Real Estate Investment Properties for Sale in Poplar Bluff, MO

Looking for investment property in Poplar Bluff, MO with high ROI ?

Explore a variety of short-term homes & houses in Poplar Bluff, MO. Invest wisely with VRBO & Poplar Bluff, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Poplar Bluff, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2305 Lee St Poplar Bluff, MO Welcome to this charming 3-bedroom, 2-bath home tucked away on a quiet dead-end street, of...	3 beds \| 2 baths \| 2,124 sq.ft.	$259,900	Airbnb cash on cash: -1.59% Traditional cash on cash: 6.8% Airbnb Rental Income: $316 Traditional Rental Income: $2132 Airbnb ROI: -1.59% Traditional ROI: 6.8%
501 N 16th Street Poplar Bluff, MO Check out this recently remodeled 5 bed, 3 1/2 bath home! This home is conveniently locate...	5 beds \| 4 baths \| 2,520 sq.ft.	$215,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.93% Airbnb Rental Income: $null Traditional Rental Income: $2837 Airbnb ROI: N/A Traditional ROI: 11.93%
2151 J Bird Ln Poplar Bluff, MO 4 bd, 3 bath vinyl sided home. Large open living room with vaulted ceiling, all stainless ...	4 beds \| 3 baths \| 2,650 sq.ft.	$315,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.58% Airbnb Rental Income: $null Traditional Rental Income: $2199 Airbnb ROI: N/A Traditional ROI: 5.58%
2184 J Bird Ln Poplar Bluff, MO Very nice 4 bedroom 3 bath home with spacious rooms, large master bdrm & bath, with ...	4 beds \| 3 baths \| 3,200 sq.ft.	$369,500	Airbnb cash on cash: N/A Traditional cash on cash: 4.28% Airbnb Rental Income: $null Traditional Rental Income: $2101 Airbnb ROI: N/A Traditional ROI: 4.28%
2613 N 14th Street Poplar Bluff, MO A must see; with many so updates and oversized, this 3 bedroom 2 full bath home has so muc...	3 beds \| 2 baths \| 2,544 sq.ft.	$249,000	Airbnb cash on cash: -1.49% Traditional cash on cash: 8.31% Airbnb Rental Income: $316 Traditional Rental Income: $2378 Airbnb ROI: -1.49% Traditional ROI: 8.31%
1905 Seifert Drive Poplar Bluff, MO Welcome to this charming and beautifully updated 3 bedroom, 2 bath home offering 1,596 +/-...	3 beds \| 2 baths \| 1,596 sq.ft.	$179,500	Airbnb cash on cash: -1.47% Traditional cash on cash: 8.78% Airbnb Rental Income: $316 Traditional Rental Income: $1826 Airbnb ROI: -1.47% Traditional ROI: 8.78%
1915 Old Orchard Rd Poplar Bluff, MO $139,500, 1915 Old Orchard Road, PB. Very sound and well maintained 3 bedroom, 2.5 bathroo...	3 beds \| 2 baths \| 2,134 sq.ft.	$254,900	Airbnb cash on cash: -1.47% Traditional cash on cash: 6.06% Airbnb Rental Income: $316 Traditional Rental Income: $1886 Airbnb ROI: -1.47% Traditional ROI: 6.06%
2826 Highway T Poplar Bluff, MO Acreage, Shop, Pond!! Enjoy ample room to relax, entertain, create, and live your dream w...	5 beds \| 4 baths \| 4,240 sq.ft.	$650,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.71% Airbnb Rental Income: $null Traditional Rental Income: $3125 Airbnb ROI: N/A Traditional ROI: 3.71%
2001 King Rd Poplar Bluff, MO Take a look at this beautiful all electric ranch style, 3 bedroom, 2 3/4 bath home with ga...	3 beds \| 3 baths \| 3,134 sq.ft.	$270,000	Airbnb cash on cash: -1.61% Traditional cash on cash: 5.93% Airbnb Rental Income: $316 Traditional Rental Income: $1992 Airbnb ROI: -1.61% Traditional ROI: 5.93%
1172 Hwy NN Poplar Bluff, MO Step inside to discover a recently updated interior featuring a spacious bonus room, ideal...	4 beds \| 3 baths \| 2,770 sq.ft.	$359,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.1% Airbnb Rental Income: $null Traditional Rental Income: $2636 Airbnb ROI: N/A Traditional ROI: 6.1%
2700 Holly Trail Poplar Bluff, MO This impressive brick quadplex is situated just north of Poplar Bluff, conveniently positi...	N/A beds \| N/A baths \| N/A	$315,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.91% Airbnb Rental Income: $null Traditional Rental Income: $1405 Airbnb ROI: N/A Traditional ROI: 2.91%
109 Lanee Lane Poplar Bluff, MO Like new 4 bedroom, 2 bath home on nice 0.4 +/- acre lot adjoining large wooded tract. Gre...	4 beds \| 2 baths \| 1,979 sq.ft.	$294,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.06% Airbnb Rental Income: $null Traditional Rental Income: $2240 Airbnb ROI: N/A Traditional ROI: 6.06%
