Real Estate Investment Properties for Sale in Santee, SC

Looking for investment property in Santee, SC with high ROI ?

Explore a variety of short-term homes & houses in Santee, SC. Invest wisely with VRBO & Santee, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Single Family Homes for Sale in Santee, SC

Search for Single Family Residential for Sale in Santee, South Carolina. Browse all of Mashvisor’s Single Family Residential listings and other investment property types including Single Family Homes, Multi Family Homes, Condos, Townhouses and Other Homes.

Showing 22 Single Family Residential listings of over 500,000 total investment properties for sale. Visit Mashvisor.com to all investment properties.

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
370 Chapel Creek Drive Santee, SC Welcome to 370 Chapel Creek Drive in Santee, SC, where golf, lake living, and Lowcountry c...	4 beds \| 4 baths \| 3,720 sq.ft.	$570,000	Airbnb cash on cash: 5.08% Traditional cash on cash: 5.66% Airbnb Rental Income: $4603 Traditional Rental Income: $3957 Airbnb ROI: 5.08% Traditional ROI: 5.66%
126 Wateree Drive Santee, SC This beautiful brick home is perfectly situated on the scenic Santee Cooper Golf Course, o...	3 beds \| 3 baths \| 3,204 sq.ft.	$549,000	Airbnb cash on cash: -1.3% Traditional cash on cash: 1.28% Airbnb Rental Income: $1024 Traditional Rental Income: $1986 Airbnb ROI: -1.3% Traditional ROI: 1.28%
472 Santee Drive Santee, SC This custom-designed brick home is truly one-of-a-kind, offering more bells and whistles t...	5 beds \| 4 baths \| 4,046 sq.ft.	$550,000	Airbnb cash on cash: N/A Traditional cash on cash: 4.88% Airbnb Rental Income: $null Traditional Rental Income: $3558 Airbnb ROI: N/A Traditional ROI: 4.88%
724 Striped Bass Court Santee, SC Spacious New Home Near Lake Marion Welcome home to 724 Striped Bass Court, located in the ...	3 beds \| 3 baths \| 1,518 sq.ft.	$245,900	Airbnb cash on cash: 0.68% Traditional cash on cash: 4.57% Airbnb Rental Income: $1024 Traditional Rental Income: $1567 Airbnb ROI: 0.68% Traditional ROI: 4.57%
612 Santee Drive Santee, SC Are you looking for a second home? If so, this is the home for you! It is being sold compl...	3 beds \| 3 baths \| 2,019 sq.ft.	$350,000	Airbnb cash on cash: -1.05% Traditional cash on cash: 3.23% Airbnb Rental Income: $1024 Traditional Rental Income: $2071 Airbnb ROI: -1.05% Traditional ROI: 3.23%
609 Perch Lane Santee, SC Welcome home to 609 Perch Lane, set on an oversized lot in the heart of the Center Pointe ...	3 beds \| 3 baths \| 1,360 sq.ft.	$241,830	Airbnb cash on cash: 0.72% Traditional cash on cash: 4.53% Airbnb Rental Income: $1024 Traditional Rental Income: $1535 Airbnb ROI: 0.72% Traditional ROI: 4.53%
23 Peter Collinson Road Santee, SC Charming 3-bedroom, 2-bath ranch in the quiet, gated 55+ community of Bradford Village. Th...	3 beds \| 2 baths \| 2,276 sq.ft.	$279,900	Airbnb cash on cash: 0.36% Traditional cash on cash: 5.96% Airbnb Rental Income: $1024 Traditional Rental Income: $2140 Airbnb ROI: 0.36% Traditional ROI: 5.96%
724 Sinker Lane Santee, SC Welcome home to this this 10 month young single level retirement or starter home located a...	2 beds \| 2 baths \| 1,181 sq.ft.	$286,888	Airbnb cash on cash: 0.38% Traditional cash on cash: 4.4% Airbnb Rental Income: $1068 Traditional Rental Income: $1786 Airbnb ROI: 0.38% Traditional ROI: 4.4%
725 Striped Bass Court Santee, SC Welcome home to 725 Striped Bass Court, where comfort, connection, and Lowcountry living c...	3 beds \| 3 baths \| 1,518 sq.ft.	$245,900	Airbnb cash on cash: 0.68% Traditional cash on cash: 4.82% Airbnb Rental Income: $1024 Traditional Rental Income: $1626 Airbnb ROI: 0.68% Traditional ROI: 4.82%
600 Perch Lane Santee, SC Lowcountry Living in Centerpoint Welcome to 600 Perch Lane in the Center Pointe community ...	3 beds \| 2 baths \| 1,183 sq.ft.	$219,000	Airbnb cash on cash: 1.2% Traditional cash on cash: 5.93% Airbnb Rental Income: $1024 Traditional Rental Income: $1645 Airbnb ROI: 1.2% Traditional ROI: 5.93%
