Airbnb Properties for Sale in Santee, SC

Looking for a vacation rental investment in Santee, SC with high ROI ?

Explore a range of newly added short-term rental homes in Santee, SC. Make a smart investment with newly available Airbnb properties and find the ideal high-ROI property for sale.

Airbnb For Sale in Santee, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
287 Santee Dr Santee, SC Waterfront home w/dock built in 2016 is located in Santee Cooper Resort, a gated waterfron...	4 beds \| 3 baths \| 2,786 sq.ft.	$849,900	Airbnb cash on cash: 2.72% Traditional cash on cash: 1.69% Airbnb Rental Income: $4603 Traditional Rental Income: $2829 Airbnb ROI: 2.72% Traditional ROI: 1.69%
440 Chapel Creek Dr Santee, SC PRICED TO SELL! The beautiful home is located on a lake at Chapel Creek Plantation, the h...	4 beds \| 2 baths \| 2,920 sq.ft.	$585,777	Airbnb cash on cash: 4.15% Traditional cash on cash: 1.69% Airbnb Rental Income: $4603 Traditional Rental Income: $2296 Airbnb ROI: 4.15% Traditional ROI: 1.69%
127 Cooper Cir Santee, SC Located in Santee Cooper Resort on Lake Marion. This home has 14 rooms (laundry room, uti...	4 beds \| 3 baths \| 3,386 sq.ft.	$499,900	Airbnb cash on cash: 4.19% Traditional cash on cash: 1.51% Airbnb Rental Income: $4603 Traditional Rental Income: $2394 Airbnb ROI: 4.19% Traditional ROI: 1.51%
116 William Clark Blvd Santee, SC Spacious 4-bedroom, 2-bath home located in the front of the neighborhood--just one block f...	4 beds \| 2 baths \| 1,768 sq.ft.	$325,000	Airbnb cash on cash: 9.91% Traditional cash on cash: 5.72% Airbnb Rental Income: $4603 Traditional Rental Income: $2366 Airbnb ROI: 9.91% Traditional ROI: 5.72%
106 Broad River Dr Santee, SC Easy home build process. PROPOSED CONSTRUCTION on DEEP WATER. ** Vacant Land/Lot also list...	4 beds \| 3 baths \| 2,600 sq.ft.	$743,000	Airbnb cash on cash: 3.57% Traditional cash on cash: 2.49% Airbnb Rental Income: $4603 Traditional Rental Income: $2903 Airbnb ROI: 3.57% Traditional ROI: 2.49%
119 Saluda Dr Santee, SC Experience the ultimate lake and golf lifestyle at 119 Saluda Drive, located in the sought...	4 beds \| 2 baths \| 3,055 sq.ft.	$499,900	Airbnb cash on cash: 5.62% Traditional cash on cash: 3.09% Airbnb Rental Income: $4603 Traditional Rental Income: $2466 Airbnb ROI: 5.62% Traditional ROI: 3.09%
0 Ellexlee Rd Santee, SC 0 Ellexlee Rd, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$150,000	Airbnb cash on cash: 8.06% Traditional cash on cash: 1.22% Airbnb Rental Income: $1996 Traditional Rental Income: $493 Airbnb ROI: 8.06% Traditional ROI: 1.22%
9387 Old Number Six Hwy Santee, SC 9387 Old Number Six Hwy, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$624,900	Airbnb cash on cash: 0.8% Traditional cash on cash: -0.88% Airbnb Rental Income: $1996 Traditional Rental Income: $493 Airbnb ROI: 0.8% Traditional ROI: -0.88%
0 William Clark Blvd Santee, SC 0 William Clark Blvd, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$325,000	Airbnb cash on cash: 2.95% Traditional cash on cash: -0.26% Airbnb Rental Income: $1996 Traditional Rental Income: $493 Airbnb ROI: 2.95% Traditional ROI: -0.26%
Ibis Point SE State Road S-38-754 Rd SE #Tract 2 Santee, SC Ibis Point SE State Road S-38-754 Rd SE #Tract 2, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$220,000	Airbnb cash on cash: 5.06% Traditional cash on cash: 0.76% Airbnb Rental Income: $1996 Traditional Rental Income: $578 Airbnb ROI: 5.06% Traditional ROI: 0.76%
000 Saluda Dr Santee, SC 000 Saluda Dr, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$125,000	Airbnb cash on cash: 8.62% Traditional cash on cash: 1.19% Airbnb Rental Income: $1996 Traditional Rental Income: $579 Airbnb ROI: 8.62% Traditional ROI: 1.19%
01 Santee Dr Santee, SC 01 Santee Dr, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$149,900	Airbnb cash on cash: 7.61% Traditional cash on cash: 1.24% Airbnb Rental Income: $1996 Traditional Rental Income: $562 Airbnb ROI: 7.61% Traditional ROI: 1.24%
Lot 2 Broad River Dr Santee, SC Lot 2 Broad River Dr, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$149,000	Airbnb cash on cash: 8.12% Traditional cash on cash: 1.89% Airbnb Rental Income: $1996 Traditional Rental Income: $587 Airbnb ROI: 8.12% Traditional ROI: 1.89%
220 Broad River Dr Santee, SC 220 Broad River Dr, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$300,000	Airbnb cash on cash: 2.76% Traditional cash on cash: -0.41% Airbnb Rental Income: $1996 Traditional Rental Income: $579 Airbnb ROI: 2.76% Traditional ROI: -0.41%

