Real Estate Investment Properties for Sale in Poplar Bluff, MO

Looking for investment property in Poplar Bluff, MO with high ROI ?

Explore a variety of short-term homes & houses in Poplar Bluff, MO. Invest wisely with VRBO & Poplar Bluff, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Poplar Bluff, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
2305 Lee St Poplar Bluff, MO Welcome to this charming 3-bedroom, 2-bath home tucked away on a quiet dead-end street, of...	3 beds \| 2 baths \| 2,124 sq.ft.	$259,900	Airbnb cash on cash: -1.86% Traditional cash on cash: 6.8% Airbnb Rental Income: $236 Traditional Rental Income: $2132 Airbnb ROI: -1.86% Traditional ROI: 6.8%
501 N 16th Street Poplar Bluff, MO Check out this recently remodeled 5 bed, 3 1/2 bath home! This home is conveniently locate...	5 beds \| 4 baths \| 2,520 sq.ft.	$215,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.93% Airbnb Rental Income: $null Traditional Rental Income: $2837 Airbnb ROI: N/A Traditional ROI: 11.93%
5914 Melissa Lane Poplar Bluff, MO $229,900 5914 Melissa Lane, Poplar Bluff, Mo 63954 3 bed/2 bath in Shannon Cove Subdivis...	3 beds \| 2 baths \| 1,423 sq.ft.	$229,900	Airbnb cash on cash: -1.9% Traditional cash on cash: 6.32% Airbnb Rental Income: $236 Traditional Rental Income: $1796 Airbnb ROI: -1.9% Traditional ROI: 6.32%
354 Murfield Drive Poplar Bluff, MO Total Remodel 3 bedroom 2 bath 2 car garage w painted floor & new opener & key pad , Vau...	3 beds \| 2 baths \| 1,714 sq.ft.	$218,900	Airbnb cash on cash: -2.01% Traditional cash on cash: 7.16% Airbnb Rental Income: $236 Traditional Rental Income: $1909 Airbnb ROI: -2.01% Traditional ROI: 7.16%
1172 Hwy NN Poplar Bluff, MO Step inside to discover a recently updated interior featuring a spacious bonus room, ideal...	4 beds \| 3 baths \| 2,770 sq.ft.	$359,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.1% Airbnb Rental Income: $null Traditional Rental Income: $2636 Airbnb ROI: N/A Traditional ROI: 6.1%
2700 Holly Trail Poplar Bluff, MO This impressive brick quadplex is situated just north of Poplar Bluff, conveniently positi...	N/A beds \| N/A baths \| N/A	$315,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.91% Airbnb Rental Income: $null Traditional Rental Income: $1405 Airbnb ROI: N/A Traditional ROI: 2.91%
42 County Road 5651 Poplar Bluff, MO Nicely remodeled 4-bed, 1.75 bath home on appx. .78 acre m/l, open floor plan, stainless a...	4 beds \| 2 baths \| 1,196 sq.ft.	$134,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.21% Airbnb Rental Income: $null Traditional Rental Income: $1322 Airbnb ROI: N/A Traditional ROI: 8.21%
1189 Rocky Branch Lane Poplar Bluff, MO Looking for privacy, seclusion, and great hunting ground? This 3 bedroom, 2 bath home with...	3 beds \| 2 baths \| 2,496 sq.ft.	$315,000	Airbnb cash on cash: -1.63% Traditional cash on cash: 5.8% Airbnb Rental Income: $236 Traditional Rental Income: $2208 Airbnb ROI: -1.63% Traditional ROI: 5.8%
109 Lanee Lane Poplar Bluff, MO Like new 4 bedroom, 2 bath home on nice 0.4 +/- acre lot adjoining large wooded tract. Gre...	4 beds \| 2 baths \| 1,979 sq.ft.	$294,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.06% Airbnb Rental Income: $null Traditional Rental Income: $2240 Airbnb ROI: N/A Traditional ROI: 6.06%
2105 Jackson Road Poplar Bluff, MO 2022 Remodel!! 4BR/4BA home in the desirable Haven Hills subdivision, centrally located in...	4 beds \| 4 baths \| 3,759 sq.ft.	$389,400	Airbnb cash on cash: N/A Traditional cash on cash: 8.63% Airbnb Rental Income: $null Traditional Rental Income: $3747 Airbnb ROI: N/A Traditional ROI: 8.63%
1824 Seifert Drive Poplar Bluff, MO Charming, Updated Home in the Heart of Poplar BluffWelcome to this inviting 2-bedroom, 1-b...	2 beds \| 1 baths \| 800 sq.ft.	$125,000	Airbnb cash on cash: -0.17% Traditional cash on cash: 6.28% Airbnb Rental Income: $510 Traditional Rental Income: $1012 Airbnb ROI: -0.17% Traditional ROI: 6.28%
