Real Estate Investment Properties for Sale in Seneca, SC

Looking for investment property in Seneca, SC with high ROI ?

Explore a variety of short-term homes & houses in Seneca, SC. Invest wisely with VRBO & Seneca, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
623 W Springwood Drive Seneca, SC Charming, move-in-ready brick home on a fully fenced 0.47 of an acre lot bordering protect...	3 beds \| 2 baths \| N/A	$277,500	Airbnb cash on cash: 1.56% Traditional cash on cash: 5.03% Airbnb Rental Income: $1319 Traditional Rental Income: $1820 Airbnb ROI: 1.56% Traditional ROI: 5.03%
4306 Ashford Bluff Drive Seneca, SC Welcome to 4306 Ashford Bluff Dr., Seneca, SC. A beautiful home with wrap around porches, ...	3 beds \| 3 baths \| 3,144 sq.ft.	$550,000	Airbnb cash on cash: 0.02% Traditional cash on cash: 2.88% Airbnb Rental Income: $1319 Traditional Rental Income: $2377 Airbnb ROI: 0.02% Traditional ROI: 2.88%
256 Terrace View Way Seneca, SC The spacious home offers three large bedrooms and two full baths on the main level, as wel...	3 beds \| 2 baths \| 1,927 sq.ft.	$340,000	Airbnb cash on cash: 1.31% Traditional cash on cash: 5.66% Airbnb Rental Income: $1319 Traditional Rental Income: $2300 Airbnb ROI: 1.31% Traditional ROI: 5.66%
208 Terrace View Way Seneca, SC Looking for a move-in-ready 3-bedroom home in Shadowood subdivision near Clemson Universit...	3 beds \| 2 baths \| N/A	$340,000	Airbnb cash on cash: 1.22% Traditional cash on cash: 4.68% Airbnb Rental Income: $1319 Traditional Rental Income: $2015 Airbnb ROI: 1.22% Traditional ROI: 4.68%
9069 Fairview Church Road Seneca, SC MOTIVATED TO SELL. Lake Keowee views from this beautiful 4/5 BR, 3 Bath home. As you enter...	4 beds \| 3 baths \| 2,355 sq.ft.	$675,000	Airbnb cash on cash: 0.45% Traditional cash on cash: 1.83% Airbnb Rental Income: $1866 Traditional Rental Income: $2229 Airbnb ROI: 0.45% Traditional ROI: 1.83%
119 Oak Crest Circle Seneca, SC From the moment you drive down the long driveway surrounded by tall trees and greenery, it...	4 beds \| 6 baths \| N/A	$849,900	Airbnb cash on cash: 0.27% Traditional cash on cash: 6.69% Airbnb Rental Income: $1866 Traditional Rental Income: $6452 Airbnb ROI: 0.27% Traditional ROI: 6.69%
107 Silo Alley Seneca, SC Discover unparalleled comfort in this meticulously maintained 2017-built home, where moder...	3 beds \| 2 baths \| 1,909 sq.ft.	$385,000	Airbnb cash on cash: 1.05% Traditional cash on cash: 4.12% Airbnb Rental Income: $1319 Traditional Rental Income: $2022 Airbnb ROI: 1.05% Traditional ROI: 4.12%
609 Providence Point Drive Seneca, SC Welcome home to this spacious 4-bedroom, 2.5 bath residence situated on a desirable corner...	4 beds \| 3 baths \| 2,500 sq.ft.	$494,000	Airbnb cash on cash: 1.14% Traditional cash on cash: 3.37% Airbnb Rental Income: $1866 Traditional Rental Income: $2395 Airbnb ROI: 1.14% Traditional ROI: 3.37%
216 Riverbank Court Seneca, SC Don't miss this rare opportunity to own a beautifully crafted, Troyer built home in the de...	3 beds \| 3 baths \| 3,300 sq.ft.	$419,900	Airbnb cash on cash: 0.49% Traditional cash on cash: 3.61% Airbnb Rental Income: $1319 Traditional Rental Income: $2136 Airbnb ROI: 0.49% Traditional ROI: 3.61%