2013 Tumbleweed Trail Poplar Bluff, MO Beautiful 3 bedroom, 2 bath home on a corner lot in Still Creek Crossing subdivision. This...	3 beds \| 2 baths \| 1,570 sq.ft.	$269,900	Airbnb cash on cash: -1.68% Traditional cash on cash: 5.19% Airbnb Rental Income: $316 Traditional Rental Income: $1823 Airbnb ROI: -1.68% Traditional ROI: 5.19%
2105 Jackson Road Poplar Bluff, MO 2022 Remodel!! 4BR/4BA home in the desirable Haven Hills subdivision, centrally located in...	4 beds \| 4 baths \| 3,759 sq.ft.	$389,400	Airbnb cash on cash: N/A Traditional cash on cash: 8.63% Airbnb Rental Income: $null Traditional Rental Income: $3747 Airbnb ROI: N/A Traditional ROI: 8.63%
1508 Bethel Street Poplar Bluff, MO This charming 3-bedroom, 1-bath home has been well loved by its previous owner and is read...	3 beds \| 1 baths \| 754 sq.ft.	$86,500	Airbnb cash on cash: -1.52% Traditional cash on cash: 6.23% Airbnb Rental Income: $316 Traditional Rental Income: $731 Airbnb ROI: -1.52% Traditional ROI: 6.23%
2855 Lakeside Drive Poplar Bluff, MO This beautiful 4-bedroom, 3-bath brick home offers exceptional curb appeal and a location ...	4 beds \| 3 baths \| 2,293 sq.ft.	$224,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.09% Airbnb Rental Income: $null Traditional Rental Income: $1706 Airbnb ROI: N/A Traditional ROI: 6.09%
2911 Oak Grove Road Poplar Bluff, MO Location, location, location! This property offers endless possibilities with C-2 commerci...	4 beds \| 2 baths \| 1,792 sq.ft.	$449,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.4% Airbnb Rental Income: $null Traditional Rental Income: $2053 Airbnb ROI: N/A Traditional ROI: 3.4%
1149 Mistletoe Ln Poplar Bluff, MO 3 bed 1.5 bath single story home with high visibility from Kanell/ PP Hwy. 30x60 detached...	N/A beds \| N/A baths \| 1,790 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.61% Airbnb Rental Income: $null Traditional Rental Income: $2024 Airbnb ROI: N/A Traditional ROI: 5.61%
233 Anna Drive Poplar Bluff, MO Build in 2014, this stunning split-level home blends thoughtful design with comfort and ch...	4 beds \| 3 baths \| 1,432 sq.ft.	$245,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.49% Airbnb Rental Income: $null Traditional Rental Income: $1281 Airbnb ROI: N/A Traditional ROI: 3.49%
4836 Highway M Poplar Bluff, MO Thoughtfully remodeled home boasting a blend of modern and rustic touches located just out...	4 beds \| 2 baths \| 1,300 sq.ft.	$189,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.31% Airbnb Rental Income: $null Traditional Rental Income: $1627 Airbnb ROI: N/A Traditional ROI: 7.31%
1329 Barron Road Poplar Bluff, MO NEW LISTING: Imagine yourself in your dream home in Poplar Bluff, where endless opportunit...	4 beds \| 2 baths \| 1,287 sq.ft.	$259,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.08% Airbnb Rental Income: $null Traditional Rental Income: $1939 Airbnb ROI: N/A Traditional ROI: 6.08%
647 County Road 470 Poplar Bluff, MO Lot size to be 4 acres m/l from a larger tract. Great location for this 3 bedroom (could b...	3 beds \| 2 baths \| 2,063 sq.ft.	$299,900	Airbnb cash on cash: -1.44% Traditional cash on cash: 6.34% Airbnb Rental Income: $316 Traditional Rental Income: $2271 Airbnb ROI: -1.44% Traditional ROI: 6.34%
2548 Stone Ridge Drive Poplar Bluff, MO Stately Brick Home in the north end of town, located on 1.11 Acres M/L. Timeless elegance ...	5 beds \| 5 baths \| 6,238 sq.ft.	$549,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.4% Airbnb Rental Income: $null Traditional Rental Income: $4297 Airbnb ROI: N/A Traditional ROI: 6.4%
547 County Road 448 Poplar Bluff, MO This is a one of a kind property. This can be a multi-family home, a single family home or...	4 beds \| 4 baths \| 4,364 sq.ft.	$440,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.88% Airbnb Rental Income: $null Traditional Rental Income: $3501 Airbnb ROI: N/A Traditional ROI: 6.88%
1301 Lurlyn Drive Poplar Bluff, MO Discover a refined country feeling right in the heart of town in this beautifully crafted ...	5 beds \| 4 baths \| 3,915 sq.ft.	$549,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.37% Airbnb Rental Income: $null Traditional Rental Income: $3192 Airbnb ROI: N/A Traditional ROI: 4.37%
