Real Estate Investment Properties for Sale in Poplar Bluff, MO

Looking for investment property in Poplar Bluff, MO with high ROI ?

Explore a variety of short-term homes & houses in Poplar Bluff, MO. Invest wisely with VRBO & Poplar Bluff, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Poplar Bluff, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2022 Snider Road Poplar Bluff, MO Stunning 3-Bedroom Home with Sunroom & Community Pool Access! Step into this fully remodel...	3 beds \| 2 baths \| 2,176 sq.ft.	$249,500	Airbnb cash on cash: 0.42% Traditional cash on cash: 6.63% Airbnb Rental Income: $861 Traditional Rental Income: $1992 Airbnb ROI: 0.42% Traditional ROI: 6.63%
501 N 16th Street Poplar Bluff, MO Check out this recently remodeled 4 bed, 3 1/2 bath home! This home is conveniently locate...	4 beds \| 4 baths \| 2,520 sq.ft.	$240,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.64% Airbnb Rental Income: $null Traditional Rental Income: $2837 Airbnb ROI: N/A Traditional ROI: 10.64%
5989 Melissa Lane Poplar Bluff, MO Welcome to 5989 Melissa Lane, a charming and well-kept home in Poplar Bluff, Missouri. Thi...	3 beds \| 2 baths \| 1,350 sq.ft.	$229,900	Airbnb cash on cash: 0.51% Traditional cash on cash: 6.03% Airbnb Rental Income: $861 Traditional Rental Income: $1728 Airbnb ROI: 0.51% Traditional ROI: 6.03%
2121 Pike Street Poplar Bluff, MO Completely remodeled 3 bedroom, 2 bath home that has a spacious 20' x 16' primary bedroom,...	3 beds \| 2 baths \| 1,331 sq.ft.	$154,000	Airbnb cash on cash: 1.4% Traditional cash on cash: 9.67% Airbnb Rental Income: $861 Traditional Rental Income: $1746 Airbnb ROI: 1.4% Traditional ROI: 9.67%
2006 Holloway Drive Poplar Bluff, MO Beautifully renovated/ completely remodeled, 4-bedroom, 3-bath brick home on a corner lot ...	4 beds \| 3 baths \| 2,410 sq.ft.	$299,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.11% Airbnb Rental Income: $null Traditional Rental Income: $2503 Airbnb ROI: N/A Traditional ROI: 7.11%
110 Hampton Ct Poplar Bluff, MO Situated on a desirable corner lot, this property features a two-car attached garage plus ...	3 beds \| 2 baths \| 1,255 sq.ft.	$129,900	Airbnb cash on cash: 1.96% Traditional cash on cash: 11.4% Airbnb Rental Income: $861 Traditional Rental Income: $1708 Airbnb ROI: 1.96% Traditional ROI: 11.4%
197 Rabbit Run Road Poplar Bluff, MO Charming home with 4-car garage! This classic 1,960 sq ft home offers 3 bedrooms, 2 bathro...	3 beds \| 2 baths \| 1,960 sq.ft.	$259,000	Airbnb cash on cash: 0.28% Traditional cash on cash: 6.82% Airbnb Rental Income: $861 Traditional Rental Income: $2128 Airbnb ROI: 0.28% Traditional ROI: 6.82%
1423 Woodland Poplar Bluff, MO This 2,340 square ft. home sitting in a quiet neighborhood right behind the VA Hospital is...	3 beds \| 2 baths \| 2,340 sq.ft.	$189,500	Airbnb cash on cash: 0.92% Traditional cash on cash: 11.43% Airbnb Rental Income: $861 Traditional Rental Income: $2421 Airbnb ROI: 0.92% Traditional ROI: 11.43%
1947 Glendale Road Poplar Bluff, MO Welcome to this move-in ready brick home nestled in the peaceful Town & Country neighborho...	3 beds \| 2 baths \| 1,216 sq.ft.	$129,900	Airbnb cash on cash: 1.97% Traditional cash on cash: 10.69% Airbnb Rental Income: $861 Traditional Rental Income: $1618 Airbnb ROI: 1.97% Traditional ROI: 10.69%
5100 Crabapple Lane Poplar Bluff, MO Welcome to this beautifully maintained 3-bedroom, 2-bathroom home located in a highly soug...	3 beds \| 2 baths \| 1,537 sq.ft.	$219,900	Airbnb cash on cash: 0.55% Traditional cash on cash: 6.85% Airbnb Rental Income: $861 Traditional Rental Income: $1842 Airbnb ROI: 0.55% Traditional ROI: 6.85%
