Real Estate Investment Properties for Sale in Lake City, SC

Looking for investment property in Lake City, SC with high ROI ?

Explore a variety of short-term homes & houses in Lake City, SC. Invest wisely with VRBO & Lake City, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Lake City, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
520 E Main St LAKE CITY, SC Welcome to peaceful living and stylish functionality! This 3 bedroom, 2 bath home is brimm...	3 beds \| 2 baths \| 2,620 sq.ft.	$329,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.24% Airbnb Rental Income: $null Traditional Rental Income: $2662 Airbnb ROI: N/A Traditional ROI: 6.24%
615 E Main St LAKE CITY, SC Well-built brick home that has been tastefully remodeled. The kitchen features new cabinet...	3 beds \| 2 baths \| 3,040 sq.ft.	$315,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.95% Airbnb Rental Income: $null Traditional Rental Income: $2026 Airbnb ROI: N/A Traditional ROI: 4.95%
1484 Fitch Rd LAKE CITY, SC Luxurious 3-Bedroom Retreat on 3 Lush Acres â Your Private Oasis Awaits! Escape to elega...	3 beds \| 2 baths \| 4,089 sq.ft.	$584,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.61% Airbnb Rental Income: $null Traditional Rental Income: $2207 Airbnb ROI: N/A Traditional ROI: 2.61%
3017 Barrineau Rd LAKE CITY, SC Rare find in the heart of Barrineau! Charming 3 bed, 2 bath home in a quaint small town! T...	3 beds \| 2 baths \| 1,344 sq.ft.	$229,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.74% Airbnb Rental Income: $null Traditional Rental Income: $1778 Airbnb ROI: N/A Traditional ROI: 6.74%
1309 N Matthews Rd LAKE CITY, SC SOLD "AS IS". This beautiful property has 4.29 acres. The downstairs is heated and coole...	2 beds \| 2 baths \| 1,659 sq.ft.	$207,000	Airbnb cash on cash: 0.54% Traditional cash on cash: 8.96% Airbnb Rental Income: $834 Traditional Rental Income: $2159 Airbnb ROI: 0.54% Traditional ROI: 8.96%
722 Twin Oaks Cir LAKE CITY, SC NEW LISTING ALERT! 722 Twin Oaks Circle Lake City, SC $225,000\| 3 Bedrooms \| 2 1/2 Bat...	3 beds \| 2 baths \| 1,603 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.95% Airbnb Rental Income: $null Traditional Rental Income: $2535 Airbnb ROI: N/A Traditional ROI: 8.95%
52 Acres-TBD Vox Hwy LAKE CITY, SC 52 Acres-TBD Vox Hwy, LAKE CITY, SC 29560 \| Other	N/A beds \| N/A baths \| N/A	$221,000	Airbnb cash on cash: N/A Traditional cash on cash: 2.01% Airbnb Rental Income: $null Traditional Rental Income: $843 Airbnb ROI: N/A Traditional ROI: 2.01%
217 Smith St LAKE CITY, SC 217 Smith St, LAKE CITY, SC 29560 \| Single Family Residential	4 beds \| 2 baths \| 2,216 sq.ft.	$229,000	Airbnb cash on cash: N/A Traditional cash on cash: 8.83% Airbnb Rental Income: $null Traditional Rental Income: $2346 Airbnb ROI: N/A Traditional ROI: 8.83%
900 S Morris St LAKE CITY, SC 900 S Morris St, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 1,549 sq.ft.	$160,000	Airbnb cash on cash: N/A Traditional cash on cash: 11.31% Airbnb Rental Income: $null Traditional Rental Income: $2061 Airbnb ROI: N/A Traditional ROI: 11.31%
116 S Second Ave LAKE CITY, SC 116 S Second Ave, LAKE CITY, SC 29560 \| Single Family Residential	4 beds \| 2 baths \| 3,510 sq.ft.	$299,000	Airbnb cash on cash: N/A Traditional cash on cash: 6.17% Airbnb Rental Income: $null Traditional Rental Income: $2272 Airbnb ROI: N/A Traditional ROI: 6.17%
3728 W Turbeville Hwy LAKE CITY, SC 3728 W Turbeville Hwy, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 2,100 sq.ft.	$450,000	Airbnb cash on cash: N/A Traditional cash on cash: 3.22% Airbnb Rental Income: $null Traditional Rental Income: $2111 Airbnb ROI: N/A Traditional ROI: 3.22%
310 Elm St LAKE CITY, SC 310 Elm St, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 1,176 sq.ft.	$155,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.43% Airbnb Rental Income: $null Traditional Rental Income: $1871 Airbnb ROI: N/A Traditional ROI: 10.43%
220 Brantley St LAKE CITY, SC 220 Brantley St, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 2,578 sq.ft.	$323,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.44% Airbnb Rental Income: $null Traditional Rental Income: $2221 Airbnb ROI: N/A Traditional ROI: 5.44%
506 Taylor St LAKE CITY, SC 506 Taylor St, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 1 baths \| 1,456 sq.ft.	$137,900	Airbnb cash on cash: N/A Traditional cash on cash: 11.14% Airbnb Rental Income: $null Traditional Rental Income: $1776 Airbnb ROI: N/A Traditional ROI: 11.14%
739 & 741 Jones Rd LAKE CITY, SC 739 & 741 Jones Rd, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 2,500 sq.ft.	$3,500,000	Airbnb cash on cash: N/A Traditional cash on cash: -0.93% Airbnb Rental Income: $null Traditional Rental Income: $2157 Airbnb ROI: N/A Traditional ROI: -0.93%
5.9AC W Main St LAKE CITY, SC 5.9AC W Main St, LAKE CITY, SC 29560 \| Other	N/A beds \| N/A baths \| N/A	$109,000	Airbnb cash on cash: N/A Traditional cash on cash: 5.53% Airbnb Rental Income: $null Traditional Rental Income: $843 Airbnb ROI: N/A Traditional ROI: 5.53%
213 Creek Dr LAKE CITY, SC 213 Creek Dr, LAKE CITY, SC 29560 \| Single Family Residential	2 beds \| 1 baths \| 1,389 sq.ft.	$170,000	Airbnb cash on cash: 0.98% Traditional cash on cash: 7.06% Airbnb Rental Income: $834 Traditional Rental Income: $1492 Airbnb ROI: 0.98% Traditional ROI: 7.06%
528 Azalea Dr LAKE CITY, SC 528 Azalea Dr, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 1,472 sq.ft.	$225,000	Airbnb cash on cash: N/A Traditional cash on cash: 7.89% Airbnb Rental Income: $null Traditional Rental Income: $2108 Airbnb ROI: N/A Traditional ROI: 7.89%
532 Palm Cir LAKE CITY, SC 532 Palm Cir, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 1,000 sq.ft.	$155,000	Airbnb cash on cash: N/A Traditional cash on cash: 10.02% Airbnb Rental Income: $null Traditional Rental Income: $1811 Airbnb ROI: N/A Traditional ROI: 10.02%
609 E Main St LAKE CITY, SC 609 E Main St, LAKE CITY, SC 29560 \| Single Family Residential	3 beds \| 2 baths \| 4,249 sq.ft.	$229,900	Airbnb cash on cash: N/A Traditional cash on cash: 4.51% Airbnb Rental Income: $null Traditional Rental Income: $1414 Airbnb ROI: N/A Traditional ROI: 4.51%

