Real Estate Investment Properties for Sale in Doniphan, MO

Looking for investment property in Doniphan, MO with high ROI ?

Explore a variety of short-term homes & houses in Doniphan, MO. Invest wisely with VRBO & Doniphan, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Doniphan, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4396 State Highway 21 Doniphan, MO Remarkable Home within 5 minutes of Doniphan! This 3,(possibly 4) bedroom, 2 bath home on ...	3 beds \| 2 baths \| 2,064 sq.ft.	$269,900	Airbnb cash on cash: -0.95% Traditional cash on cash: 6.63% Airbnb Rental Income: $413 Traditional Rental Income: $2084 Airbnb ROI: -0.95% Traditional ROI: 6.63%
4795 Ripley K-1 Doniphan, MO MOTIVATED SELLER-----Built in 2024, this beautiful 4-bedroom, 2-bath home offers modern co...	4 beds \| 2 baths \| 1,800 sq.ft.	$274,999	Airbnb cash on cash: 3.85% Traditional cash on cash: 5.87% Airbnb Rental Income: $1970 Traditional Rental Income: $1978 Airbnb ROI: 3.85% Traditional ROI: 5.87%
1092 Ripley E1-A Doniphan, MO Nestled atop a scenic hillside and surrounded by 15 +/- surveyed acres, this stunning mode...	5 beds \| 5 baths \| 4,624 sq.ft.	$649,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.04% Airbnb Rental Income: $null Traditional Rental Income: $5163 Airbnb ROI: N/A Traditional ROI: 7.04%
1901 River Valley Road Doniphan, MO CURRENT RIVER CABIN - RIVERFRONT, 2 ACRES, MINUTES FROM DONIPHAN Experience the beauty of...	3 beds \| 3 baths \| 1,834 sq.ft.	$674,900	Airbnb cash on cash: -1.19% Traditional cash on cash: 2.6% Airbnb Rental Income: $413 Traditional Rental Income: $2540 Airbnb ROI: -1.19% Traditional ROI: 2.6%
406 Miller Street Doniphan, MO Very sharp 3 bed brick home in a quiet neighborhood on a dead end street! Close to everyth...	3 beds \| 1 baths \| 1,250 sq.ft.	$150,000	Airbnb cash on cash: -0.96% Traditional cash on cash: 5.21% Airbnb Rental Income: $413 Traditional Rental Income: $1042 Airbnb ROI: -0.96% Traditional ROI: 5.21%
6029 Ripley Rt V Doniphan, MO Breath-taking home on 6.5 acres (m/l) on top of the hill! You have to see this 3067 sq ft ...	3 beds \| 3 baths \| 3,067 sq.ft.	$399,000	Airbnb cash on cash: -1.17% Traditional cash on cash: 5.42% Airbnb Rental Income: $413 Traditional Rental Income: $2619 Airbnb ROI: -1.17% Traditional ROI: 5.42%
936 Crawdad Lane Doniphan, MO Private 75-Acre Estate with Lake, 3 Homes & borders Government Forest . A private Lakefro...	4 beds \| 2 baths \| 2,997 sq.ft.	$749,900	Airbnb cash on cash: 0.76% Traditional cash on cash: 2.51% Airbnb Rental Income: $1970 Traditional Rental Income: $2677 Airbnb ROI: 0.76% Traditional ROI: 2.51%
1103 Cherry Street Doniphan, MO This is the listing that everyone will be talking about. It's a Doniphan landmark. Sitting...	4 beds \| 3 baths \| 6,280 sq.ft.	$349,000	Airbnb cash on cash: 2.58% Traditional cash on cash: 6.56% Airbnb Rental Income: $1970 Traditional Rental Income: $2757 Airbnb ROI: 2.58% Traditional ROI: 6.56%
1300 River Valley Road Doniphan, MO Experience refined riverfront living in this exceptional 4 bedroom, 3 bath contemporary ca...	4 beds \| 3 baths \| 1,768 sq.ft.	$625,000	Airbnb cash on cash: 1.11% Traditional cash on cash: 3.3% Airbnb Rental Income: $1970 Traditional Rental Income: $2732 Airbnb ROI: 1.11% Traditional ROI: 3.3%
1457 Riverway Drive Doniphan, MO Escape to modern luxury in this Riverfront cabin retreat! Welcome to your dream getaway- a...	5 beds \| 2 baths \| 2,480 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $2605 Airbnb ROI: N/A Traditional ROI: 3.86%
113 Ripley 142E-17 Doniphan, MO Tucked away just east of Doniphan at the end of a quiet dead-end road, this charming 3-bed...	3 beds \| 2 baths \| 1,444 sq.ft.	$225,900	Airbnb cash on cash: -1.11% Traditional cash on cash: 6.66% Airbnb Rental Income: $413 Traditional Rental Income: $1817 Airbnb ROI: -1.11% Traditional ROI: 6.66%
2225 Us Highway 160 Doniphan, MO Very attractive 3 bedroom, 2 full bath home, new granite counter tops, on 8 ac. m/l, fence...	3 beds \| 2 baths \| 1,280 sq.ft.	$179,000	Airbnb cash on cash: -0.73% Traditional cash on cash: 8.55% Airbnb Rental Income: $413 Traditional Rental Income: $1737 Airbnb ROI: -0.73% Traditional ROI: 8.55%
