Real Estate Investment Properties for Sale in Doniphan, MO

Looking for investment property in Doniphan, MO with high ROI ?

Explore a variety of short-term homes & houses in Doniphan, MO. Invest wisely with VRBO & Doniphan, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Doniphan, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4396 State Highway 21 Doniphan, MO Remarkable Home within 5 minutes of Doniphan! This 3,(possibly 4) bedroom, 2 bath home on ...	3 beds \| 2 baths \| 2,064 sq.ft.	$279,900	Airbnb cash on cash: -0.76% Traditional cash on cash: 6.36% Airbnb Rental Income: $472 Traditional Rental Income: $2084 Airbnb ROI: -0.76% Traditional ROI: 6.36%
4795 Ripley K-1 Doniphan, MO Built in 2024, this beautiful 4-bedroom, 2-bath home offers modern comfort with a spacious...	4 beds \| 2 baths \| 1,800 sq.ft.	$287,700	Airbnb cash on cash: 3.14% Traditional cash on cash: 5.57% Airbnb Rental Income: $1808 Traditional Rental Income: $1978 Airbnb ROI: 3.14% Traditional ROI: 5.57%
1901 River Valley Road Doniphan, MO CURRENT RIVER CABIN â RIVERFRONT, 2 ACRES, MINUTES FROM DONIPHAN Experience the beauty ...	3 beds \| 3 baths \| 1,834 sq.ft.	$685,000	Airbnb cash on cash: -1.11% Traditional cash on cash: 2.54% Airbnb Rental Income: $472 Traditional Rental Income: $2540 Airbnb ROI: -1.11% Traditional ROI: 2.54%
101 Walnut Street Doniphan, MO Check out this charming and updated home right in Doniphan! This spacious 2 bedroom, 1 bat...	2 beds \| 1 baths \| 1,289 sq.ft.	$69,900	Airbnb cash on cash: -1.59% Traditional cash on cash: 9.09% Airbnb Rental Income: $314 Traditional Rental Income: $814 Airbnb ROI: -1.59% Traditional ROI: 9.09%
936 Crawdad Lane Doniphan, MO Private 75-Acre Estate with Lake, 3 Homes & borders Government Forest . A private Lakefro...	4 beds \| 2 baths \| 2,997 sq.ft.	$749,900	Airbnb cash on cash: 0.56% Traditional cash on cash: 2.51% Airbnb Rental Income: $1808 Traditional Rental Income: $2677 Airbnb ROI: 0.56% Traditional ROI: 2.51%
1103 Cherry Street Doniphan, MO This is the listing that everyone will be talking about. It's a Doniphan landmark. Sitting...	4 beds \| 3 baths \| 6,280 sq.ft.	$399,000	Airbnb cash on cash: 1.77% Traditional cash on cash: 5.62% Airbnb Rental Income: $1808 Traditional Rental Income: $2757 Airbnb ROI: 1.77% Traditional ROI: 5.62%
1300 River Valley Road Doniphan, MO Experience refined riverfront living in this exceptional 4 bedroom, 3 bath contemporary ca...	4 beds \| 3 baths \| 1,768 sq.ft.	$649,900	Airbnb cash on cash: 0.8% Traditional cash on cash: 3.14% Airbnb Rental Income: $1808 Traditional Rental Income: $2732 Airbnb ROI: 0.8% Traditional ROI: 3.14%
1457 Riverway Drive Doniphan, MO Escape to modern luxury in this Riverfront cabin retreat! Welcome to your dream getaway- a...	5 beds \| 2 baths \| 2,480 sq.ft.	$525,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $2605 Airbnb ROI: N/A Traditional ROI: 3.86%
2402 Ripley Route A Doniphan, MO Discover this spacious and beautifully designed 3,497 sq ft home nestled on the banks of t...	3 beds \| 3 baths \| 3,497 sq.ft.	$1,250,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 1.16% Airbnb Rental Income: $472 Traditional Rental Income: $2765 Airbnb ROI: -1.04% Traditional ROI: 1.16%
8858 State Hwy 142W Doniphan, MO Welcome to your private escape, tucked away at the end of a beautiful, wooded driveway. S...	3 beds \| 2 baths \| 1,282 sq.ft.	$250,000	Airbnb cash on cash: -0.82% Traditional cash on cash: 5.28% Airbnb Rental Income: $472 Traditional Rental Income: $1645 Airbnb ROI: -0.82% Traditional ROI: 5.28%
4375 State Highway 142 east Doniphan, MO Charming 3 Bedroom Brick Home Near Current River! Looking for peaceful country living j...	3 beds \| 2 baths \| 1,956 sq.ft.	$219,900	Airbnb cash on cash: -0.79% Traditional cash on cash: 8.58% Airbnb Rental Income: $472 Traditional Rental Income: $2156 Airbnb ROI: -0.79% Traditional ROI: 8.58%
1009 Ripley 21N-6 Doniphan, MO Welcome to peaceful country living! This charming 1.5-story home sits on 3 wooded acres M/...	3 beds \| 1 baths \| 1,140 sq.ft.	$119,900	Airbnb cash on cash: -0.1% Traditional cash on cash: 10.19% Airbnb Rental Income: $472 Traditional Rental Income: $1395 Airbnb ROI: -0.1% Traditional ROI: 10.19%
