Real Estate Investment Properties for Sale in Perryville, MO

Looking for investment property in Perryville, MO with high ROI ?

Explore a variety of short-term homes & houses in Perryville, MO. Invest wisely with VRBO & Perryville, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Perryville, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
13 Pcr 351 Perryville, MO Discover unmatched craftsmanship & comfort in this custom full-brick ranch, offering over ...	4 beds \| 3 baths \| 6,069 sq.ft.	$778,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.39% Airbnb Rental Income: $null Traditional Rental Income: $2189 Airbnb ROI: N/A Traditional ROI: 1.39%
1001 Harry Avenue Perryville, MO MOTIVATED SELLER! Located in a great location, sitting on a corner lot! This brick/vinyl r...	3 beds \| 4 baths \| 2,998 sq.ft.	$354,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.61% Airbnb Rental Income: $null Traditional Rental Income: $2815 Airbnb ROI: N/A Traditional ROI: 6.61%
1034 Port Perry Drive Perryville, MO MOTIVATED SELLER. In Lake Perry you will find up dated ranch home built with quality & car...	3 beds \| 3 baths \| 2,363 sq.ft.	$288,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.73% Airbnb Rental Income: $null Traditional Rental Income: $2399 Airbnb ROI: N/A Traditional ROI: 6.73%
520 Christopher Drive Perryville, MO This impressive lakefront home is located at Twin Lakes, a quaint, private lake community,...	3 beds \| 2 baths \| 2,413 sq.ft.	$385,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.42% Airbnb Rental Income: $null Traditional Rental Income: $2602 Airbnb ROI: N/A Traditional ROI: 5.42%
1665 Redbud Court Perryville, MO This 2 Story well maintained home was built in 2021 and is located in Perryville's newest ...	4 beds \| 3 baths \| 2,368 sq.ft.	$419,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.49% Airbnb Rental Income: $null Traditional Rental Income: $2483 Airbnb ROI: N/A Traditional ROI: 4.49%
118 W Saint Joseph Street Perryville, MO This beautifully remodeled 3-story brick building, originally built in 1900, seamlessly bl...	6 beds \| 4 baths \| 2,798 sq.ft.	$319,000	Airbnb cash on cash: -0.45% Traditional cash on cash: 3.68% Airbnb Rental Income: $885 Traditional Rental Income: $1787 Airbnb ROI: -0.45% Traditional ROI: 3.68%
1026 Hume Street Perryville, MO Adorable 3-bed 2 bath ranch with full basement available for well under appraised value. H...	3 beds \| 2 baths \| 1,050 sq.ft.	$169,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.43% Airbnb Rental Income: $null Traditional Rental Income: $1573 Airbnb ROI: N/A Traditional ROI: 7.43%
221 N Walnut Perryville, MO Step into the perfect blend of historic charm and modern convenience with this beautifully...	4 beds \| 4 baths \| 2,412 sq.ft.	$284,900	Airbnb cash on cash: 0.23% Traditional cash on cash: 3.73% Airbnb Rental Income: $885 Traditional Rental Income: $1488 Airbnb ROI: 0.23% Traditional ROI: 3.73%
1280 PCR 862 Perryville, MO Talk about seclusion! At the end of a dead-end county road discover your private homestead...	4 beds \| 2 baths \| 1,904 sq.ft.	$372,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.3% Airbnb Rental Income: $null Traditional Rental Income: $2410 Airbnb ROI: N/A Traditional ROI: 5.3%
1841 N Main Street Perryville, MO Are you searching for a stately all-Brick estate on 11.43 acres with luxurious amenities a...	4 beds \| 6 baths \| 5,886 sq.ft.	$1,550,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.98% Airbnb Rental Income: $null Traditional Rental Income: $6268 Airbnb ROI: N/A Traditional ROI: 2.98%
997 PCR 914 Perryville, MO Nestled on 2.42 peaceful acres, this charming 1,620 sq. ft. country retreat is ready to we...	2 beds \| 2 baths \| 1,620 sq.ft.	$305,000	Airbnb cash on cash: 0.85% Traditional cash on cash: 5.52% Airbnb Rental Income: $1104 Traditional Rental Income: $2070 Airbnb ROI: 0.85% Traditional ROI: 5.52%
8135 Highway J Perryville, MO Modern Farmhouse on 30.5 Acres â This 3,800 +/- sq. ft. two-level home offers 3 bedrooms...	3 beds \| 3 baths \| 3,800 sq.ft.	$850,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.12% Airbnb Rental Income: $null Traditional Rental Income: $2869 Airbnb ROI: N/A Traditional ROI: 1.12%
2287 Highway Perryville, MO All-brick ranch-style home just minutes from Perryville city limits, offering approximatel...	3 beds \| 2 baths \| 3,720 sq.ft.	$324,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.01% Airbnb Rental Income: $null Traditional Rental Income: $1791 Airbnb ROI: N/A Traditional ROI: 4.01%