291 Highway O Poplar Bluff, MO Versatile Land Opportunity in Southeast Missouri! Embrace the possibilities with this expa...	3 beds \| 2 baths \| 1,800 sq.ft.	$1,175,000	Airbnb cash on cash: -1.08% Traditional cash on cash: 0.75% Airbnb Rental Income: $316 Traditional Rental Income: $2073 Airbnb ROI: -1.08% Traditional ROI: 0.75%
2025 Wasson Drive Poplar Bluff, MO Spacious and well-maintained 5-bedroom, brick home, featuring 1.75 baths and a comfortable...	5 beds \| 2 baths \| 2,020 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.64% Airbnb Rental Income: $null Traditional Rental Income: $1937 Airbnb ROI: N/A Traditional ROI: 8.64%
4964 County Road 534 Poplar Bluff, MO If you enjoy the great outdoors, you have found your place. Just off T Hwy only minutes a...	3 beds \| 2 baths \| 1,424 sq.ft.	$320,000	Airbnb cash on cash: -1.37% Traditional cash on cash: 4.28% Airbnb Rental Income: $316 Traditional Rental Income: $1775 Airbnb ROI: -1.37% Traditional ROI: 4.28%
1043 Hwy AA Poplar Bluff, MO Looking for a great investment! Nice brick home with 4 income producing rentals on this pr...	3 beds \| 2 baths \| 1,388 sq.ft.	$239,900	Airbnb cash on cash: -2.04% Traditional cash on cash: 5.14% Airbnb Rental Income: $316 Traditional Rental Income: $1704 Airbnb ROI: -2.04% Traditional ROI: 5.14%
125 Perseverance Drive Poplar Bluff, MO Welcome home to this move-in-ready Craftsman-style ranch home, offering exceptional curb a...	3 beds \| 2 baths \| 1,404 sq.ft.	$240,000	Airbnb cash on cash: -1.57% Traditional cash on cash: 6.44% Airbnb Rental Income: $316 Traditional Rental Income: $1892 Airbnb ROI: -1.57% Traditional ROI: 6.44%
816 Kendall Avenue Poplar Bluff, MO Super Cute 2-bedroom, 1-bath home with a carport and a shed, which sits on a double lot.	2 beds \| 1 baths \| 1,065 sq.ft.	$122,000	Airbnb cash on cash: -0.08% Traditional cash on cash: 8.64% Airbnb Rental Income: $510 Traditional Rental Income: $1262 Airbnb ROI: -0.08% Traditional ROI: 8.64%
2116 County Road 607 Poplar Bluff, MO MOTIVATED SELLERS! Rare opportunity with a second lot and water/sewer hookups already in p...	3 beds \| 2 baths \| 1,942 sq.ft.	$172,900	Airbnb cash on cash: -1.54% Traditional cash on cash: 10.88% Airbnb Rental Income: $316 Traditional Rental Income: $2120 Airbnb ROI: -1.54% Traditional ROI: 10.88%
225 S 6th Street Poplar Bluff, MO Built in 1917, the Corrigan House is a distinguished Neocolonial-style home listed on the ...	5 beds \| 4 baths \| 6,749 sq.ft.	$325,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.51% Airbnb Rental Income: $null Traditional Rental Income: $4055 Airbnb ROI: N/A Traditional ROI: 11.51%
7209 Woodland Meadow Drive Poplar Bluff, MO Looking for a home thatâs already been updated? Check out this 4-bed, 3-bath beauty i...	4 beds \| 3 baths \| 2,072 sq.ft.	$279,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.54% Airbnb Rental Income: $null Traditional Rental Income: $2195 Airbnb ROI: N/A Traditional ROI: 6.54%
269 Berkshire Drive Poplar Bluff, MO This new construction 4 bedroom 2.5 bath home located in Legacy Estates will feature custo...	4 beds \| 3 baths \| 2,280 sq.ft.	$369,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.58% Airbnb Rental Income: $null Traditional Rental Income: $2746 Airbnb ROI: N/A Traditional ROI: 6.58%
3603 McLane Drive Poplar Bluff, MO Step into timeless elegance with this stunning 3 bedroom, 3 bath home nestled in a desirab...	3 beds \| 3 baths \| 2,735 sq.ft.	$429,500	Airbnb cash on cash: -1.45% Traditional cash on cash: 4.56% Airbnb Rental Income: $316 Traditional Rental Income: $2492 Airbnb ROI: -1.45% Traditional ROI: 4.56%
205 Batson Lake Lane Poplar Bluff, MO MOTIVATED SELLER! Enjoy peaceful country living in this 3 bedroom, 2 bath home on +/- 2.24...	3 beds \| 2 baths \| 1,200 sq.ft.	$219,900	Airbnb cash on cash: -1.13% Traditional cash on cash: 7.04% Airbnb Rental Income: $316 Traditional Rental Income: $1776 Airbnb ROI: -1.13% Traditional ROI: 7.04%
1507 Benton Street Poplar Bluff, MO Check out this recently remodeled 3 bedroom, 1 bath home in the heart of Poplar Bluff. Man...	3 beds \| 1 baths \| 1,415 sq.ft.	$129,900	Airbnb cash on cash: -1.5% Traditional cash on cash: 9.98% Airbnb Rental Income: $316 Traditional Rental Income: $1509 Airbnb ROI: -1.5% Traditional ROI: 9.98%

