Airbnb Properties for Sale in Santee, SC

Looking for a vacation rental investment in Santee, SC with high ROI ?

Explore a range of newly added short-term rental homes in Santee, SC. Make a smart investment with newly available Airbnb properties and find the ideal high-ROI property for sale.

Airbnb For Sale in Santee, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
287 Santee Dr Santee, SC Waterfront home w/dock built in 2016 is located in Santee Cooper Resort, a gated waterfron...	4 beds \| 3 baths \| 2,786 sq.ft.	$849,900	Airbnb cash on cash: 1.89% Traditional cash on cash: 1.69% Airbnb Rental Income: $3816 Traditional Rental Income: $2829 Airbnb ROI: 1.89% Traditional ROI: 1.69%
440 Chapel Creek Dr Santee, SC PRICED TO SELL! The beautiful home is located on a lake at Chapel Creek Plantation, the h...	4 beds \| 2 baths \| 2,920 sq.ft.	$583,777	Airbnb cash on cash: 2.97% Traditional cash on cash: 1.69% Airbnb Rental Income: $3816 Traditional Rental Income: $2296 Airbnb ROI: 2.97% Traditional ROI: 1.69%
127 Cooper Cir Santee, SC Located in Santee Cooper Resort on Lake Marion. This home has 14 rooms (laundry room, uti...	4 beds \| 3 baths \| 3,386 sq.ft.	$480,000	Airbnb cash on cash: 2.95% Traditional cash on cash: 1.62% Airbnb Rental Income: $3816 Traditional Rental Income: $2394 Airbnb ROI: 2.95% Traditional ROI: 1.62%
116 William Clark Blvd Santee, SC Spacious 4-bedroom, 2-bath home located in the front of the neighborhood--just one block f...	4 beds \| 2 baths \| 1,768 sq.ft.	$320,000	Airbnb cash on cash: 7.9% Traditional cash on cash: 5.83% Airbnb Rental Income: $3816 Traditional Rental Income: $2366 Airbnb ROI: 7.9% Traditional ROI: 5.83%
106 Broad River Dr Santee, SC Easy home build process. PROPOSED CONSTRUCTION on DEEP WATER. ** Vacant Land/Lot also list...	4 beds \| 3 baths \| 2,600 sq.ft.	$743,000	Airbnb cash on cash: 2.62% Traditional cash on cash: 2.49% Airbnb Rental Income: $3816 Traditional Rental Income: $2903 Airbnb ROI: 2.62% Traditional ROI: 2.49%
119 Saluda Dr Santee, SC Experience the ultimate lake and golf lifestyle at 119 Saluda Drive, located in the sought...	4 beds \| 2 baths \| 3,055 sq.ft.	$499,900	Airbnb cash on cash: 4.22% Traditional cash on cash: 3.09% Airbnb Rental Income: $3816 Traditional Rental Income: $2466 Airbnb ROI: 4.22% Traditional ROI: 3.09%
343 Pinewood Dr Santee, SC Welcome to 343 Pinewood Dr, Santee, SC 29142 your gateway to lakeside living in the heart ...	4 beds \| 2 baths \| 2,332 sq.ft.	$260,000	Airbnb cash on cash: 9.24% Traditional cash on cash: 8.01% Airbnb Rental Income: $3816 Traditional Rental Income: $2690 Airbnb ROI: 9.24% Traditional ROI: 8.01%
Birch Plan Santee, SC Birch Plan, Santee, SC 29142 \| Single Family Residential	4 beds \| 2 baths \| 1,680 sq.ft.	$284,990	Airbnb cash on cash: 9.23% Traditional cash on cash: 3.99% Airbnb Rental Income: $3816 Traditional Rental Income: $1586 Airbnb ROI: 9.23% Traditional ROI: 3.99%
Cali Plan Santee, SC	4 beds \| 2 baths \| 1,774 sq.ft.	$285,200	Airbnb cash on cash: 9.22% Traditional cash on cash: 4.18% Airbnb Rental Income: $3816 Traditional Rental Income: $1638 Airbnb ROI: 9.22% Traditional ROI: 4.18%
9387 Old Number Six Hwy Santee, SC 9387 Old Number Six Hwy, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$624,900	Airbnb cash on cash: 1.65% Traditional cash on cash: -0.88% Airbnb Rental Income: $2593 Traditional Rental Income: $493 Airbnb ROI: 1.65% Traditional ROI: -0.88%
0 State Dr Santee, SC 0 State Dr, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$1,250,000	Airbnb cash on cash: 0.05% Traditional cash on cash: -1.24% Airbnb Rental Income: $2593 Traditional Rental Income: $476 Airbnb ROI: 0.05% Traditional ROI: -1.24%
