Real Estate Investment Properties for Sale in Salem, SC

Looking for investment property in Salem, SC with high ROI ?

Explore a variety of short-term homes & houses in Salem, SC. Invest wisely with VRBO & Salem, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Salem, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
130 Green Briar Circle Salem, SC For a private showing or for any questions please text or Call Bob Morgan at 864-915-HOME(...	5 beds \| 4 baths \| N/A	$500,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.44% Airbnb Rental Income: $null Traditional Rental Income: $2715 Airbnb ROI: N/A Traditional ROI: 4.44%
21 Anchorage Lane Salem, SC Set within the premier gated community of Keowee Key, where lake living meets the foothill...	4 beds \| 3 baths \| N/A	$390,000	Airbnb cash on cash: 0.06% Traditional cash on cash: 4.7% Airbnb Rental Income: $1456 Traditional Rental Income: $2720 Airbnb ROI: 0.06% Traditional ROI: 4.7%
321 Coveview Court Salem, SC Start enjoying Lake Life from this MOSTLY FURNISHED KEOWEE KEY MARINA VILLAS CONDO located...	2 beds \| 3 baths \| 1,750 sq.ft.	$439,900	Airbnb cash on cash: 0.23% Traditional cash on cash: 2.15% Airbnb Rental Income: $1480 Traditional Rental Income: $1839 Airbnb ROI: 0.23% Traditional ROI: 2.15%
131 Harbor Lights Drive Salem, SC Enjoy the best of Keowee Key living in this spacious 3-bedroom townhome with loft, perfect...	3 beds \| 2 baths \| 1,570 sq.ft.	$355,000	Airbnb cash on cash: -1.59% Traditional cash on cash: 0.82% Airbnb Rental Income: $1149 Traditional Rental Income: $1574 Airbnb ROI: -1.59% Traditional ROI: 0.82%
21 Starboard Tack Drive Salem, SC Welcome to 21 Starboard Tack, a 3BR/3BA home located in the highly sought-after gated wate...	3 beds \| 3 baths \| N/A	$570,000	Airbnb cash on cash: -1.04% Traditional cash on cash: 1.41% Airbnb Rental Income: $1149 Traditional Rental Income: $2074 Airbnb ROI: -1.04% Traditional ROI: 1.41%
202 Hearthstone Way Salem, SC Welcome to 202 Hearthstone Way at The Cliffs at Keowee Falls. Magnificent mountain and lak...	4 beds \| 6 baths \| 4,900 sq.ft.	$2,599,000	Airbnb cash on cash: -0.87% Traditional cash on cash: 1.11% Airbnb Rental Income: $1456 Traditional Rental Income: $5807 Airbnb ROI: -0.87% Traditional ROI: 1.11%
3 Maritime Drive Salem, SC New Price. "Motivated Sellers!" Nestled on the Northside of the serene lake-community of K...	3 beds \| 3 baths \| 3,030 sq.ft.	$597,500	Airbnb cash on cash: -0.9% Traditional cash on cash: 2.19% Airbnb Rental Income: $1149 Traditional Rental Income: $2491 Airbnb ROI: -0.9% Traditional ROI: 2.19%
205 Elliot Drive Salem, SC Investment or flip opportunity on this custom designed, three bedroom, two full bath class...	3 beds \| 2 baths \| 1,344 sq.ft.	$188,000	Airbnb cash on cash: 2.21% Traditional cash on cash: 7.45% Airbnb Rental Income: $1149 Traditional Rental Income: $1704 Airbnb ROI: 2.21% Traditional ROI: 7.45%
20 Fair Wind Drive Salem, SC The Keowee Lake Life is waiting for you and now is your time! Welcome to this beautifully...	3 beds \| 3 baths \| 1,804 sq.ft.	$385,000	Airbnb cash on cash: 0.38% Traditional cash on cash: 3.02% Airbnb Rental Income: $1149 Traditional Rental Income: $1723 Airbnb ROI: 0.38% Traditional ROI: 3.02%
