Real Estate Investment Properties for Sale in Santee, SC
Looking for investment property in Santee, SC with high ROI ?
Explore a variety of short-term homes & houses in Santee, SC. Invest wisely with VRBO & Santee, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.
Investment Property for Sale in Santee, SC
| PROPERTY | DETAILS | SALE PRICE | INVESTMENT PERFORMANCE |
|---|---|---|---|
104 Cooper DrSantee, SCIn Santee Cooper Resort, you purchase more than a home, you purchase a lifestyle. Nothing ... |
4 beds | 3 baths | 3,564 sq.ft. |
$385,000 |
Airbnb cash on cash: 4.18%
|
520 Trillium CtSantee, SCLake life is calling! Owning a Lake Marion condo puts you in the sweet spot of low-mainten... |
3 beds | 3 baths | 1,720 sq.ft. |
$300,000 |
Airbnb cash on cash: -3.69%
|
370 Chapel Creek DrSantee, SCWelcome to 370 Chapel Creek Drive in Santee, SC-a beautifully crafted 4-bedroom, 4-bathroo... |
4 beds | 4 baths | 3,720 sq.ft. |
$579,000 |
Airbnb cash on cash: 2.53%
|
126 Wateree DrSantee, SCThis beautiful brick home is perfectly situated on the scenic Santee Cooper Golf Course, o... |
3 beds | 2 baths | 3,204 sq.ft. |
$559,000 |
Airbnb cash on cash: -1.89%
|
125 Ballard LnSantee, SCEnjoy lake-area living just minutes from Lake Marion in the heart of Santee. This top-floo... |
2 beds | 2 baths | 1,298 sq.ft. |
$220,000 |
Airbnb cash on cash: -1.1%
|
127 Cooper CirSantee, SCLocated in Santee Cooper Resort on Lake Marion. This home has 14 rooms (laundry room, uti... |
4 beds | 3 baths | 3,386 sq.ft. |
$540,000 |
Airbnb cash on cash: 1.2%
|
229 Cooper DrSantee, SCWelcome home to this sanctuary nestled under a canopy of towering pine trees. The winding ... |
3 beds | 2 baths | 1,692 sq.ft. |
$314,999 |
Airbnb cash on cash: -0.8%
|
1 John Fothergill CirSantee, SCBeautifully maintained single story home located in Bradford Village a 55 & older gated co... |
2 beds | 2 baths | 1,501 sq.ft. |
$219,900 |
Airbnb cash on cash: -0.27%
|
507 Ballard LnSantee, SCWaterfront condo overlooking the Big Water! This two bedroom, two bath condo comes fully f... |
2 beds | 2 baths | 1,232 sq.ft. |
$269,876 |
Airbnb cash on cash: -1.88%
|
113 Ballard LnSantee, SCBeautiful Condominium on the lake in Santee. Dock area for recreational fun like boating a... |
2 beds | 2 baths | 1,298 sq.ft. |
$230,000 |
Airbnb cash on cash: -0.89%
|
116 William Clark BlvdSantee, SCSpacious 4-bedroom, 2-bath home located in the front of the neighborhood--just one block f... |
4 beds | 2 baths | 1,774 sq.ft. |
$320,000 |
Airbnb cash on cash: 5.7%
|
105 Ballard LnSantee, SCTurnkey waterfront condo overlooking Lake Marion--South Carolina's largest lake with acces... |
2 beds | 2 baths | 1,298 sq.ft. |
$279,000 |
Airbnb cash on cash: -1.43%
|
8495 Old Number Six HwySantee, SCHalf Acre Charming Lake Retreat Near Golf & Santee State Park! Don't miss this opportunity... |
2 beds | 1 baths | 800 sq.ft. |
$210,000 |
Airbnb cash on cash: 0.4%
|
106 Broad River DrSantee, SCEasy home build process. PROPOSED CONSTRUCTION on DEEP WATER. ** Vacant Land/Lot also list... |
4 beds | 3 baths | 2,600 sq.ft. |
$743,000 |
Airbnb cash on cash: 1.66%
|
125 Congaree CtSantee, SCThis home is a short sale! Come Fall in love with this beautiful move-in-ready 2023-built ... |
3 beds | 2 baths | 1,183 sq.ft. |
$242,000 |
Airbnb cash on cash: -0.63%
|
472 Santee DrSantee, SCThis custom-designed brick home is truly one-of-a-kind, offering more bells and whistles t... |
5 beds | 3 baths | 4,046 sq.ft. |
$575,000 |
Airbnb cash on cash: -0.68%
|
752 Striped Bass CtSantee, SCNewly Released! Looking for a home with a nice view? This lot with the Brandon floorplan h... |
3 beds | 2 baths | 1,517 sq.ft. |
$269,900 |
Airbnb cash on cash: -0.4%
|
125 Cooper DrSantee, SCYour Lakeside Retreat Awaits - 125 Cooper Drive, Santee, SC Welcome to 125 Cooper Drive-ne... |
4 beds | 3 baths | 2,674 sq.ft. |
$389,900 |
Airbnb cash on cash: 4.28%
|
118 Broad River DrSantee, SCWelcome to 118 Broad River Dr., an exquisitely renovated Contemporary European waterfront ... |
