Real Estate Investment Properties for Sale in Florence, SC

Looking for investment property in Florence, SC with high ROI ?

Explore a variety of short-term homes & houses in Florence, SC. Invest wisely with VRBO & Florence, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Florence, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
1905 Marsh Avenue Florence, SC From holiday gatherings in the formal dining room to quiet evenings by the gas log firepla...	3 beds \| 2 baths \| 1,670 sq.ft.	$239,900	Airbnb cash on cash: 1.8% Traditional cash on cash: 6.48% Airbnb Rental Income: $1188 Traditional Rental Income: $1861 Airbnb ROI: 1.8% Traditional ROI: 6.48%
337 Wilson Rd Florence, SC Welcome home to this charming 3-bedroom, 2-bath residence in Wilson Estates! Step inside t...	3 beds \| 2 baths \| 1,305 sq.ft.	$125,000	Airbnb cash on cash: 4.31% Traditional cash on cash: 11.6% Airbnb Rental Income: $1188 Traditional Rental Income: $1678 Airbnb ROI: 4.31% Traditional ROI: 11.6%
1914 Deerwood Place Florence, SC Welcome to 1914 Deerwood Place, a beautifully updated home tucked away on a quiet cul-de-s...	4 beds \| 3 baths \| 2,696 sq.ft.	$429,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.64% Airbnb Rental Income: $null Traditional Rental Income: $2819 Airbnb ROI: N/A Traditional ROI: 5.64%
2531 Kingston Dr. Florence, SC Welcome to 2531 Kingston Drive in the Parkwood neighborhood! This split-level home offers ...	3 beds \| 3 baths \| 1,884 sq.ft.	$279,900	Airbnb cash on cash: 1.5% Traditional cash on cash: 5.76% Airbnb Rental Income: $1188 Traditional Rental Income: $1925 Airbnb ROI: 1.5% Traditional ROI: 5.76%
2556 Kingston Drive Florence, SC Welcome to 2556 Kingston Drive in Florence's established Parkwood neighborhood. Situated o...	3 beds \| 3 baths \| 2,131 sq.ft.	$308,000	Airbnb cash on cash: 1.23% Traditional cash on cash: 6.22% Airbnb Rental Income: $1188 Traditional Rental Income: $2248 Airbnb ROI: 1.23% Traditional ROI: 6.22%
1671 Lake Wateree Drive Florence, SC Immaculate brick home located in the desirable West Lakes subdivision in Florence, SC, rea...	4 beds \| 3 baths \| 3,086 sq.ft.	$399,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.29% Airbnb Rental Income: $null Traditional Rental Income: $2663 Airbnb ROI: N/A Traditional ROI: 5.29%
3402 Shadow Creek Drive Florence, SC Welcome Home to this stunningly beautiful, custom home in Claussen Pointe! This home is si...	4 beds \| 3 baths \| 2,313 sq.ft.	$435,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.09% Airbnb Rental Income: $null Traditional Rental Income: $2399 Airbnb ROI: N/A Traditional ROI: 4.09%
3241 Lakeshore Drive Florence, SC Discover your perfect 4000 sq-ft, lakefront sanctuary in this stunning four-bedroom, four-...	4 beds \| 5 baths \| 4,000 sq.ft.	$829,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.17% Airbnb Rental Income: $null Traditional Rental Income: $5299 Airbnb ROI: N/A Traditional ROI: 5.17%
1007 W Palmetto St Florence, SC Step back in time with this 1933 Tudor-style landmark. This architectural treasure feature...	4 beds \| 4 baths \| 4,336 sq.ft.	$315,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.96% Airbnb Rental Income: $null Traditional Rental Income: $3806 Airbnb ROI: N/A Traditional ROI: 10.96%
1257 Calvin Circle Florence, SC Spacious single floor home in the established Sandhurst subdivision of Florence, South Car...	4 beds \| 3 baths \| 2,106 sq.ft.	$289,900	Airbnb cash on cash: N/A Traditional cash on cash: 7.13% Airbnb Rental Income: $null Traditional Rental Income: $2467 Airbnb ROI: N/A Traditional ROI: 7.13%
1716 Furman Drive Florence, SC Welcome home to 1716 Furman Drive in College Park! Perfectly located in the heart of Flore...	3 beds \| 2 baths \| 1,658 sq.ft.	$249,900	Airbnb cash on cash: 1.43% Traditional cash on cash: 6.03% Airbnb Rental Income: $1188 Traditional Rental Income: $1886 Airbnb ROI: 1.43% Traditional ROI: 6.03%
2130 Woodmore Circle Florence, SC Welcome to this 3-bedroom, 2-bath home featuring a 2-car attached garage and comfortable l...	3 beds \| 2 baths \| 1,757 sq.ft.	$199,900	Airbnb cash on cash: 0.94% Traditional cash on cash: 8.03% Airbnb Rental Income: $1188 Traditional Rental Income: $2145 Airbnb ROI: 0.94% Traditional ROI: 8.03%
1460 Chandler Circle Florence, SC	3 beds \| 3 baths \| 1,904 sq.ft.	$299,000	Airbnb cash on cash: 0.48% Traditional cash on cash: 5.5% Airbnb Rental Income: $1188 Traditional Rental Income: $2213 Airbnb ROI: 0.48% Traditional ROI: 5.5%
1031 Royal Street Florence, SC Looking for a unique opportunity? This is it! Great investment property that is ideally lo...	3 beds \| 1 baths \| 925 sq.ft.	$110,000	Airbnb cash on cash: 5.08% Traditional cash on cash: 8.99% Airbnb Rental Income: $1188 Traditional Rental Income: $1218 Airbnb ROI: 5.08% Traditional ROI: 8.99%
