Real Estate Investment Properties for Sale in Florence, SC

Looking for investment property in Florence, SC with high ROI ?

Explore a variety of short-term homes & houses in Florence, SC. Invest wisely with VRBO & Florence, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Florence, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
3207 Lakeshore Drive Florence, SC	4 beds \| 3 baths \| 3,560 sq.ft.	$465,000	Airbnb cash on cash: -1.26% Traditional cash on cash: 5.27% Airbnb Rental Income: $501 Traditional Rental Income: $3067 Airbnb ROI: -1.26% Traditional ROI: 5.27%
1905 Marsh Avenue Florence, SC One-story traditional home features formal living & dining rooms, den, kitchen with dishwa...	3 beds \| 2 baths \| 1,670 sq.ft.	$239,900	Airbnb cash on cash: 1.65% Traditional cash on cash: 6.48% Airbnb Rental Income: $1147 Traditional Rental Income: $1861 Airbnb ROI: 1.65% Traditional ROI: 6.48%
2502 Lakeview Dr. Florence, SC Beautiful 4 Bedroom, 2 Bath Split-Level Home with Large Fenced-In Backyard Welcome home t...	4 beds \| 2 baths \| 2,236 sq.ft.	$239,900	Airbnb cash on cash: -0.97% Traditional cash on cash: 8.72% Airbnb Rental Income: $501 Traditional Rental Income: $2427 Airbnb ROI: -0.97% Traditional ROI: 8.72%
3109 Duchess Ln. Florence, SC Welcome to the desirable Kingsgate neighborhood! This 4-bedroom home (plus a large bonus r...	4 beds \| 4 baths \| 2,856 sq.ft.	$449,900	Airbnb cash on cash: -0.72% Traditional cash on cash: 5.78% Airbnb Rental Income: $501 Traditional Rental Income: $2969 Airbnb ROI: -0.72% Traditional ROI: 5.78%
3016 Greystone Cir Florence, SC Looking for a home with plenty of room to grow? This spacious property could be exactly wh...	3 beds \| 2 baths \| 1,931 sq.ft.	$214,000	Airbnb cash on cash: 1.25% Traditional cash on cash: 7.88% Airbnb Rental Income: $1147 Traditional Rental Income: $2112 Airbnb ROI: 1.25% Traditional ROI: 7.88%
307 Fairhaven Street Florence, SC Welcome to this single story 3 bedroom, 2 bathroom home. Located in the desired West Flore...	3 beds \| 2 baths \| 1,458 sq.ft.	$249,000	Airbnb cash on cash: 1.65% Traditional cash on cash: 6% Airbnb Rental Income: $1147 Traditional Rental Income: $1791 Airbnb ROI: 1.65% Traditional ROI: 6%
900 Scriven Dr. Florence, SC Location, charm, and updatesâ¦ this one has it ALL! This inviting, updated single-story ...	4 beds \| 3 baths \| 2,339 sq.ft.	$439,000	Airbnb cash on cash: -0.81% Traditional cash on cash: 5.27% Airbnb Rental Income: $501 Traditional Rental Income: $2730 Airbnb ROI: -0.81% Traditional ROI: 5.27%
906/908 Sherwood Drive Florence, SC Brick duplex. Each side has 2 bedrooms and 1 bathroom. Large great room. Outside storage ...	N/A beds \| N/A baths \| N/A	$207,000	Airbnb cash on cash: -0.96% Traditional cash on cash: 4.63% Airbnb Rental Income: $501 Traditional Rental Income: $1327 Airbnb ROI: -0.96% Traditional ROI: 4.63%
4219 Rodanthe Cir Florence, SC Welcome home to 4219 Rodanthe Circle, located in the desirable Wedgewood neighborhood. Thi...	4 beds \| 3 baths \| 2,461 sq.ft.	$469,000	Airbnb cash on cash: -0.72% Traditional cash on cash: 4.65% Airbnb Rental Income: $501 Traditional Rental Income: $2588 Airbnb ROI: -0.72% Traditional ROI: 4.65%