0 William Clark Blvd Santee, SC 0 William Clark Blvd, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$325,000	Airbnb cash on cash: 4.58% Traditional cash on cash: -0.26% Airbnb Rental Income: $2593 Traditional Rental Income: $493 Airbnb ROI: 4.58% Traditional ROI: -0.26%
00 Highway 301 & 15 Santee, SC 00 Highway 301 & 15, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$1,255,000	Airbnb cash on cash: 0.04% Traditional cash on cash: -1.15% Airbnb Rental Income: $2593 Traditional Rental Income: $578 Airbnb ROI: 0.04% Traditional ROI: -1.15%
0 Five Chop Rd Santee, SC 0 Five Chop Rd, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$1,013,100	Airbnb cash on cash: 0.43% Traditional cash on cash: -1.05% Airbnb Rental Income: $2593 Traditional Rental Income: $578 Airbnb ROI: 0.43% Traditional ROI: -1.05%
7533 Old Number Six Hwy Santee, SC 7533 Old Number Six Hwy, Santee, SC 29142 \| Manufactured Home	4 beds \| 2 baths \| 2,302 sq.ft.	$269,900	Airbnb cash on cash: 9.82% Traditional cash on cash: 5.22% Airbnb Rental Income: $3816 Traditional Rental Income: $1820 Airbnb ROI: 9.82% Traditional ROI: 5.22%
9133 SW Ace Dr Santee, SC 9133 SW Ace Dr, Santee, SC 29142 \| Single Family Residential	4 beds \| 2 baths \| 2,176 sq.ft.	$297,990	Airbnb cash on cash: 8.46% Traditional cash on cash: 4.89% Airbnb Rental Income: $3816 Traditional Rental Income: $1988 Airbnb ROI: 8.46% Traditional ROI: 4.89%
Ibis Point SE State Road S-38-754 Rd SE #Tract 2 Santee, SC Ibis Point SE State Road S-38-754 Rd SE #Tract 2, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$220,000	Airbnb cash on cash: 7.45% Traditional cash on cash: 0.76% Airbnb Rental Income: $2593 Traditional Rental Income: $578 Airbnb ROI: 7.45% Traditional ROI: 0.76%
134 Cooper Cir Santee, SC 134 Cooper Cir, Santee, SC 29142 \| Single Family Residential	4 beds \| 2 baths \| 2,444 sq.ft.	$300,000	Airbnb cash on cash: 8.13% Traditional cash on cash: 4.68% Airbnb Rental Income: $3816 Traditional Rental Income: $2016 Airbnb ROI: 8.13% Traditional ROI: 4.68%
3453 Old State Rd Santee, SC 3453 Old State Rd, Santee, SC 29142 \| Manufactured Home	4 beds \| 2 baths \| 2,040 sq.ft.	$269,000	Airbnb cash on cash: 9.85% Traditional cash on cash: 5.61% Airbnb Rental Income: $3816 Traditional Rental Income: $1914 Airbnb ROI: 9.85% Traditional ROI: 5.61%
220 Broad River Dr Santee, SC 220 Broad River Dr, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$300,000	Airbnb cash on cash: 4.52% Traditional cash on cash: -0.41% Airbnb Rental Income: $2593 Traditional Rental Income: $579 Airbnb ROI: 4.52% Traditional ROI: -0.41%
142 Shuler St Santee, SC 142 Shuler St, Santee, SC 29142 \| Single Family Residential	2 beds \| 1 baths \| 2,640 sq.ft.	$149,900	Airbnb cash on cash: 4.8% Traditional cash on cash: 4.49% Airbnb Rental Income: $1435 Traditional Rental Income: $962 Airbnb ROI: 4.8% Traditional ROI: 4.49%
139 Santell Ct Santee, SC 139 Santell Ct, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$275,000	Airbnb cash on cash: 5.68% Traditional cash on cash: 0.32% Airbnb Rental Income: $2593 Traditional Rental Income: $582 Airbnb ROI: 5.68% Traditional ROI: 0.32%
000 Saluda Dr #7 Lots Santee, SC 000 Saluda Dr #7 Lots, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$888,000	Airbnb cash on cash: 0.52% Traditional cash on cash: -1.16% Airbnb Rental Income: $2593 Traditional Rental Income: $582 Airbnb ROI: 0.52% Traditional ROI: -1.16%
0 Putterway Ct Santee, SC 0 Putterway Ct, Santee, SC 29142 \| Other	N/A beds \| N/A baths \| N/A	$400,000	Airbnb cash on cash: 3.44% Traditional cash on cash: -0.24% Airbnb Rental Income: $2593 Traditional Rental Income: $590 Airbnb ROI: 3.44% Traditional ROI: -0.24%