604 Feathery Lane Seneca, SC Positioned along the 6th fairway in the gated Cross Creek community, your 4 bedroom, 3.5 b...	4 beds \| 4 baths \| 2,701 sq.ft.	$537,500	Airbnb cash on cash: 0.84% Traditional cash on cash: 3.5% Airbnb Rental Income: $1866 Traditional Rental Income: $2705 Airbnb ROI: 0.84% Traditional ROI: 3.5%
109 Oak Crest Circle Seneca, SC Beautiful Home in prestige's subdivision of Stillwater, 5 minutes from Clemson University....	3 beds \| 2 baths \| 1,943 sq.ft.	$525,000	Airbnb cash on cash: 0.39% Traditional cash on cash: 2.79% Airbnb Rental Income: $1319 Traditional Rental Income: $2087 Airbnb ROI: 0.39% Traditional ROI: 2.79%
715 Bellview Way Seneca, SC End-unit townhouse offering 3 bedrooms and 2.5 baths, conveniently located minutes from do...	3 beds \| 3 baths \| N/A	$185,000	Airbnb cash on cash: 3% Traditional cash on cash: 9.43% Airbnb Rental Income: $1319 Traditional Rental Income: $2041 Airbnb ROI: 3% Traditional ROI: 9.43%
905 N Crestview Drive Seneca, SC This beautiful four-bedroom three bath home in Woodland Acres welcomes you with a spacious...	4 beds \| 3 baths \| N/A	$324,900	Airbnb cash on cash: 2.6% Traditional cash on cash: 6.35% Airbnb Rental Income: $1866 Traditional Rental Income: $2512 Airbnb ROI: 2.6% Traditional ROI: 6.35%
1298 Carradine Road Seneca, SC LAKE COMMUNITY with LAKE ACCESS less than 5 miles to Clemson campus and Death Valley! 1298...	3 beds \| 3 baths \| 2,146 sq.ft.	$369,000	Airbnb cash on cash: 0.91% Traditional cash on cash: 4.39% Airbnb Rental Income: $1319 Traditional Rental Income: $2118 Airbnb ROI: 0.91% Traditional ROI: 4.39%
851 Louie Lane Seneca, SC Newer roof, windows, and appliances! Welcome to this charming, single-level residence in t...	4 beds \| 2 baths \| 1,335 sq.ft.	$255,000	Airbnb cash on cash: 3.72% Traditional cash on cash: 4.88% Airbnb Rental Income: $1866 Traditional Rental Income: $1646 Airbnb ROI: 3.72% Traditional ROI: 4.88%
129 Shadowood Court Seneca, SC Fantastic Seneca location- Shadowood Subdivision just off of Hwy 123 with easy access to C...	3 beds \| 2 baths \| 1,900 sq.ft.	$314,500	Airbnb cash on cash: 1.09% Traditional cash on cash: 4.81% Airbnb Rental Income: $1319 Traditional Rental Income: $2011 Airbnb ROI: 1.09% Traditional ROI: 4.81%
1279 Coneross Point Drive Seneca, SC Back on the market at no fault of the seller! Ready for lake living or looking for a weeke...	3 beds \| 2 baths \| N/A	$494,900	Airbnb cash on cash: 0.57% Traditional cash on cash: 2.97% Airbnb Rental Income: $1319 Traditional Rental Income: $2024 Airbnb ROI: 0.57% Traditional ROI: 2.97%
227 Serenity Bay Drive Seneca, SC Welcome to your laid-back lake escape at 227 Serenity Bay on Lake Keowee -a warm, inviting...	4 beds \| 4 baths \| 2,755 sq.ft.	$865,000	Airbnb cash on cash: -0.56% Traditional cash on cash: 1.83% Airbnb Rental Income: $1866 Traditional Rental Income: $3293 Airbnb ROI: -0.56% Traditional ROI: 1.83%
731 Harts Cove Way Seneca, SC Welcome to 731 Harts Cove Way, this is a well maintained and thoughtfully cared for 3 bed,...	3 beds \| 3 baths \| N/A	$265,000	Airbnb cash on cash: 0.44% Traditional cash on cash: 4.75% Airbnb Rental Income: $1319 Traditional Rental Income: $1986 Airbnb ROI: 0.44% Traditional ROI: 4.75%
12010 W Camelia Lane Seneca, SC Tucked away on a quiet cul-de-sac in the Millbrook Subdivision, this beautifully updated 4...	4 beds \| 3 baths \| N/A	$400,000	Airbnb cash on cash: 1.93% Traditional cash on cash: 5.33% Airbnb Rental Income: $1866 Traditional Rental Income: $2640 Airbnb ROI: 1.93% Traditional ROI: 5.33%
