escape to tour your own Ozark retreat! Nestled on approximately 20 acres, this custom hand...	3 beds \| 2 baths \| 2,582 sq.ft.	$229,900	Airbnb cash on cash: -0.8% Traditional cash on cash: 5.34% Airbnb Rental Income: $443 Traditional Rental Income: $1516 Airbnb ROI: -0.8% Traditional ROI: 5.34%
2197 State Highway 142 West Doniphan, MO You've noticed and admired this home for years. Now is your chance to make it yours! This ...	4 beds \| 3 baths \| 2,511 sq.ft.	$369,000	Airbnb cash on cash: 3.51% Traditional cash on cash: 7.15% Airbnb Rental Income: $2319 Traditional Rental Income: $3004 Airbnb ROI: 3.51% Traditional ROI: 7.15%
4778 St Hwy 142W Doniphan, MO Spacious Country Home on 7.5 +/- Acres Welcome to this roomy and inviting 4 bedroom, 2 bat...	4 beds \| 2 baths \| 2,330 sq.ft.	$280,000	Airbnb cash on cash: 4.3% Traditional cash on cash: 6.27% Airbnb Rental Income: $2319 Traditional Rental Income: $2266 Airbnb ROI: 4.3% Traditional ROI: 6.27%
106 Sunfish Lane Doniphan, MO Luxury Living on 4 Private Acres \| No Neighboring Homes in Sight Tucked away at the end of...	5 beds \| 4 baths \| 3,600 sq.ft.	$499,999	Airbnb cash on cash: N/A Traditional cash on cash: 6.39% Airbnb Rental Income: $null Traditional Rental Income: $3674 Airbnb ROI: N/A Traditional ROI: 6.39%
406 Miller Street Doniphan, MO Very sharp 3 bed brick home in a quiet neighborhood on a dead end street! Close to everyth...	3 beds \| 1 baths \| 1,250 sq.ft.	$150,000	Airbnb cash on cash: -0.79% Traditional cash on cash: 5.21% Airbnb Rental Income: $443 Traditional Rental Income: $1042 Airbnb ROI: -0.79% Traditional ROI: 5.21%
1103 Cherry Street Doniphan, MO This is the listing that everyone will be talking about. It's a Doniphan landmark. Sitting...	4 beds \| 3 baths \| 6,280 sq.ft.	$349,000	Airbnb cash on cash: 3.46% Traditional cash on cash: 6.56% Airbnb Rental Income: $2319 Traditional Rental Income: $2757 Airbnb ROI: 3.46% Traditional ROI: 6.56%

Real Estate investment in Doniphan, MO

There are 43 properties for sale in the city of Doniphan . The median list price in Doniphan is $116,830 and the average price per square foot is $60. In July 2026, the average monthly cash on cash return in Doniphan is 7.00%. The average monthly rental income in Doniphan is $1,997.

Doniphan, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 43 investment properties available for sale in Doniphan.

In 2026, the best neighborhood to buy investment property is Doniphan.

The ROI for Long-Term is higher than the Short-Term in Doniphan with average rental income of $1,997.

Your search for investment property begins and ends here

Investment Property for Sale in Doniphan, MO

4396 State Highway 21

Doniphan, MO

3 beds | 2 baths | 2,064 sq.ft.

$254,900

Airbnb cash on cash: -0.84%

Traditional cash on cash: 7.07%

Airbnb Rental Income: $443

Traditional Rental Income: $2084

Airbnb ROI: -0.84%

Traditional ROI: 7.07%

4795 Ripley K-1

Doniphan, MO

4 beds | 2 baths | 1,800 sq.ft.

$268,000

Airbnb cash on cash: 5.12%

Traditional cash on cash: 6.05%

Airbnb Rental Income: $2319

Traditional Rental Income: $1978

Airbnb ROI: 5.12%

Traditional ROI: 6.05%

1092 Ripley E1-A

Doniphan, MO

5 beds | 5 baths | 4,624 sq.ft.

$629,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.29%

Airbnb Rental Income: $null

Traditional Rental Income: $5163

Airbnb ROI: N/A

Traditional ROI: 7.29%

1901 River Valley Road

Doniphan, MO

3 beds | 3 baths | 1,834 sq.ft.

$674,900

Airbnb cash on cash: -1.15%

Traditional cash on cash: 2.6%

Airbnb Rental Income: $443

Traditional Rental Income: $2540

Airbnb ROI: -1.15%

Traditional ROI: 2.6%

6029 Ripley Rt V

Doniphan, MO

3 beds | 3 baths | 3,067 sq.ft.

$399,000

Airbnb cash on cash: -1.1%

Traditional cash on cash: 5.42%

Airbnb Rental Income: $443

Traditional Rental Income: $2619

Airbnb ROI: -1.1%

Traditional ROI: 5.42%

936 Crawdad Lane

Doniphan, MO

4 beds | 2 baths | 2,997 sq.ft.

$749,900

Airbnb cash on cash: 1.17%

Traditional cash on cash: 2.51%

Airbnb Rental Income: $2319

Traditional Rental Income: $2677

Airbnb ROI: 1.17%

Traditional ROI: 2.51%

1300 River Valley Road

Doniphan, MO

4 beds | 3 baths | 1,768 sq.ft.

$625,000

Airbnb cash on cash: 1.61%

Traditional cash on cash: 3.3%

Airbnb Rental Income: $2319

Traditional Rental Income: $2732

Airbnb ROI: 1.61%

Traditional ROI: 3.3%

1457 Riverway Drive

Doniphan, MO

5 beds | 2 baths | 2,480 sq.ft.

$525,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.86%

Airbnb Rental Income: $null

Traditional Rental Income: $2605

Airbnb ROI: N/A