704 Striped Bass Court Santee, SC Centerpoint Ravenel SC New Home Opportunity Center Pointe is conveniently located in the h...	3 beds \| 3 baths \| 1,360 sq.ft.	$234,000	Airbnb cash on cash: 0.85% Traditional cash on cash: 4.77% Airbnb Rental Income: $1024 Traditional Rental Income: $1532 Airbnb ROI: 0.85% Traditional ROI: 4.77%
115 Wateree Drive Santee, SC Luxury meets lakeside living in this fully custom new construction home located in the pre...	5 beds \| 4 baths \| 2,633 sq.ft.	$699,000	Airbnb cash on cash: N/A Traditional cash on cash: 1.71% Airbnb Rental Income: $null Traditional Rental Income: $2388 Airbnb ROI: N/A Traditional ROI: 1.71%
138 Heatleys End Road Santee, SC Enjoy country living on this 10-acre property with two homes. Move-in ready - main brick h...	3 beds \| 2 baths \| 2,269 sq.ft.	$834,900	Airbnb cash on cash: -0.83% Traditional cash on cash: 0.67% Airbnb Rental Income: $1024 Traditional Rental Income: $1829 Airbnb ROI: -0.83% Traditional ROI: 0.67%
130 William Clark Boulevard Santee, SC Center Pointe is conveniently located in the heart of Santee, South Carolina, only minutes...	3 beds \| 3 baths \| 1,774 sq.ft.	$341,400	Airbnb cash on cash: 0.21% Traditional cash on cash: 4.38% Airbnb Rental Income: $1024 Traditional Rental Income: $2000 Airbnb ROI: 0.21% Traditional ROI: 4.38%
145 William Clark Boulevard Santee, SC Center Pointe is conveniently located in the heart of Santee, South Carolina, only minutes...	3 beds \| 3 baths \| 1,774 sq.ft.	$349,965	Airbnb cash on cash: 0.17% Traditional cash on cash: 4.26% Airbnb Rental Income: $1024 Traditional Rental Income: $2009 Airbnb ROI: 0.17% Traditional ROI: 4.26%
905 Bream Circle Santee, SC Newly Released! Looking for that spacious backyard? This lot with the Brandon floorplan ha...	3 beds \| 3 baths \| 1,518 sq.ft.	$293,120	Airbnb cash on cash: 0.68% Traditional cash on cash: 5.27% Airbnb Rental Income: $1024 Traditional Rental Income: $1933 Airbnb ROI: 0.68% Traditional ROI: 5.27%
605 Perch Lane Santee, SC New Construction in Santee SC \|Near Lake Marion & Golf Courses Welcome home to 605 Perch L...	2 beds \| 3 baths \| 1,360 sq.ft.	$289,900	Airbnb cash on cash: 0.48% Traditional cash on cash: 4.58% Airbnb Rental Income: $1068 Traditional Rental Income: $1819 Airbnb ROI: 0.48% Traditional ROI: 4.58%
601 Perch Lane Santee, SC Lowcountry Living in Centerpoint Welcome to 601 Perch Lane in the Center Pointe community ...	3 beds \| 2 baths \| 1,183 sq.ft.	$219,000	Airbnb cash on cash: 0.96% Traditional cash on cash: 4.77% Airbnb Rental Income: $1024 Traditional Rental Income: $1455 Airbnb ROI: 0.96% Traditional ROI: 4.77%
645 Perch Lane Santee, SC Santee SC 3-Bedroom Home for Sale \| Modern Living Near Lake Marion & Golf Welcome to 645 P...	3 beds \| 2 baths \| 1,183 sq.ft.	$221,500	Airbnb cash on cash: 0.93% Traditional cash on cash: 4.69% Airbnb Rental Income: $1024 Traditional Rental Income: $1453 Airbnb ROI: 0.93% Traditional ROI: 4.69%
700 Striped Bass Court Santee, SC Welcome home to 700 Striped Bass Court, where comfort, connection, and Lowcountry living c...	3 beds \| 3 baths \| 1,518 sq.ft.	$257,500	Airbnb cash on cash: 0.59% Traditional cash on cash: 4.55% Airbnb Rental Income: $1024 Traditional Rental Income: $1627 Airbnb ROI: 0.59% Traditional ROI: 4.55%
713 Striped Bass Court Santee, SC Welcome to 713 Striped Bass Lane, in the Center Pointe community of Santee, South Carolina...	3 beds \| 2 baths \| 1,183 sq.ft.	$216,500	Airbnb cash on cash: 0.98% Traditional cash on cash: 4.83% Airbnb Rental Income: $1024 Traditional Rental Income: $1453 Airbnb ROI: 0.98% Traditional ROI: 4.83%
424 Santee Drive Santee, SC Lake Marion Gated Golf Community offers home viewing Lake Marion. Come see this move-in re...	3 beds \| 3 baths \| 2,218 sq.ft.	$337,500	Airbnb cash on cash: 0.02% Traditional cash on cash: 5.25% Airbnb Rental Income: $1024 Traditional Rental Income: $2324 Airbnb ROI: 0.02% Traditional ROI: 5.25%

