Real Estate Investment Properties for Sale in Perryville, MO

Looking for investment property in Perryville, MO with high ROI ?

Explore a variety of short-term homes & houses in Perryville, MO. Invest wisely with VRBO & Perryville, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Perryville, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2979 Pcr 501 Perryville, MO This completely remodeled ranch style home offers 3 bedrooms and 1 full ball. The home fea...	3 beds \| 1 baths \| 960 sq.ft.	$130,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.92% Airbnb Rental Income: $null Traditional Rental Income: $1022 Airbnb ROI: N/A Traditional ROI: 5.92%
44 Hopi Ln Perryville, MO Looking for a home on lake property? Wait no more - this is the perfect home! Itâs sim...	2 beds \| 1 baths \| 840 sq.ft.	$159,000	Airbnb cash on cash: 0.49% Traditional cash on cash: 3.32% Airbnb Rental Income: $719 Traditional Rental Income: $840 Airbnb ROI: 0.49% Traditional ROI: 3.32%
1606 Old Saint Marys Rd Perryville, MO Check out this charming 4 bedroom, 1 bath home conveniently located near all of the amenit...	4 beds \| 1 baths \| 1,215 sq.ft.	$215,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.52% Airbnb Rental Income: $null Traditional Rental Income: $1501 Airbnb ROI: N/A Traditional ROI: 5.52%
815 Ridge Dr Perryville, MO If you've been looking for a beautiful home in a great location, your search is over. Thi...	3 beds \| 3 baths \| 3,564 sq.ft.	$295,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.86% Airbnb Rental Income: $null Traditional Rental Income: $1872 Airbnb ROI: N/A Traditional ROI: 4.86%
114 Edwards St Perryville, MO This adorable 3 bed, 1 Â½ bath home in Perryville is a rare find! This Ranch Style home of...	3 beds \| 1 baths \| 1,064 sq.ft.	$109,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.61% Airbnb Rental Income: $null Traditional Rental Income: $1203 Airbnb ROI: N/A Traditional ROI: 8.61%
1240 Drury Ln Perryville, MO Located within very short walking distance of the soccer park, it is in a prime location, ...	3 beds \| 2 baths \| 1,955 sq.ft.	$284,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.08% Airbnb Rental Income: $null Traditional Rental Income: $2150 Airbnb ROI: N/A Traditional ROI: 6.08%
2759 Pcr 910 Perryville, MO Many possibilities with this exceptional farm in Perry County. Fenced for cattle, excellen...	3 beds \| 2 baths \| 2,208 sq.ft.	$1,498,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.42% Airbnb Rental Income: $null Traditional Rental Income: $2175 Airbnb ROI: N/A Traditional ROI: 0.42%
814 Star St Perryville, MO This beautiful and affordable home is close to all Perryville has to offer! With 2 beds, 1...	2 beds \| 1 baths \| 940 sq.ft.	$158,900	Airbnb cash on cash: 0.56% Traditional cash on cash: 5.57% Airbnb Rental Income: $719 Traditional Rental Income: $1171 Airbnb ROI: 0.56% Traditional ROI: 5.57%
13 Pcr 351 Perryville, MO Discover unmatched craftsmanship & comfort in this custom full-brick ranch, offering over ...	4 beds \| 3 baths \| 6,069 sq.ft.	$665,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.79% Airbnb Rental Income: $null Traditional Rental Income: $2189 Airbnb ROI: N/A Traditional ROI: 1.79%
520 Christopher Dr Perryville, MO This stunning lakefront retreat at Twin Lakes offers the perfect blend of comfort, charm, ...	4 beds \| 2 baths \| 2,413 sq.ft.	$365,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.64% Airbnb Rental Income: $null Traditional Rental Income: $2602 Airbnb ROI: N/A Traditional ROI: 5.64%
1128 W North St Perryville, MO New Listing! This charming home, located at 1128 W North St. in Perryville, MO, offers 1,2...	3 beds \| 1 baths \| 1,218 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.05% Airbnb Rental Income: $null Traditional Rental Income: $1454 Airbnb ROI: N/A Traditional ROI: 6.05%