607 Wanda Road Doniphan, MO This beautifully remodeled 3 bedroom, 2 bath home offers a perfect blend of modern comfort...	3 beds \| 2 baths \| 1,444 sq.ft.	$189,500	Airbnb cash on cash: -0.92% Traditional cash on cash: 6.19% Airbnb Rental Income: $413 Traditional Rental Income: $1436 Airbnb ROI: -0.92% Traditional ROI: 6.19%
1008 Barton Road Doniphan, MO Take a look at this newly remodeled home on the edge of city limits just outside of Doniph...	3 beds \| 3 baths \| 2,324 sq.ft.	$259,500	Airbnb cash on cash: -1.04% Traditional cash on cash: 9.2% Airbnb Rental Income: $413 Traditional Rental Income: $2662 Airbnb ROI: -1.04% Traditional ROI: 9.2%
489 Pumpkin Patch Road Doniphan, MO Escape to your dream country life! This stunning barndominium on 13 +/- acres just outside...	2 beds \| 2 baths \| 3,600 sq.ft.	$550,000	Airbnb cash on cash: -1.47% Traditional cash on cash: 1.86% Airbnb Rental Income: $241 Traditional Rental Income: $1726 Airbnb ROI: -1.47% Traditional ROI: 1.86%
53 Snapping Turtle Lane Doniphan, MO Freshly remodeled three bed, two bath home just east of Doniphan off Brooks Lane. Sitting ...	3 beds \| 2 baths \| 1,374 sq.ft.	$179,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 7.8% Airbnb Rental Income: $413 Traditional Rental Income: $1662 Airbnb ROI: -1.04% Traditional ROI: 7.8%
39 Oxen Pasture Rd Doniphan, MO HOME FOR SALE IN DONIPHAN, MISSOURI WITH DETACHED SHOP Featuring a very modern and...	4 beds \| 3 baths \| 1,700 sq.ft.	$329,000	Airbnb cash on cash: 2.43% Traditional cash on cash: 3.15% Airbnb Rental Income: $1970 Traditional Rental Income: $1673 Airbnb ROI: 2.43% Traditional ROI: 3.15%
2756 Ripley 142E-20 Doniphan, MO Newly remodeled home comes with kitchen appliances, a partially fenced back yard on a leve...	3 beds \| 1 baths \| 1,034 sq.ft.	$119,900	Airbnb cash on cash: -0.75% Traditional cash on cash: 8.95% Airbnb Rental Income: $413 Traditional Rental Income: $1277 Airbnb ROI: -0.75% Traditional ROI: 8.95%
13 Walleye Lane Doniphan, MO Turn-Key 3BR Log Cabin on the Current River - No Flood Risk - Fully FurnishedBeautifully m...	3 beds \| 1 baths \| 1,200 sq.ft.	$444,900	Airbnb cash on cash: -0.93% Traditional cash on cash: 0.88% Airbnb Rental Income: $413 Traditional Rental Income: $910 Airbnb ROI: -0.93% Traditional ROI: 0.88%
243 Big Pine Road Doniphan, MO Escape to the peace and privacy of country living on 3.49 +/- acres surrounded by woods an...	3 beds \| 2 baths \| 1,860 sq.ft.	$339,900	Airbnb cash on cash: -1.13% Traditional cash on cash: 4.07% Airbnb Rental Income: $413 Traditional Rental Income: $1815 Airbnb ROI: -1.13% Traditional ROI: 4.07%
394 Violet Ln Doniphan, MO Welcome to your FULLY FURNISHED, private riverfront paradise on the beautiful Current Rive...	4 beds \| 4 baths \| 3,599 sq.ft.	$1,399,900	Airbnb cash on cash: -0.19% Traditional cash on cash: 1.72% Airbnb Rental Income: $1970 Traditional Rental Income: $3943 Airbnb ROI: -0.19% Traditional ROI: 1.72%
2977 Ripley Route A Doniphan, MO Very attractive 1,800 sq. ft. modular home, with metal roof, built in 2006. This 3 bedroom...	3 beds \| 2 baths \| 1,800 sq.ft.	$224,000	Airbnb cash on cash: -0.92% Traditional cash on cash: 7.75% Airbnb Rental Income: $413 Traditional Rental Income: $1992 Airbnb ROI: -0.92% Traditional ROI: 7.75%
1004 Barton Road Doniphan, MO Check out this really nice affordable home just outside the city limits of Doniphan! This ...	3 beds \| 2 baths \| 2,016 sq.ft.	$189,500	Airbnb cash on cash: -1.06% Traditional cash on cash: 9.56% Airbnb Rental Income: $413 Traditional Rental Income: $2068 Airbnb ROI: -1.06% Traditional ROI: 9.56%
38 Ripley E #U4-B Doniphan, MO Set within a gated community along the famed Current River in Doniphan, The Riverbend Cott...	3 beds \| 2 baths \| 1,456 sq.ft.	$409,000	Airbnb cash on cash: -1.13% Traditional cash on cash: 2.23% Airbnb Rental Income: $413 Traditional Rental Income: $1444 Airbnb ROI: -1.13% Traditional ROI: 2.23%