851 S Dunes Dr Florence, SC Welcome to 851 S Dunes Drive, a spacious and versatile home offering over 2,300 square fee...	4 beds \| 3 baths \| 2,393 sq.ft.	$339,900	Airbnb cash on cash: -0.75% Traditional cash on cash: 6.41% Airbnb Rental Income: $501 Traditional Rental Income: $2515 Airbnb ROI: -0.75% Traditional ROI: 6.41%
1671 Lake Wateree Drive Florence, SC Immaculate brick home located in the desirable West Lakes subdivision in Florence, SC, rea...	4 beds \| 3 baths \| 3,086 sq.ft.	$399,900	Airbnb cash on cash: -1.21% Traditional cash on cash: 5.29% Airbnb Rental Income: $501 Traditional Rental Income: $2663 Airbnb ROI: -1.21% Traditional ROI: 5.29%
2137 Waverly Woods Drive Florence, SC Beautifully maintained brick home located in South Florence in Waverly Woods Subdivision. ...	4 beds \| 3 baths \| 2,106 sq.ft.	$299,900	Airbnb cash on cash: -1.09% Traditional cash on cash: 6.06% Airbnb Rental Income: $501 Traditional Rental Income: $2245 Airbnb ROI: -1.09% Traditional ROI: 6.06%
3241 Lakeshore Drive Florence, SC Discover your perfect 4000 sq-ft, lakefront sanctuary in this stunning four-bedroom, four-...	4 beds \| 5 baths \| 4,000 sq.ft.	$849,900	Airbnb cash on cash: -1.4% Traditional cash on cash: 5.01% Airbnb Rental Income: $501 Traditional Rental Income: $5299 Airbnb ROI: -1.4% Traditional ROI: 5.01%
3406 Sussex Court Florence, SC Welcome to this fabulous home and what it offers. Beautiful traditional floor plan with l...	4 beds \| 4 baths \| 3,477 sq.ft.	$439,500	Airbnb cash on cash: -1.24% Traditional cash on cash: 6.4% Airbnb Rental Income: $501 Traditional Rental Income: $3374 Airbnb ROI: -1.24% Traditional ROI: 6.4%
1007 W Palmetto St Florence, SC Step back in time with this 1933 Tudor-style landmark. This architectural treasure feature...	4 beds \| 4 baths \| 4,336 sq.ft.	$325,000	Airbnb cash on cash: -1.12% Traditional cash on cash: 10.59% Airbnb Rental Income: $501 Traditional Rental Income: $3806 Airbnb ROI: -1.12% Traditional ROI: 10.59%
959 Park Avenue Florence, SC Welcome home to this spacious one-story brick ranch in the heart of Florence. Situated on ...	3 beds \| 2 baths \| 1,987 sq.ft.	$259,900	Airbnb cash on cash: 1.18% Traditional cash on cash: 6.73% Airbnb Rental Income: $1147 Traditional Rental Income: $2128 Airbnb ROI: 1.18% Traditional ROI: 6.73%
1716 Furman Drive Florence, SC Welcome home to 1716 Furman Drive in College Park! Perfectly located in the heart of Flore...	3 beds \| 2 baths \| 1,658 sq.ft.	$255,000	Airbnb cash on cash: 1.23% Traditional cash on cash: 5.88% Airbnb Rental Income: $1147 Traditional Rental Income: $1886 Airbnb ROI: 1.23% Traditional ROI: 5.88%
3445 Claude Douglas Circle Florence, SC Located in Forest Lake West, this spacious 4-bedroom, 3.5-bath home offers approximately 2...	4 beds \| 4 baths \| 2,800 sq.ft.	$469,900	Airbnb cash on cash: -0.98% Traditional cash on cash: 5.6% Airbnb Rental Income: $501 Traditional Rental Income: $3121 Airbnb ROI: -0.98% Traditional ROI: 5.6%
2130 Woodmore Circle Florence, SC Welcome to this 3-bedroom, 2-bath home featuring a 2-car attached garage and comfortable ...	3 beds \| 2 baths \| 1,757 sq.ft.	$226,250	Airbnb cash on cash: 0.56% Traditional cash on cash: 7% Airbnb Rental Income: $1147 Traditional Rental Income: $2145 Airbnb ROI: 0.56% Traditional ROI: 7%