900 Sanborn Street Florence, SC Looking for a Unique Opportunity? Well, this is it! Great investment property that is idea...	3 beds \| 1 baths \| 1,065 sq.ft.	$118,000	Airbnb cash on cash: 4.65% Traditional cash on cash: 9.27% Airbnb Rental Income: $1188 Traditional Rental Income: $1328 Airbnb ROI: 4.65% Traditional ROI: 9.27%
308 E Summit Circle Florence, SC Take a look at this Unique Opportunity? This Great Investment Property is ideally located ...	3 beds \| 2 baths \| 1,025 sq.ft.	$139,000	Airbnb cash on cash: 3.74% Traditional cash on cash: 10.35% Airbnb Rental Income: $1188 Traditional Rental Income: $1683 Airbnb ROI: 3.74% Traditional ROI: 10.35%
419 Whitman Avenue Florence, SC Discover the charm of this beautifully renovated brick home located at 419 Whitman Ave, 29...	3 beds \| 2 baths \| 2,210 sq.ft.	$429,000	Airbnb cash on cash: 0.54% Traditional cash on cash: 3.18% Airbnb Rental Income: $1188 Traditional Rental Income: $1860 Airbnb ROI: 0.54% Traditional ROI: 3.18%
1431 Bourbon Drive Florence, SC Why wait for new construction when you can own this beautifully maintained, move-in ready ...	3 beds \| 2 baths \| 1,665 sq.ft.	$294,900	Airbnb cash on cash: 0.98% Traditional cash on cash: 4.76% Airbnb Rental Income: $1188 Traditional Rental Income: $1850 Airbnb ROI: 0.98% Traditional ROI: 4.76%
2109 Eaton Cir Florence, SC Renovated 2 years ago, 3 bedrooms, 1 /12 baths, all brick home, all new updated electric p...	3 beds \| 2 baths \| 1,154 sq.ft.	$209,900	Airbnb cash on cash: 1.99% Traditional cash on cash: 5.39% Airbnb Rental Income: $1188 Traditional Rental Income: $1479 Airbnb ROI: 1.99% Traditional ROI: 5.39%
3128 Harvard Way Florence, SC Unique neighborhood located in a convenient location. Enter the foyer with gorgeous hardwo...	4 beds \| 4 baths \| 2,556 sq.ft.	$420,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.87% Airbnb Rental Income: $null Traditional Rental Income: $2232 Airbnb ROI: N/A Traditional ROI: 3.87%
3326 Lakeshore Drive Florence, SC Welcome to the charm and comfort of Forest Lake living in this beautiful 4 to 5 bedroom, 3...	5 beds \| 4 baths \| 3,798 sq.ft.	$569,900	Airbnb cash on cash: N/A Traditional cash on cash: 3.09% Airbnb Rental Income: $null Traditional Rental Income: $2571 Airbnb ROI: N/A Traditional ROI: 3.09%
130 Mustang Rd Florence, SC 2 Brick Ranch Homes---1) Home 3/1 Super Nice inside & 1 - Brick Ranch Home 3/2 coming avai...	3 beds \| 1 baths \| 1,316 sq.ft.	$449,900	Airbnb cash on cash: 0.31% Traditional cash on cash: 1.63% Airbnb Rental Income: $1188 Traditional Rental Income: $1356 Airbnb ROI: 0.31% Traditional ROI: 1.63%
912 Camp Wiggins Rd. Florence, SC Enjoy the freedom of country living with NO HOA in this spaciously renovated brick home si...	3 beds \| 2 baths \| 2,028 sq.ft.	$285,000	Airbnb cash on cash: 1.07% Traditional cash on cash: 5.46% Airbnb Rental Income: $1188 Traditional Rental Income: $1979 Airbnb ROI: 1.07% Traditional ROI: 5.46%
2600 Kingston Dr. Florence, SC Welcome to 2600 Kingston Drive in the Parkwood neighborhood! This charming single-story ho...	3 beds \| 2 baths \| 1,428 sq.ft.	$225,000	Airbnb cash on cash: 2.26% Traditional cash on cash: 5.35% Airbnb Rental Income: $1188 Traditional Rental Income: $1461 Airbnb ROI: 2.26% Traditional ROI: 5.35%
1017 Alton Circle Florence, SC Located in one of Florence's established neighborhoods known for its walkability and bike-...	4 beds \| 3 baths \| 2,312 sq.ft.	$335,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.49% Airbnb Rental Income: $null Traditional Rental Income: $2314 Airbnb ROI: N/A Traditional ROI: 5.49%
313 S Gaillard St Florence, SC Three bedroom oand one bathroom home in Florence, SC is seconds from McLeod Hospital. With...	3 beds \| 1 baths \| 1,074 sq.ft.	$165,000	Airbnb cash on cash: 3.21% Traditional cash on cash: 6.99% Airbnb Rental Income: $1188 Traditional Rental Income: $1396 Airbnb ROI: 3.21% Traditional ROI: 6.99%
2220 Oakwood Lane APT A8 Florence, SC Welcome to your new home. Nestled within the quiet Foxboro Subdivision this beautiful 2 be...	2 beds \| 2 baths \| 1,088 sq.ft.	$118,000	Airbnb cash on cash: 3.2% Traditional cash on cash: 10.56% Airbnb Rental Income: $991 Traditional Rental Income: $1475 Airbnb ROI: 3.2% Traditional ROI: 10.56%
1454 Dorchester Road Florence, SC Stunning designer brick home situated on a premium, oversized corner lot! Every detail exu...	3 beds \| 3 baths \| 2,529 sq.ft.	$439,000	Airbnb cash on cash: 0.15% Traditional cash on cash: 3.8% Airbnb Rental Income: $1188 Traditional Rental Income: $2300 Airbnb ROI: 0.15% Traditional ROI: 3.8%
713 Bellemeade Circle Florence, SC Welcome to Wessex. This 4-bedroom, 3-bath home offers an open floor plan with functional s...	4 beds \| 3 baths \| 2,803 sq.ft.	$415,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.12% Airbnb Rental Income: $null Traditional Rental Income: $2619 Airbnb ROI: N/A Traditional ROI: 5.12%