1008 Barton Road Doniphan, MO Take a look at this newly remodeled home on the edge of city limits just outside of Doniph...	3 beds \| 3 baths \| 2,324 sq.ft.	$279,500	Airbnb cash on cash: -0.85% Traditional cash on cash: 8.48% Airbnb Rental Income: $472 Traditional Rental Income: $2662 Airbnb ROI: -0.85% Traditional ROI: 8.48%
285 Ripley Z-4 Doniphan, MO Check out this awesome 84 acre +/- property with a home, barn, shop, pond and extra well o...	3 beds \| 1 baths \| 1,160 sq.ft.	$389,500	Airbnb cash on cash: -0.8% Traditional cash on cash: 2.89% Airbnb Rental Income: $472 Traditional Rental Income: $1551 Airbnb ROI: -0.8% Traditional ROI: 2.89%
489 Pumpkin Patch Road Doniphan, MO Escape to your dream country life! This stunning barndominium on 13 +/- acres just outside...	2 beds \| 2 baths \| 3,600 sq.ft.	$550,000	Airbnb cash on cash: -1.35% Traditional cash on cash: 1.86% Airbnb Rental Income: $314 Traditional Rental Income: $1726 Airbnb ROI: -1.35% Traditional ROI: 1.86%
53 Snapping Turtle Lane Doniphan, MO Freshly remodeled three bed, two bath home just east of Doniphan off Brooks Lane. Sitting ...	3 beds \| 2 baths \| 1,374 sq.ft.	$179,000	Airbnb cash on cash: -0.75% Traditional cash on cash: 7.8% Airbnb Rental Income: $472 Traditional Rental Income: $1662 Airbnb ROI: -0.75% Traditional ROI: 7.8%
39 Oxen Pasture Rd Doniphan, MO HOME FOR SALE IN DONIPHAN, MISSOURI WITH DETACHED SHOP Featuring a very modern and...	4 beds \| 3 baths \| 1,700 sq.ft.	$329,000	Airbnb cash on cash: 2% Traditional cash on cash: 3.15% Airbnb Rental Income: $1808 Traditional Rental Income: $1673 Airbnb ROI: 2% Traditional ROI: 3.15%
236 Ripley 21n-16b Doniphan, MO Tucked away on 1.8 acres on the outskirts of Doniphan, this classic ranch-style home offer...	3 beds \| 2 baths \| 1,732 sq.ft.	$250,000	Airbnb cash on cash: -0.93% Traditional cash on cash: 4.66% Airbnb Rental Income: $472 Traditional Rental Income: $1523 Airbnb ROI: -0.93% Traditional ROI: 4.66%
2756 Ripley 142E-20 Doniphan, MO Newly remodeled home comes with kitchen appliances, a partially fenced back yard on a leve...	3 beds \| 1 baths \| 1,034 sq.ft.	$129,900	Airbnb cash on cash: -0.37% Traditional cash on cash: 8.22% Airbnb Rental Income: $472 Traditional Rental Income: $1277 Airbnb ROI: -0.37% Traditional ROI: 8.22%
243 Big Pine Road Doniphan, MO Escape to the peace and privacy of country living on 3.49 +/- acres surrounded by woods an...	3 beds \| 2 baths \| 1,860 sq.ft.	$350,000	Airbnb cash on cash: -0.98% Traditional cash on cash: 3.92% Airbnb Rental Income: $472 Traditional Rental Income: $1815 Airbnb ROI: -0.98% Traditional ROI: 3.92%
394 Violet Ln Doniphan, MO Welcome to your FULLY FURNISHED, private riverfront paradise on the beautiful Current Rive...	4 beds \| 4 baths \| 3,599 sq.ft.	$1,399,900	Airbnb cash on cash: -0.3% Traditional cash on cash: 1.72% Airbnb Rental Income: $1808 Traditional Rental Income: $3943 Airbnb ROI: -0.3% Traditional ROI: 1.72%
8 Summerfield Estates Doniphan, MO Check out this beautiful 3 bed (could be 4), 2 bath home in the desirable Summerfield Esta...	3 beds \| 2 baths \| 1,960 sq.ft.	$229,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 8.33% Airbnb Rental Income: $472 Traditional Rental Income: $2235 Airbnb ROI: -1.04% Traditional ROI: 8.33%
2977 Ripley Route A Doniphan, MO Very attractive 1,800 sq. ft. modular home, with metal roof, built in 2006. This 3 bedroom...	3 beds \| 2 baths \| 1,800 sq.ft.	$229,000	Airbnb cash on cash: -0.69% Traditional cash on cash: 7.56% Airbnb Rental Income: $472 Traditional Rental Income: $1992 Airbnb ROI: -0.69% Traditional ROI: 7.56%
1004 Barton Road Doniphan, MO Check out this really nice affordable home just outside the city limits of Doniphan! This ...	3 beds \| 2 baths \| 2,016 sq.ft.	$199,900	Airbnb cash on cash: -0.8% Traditional cash on cash: 9.02% Airbnb Rental Income: $472 Traditional Rental Income: $2068 Airbnb ROI: -0.8% Traditional ROI: 9.02%