1460 Chandler Circle Florence, SC	3 beds \| 3 baths \| 1,904 sq.ft.	$299,000	Airbnb cash on cash: 0.36% Traditional cash on cash: 5.5% Airbnb Rental Income: $1147 Traditional Rental Income: $2213 Airbnb ROI: 0.36% Traditional ROI: 5.5%
419 Whitman Avenue Florence, SC Discover the charm of this beautifully renovated brick home located at 419 Whitman Ave, 29...	3 beds \| 2 baths \| 2,210 sq.ft.	$429,000	Airbnb cash on cash: 0.45% Traditional cash on cash: 3.18% Airbnb Rental Income: $1147 Traditional Rental Income: $1860 Airbnb ROI: 0.45% Traditional ROI: 3.18%
708 Muirfield Place Florence, SC Welcome to 708 Muirfield Place, a stunning all-brick home nestled on the water in prestigi...	4 beds \| 4 baths \| 3,809 sq.ft.	$579,500	Airbnb cash on cash: -2.3% Traditional cash on cash: 2.54% Airbnb Rental Income: $501 Traditional Rental Income: $2852 Airbnb ROI: -2.3% Traditional ROI: 2.54%
1507 Rosedale Street Florence, SC	3 beds \| 2 baths \| 1,483 sq.ft.	$249,000	Airbnb cash on cash: 1.65% Traditional cash on cash: 5.55% Airbnb Rental Income: $1147 Traditional Rental Income: $1684 Airbnb ROI: 1.65% Traditional ROI: 5.55%
1625 Sharon Road Florence, SC 3 bd 1.5 ba home located in Florence. .44 acre lot.	3 beds \| 2 baths \| 1,232 sq.ft.	$162,000	Airbnb cash on cash: 3.01% Traditional cash on cash: 8.33% Airbnb Rental Income: $1147 Traditional Rental Income: $1590 Airbnb ROI: 3.01% Traditional ROI: 8.33%
2109 Eaton Cir Florence, SC Renovated 2 years ago, 3 bedrooms, 1 /12 baths, all brick home, all new updated electric ...	3 beds \| 2 baths \| 1,154 sq.ft.	$209,900	Airbnb cash on cash: 1.82% Traditional cash on cash: 5.39% Airbnb Rental Income: $1147 Traditional Rental Income: $1479 Airbnb ROI: 1.82% Traditional ROI: 5.39%
3326 Lakeshore Drive Florence, SC Welcome home to the charm and comfort of Forest Lake living in this beautiful 4 to 5 bedro...	5 beds \| 4 baths \| 3,798 sq.ft.	$599,900	Airbnb cash on cash: N/A Traditional cash on cash: 2.86% Airbnb Rental Income: $null Traditional Rental Income: $2571 Airbnb ROI: N/A Traditional ROI: 2.86%
1244 Strada Amore #3 Florence, SC Welcome to 1244 Strada Amore! This well maintained 2-bedroom, 2-bathroom second floor cond...	2 beds \| 2 baths \| 1,475 sq.ft.	$160,000	Airbnb cash on cash: -0.56% Traditional cash on cash: 5.57% Airbnb Rental Income: $830 Traditional Rental Income: $1439 Airbnb ROI: -0.56% Traditional ROI: 5.57%
130 Mustang Rd Florence, SC 2 Brick Ranch Homes---1) Home 3/1 Super Nice inside & 1 - Brick Ranch Home 3/...	3 beds \| 1 baths \| 1,316 sq.ft.	$449,900	Airbnb cash on cash: 0.23% Traditional cash on cash: 1.63% Airbnb Rental Income: $1147 Traditional Rental Income: $1356 Airbnb ROI: 0.23% Traditional ROI: 1.63%
912 Camp Wiggins Rd. Florence, SC Enjoy the freedom of country living with NO HOA in this spaciously renovated brick home si...	3 beds \| 2 baths \| 2,028 sq.ft.	$289,000	Airbnb cash on cash: 0.91% Traditional cash on cash: 5.36% Airbnb Rental Income: $1147 Traditional Rental Income: $1979 Airbnb ROI: 0.91% Traditional ROI: 5.36%
1013 Via Salvatore Florence, SC Welcome to this beautifully maintained home tucked within a charming, low-maintenance comm...	5 beds \| 3 baths \| 263 sq.ft.	$339,900	Airbnb cash on cash: N/A Traditional cash on cash: 5.72% Airbnb Rental Income: $null Traditional Rental Income: $2419 Airbnb ROI: N/A Traditional ROI: 5.72%