Real Estate investment in Florence, SC

There are 258 properties for sale in the city of Florence . The median list price in Florence is $290,441 and the average price per square foot is $139. In July 2026, the average monthly cash on cash return in Florence is 6.00%. The average monthly rental income in Florence is $2,113.

Florence, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 258 investment properties available for sale in Florence.

In 2026, the best neighborhood to buy investment property is Florence.

The ROI for Long-Term is higher than the Short-Term in Florence with average rental income of $2,113.

Your search for investment property begins and ends here

Investment Property for Sale in Florence, SC

1905 Marsh Avenue

Florence, SC

3 beds | 2 baths | 1,670 sq.ft.

$239,900

Airbnb cash on cash: 1.8%

Traditional cash on cash: 6.48%

Airbnb Rental Income: $1188

Traditional Rental Income: $1861

Airbnb ROI: 1.8%

Traditional ROI: 6.48%

337 Wilson Rd

Florence, SC

3 beds | 2 baths | 1,305 sq.ft.

$125,000

Airbnb cash on cash: 4.31%

Traditional cash on cash: 11.6%

Airbnb Rental Income: $1188

Traditional Rental Income: $1678

Airbnb ROI: 4.31%

Traditional ROI: 11.6%

1914 Deerwood Place

Florence, SC

4 beds | 3 baths | 2,696 sq.ft.

$429,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.64%

Airbnb Rental Income: $null

Traditional Rental Income: $2819

Airbnb ROI: N/A

Traditional ROI: 5.64%

2531 Kingston Dr.

Florence, SC

3 beds | 3 baths | 1,884 sq.ft.

$279,900

Airbnb cash on cash: 1.5%

Traditional cash on cash: 5.76%

Airbnb Rental Income: $1188

Traditional Rental Income: $1925

Airbnb ROI: 1.5%

Traditional ROI: 5.76%

2556 Kingston Drive

Florence, SC

3 beds | 3 baths | 2,131 sq.ft.

$308,000

Airbnb cash on cash: 1.23%

Traditional cash on cash: 6.22%

Airbnb Rental Income: $1188

Traditional Rental Income: $2248

Airbnb ROI: 1.23%

Traditional ROI: 6.22%

1671 Lake Wateree Drive

Florence, SC

4 beds | 3 baths | 3,086 sq.ft.

$399,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.29%

Airbnb Rental Income: $null

Traditional Rental Income: $2663

Airbnb ROI: N/A

Traditional ROI: 5.29%

3402 Shadow Creek Drive

Florence, SC

4 beds | 3 baths | 2,313 sq.ft.

$435,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.09%

Airbnb Rental Income: $null

Traditional Rental Income: $2399

Airbnb ROI: N/A

Traditional ROI: 4.09%

3241 Lakeshore Drive

Florence, SC

4 beds | 5 baths | 4,000 sq.ft.

$829,900

Airbnb cash on cash: N/A

Traditional cash on cash: 5.17%

Airbnb Rental Income: $null

Traditional Rental Income: $5299

Airbnb ROI: N/A