6 beds | 5 baths | 4,220 sq.ft. |
$849,000 |
Airbnb cash on cash: -0.95%
|
202 Trillium CtSantee, SCWaterfront condo, 2 bedrooms, 2 baths, overlooking the Santee State Park & Lake Marion the... |
2 beds | 2 baths | 1,328 sq.ft. |
$205,000 |
Airbnb cash on cash: -3.66%
|
119 Saluda DrSantee, SCExperience the ultimate lake and golf lifestyle at 119 Saluda Drive, located in the sought... |
4 beds | 2 baths | 3,055 sq.ft. |
$499,900 |
Airbnb cash on cash: 2.8%
|
457 Santee DrSantee, SCWelcome to luxury living on Lake Marion! Situated on the serene shores of Lake Marion this... |
4 beds | 3 baths | 3,778 sq.ft. |
$1,450,000 |
Airbnb cash on cash: -0.02%
|
220 Green StSantee, SCWelcome to this charming manufactured home offering comfort, style, and modern upgrades. F... |
3 beds | 2 baths | 1,375 sq.ft. |
$199,900 |
Airbnb cash on cash: 0.03%
|
208 Avocada DrSantee, SCNO HOA with a FRONT AND BACK YARD.3 bedroom , 2 bathroom with a front porch followed by a ... |
3 beds | 2 baths | 1,200 sq.ft. |
$244,999 |
Airbnb cash on cash: -0.16%
|
230 Oak Hollow DrSantee, SCYour Lake Home Near Lake Marion! Embrace the perfect blend of comfort, and nature with thi... |
3 beds | 2 baths | 1,792 sq.ft. |
$230,000 |
Airbnb cash on cash: 0.11%
|
192 Avocada DrSantee, SC192 Avocada Dr, Santee, SC 29142 | Single Family Residential |
3 beds | 2 baths | 1,200 sq.ft. |
$260,000 |
Airbnb cash on cash: -0.51%
|
190 Avocada Drive DrSantee, SC190 Avocada Drive Dr, Santee, SC 29142 | Single Family Residential |
3 beds | 2 baths | 1,200 sq.ft. |
$244,999 |
Airbnb cash on cash: -0.44%
|
214 Avocada DrSantee, SC214 Avocada Dr, Santee, SC 29142 | Single Family Residential |
3 beds | 2 baths | 1,200 sq.ft. |
$244,999 |
Airbnb cash on cash: -0.44%
|
Spruce PlanSantee, SCSpruce Plan, Santee, SC 29142 | Single Family Residential |
3 beds | 2 baths | 1,296 sq.ft. |
$253,990 |
Airbnb cash on cash: -0.48%
|
121 Congaree Ct CtSantee, SC121 Congaree Ct Ct, Santee, SC 29142 | Single Family Residential |
4 beds | 2 baths | 1,774 sq.ft. |
$295,000 |
Airbnb cash on cash: 6.28%
|
721 Striped Bass CtSantee, SC721 Striped Bass Ct, Santee, SC 29142 | Single Family Residential |
4 beds | 2 baths | 1,482 sq.ft. |
$258,900 |
Airbnb cash on cash: 7.38%
|
Fairview PlanSantee, SCFairview Plan, Santee, SC 29142 | Single Family Residential |
3 beds | 3 baths | 1,910 sq.ft. |
$299,990 |
Airbnb cash on cash: -0.64%
|
Tupelo PlanSantee, SCTupelo Plan, Santee, SC 29142 | Single Family Residential |
3 beds | 2 baths | 1,517 sq.ft. |
$274,990 |
Airbnb cash on cash: -0.56%
|
106 Santee Cooper AnxSantee, SC106 Santee Cooper Anx, Santee, SC 29142 | Single Family Residential |
3 beds | 3 baths | 2,771 sq.ft. |
$465,000 |
Airbnb cash on cash: -1.4%
|
Birch PlanSantee, SCBirch Plan, Santee, SC 29142 | Single Family Residential |
4 beds | 2 baths | 1,680 sq.ft. |
$271,990 |
Airbnb cash on cash: 7.14%
|
126 Congaree CtSantee, SC126 Congaree Ct, Santee, SC 29142 | Single Family Residential |
4 beds | 2 baths | 1,482 sq.ft. |
$250,000 |
Airbnb cash on cash: 7.69%
|
156 William Clark BlvdSantee, SC156 William Clark Blvd, Santee, SC 29142 | Single Family Residential |
5 beds | 3 baths | 2,646 sq.ft. |
$359,000 |
Airbnb cash on cash: 0.17%
|
342 Picard LoopSantee, SC342 Picard Loop, Santee, SC 29142 | Townhouse |
3 beds | 2 baths | 1,625 sq.ft. |
$218,500 |
Airbnb cash on cash: -1.25%
|
118 William Clark BlvdSantee, SC118 William Clark Blvd, Santee, SC 29142 | Single Family Residential |
3 beds | 3 baths | 2,507 sq.ft. |
$350,000 |
Airbnb cash on cash: -2.51%
|
724 Striped Bass CtSantee, SC724 Striped Bass Ct, Santee, SC 29142 | Single Family Residential |
3 beds | 2 baths | 1,517 sq.ft. |
$271,900 |
Airbnb cash on cash: -0.73%
|
Real Estate investment in Santee, SC
There are 111 properties for sale in the city of Santee . The median list price in Santee is $387,000 and the average price per square foot is $238. In May 2026, the average monthly cash on cash return in Santee is 4.00%. The average monthly rental income in Santee is $1,615.