Real Estate investment in Poplar-bluff, MO

There are 147 properties for sale in the city of Poplar Bluff . The median list price in Poplar Bluff is $139,000 and the average price per square foot is $67. In May 2026, the average monthly cash on cash return in Poplar Bluff is 9.00%. The average monthly rental income in Poplar Bluff is $1,407.

Poplar-bluff, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 147 investment properties available for sale in Poplar-bluff.

In 2026, the best neighborhood to buy investment property is Poplar Bluff.

The ROI for Long-Term is higher than the Short-Term in Poplar-bluff with average rental income of $1,407.

Your search for investment property begins and ends here

Investment Property for Sale in Poplar Bluff, MO

2305 Lee St

Poplar Bluff, MO

3 beds | 2 baths | 2,124 sq.ft.

$259,900

Airbnb cash on cash: -1.59%

Traditional cash on cash: 6.8%

Airbnb Rental Income: $316

Traditional Rental Income: $2132

Airbnb ROI: -1.59%

Traditional ROI: 6.8%

501 N 16th Street

Poplar Bluff, MO

5 beds | 4 baths | 2,520 sq.ft.

$215,000

Airbnb cash on cash: N/A

Traditional cash on cash: 11.93%

Airbnb Rental Income: $null

Traditional Rental Income: $2837

Airbnb ROI: N/A

Traditional ROI: 11.93%

2151 J Bird Ln

Poplar Bluff, MO

4 beds | 3 baths | 2,650 sq.ft.

$315,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.58%

Airbnb Rental Income: $null

Traditional Rental Income: $2199

Airbnb ROI: N/A

Traditional ROI: 5.58%

2184 J Bird Ln

Poplar Bluff, MO

4 beds | 3 baths | 3,200 sq.ft.

$369,500

Airbnb cash on cash: N/A

Traditional cash on cash: 4.28%

Airbnb Rental Income: $null

Traditional Rental Income: $2101

Airbnb ROI: N/A

Traditional ROI: 4.28%

2613 N 14th Street

Poplar Bluff, MO

3 beds | 2 baths | 2,544 sq.ft.

$249,000

Airbnb cash on cash: -1.49%

Traditional cash on cash: 8.31%

Airbnb Rental Income: $316

Traditional Rental Income: $2378

Airbnb ROI: -1.49%

Traditional ROI: 8.31%

1905 Seifert Drive

Poplar Bluff, MO

3 beds | 2 baths | 1,596 sq.ft.

$179,500

Airbnb cash on cash: -1.47%

Traditional cash on cash: 8.78%

Airbnb Rental Income: $316

Traditional Rental Income: $1826

Airbnb ROI: -1.47%

Traditional ROI: 8.78%

1915 Old Orchard Rd

Poplar Bluff, MO

3 beds | 2 baths | 2,134 sq.ft.

$254,900

Airbnb cash on cash: -1.47%

Traditional cash on cash: 6.06%

Airbnb Rental Income: $316

Traditional Rental Income: $1886

Airbnb ROI: -1.47%

Traditional ROI: 6.06%

2826 Highway T

Poplar Bluff, MO

5 beds | 4 baths | 4,240 sq.ft.

$650,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.71%

Airbnb Rental Income: $null

Traditional Rental Income: $3125

Airbnb ROI: N/A