3155 S Cashua Drive, #11 Florence, SC WELCOME HOME to this cozy and beautiful two bedroom, two bath condo in Pine Lakes Subdivis...	2 beds \| 2 baths \| 1,200 sq.ft.	$129,900	Airbnb cash on cash: 0.82% Traditional cash on cash: 6.46% Airbnb Rental Income: $830 Traditional Rental Income: $1208 Airbnb ROI: 0.82% Traditional ROI: 6.46%
2129 Kristens Channel Florence, SC Lakefront living at its finest! Morning light reflecting across the tranquil waters of For...	5 beds \| 3 baths \| 3,626 sq.ft.	$784,900	Airbnb cash on cash: N/A Traditional cash on cash: 1.84% Airbnb Rental Income: $null Traditional Rental Income: $2586 Airbnb ROI: N/A Traditional ROI: 1.84%
1819 Hazel Dr. Florence, SC Welcome to this beautifully remodeled open-concept home offering space, flexibility, and m...	4 beds \| 2 baths \| 2,232 sq.ft.	$423,900	Airbnb cash on cash: -1.4% Traditional cash on cash: 1.96% Airbnb Rental Income: $501 Traditional Rental Income: $1561 Airbnb ROI: -1.4% Traditional ROI: 1.96%
313 S Gaillard St Florence, SC Three bedroom oand one bathroom home in Florence, SC is seconds from McLeod Hospital. With...	3 beds \| 1 baths \| 1,074 sq.ft.	$165,000	Airbnb cash on cash: 2.99% Traditional cash on cash: 6.99% Airbnb Rental Income: $1147 Traditional Rental Income: $1396 Airbnb ROI: 2.99% Traditional ROI: 6.99%
2220 Oakwood Lane APT A8 Florence, SC Welcome to your new home. Nestled within the quiet Foxboro Subdivision this beautiful 2 be...	2 beds \| 2 baths \| 1,088 sq.ft.	$125,000	Airbnb cash on cash: 1.84% Traditional cash on cash: 9.91% Airbnb Rental Income: $830 Traditional Rental Income: $1475 Airbnb ROI: 1.84% Traditional ROI: 9.91%
1451 Gregg Ave. Florence, SC A lovely little bungalow on a large corner lot in W Florence with lots of quaint charm. Co...	3 beds \| 1 baths \| 990 sq.ft.	$155,500	Airbnb cash on cash: 2.81% Traditional cash on cash: 8.36% Airbnb Rental Income: $1147 Traditional Rental Income: $1591 Airbnb ROI: 2.81% Traditional ROI: 8.36%
2797 Leola Hill Drive Florence, SC Nestled on the outskirts of Florence, SC, this beautifully updated 3-bedroom, 2-full bathr...	3 beds \| 2 baths \| 1,680 sq.ft.	$189,000	Airbnb cash on cash: 2.54% Traditional cash on cash: 8.01% Airbnb Rental Income: $1147 Traditional Rental Income: $1750 Airbnb ROI: 2.54% Traditional ROI: 8.01%
2207 S Vance Drive Florence, SC Welcome to this inviting 3-bedroom, 2-bathroom home situated in the heart of Florence, SC....	3 beds \| 2 baths \| 1,620 sq.ft.	$249,000	Airbnb cash on cash: 1.61% Traditional cash on cash: 6.43% Airbnb Rental Income: $1147 Traditional Rental Income: $1901 Airbnb ROI: 1.61% Traditional ROI: 6.43%
404 W Vista St. Florence, SC New construction two story home for sale in the city of Florence, S.C. Nice three bedrooms...	3 beds \| 2 baths \| 1,600 sq.ft.	$239,500	Airbnb cash on cash: 1.85% Traditional cash on cash: 6.66% Airbnb Rental Income: $1147 Traditional Rental Income: $1856 Airbnb ROI: 1.85% Traditional ROI: 6.66%
7417 E National Cemetery Road Florence, SC Majestic Comfort Meets Modern Design. Step into this beautifully crafted 3-bedroom home f...	3 beds \| 2 baths \| 1,730 sq.ft.	$319,500	Airbnb cash on cash: 1.04% Traditional cash on cash: 5.38% Airbnb Rental Income: $1147 Traditional Rental Income: $2071 Airbnb ROI: 1.04% Traditional ROI: 5.38%

