Real Estate Investment Properties for Sale in Santee, SC

Looking for investment property in Santee, SC with high ROI ?

Explore a variety of short-term homes & houses in Santee, SC. Invest wisely with VRBO & Santee, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Single Family Homes for Sale in Santee, SC

Search for Single Family Residential for Sale in Santee, South Carolina. Browse all of Mashvisor’s Single Family Residential listings and other investment property types including Single Family Homes, Multi Family Homes, Condos, Townhouses and Other Homes.

Showing 27 Single Family Residential listings of over 500,000 total investment properties for sale. Visit Mashvisor.com to all investment properties.

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
370 Chapel Creek Drive Santee, SC Exquisite Custom Home with Golf and Pond Views in Desirable Chapel Creek. Welcome to 370 C...	4 beds \| 4 baths \| 3,720 sq.ft.	$585,500	Airbnb cash on cash: 2.16% Traditional cash on cash: 5.47% Airbnb Rental Income: $2802 Traditional Rental Income: $3957 Airbnb ROI: 2.16% Traditional ROI: 5.47%
126 Wateree Drive Santee, SC This beautiful brick home is perfectly situated on the scenic Santee Cooper Golf Course, o...	3 beds \| 3 baths \| 3,204 sq.ft.	$559,000	Airbnb cash on cash: -1.79% Traditional cash on cash: 1.24% Airbnb Rental Income: $711 Traditional Rental Income: $1986 Airbnb ROI: -1.79% Traditional ROI: 1.24%
472 Santee Drive Santee, SC This custom-designed brick home is truly one-of-a-kind, offering more bells and whistles t...	5 beds \| 4 baths \| 4,046 sq.ft.	$575,000	Airbnb cash on cash: -0.84% Traditional cash on cash: 4.6% Airbnb Rental Income: $990 Traditional Rental Income: $3558 Airbnb ROI: -0.84% Traditional ROI: 4.6%
900 Bream Circle Santee, SC Welcome to this gorgeous ranch-style Sullivan floorplan featuring 3 bedrooms, 2 baths and ...	3 beds \| 2 baths \| 1,183 sq.ft.	$249,850	Airbnb cash on cash: -0.15% Traditional cash on cash: 5.45% Airbnb Rental Income: $711 Traditional Rental Income: $1725 Airbnb ROI: -0.15% Traditional ROI: 5.45%
753 Striped Bass Court Santee, SC Welcome to this gorgeous ranch-style Sullivan floorplan featuring 3 bedrooms, 2 baths and ...	3 beds \| 2 baths \| 1,183 sq.ft.	$247,850	Airbnb cash on cash: -0.14% Traditional cash on cash: 5.51% Airbnb Rental Income: $711 Traditional Rental Income: $1725 Airbnb ROI: -0.14% Traditional ROI: 5.51%
908 Bream Circle Santee, SC Welcome home to the Helena, a beautifully designed one-story home nested in the cul-de-sac...	4 beds \| 2 baths \| 1,482 sq.ft.	$282,615	Airbnb cash on cash: 6.3% Traditional cash on cash: 5.42% Airbnb Rental Income: $2802 Traditional Rental Income: $1911 Airbnb ROI: 6.3% Traditional ROI: 5.42%
733 Striped Bass Court Santee, SC Welcome to single-story living at its best! This 4 bedroom, 2 bath Helena floorplan offers...	4 beds \| 2 baths \| 1,482 sq.ft.	$282,115	Airbnb cash on cash: 6.31% Traditional cash on cash: 5.43% Airbnb Rental Income: $2802 Traditional Rental Income: $1911 Airbnb ROI: 6.31% Traditional ROI: 5.43%
729 Striped Bass Court Santee, SC D.R. Horton's best-selling Cali floorplan! This single-story home captures the essence of ...	4 beds \| 2 baths \| 1,774 sq.ft.	$293,900	Airbnb cash on cash: 6.03% Traditional cash on cash: 5.66% Airbnb Rental Income: $2802 Traditional Rental Income: $2046 Airbnb ROI: 6.03% Traditional ROI: 5.66%
625 Perch Lane Santee, SC Welcome to this gorgeous ranch-style Sullivan floorplan featuring 3 bedrooms, 2 baths and ...	3 beds \| 2 baths \| 1,183 sq.ft.	$242,850	Airbnb cash on cash: -0.12% Traditional cash on cash: 5.64% Airbnb Rental Income: $711 Traditional Rental Income: $1725 Airbnb ROI: -0.12% Traditional ROI: 5.64%
728 Striped Bass Court Santee, SC D.R. Horton's best-selling Cali floorplan! This single-story home captures the essence of ...	4 beds \| 2 baths \| 1,774 sq.ft.	$289,900	Airbnb cash on cash: 6.12% Traditional cash on cash: 5.75% Airbnb Rental Income: $2802 Traditional Rental Income: $2046 Airbnb ROI: 6.12% Traditional ROI: 5.75%
657 Perch Lane Santee, SC Welcome to single-story living at its best! This 4 bedroom, 2 bath Helena floorplan offers...	4 beds \| 2 baths \| 1,482 sq.ft.	$264,850	Airbnb cash on cash: 6.78% Traditional cash on cash: 5.84% Airbnb Rental Income: $2802 Traditional Rental Income: $1911 Airbnb ROI: 6.78% Traditional ROI: 5.84%