275 Jocassee Lake Road Salem, SC Nestled perfectly between the serene waters of Lake Jocassee and Lake Keowee, this charmin...	2 beds \| 2 baths \| 1,222 sq.ft.	$475,000	Airbnb cash on cash: 0.85% Traditional cash on cash: 2.25% Airbnb Rental Income: $1480 Traditional Rental Income: $1669 Airbnb ROI: 0.85% Traditional ROI: 2.25%
11 Captain Lane Salem, SC Exceptional Price Per Square Foot in Keowee Key - Room to Renovate and Make It Your Own! W...	3 beds \| 2 baths \| N/A	$449,000	Airbnb cash on cash: -1.35% Traditional cash on cash: 2.88% Airbnb Rental Income: $1149 Traditional Rental Income: $2545 Airbnb ROI: -1.35% Traditional ROI: 2.88%
272 Jocassee Ridge Way Salem, SC MAGNIFICANT MOUNTAIN VIEWS from almost every room in the home. Located on a 1.55 acre lot ...	4 beds \| 5 baths \| 4,283 sq.ft.	$699,900	Airbnb cash on cash: -0.37% Traditional cash on cash: 3.81% Airbnb Rental Income: $1456 Traditional Rental Income: $3751 Airbnb ROI: -0.37% Traditional ROI: 3.81%
N-35A Meadow View Way Salem, SC Are you Searching for that perfect mountain view home surrounded by Mother Nature's gifts ...	4 beds \| 4 baths \| N/A	$1,095,077	Airbnb cash on cash: -0.71% Traditional cash on cash: 1.49% Airbnb Rental Income: $1456 Traditional Rental Income: $3261 Airbnb ROI: -0.71% Traditional ROI: 1.49%
580 Old Chapman Bridge Road Salem, SC NEW waterfront home located in the Cliffs at Keowee Falls - Northpoint on a gently sloping...	5 beds \| 5 baths \| 5,839 sq.ft.	$3,600,000	Airbnb cash on cash: N/A Traditional cash on cash: -0.34% Airbnb Rental Income: $null Traditional Rental Income: $4236 Airbnb ROI: N/A Traditional ROI: -0.34%
605 River Birch Way Salem, SC Discover refined mountain-lake living in The Retreat enclave of The Cliffs at Keowee Falls...	4 beds \| 4 baths \| 2,421 sq.ft.	$1,179,000	Airbnb cash on cash: -0.72% Traditional cash on cash: 1.4% Airbnb Rental Income: $1456 Traditional Rental Income: $3339 Airbnb ROI: -0.72% Traditional ROI: 1.4%
491 Tall Ship Drive unit: 326 Salem, SC Welcome to Tall Ship Building 491 Unit 326, a beautifully updated corner condo with stunni...	2 beds \| 2 baths \| 1,460 sq.ft.	$424,900	Airbnb cash on cash: -0.17% Traditional cash on cash: 3% Airbnb Rental Income: $1480 Traditional Rental Income: $2305 Airbnb ROI: -0.17% Traditional ROI: 3%
703 Timberbrook Trail Salem, SC Welcome to an extraordinary retreat in the prestigious Cliffs at Keowee Falls, where timel...	5 beds \| 4 baths \| 3,480 sq.ft.	$1,595,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.46% Airbnb Rental Income: $null Traditional Rental Income: $3408 Airbnb ROI: N/A Traditional ROI: 0.46%
259 W Main Street Salem, SC Experience peaceful country living with convenience and charm in this meticulously maintai...	3 beds \| 2 baths \| 2,176 sq.ft.	$295,000	Airbnb cash on cash: 1.32% Traditional cash on cash: 6.06% Airbnb Rental Income: $1149 Traditional Rental Income: $2086 Airbnb ROI: 1.32% Traditional ROI: 6.06%
30 Gulf Stream Lane Salem, SC Originally constructed in 2002 in Keowee Key as a small home on one site for a young famil...	4 beds \| 5 baths \| N/A	$1,080,000	Airbnb cash on cash: -0.4% Traditional cash on cash: 3.58% Airbnb Rental Income: $1456 Traditional Rental Income: $5016 Airbnb ROI: -0.4% Traditional ROI: 3.58%