207 Jackson Street Doniphan, MO Quaint two-bedroom, one-bath home located just minutes from Current River and in city limi...	2 beds \| 1 baths \| 928 sq.ft.	$125,000	Airbnb cash on cash: -1.91% Traditional cash on cash: 7.49% Airbnb Rental Income: $241 Traditional Rental Income: $1144 Airbnb ROI: -1.91% Traditional ROI: 7.49%
201 Ripley E-4 Doniphan, MO This home has been completely renovated from top to bottom-giving you the charm of a river...	3 beds \| 2 baths \| 1,900 sq.ft.	$219,000	Airbnb cash on cash: -1.16% Traditional cash on cash: 8.28% Airbnb Rental Income: $413 Traditional Rental Income: $2113 Airbnb ROI: -1.16% Traditional ROI: 8.28%
220 Ripley 160E-8 Doniphan, MO Welcome home to this charming 3-bedroom, 2.5-bath gem featuring a super cute open floor pl...	3 beds \| 3 baths \| 2,000 sq.ft.	$225,000	Airbnb cash on cash: -1% Traditional cash on cash: 8.09% Airbnb Rental Income: $413 Traditional Rental Income: $2092 Airbnb ROI: -1% Traditional ROI: 8.09%
461 Ripley 142E-24A Doniphan, MO Freshly remodeled home and only a few minutes from Doniphan. Nice 3 bedroom, 1 bath home o...	3 beds \| 1 baths \| 1,034 sq.ft.	$129,900	Airbnb cash on cash: -0.84% Traditional cash on cash: 7.78% Airbnb Rental Income: $413 Traditional Rental Income: $1231 Airbnb ROI: -0.84% Traditional ROI: 7.78%
286 Ripley O-3 Doniphan, MO Completely remodeled four bedroom 2 bath home on 5 acres m/l with beautiful pond views. Th...	4 beds \| 2 baths \| 1,728 sq.ft.	$299,900	Airbnb cash on cash: 3.64% Traditional cash on cash: 5.59% Airbnb Rental Income: $1970 Traditional Rental Income: $2001 Airbnb ROI: 3.64% Traditional ROI: 5.59%
1137 Riverlawn Drive Doniphan, MO Welcome to Patriots Pointâyour private slice of paradise on the Current River. With over...	4 beds \| 2 baths \| 1,560 sq.ft.	$699,900	Airbnb cash on cash: 0.94% Traditional cash on cash: 1.86% Airbnb Rental Income: $1970 Traditional Rental Income: $2056 Airbnb ROI: 0.94% Traditional ROI: 1.86%
509 Plum Street Doniphan, MO Looking for an investment property or a first time home? Freshly remodeled, this is a 1 be...	1 beds \| 1 baths \| 936 sq.ft.	$79,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.54% Airbnb Rental Income: $null Traditional Rental Income: $1021 Airbnb ROI: N/A Traditional ROI: 10.54%
105 Ripley 142E-20F Doniphan, MO Check out this beautiful home just outside of Doniphan!! This home is one of the nicest si...	3 beds \| 2 baths \| 2,278 sq.ft.	$449,900	Airbnb cash on cash: -1.16% Traditional cash on cash: 3.71% Airbnb Rental Income: $413 Traditional Rental Income: $2209 Airbnb ROI: -1.16% Traditional ROI: 3.71%
7687 Ripley Route A Doniphan, MO Country Living With Multi-Generational Potential on 6 Acres Bring your horses, start your ...	4 beds \| 2 baths \| 1,828 sq.ft.	$179,900	Airbnb cash on cash: 6.62% Traditional cash on cash: 10.07% Airbnb Rental Income: $1970 Traditional Rental Income: $2043 Airbnb ROI: 6.62% Traditional ROI: 10.07%
685 State Hwy 142E Doniphan, MO Wow! Pristine, approximately 5600 square feet church building on 1 acre. This property is ...	4 beds \| 3 baths \| 5,600 sq.ft.	$199,900	Airbnb cash on cash: 5.21% Traditional cash on cash: 10.9% Airbnb Rental Income: $1970 Traditional Rental Income: $2533 Airbnb ROI: 5.21% Traditional ROI: 10.9%
2402 Ripley Route A Doniphan, MO Discover this spacious and beautifully designed 3,497 sq ft home nestled on the banks of t...	3 beds \| 3 baths \| 3,497 sq.ft.	$1,250,000	Airbnb cash on cash: -1.08% Traditional cash on cash: 1.16% Airbnb Rental Income: $413 Traditional Rental Income: $2765 Airbnb ROI: -1.08% Traditional ROI: 1.16%
7393 Us Hwy 160 West Doniphan, MO If you have spent hours looking for peace, tranquility, seclusion and privacy and just a s...	5 beds \| 2 baths \| 2,200 sq.ft.	$169,900	Airbnb cash on cash: N/A Traditional cash on cash: 11.95% Airbnb Rental Income: $null Traditional Rental Income: $2231 Airbnb ROI: N/A Traditional ROI: 11.95%
219 Ripley 142E-24B-2 Doniphan, MO Just outside of town this charming residence offers the flexibility of 3-4 bedrooms, along...	4 beds \| 2 baths \| 1,926 sq.ft.	$179,900	Airbnb cash on cash: 6.59% Traditional cash on cash: 10.45% Airbnb Rental Income: $1970 Traditional Rental Income: $2113 Airbnb ROI: 6.59% Traditional ROI: 10.45%