1841 N Main St Perryville, MO Are you searching for a stately all-Brick estate on 11.43 acres with luxurious amenities a...	4 beds \| 5 baths \| 5,886 sq.ft.	$1,395,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.42% Airbnb Rental Income: $null Traditional Rental Income: $6268 Airbnb ROI: N/A Traditional ROI: 3.42%
1002 Port Perry Dr Perryville, MO 1002 Port Perry Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$52,500	Airbnb cash on cash: -6.39% Traditional cash on cash: 8.14% Airbnb Rental Income: $167 Traditional Rental Income: $724 Airbnb ROI: -6.39% Traditional ROI: 8.14%
1 Perryville Blvd Perryville, MO 1 Perryville Blvd, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$607,464	Airbnb cash on cash: -2.21% Traditional cash on cash: -0.85% Airbnb Rental Income: $167 Traditional Rental Income: $724 Airbnb ROI: -2.21% Traditional ROI: -0.85%
1038 W Saint Joseph St Perryville, MO 1038 W Saint Joseph St, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,496 sq.ft.	$222,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.04% Airbnb Rental Income: $null Traditional Rental Income: $1143 Airbnb ROI: N/A Traditional ROI: 3.04%
221 W Saint Joseph St Perryville, MO 221 W Saint Joseph St, Perryville, MO 63775 \| Single Family Residential	6 beds \| 4 baths \| 3,143 sq.ft.	$560,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.67% Airbnb Rental Income: $null Traditional Rental Income: $3565 Airbnb ROI: N/A Traditional ROI: 4.67%
456 Pcr 740 Perryville, MO 456 Pcr 740, Perryville, MO 63775 \| Single Family Residential	N/A beds \| N/A baths \| 0 sq.ft.	$150,000	Airbnb cash on cash: -2.95% Traditional cash on cash: 3.57% Airbnb Rental Income: $167 Traditional Rental Income: $886 Airbnb ROI: -2.95% Traditional ROI: 3.57%
10289 Highway J Perryville, MO 10289 Highway J, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,672 sq.ft.	$350,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.54% Airbnb Rental Income: $null Traditional Rental Income: $1572 Airbnb ROI: N/A Traditional ROI: 2.54%
1744 Pcr 710 Perryville, MO 1744 Pcr 710, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$220,000	Airbnb cash on cash: -2.65% Traditional cash on cash: 1.4% Airbnb Rental Income: $167 Traditional Rental Income: $793 Airbnb ROI: -2.65% Traditional ROI: 1.4%
5137 N View Dr Perryville, MO 5137 N View Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| 0 sq.ft.	$160,000	Airbnb cash on cash: -3.51% Traditional cash on cash: 3.04% Airbnb Rental Income: $167 Traditional Rental Income: $951 Airbnb ROI: -3.51% Traditional ROI: 3.04%
1512 Old St Mary's Rd Perryville, MO 1512 Old St Mary's Rd, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,727 sq.ft.	$555,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.93% Airbnb Rental Income: $null Traditional Rental Income: $1593 Airbnb ROI: N/A Traditional ROI: 0.93%
Off Pcr 210 Perryville, MO Off Pcr 210, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$2,257,500	Airbnb cash on cash: -2.03% Traditional cash on cash: -1.63% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -2.03% Traditional ROI: -1.63%
25 Tyler Br Perryville, MO 25 Tyler Br, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$50,000	Airbnb cash on cash: -5.28% Traditional cash on cash: 11.46% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -5.28% Traditional ROI: 11.46%
1 Cinque Hommes Dr Perryville, MO 1 Cinque Hommes Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$225,000	Airbnb cash on cash: -2.63% Traditional cash on cash: 1.37% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -2.63% Traditional ROI: 1.37%
0 Highway 51 Perryville, MO 0 Highway 51, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$540,330	Airbnb cash on cash: -2.25% Traditional cash on cash: -0.56% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -2.25% Traditional ROI: -0.56%
34 Missouri Ln Perryville, MO Located just outside the city limits of Perryville, this all-brick 3 bedroom, 2 bath home ...	3 beds \| 2 baths \| 2,290 sq.ft.	$424,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.86% Airbnb Rental Income: $null Traditional Rental Income: $2198 Airbnb ROI: N/A Traditional ROI: 3.86%