748 Striped Bass Court Santee, SC Welcome to the Rachel! This home offers everything you're looking for in a functional two-...	3 beds \| 3 baths \| 1,360 sq.ft.	$279,900	Airbnb cash on cash: -0.24% Traditional cash on cash: 5.28% Airbnb Rental Income: $711 Traditional Rental Income: $1858 Airbnb ROI: -0.24% Traditional ROI: 5.28%
202 Trillium Court Santee, SC Waterfront condo, 2 bedrooms, 2 baths, overlooking the Santee State Park & Lake Marion the...	2 beds \| 2 baths \| 1,328 sq.ft.	$235,000	Airbnb cash on cash: -4.38% Traditional cash on cash: 3.08% Airbnb Rental Income: $581 Traditional Rental Income: $1953 Airbnb ROI: -4.38% Traditional ROI: 3.08%
220 Green Street Santee, SC Welcome to this charming manufactured home offering comfort, style, and modern upgrades. F...	3 beds \| 2 baths \| 1,375 sq.ft.	$205,000	Airbnb cash on cash: 0.25% Traditional cash on cash: 6.64% Airbnb Rental Income: $711 Traditional Rental Income: $1646 Airbnb ROI: 0.25% Traditional ROI: 6.64%
756 Santee River Road Santee, SC Country life is waiting! 202 acres and only 10 minutes from town. This estate sale home is...	3 beds \| 2 baths \| 1,782 sq.ft.	$225,000	Airbnb cash on cash: 0.44% Traditional cash on cash: 5.98% Airbnb Rental Income: $711 Traditional Rental Income: $1582 Airbnb ROI: 0.44% Traditional ROI: 5.98%
230 Oak Hollow Drive Santee, SC Your Lake Home Near Lake Marion! Embrace the perfect blend of comfort, and nature with thi...	3 beds \| 2 baths \| N/A	$230,000	Airbnb cash on cash: 0.33% Traditional cash on cash: 7.31% Airbnb Rental Income: $711 Traditional Rental Income: $1921 Airbnb ROI: 0.33% Traditional ROI: 7.31%
130 2nd Street Santee, SC Steps to Lake Marion! This fully renovated 3-bedroom, 2-bath ranch offers turnkey living i...	3 beds \| 2 baths \| 1,580 sq.ft.	$239,000	Airbnb cash on cash: -0.08% Traditional cash on cash: 5.97% Airbnb Rental Income: $711 Traditional Rental Income: $1772 Airbnb ROI: -0.08% Traditional ROI: 5.97%
612 Santee Drive Santee, SC PRICE REDUCTION! Don't miss an opportunity to view this immaculate second row home in gate...	3 beds \| 3 baths \| 2,019 sq.ft.	$395,000	Airbnb cash on cash: -1.75% Traditional cash on cash: 2.75% Airbnb Rental Income: $711 Traditional Rental Income: $2071 Airbnb ROI: -1.75% Traditional ROI: 2.75%
23 Peter Collinson Road Santee, SC Charming 3-bedroom, 2-bath ranch in the quiet, gated 55+ community of Bradford Village. Th...	3 beds \| 2 baths \| 2,276 sq.ft.	$289,900	Airbnb cash on cash: -0.19% Traditional cash on cash: 6.17% Airbnb Rental Income: $711 Traditional Rental Income: $2140 Airbnb ROI: -0.19% Traditional ROI: 6.17%
724 Sinker Lane Santee, SC Welcome home to this this 10 month young single level retirement or starter home located a...	2 beds \| 2 baths \| 1,181 sq.ft.	$292,888	Airbnb cash on cash: -1.13% Traditional cash on cash: 4.28% Airbnb Rental Income: $581 Traditional Rental Income: $1786 Airbnb ROI: -1.13% Traditional ROI: 4.28%
130 William Clark Boulevard Santee, SC Center Pointe is conveniently located in the heart of Santee, South Carolina, only minutes...	3 beds \| 3 baths \| 1,774 sq.ft.	$341,400	Airbnb cash on cash: -0.6% Traditional cash on cash: 4.38% Airbnb Rental Income: $711 Traditional Rental Income: $2000 Airbnb ROI: -0.6% Traditional ROI: 4.38%
164 William Clark Boulevard Santee, SC Conveniently located just an hour from Charleston, Santee is a quaint community surrounded...	3 beds \| 3 baths \| 2,388 sq.ft.	$300,000	Airbnb cash on cash: -0.64% Traditional cash on cash: 4.82% Airbnb Rental Income: $711 Traditional Rental Income: $1946 Airbnb ROI: -0.64% Traditional ROI: 4.82%
145 William Clark Boulevard Santee, SC Center Pointe is conveniently located in the heart of Santee, South Carolina, only minutes...	3 beds \| 3 baths \| 1,774 sq.ft.	$349,965	Airbnb cash on cash: -0.62% Traditional cash on cash: 4.26% Airbnb Rental Income: $711 Traditional Rental Income: $2009 Airbnb ROI: -0.62% Traditional ROI: 4.26%
905 Bream Circle Santee, SC Newly Released! Looking for that spacious backyard? This lot with the Brandon floorplan ha...	3 beds \| 3 baths \| 1,518 sq.ft.	$293,120	Airbnb cash on cash: -0.27% Traditional cash on cash: 5.27% Airbnb Rental Income: $711 Traditional Rental Income: $1933 Airbnb ROI: -0.27% Traditional ROI: 5.27%
111 Santee Cooper Santee, SC MAKE EVERY DAY A VACATION DAY! LOCATED IN SANTEE COOPER RESORT, A GATED, WATERFRONT AND GO...	4 beds \| 3 baths \| 1,908 sq.ft.	$305,000	Airbnb cash on cash: 4.12% Traditional cash on cash: 4.6% Airbnb Rental Income: $2802 Traditional Rental Income: $2285 Airbnb ROI: 4.12% Traditional ROI: 4.6%