2855 Lakeside Drive Poplar Bluff, MO This beautiful 4-bedroom, 3-bath brick home offers exceptional curb appeal and a location ...	4 beds \| 3 baths \| 2,293 sq.ft.	$229,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.94% Airbnb Rental Income: $null Traditional Rental Income: $1706 Airbnb ROI: N/A Traditional ROI: 5.94%
2911 Oak Grove Road Poplar Bluff, MO Location, location, location! This property offers endless possibilities with C-2 commerci...	4 beds \| 2 baths \| 1,792 sq.ft.	$449,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.4% Airbnb Rental Income: $null Traditional Rental Income: $2053 Airbnb ROI: N/A Traditional ROI: 3.4%
696 Radcliff Lane Poplar Bluff, MO Beautifully updated home on 4.95 scenic fenced acres m/l with private lake access. If youâ...	3 beds \| 3 baths \| 2,096 sq.ft.	$449,900	Airbnb cash on cash: -1.48% Traditional cash on cash: 1.51% Airbnb Rental Income: $236 Traditional Rental Income: $1266 Airbnb ROI: -1.48% Traditional ROI: 1.51%
647 County Road 470 Poplar Bluff, MO Lot size to be 4 acres m/l from a larger tract. Great location for this 3 bedroom (could b...	3 beds \| 2 baths \| 2,063 sq.ft.	$299,900	Airbnb cash on cash: -1.68% Traditional cash on cash: 6.34% Airbnb Rental Income: $236 Traditional Rental Income: $2271 Airbnb ROI: -1.68% Traditional ROI: 6.34%
2548 Stone Ridge Drive Poplar Bluff, MO Stately Brick Home in the north end of town, located on 1.11 Acres M/L. Timeless elegance ...	5 beds \| 5 baths \| 6,238 sq.ft.	$549,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.4% Airbnb Rental Income: $null Traditional Rental Income: $4297 Airbnb ROI: N/A Traditional ROI: 6.4%
547 County Road 448 Poplar Bluff, MO This is a one of a kind property. This can be a multi-family home, a single family home or...	4 beds \| 4 baths \| 4,364 sq.ft.	$440,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.88% Airbnb Rental Income: $null Traditional Rental Income: $3501 Airbnb ROI: N/A Traditional ROI: 6.88%
1301 Lurlyn Drive Poplar Bluff, MO Discover a refined country feeling right in the heart of town in this beautifully crafted ...	5 beds \| 4 baths \| 3,915 sq.ft.	$549,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.37% Airbnb Rental Income: $null Traditional Rental Income: $3192 Airbnb ROI: N/A Traditional ROI: 4.37%
5711 Cedar Valley Drive Poplar Bluff, MO This may be the one you've been looking for! Many upgrades to this 3 bedroom, 2 bath home ...	3 beds \| 2 baths \| 1,715 sq.ft.	$209,900	Airbnb cash on cash: -1.92% Traditional cash on cash: 6.55% Airbnb Rental Income: $236 Traditional Rental Income: $1693 Airbnb ROI: -1.92% Traditional ROI: 6.55%
2025 Wasson Drive Poplar Bluff, MO Spacious and well-maintained 5-bedroom, brick home, featuring 1.75 baths and a comfortable...	5 beds \| 2 baths \| 2,020 sq.ft.	$189,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.64% Airbnb Rental Income: $null Traditional Rental Income: $1937 Airbnb ROI: N/A Traditional ROI: 8.64%
1043 Hwy AA Poplar Bluff, MO Looking for a great investment! Nice brick home with 4 income producing rentals on this pr...	3 beds \| 2 baths \| 1,388 sq.ft.	$239,900	Airbnb cash on cash: -2.34% Traditional cash on cash: 5.14% Airbnb Rental Income: $236 Traditional Rental Income: $1704 Airbnb ROI: -2.34% Traditional ROI: 5.14%
816 Kendall Avenue Poplar Bluff, MO Super Cute 2-bedroom, 1-bath home with a carport and a shed, which sits on a double lot.	2 beds \| 1 baths \| 1,065 sq.ft.	$127,000	Airbnb cash on cash: -0.12% Traditional cash on cash: 8.28% Airbnb Rental Income: $510 Traditional Rental Income: $1262 Airbnb ROI: -0.12% Traditional ROI: 8.28%
2116 County Road 607 Poplar Bluff, MO Rare opportunity with a second lot and water/sewer hookups already in place! This beautifu...	3 beds \| 2 baths \| 1,942 sq.ft.	$174,900	Airbnb cash on cash: -1.93% Traditional cash on cash: 10.75% Airbnb Rental Income: $236 Traditional Rental Income: $2120 Airbnb ROI: -1.93% Traditional ROI: 10.75%
225 S 6th Street Poplar Bluff, MO Built in 1917, the Corrigan House is a distinguished Neocolonial-style home listed on the ...	5 beds \| 4 baths \| 6,749 sq.ft.	$400,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.19% Airbnb Rental Income: $null Traditional Rental Income: $4055 Airbnb ROI: N/A Traditional ROI: 9.19%