5031 Port Perry Dr Perryville, MO 5031 Port Perry Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$52,000	Airbnb cash on cash: -6.27% Traditional cash on cash: 9.89% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -6.27% Traditional ROI: 9.89%
Lot #8 Pcr 910 Perryville, MO Lot #8 Pcr 910, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$105,000	Airbnb cash on cash: -3.36% Traditional cash on cash: 5.29% Airbnb Rental Income: $167 Traditional Rental Income: $831 Airbnb ROI: -3.36% Traditional ROI: 5.29%
1203 E Lake Dr Perryville, MO	3 beds \| 2 baths \| 960 sq.ft.	$120,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.06% Airbnb Rental Income: $null Traditional Rental Income: $1137 Airbnb ROI: N/A Traditional ROI: 7.06%
700 Feltz St Perryville, MO 700 Feltz St, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,812 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.55% Airbnb Rental Income: $null Traditional Rental Income: $1644 Airbnb ROI: N/A Traditional ROI: 3.55%
7633 Highway F Perryville, MO This isn't just a home, it's a lifestyle. Nestled on 3.13 acres in Perry County, this cust...	3 beds \| 2 baths \| 2,932 sq.ft.	$688,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.75% Airbnb Rental Income: $null Traditional Rental Income: $2118 Airbnb ROI: N/A Traditional ROI: 1.75%
24 S Walnut St Perryville, MO Step into timeless charm with this stunning story-and-half Victorian home located in the h...	4 beds \| 2 baths \| 2,180 sq.ft.	$172,700	Airbnb cash on cash: N/A Traditional cash on cash: 11.75% Airbnb Rental Income: $null Traditional Rental Income: $2313 Airbnb ROI: N/A Traditional ROI: 11.75%
97 Pcr 522 Perryville, MO 97 Pcr 522, Perryville, MO 63775 \| Single Family Residential	5 beds \| 3 baths \| 3,090 sq.ft.	$579,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.16% Airbnb Rental Income: $null Traditional Rental Income: $2324 Airbnb ROI: N/A Traditional ROI: 2.16%
2898 Pcr 856 Perryville, MO 4 Major Highlights: - 4.44 Acre Lot in Lake Perry Farms and part of the Lake Perry Communi...	4 beds \| 2 baths \| 2,828 sq.ft.	$249,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.56% Airbnb Rental Income: $null Traditional Rental Income: $2598 Airbnb ROI: N/A Traditional ROI: 8.56%
697 Parkers Lake Dr Perryville, MO 697 Parkers Lake Dr, Perryville, MO 63775 \| Single Family Residential	2 beds \| 1 baths \| 900 sq.ft.	$129,900	Airbnb cash on cash: 0.58% Traditional cash on cash: 3.74% Airbnb Rental Income: $719 Traditional Rental Income: $805 Airbnb ROI: 0.58% Traditional ROI: 3.74%
1036 Erie Trail Dr Perryville, MO 1036 Erie Trail Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$79,900	Airbnb cash on cash: -4.97% Traditional cash on cash: 6.23% Airbnb Rental Income: $167 Traditional Rental Income: $831 Airbnb ROI: -4.97% Traditional ROI: 6.23%
Lot 6 Dreamz Estate Dr Perryville, MO Lot 6 Dreamz Estate Dr, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$64,900	Airbnb cash on cash: -4.58% Traditional cash on cash: 8.6% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -4.58% Traditional ROI: 8.6%
Lot #7 Pcr 910 Perryville, MO Lot #7 Pcr 910, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$75,000	Airbnb cash on cash: -3.88% Traditional cash on cash: 7.63% Airbnb Rental Income: $167 Traditional Rental Income: $803 Airbnb ROI: -3.88% Traditional ROI: 7.63%
16482 Highway T Perryville, MO 16482 Highway T, Perryville, MO 63775 \| Single Family Residential	3 beds \| 2 baths \| 1,848 sq.ft.	$275,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.96% Airbnb Rental Income: $null Traditional Rental Income: $1627 Airbnb ROI: N/A Traditional ROI: 3.96%
Off Pcr 914 Perryville, MO Off Pcr 914, Perryville, MO 63775 \| Other	N/A beds \| N/A baths \| N/A	$144,960	Airbnb cash on cash: -2.98% Traditional cash on cash: 3.36% Airbnb Rental Income: $167 Traditional Rental Income: $831 Airbnb ROI: -2.98% Traditional ROI: 3.36%