213 Shipmaster Drive Salem, SC Welcome to 213 Shipmaster Drive, a beautifully maintained home nestled on a 1.6-acre estat...	4 beds \| 4 baths \| 3,130 sq.ft.	$739,000	Airbnb cash on cash: 0.12% Traditional cash on cash: 3.4% Airbnb Rental Income: $1456 Traditional Rental Income: $3284 Airbnb ROI: 0.12% Traditional ROI: 3.4%
400-1 Captains Walk Circle Salem, SC Live the Lake Keowee Resort Lifestyle here at 400 Captains Walk Circle, Unit 1 - Keowee Ke...	2 beds \| 1 baths \| 768 sq.ft.	$219,000	Airbnb cash on cash: 3.2% Traditional cash on cash: 4.53% Airbnb Rental Income: $1480 Traditional Rental Income: $1320 Airbnb ROI: 3.2% Traditional ROI: 4.53%
18 Mainsail Drive Salem, SC Welcome to the gated community of Keowee Key. Enjoy the 4 seasons with close proximity to ...	3 beds \| 3 baths \| N/A	$615,000	Airbnb cash on cash: 0% Traditional cash on cash: 3.04% Airbnb Rental Income: $1149 Traditional Rental Income: $2518 Airbnb ROI: 0% Traditional ROI: 3.04%
505 Long Reach Drive Salem, SC Welcome to 505 Long Reach Drive, a home that feels like it was made just for you, where cl...	4 beds \| 3 baths \| N/A	$650,000	Airbnb cash on cash: -0.03% Traditional cash on cash: 2.84% Airbnb Rental Income: $1456 Traditional Rental Income: $2765 Airbnb ROI: -0.03% Traditional ROI: 2.84%
338 Long Cove Trail Salem, SC Rare Find Built in 2023 Lake Keowee Waterfront Custom Home on the MAIN CHANNEL with a PRIV...	4 beds \| 4 baths \| 3,415 sq.ft.	$2,299,900	Airbnb cash on cash: -1.01% Traditional cash on cash: 0.1% Airbnb Rental Income: $1456 Traditional Rental Income: $3373 Airbnb ROI: -1.01% Traditional ROI: 0.1%
207 S Reach Lane Salem, SC Here is your opportunity to live on Lake Keowee. Home is located in the South Reach enclav...	2 beds \| 2 baths \| 3,192 sq.ft.	$999,000	Airbnb cash on cash: -0.17% Traditional cash on cash: 0.94% Airbnb Rental Income: $1480 Traditional Rental Income: $2076 Airbnb ROI: -0.17% Traditional ROI: 0.94%
487 Tall Ship Drive unit: 121 Salem, SC Start enjoying Lake Life from this FURNISHED KEOWEE KEY TALL SHIP CONDO located in the Cut...	2 beds \| 2 baths \| 1,462 sq.ft.	$349,900	Airbnb cash on cash: 0.76% Traditional cash on cash: 4.26% Airbnb Rental Income: $1480 Traditional Rental Income: $2197 Airbnb ROI: 0.76% Traditional ROI: 4.26%
48 Commodore Drive Salem, SC Welcome to 48 Commodore Drive in Salem, South Carolina, a well-appointed home offering fle...	3 beds \| 3 baths \| N/A	$449,999	Airbnb cash on cash: 0.19% Traditional cash on cash: 4.05% Airbnb Rental Income: $1149 Traditional Rental Income: $2392 Airbnb ROI: 0.19% Traditional ROI: 4.05%
320 Knollwood Drive Salem, SC Experience the pinnacle of waterfront living in this custom-built masterpiece, perfectly p...	5 beds \| 5 baths \| N/A	$3,800,000	Airbnb cash on cash: N/A Traditional cash on cash: -0.28% Airbnb Rental Income: $null Traditional Rental Income: $4688 Airbnb ROI: N/A Traditional ROI: -0.28%
9 Anchorage Lane Salem, SC Completely updated and move-in ready, this stunning home is ideally located in the heart o...	3 beds \| 3 baths \| 2,557 sq.ft.	$725,000	Airbnb cash on cash: -0.26% Traditional cash on cash: 2.32% Airbnb Rental Income: $1149 Traditional Rental Income: $2513 Airbnb ROI: -0.26% Traditional ROI: 2.32%
102 Jocassee Falls Road Salem, SC Inviting Mountain Retreat Near Lake Jocassee - STR Friendly Discover privacy, comfort, and...	4 beds \| 2 baths \| 2,234 sq.ft.	$699,000	Airbnb cash on cash: -0.61% Traditional cash on cash: 1.45% Airbnb Rental Income: $1456 Traditional Rental Income: $2363 Airbnb ROI: -0.61% Traditional ROI: 1.45%