2011 Woodland Road Poplar Bluff, MO $155,000 - 2011 Woodland Rd, Poplar Bluff, MO 63901. 3 bedroom, 1 bath, family room, 2 car...	3 beds \| 1 baths \| 1,497 sq.ft.	$155,000	Airbnb cash on cash: -2.13% Traditional cash on cash: 7.91% Airbnb Rental Income: $236 Traditional Rental Income: $1494 Airbnb ROI: -2.13% Traditional ROI: 7.91%
269 Berkshire Drive Poplar Bluff, MO This new construction 4 bedroom 2.5 bath home located in Legacy Estates will feature custo...	4 beds \| 3 baths \| 2,280 sq.ft.	$369,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.58% Airbnb Rental Income: $null Traditional Rental Income: $2746 Airbnb ROI: N/A Traditional ROI: 6.58%
2420 Channon Poplar Bluff, MO $129,900. 2420 Channon, Poplar Bluff, MO 63901. Remodeled, 3 bedroom house off of Barron R...	3 beds \| 1 baths \| 1,290 sq.ft.	$129,900	Airbnb cash on cash: -2.02% Traditional cash on cash: 9.56% Airbnb Rental Income: $236 Traditional Rental Income: $1454 Airbnb ROI: -2.02% Traditional ROI: 9.56%
3603 McLane Drive Poplar Bluff, MO Step into timeless elegance with this stunning 3 bedroom, 3 bath home nestled in a desirab...	3 beds \| 3 baths \| 2,735 sq.ft.	$429,500	Airbnb cash on cash: -1.62% Traditional cash on cash: 4.56% Airbnb Rental Income: $236 Traditional Rental Income: $2492 Airbnb ROI: -1.62% Traditional ROI: 4.56%
205 Batson Lake Lane Poplar Bluff, MO Enjoy peaceful country living in this 3 bedroom, 2 bath home on +/- 2.24 acres. Tucked awa...	3 beds \| 2 baths \| 1,200 sq.ft.	$219,900	Airbnb cash on cash: -1.45% Traditional cash on cash: 7.04% Airbnb Rental Income: $236 Traditional Rental Income: $1776 Airbnb ROI: -1.45% Traditional ROI: 7.04%
1507 Benton Street Poplar Bluff, MO Check out this recently remodeled 3 bedroom, 1 bath home in the heart of Poplar Bluff. Man...	3 beds \| 1 baths \| 1,415 sq.ft.	$135,000	Airbnb cash on cash: -2% Traditional cash on cash: 9.58% Airbnb Rental Income: $236 Traditional Rental Income: $1509 Airbnb ROI: -2% Traditional ROI: 9.58%
2801 Bedoll Avenue Poplar Bluff, MO Charming & Fully Remodeled Home in Poplar Bluff. Step inside this beautifully remodeled 3 ...	3 beds \| 3 baths \| 2,131 sq.ft.	$229,900	Airbnb cash on cash: -1.72% Traditional cash on cash: 8.7% Airbnb Rental Income: $236 Traditional Rental Income: $2276 Airbnb ROI: -1.72% Traditional ROI: 8.7%
1715 Big Bend Poplar Bluff, MO Step into this beautifully maintained 3 bedroom 2 full bath home offering 2,352 sq ft +/- ...	3 beds \| 2 baths \| 2,352 sq.ft.	$229,500	Airbnb cash on cash: -1.88% Traditional cash on cash: 8.6% Airbnb Rental Income: $236 Traditional Rental Income: $2284 Airbnb ROI: -1.88% Traditional ROI: 8.6%
1000 W Victor Street Poplar Bluff, MO This charming, fully remodeled 2-bedroom, 1-bath home on a corner lot has been updated wit...	2 beds \| 1 baths \| 672 sq.ft.	$78,900	Airbnb cash on cash: 0.5% Traditional cash on cash: 11.53% Airbnb Rental Income: $510 Traditional Rental Income: $1093 Airbnb ROI: 0.5% Traditional ROI: 11.53%
251 Hampton Court Poplar Bluff, MO This 3-bedroom,2 full bath, brick home offers the perfect blend of comfort and flexibility...	3 beds \| 2 baths \| 1,884 sq.ft.	$188,900	Airbnb cash on cash: -1.89% Traditional cash on cash: 9.61% Airbnb Rental Income: $236 Traditional Rental Income: $2071 Airbnb ROI: -1.89% Traditional ROI: 9.61%
3401 Normandy Road Poplar Bluff, MO Welcome to 3401 Normandy Road, nestled in the highly sought-after McClain Subdivision over...	4 beds \| 4 baths \| 4,322 sq.ft.	$625,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.61% Airbnb Rental Income: $null Traditional Rental Income: $3658 Airbnb ROI: N/A Traditional ROI: 4.61%
192 Bruce Poplar Bluff, MO This incomplete new build offers endless opportunities for a forever dream home or potenti...	4 beds \| 2 baths \| 2,100 sq.ft.	$239,900	Airbnb cash on cash: N/A Traditional cash on cash: 8.46% Airbnb Rental Income: $null Traditional Rental Income: $2270 Airbnb ROI: N/A Traditional ROI: 8.46%