Real Estate investment in Florence, SC

There are 240 properties for sale in the city of Florence . The median list price in Florence is $282,335 and the average price per square foot is $135. In April 2026, the average monthly cash on cash return in Florence is 6.00%. The average monthly rental income in Florence is $2,110.

Florence, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 240 investment properties available for sale in Florence.

In 2026, the best neighborhood to buy investment property is Florence.

The ROI for Long-Term is higher than the Short-Term in Florence with average rental income of $2,110.

Your search for investment property begins and ends here

Investment Property for Sale in Florence, SC

3207 Lakeshore Drive

Florence, SC

4 beds | 3 baths | 3,560 sq.ft.

$465,000

Airbnb cash on cash: -1.26%

Traditional cash on cash: 5.27%

Airbnb Rental Income: $501

Traditional Rental Income: $3067

Airbnb ROI: -1.26%

Traditional ROI: 5.27%

1905 Marsh Avenue

Florence, SC

3 beds | 2 baths | 1,670 sq.ft.

$239,900

Airbnb cash on cash: 1.65%

Traditional cash on cash: 6.48%

Airbnb Rental Income: $1147

Traditional Rental Income: $1861

Airbnb ROI: 1.65%

Traditional ROI: 6.48%

2502 Lakeview Dr.

Florence, SC

4 beds | 2 baths | 2,236 sq.ft.

$239,900

Airbnb cash on cash: -0.97%

Traditional cash on cash: 8.72%

Airbnb Rental Income: $501

Traditional Rental Income: $2427

Airbnb ROI: -0.97%

Traditional ROI: 8.72%

3109 Duchess Ln.

Florence, SC

4 beds | 4 baths | 2,856 sq.ft.

$449,900

Airbnb cash on cash: -0.72%

Traditional cash on cash: 5.78%

Airbnb Rental Income: $501

Traditional Rental Income: $2969

Airbnb ROI: -0.72%

Traditional ROI: 5.78%

3016 Greystone Cir

Florence, SC

3 beds | 2 baths | 1,931 sq.ft.

$214,000

Airbnb cash on cash: 1.25%

Traditional cash on cash: 7.88%

Airbnb Rental Income: $1147

Traditional Rental Income: $2112

Airbnb ROI: 1.25%

Traditional ROI: 7.88%

307 Fairhaven Street

Florence, SC

3 beds | 2 baths | 1,458 sq.ft.

$249,000

Airbnb cash on cash: 1.65%

Traditional cash on cash: 6%

Airbnb Rental Income: $1147

Traditional Rental Income: $1791

Airbnb ROI: 1.65%

Traditional ROI: 6%

900 Scriven Dr.

Florence, SC

4 beds | 3 baths | 2,339 sq.ft.

$439,000

Airbnb cash on cash: -0.81%

Traditional cash on cash: 5.27%

Airbnb Rental Income: $501

Traditional Rental Income: $2730

Airbnb ROI: -0.81%

Traditional ROI: 5.27%

906/908 Sherwood Drive

Florence, SC

N/A beds | N/A baths | N/A

$207,000

Airbnb cash on cash: -0.96%

Traditional cash on cash: 4.63%

Airbnb Rental Income: $501

Traditional Rental Income: $1327

Airbnb ROI: -0.96%