Real Estate investment in Doniphan, MO

There are 44 properties for sale in the city of Doniphan . The median list price in Doniphan is $229,000 and the average price per square foot is $118. In May 2026, the average monthly cash on cash return in Doniphan is 7.00%. The average monthly rental income in Doniphan is $1,997.

Doniphan, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 44 investment properties available for sale in Doniphan.

In 2026, the best neighborhood to buy investment property is Doniphan.

The ROI for Long-Term is higher than the Short-Term in Doniphan with average rental income of $1,997.

Your search for investment property begins and ends here

Investment Property for Sale in Doniphan, MO

4396 State Highway 21

Doniphan, MO

3 beds | 2 baths | 2,064 sq.ft.

$269,900

Airbnb cash on cash: -0.95%

Traditional cash on cash: 6.63%

Airbnb Rental Income: $413

Traditional Rental Income: $2084

Airbnb ROI: -0.95%

Traditional ROI: 6.63%

4795 Ripley K-1

Doniphan, MO

4 beds | 2 baths | 1,800 sq.ft.

$274,999

Airbnb cash on cash: 3.85%

Traditional cash on cash: 5.87%

Airbnb Rental Income: $1970

Traditional Rental Income: $1978

Airbnb ROI: 3.85%

Traditional ROI: 5.87%

1092 Ripley E1-A

Doniphan, MO

5 beds | 5 baths | 4,624 sq.ft.

$649,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.04%

Airbnb Rental Income: $null

Traditional Rental Income: $5163

Airbnb ROI: N/A

Traditional ROI: 7.04%

1901 River Valley Road

Doniphan, MO

3 beds | 3 baths | 1,834 sq.ft.

$674,900

Airbnb cash on cash: -1.19%

Traditional cash on cash: 2.6%

Airbnb Rental Income: $413

Traditional Rental Income: $2540

Airbnb ROI: -1.19%

Traditional ROI: 2.6%

406 Miller Street

Doniphan, MO

3 beds | 1 baths | 1,250 sq.ft.

$150,000

Airbnb cash on cash: -0.96%

Traditional cash on cash: 5.21%

Airbnb Rental Income: $413

Traditional Rental Income: $1042

Airbnb ROI: -0.96%

Traditional ROI: 5.21%

6029 Ripley Rt V

Doniphan, MO

3 beds | 3 baths | 3,067 sq.ft.

$399,000

Airbnb cash on cash: -1.17%

Traditional cash on cash: 5.42%

Airbnb Rental Income: $413

Traditional Rental Income: $2619

Airbnb ROI: -1.17%

Traditional ROI: 5.42%

936 Crawdad Lane

Doniphan, MO

4 beds | 2 baths | 2,997 sq.ft.

$749,900

Airbnb cash on cash: 0.76%

Traditional cash on cash: 2.51%

Airbnb Rental Income: $1970

Traditional Rental Income: $2677

Airbnb ROI: 0.76%

Traditional ROI: 2.51%

1103 Cherry Street

Doniphan, MO

4 beds | 3 baths | 6,280 sq.ft.

$349,000

Airbnb cash on cash: 2.58%

Traditional cash on cash: 6.56%

Airbnb Rental Income: $1970

Traditional Rental Income: $2757

Airbnb ROI: 2.58%