7393 Us Hwy 160 West Doniphan, MO If you have spent hours looking for peace, tranquility, seclusion and privacy and just a s...	5 beds \| 2 baths \| 2,200 sq.ft.	$169,900	Airbnb cash on cash: N/A Traditional cash on cash: 11.95% Airbnb Rental Income: $null Traditional Rental Income: $2231 Airbnb ROI: N/A Traditional ROI: 11.95%
219 Ripley 142E-24B-2 Doniphan, MO Just outside of town this charming residence offers the flexibility of 3-4 bedrooms, along...	4 beds \| 2 baths \| 1,926 sq.ft.	$179,900	Airbnb cash on cash: 5.8% Traditional cash on cash: 10.45% Airbnb Rental Income: $1808 Traditional Rental Income: $2113 Airbnb ROI: 5.8% Traditional ROI: 10.45%
207 Jackson Street Doniphan, MO Quaint two-bedroom, one-bath home located just minutes from Current River and in city limi...	2 beds \| 1 baths \| 928 sq.ft.	$125,000	Airbnb cash on cash: -1.4% Traditional cash on cash: 7.49% Airbnb Rental Income: $314 Traditional Rental Income: $1144 Airbnb ROI: -1.4% Traditional ROI: 7.49%
201 Ripley E-4 Doniphan, MO This home has been completely renovated from top to bottom-giving you the charm of a river...	3 beds \| 2 baths \| 1,900 sq.ft.	$225,000	Airbnb cash on cash: -0.92% Traditional cash on cash: 8.04% Airbnb Rental Income: $472 Traditional Rental Income: $2113 Airbnb ROI: -0.92% Traditional ROI: 8.04%
1305 State Highway 142 E Doniphan, MO Look at this location. This all brick 4 bedroom, 2 bath home located just past the new Dol...	4 beds \| 2 baths \| 2,804 sq.ft.	$229,000	Airbnb cash on cash: 3.69% Traditional cash on cash: 8.74% Airbnb Rental Income: $1808 Traditional Rental Income: $2412 Airbnb ROI: 3.69% Traditional ROI: 8.74%
220 Ripley 160E-8 Doniphan, MO Welcome home to this charming 3-bedroom, 2.5-bath gem featuring a super cute open floor pl...	3 beds \| 3 baths \| 2,000 sq.ft.	$229,900	Airbnb cash on cash: -0.77% Traditional cash on cash: 7.9% Airbnb Rental Income: $472 Traditional Rental Income: $2092 Airbnb ROI: -0.77% Traditional ROI: 7.9%
464 Ripley 21S-1 Doniphan, MO Check out this super nice freshly remodeled 4 bed 3 bath home outside of Doniphan! This ho...	4 beds \| 3 baths \| 2,040 sq.ft.	$249,500	Airbnb cash on cash: 3.95% Traditional cash on cash: 9.56% Airbnb Rental Income: $1808 Traditional Rental Income: $2639 Airbnb ROI: 3.95% Traditional ROI: 9.56%
115 Snapping Turtle Lane Doniphan, MO This 3 bed 2 bath home is conveniently located just outside of Doniphan off of Brooks Lane...	3 beds \| 2 baths \| 1,818 sq.ft.	$235,000	Airbnb cash on cash: -0.91% Traditional cash on cash: 3.75% Airbnb Rental Income: $472 Traditional Rental Income: $1240 Airbnb ROI: -0.91% Traditional ROI: 3.75%
1369 Ripley 142E-16 Doniphan, MO Nice location and house with lots of potential. Vinyl sided home with covered front porch,...	3 beds \| 1 baths \| 912 sq.ft.	$89,900	Airbnb cash on cash: -0.11% Traditional cash on cash: 10.62% Airbnb Rental Income: $472 Traditional Rental Income: $1147 Airbnb ROI: -0.11% Traditional ROI: 10.62%
104 S Green Street Doniphan, MO Beautiful, remodeled large 4 bedroom/ 2 bath home in the city limits of Doniphan. Many up...	4 beds \| 2 baths \| 1,534 sq.ft.	$219,900	Airbnb cash on cash: 4.51% Traditional cash on cash: 8.69% Airbnb Rental Income: $1808 Traditional Rental Income: $2188 Airbnb ROI: 4.51% Traditional ROI: 8.69%
404 N Lafayette Street Doniphan, MO This once was probably one of Doniphan's nicest homes. It has now been restored to make it...	5 beds \| 3 baths \| 3,045 sq.ft.	$229,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.6% Airbnb Rental Income: $null Traditional Rental Income: $2916 Airbnb ROI: N/A Traditional ROI: 11.6%
175 Hodge Drive Doniphan, MO Check out this super nice, secluded and cute 1 bed, 1 bath home on 3 +/- acres! This home ...	1 beds \| 1 baths \| 864 sq.ft.	$129,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.94% Airbnb Rental Income: $null Traditional Rental Income: $1258 Airbnb ROI: N/A Traditional ROI: 7.94%
167 Ripley Y-3 Doniphan, MO Check out this beautiful 3 bed, 2 bath on 12.5 +/- acres that backs up to government groun...	3 beds \| 2 baths \| 1,624 sq.ft.	$239,900	Airbnb cash on cash: -0.69% Traditional cash on cash: 6.11% Airbnb Rental Income: $472 Traditional Rental Income: $1747 Airbnb ROI: -0.69% Traditional ROI: 6.11%

