Real Estate Investment Properties for Sale in Seneca, MO

Looking for investment property in Seneca, MO with high ROI ?

Explore a variety of short-term homes & houses in Seneca, MO. Invest wisely with VRBO & Seneca, MO Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, MO

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
121 Fawn Trail Seneca, MO Tucked into one of Seneca's established neighborhoods, this beautiful 3-bedroom, 2-bath ho...	3 beds \| 2 baths \| 2,380 sq.ft.	$253,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.12% Airbnb Rental Income: $null Traditional Rental Income: $2219 Airbnb ROI: N/A Traditional ROI: 7.12%
2953 Rowan Drive Seneca, MO Multi-family property on 4.5 acres with income potential. Main home boasts 5 bedrooms/2 ba...	5 beds \| 2 baths \| 2,700 sq.ft.	$499,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.43% Airbnb Rental Income: $null Traditional Rental Income: $2327 Airbnb ROI: N/A Traditional ROI: 3.43%
1014 Cherokee Avenue Seneca, MO Experience refined elegance in this stunningly restored historic home, where timeless arch...	4 beds \| 3 baths \| 2,396 sq.ft.	$299,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.45% Airbnb Rental Income: $null Traditional Rental Income: $2573 Airbnb ROI: N/A Traditional ROI: 7.45%
12609 State Hwy 43 Seneca, MO Great investment property! Two mobile homes with storage that includes separate space for ...	3 beds \| 2 baths \| 1,216 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.59% Airbnb Rental Income: $null Traditional Rental Income: $1567 Airbnb ROI: N/A Traditional ROI: 5.59%
1020 Seneca Avenue Seneca, MO Charming 2-bedroom, 1-bath home in Seneca featuring thoughtful updates! This well-maintain...	2 beds \| 1 baths \| 1,000 sq.ft.	$119,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.6% Airbnb Rental Income: $null Traditional Rental Income: $1124 Airbnb ROI: N/A Traditional ROI: 7.6%
1418 Cherokee Avenue Seneca, MO Located right in front of the Seneca Fire Department. Conveniently located next restaurant...	4 beds \| 2 baths \| 1,737 sq.ft.	$169,900	Airbnb cash on cash: N/A Traditional cash on cash: 10.35% Airbnb Rental Income: $null Traditional Rental Income: $1991 Airbnb ROI: N/A Traditional ROI: 10.35%
608 Chippewa Street Seneca, MO Discover your perfect slice of small-town charm at 608 Chippewa St., Seneca, MO 64865! Nes...	2 beds \| 2 baths \| 1,085 sq.ft.	$174,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.52% Airbnb Rental Income: $null Traditional Rental Income: $1416 Airbnb ROI: N/A Traditional ROI: 6.52%
13860 Bethel Road Seneca, MO First time on the market! This one-owner Seneca home offers 3 beds, 2 baths, 2,128 sqft, a...	3 beds \| 2 baths \| 2,128 sq.ft.	$279,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.46% Airbnb Rental Income: $null Traditional Rental Income: $2151 Airbnb ROI: N/A Traditional ROI: 6.46%
606 Cemetery Road Seneca, MO Tucked inside Seneca city limits yet offering the peace and privacy of the countryside, th...	3 beds \| 2 baths \| 1,505 sq.ft.	$199,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.69% Airbnb Rental Income: $null Traditional Rental Income: $1845 Airbnb ROI: N/A Traditional ROI: 7.69%
1904 Cherry Street Seneca, MO Welcome home to this move-in ready 4-bedroom, 2.5-bath property perfectly situated on Cher...	4 beds \| 3 baths \| 2,773 sq.ft.	$269,900	Airbnb cash on cash: N/A Traditional cash on cash: 6.68% Airbnb Rental Income: $null Traditional Rental Income: $2291 Airbnb ROI: N/A Traditional ROI: 6.68%
106 Greenfield Circle Seneca, MO Welcome to 106 Greenfield Circle in Seneca, a 3-bedroom, 1-bathroom home offering 1,258 sq...	3 beds \| 1 baths \| 1,258 sq.ft.	$115,000	Airbnb cash on cash: N/A Traditional cash on cash: 9.86% Airbnb Rental Income: $null Traditional Rental Income: $1355 Airbnb ROI: N/A Traditional ROI: 9.86%
1306 Curtin Avenue Seneca, MO Charming home on a corner lot in Seneca School District. It has been remodeled with beauti...	2 beds \| 1 baths \| 1,204 sq.ft.	$175,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.11% Airbnb Rental Income: $null Traditional Rental Income: $979 Airbnb ROI: N/A Traditional ROI: 4.11%
8233 Alamo Lane Seneca, MO 3BD 2BA Log sided Home in the woods on nearly 5 acres w/ Huge shop/garage. Acreage is part...	3 beds \| 2 baths \| 1,584 sq.ft.	$399,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.11% Airbnb Rental Income: $null Traditional Rental Income: $1786 Airbnb ROI: N/A Traditional ROI: 3.11%
9698 Highway 43 Seneca, MO Not a cookie-cutter home! This spacious 3,187 sq ft property offers incredible flexibility...	3 beds \| 2 baths \| 3,187 sq.ft.	$349,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.23% Airbnb Rental Income: $null Traditional Rental Income: $1610 Airbnb ROI: N/A Traditional ROI: 3.23%
2010 Cherry Street Seneca, MO Welcome to the kind of home that just feels right from the moment you pull in. Tucked into...	4 beds \| 3 baths \| 2,783 sq.ft.	$349,500	Airbnb cash on cash: N/A Traditional cash on cash: 7.5% Airbnb Rental Income: $null Traditional Rental Income: $3043 Airbnb ROI: N/A Traditional ROI: 7.5%
2004 Elm Street Seneca, MO Step inside and instantly feel at home in a cozy living room, where the fireplace creates ...	4 beds \| 3 baths \| 1,536 sq.ft.	$229,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.65% Airbnb Rental Income: $null Traditional Rental Income: $2061 Airbnb ROI: N/A Traditional ROI: 7.65%
10302 W Highway 86 Seneca, MO Tucked into a beautiful hillside setting, this property sits on a spacious 1.5-acre lot of...	3 beds \| 2 baths \| 2,072 sq.ft.	$175,000	Airbnb cash on cash: N/A Traditional cash on cash: 5% Airbnb Rental Income: $null Traditional Rental Income: $1200 Airbnb ROI: N/A Traditional ROI: 5%
115 Fawn Trail Seneca, MO Beautiful brick-front home offering privacy with no neighbors directly behind. Built in 20...	3 beds \| 2 baths \| 1,517 sq.ft.	$229,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.37% Airbnb Rental Income: $null Traditional Rental Income: $1687 Airbnb ROI: N/A Traditional ROI: 5.37%
514 Ottawa Street Seneca, MO Property is freshly painted, remodeled and move in ready. New mini-systems heat and cool h...	2 beds \| 1 baths \| 1,053 sq.ft.	$89,900	Airbnb cash on cash: N/A Traditional cash on cash: 11.7% Airbnb Rental Income: $null Traditional Rental Income: $1236 Airbnb ROI: N/A Traditional ROI: 11.7%
12061 Crow Road Seneca, MO Peaceful country living on 1.86 acres in Seneca! This 3 bedroom, 2 bath manufactured home ...	3 beds \| 2 baths \| 1,152 sq.ft.	$135,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.63% Airbnb Rental Income: $null Traditional Rental Income: $1388 Airbnb ROI: N/A Traditional ROI: 8.63%