Real Estate investment in Perryville, MO

There are 17 properties for sale in the city of Perryville . The median list price in Perryville is $354,900 and the average price per square foot is $126. In October 2025, the average monthly cash on cash return in Perryville is 5.00%. The average monthly rental income in Perryville is $2,302.

Perryville, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 17 investment properties available for sale in Perryville.

In 2025, the best neighborhood to buy investment property is Perryville.

The ROI for Short-Term is higher than the Long-Term in Perryville with average rental income of $885.

Your search for investment property begins and ends here

Investment Property for Sale in Perryville, MO

13 Pcr 351

Perryville, MO

4 beds | 3 baths | 6,069 sq.ft.

$778,000

Airbnb cash on cash: N/A

Traditional cash on cash: 1.39%

Airbnb Rental Income: $null

Traditional Rental Income: $2189

Airbnb ROI: N/A

Traditional ROI: 1.39%

1001 Harry Avenue

Perryville, MO

3 beds | 4 baths | 2,998 sq.ft.

$354,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.61%

Airbnb Rental Income: $null

Traditional Rental Income: $2815

Airbnb ROI: N/A

Traditional ROI: 6.61%

1034 Port Perry Drive

Perryville, MO

3 beds | 3 baths | 2,363 sq.ft.

$288,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.73%

Airbnb Rental Income: $null

Traditional Rental Income: $2399

Airbnb ROI: N/A

Traditional ROI: 6.73%

520 Christopher Drive

Perryville, MO

3 beds | 2 baths | 2,413 sq.ft.

$385,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.42%

Airbnb Rental Income: $null

Traditional Rental Income: $2602

Airbnb ROI: N/A

Traditional ROI: 5.42%

1665 Redbud Court

Perryville, MO

4 beds | 3 baths | 2,368 sq.ft.

$419,500

Airbnb cash on cash: N/A

Traditional cash on cash: 4.49%

Airbnb Rental Income: $null

Traditional Rental Income: $2483

Airbnb ROI: N/A

Traditional ROI: 4.49%

118 W Saint Joseph Street

Perryville, MO

6 beds | 4 baths | 2,798 sq.ft.

$319,000

Airbnb cash on cash: -0.45%

Traditional cash on cash: 3.68%

Airbnb Rental Income: $885

Traditional Rental Income: $1787

Airbnb ROI: -0.45%

Traditional ROI: 3.68%

1026 Hume Street

Perryville, MO

3 beds | 2 baths | 1,050 sq.ft.

$169,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.43%

Airbnb Rental Income: $null

Traditional Rental Income: $1573

Airbnb ROI: N/A

Traditional ROI: 7.43%

221 N Walnut

Perryville, MO

4 beds | 4 baths | 2,412 sq.ft.

$284,900

Airbnb cash on cash: 0.23%

Traditional cash on cash: 3.73%

Airbnb Rental Income: $885

Traditional Rental Income: $1488

Airbnb ROI: 0.23%