Real Estate investment in Perryville, MO

There are 94 properties for sale in the city of Perryville . The median list price in Perryville is $207,876 and the average price per square foot is $113. In October 2026, the average monthly cash on cash return in Perryville is 4.00%. The average monthly rental income in Perryville is $1,160.

Perryville, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 94 investment properties available for sale in Perryville.

In 2026, the best neighborhood to buy investment property is Perryville.

The ROI for Long-Term is higher than the Short-Term in Perryville with average rental income of $1,160.

Your search for investment property begins and ends here

Investment Property for Sale in Perryville, MO

2979 Pcr 501

Perryville, MO

3 beds | 1 baths | 960 sq.ft.

$130,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.92%

Airbnb Rental Income: $null

Traditional Rental Income: $1022

Airbnb ROI: N/A

Traditional ROI: 5.92%

44 Hopi Ln

Perryville, MO

2 beds | 1 baths | 840 sq.ft.

$159,000

Airbnb cash on cash: 0.49%

Traditional cash on cash: 3.32%

Airbnb Rental Income: $719

Traditional Rental Income: $840

Airbnb ROI: 0.49%

Traditional ROI: 3.32%

1606 Old Saint Marys Rd

Perryville, MO

4 beds | 1 baths | 1,215 sq.ft.

$215,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.52%

Airbnb Rental Income: $null

Traditional Rental Income: $1501

Airbnb ROI: N/A

Traditional ROI: 5.52%

815 Ridge Dr

Perryville, MO

3 beds | 3 baths | 3,564 sq.ft.

$295,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.86%

Airbnb Rental Income: $null

Traditional Rental Income: $1872

Airbnb ROI: N/A

Traditional ROI: 4.86%

114 Edwards St

Perryville, MO

3 beds | 1 baths | 1,064 sq.ft.

$109,900

Airbnb cash on cash: N/A

Traditional cash on cash: 8.61%

Airbnb Rental Income: $null

Traditional Rental Income: $1203

Airbnb ROI: N/A

Traditional ROI: 8.61%

1240 Drury Ln

Perryville, MO

3 beds | 2 baths | 1,955 sq.ft.

$284,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.08%

Airbnb Rental Income: $null

Traditional Rental Income: $2150

Airbnb ROI: N/A

Traditional ROI: 6.08%

2759 Pcr 910

Perryville, MO

3 beds | 2 baths | 2,208 sq.ft.

$1,498,000

Airbnb cash on cash: N/A

Traditional cash on cash: 0.42%

Airbnb Rental Income: $null

Traditional Rental Income: $2175

Airbnb ROI: N/A

Traditional ROI: 0.42%

814 Star St

Perryville, MO

2 beds | 1 baths | 940 sq.ft.

$158,900

Airbnb cash on cash: 0.56%

Traditional cash on cash: 5.57%

Airbnb Rental Income: $719

Traditional Rental Income: $1171

Airbnb ROI: 0.56%