Real Estate investment in Seneca, MO

There are 20 properties for sale in the city of Seneca . The median list price in Seneca is $349,900 and the average price per square foot is $190. In April 2026, the average monthly cash on cash return in Seneca is 7.00%. The average monthly rental income in Seneca is $1,687.

Seneca, MO Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 20 investment properties available for sale in Seneca.

The ROI for Short-Term is higher than the Long-Term in Seneca with average rental income of $N/A.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, MO

121 Fawn Trail

Seneca, MO

3 beds | 2 baths | 2,380 sq.ft.

$253,000

Airbnb cash on cash: N/A

Traditional cash on cash: 7.12%

Airbnb Rental Income: $null

Traditional Rental Income: $2219

Airbnb ROI: N/A

Traditional ROI: 7.12%

2953 Rowan Drive

Seneca, MO

5 beds | 2 baths | 2,700 sq.ft.

$499,000

Airbnb cash on cash: N/A

Traditional cash on cash: 3.43%

Airbnb Rental Income: $null

Traditional Rental Income: $2327

Airbnb ROI: N/A

Traditional ROI: 3.43%

1014 Cherokee Avenue

Seneca, MO

4 beds | 3 baths | 2,396 sq.ft.

$299,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.45%

Airbnb Rental Income: $null

Traditional Rental Income: $2573

Airbnb ROI: N/A

Traditional ROI: 7.45%

12609 State Hwy 43

Seneca, MO

3 beds | 2 baths | 1,216 sq.ft.

$225,000

Airbnb cash on cash: N/A

Traditional cash on cash: 5.59%

Airbnb Rental Income: $null

Traditional Rental Income: $1567

Airbnb ROI: N/A

Traditional ROI: 5.59%

1020 Seneca Avenue

Seneca, MO

2 beds | 1 baths | 1,000 sq.ft.

$119,900

Airbnb cash on cash: N/A

Traditional cash on cash: 7.6%

Airbnb Rental Income: $null

Traditional Rental Income: $1124

Airbnb ROI: N/A

Traditional ROI: 7.6%

1418 Cherokee Avenue

Seneca, MO

4 beds | 2 baths | 1,737 sq.ft.

$169,900

Airbnb cash on cash: N/A

Traditional cash on cash: 10.35%

Airbnb Rental Income: $null

Traditional Rental Income: $1991

Airbnb ROI: N/A

Traditional ROI: 10.35%

608 Chippewa Street

Seneca, MO

2 beds | 2 baths | 1,085 sq.ft.

$174,900

Airbnb cash on cash: N/A

Traditional cash on cash: 6.52%

Airbnb Rental Income: $null

Traditional Rental Income: $1416

Airbnb ROI: N/A

Traditional ROI: 6.52%

13860 Bethel Road

Seneca, MO

3 beds | 2 baths | 2,128 sq.ft.

$279,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.46%

Airbnb Rental Income: $null

Traditional Rental Income: $2151

Airbnb ROI: N/A