4 Buoy Court Salem, SC The Keowee Lake Life is waiting for you and now is your time. Welcome to this gorgeous ho...	4 beds \| 3 baths \| 3,441 sq.ft.	$675,000	Airbnb cash on cash: 0.14% Traditional cash on cash: 2.46% Airbnb Rental Income: $1456 Traditional Rental Income: $2484 Airbnb ROI: 0.14% Traditional ROI: 2.46%
12 Yeoman Lane Salem, SC An extraordinary pairing of golf course views and waterfront living on Lake Keowee within ...	4 beds \| 3 baths \| 4,079 sq.ft.	$1,250,000	Airbnb cash on cash: -0.36% Traditional cash on cash: 1.19% Airbnb Rental Income: $1456 Traditional Rental Income: $2826 Airbnb ROI: -0.36% Traditional ROI: 1.19%
316 S Reach Lane Salem, SC Imagine a place where the ripples of sparkling Lake Keowee waters and peaks of the majesti...	4 beds \| 4 baths \| 4,316 sq.ft.	$1,850,000	Airbnb cash on cash: -0.75% Traditional cash on cash: 0.84% Airbnb Rental Income: $1456 Traditional Rental Income: $3750 Airbnb ROI: -0.75% Traditional ROI: 0.84%
101 Serenity Drive Salem, SC Experience the ease of lakefront living on Lake Keowee in this beautifully designed low-ma...	3 beds \| 3 baths \| N/A	$1,385,000	Airbnb cash on cash: -0.7% Traditional cash on cash: 0.64% Airbnb Rental Income: $1149 Traditional Rental Income: $2492 Airbnb ROI: -0.7% Traditional ROI: 0.64%
709 Hemlock Court Salem, SC New construction home to be completed May 2026 offering boat slip access to Lake Keowee. T...	4 beds \| 4 baths \| 4,005 sq.ft.	$1,849,000	Airbnb cash on cash: -0.46% Traditional cash on cash: 0.85% Airbnb Rental Income: $1456 Traditional Rental Income: $3274 Airbnb ROI: -0.46% Traditional ROI: 0.85%
7 Divot Landing Salem, SC LIVE WHERE YOU PLAY! Discover the perfect home for an active, amenity-rich lifestyle in th...	3 beds \| 3 baths \| 2,393 sq.ft.	$700,000	Airbnb cash on cash: -0.54% Traditional cash on cash: 1.69% Airbnb Rental Income: $1149 Traditional Rental Income: $2223 Airbnb ROI: -0.54% Traditional ROI: 1.69%
519 Tall Ship Drive unit: 119 Salem, SC Charming Lakeview Condo in Amenity-Rich Keowee Key! Welcome to your perfect lakeside retre...	2 beds \| 4 baths \| N/A	$359,900	Airbnb cash on cash: 0.57% Traditional cash on cash: 8.42% Airbnb Rental Income: $1480 Traditional Rental Income: $3695 Airbnb ROI: 0.57% Traditional ROI: 8.42%
311 Sunset Ridge Way Salem, SC Exceptional Blue Ridge Mountain Retreat with Lake Keowee Boat Slip. 311 Sunset Ridge Way o...	5 beds \| 7 baths \| 5,298 sq.ft.	$2,850,000	Airbnb cash on cash: N/A Traditional cash on cash: 0.64% Airbnb Rental Income: $null Traditional Rental Income: $6395 Airbnb ROI: N/A Traditional ROI: 0.64%
603 Tamassee Ridge Way Salem, SC MOUNTIAN VIEWS FOR MILES! Welcome to this 5 bedroom, 4 1/2 bath home located in the gated ...	5 beds \| 5 baths \| 4,071 sq.ft.	$967,500	Airbnb cash on cash: N/A Traditional cash on cash: 2.24% Airbnb Rental Income: $null Traditional Rental Income: $3321 Airbnb ROI: N/A Traditional ROI: 2.24%
26 Marina Village Way Salem, SC Set in the amenity-rich community of Keowee Key, this inviting waterfront home blends clas...	3 beds \| 4 baths \| 3,510 sq.ft.	$1,450,000	Airbnb cash on cash: -0.89% Traditional cash on cash: 1.11% Airbnb Rental Income: $1149 Traditional Rental Income: $3464 Airbnb ROI: -0.89% Traditional ROI: 1.11%