212 Winding Lane Seneca, SC Welcome home! This 3 bedroom, 3.5 bath home sits on 2.3 fully fenced acres just minutes fr...	3 beds \| 4 baths \| N/A	$595,000	Airbnb cash on cash: 0.28% Traditional cash on cash: 3.42% Airbnb Rental Income: $1319 Traditional Rental Income: $2654 Airbnb ROI: 0.28% Traditional ROI: 3.42%
1612 Harts Ridge Drive Seneca, SC Discover the Ultimate Clemson Investment! This premium, ground level 4-bedroom, 4-full bat...	4 beds \| 4 baths \| N/A	$294,900	Airbnb cash on cash: 2.87% Traditional cash on cash: 9.15% Airbnb Rental Income: $1866 Traditional Rental Income: $3109 Airbnb ROI: 2.87% Traditional ROI: 9.15%
323 Meldau Road Seneca, SC Lakefront on a quite cove on Hartwell with a dock in place, and only minutes from Clemson ...	4 beds \| 3 baths \| N/A	$799,000	Airbnb cash on cash: 0.14% Traditional cash on cash: 1.16% Airbnb Rental Income: $1866 Traditional Rental Income: $2120 Airbnb ROI: 0.14% Traditional ROI: 1.16%
110 S Fairplay Street Seneca, SC Come experience the charm of this historical home located in the heart of downtown Seneca....	4 beds \| 4 baths \| N/A	$549,900	Airbnb cash on cash: 1.36% Traditional cash on cash: 4.79% Airbnb Rental Income: $1866 Traditional Rental Income: $3128 Airbnb ROI: 1.36% Traditional ROI: 4.79%
108 Oakway Drive Seneca, SC Welcome to 108 Oakway Drive, tucked away at the end of a quiet road, offering privacy, cha...	3 beds \| 2 baths \| 1,144 sq.ft.	$219,000	Airbnb cash on cash: 2.65% Traditional cash on cash: 5.78% Airbnb Rental Income: $1319 Traditional Rental Income: $1559 Airbnb ROI: 2.65% Traditional ROI: 5.78%
109 CAROLINA Cove Seneca, SC Welcome to 109 Carolina Cove, a beautifully maintained lakefront cabin nestled in the priv...	4 beds \| 3 baths \| N/A	$1,200,000	Airbnb cash on cash: -0.46% Traditional cash on cash: 0.96% Airbnb Rental Income: $1866 Traditional Rental Income: $2946 Airbnb ROI: -0.46% Traditional ROI: 0.96%
1133 Harts Ridge Drive Seneca, SC Calling All Investors, Clemson University Students, Parents & Fans! Don't miss this opport...	3 beds \| 3 baths \| N/A	$259,000	Airbnb cash on cash: 0.76% Traditional cash on cash: 5.44% Airbnb Rental Income: $1319 Traditional Rental Income: $2054 Airbnb ROI: 0.76% Traditional ROI: 5.44%
1614 Iroquois Drive Seneca, SC Move in ready! 1790 square foot home with 24'x28'detached garage and carport plus a fenced...	3 beds \| 2 baths \| 1,790 sq.ft.	$289,000	Airbnb cash on cash: 1.89% Traditional cash on cash: 5.88% Airbnb Rental Income: $1319 Traditional Rental Income: $1998 Airbnb ROI: 1.89% Traditional ROI: 5.88%
302 Meadowlark Lane Seneca, SC Donald Gardner beautiful custom style home on 2.96 acres and just a short drive to Lake Ke...	4 beds \| 4 baths \| 2,960 sq.ft.	$569,000	Airbnb cash on cash: 0.06% Traditional cash on cash: 3.65% Airbnb Rental Income: $1866 Traditional Rental Income: $3272 Airbnb ROI: 0.06% Traditional ROI: 3.65%
702 Bogey Boulevard Seneca, SC LIVE WHERE YOU PLAY - ELEVATED LIVING AT CROSS CREEK Tucked within the prestigious gated c...	3 beds \| 3 baths \| N/A	$500,000	Airbnb cash on cash: -0.61% Traditional cash on cash: 1.82% Airbnb Rental Income: $1319 Traditional Rental Income: $2049 Airbnb ROI: -0.61% Traditional ROI: 1.82%