Your search for investment property begins and ends here

Single Family Homes for Sale in Santee, SC

370 Chapel Creek Drive

Santee, SC

4 beds | 4 baths | 3,720 sq.ft.

$570,000

Airbnb cash on cash: 5.08%

Traditional cash on cash: 5.66%

Airbnb Rental Income: $4603

Traditional Rental Income: $3957

Airbnb ROI: 5.08%

Traditional ROI: 5.66%

126 Wateree Drive

Santee, SC

3 beds | 3 baths | 3,204 sq.ft.

$549,000

Airbnb cash on cash: -1.3%

Traditional cash on cash: 1.28%

Airbnb Rental Income: $1024

Traditional Rental Income: $1986

Airbnb ROI: -1.3%

Traditional ROI: 1.28%

472 Santee Drive

Santee, SC

5 beds | 4 baths | 4,046 sq.ft.

$550,000

Airbnb cash on cash: N/A

Traditional cash on cash: 4.88%

Airbnb Rental Income: $null

Traditional Rental Income: $3558

Airbnb ROI: N/A

Traditional ROI: 4.88%

724 Striped Bass Court

Santee, SC

3 beds | 3 baths | 1,518 sq.ft.

$245,900

Airbnb cash on cash: 0.68%

Traditional cash on cash: 4.57%

Airbnb Rental Income: $1024

Traditional Rental Income: $1567

Airbnb ROI: 0.68%

Traditional ROI: 4.57%

612 Santee Drive

Santee, SC

3 beds | 3 baths | 2,019 sq.ft.

$350,000

Airbnb cash on cash: -1.05%

Traditional cash on cash: 3.23%

Airbnb Rental Income: $1024

Traditional Rental Income: $2071

Airbnb ROI: -1.05%

Traditional ROI: 3.23%

609 Perch Lane

Santee, SC

3 beds | 3 baths | 1,360 sq.ft.

$241,830

Airbnb cash on cash: 0.72%

Traditional cash on cash: 4.53%

Airbnb Rental Income: $1024

Traditional Rental Income: $1535

Airbnb ROI: 0.72%

Traditional ROI: 4.53%

23 Peter Collinson Road

Santee, SC

3 beds | 2 baths | 2,276 sq.ft.

$279,900

Airbnb cash on cash: 0.36%

Traditional cash on cash: 5.96%

Airbnb Rental Income: $1024

Traditional Rental Income: $2140

Airbnb ROI: 0.36%

Traditional ROI: 5.96%

724 Sinker Lane

Santee, SC

2 beds | 2 baths | 1,181 sq.ft.

$286,888

Airbnb cash on cash: 0.38%

Traditional cash on cash: 4.4%

Airbnb Rental Income: $1068

Traditional Rental Income: $1786

Airbnb ROI: 0.38%