1172 Hwy NN Poplar Bluff, MO BONUS OPPORTUNITY: An Additional adjacent acre with a second home is available for purchas...	4 beds \| 3 baths \| 2,770 sq.ft.	$378,999	Airbnb cash on cash: N/A Traditional cash on cash: 5.75% Airbnb Rental Income: $null Traditional Rental Income: $2636 Airbnb ROI: N/A Traditional ROI: 5.75%
1005 E Donna Drive Poplar Bluff, MO Welcome to this beautiful 4 bedroom, 2 bath home built in 2019, offering the perfect mix o...	4 beds \| 2 baths \| 1,871 sq.ft.	$270,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.55% Airbnb Rental Income: $null Traditional Rental Income: $2158 Airbnb ROI: N/A Traditional ROI: 6.55%
2125 Barron Road Poplar Bluff, MO Stunning Remodeled Home on Almost an Acre â North Town Location! 4 Bed \| 2 Bath \| 2,626 ...	4 beds \| 2 baths \| 2,626 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.84% Airbnb Rental Income: $null Traditional Rental Income: $2345 Airbnb ROI: N/A Traditional ROI: 7.84%
2105 Jackson Road Poplar Bluff, MO 2022 Remodel!! 4BR/4BA home in the desirable Haven Hills subdivision, centrally located in...	4 beds \| 4 baths \| 3,759 sq.ft.	$399,300	Airbnb cash on cash: N/A Traditional cash on cash: 8.4% Airbnb Rental Income: $null Traditional Rental Income: $3747 Airbnb ROI: N/A Traditional ROI: 8.4%
1415 Woodland RD. Poplar Bluff, MO Nice 3 bedroom, 1.5 bath with some hardwood flooring, utility and storage room off carport...	3 beds \| 2 baths \| 1,200 sq.ft.	$139,500	Airbnb cash on cash: 1.85% Traditional cash on cash: 9.46% Airbnb Rental Income: $861 Traditional Rental Income: $1546 Airbnb ROI: 1.85% Traditional ROI: 9.46%
1288 County Road 488 Poplar Bluff, MO Spacious 5-bedroom, 3-bathroom home situated on 5 acres +/- just outside of Poplar Bluff. ...	5 beds \| 3 baths \| 3,227 sq.ft.	$482,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.66% Airbnb Rental Income: $null Traditional Rental Income: $1907 Airbnb ROI: N/A Traditional ROI: 2.66%
112 Mayson Lane Poplar Bluff, MO New construction 3 bedroom, 2.5 bath home. This subdivision is designed for people looking...	3 beds \| 3 baths \| 1,545 sq.ft.	$209,000	Airbnb cash on cash: 0.59% Traditional cash on cash: 7.33% Airbnb Rental Income: $861 Traditional Rental Income: $1864 Airbnb ROI: 0.59% Traditional ROI: 7.33%
547 County Road 448 Poplar Bluff, MO This is a one of a kind property. This can be a multi-family home, a single family home or...	4 beds \| 4 baths \| 4,364 sq.ft.	$475,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.3% Airbnb Rental Income: $null Traditional Rental Income: $3501 Airbnb ROI: N/A Traditional ROI: 6.3%
318 E Henry Street Poplar Bluff, MO Move-in ready and beautifully remodeled. This 3-bedroom, 2-bath home has been thoughtfully...	3 beds \| 2 baths \| 1,606 sq.ft.	$164,900	Airbnb cash on cash: -0.01% Traditional cash on cash: 9.21% Airbnb Rental Income: $615 Traditional Rental Income: $1774 Airbnb ROI: -0.01% Traditional ROI: 9.21%
5711 Cedar Valley Drive Poplar Bluff, MO This may be the one you've been looking for! Many upgrades to this 3 bedroom, 2 bath home ...	3 beds \| 2 baths \| 1,715 sq.ft.	$219,900	Airbnb cash on cash: 0.62% Traditional cash on cash: 6.21% Airbnb Rental Income: $861 Traditional Rental Income: $1693 Airbnb ROI: 0.62% Traditional ROI: 6.21%
267 Misty Lake Road Poplar Bluff, MO Beautifully updated brick home on 3 acres m/l with Lake View and shop building. Looking fo...	4 beds \| 3 baths \| 2,600 sq.ft.	$389,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.19% Airbnb Rental Income: $null Traditional Rental Income: $2453 Airbnb ROI: N/A Traditional ROI: 5.19%
243 Hampton Court Poplar Bluff, MO Check out this charming 3 bedroom, 1 bath house! Brick exterior with recent updates. Rea...	3 beds \| 1 baths \| 1,296 sq.ft.	$139,900	Airbnb cash on cash: 1.83% Traditional cash on cash: 7.78% Airbnb Rental Income: $861 Traditional Rental Income: $1327 Airbnb ROI: 1.83% Traditional ROI: 7.78%