Real Estate investment in Salem, SC

There are 53 properties for sale in the city of Salem . The median list price in Salem is $284,900 and the average price per square foot is $139. In April 2026, the average monthly cash on cash return in Salem is 2.00%. The average monthly rental income in Salem is $2,098.

Salem, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 53 investment properties available for sale in Salem.

In 2026, the best neighborhood to buy investment property is Salem.

The ROI for Short-Term is higher than the Long-Term in Salem with average rental income of $1,456.

Your search for investment property begins and ends here

Investment Property for Sale in Salem, SC

130 Green Briar Circle

Salem, SC

5 beds | 4 baths | N/A

$500,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.44%

Airbnb Rental Income: $null

Traditional Rental Income: $2715

Airbnb ROI: N/A

Traditional ROI: 4.44%

21 Anchorage Lane

Salem, SC

4 beds | 3 baths | N/A

$390,000

Airbnb cash on cash: 0.06%

Traditional cash on cash: 4.7%

Airbnb Rental Income: $1456

Traditional Rental Income: $2720

Airbnb ROI: 0.06%

Traditional ROI: 4.7%

321 Coveview Court

Salem, SC

2 beds | 3 baths | 1,750 sq.ft.

$439,900

Airbnb cash on cash: 0.23%

Traditional cash on cash: 2.15%

Airbnb Rental Income: $1480

Traditional Rental Income: $1839

Airbnb ROI: 0.23%

Traditional ROI: 2.15%

131 Harbor Lights Drive

Salem, SC

3 beds | 2 baths | 1,570 sq.ft.

$355,000

Airbnb cash on cash: -1.59%

Traditional cash on cash: 0.82%

Airbnb Rental Income: $1149

Traditional Rental Income: $1574

Airbnb ROI: -1.59%

Traditional ROI: 0.82%

21 Starboard Tack Drive

Salem, SC

3 beds | 3 baths | N/A

$570,000

Airbnb cash on cash: -1.04%

Traditional cash on cash: 1.41%

Airbnb Rental Income: $1149

Traditional Rental Income: $2074

Airbnb ROI: -1.04%

Traditional ROI: 1.41%

202 Hearthstone Way

Salem, SC

4 beds | 6 baths | 4,900 sq.ft.

$2,599,000

Airbnb cash on cash: -0.87%

Traditional cash on cash: 1.11%

Airbnb Rental Income: $1456

Traditional Rental Income: $5807

Airbnb ROI: -0.87%

Traditional ROI: 1.11%

3 Maritime Drive

Salem, SC

3 beds | 3 baths | 3,030 sq.ft.

$597,500

Airbnb cash on cash: -0.9%

Traditional cash on cash: 2.19%

Airbnb Rental Income: $1149

Traditional Rental Income: $2491

Airbnb ROI: -0.9%

Traditional ROI: 2.19%

205 Elliot Drive

Salem, SC

3 beds | 2 baths | 1,344 sq.ft.

$188,000

Airbnb cash on cash: 2.21%

Traditional cash on cash: 7.45%

Airbnb Rental Income: $1149

Traditional Rental Income: $1704

Airbnb ROI: 2.21%