Real Estate investment in Doniphan, MO

There are 41 properties for sale in the city of Doniphan . The median list price in Doniphan is $235,450 and the average price per square foot is $123. In April 2026, the average monthly cash on cash return in Doniphan is 8.00%. The average monthly rental income in Doniphan is $2,076.

Doniphan, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 41 investment properties available for sale in Doniphan.

In 2026, the best neighborhood to buy investment property is Doniphan.

The ROI for Long-Term is higher than the Short-Term in Doniphan with average rental income of $2,076.

Your search for investment property begins and ends here

Investment Property for Sale in Doniphan, MO

4396 State Highway 21

Doniphan, MO

3 beds | 2 baths | 2,064 sq.ft.

$279,900

Airbnb cash on cash: -0.76%

Traditional cash on cash: 6.36%

Airbnb Rental Income: $472

Traditional Rental Income: $2084

Airbnb ROI: -0.76%

Traditional ROI: 6.36%

4795 Ripley K-1

Doniphan, MO

4 beds | 2 baths | 1,800 sq.ft.

$287,700

Airbnb cash on cash: 3.14%

Traditional cash on cash: 5.57%

Airbnb Rental Income: $1808

Traditional Rental Income: $1978

Airbnb ROI: 3.14%

Traditional ROI: 5.57%

1901 River Valley Road

Doniphan, MO

3 beds | 3 baths | 1,834 sq.ft.

$685,000

Airbnb cash on cash: -1.11%

Traditional cash on cash: 2.54%

Airbnb Rental Income: $472

Traditional Rental Income: $2540

Airbnb ROI: -1.11%

Traditional ROI: 2.54%

101 Walnut Street

Doniphan, MO

2 beds | 1 baths | 1,289 sq.ft.

$69,900

Airbnb cash on cash: -1.59%

Traditional cash on cash: 9.09%

Airbnb Rental Income: $314

Traditional Rental Income: $814

Airbnb ROI: -1.59%

Traditional ROI: 9.09%

936 Crawdad Lane

Doniphan, MO

4 beds | 2 baths | 2,997 sq.ft.

$749,900

Airbnb cash on cash: 0.56%

Traditional cash on cash: 2.51%

Airbnb Rental Income: $1808

Traditional Rental Income: $2677

Airbnb ROI: 0.56%

Traditional ROI: 2.51%

1103 Cherry Street

Doniphan, MO

4 beds | 3 baths | 6,280 sq.ft.

$399,000

Airbnb cash on cash: 1.77%

Traditional cash on cash: 5.62%

Airbnb Rental Income: $1808

Traditional Rental Income: $2757

Airbnb ROI: 1.77%

Traditional ROI: 5.62%

1300 River Valley Road

Doniphan, MO

4 beds | 3 baths | 1,768 sq.ft.

$649,900

Airbnb cash on cash: 0.8%

Traditional cash on cash: 3.14%

Airbnb Rental Income: $1808

Traditional Rental Income: $2732

Airbnb ROI: 0.8%

Traditional ROI: 3.14%

1457 Riverway Drive

Doniphan, MO

5 beds | 2 baths | 2,480 sq.ft.

$525,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.86%

Airbnb Rental Income: $null

Traditional Rental Income: $2605

Airbnb ROI: N/A