Real Estate investment in Lake-city, SC

There are 21 properties for sale in the city of Lake City . The median list price in Lake City is $259,900 and the average price per square foot is $139. In March 2026, the average monthly cash on cash return in Lake City is 12.00%. The average monthly rental income in Lake City is $1,634.

Lake-city, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 21 investment properties available for sale in Lake-city.

In 2026, the best neighborhood to buy investment property is LAKE CITY.

The ROI for Short-Term is higher than the Long-Term in Lake-city with average rental income of $834.

Your search for investment property begins and ends here

Investment Property for Sale in Lake City, SC

520 E Main St

LAKE CITY, SC

3 beds | 2 baths | 2,620 sq.ft.

$329,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.24%

Airbnb Rental Income: $null

Traditional Rental Income: $2662

Airbnb ROI: N/A

Traditional ROI: 6.24%

615 E Main St

LAKE CITY, SC

3 beds | 2 baths | 3,040 sq.ft.

$315,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.95%

Airbnb Rental Income: $null

Traditional Rental Income: $2026

Airbnb ROI: N/A

Traditional ROI: 4.95%

1484 Fitch Rd

LAKE CITY, SC

3 beds | 2 baths | 4,089 sq.ft.

$584,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.61%

Airbnb Rental Income: $null

Traditional Rental Income: $2207

Airbnb ROI: N/A

Traditional ROI: 2.61%

3017 Barrineau Rd

LAKE CITY, SC

3 beds | 2 baths | 1,344 sq.ft.

$229,000

Airbnb cash on cash: N/A

Traditional cash on cash: 6.74%

Airbnb Rental Income: $null

Traditional Rental Income: $1778

Airbnb ROI: N/A

Traditional ROI: 6.74%

1309 N Matthews Rd

LAKE CITY, SC

2 beds | 2 baths | 1,659 sq.ft.

$207,000

Airbnb cash on cash: 0.54%

Traditional cash on cash: 8.96%

Airbnb Rental Income: $834

Traditional Rental Income: $2159

Airbnb ROI: 0.54%

Traditional ROI: 8.96%

722 Twin Oaks Cir

LAKE CITY, SC

3 beds | 2 baths | 1,603 sq.ft.

$225,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.95%

Airbnb Rental Income: $null

Traditional Rental Income: $2535

Airbnb ROI: N/A

Traditional ROI: 8.95%

52 Acres-TBD Vox Hwy

LAKE CITY, SC

N/A beds | N/A baths | N/A

$221,000

Airbnb cash on cash: N/A

Traditional cash on cash: 2.01%

Airbnb Rental Income: $null

Traditional Rental Income: $843

Airbnb ROI: N/A

Traditional ROI: 2.01%

217 Smith St

LAKE CITY, SC

4 beds | 2 baths | 2,216 sq.ft.

$229,000

Airbnb cash on cash: N/A

Traditional cash on cash: 8.83%

Airbnb Rental Income: $null

Traditional Rental Income: $2346

Airbnb ROI: N/A