Real Estate investment in Poplar-bluff, MO

There are 73 properties for sale in the city of Poplar Bluff . The median list price in Poplar Bluff is $189,400 and the average price per square foot is $99. In April 2026, the average monthly cash on cash return in Poplar Bluff is 9.00%. The average monthly rental income in Poplar Bluff is $1,685.

Poplar-bluff, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 73 investment properties available for sale in Poplar-bluff.

In 2026, the best neighborhood to buy investment property is Poplar Bluff.

The ROI for Long-Term is higher than the Short-Term in Poplar-bluff with average rental income of $1,685.

Your search for investment property begins and ends here

Investment Property for Sale in Poplar Bluff, MO

2305 Lee St

Poplar Bluff, MO

3 beds | 2 baths | 2,124 sq.ft.

$259,900

Airbnb cash on cash: -1.86%

Traditional cash on cash: 6.8%

Airbnb Rental Income: $236

Traditional Rental Income: $2132

Airbnb ROI: -1.86%

Traditional ROI: 6.8%

501 N 16th Street

Poplar Bluff, MO

5 beds | 4 baths | 2,520 sq.ft.

$215,000

Airbnb cash on cash: N/A

Traditional cash on cash: 11.93%

Airbnb Rental Income: $null

Traditional Rental Income: $2837

Airbnb ROI: N/A

Traditional ROI: 11.93%

5914 Melissa Lane

Poplar Bluff, MO

3 beds | 2 baths | 1,423 sq.ft.

$229,900

Airbnb cash on cash: -1.9%

Traditional cash on cash: 6.32%

Airbnb Rental Income: $236

Traditional Rental Income: $1796

Airbnb ROI: -1.9%

Traditional ROI: 6.32%

354 Murfield Drive

Poplar Bluff, MO

3 beds | 2 baths | 1,714 sq.ft.

$218,900

Airbnb cash on cash: -2.01%

Traditional cash on cash: 7.16%

Airbnb Rental Income: $236

Traditional Rental Income: $1909

Airbnb ROI: -2.01%

Traditional ROI: 7.16%

1172 Hwy NN

Poplar Bluff, MO

4 beds | 3 baths | 2,770 sq.ft.

$359,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.1%

Airbnb Rental Income: $null

Traditional Rental Income: $2636

Airbnb ROI: N/A

Traditional ROI: 6.1%

2700 Holly Trail

Poplar Bluff, MO

N/A beds | N/A baths | N/A

$315,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.91%

Airbnb Rental Income: $null

Traditional Rental Income: $1405

Airbnb ROI: N/A

Traditional ROI: 2.91%

42 County Road 5651

Poplar Bluff, MO

4 beds | 2 baths | 1,196 sq.ft.

$134,900

Airbnb cash on cash: N/A

Traditional cash on cash: 8.21%

Airbnb Rental Income: $null

Traditional Rental Income: $1322

Airbnb ROI: N/A

Traditional ROI: 8.21%

1189 Rocky Branch Lane

Poplar Bluff, MO

3 beds | 2 baths | 2,496 sq.ft.

$315,000

Airbnb cash on cash: -1.63%

Traditional cash on cash: 5.8%

Airbnb Rental Income: $236

Traditional Rental Income: $2208

Airbnb ROI: -1.63%