1043 Hwy AA Poplar Bluff, MO Looking for a great investment! Nice brick home with 4 income producing rentals on this pr...	3 beds \| 2 baths \| 1,388 sq.ft.	$239,900	Airbnb cash on cash: -0.04% Traditional cash on cash: 5.14% Airbnb Rental Income: $861 Traditional Rental Income: $1704 Airbnb ROI: -0.04% Traditional ROI: 5.14%
1006 Hickory Street Poplar Bluff, MO Welcome to this spacious 4 bedroom, 2 bath home located right in the heart of town! Offeri...	4 beds \| 2 baths \| 1,514 sq.ft.	$140,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.76% Airbnb Rental Income: $null Traditional Rental Income: $1859 Airbnb ROI: N/A Traditional ROI: 11.76%
1202 Victoria Rd Poplar Bluff, MO 1202 Victoria Rd, Poplar Bluff, MO 63901; Check out this classic, ranch style home with 1,...	3 beds \| 2 baths \| 1,458 sq.ft.	$199,900	Airbnb cash on cash: 0.76% Traditional cash on cash: 7.07% Airbnb Rental Income: $861 Traditional Rental Income: $1726 Airbnb ROI: 0.76% Traditional ROI: 7.07%
813 Kendall Drive Poplar Bluff, MO Charming 3-bedroom, 1-bathroom home in Poplar Bluff, MO, offering 1,120 sq ft of living sp...	3 beds \| 1 baths \| 1,120 sq.ft.	$117,000	Airbnb cash on cash: 2.44% Traditional cash on cash: 10.47% Airbnb Rental Income: $861 Traditional Rental Income: $1436 Airbnb ROI: 2.44% Traditional ROI: 10.47%
1102 Highway 142 Poplar Bluff, MO This 2-bedroom, 2-bathroom home has been fully remodeled from the top to the bottom and is...	2 beds \| 2 baths \| 1,410 sq.ft.	$169,900	Airbnb cash on cash: 2.82% Traditional cash on cash: 9.04% Airbnb Rental Income: $1129 Traditional Rental Income: $1759 Airbnb ROI: 2.82% Traditional ROI: 9.04%
2116 County Road 607 Poplar Bluff, MO Charming, 3 bedroom, 2 bath manufactured home with shop on nearly 1 acre M/L ! Discover th...	3 beds \| 2 baths \| 1,942 sq.ft.	$177,900	Airbnb cash on cash: 1.07% Traditional cash on cash: 10.47% Airbnb Rental Income: $861 Traditional Rental Income: $2120 Airbnb ROI: 1.07% Traditional ROI: 10.47%
225 S 6th Street Poplar Bluff, MO Built in 1917, the Corrigan House is a distinguished Neocolonial-style home listed on the ...	5 beds \| 4 baths \| 6,749 sq.ft.	$530,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.72% Airbnb Rental Income: $null Traditional Rental Income: $4055 Airbnb ROI: N/A Traditional ROI: 6.72%
146 Hampton Court Poplar Bluff, MO This stunning all-brick construction 4-bedroom, 2-bath home offers nearly 1,700 sq. ft. of...	4 beds \| 2 baths \| 1,680 sq.ft.	$169,500	Airbnb cash on cash: N/A Traditional cash on cash: 9.51% Airbnb Rental Income: $null Traditional Rental Income: $1860 Airbnb ROI: N/A Traditional ROI: 9.51%
542 County Road 323 Poplar Bluff, MO Discover the perfect blend of comfort and country living with this stunning 4-bedroom, 3.5...	4 beds \| 4 baths \| 2,312 sq.ft.	$269,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.74% Airbnb Rental Income: $null Traditional Rental Income: $2807 Airbnb ROI: N/A Traditional ROI: 8.74%
712 Nickey Street Poplar Bluff, MO Welcome to this cozy home, situated on a spacious double lot directly across from Eugene F...	2 beds \| 1 baths \| 952 sq.ft.	$89,900	Airbnb cash on cash: 6.24% Traditional cash on cash: 11.31% Airbnb Rental Income: $1129 Traditional Rental Income: $1198 Airbnb ROI: 6.24% Traditional ROI: 11.31%
136 Rhinestone Ln Poplar Bluff, MO Welcome to this stunning, completely remodeled 5-bedroom, 3-bath home with a 2-car garage,...	5 beds \| 3 baths \| 3,410 sq.ft.	$234,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.67% Airbnb Rental Income: $null Traditional Rental Income: $2794 Airbnb ROI: N/A Traditional ROI: 10.67%