Your search for investment property begins and ends here

Single Family Homes for Sale in Santee, SC

370 Chapel Creek Drive

Santee, SC

4 beds | 4 baths | 3,720 sq.ft.

$585,500

Airbnb cash on cash: 2.16%

Traditional cash on cash: 5.47%

Airbnb Rental Income: $2802

Traditional Rental Income: $3957

Airbnb ROI: 2.16%

Traditional ROI: 5.47%

126 Wateree Drive

Santee, SC

3 beds | 3 baths | 3,204 sq.ft.

$559,000

Airbnb cash on cash: -1.79%

Traditional cash on cash: 1.24%

Airbnb Rental Income: $711

Traditional Rental Income: $1986

Airbnb ROI: -1.79%

Traditional ROI: 1.24%

472 Santee Drive

Santee, SC

5 beds | 4 baths | 4,046 sq.ft.

$575,000

Airbnb cash on cash: -0.84%

Traditional cash on cash: 4.6%

Airbnb Rental Income: $990

Traditional Rental Income: $3558

Airbnb ROI: -0.84%

Traditional ROI: 4.6%

900 Bream Circle

Santee, SC

3 beds | 2 baths | 1,183 sq.ft.

$249,850

Airbnb cash on cash: -0.15%

Traditional cash on cash: 5.45%

Airbnb Rental Income: $711

Traditional Rental Income: $1725

Airbnb ROI: -0.15%

Traditional ROI: 5.45%

753 Striped Bass Court

Santee, SC

3 beds | 2 baths | 1,183 sq.ft.

$247,850

Airbnb cash on cash: -0.14%

Traditional cash on cash: 5.51%

Airbnb Rental Income: $711

Traditional Rental Income: $1725

Airbnb ROI: -0.14%

Traditional ROI: 5.51%

908 Bream Circle

Santee, SC

4 beds | 2 baths | 1,482 sq.ft.

$282,615

Airbnb cash on cash: 6.3%

Traditional cash on cash: 5.42%

Airbnb Rental Income: $2802

Traditional Rental Income: $1911

Airbnb ROI: 6.3%

Traditional ROI: 5.42%

733 Striped Bass Court

Santee, SC

4 beds | 2 baths | 1,482 sq.ft.

$282,115

Airbnb cash on cash: 6.31%

Traditional cash on cash: 5.43%

Airbnb Rental Income: $2802

Traditional Rental Income: $1911

Airbnb ROI: 6.31%

Traditional ROI: 5.43%

729 Striped Bass Court

Santee, SC

4 beds | 2 baths | 1,774 sq.ft.

$293,900

Airbnb cash on cash: 6.03%

Traditional cash on cash: 5.66%

Airbnb Rental Income: $2802

Traditional Rental Income: $2046

Airbnb ROI: 6.03%