Vacation Rentals in Santee

There are 24 vacation rental properties available for sale in the city of Santee . The median list price of Airbnb properties available for sale in Santee is $294,024 and the average price per square foot is $180. The cash on cash return on vacation rentals in Santee is 2.00%. The average monthly short term rental income in Santee is $1,435.

Santee, SC Short Term Rentals FAQs for Buyers, Sellers and Investors

There are 24 Airbnb properties available for sale in Santee.

In 2026, the best neighborhood to buy short term rental property is Santee.

In October 2026, the average Airbnb occupancy rate in Santee is 24%.

Airbnb data on vacation rentals in Santee, SC is available at Mashvisor. You can access data such as listings, real-time pricing trends, Santee, SC market insights, guest information and booking details, seasonality trends and historical Santee, SC Airbnb performance data.

Your search for investment property begins and ends here

Airbnb For Sale in Santee, SC

287 Santee Dr

Santee, SC

4 beds | 3 baths | 2,786 sq.ft.

$849,900

Airbnb cash on cash: 1.89%

Traditional cash on cash: 1.69%

Airbnb Rental Income: $3816

Traditional Rental Income: $2829

Airbnb ROI: 1.89%

Traditional ROI: 1.69%

440 Chapel Creek Dr

Santee, SC

4 beds | 2 baths | 2,920 sq.ft.

$583,777

Airbnb cash on cash: 2.97%

Traditional cash on cash: 1.69%

Airbnb Rental Income: $3816

Traditional Rental Income: $2296

Airbnb ROI: 2.97%

Traditional ROI: 1.69%

127 Cooper Cir

Santee, SC

4 beds | 3 baths | 3,386 sq.ft.

$480,000

Airbnb cash on cash: 2.95%

Traditional cash on cash: 1.62%

Airbnb Rental Income: $3816

Traditional Rental Income: $2394

Airbnb ROI: 2.95%

Traditional ROI: 1.62%

116 William Clark Blvd

Santee, SC

4 beds | 2 baths | 1,768 sq.ft.

$320,000

Airbnb cash on cash: 7.9%

Traditional cash on cash: 5.83%

Airbnb Rental Income: $3816

Traditional Rental Income: $2366

Airbnb ROI: 7.9%

Traditional ROI: 5.83%

106 Broad River Dr

Santee, SC

4 beds | 3 baths | 2,600 sq.ft.

$743,000

Airbnb cash on cash: 2.62%

Traditional cash on cash: 2.49%

Airbnb Rental Income: $3816

Traditional Rental Income: $2903

Airbnb ROI: 2.62%

Traditional ROI: 2.49%

119 Saluda Dr

Santee, SC

4 beds | 2 baths | 3,055 sq.ft.

$499,900

Airbnb cash on cash: 4.22%

Traditional cash on cash: 3.09%

Airbnb Rental Income: $3816

Traditional Rental Income: $2466

Airbnb ROI: 4.22%

Traditional ROI: 3.09%

343 Pinewood Dr

Santee, SC

4 beds | 2 baths | 2,332 sq.ft.

$260,000

Airbnb cash on cash: 9.24%

Traditional cash on cash: 8.01%

Airbnb Rental Income: $3816

Traditional Rental Income: $2690

Airbnb ROI: 9.24%

Traditional ROI: 8.01%

Birch Plan

Santee, SC

4 beds | 2 baths | 1,680 sq.ft.

$284,990

Airbnb cash on cash: 9.23%

Traditional cash on cash: 3.99%

Airbnb Rental Income: $3816

Traditional Rental Income: $1586

Airbnb ROI: 9.23%