Real Estate investment in Poplar-bluff, MO

There are 87 properties for sale in the city of Poplar Bluff . The median list price in Poplar Bluff is $201,200 and the average price per square foot is $92. In October 2025, the average monthly cash on cash return in Poplar Bluff is 9.00%. The average monthly rental income in Poplar Bluff is $1,860.

Poplar-bluff, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 87 investment properties available for sale in Poplar-bluff.

In 2025, the best neighborhood to buy investment property is Poplar Bluff.

The ROI for Long-Term is higher than the Short-Term in Poplar-bluff with average rental income of $1,860.

Your search for investment property begins and ends here

Investment Property for Sale in Poplar Bluff, MO

2022 Snider Road

Poplar Bluff, MO

3 beds | 2 baths | 2,176 sq.ft.

$249,500

Airbnb cash on cash: 0.42%

Traditional cash on cash: 6.63%

Airbnb Rental Income: $861

Traditional Rental Income: $1992

Airbnb ROI: 0.42%

Traditional ROI: 6.63%

501 N 16th Street

Poplar Bluff, MO

4 beds | 4 baths | 2,520 sq.ft.

$240,000

Airbnb cash on cash: N/A

Traditional cash on cash: 10.64%

Airbnb Rental Income: $null

Traditional Rental Income: $2837

Airbnb ROI: N/A

Traditional ROI: 10.64%

5989 Melissa Lane

Poplar Bluff, MO

3 beds | 2 baths | 1,350 sq.ft.

$229,900

Airbnb cash on cash: 0.51%

Traditional cash on cash: 6.03%

Airbnb Rental Income: $861

Traditional Rental Income: $1728

Airbnb ROI: 0.51%

Traditional ROI: 6.03%

2121 Pike Street

Poplar Bluff, MO

3 beds | 2 baths | 1,331 sq.ft.

$154,000

Airbnb cash on cash: 1.4%

Traditional cash on cash: 9.67%

Airbnb Rental Income: $861

Traditional Rental Income: $1746

Airbnb ROI: 1.4%

Traditional ROI: 9.67%

2006 Holloway Drive

Poplar Bluff, MO

4 beds | 3 baths | 2,410 sq.ft.

$299,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.11%

Airbnb Rental Income: $null

Traditional Rental Income: $2503

Airbnb ROI: N/A

Traditional ROI: 7.11%

110 Hampton Ct

Poplar Bluff, MO

3 beds | 2 baths | 1,255 sq.ft.

$129,900

Airbnb cash on cash: 1.96%

Traditional cash on cash: 11.4%

Airbnb Rental Income: $861

Traditional Rental Income: $1708

Airbnb ROI: 1.96%

Traditional ROI: 11.4%

197 Rabbit Run Road

Poplar Bluff, MO

3 beds | 2 baths | 1,960 sq.ft.

$259,000

Airbnb cash on cash: 0.28%

Traditional cash on cash: 6.82%

Airbnb Rental Income: $861

Traditional Rental Income: $2128

Airbnb ROI: 0.28%

Traditional ROI: 6.82%

1423 Woodland

Poplar Bluff, MO

3 beds | 2 baths | 2,340 sq.ft.

$189,500

Airbnb cash on cash: 0.92%

Traditional cash on cash: 11.43%

Airbnb Rental Income: $861

Traditional Rental Income: $2421

Airbnb ROI: 0.92%