Vacation Rentals in Santee

There are 14 vacation rental properties available for sale in the city of Santee . The median list price of Airbnb properties available for sale in Santee is $294,024 and the average price per square foot is $180. The cash on cash return on vacation rentals in Santee is 1.00%. The average monthly short term rental income in Santee is $1,051.

Santee, SC Short Term Rentals FAQs for Buyers, Sellers and Investors

There are 14 Airbnb properties available for sale in Santee.

In 2026, the best neighborhood to buy short term rental property is Santee.

In September 2026, the average Airbnb occupancy rate in Santee is 18%.

Airbnb data on vacation rentals in Santee, SC is available at Mashvisor. You can access data such as listings, real-time pricing trends, Santee, SC market insights, guest information and booking details, seasonality trends and historical Santee, SC Airbnb performance data.

Your search for investment property begins and ends here

Airbnb For Sale in Santee, SC

287 Santee Dr

Santee, SC

4 beds | 3 baths | 2,786 sq.ft.

$849,900

Airbnb cash on cash: 2.72%

Traditional cash on cash: 1.69%

Airbnb Rental Income: $4603

Traditional Rental Income: $2829

Airbnb ROI: 2.72%

Traditional ROI: 1.69%

440 Chapel Creek Dr

Santee, SC

4 beds | 2 baths | 2,920 sq.ft.

$585,777

Airbnb cash on cash: 4.15%

Traditional cash on cash: 1.69%

Airbnb Rental Income: $4603

Traditional Rental Income: $2296

Airbnb ROI: 4.15%

Traditional ROI: 1.69%

127 Cooper Cir

Santee, SC

4 beds | 3 baths | 3,386 sq.ft.

$499,900

Airbnb cash on cash: 4.19%

Traditional cash on cash: 1.51%

Airbnb Rental Income: $4603

Traditional Rental Income: $2394

Airbnb ROI: 4.19%

Traditional ROI: 1.51%

116 William Clark Blvd

Santee, SC

4 beds | 2 baths | 1,768 sq.ft.

$325,000

Airbnb cash on cash: 9.91%

Traditional cash on cash: 5.72%

Airbnb Rental Income: $4603

Traditional Rental Income: $2366

Airbnb ROI: 9.91%

Traditional ROI: 5.72%

106 Broad River Dr

Santee, SC

4 beds | 3 baths | 2,600 sq.ft.

$743,000

Airbnb cash on cash: 3.57%

Traditional cash on cash: 2.49%

Airbnb Rental Income: $4603

Traditional Rental Income: $2903

Airbnb ROI: 3.57%

Traditional ROI: 2.49%

119 Saluda Dr

Santee, SC

4 beds | 2 baths | 3,055 sq.ft.

$499,900

Airbnb cash on cash: 5.62%

Traditional cash on cash: 3.09%

Airbnb Rental Income: $4603

Traditional Rental Income: $2466

Airbnb ROI: 5.62%

Traditional ROI: 3.09%

0 Ellexlee Rd

Santee, SC

N/A beds | N/A baths | N/A

$150,000

Airbnb cash on cash: 8.06%

Traditional cash on cash: 1.22%

Airbnb Rental Income: $1996

Traditional Rental Income: $493

Airbnb ROI: 8.06%

Traditional ROI: 1.22%

9387 Old Number Six Hwy

Santee, SC

N/A beds | N/A baths | N/A

$624,900

Airbnb cash on cash: 0.8%

Traditional cash on cash: -0.88%

Airbnb Rental Income: $1996

Traditional Rental Income: $493

Airbnb ROI: 0.8%