Real Estate investment in Seneca, SC

There are 163 properties for sale in the city of Seneca . The median list price in Seneca is $417,000 and the average price per square foot is $170. In April 2026, the average monthly cash on cash return in Seneca is 3.00%. The average monthly rental income in Seneca is $2,018.

Seneca, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 163 investment properties available for sale in Seneca.

In 2026, the best neighborhood to buy investment property is Seneca.

The ROI for Short-Term is higher than the Long-Term in Seneca with average rental income of $1,319.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, SC

623 W Springwood Drive

Seneca, SC

3 beds | 2 baths | N/A

$277,500

Airbnb cash on cash: 1.56%

Traditional cash on cash: 5.03%

Airbnb Rental Income: $1319

Traditional Rental Income: $1820

Airbnb ROI: 1.56%

Traditional ROI: 5.03%

4306 Ashford Bluff Drive

Seneca, SC

3 beds | 3 baths | 3,144 sq.ft.

$550,000

Airbnb cash on cash: 0.02%

Traditional cash on cash: 2.88%

Airbnb Rental Income: $1319

Traditional Rental Income: $2377

Airbnb ROI: 0.02%

Traditional ROI: 2.88%

256 Terrace View Way

Seneca, SC

3 beds | 2 baths | 1,927 sq.ft.

$340,000

Airbnb cash on cash: 1.31%

Traditional cash on cash: 5.66%

Airbnb Rental Income: $1319

Traditional Rental Income: $2300

Airbnb ROI: 1.31%

Traditional ROI: 5.66%

208 Terrace View Way

Seneca, SC

3 beds | 2 baths | N/A

$340,000

Airbnb cash on cash: 1.22%

Traditional cash on cash: 4.68%

Airbnb Rental Income: $1319

Traditional Rental Income: $2015

Airbnb ROI: 1.22%

Traditional ROI: 4.68%

9069 Fairview Church Road

Seneca, SC

4 beds | 3 baths | 2,355 sq.ft.

$675,000

Airbnb cash on cash: 0.45%

Traditional cash on cash: 1.83%

Airbnb Rental Income: $1866

Traditional Rental Income: $2229

Airbnb ROI: 0.45%

Traditional ROI: 1.83%

119 Oak Crest Circle

Seneca, SC

4 beds | 6 baths | N/A

$849,900

Airbnb cash on cash: 0.27%

Traditional cash on cash: 6.69%

Airbnb Rental Income: $1866

Traditional Rental Income: $6452

Airbnb ROI: 0.27%

Traditional ROI: 6.69%

107 Silo Alley

Seneca, SC

3 beds | 2 baths | 1,909 sq.ft.

$385,000

Airbnb cash on cash: 1.05%

Traditional cash on cash: 4.12%

Airbnb Rental Income: $1319

Traditional Rental Income: $2022

Airbnb ROI: 1.05%

Traditional ROI: 4.12%

609 Providence Point Drive

Seneca, SC

4 beds | 3 baths | 2,500 sq.ft.

$494,000

Airbnb cash on cash: 1.14%

Traditional cash on cash: 3.37%

Airbnb Rental Income: $1866

Traditional Rental Income: $2395

Airbnb ROI: 1.14%